Mus musculus

153 known processes

Apaf1

apoptotic peptidase activating factor 1

(Aliases: 6230400I06Rik,Apaf-1,mKIAA0413,fog,KIAA0413,Apaf1l)

Apaf1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of apoptotic signaling pathwayGO:2001235950.978
epithelial tube morphogenesisGO:00605623030.940
embryonic epithelial tube formationGO:00018381300.887
negative regulation of cell proliferationGO:00082852960.862
neural tube developmentGO:00219151600.850
spermatid differentiationGO:00485151150.783
Fly
epithelial tube formationGO:00721751300.774
positive regulation of protein phosphorylationGO:00019342420.773
morphogenesis of embryonic epitheliumGO:00163311590.768
protein palmitoylationGO:0018345140.752
skeletal system developmentGO:00015013560.749
cilium assemblyGO:0042384810.745
blood vessel morphogenesisGO:00485142850.727
regulation of cell activationGO:00508652890.722
embryonic organ morphogenesisGO:00485622760.688
neural tube closureGO:0001843900.651
regulation of lymphocyte activationGO:00512492400.637
actin cytoskeleton organizationGO:00300362200.630
limb developmentGO:00601731660.624
smoothened signaling pathwayGO:00072241050.622
appendage developmentGO:00487361660.613
regulation of actin cytoskeleton organizationGO:0032956840.594
fat cell differentiationGO:00454441600.584
renal system developmentGO:00720012250.572
apoptotic signaling pathwayGO:00971903060.548
regulation of transferase activityGO:00513382630.544
regulation of cellular amino acid metabolic processGO:000652150.542
urogenital system developmentGO:00016552610.526
myeloid cell differentiationGO:00300992330.523
sensory organ morphogenesisGO:00905962420.519
Fly
hair follicle developmentGO:0001942850.507
axon guidanceGO:00074111410.499
cell divisionGO:00513011200.497
germ cell developmentGO:00072811850.495
Fly
positive regulation of apoptotic processGO:00430652170.490
mitotic cell cycle processGO:19030471590.478
regionalizationGO:00030023370.460
negative regulation of molecular functionGO:00440922580.457
positive regulation of programmed cell deathGO:00430682180.455
neuron projection guidanceGO:00974851410.449
tube formationGO:00351481400.446
regulation of t cell activationGO:00508631700.443
digestive tract developmentGO:00485651900.421
gastrulationGO:00073691160.419
branching morphogenesis of an epithelial tubeGO:00487541590.412
kidney developmentGO:00018222130.408
stem cell proliferationGO:00720891170.407
respiratory tube developmentGO:00303231670.398
skin developmentGO:00435882200.389
formation of radial glial scaffoldsGO:002194340.387
respiratory system developmentGO:00605411900.386
keratinocyte differentiationGO:0030216480.384
stem cell differentiationGO:00488632680.375
morphogenesis of a branching epitheliumGO:00611381930.375
male gamete generationGO:00482322850.374
Fly
leukocyte differentiationGO:00025213420.369
digestive system developmentGO:00551232000.368
regulation of apoptotic signaling pathwayGO:20012331970.366
regulation of cellular catabolic processGO:00313292420.362
embryonic skeletal system developmentGO:00487061200.362
spermatid developmentGO:00072861080.358
Fly
glial cell apoptotic processGO:003434930.356
Fly
positive regulation of cell deathGO:00109422240.355
regulation of protein kinase activityGO:00458592320.354
cellular carbohydrate metabolic processGO:00442621190.351
lung developmentGO:00303241640.351
angiogenesisGO:00015252010.344
leukocyte proliferationGO:00706611720.342
regulation of cell migrationGO:00303342190.342
neural tube patterningGO:0021532430.338
negative regulation of cell activationGO:00508661110.335
single organismal cell cell adhesionGO:00163371310.334
ameboidal type cell migrationGO:00016671280.334
myeloid leukocyte differentiationGO:00025731190.329
regulation of fat cell differentiationGO:0045598810.325
protein processingGO:00164851630.322
appendage morphogenesisGO:00351071490.321
regulation of secretionGO:00510462740.319
peptidyl amino acid modificationGO:00181933360.313
epidermis developmentGO:00085441870.313
endodermal cell fate specificationGO:000171440.306
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.298
cell adhesionGO:00071553290.297
amine metabolic processGO:0009308450.297
response to light stimulusGO:00094161350.296
peptidyl tyrosine modificationGO:00182121450.294
hair cycleGO:0042633900.293
