Mus musculus

0 known processes

Gba

glucosidase, beta, acid

(Aliases: GBA1,betaGC,GC,GLUC,GCase)

Gba biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
membrane lipid metabolic processGO:0006643530.339
Human
cellular ketone metabolic processGO:0042180840.298
sphingolipid metabolic processGO:0006665450.287
Human
ion transmembrane transportGO:00342203610.217
lysosome organizationGO:0007040210.194
organonitrogen compound catabolic processGO:19015652640.163
Human
cellular lipid catabolic processGO:0044242520.156
Human
lipid localizationGO:00108761260.143
defense response to other organismGO:00985421970.138
growth of symbiont in hostGO:0044117230.129
regulation of cellular amine metabolic processGO:0033238200.123
endocytosisGO:00068971680.121
defense response to gram positive bacteriumGO:0050830500.121
lytic vacuole organizationGO:0080171210.120
cellular amine metabolic processGO:0044106440.112
regulation of protein transportGO:00512231630.101
regulation of cellular component biogenesisGO:00440871810.100
cellular amino acid metabolic processGO:00065201030.100
glycerolipid catabolic processGO:0046503160.098
positive regulation of cholesterol storageGO:001088630.097
cellular lipid metabolic processGO:00442553230.096
Human
organic anion transportGO:00157111370.096
vacuole organizationGO:0007033380.096
macromolecule catabolic processGO:00090572810.096
negative regulation of growthGO:0045926990.095
ameboidal type cell migrationGO:00016671280.088
lipid transportGO:0006869980.087
negative regulation of cellular protein metabolic processGO:00322692470.087
Human
ceramide metabolic processGO:0006672310.086
Human
peptidyl amino acid modificationGO:00181933360.083
tissue migrationGO:0090130680.082
cation homeostasisGO:00550802120.082
regulation of protein localizationGO:00328802310.081
phagocytosisGO:0006909660.079
triglyceride metabolic processGO:0006641510.078
neutral lipid metabolic processGO:0006638570.073
regulation of cellular amino acid metabolic processGO:000652150.073
response to bacterial lipopeptideGO:007033930.069
muscle tissue developmentGO:00605373080.069
meiotic nuclear divisionGO:00071261150.069
lipid biosynthetic processGO:00086101790.068
Human
growth of symbiont involved in interaction with hostGO:0044116230.066
amine metabolic processGO:0009308450.065
regulation of proteolysisGO:00301621640.063
peptide metabolic processGO:0006518460.061
regulation of membrane potentialGO:00423911920.061
negative regulation of inflammatory response to antigenic stimulusGO:0002862100.061
regulation of cellular ketone metabolic processGO:0010565660.060
lipid catabolic processGO:0016042690.060
Human
reactive oxygen species metabolic processGO:0072593840.058
glycosphingolipid catabolic processGO:004647950.056
Human
multi multicellular organism processGO:00447061090.056
small molecule catabolic processGO:0044282710.055
interspecies interaction between organismsGO:0044419830.052
transmembrane transportGO:00550854120.052
modulation of growth of symbiont involved in interaction with hostGO:0044144190.052
arp2 3 complex mediated actin nucleationGO:003431430.052
defense response to bacteriumGO:00427421190.051
regulation of peptidase activityGO:0052547960.051
divalent inorganic cation transportGO:00725111780.050
regulation of growth of symbiont in hostGO:0044126190.050
negative regulation of multi organism processGO:0043901680.049
organelle fissionGO:00482851700.049
negative regulation of molecular functionGO:00440922580.048
Human
epithelial cell proliferationGO:00506731740.047
phospholipid catabolic processGO:000939550.046
calcium ion transportGO:00068161590.045
locomotory behaviorGO:00076261950.044
engulfment of apoptotic cellGO:004365230.044
lipid storageGO:0019915360.043
adaptive immune responseGO:00022501550.043
regulation of intracellular protein transportGO:0033157820.042
cation transportGO:00068123990.041
maintenance of locationGO:0051235890.041
sulfur compound metabolic processGO:00067901000.041
membrane invaginationGO:0010324170.040
cytoplasmic transportGO:00164822340.040
action potentialGO:0001508780.040
glycerolipid biosynthetic processGO:0045017500.039
glycerolipid metabolic processGO:00464861220.039
immune response regulating signaling pathwayGO:00027641250.039
cellular homeostasisGO:00197252400.038
sterol transportGO:0015918380.038
regulation of protein processingGO:0070613960.038
regulation of mitotic cell cycle phase transitionGO:1901990730.037
neuron apoptotic processGO:00514021420.037
regulation of neuron apoptotic processGO:00435231220.036
