Mus musculus

43 known processes

Acsl4

acyl-CoA synthetase long-chain family member 4

(Aliases: ACS4,Facl4,Lacs4,AU018108,9430020A05Rik)

Acsl4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
vesicle organizationGO:0016050600.164
maintenance of locationGO:0051235890.150
Fly
regulation of secretionGO:00510462740.148
Human
aromatic compound catabolic processGO:00194392860.146
nucleoside triphosphate metabolic processGO:00091412300.141
anion transportGO:00068201770.136
Human Rat
cation transportGO:00068123990.135
nucleoside phosphate metabolic processGO:00067533380.133
nucleobase containing small molecule metabolic processGO:00550863520.126
regionalizationGO:00030023370.124
Zebrafish Fly
membrane organizationGO:00610242450.122
ribonucleoside metabolic processGO:00091192450.118
protein catabolic processGO:00301632210.112
lipid transportGO:0006869980.112
Human Rat
purine nucleotide metabolic processGO:00061633020.106
cellular response to topologically incorrect proteinGO:0035967250.106
membrane fusionGO:0061025380.102
sphingolipid metabolic processGO:0006665450.102
purine ribonucleoside triphosphate catabolic processGO:00092071990.100
synaptic transmissionGO:00072683290.097
Fly
amine metabolic processGO:0009308450.093
nucleotide catabolic processGO:00091662170.092
establishment of vesicle localizationGO:0051650810.091
regulation of membrane potentialGO:00423911920.089
cellular amino acid metabolic processGO:00065201030.086
nucleoside triphosphate catabolic processGO:00091432050.084
ribonucleoside triphosphate metabolic processGO:00091992200.084
purine ribonucleoside metabolic processGO:00461282410.083
nucleoside phosphate catabolic processGO:19012922220.081
purine nucleoside metabolic processGO:00422782410.079
nucleoside catabolic processGO:00091642060.079
cellular response to arsenic containing substanceGO:007124340.078
gtp catabolic processGO:00061841430.077
regulation of neuron differentiationGO:00456642810.075
actin filament organizationGO:00070151130.075
purine ribonucleotide metabolic processGO:00091502900.075
organophosphate catabolic processGO:00464342320.074
regulation of cell projection organizationGO:00313442060.073
establishment of organelle localizationGO:00516561220.073
nitrogen compound transportGO:00717052710.072
purine containing compound metabolic processGO:00725213110.072
metal ion homeostasisGO:00550651890.070
cytoplasmic transportGO:00164822340.068
Fly
organelle localizationGO:00516401790.068
neuronal action potentialGO:0019228540.067
cellular amine metabolic processGO:0044106440.067
ribonucleoside triphosphate catabolic processGO:00092031990.066
cellular ion homeostasisGO:00068731650.065
negative regulation of protein metabolic processGO:00512482820.064
regulation of defense responseGO:00313472330.064
cellular lipid metabolic processGO:00442553230.064
leukocyte differentiationGO:00025213420.064
inflammatory responseGO:00069542440.064
purine ribonucleotide catabolic processGO:00091542080.063
cellular chemical homeostasisGO:00550822150.063
cation homeostasisGO:00550802120.062
response to endoplasmic reticulum stressGO:0034976530.061
cellular homeostasisGO:00197252400.061
purine nucleoside triphosphate metabolic processGO:00091442260.060
ribonucleotide metabolic processGO:00092592910.060
membrane lipid metabolic processGO:0006643530.059
purine containing compound catabolic processGO:00725232130.058
nucleotide metabolic processGO:00091173320.058
guanosine containing compound metabolic processGO:19010681440.058
positive regulation of nervous system developmentGO:00519622210.057
ribose phosphate metabolic processGO:00196932910.057
nucleoside metabolic processGO:00091162460.056
nucleoside monophosphate metabolic processGO:0009123850.055
cellularizationGO:000734910.054
establishment or maintenance of cell polarityGO:0007163860.053
lipid localizationGO:00108761260.053
Human Rat Fly
purine nucleotide catabolic processGO:00061952110.052
organonitrogen compound catabolic processGO:19015652640.052
