Mus musculus

41 known processes

Degs1

degenerative spermatocyte homolog 1 (Drosophila)

(Aliases: Mdes,Degs,Des1,AA536663)

Degs1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cation homeostasisGO:00550802120.152
ion transmembrane transportGO:00342203610.146
transmembrane transportGO:00550854120.102
cation transportGO:00068123990.101
anion transportGO:00068201770.100
organic anion transportGO:00157111370.095
inorganic ion transmembrane transportGO:00986602340.086
metal ion homeostasisGO:00550651890.079
cation transmembrane transportGO:00986552660.078
cytokine productionGO:00018163190.076
engulfment of apoptotic cellGO:004365230.075
membrane lipid biosynthetic processGO:0046467320.074
membrane organizationGO:00610242450.070
mapk cascadeGO:00001652810.068
immune effector processGO:00022523210.061
regulation of cytokine productionGO:00018172660.061
organic acid transportGO:00158491010.060
cellular lipid metabolic processGO:00442553230.059
sphingolipid biosynthetic processGO:0030148260.054
endomembrane system organizationGO:00102561470.053
divalent metal ion transportGO:00708381720.051
regulation of homeostatic processGO:00328441820.051
regulation of cell motilityGO:20001452360.049
cellular ion homeostasisGO:00068731650.048
calcium ion homeostasisGO:00550741270.048
lipid transportGO:0006869980.044
regulation of secretionGO:00510462740.043
regulation of angiotensin metabolic processGO:006017740.041
positive regulation of neutrophil apoptotic processGO:003303110.041
cellular amino acid metabolic processGO:00065201030.041
angiogenesisGO:00015252010.040
cellular chemical homeostasisGO:00550822150.040
cell adhesionGO:00071553290.040
amine metabolic processGO:0009308450.039
carboxylic acid transportGO:00469421000.039
positive regulation of programmed cell deathGO:00430682180.037
positive regulation of apoptotic processGO:00430652170.036
nucleobase containing small molecule metabolic processGO:00550863520.036
regulation of protein localizationGO:00328802310.035
cellular homeostasisGO:00197252400.035
leukocyte differentiationGO:00025213420.035
cellular amine metabolic processGO:0044106440.035
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:004316230.034
regulation of organelle organizationGO:00330432890.034
inorganic cation transmembrane transportGO:00986622070.034
nucleoside metabolic processGO:00091162460.034
t cell activationGO:00421102890.033
interleukin 8 secretionGO:007260630.033
cellular metal ion homeostasisGO:00068751510.033
blood vessel morphogenesisGO:00485142850.032
protein processingGO:00164851630.031
hemostasisGO:0007599780.031
lymphocyte differentiationGO:00300982420.031
regulation of mapk cascadeGO:00434082480.031
organic hydroxy compound metabolic processGO:19016152030.030
regulation of vesicle mediated transportGO:00606271390.030
ceramide biosynthetic processGO:0046513200.030
purine ribonucleotide metabolic processGO:00091502900.029
blood coagulationGO:0007596760.029
purine ribonucleotide catabolic processGO:00091542080.028
positive regulation of cellular amino acid metabolic processGO:004576430.028
leukocyte mediated immunityGO:00024431740.028
regulation of membrane potentialGO:00423911920.027
negative regulation of protein metabolic processGO:00512482820.027
regulation of hydrolase activityGO:00513362460.027
tissue remodelingGO:00487711020.027
positive regulation of homeostatic processGO:0032846640.027
response to acid chemicalGO:00011011110.027
calcium ion transportGO:00068161590.027
negative regulation of interleukin 8 secretionGO:200048310.026
apoptotic signaling pathwayGO:00971903060.026
regionalizationGO:00030023370.026
homeostasis of number of cellsGO:00488722100.026
cellular divalent inorganic cation homeostasisGO:00725031270.026
negative regulation of molecular functionGO:00440922580.026
regulation of wnt signaling pathwayGO:00301111230.026
protein localization to membraneGO:00726571080.026
muscle contractionGO:00069361010.026
divalent inorganic cation homeostasisGO:00725071380.025
nucleoside triphosphate metabolic processGO:00091412300.025
nucleoside phosphate metabolic processGO:00067533380.025
organelle assemblyGO:00709251770.025
regulation of cellular ketone metabolic processGO:0010565660.025
protein catabolic processGO:00301632210.024
regulation of neutrophil apoptotic processGO:003302910.024
oxidation reduction processGO:00551143420.024
carbohydrate derivative catabolic processGO:19011362310.024
nucleotide metabolic processGO:00091173320.024
regulation of cellular amine metabolic processGO:0033238200.024
divalent inorganic cation transportGO:00725111780.024
actin polymerization or depolymerizationGO:0008154540.023