regulation of protein maturationGO:1903317960.036
regulation of cell activationGO:00508652890.036
positive regulation of phagocytosis engulfmentGO:006010030.035
regulation of phosphatidylcholine catabolic processGO:001089920.035
cellular chemical homeostasisGO:00550822150.034
negative regulation of proteolysisGO:0045861740.034
regulation of secretionGO:00510462740.034
cellular protein complex assemblyGO:00436231160.034
sphingolipid biosynthetic processGO:0030148260.034
Human
negative regulation of cellular component organizationGO:00511291940.033
negative regulation of neuron deathGO:1901215980.033
peptidyl tyrosine modificationGO:00182121450.033
organic hydroxy compound metabolic processGO:19016152030.033
Human
epithelial cell migrationGO:0010631630.033
sphingolipid catabolic processGO:003014970.033
Human
negative regulation of cellular amino acid metabolic processGO:004576300.033
progesterone metabolic processGO:004244840.032
protein maturationGO:00516041760.032
cytosolic calcium ion homeostasisGO:0051480700.032
cholesterol transportGO:0030301380.032
golgi to endosome transportGO:000689530.032
metal ion homeostasisGO:00550651890.031
cellular response to lipopolysaccharideGO:0071222770.031
apoptotic signaling pathwayGO:00971903060.031
regulation of multi organism processGO:00439001110.031
steroid metabolic processGO:00082021190.031
growth involved in symbiotic interactionGO:0044110230.031
regulation of homeostatic processGO:00328441820.031
skeletal system developmentGO:00015013560.031
developmental maturationGO:00217001930.030
protein catabolic processGO:00301632210.030
sterol transmembrane transportGO:003538220.030
carbohydrate catabolic processGO:0016052320.030
nuclear divisionGO:00002801580.030
multicellular organismal agingGO:0010259240.029
cell fate commitmentGO:00451652100.029
response to molecule of bacterial originGO:00022371430.029
regulation of transferase activityGO:00513382630.029
Human
morphogenesis of a branching epitheliumGO:00611381930.029
regulation of ion transportGO:00432692150.029
wound healingGO:00420601570.029
regulation of endocytosisGO:0030100690.028
cellular response to lipidGO:00713961450.028
cytokine biosynthetic processGO:0042089680.028
regulation of lipid metabolic processGO:00192161180.028
acylglycerol biosynthetic processGO:0046463180.028
regulation of lipid catabolic processGO:0050994150.028
positive regulation of cellular amine metabolic processGO:003324050.028
oligosaccharide catabolic processGO:000931320.028
regulation of neuron deathGO:19012141340.027
negative regulation of protein maturationGO:1903318790.027
regulation of reactive oxygen species metabolic processGO:2000377400.027
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.027
sequestering of calcium ionGO:0051208180.026
multi organism reproductive behaviorGO:0044705290.026
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.026
anion transportGO:00068201770.026
male gamete generationGO:00482322850.026
fatty acid elongation saturated fatty acidGO:001936710.026
germ cell developmentGO:00072811850.026
regulation of hydrolase activityGO:00513362460.026
cell recognitionGO:0008037830.026
tumor necrosis factor productionGO:0032640500.026
phospholipid metabolic processGO:0006644870.026
tissue homeostasisGO:00018941150.026
positive regulation of cellular amino acid metabolic processGO:004576430.025
macromolecular complex remodelingGO:003436760.025
negative regulation of protein processingGO:0010955790.025
plasma cell differentiationGO:000231730.025
positive regulation of hydrolase activityGO:00513451480.025
multi organism behaviorGO:0051705620.024
heterocycle catabolic processGO:00467002800.024
meiotic cell cycleGO:00513211220.024
reproductive behaviorGO:0019098320.024
hematopoietic progenitor cell differentiationGO:00022441430.024
lateral inhibitionGO:004633110.024
i kappab kinase nf kappab signalingGO:0007249850.024
mapk cascadeGO:00001652810.024
Human
sensory system developmentGO:004888030.024
positive regulation of mapk cascadeGO:00434101700.024
sensory perception of soundGO:0007605970.023
negative regulation of growth of symbiont involved in interaction with hostGO:0044146190.023
skin developmentGO:00435882200.023
nuclear transportGO:00511691390.023
positive regulation of programmed cell deathGO:00430682180.023
necrotic cell deathGO:0070265300.022
intracellular protein transportGO:00068862040.022
membrane organizationGO:00610242450.022
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.022
vesicle organizationGO:0016050600.022