axonogenesisGO:00074092740.291
response to radiationGO:00093141650.287
Fly
forebrain radial glial cell differentiationGO:002186140.281
generation of precursor metabolites and energyGO:00060911030.281
regulation of hydrolase activityGO:00513362460.274
canonical wnt signaling pathway involved in heart developmentGO:006131630.274
regulation of epithelial cell proliferationGO:00506781410.264
t cell proliferationGO:00420981200.264
macrophage differentiationGO:0030225200.261
epithelial cell proliferationGO:00506731740.258
heart morphogenesisGO:00030071780.258
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.257
positive regulation of cellular amino acid metabolic processGO:004576430.256
gland developmentGO:00487323300.255
Fly
neural precursor cell proliferationGO:00613511210.253
regulation of kinase activityGO:00435492490.248
positive regulation of protein kinase activityGO:00458601440.241
purine nucleoside metabolic processGO:00422782410.238
Fly
gliogenesisGO:00420631410.238
regulation of mapk cascadeGO:00434082480.237
macromolecule catabolic processGO:00090572810.236
actin filament organizationGO:00070151130.230
regulation of organ morphogenesisGO:20000271440.224
Fly
developmental programmed cell deathGO:0010623410.220
Fly
regulation of ossificationGO:00302781120.220
regulation of t cell proliferationGO:0042129920.219
regulation of cell cycleGO:00517262810.219
regulation of membrane potentialGO:00423911920.216
regulation of cell divisionGO:0051302760.215
positive regulation of smoothened signaling pathwayGO:0045880230.204
cellular amine metabolic processGO:0044106440.200
regulation of cell morphogenesis involved in differentiationGO:00107691510.199
jak stat cascadeGO:0007259420.199
mitotic cell cycleGO:00002781950.198
regulation of bindingGO:00510981110.197
g protein coupled receptor signaling pathwayGO:00071862430.195
erythrocyte differentiationGO:0030218880.193
positive regulation of mapk cascadeGO:00434101700.193
dna catabolic process endonucleolyticGO:0000737150.192
positive regulation of hydrolase activityGO:00513451480.190
labyrinthine layer blood vessel developmentGO:0060716210.190
signal transduction in absence of ligandGO:0038034550.190
cellular response to dna damage stimulusGO:00069742070.187
epithelial cell developmentGO:00020641590.186
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.185
organelle localizationGO:00516401790.185
negative regulation of immune system processGO:00026832090.184
Fly
positive regulation of organelle organizationGO:00106381280.184
leukocyte homeostasisGO:0001776790.184
regulation of leukocyte differentiationGO:19021051590.184
stem cell developmentGO:00488642190.184
positive regulation of kinase activityGO:00336741550.182
regulation of cell adhesionGO:00301551540.180
cell migration involved in gastrulationGO:0042074130.179
aorta morphogenesisGO:0035909220.178
chemotaxisGO:00069352470.177
lamellipodium organizationGO:0097581290.176
single organism cell adhesionGO:00986021560.172
regulation of cell motilityGO:20001452360.166
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.165
regulation of antigen receptor mediated signaling pathwayGO:0050854290.164
canonical wnt signaling pathway involved in regulation of cell proliferationGO:004434030.163
negative regulation of planar cell polarity pathway involved in pericardium morphogenesisGO:200016610.162
regulation of neuron differentiationGO:00456642810.160
cardiac chamber developmentGO:00032051080.160
neural tube formationGO:00018411080.159
regulation of cellular response to stressGO:00801351590.158
regulation of myeloid cell differentiationGO:0045637960.157
establishment of tissue polarityGO:0007164280.157
negative regulation of lymphocyte activationGO:0051250910.156
transmission of nerve impulseGO:0019226760.154
anatomical structure homeostasisGO:00602491450.152
Fly
positive regulation of growthGO:00459271040.151
positive regulation of cell activationGO:00508671580.149
odontogenesis of dentin containing toothGO:0042475660.147
regulation of protein localizationGO:00328802310.146
regulation of cellular ketone metabolic processGO:0010565660.145
organelle assemblyGO:00709251770.144
hematopoietic progenitor cell differentiationGO:00022441430.143
wnt signaling pathway involved in somitogenesisGO:009024440.142