proteolysis involved in cellular protein catabolic processGO:00516031470.052
purine nucleoside catabolic processGO:00061522050.051
regulation of cellular ketone metabolic processGO:0010565660.051
glycosyl compound metabolic processGO:19016572460.049
regulation of establishment of protein localizationGO:00702011810.049
purine nucleoside triphosphate catabolic processGO:00091462030.048
cellular metal ion homeostasisGO:00068751510.048
organic acid transportGO:00158491010.048
Human Rat
regulation of cytokine productionGO:00018172660.048
positive regulation of cell developmentGO:00107202370.048
positive regulation of secretionGO:00510471300.047
action potentialGO:0001508780.047
response to organonitrogen compoundGO:00102432460.047
positive regulation of cell projection organizationGO:0031346950.047
regulation of cellular amine metabolic processGO:0033238200.046
endomembrane system organizationGO:00102561470.046
mitochondrion distributionGO:004831140.046
carbohydrate homeostasisGO:00335001280.046
regulation of cellular amino acid metabolic processGO:000652150.046
cellular protein catabolic processGO:00442571550.045
organic anion transportGO:00157111370.045
Human Rat
carbohydrate derivative biosynthetic processGO:19011371830.043
regulation of synaptic growth at neuromuscular junctionGO:000858240.042
Fly
protein localization to organelleGO:00333651850.042
positive regulation of secretion by cellGO:19035321140.042
oxidation reduction processGO:00551143420.042
regulation of secretion by cellGO:19035302490.041
actin polymerization or depolymerizationGO:0008154540.041
purine ribonucleoside triphosphate metabolic processGO:00092052200.040
transmission of nerve impulseGO:0019226760.040
regulation of neuron projection developmentGO:00109751690.039
regulation of homeostatic processGO:00328441820.039
carbohydrate derivative catabolic processGO:19011362310.039
mapk cascadeGO:00001652810.038
Zebrafish
actin cytoskeleton organizationGO:00300362200.038
positive regulation of neuron differentiationGO:00456661410.038
regulation of neuron apoptotic processGO:00435231220.037
modification dependent macromolecule catabolic processGO:00436321330.037
carbohydrate metabolic processGO:00059752300.037
guanosine containing compound catabolic processGO:19010691440.037
cytokine productionGO:00018163190.036
positive regulation of neuron projection developmentGO:0010976790.036
multicellular organismal signalingGO:0035637910.036
calcium ion homeostasisGO:00550741270.036
cellular response to organonitrogen compoundGO:00714171450.036
positive regulation of cellular amino acid metabolic processGO:004576430.036
neurotransmitter transportGO:0006836760.036
lipid biosynthetic processGO:00086101790.035
Human
ubiquitin dependent protein catabolic processGO:00065111290.035
regulation of cellular catabolic processGO:00313292420.034
transmembrane transportGO:00550854120.034
cellular calcium ion homeostasisGO:00068741190.033
regulation of hormone levelsGO:00108172110.033
fertilizationGO:00095661270.033
glucose homeostasisGO:00425931280.033
regulation of cellular response to stressGO:00801351590.033
Zebrafish
organophosphate ester transportGO:0015748280.033
peptidyl amino acid modificationGO:00181933360.032
organic cyclic compound catabolic processGO:19013612950.031
divalent metal ion transportGO:00708381720.031
compound eye developmentGO:004874910.031
protein ubiquitinationGO:00165671710.031
regulation of cellular component sizeGO:00325351210.031
regulation of mapk cascadeGO:00434082480.031
Zebrafish
establishment of synaptic vesicle localizationGO:0097480570.031
regulation of apoptotic signaling pathwayGO:20012331970.030
microtubule based movementGO:0007018840.030
learning or memoryGO:00076111480.030
negative regulation of phosphorus metabolic processGO:00105631840.030
connective tissue replacement involved in inflammatory response wound healingGO:000224830.029
ribonucleoside monophosphate metabolic processGO:0009161800.029
intracellular protein transportGO:00068862040.029
neuron deathGO:00709971540.029