fatty acid elongation unsaturated fatty acidGO:001936820.022
regulation of cell migrationGO:00303342190.022
neuron deathGO:00709971540.022
response to organic cyclic compoundGO:00140701980.022
nuclear importGO:0051170950.022
positive regulation of cytosolic calcium ion concentrationGO:0007204650.022
negative regulation of protein metabolic processGO:00512482820.022
Human
positive regulation of protein phosphorylationGO:00019342420.022
negative regulation of growth of symbiont in hostGO:0044130190.022
cellular response to oxidative stressGO:0034599760.022
regulation of cell cycleGO:00517262810.022
retina development in camera type eyeGO:00600411190.021
regulation of hormone levelsGO:00108172110.021
positive regulation of erk1 and erk2 cascadeGO:0070374470.021
organism emergence from protective structureGO:007168440.021
camera type eye developmentGO:00430102660.021
regulation of nucleocytoplasmic transportGO:0046822730.021
cholesterol storageGO:001087840.021
regulation of defense responseGO:00313472330.021
organic hydroxy compound transportGO:0015850930.021
epithelium migrationGO:0090132630.021
lipid homeostasisGO:0055088630.021
regulation of cytoplasmic transportGO:19036491120.021
regulation of calcium ion transport into cytosolGO:0010522310.021
regulation of cellular catabolic processGO:00313292420.021
neuronal action potentialGO:0019228540.021
negative regulation of apoptotic signaling pathwayGO:20012341040.020
acylglycerol metabolic processGO:0006639550.020
response to light stimulusGO:00094161350.020
organophosphate ester transportGO:0015748280.020
response to lipopolysaccharideGO:00324961280.020
regulation of t cell activationGO:00508631700.020
calcium ion homeostasisGO:00550741270.020
positive regulation of epithelial cell proliferationGO:0050679680.020
regulation of mapk cascadeGO:00434082480.020
Human
response to radiationGO:00093141650.020
cellular response to molecule of bacterial originGO:0071219830.020
leukocyte differentiationGO:00025213420.019
neuron projection extensionGO:1990138640.019
single organism nuclear importGO:1902593950.019
regulation of apoptotic signaling pathwayGO:20012331970.019
regulation of metal ion transportGO:00109591060.019
posttranscriptional regulation of gene expressionGO:00106081550.019
regulation of endopeptidase activityGO:0052548890.019
negative regulation of hydrolase activityGO:0051346710.019
sterol homeostasisGO:0055092450.019
inorganic cation transmembrane transportGO:00986622070.019
response to acid chemicalGO:00011011110.019
multicellular organismal signalingGO:0035637910.018
cellular response to bacterial lipopeptideGO:007122130.018
regulation of vesicle mediated transportGO:00606271390.018
regulation of t cell proliferationGO:0042129920.018
organophosphate catabolic processGO:00464342320.018
nucleocytoplasmic transportGO:00069131390.018
regulation of protein targetingGO:1903533610.018
positive regulation of cell deathGO:00109422240.018
regulation of peptidyl tyrosine phosphorylationGO:0050730930.018
organelle assemblyGO:00709251770.018
carbohydrate metabolic processGO:00059752300.018
hormone metabolic processGO:0042445860.018
blood vessel morphogenesisGO:00485142850.018
cellular response to biotic stimulusGO:0071216920.017
regulation of plasma lipoprotein particle levelsGO:0097006230.017
water soluble vitamin metabolic processGO:0006767100.017
regulation of establishment of protein localizationGO:00702011810.017
regulation of erk1 and erk2 cascadeGO:0070372710.017
lateral line system developmentGO:004892510.017
negative regulation of vesicle fusionGO:003133910.017
triglyceride biosynthetic processGO:0019432170.017
sterol importGO:003537620.017
dna recombinationGO:0006310920.017
striated muscle tissue developmentGO:00147062930.017
cellular divalent inorganic cation homeostasisGO:00725031270.017
protein import into nucleusGO:0006606950.017
regulation of epithelial cell proliferationGO:00506781410.017
regulation of body fluid levelsGO:00508781620.017
tissue regenerationGO:0042246220.017
monosaccharide metabolic processGO:00059961060.017
protein processingGO:00164851630.016
male sex differentiationGO:00466611090.016
angiogenesisGO:00015252010.016
protein importGO:00170381010.016
positive regulation of proteolysisGO:0045862850.016
alcohol catabolic processGO:0046164160.016
striated muscle cell developmentGO:00550021250.016
renal system processGO:0003014480.016
response to bacterial lipoproteinGO:003249340.016
skeletal muscle organ developmentGO:00605381630.016
epidermis developmentGO:00085441870.016