response to lipopolysaccharideGO:00324961280.140
cellular nitrogen compound catabolic processGO:00442702800.140
camera type eye developmentGO:00430102660.140
notch signaling pathwayGO:0007219710.139
axis elongation involved in somitogenesisGO:009024540.139
skeletal system morphogenesisGO:00487052030.138
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.138
cellular response to lipidGO:00713961450.138
protein localization to organelleGO:00333651850.137
immune effector processGO:00022523210.136
intrinsic apoptotic signaling pathwayGO:00971931320.136
establishment of organelle localizationGO:00516561220.136
midbrain hindbrain boundary morphogenesisGO:002155540.135
negative regulation of platelet derived growth factor receptor beta signaling pathwayGO:200058720.135
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100430.134
cell growthGO:00160491300.133
microtubule based processGO:00070172360.133
response to nutrient levelsGO:00316671090.133
Fly
muscle cell differentiationGO:00426922610.132
lateral inhibitionGO:004633110.132
spermatogenesisGO:00072832840.132
Fly
labyrinthine layer developmentGO:0060711490.129
negative regulation of epithelial cell proliferationGO:0050680640.128
somitogenesisGO:0001756690.128
regulation of secretion by cellGO:19035302490.127
cardiac chamber morphogenesisGO:0003206930.126
regulation of sequence specific dna binding transcription factor activityGO:00510901060.125
regulation of organelle organizationGO:00330432890.125
cardiac septum morphogenesisGO:0060411460.124
phagocytosisGO:0006909660.123
membrane organizationGO:00610242450.123
positive regulation of protein modification processGO:00314012990.122
rhythmic processGO:00485111740.121
multicellular organismal signalingGO:0035637910.120
cell fate commitmentGO:00451652100.119
protein secretionGO:00093061110.119
positive regulation of proteolysisGO:0045862850.119
lymphocyte proliferationGO:00466511640.119
morphogenesis of a branching structureGO:00017632030.118
retina vasculature development in camera type eyeGO:0061298170.118
regulation of cohesin localization to chromatinGO:007192210.117
cellular macromolecule catabolic processGO:00442652060.117
regulation of peptide transportGO:0090087910.117
peptide hormone secretionGO:00300721090.117
multicellular organism growthGO:00352641610.117
regulation of establishment of planar polarityGO:0090175280.116
cohesin localization to chromatinGO:007192110.116
peptidyl tyrosine phosphorylationGO:00181081430.116
hindbrain morphogenesisGO:0021575460.116
megakaryocyte differentiationGO:0030219260.116
negative regulation of phosphorylationGO:00423261660.116
negative regulation of lymphocyte proliferationGO:0050672450.115
developmental maturationGO:00217001930.114
regulation of actin filament based processGO:0032970990.113
regulation of cellular amine metabolic processGO:0033238200.113
positive regulation of leukocyte differentiationGO:1902107860.111
cellular component assembly involved in morphogenesisGO:00109271390.111
regulation of cell cycle processGO:00105641600.111
glial cell developmentGO:0021782540.111
digestive tract morphogenesisGO:00485461470.110
regulation of neuron projection developmentGO:00109751690.109
regulation of planar cell polarity pathway involved in ventricular septum morphogenesisGO:200014810.109
response to organonitrogen compoundGO:00102432460.109
telencephalon cell migrationGO:0022029550.108
cell cycle arrestGO:0007050370.107
positive regulation of secretionGO:00510471300.106
wound healingGO:00420601570.105
positive regulation of myeloid cell differentiationGO:0045639430.105
positive regulation of macrophage differentiationGO:004565150.105
forebrain developmentGO:00309003020.104
positive regulation of myeloid leukocyte differentiationGO:0002763260.103
organonitrogen compound biosynthetic processGO:19015661920.103
retina development in camera type eyeGO:00600411190.102
cilium morphogenesisGO:00602711020.102
cell type specific apoptotic processGO:00972852680.101
embryonic heart tube developmentGO:0035050650.101
mesenchyme developmentGO:00604851520.101
regulation of smoothened signaling pathwayGO:0008589580.101
nucleoside phosphate metabolic processGO:00067533380.100
embryonic skeletal system morphogenesisGO:0048704910.100
telencephalon developmentGO:00215371860.099
primary neural tube formationGO:0014020950.099