interleukin 8 secretionGO:007260630.029
cellular divalent inorganic cation homeostasisGO:00725031270.029
establishment of protein localization to organelleGO:00725941180.029
cellular response to oxidative stressGO:0034599760.028
muscle cell differentiationGO:00426922610.028
defense response to other organismGO:00985421970.028
purine ribonucleoside catabolic processGO:00461302050.028
positive regulation of cellular amine metabolic processGO:003324050.027
cellular ketone metabolic processGO:0042180840.027
peptide metabolic processGO:0006518460.026
small molecule biosynthetic processGO:00442831320.026
negative regulation of phosphate metabolic processGO:00459361840.026
phospholipid translocationGO:004533290.026
regulation of protein secretionGO:0050708820.026
single organism cell adhesionGO:00986021560.026
cellular response to growth factor stimulusGO:00713631970.025
ribonucleoside catabolic processGO:00424542060.025
divalent inorganic cation homeostasisGO:00725071380.025
cognitionGO:00508901490.025
lateral inhibitionGO:004633110.025
response to oxidative stressGO:00069791230.025
response to nutrient levelsGO:00316671090.025
Rat
calcium ion transportGO:00068161590.025
protein processingGO:00164851630.024
vesicle localizationGO:0051648860.024
peptidyl tyrosine phosphorylationGO:00181081430.024
inorganic ion transmembrane transportGO:00986602340.024
homeostasis of number of cellsGO:00488722100.024
gtp metabolic processGO:00460391440.024
regulation of cell migrationGO:00303342190.024
regulation of anatomical structure sizeGO:00900661780.024
neurotransmitter secretionGO:0007269620.024
regulation of transferase activityGO:00513382630.024
ion transmembrane transportGO:00342203610.024
organonitrogen compound biosynthetic processGO:19015661920.024
regulation of cellular component biogenesisGO:00440871810.023
Fly
cellular macromolecule catabolic processGO:00442652060.023
neuron apoptotic processGO:00514021420.023
translationGO:0006412930.023
positive regulation of apoptotic signaling pathwayGO:2001235950.023
stem cell differentiationGO:00488632680.023
cellular nitrogen compound catabolic processGO:00442702800.023
protein polymerizationGO:0051258570.023
myelinationGO:0042552740.023
innate immune responseGO:00450871570.023
protein secretionGO:00093061110.023
regulation of protein transportGO:00512231630.023
synaptic vesicle localizationGO:0097479590.022
learningGO:0007612980.022
microtubule based processGO:00070172360.022
er nucleus signaling pathwayGO:0006984270.022
negative regulation of neuron apoptotic processGO:0043524920.022
regulation of cell adhesionGO:00301551540.022
divalent inorganic cation transportGO:00725111780.022
regulation of leukocyte differentiationGO:19021051590.022
wnt signaling pathwayGO:00160551880.022
regulation of ion transportGO:00432692150.022
Human
regulation of engulfment of apoptotic cellGO:190107420.022
nuclear divisionGO:00002801580.022
rhythmic processGO:00485111740.022
negative regulation of cellular protein metabolic processGO:00322692470.021
negative regulation of intracellular signal transductionGO:19025321670.021
monocarboxylic acid metabolic processGO:00327871910.021
cellular response to lipidGO:00713961450.021
defense response to bacteriumGO:00427421190.021
response to inorganic substanceGO:0010035960.021
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.021
circadian rhythmGO:00076231140.021
negative regulation of neuron deathGO:1901215980.021
t cell activationGO:00421102890.021
protein localization to membraneGO:00726571080.021
mitochondrion organizationGO:00070051340.020
lymphocyte differentiationGO:00300982420.020
macromolecule catabolic processGO:00090572810.020
gland developmentGO:00487323300.020
positive regulation of programmed cell deathGO:00430682180.020
regulation of cytoplasmic translationGO:200076540.020
regulation of neuronal synaptic plasticityGO:0048168300.020
regulation of protein kinase activityGO:00458592320.020
glycoprotein metabolic processGO:00091001160.020