membrane lipid catabolic processGO:004646680.016
Human
kidney developmentGO:00018222130.016
regulation of cellular response to oxidative stressGO:1900407190.015
regulation of calcium ion transportGO:0051924690.015
sequestering of metal ionGO:0051238190.015
spermatogenesisGO:00072832840.015
alcohol metabolic processGO:00060661160.015
Human
negative regulation of phosphorus metabolic processGO:00105631840.015
Human
activation of mapk activity involved in innate immune responseGO:003541920.015
negative regulation of inflammatory responseGO:0050728610.015
negative regulation of protein localization to nucleusGO:1900181230.015
multicellular organismal homeostasisGO:00488711640.015
organic acid transportGO:00158491010.015
hexose metabolic processGO:0019318980.015
regulation of phospholipid catabolic processGO:006069620.015
fertilizationGO:00095661270.015
regulation of transmembrane transportGO:00347621280.015
sensory perception of mechanical stimulusGO:00509541070.015
cellular response to growth factor stimulusGO:00713631970.015
negative regulation of cellular amine metabolic processGO:003323910.015
cell divisionGO:00513011200.015
oogenesisGO:0048477560.015
adult locomotory behaviorGO:0008344910.015
protein localization to organelleGO:00333651850.015
inflammatory response to antigenic stimulusGO:0002437300.015
sterol metabolic processGO:0016125580.015
positive regulation of interleukin 6 productionGO:0032755370.015
microtubule based processGO:00070172360.014
cell maturationGO:00484691270.014
negative regulation of phosphate metabolic processGO:00459361840.014
Human
gonad developmentGO:00084061410.014
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.014
glycerophospholipid catabolic processGO:004647550.014
carbohydrate derivative catabolic processGO:19011362310.014
Human
renal system developmentGO:00720012250.014
organic acid catabolic processGO:0016054510.014
divalent metal ion transportGO:00708381720.014
adult behaviorGO:00305341350.014
organonitrogen compound biosynthetic processGO:19015661920.014
Human
transmission of nerve impulseGO:0019226760.014
female gamete generationGO:0007292740.014
ketone catabolic processGO:004218230.014
hatchingGO:003518840.014
regulation of cell cycle processGO:00105641600.014
sensory perceptionGO:00076002450.014
body fluid secretionGO:0007589530.014
amide transportGO:00428861380.014
negative regulation of neuron apoptotic processGO:0043524920.014
muscle cell developmentGO:00550011330.014
negative regulation of gene silencingGO:006096920.014
regulation of reproductive processGO:2000241660.013
cell growthGO:00160491300.013
blastocyst developmentGO:0001824800.013
interleukin 6 productionGO:0032635580.013
Human
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.013
regulation of ion transmembrane transportGO:00347651190.013
lymphocyte homeostasisGO:0002260640.013
cellular protein catabolic processGO:00442571550.013
regulation of cell shapeGO:0008360390.013
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.013
sensory organ morphogenesisGO:00905962420.013
neuromuscular processGO:0050905990.013
release of sequestered calcium ion into cytosolGO:0051209420.013
positive regulation of cell motilityGO:20001471160.013
lymphocyte differentiationGO:00300982420.013
embryonic organ morphogenesisGO:00485622760.013
notch signaling pathwayGO:0007219710.013
regulation of tumor necrosis factor productionGO:0032680490.013
regulation of inflammatory response to antigenic stimulusGO:0002861210.012
positive regulation of peptidase activityGO:0010952490.012
regulation of mitotic cell cycleGO:00073461260.012
cytosolic calcium ion transportGO:0060401480.012
positive regulation of lamellipodium organizationGO:190274530.012
regulation of neuron projection developmentGO:00109751690.012
transcription factor import into nucleusGO:0042991260.012
antigen processing and presentation of exogenous antigenGO:0019884260.012
regulation of lymphocyte activationGO:00512492400.012
respiratory tube developmentGO:00303231670.012
positive regulation of apoptotic processGO:00430652170.012
immune response activating signal transductionGO:00027571160.012
l ascorbic acid metabolic processGO:001985240.012
myotube cell developmentGO:0014904600.012
amino acid transportGO:0006865610.012
positive regulation of interleukin 12 productionGO:0032735210.012
cholesterol importGO:007050820.012
pigmentationGO:0043473710.012
cellular response to abiotic stimulusGO:0071214560.012
plasma lipoprotein particle clearanceGO:0034381130.012
lung developmentGO:00303241640.012