establishment or maintenance of cytoskeleton polarityGO:003095220.023
leukocyte homeostasisGO:0001776790.023
lymphocyte mediated immunityGO:00024491390.023
intracellular protein transportGO:00068862040.023
regulation of sequence specific dna binding transcription factor activityGO:00510901060.023
cell cell junction organizationGO:0045216720.022
fibrinolysisGO:004273030.022
regulation of apoptotic signaling pathwayGO:20012331970.022
purine nucleoside metabolic processGO:00422782410.022
mitotic cell cycle processGO:19030471590.022
multi multicellular organism processGO:00447061090.022
positive regulation of cell deathGO:00109422240.022
organophosphate catabolic processGO:00464342320.021
peptidyl amino acid modificationGO:00181933360.021
heterocycle catabolic processGO:00467002800.021
negative regulation of cell proliferationGO:00082852960.021
ameboidal type cell migrationGO:00016671280.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.021
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.021
regulation of cellular amino acid metabolic processGO:000652150.021
regulation of cell migrationGO:00303342190.021
sphingolipid metabolic processGO:0006665450.021
positive regulation of protein modification processGO:00314012990.021
regulation of cell activationGO:00508652890.021
regulation of anatomical structure sizeGO:00900661780.021
cellular ketone metabolic processGO:0042180840.021
muscle system processGO:00030121410.021
ossificationGO:00015032160.021
posttranscriptional regulation of gene expressionGO:00106081550.021
acid secretionGO:0046717330.020
regulation of protein transportGO:00512231630.020
wnt signaling pathwayGO:00160551880.020
regulation of secretion by cellGO:19035302490.020
mitotic cell cycleGO:00002781950.020
b cell activationGO:00421131610.020
positive regulation of cellular amine metabolic processGO:003324050.020
positive regulation of myeloid cell apoptotic processGO:003303440.020
amide transportGO:00428861380.020
mitotic cytokinesisGO:000028140.019
negative regulation of cytokine productionGO:0001818840.019
regulation of cellular component biogenesisGO:00440871810.019
nucleotide catabolic processGO:00091662170.019
regulation of interleukin 8 productionGO:003267730.019
regulation of response to woundingGO:19030341890.019
negative regulation of intracellular signal transductionGO:19025321670.019
skin developmentGO:00435882200.019
adaptive immune responseGO:00022501550.019
phagocytosisGO:0006909660.019
transmission of nerve impulseGO:0019226760.019
cellular calcium ion homeostasisGO:00068741190.019
regulation of ossificationGO:00302781120.019
neutrophil apoptotic processGO:000178130.019
mitochondrion degradationGO:000042230.018
gland developmentGO:00487323300.018
t cell differentiationGO:00302171740.018
regulation of lymphocyte activationGO:00512492400.018
transition metal ion transportGO:0000041380.018
nitrogen compound transportGO:00717052710.018
regulation of muscle contractionGO:0006937490.018
positive regulation of cell adhesionGO:0045785800.017
endocytosisGO:00068971680.017
purine ribonucleoside metabolic processGO:00461282410.017
inflammatory responseGO:00069542440.017
regulation of exocytosisGO:0017157610.017
epithelial tube morphogenesisGO:00605623030.017
cell substrate adhesionGO:00315891300.017
ribonucleotide metabolic processGO:00092592910.017
ribonucleoside triphosphate metabolic processGO:00091992200.017
positive regulation of cell motilityGO:20001471160.017
positive regulation of mapk cascadeGO:00434101700.017
purine nucleotide metabolic processGO:00061633020.017
regulation of interleukin 8 secretionGO:200048220.017
regulation of angiotensin levels in bloodGO:000200240.017
actin filament organizationGO:00070151130.017
monocarboxylic acid transportGO:0015718440.017
aromatic compound catabolic processGO:00194392860.017
regulation of peptidase activityGO:0052547960.017
regulation of cell adhesionGO:00301551540.017
nucleoside catabolic processGO:00091642060.017
skeletal system developmentGO:00015013560.017
positive regulation of apoptotic signaling pathwayGO:2001235950.017
neural tube developmentGO:00219151600.016
regulation of hormone levelsGO:00108172110.016
cellular response to lipidGO:00713961450.016
cellular protein catabolic processGO:00442571550.016
phospholipid metabolic processGO:0006644870.016
carbohydrate metabolic processGO:00059752300.016
exocytosisGO:00068871210.016
macromolecule catabolic processGO:00090572810.016
protein localization to plasma membraneGO:0072659570.016
regulation of epithelial cell proliferationGO:00506781410.016
hormone metabolic processGO:0042445860.016