fat cell differentiationGO:00454441600.020
cellular protein complex assemblyGO:00436231160.020
positive regulation of hormone secretionGO:0046887380.020
mrna processingGO:0006397630.020
cell growthGO:00160491300.020
Human
endoplasmic reticulum unfolded protein responseGO:0030968190.019
response to acid chemicalGO:00011011110.019
ribonucleotide catabolic processGO:00092612080.019
myotube differentiationGO:00149021050.019
cell adhesionGO:00071553290.019
cellular response to biotic stimulusGO:0071216920.019
regulation of lymphocyte activationGO:00512492400.019
immune effector processGO:00022523210.019
cell type specific apoptotic processGO:00972852680.019
interleukin 8 productionGO:003263740.019
positive regulation of protein phosphorylationGO:00019342420.019
regulation of cell motilityGO:20001452360.019
establishment of protein localization to membraneGO:0090150540.019
muscle system processGO:00030121410.019
respiratory system developmentGO:00605411900.019
purine ribonucleoside monophosphate metabolic processGO:0009167800.019
axon ensheathmentGO:0008366760.018
regulation of cytoplasmic transportGO:19036491120.018
glycerolipid metabolic processGO:00464861220.018
Rat
modification dependent protein catabolic processGO:00199411330.018
apoptotic signaling pathwayGO:00971903060.018
vesicle fusionGO:0006906160.018
response to radiationGO:00093141650.018
angiogenesisGO:00015252010.018
myeloid leukocyte differentiationGO:00025731190.018
negative regulation of phosphorylationGO:00423261660.018
axonogenesisGO:00074092740.018
Fly
positive regulation of insulin secretionGO:0032024260.018
positive regulation of protein transportGO:0051222930.018
insulin processingGO:003007020.017
regulation of inflammatory responseGO:00507271470.017
multi multicellular organism processGO:00447061090.017
response to peptideGO:19016521360.017
regulation of response to woundingGO:19030341890.017
cell recognitionGO:0008037830.017
establishment or maintenance of cytoskeleton polarityGO:003095220.017
inorganic cation transmembrane transportGO:00986622070.017
actin filament polymerizationGO:0030041440.017
regulation of organelle organizationGO:00330432890.017
regulation of cell activationGO:00508652890.017
cell substrate adhesionGO:00315891300.017
regulation of multi organism processGO:00439001110.017
post mating behaviorGO:004529730.017
regulation of kinase activityGO:00435492490.017
establishment of melanosome localizationGO:0032401110.017
positive regulation of cytosolic calcium ion concentrationGO:0007204650.016
positive regulation of macroautophagyGO:001623930.016
asymmetric stem cell divisionGO:009872230.016
organophosphate biosynthetic processGO:00904071220.016
posttranscriptional regulation of gene expressionGO:00106081550.016
spermatid developmentGO:00072861080.016
regulation of cell growthGO:0001558910.016
Human
positive regulation of cell motilityGO:20001471160.016
germ cell developmentGO:00072811850.016
t cell differentiationGO:00302171740.016
hormone metabolic processGO:0042445860.016
regulation of neurotransmitter levelsGO:0001505870.016
skeletal muscle fiber developmentGO:0048741580.016
positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathwayGO:190223730.016
sperm egg recognitionGO:0035036370.016
positive regulation of protein modification processGO:00314012990.016
positive regulation of cellular catabolic processGO:00313311480.015
response to lipopolysaccharideGO:00324961280.015
peptide secretionGO:00027901140.015
post golgi vesicle mediated transportGO:0006892130.015
response to organic cyclic compoundGO:00140701980.015
leukocyte homeostasisGO:0001776790.015
asymmetric neuroblast divisionGO:005505910.015
protein targetingGO:00066051430.015
positive regulation of cell deathGO:00109422240.015
morphogenesis of embryonic epitheliumGO:00163311590.015
meiotic cell cycleGO:00513211220.015
cellular amide metabolic processGO:0043603580.015
cell cell recognitionGO:0009988440.015
regulation of protein localizationGO:00328802310.015
neuron projection extensionGO:1990138640.015