response to monosaccharideGO:0034284670.099
release of cytochrome c from mitochondriaGO:0001836230.099
forebrain cell migrationGO:0021885580.098
maintenance of locationGO:0051235890.098
regulation of cell growthGO:0001558910.098
neuroblast proliferationGO:0007405490.097
mesenchymal cell differentiationGO:00487621070.096
cell proliferation in forebrainGO:0021846300.096
odontogenesisGO:0042476780.096
protein localization to nucleusGO:00345041210.095
positive regulation of t cell activationGO:00508701010.094
development of primary sexual characteristicsGO:00451371430.093
homeostasis of number of cellsGO:00488722100.093
chromatin modificationGO:00165681870.092
embryonic placenta developmentGO:0001892980.092
ventricular septum morphogenesisGO:0060412270.092
embryonic heart tube morphogenesisGO:0003143510.092
hormone secretionGO:00468791280.092
nitrogen compound transportGO:00717052710.091
ventricular septum developmentGO:0003281420.090
cytokine productionGO:00018163190.090
cellular amino acid metabolic processGO:00065201030.090
Fly
positive regulation of cellular catabolic processGO:00313311480.090
cellular homeostasisGO:00197252400.090
Fly
negative regulation of cell developmentGO:00107211690.090
hair follicle morphogenesisGO:0031069290.089
regulation of neural precursor cell proliferationGO:2000177700.089
oocyte constructionGO:000730820.089
axon ensheathmentGO:0008366760.089
embryonic appendage morphogenesisGO:00351131260.088
purine ribonucleoside triphosphate catabolic processGO:00092071990.088
regulation of stem cell proliferationGO:0072091780.088
regulation of purine nucleotide metabolic processGO:19005421690.088
planar cell polarity pathway involved in cardiac muscle tissue morphogenesisGO:006135020.088
extrinsic apoptotic signaling pathwayGO:00971911260.087
cellular chemical homeostasisGO:00550822150.087
adult behaviorGO:00305341350.087
negative regulation of transcription involved in g1 s transition of mitotic cell cycleGO:007193010.087
t cell apoptotic processGO:0070231390.087
peptide secretionGO:00027901140.087
regulation of leukocyte proliferationGO:00706631210.087
regulation of cytoskeleton organizationGO:00514931220.086
fertilizationGO:00095661270.086
central nervous system neuron differentiationGO:00219531620.086
small gtpase mediated signal transductionGO:0007264970.085
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188540.085
regulation of cell projection organizationGO:00313442060.084
regulation of dna bindingGO:0051101390.084
pallium developmentGO:00215431200.084
kidney morphogenesisGO:0060993830.083
sensory perceptionGO:00076002450.082
purine containing compound metabolic processGO:00725213110.082
Fly
insulin secretionGO:0030073890.081
positive regulation of cysteine type endopeptidase activityGO:2001056390.080
regulation of response to dna damage stimulusGO:2001020340.079
positive regulation of gtp catabolic processGO:0033126850.079
glial cell differentiationGO:00100011310.079
regulation of peptidyl tyrosine phosphorylationGO:0050730930.079
gonad developmentGO:00084061410.079
protein catabolic processGO:00301632210.078
endodermal cell fate commitmentGO:0001711120.078
apoptotic dna fragmentationGO:000630970.078
regulation of endopeptidase activityGO:0052548890.078
forebrain neuron developmentGO:0021884300.077
response to alcoholGO:0097305480.077
tube closureGO:0060606910.076
oxidation reduction processGO:00551143420.076
sensory perception of soundGO:0007605970.076
organic hydroxy compound metabolic processGO:19016152030.076
Fly
negative regulation of glial cell proliferationGO:006025340.075
positive regulation of endopeptidase activityGO:0010950430.075
morphogenesis of an epithelial sheetGO:0002011270.074
monosaccharide metabolic processGO:00059961060.074
myeloid leukocyte activationGO:0002274830.074
ribonucleotide catabolic processGO:00092612080.073
regulation of gliogenesisGO:0014013500.073
somatic stem cell maintenanceGO:0035019470.073
ribonucleoside triphosphate metabolic processGO:00091992200.073
activation of mapkk activityGO:0000186150.073
positive regulation of t cell proliferationGO:0042102520.072
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.071
response to molecule of bacterial originGO:00022371430.071
muscle tissue developmentGO:00605373080.071