positive regulation of wnt signaling pathwayGO:0030177450.016
alpha beta t cell differentiationGO:0046632690.016
regulation of hemostasisGO:1900046280.016
plasma membrane organizationGO:0007009900.016
negative regulation of phosphorus metabolic processGO:00105631840.016
regulation of muscle system processGO:0090257800.016
regulation of neuron projection developmentGO:00109751690.016
ribose phosphate metabolic processGO:00196932910.015
ceramide metabolic processGO:0006672310.015
regulation of system processGO:00440572000.015
positive regulation of cytokine productionGO:00018191740.015
cellular nitrogen compound catabolic processGO:00442702800.015
leukocyte apoptotic processGO:0071887710.015
regulation of synaptic plasticityGO:0048167870.015
organonitrogen compound biosynthetic processGO:19015661920.015
regulation of mitotic cell cycleGO:00073461260.015
circulatory system processGO:00030131970.015
cell activation involved in immune responseGO:00022631260.015
glycosyl compound catabolic processGO:19016582060.015
myeloid cell apoptotic processGO:0033028220.015
cellular response to hormone stimulusGO:00328701500.015
positive regulation of cytosolic calcium ion concentrationGO:0007204650.015
purine ribonucleoside catabolic processGO:00461302050.014
regulation of cell cycleGO:00517262810.014
myeloid cell differentiationGO:00300992330.014
regulation of cell substrate adhesionGO:0010810730.014
response to organonitrogen compoundGO:00102432460.014
multicellular organismal homeostasisGO:00488711640.014
regulation of transferase activityGO:00513382630.014
small molecule biosynthetic processGO:00442831320.014
glycerolipid metabolic processGO:00464861220.014
glycosyl compound metabolic processGO:19016572460.014
organelle localizationGO:00516401790.014
fatty acid derivative transportGO:1901571140.014
germ cell developmentGO:00072811850.014
epidermis developmentGO:00085441870.014
purine ribonucleoside triphosphate catabolic processGO:00092071990.014
defense response to bacteriumGO:00427421190.014
tissue homeostasisGO:00018941150.014
regulation of t cell activationGO:00508631700.014
regulation of body fluid levelsGO:00508781620.014
interleukin 8 productionGO:003263740.014
ribonucleoside catabolic processGO:00424542060.014
regulation of protein catabolic processGO:00421761080.014
heart morphogenesisGO:00030071780.014
canonical wnt signaling pathwayGO:00600701300.014
transition metal ion homeostasisGO:0055076540.014
carbohydrate derivative biosynthetic processGO:19011371830.014
protein localization to organelleGO:00333651850.013
sequestering of metal ionGO:0051238190.013
leukocyte activation involved in immune responseGO:00023661260.013
positive regulation of cell developmentGO:00107202370.013
lipid biosynthetic processGO:00086101790.013
icosanoid secretionGO:0032309120.013
chemotaxisGO:00069352470.013
cellular protein complex assemblyGO:00436231160.013
bone remodelingGO:0046849530.013
cellular amide metabolic processGO:0043603580.013
cognitionGO:00508901490.013
positive regulation of protein phosphorylationGO:00019342420.013
protein kinase b signalingGO:0043491740.013
establishment of vesicle localizationGO:0051650810.013
regulation of establishment of protein localizationGO:00702011810.013
positive regulation of secretion by cellGO:19035321140.013
digestive system developmentGO:00551232000.013
regulation of myeloid cell apoptotic processGO:0033032190.013
regulation of neuron differentiationGO:00456642810.013
membrane lipid metabolic processGO:0006643530.013
alpha beta t cell activationGO:0046631910.013
stem cell differentiationGO:00488632680.013
purine containing compound catabolic processGO:00725232130.013
segmentationGO:0035282930.013
regulation of leukocyte apoptotic processGO:2000106560.013
positive regulation of cell migrationGO:00303351090.013
organonitrogen compound catabolic processGO:19015652640.013
action potentialGO:0001508780.012
early endosome to late endosome transportGO:004502220.012
cellular water homeostasisGO:000999220.012
peptide secretionGO:00027901140.012
regulated secretory pathwayGO:0045055320.012
ribonucleoside monophosphate catabolic processGO:0009158570.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.012
purine ribonucleoside triphosphate metabolic processGO:00092052200.012
regulation of satellite cell activation involved in skeletal muscle regenerationGO:001471730.012
regulation of ion transportGO:00432692150.012
pigmentationGO:0043473710.012
leukocyte proliferationGO:00706611720.012
membrane fusionGO:0061025380.012
cell type specific apoptotic processGO:00972852680.012
neuronal action potentialGO:0019228540.012