myeloid cell differentiationGO:00300992330.015
ensheathment of neuronsGO:0007272760.015
blood vessel morphogenesisGO:00485142850.015
peptide hormone secretionGO:00300721090.015
protein targeting to vacuoleGO:000662330.015
regulation of synaptic plasticityGO:0048167870.015
muscle tissue developmentGO:00605373080.015
cellular response to cytokine stimulusGO:00713451890.015
male gamete generationGO:00482322850.015
forebrain developmentGO:00309003020.015
endoplasmic reticulum tubular network organizationGO:007178610.015
regulation of peptide transportGO:0090087910.015
striated muscle tissue developmentGO:00147062930.015
regulation of intracellular transportGO:00323861590.015
regulation of peptide secretionGO:0002791770.014
carboxylic acid transportGO:00469421000.014
Human Rat
cellular response to dna damage stimulusGO:00069742070.014
b cell activationGO:00421131610.014
peptide transportGO:00158331330.014
cell chemotaxisGO:0060326810.014
sodium ion transportGO:0006814730.014
multicellular organismal homeostasisGO:00488711640.014
amide transportGO:00428861380.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.014
Zebrafish Fly
glycosyl compound catabolic processGO:19016582060.014
canonical wnt signaling pathwayGO:00600701300.014
response to transforming growth factor betaGO:0071559880.014
cellular response to peptide hormone stimulusGO:0071375920.014
extracellular matrix organizationGO:00301981470.014
organic hydroxy compound transportGO:0015850930.014
hormone secretionGO:00468791280.013
cellular response to hormone stimulusGO:00328701500.013
protein localization to plasma membraneGO:0072659570.013
negative regulation of immune system processGO:00026832090.013
regulation of peptide hormone secretionGO:0090276750.013
regulation of system processGO:00440572000.013
regulation of gtp catabolic processGO:00331241130.013
nucleotide biosynthetic processGO:0009165780.013
single fertilizationGO:0007338820.013
tissue homeostasisGO:00018941150.013
regulation of protein complex assemblyGO:0043254830.013
heterocycle catabolic processGO:00467002800.013
regulation of lymphocyte differentiationGO:00456191070.013
endocytosisGO:00068971680.013
transition metal ion homeostasisGO:0055076540.013
organic hydroxy compound metabolic processGO:19016152030.013
cellular biogenic amine metabolic processGO:0006576280.013
negative regulation of translationGO:0017148220.013
positive regulation of protein secretionGO:0050714520.013
clathrin mediated endocytosisGO:007258370.013
lymphocyte activation involved in immune responseGO:0002285930.013
response to insulinGO:00328681000.013
regulation of nucleotide metabolic processGO:00061401690.013
response to light stimulusGO:00094161350.013
binding of sperm to zona pellucidaGO:0007339340.013
protein localization to vacuoleGO:007266540.012
synapse organizationGO:00508081250.012
Fly
localization within membraneGO:005166840.012
mrna metabolic processGO:0016071840.012
regulation of t cell activationGO:00508631700.012
prevention of polyspermyGO:006046840.012
positive regulation of growthGO:00459271040.012
Human
cellular modified amino acid metabolic processGO:0006575630.012
cellular response to starvationGO:0009267570.012
g protein coupled receptor signaling pathwayGO:00071862430.012
rna processingGO:00063961050.012
locomotory behaviorGO:00076261950.012
negative regulation of molecular functionGO:00440922580.012
cytokinetic processGO:003250620.012
response to molecule of bacterial originGO:00022371430.012
developmental cell growthGO:0048588840.012
cellular response to nutrient levelsGO:0031669640.012
skeletal system developmentGO:00015013560.012
myeloid cell homeostasisGO:00022621140.012
exocytosisGO:00068871210.012
phospholipid transportGO:0015914210.012
regulation of neuron deathGO:19012141340.012
regulation of cellular carbohydrate metabolic processGO:0010675750.012
sequestering of metal ionGO:0051238190.012
circulatory system processGO:00030131970.012
developmental growth involved in morphogenesisGO:00605601380.012