positive regulation of cytokine productionGO:00018191740.071
t cell activationGO:00421102890.071
negative regulation of astrocyte differentiationGO:0048712100.071
neuron projection extensionGO:1990138640.070
regulation of peptide hormone secretionGO:0090276750.069
regulation of hematopoietic progenitor cell differentiationGO:1901532180.069
osteoclast differentiationGO:0030316620.069
multi multicellular organism processGO:00447061090.069
regulation of mitotic cell cycleGO:00073461260.069
regulation of cellular response to growth factor stimulusGO:0090287820.069
positive regulation of ossificationGO:0045778470.068
skin morphogenesisGO:0043589380.068
bone remodelingGO:0046849530.068
platelet derived growth factor receptor beta signaling pathwayGO:003579140.067
transforming growth factor beta receptor signaling pathwayGO:0007179710.067
ossificationGO:00015032160.067
regulation of protein serine threonine kinase activityGO:00719001570.065
detection of abiotic stimulusGO:0009582600.065
multicellular organismal homeostasisGO:00488711640.065
molting cycleGO:0042303900.064
stress activated protein kinase signaling cascadeGO:0031098810.064
eye photoreceptor cell differentiationGO:0001754410.064
lipoprotein metabolic processGO:0042157430.064
proteoglycan biosynthetic processGO:0030166200.064
negative regulation of neuron differentiationGO:00456651010.064
forebrain generation of neuronsGO:0021872630.063
cell chemotaxisGO:0060326810.063
hexose metabolic processGO:0019318980.063
face developmentGO:0060324380.063
cerebral cortex cell migrationGO:0021795440.063
regulation of lymphocyte apoptotic processGO:0070228410.063
mapk cascadeGO:00001652810.063
negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesisGO:200014910.063
b cell activationGO:00421131610.063
purine ribonucleoside metabolic processGO:00461282410.063
Fly
cellular protein complex assemblyGO:00436231160.063
positive regulation of nervous system developmentGO:00519622210.063
glucose homeostasisGO:00425931280.062
regulation of peptide secretionGO:0002791770.062
regulation of proteolysisGO:00301621640.062
developmental cell growthGO:0048588840.062
circulatory system processGO:00030131970.062
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.062
organic cyclic compound catabolic processGO:19013612950.061
retina morphogenesis in camera type eyeGO:0060042450.061
midbrain hindbrain boundary developmentGO:003091790.060
actin polymerization or depolymerizationGO:0008154540.060
cytoplasmic transportGO:00164822340.060
apoptotic mitochondrial changesGO:0008637480.060
action potentialGO:0001508780.060
regulation of cytokine productionGO:00018172660.060
regulation of vesicle mediated transportGO:00606271390.060
heterocycle catabolic processGO:00467002800.060
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573690.060
embryonic olfactory bulb interneuron precursor migrationGO:002183120.059
erk1 and erk2 cascadeGO:0070371770.059
regulation of apoptotic dna fragmentationGO:190251050.059
regulation of nucleoside metabolic processGO:00091181300.059
epithelial to mesenchymal transitionGO:0001837470.059
purine nucleotide metabolic processGO:00061633020.059
positive regulation of cellular amine metabolic processGO:003324050.059
regulation of cellular component biogenesisGO:00440871810.059
cellular response to monosaccharide stimulusGO:0071326470.059
neural crest formationGO:001402920.059
nephron developmentGO:00720061090.058
inner ear receptor cell differentiationGO:0060113610.058
cerebellum developmentGO:0021549770.058
negative regulation of cell fate specificationGO:000999640.058
cardiac ventricle developmentGO:0003231830.058
hindbrain radial glia guided cell migrationGO:0021932120.058
positive regulation of cell developmentGO:00107202370.058
Fly
response to acid chemicalGO:00011011110.058
ear developmentGO:00435832000.058
carbohydrate homeostasisGO:00335001280.058
regulation of macrophage differentiationGO:004564990.057
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.057
positive regulation of stem cell proliferationGO:2000648590.057
muscle contractionGO:00069361010.057
canonical wnt signaling pathwayGO:00600701300.057
positive regulation of lymphocyte activationGO:00512511400.057
transmembrane transportGO:00550854120.056
regulation of lipase activityGO:0060191150.056