anatomical structure homeostasisGO:00602491450.012
leukocyte mediated immunityGO:00024431740.012
multicellular organismal reproductive behaviorGO:0033057230.012
peptide transportGO:00158331330.012
mitotic recombinationGO:000631230.012
sphingosine metabolic processGO:000667040.012
Human
positive regulation of cellular component biogenesisGO:0044089940.012
axonogenesisGO:00074092740.012
actin filament branchingGO:009013510.012
glycolipid catabolic processGO:001937750.012
Human
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.012
regulation of chemotaxisGO:0050920530.012
myelinationGO:0042552740.012
male gonad developmentGO:0008584880.012
regulation of protein import into nucleusGO:0042306520.012
glycolipid metabolic processGO:0006664250.011
Human
negative regulation of endopeptidase activityGO:0010951440.011
carboxylic acid catabolic processGO:0046395510.011
epithelial tube morphogenesisGO:00605623030.011
positive regulation of transferase activityGO:00513471670.011
bone developmentGO:00603481200.011
regulation of synaptic growth at neuromuscular junctionGO:000858240.011
endocrine processGO:0050886390.011
cellular response to cytokine stimulusGO:00713451890.011
Human
establishment of protein localization to organelleGO:00725941180.011
cell type specific apoptotic processGO:00972852680.011
regulation of protein complex assemblyGO:0043254830.011
regulation of protein serine threonine kinase activityGO:00719001570.011
Human
extracellular matrix organizationGO:00301981470.011
morphogenesis of a branching structureGO:00017632030.011
circadian rhythmGO:00076231140.011
regulation of chromatin silencingGO:003193520.011
proteolysis involved in cellular protein catabolic processGO:00516031470.011
response to inorganic substanceGO:0010035960.011
protein localization to nucleusGO:00345041210.011
negative regulation of transcription factor import into nucleusGO:0042992130.011
chemotaxisGO:00069352470.011
autophagic vacuole fusionGO:000004610.011
response to oxidative stressGO:00069791230.011
carbohydrate homeostasisGO:00335001280.011
development of primary sexual characteristicsGO:00451371430.011
cellular ion homeostasisGO:00068731650.011
determination of left right symmetryGO:0007368800.011
regulation of arp2 3 complex mediated actin nucleationGO:003431510.011
positive regulation of cell cycleGO:0045787920.011
hydrogen transportGO:0006818350.011
autophagyGO:0006914450.011
small molecule biosynthetic processGO:00442831320.011
Human
cholesterol homeostasisGO:0042632440.010
positive regulation of antimicrobial peptide productionGO:000222510.010
extracellular structure organizationGO:00430621480.010
regulation of wnt signaling pathwayGO:00301111230.010
meiotic cell cycle processGO:1903046770.010
cellular metal ion homeostasisGO:00068751510.010
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.010
positive regulation of protein modification processGO:00314012990.010
Human
myeloid leukocyte differentiationGO:00025731190.010
visual behaviorGO:0007632450.010
cellular response to thyroid hormone stimulusGO:009706710.010
regulation of interleukin 12 productionGO:0032655300.010
water soluble vitamin biosynthetic processGO:004236430.010
positive regulation of macrophage derived foam cell differentiationGO:001074440.010
positive regulation of secretionGO:00510471300.010
symbiosis encompassing mutualism through parasitismGO:0044403830.010
regulation of protein secretionGO:0050708820.010
humoral immune responseGO:0006959570.010

Gba disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.777
Human
lipid storage diseaseDOID:945500.777
Human
inherited metabolic disorderDOID:65500.777
Human
lysosomal storage diseaseDOID:321100.777
Human
disease of anatomical entityDOID:700.435
Human
nervous system diseaseDOID:86300.435
Human
central nervous system diseaseDOID:33100.435
Human
brain diseaseDOID:93600.266
sphingolipidosisDOID:192700.226
Human
variable age at onset electroclinical syndromeDOID:005070600.196
electroclinical syndromeDOID:005070100.196
epilepsy syndromeDOID:182600.196
progressive myoclonus epilepsyDOID:89100.070
lymphatic system diseaseDOID:7500.041
immune system diseaseDOID:291400.041
neuronal ceroid lipofuscinosisDOID:1450300.033
musculoskeletal system diseaseDOID:1700.032
connective tissue diseaseDOID:6500.032
cerebral degenerationDOID:144300.026
neurodegenerative diseaseDOID:128900.017
Human
integumentary system diseaseDOID:1600.014
osteopetrosisDOID:1353300.012
osteosclerosisDOID:425400.012
bone remodeling diseaseDOID:008000500.012
bone diseaseDOID:008000100.012