response to metal ionGO:0010038470.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.012
positive regulation of cell activationGO:00508671580.011
cellular response to acid chemicalGO:0071229680.011
small gtpase mediated signal transductionGO:0007264970.011
alcohol metabolic processGO:00060661160.011
cation transmembrane transportGO:00986552660.011
proteasomal protein catabolic processGO:0010498980.011
intracellular cholesterol transportGO:003236730.011
skeletal muscle organ developmentGO:00605381630.011
amino acid transportGO:0006865610.011
regulation of protein catabolic processGO:00421761080.011
neural precursor cell proliferationGO:00613511210.011
lung developmentGO:00303241640.011
synaptic vesicle recyclingGO:0036465190.011
nucleocytoplasmic transportGO:00069131390.011
intracellular sterol transportGO:003236630.011
sensory perceptionGO:00076002450.011
histone modificationGO:00165701590.011
negative regulation of t cell activationGO:0050868650.011
negative regulation of defense responseGO:0031348770.011
nuclear importGO:0051170950.011
hydrogen transportGO:0006818350.011
regulation of exocytosisGO:0017157610.011
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.011
protein oligomerizationGO:0051259670.011
developmental maturationGO:00217001930.011
positive regulation of cytokine productionGO:00018191740.011
cellular response to lipopolysaccharideGO:0071222770.011
response to oxygen levelsGO:0070482620.011
plasma membrane organizationGO:0007009900.011
response to decreased oxygen levelsGO:0036293590.011
pigmentationGO:0043473710.011
establishment of mitochondrion localizationGO:005165440.011
negative regulation of cell proliferationGO:00082852960.011
regulation of circadian rhythmGO:0042752580.011
cellular transition metal ion homeostasisGO:0046916320.011
positive regulation of dna templated transcription elongationGO:003278620.011
retrograde transport endosome to golgiGO:004214720.011
negative regulation of nervous system developmentGO:00519611560.011
Fly
calcium ion transport into cytosolGO:0060402480.011
calcium ion dependent exocytosisGO:0017156350.011
positive regulation of dendrite developmentGO:1900006210.011
interspecies interaction between organismsGO:0044419830.011
lymphocyte mediated immunityGO:00024491390.010
positive regulation of peptide hormone secretionGO:0090277310.010
monosaccharide metabolic processGO:00059961060.010
l amino acid transportGO:0015807320.010
carbohydrate transportGO:0008643620.010
glycerophospholipid metabolic processGO:0006650710.010
regulation of actin filament lengthGO:0030832450.010
dephosphorylationGO:00163111290.010
regulation of ossificationGO:00302781120.010
regulation of nucleoside metabolic processGO:00091181300.010
organelle fissionGO:00482851700.010
positive regulation of defense responseGO:00313491240.010
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:004316230.010
establishment of protein localization to vacuoleGO:007266640.010
intracellular lipid transportGO:003236530.010
cerebellum morphogenesisGO:0021587420.010
negative regulation of synapse assemblyGO:005196430.010
Fly
macromolecule glycosylationGO:0043413550.010
ras protein signal transductionGO:0007265770.010
cellular response to amino acid stimulusGO:0071230290.010
purine nucleoside monophosphate metabolic processGO:0009126810.010
b cell differentiationGO:0030183780.010
respiratory tube developmentGO:00303231670.010
microtubule based transportGO:0010970500.010

Acsl4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.082
sensory system diseaseDOID:005015500.082
retinal diseaseDOID:567900.082
eye and adnexa diseaseDOID:149200.082
retinal degenerationDOID:846600.082
nervous system diseaseDOID:86300.082
eye diseaseDOID:561400.082
inherited metabolic disorderDOID:65500.024
disease of metabolismDOID:001466700.024
neurodegenerative diseaseDOID:128900.018
central nervous system diseaseDOID:33100.018
connective tissue diseaseDOID:6500.014
musculoskeletal system diseaseDOID:1700.014
brain diseaseDOID:93600.011