negative regulation of leukocyte proliferationGO:0070664460.056
regulation of osteoblast proliferationGO:0033688150.056
renal tubule developmentGO:0061326870.056
regulation of interleukin 1 productionGO:0032652260.056
hepatocyte apoptotic processGO:0097284110.055
somite developmentGO:0061053810.055
purine ribonucleoside triphosphate metabolic processGO:00092052200.055
negative regulation of growthGO:0045926990.055
adenylate cyclase inhibiting g protein coupled receptor signaling pathwayGO:0007193200.055
myelinationGO:0042552740.055
somite specificationGO:000175740.055
stem cell maintenanceGO:00198271300.055
regulation of antibacterial peptide biosynthetic processGO:000280810.055
establishment of protein localization to organelleGO:00725941180.054
leukocyte migrationGO:00509001240.054
positive regulation of map kinase activityGO:0043406840.054
oogenesisGO:0048477560.054
regulation of phospholipase a2 activityGO:003242930.053
rho protein signal transductionGO:0007266320.053
regulation of hormone levelsGO:00108172110.053
negative regulation of synaptic vesicle exocytosisGO:200030130.053
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.053
positive regulation of transferase activityGO:00513471670.053
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631190.052
lymphocyte differentiationGO:00300982420.052
establishment or maintenance of cell polarityGO:0007163860.052
microtubule cytoskeleton organizationGO:00002261570.052
negative regulation of nervous system developmentGO:00519611560.052
antigen receptor mediated signaling pathwayGO:0050851640.052
regulation of cardiac cell fate specificationGO:200004310.051
positive regulation of bone resorptionGO:0045780130.051
epithelial cell morphogenesisGO:0003382410.051
positive regulation of rac gtpase activityGO:0032855140.051
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesisGO:200016410.051
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.051
mesonephric tubule developmentGO:0072164940.051
blood vessel remodelingGO:0001974330.051
activation of immune responseGO:00022531380.051
cellular lipid metabolic processGO:00442553230.051
ensheathment of neuronsGO:0007272760.051
carbohydrate derivative biosynthetic processGO:19011371830.050
positive regulation of neuron apoptotic processGO:0043525250.050
b cell homeostasisGO:0001782340.050
mammary gland epithelium developmentGO:0061180650.050
cellular polysaccharide metabolic processGO:0044264380.050
leukocyte apoptotic processGO:0071887710.049
regulation of lymphocyte proliferationGO:00506701170.049
negative regulation of cellular protein metabolic processGO:00322692470.049
regulation of chemotaxisGO:0050920530.049
regulation of exocytosisGO:0017157610.049
regulation of system processGO:00440572000.048
regulation of transcription involved in g1 s transition of mitotic cell cycleGO:000008330.048
response to peptideGO:19016521360.048
positive regulation of protein secretionGO:0050714520.048
protein autophosphorylationGO:0046777610.048
negative regulation of neuron projection developmentGO:0010977500.047
cellular component disassembly involved in execution phase of apoptosisGO:000692190.047
determination of heart left right asymmetryGO:0061371480.047
single organism nuclear importGO:1902593950.046
ureteric bud morphogenesisGO:0060675620.046
ureteric bud developmentGO:0001657940.046
branching involved in ureteric bud morphogenesisGO:0001658560.046
cardiac septum developmentGO:0003279590.046
dna metabolic processGO:00062593030.045
intracellular protein transportGO:00068862040.045
formation of primary germ layerGO:0001704770.045
regulation of embryonic developmentGO:0045995710.045
blood circulationGO:00080151950.045
positive regulation of cell adhesionGO:0045785800.045
protein import into nucleusGO:0006606950.045
blastocyst developmentGO:0001824800.045
i kappab kinase nf kappab signalingGO:0007249850.045
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.045
synaptic vesicle transportGO:0048489570.045
retinal ganglion cell axon guidanceGO:0031290180.045
carbohydrate metabolic processGO:00059752300.044
lung morphogenesisGO:0060425500.044

Apaf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
gastrointestinal system cancerDOID:311900.159
cancerDOID:16200.159
disease of cellular proliferationDOID:1456600.159
organ system cancerDOID:005068600.159