single organismal cell cell adhesionGO:00163371310.012
peptide transportGO:00158331330.012
camera type eye developmentGO:00430102660.012
cytoplasmic transportGO:00164822340.012
regulation of proteolysisGO:00301621640.012
adult locomotory behaviorGO:0008344910.012
anatomical structure homeostasisGO:00602491450.012
positive regulation of cell cycle processGO:0090068610.012
ribonucleoside triphosphate catabolic processGO:00092031990.012
positive regulation of nervous system developmentGO:00519622210.012
glial cell differentiationGO:00100011310.012
carboxylic acid biosynthetic processGO:0046394860.012
negative regulation of phosphate metabolic processGO:00459361840.012
atp metabolic processGO:0046034750.012
regulation of lymphocyte proliferationGO:00506701170.012
ras protein signal transductionGO:0007265770.012
multicellular organismal signalingGO:0035637910.012
negative regulation of cellular protein metabolic processGO:00322692470.011
forebrain developmentGO:00309003020.011
amino acid transportGO:0006865610.011
sensory perceptionGO:00076002450.011
ear developmentGO:00435832000.011
morphogenesis of a branching epitheliumGO:00611381930.011
purine containing compound metabolic processGO:00725213110.011
cellular response to acid chemicalGO:0071229680.011
regulation of kinase activityGO:00435492490.011
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.011
spermatogenesisGO:00072832840.011
epithelial cell developmentGO:00020641590.011
positive regulation of kinase activityGO:00336741550.011
wound healingGO:00420601570.011
alcohol metabolic processGO:00060661160.011
cardiac chamber developmentGO:00032051080.011
extracellular matrix organizationGO:00301981470.011
regulation of ion transmembrane transportGO:00347651190.011
ribonucleoside metabolic processGO:00091192450.011
mesoderm morphogenesisGO:0048332640.011
glycoprotein biosynthetic processGO:0009101890.011
purine nucleoside triphosphate metabolic processGO:00091442260.011
organic acid biosynthetic processGO:0016053860.011
respiratory system developmentGO:00605411900.011
intrinsic apoptotic signaling pathwayGO:00971931320.011
fatty acid transportGO:0015908280.011
l amino acid transportGO:0015807320.011
myeloid leukocyte differentiationGO:00025731190.011
regulation of multi organism processGO:00439001110.011
leukocyte migrationGO:00509001240.011
extracellular structure organizationGO:00430621480.011
protein maturationGO:00516041760.011
inter male aggressive behaviorGO:000212130.011
regulation of synapse structural plasticityGO:005182340.011
defense response to other organismGO:00985421970.011
maintenance of locationGO:0051235890.011
negative regulation of protein phosphorylationGO:00019331260.011
cytosolic calcium ion homeostasisGO:0051480700.011
sensory system developmentGO:004888030.011
regulation of vascular smooth muscle contractionGO:000305610.011
regulation of neurotransmitter levelsGO:0001505870.011
sequestering of calcium ionGO:0051208180.010
smoothened signaling pathwayGO:00072241050.010
neuromuscular processGO:0050905990.010
establishment of protein localization to membraneGO:0090150540.010
response to inorganic substanceGO:0010035960.010
positive regulation of protein serine threonine kinase activityGO:00719021060.010
cellular response to molecule of bacterial originGO:0071219830.010
positive regulation of organelle organizationGO:00106381280.010
response to lipopolysaccharideGO:00324961280.010
keratinocyte migrationGO:005154630.010
nucleoside monophosphate metabolic processGO:0009123850.010
regulation of actin filament based processGO:0032970990.010
regulation of mitotic cell cycle phase transitionGO:1901990730.010
lateral line system developmentGO:004892510.010
regulation of cytoskeleton organizationGO:00514931220.010
hydrogen ion transmembrane transportGO:1902600250.010
regulation of cell cycle phase transitionGO:1901987770.010
myeloid cell homeostasisGO:00022621140.010
monosaccharide metabolic processGO:00059961060.010
b cell differentiationGO:0030183780.010
regulation of coagulationGO:0050818310.010
regulation of protein stabilityGO:0031647520.010
regulation of systemic arterial blood pressureGO:0003073610.010
regulation of cellular component sizeGO:00325351210.010
purine ribonucleoside monophosphate metabolic processGO:0009167800.010
negative regulation of secretion by cellGO:1903531540.010
exosomal secretionGO:199018210.010

Degs1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.276
disease of metabolismDOID:001466700.276
disease of anatomical entityDOID:700.051
nervous system diseaseDOID:86300.051
brain diseaseDOID:93600.023
central nervous system diseaseDOID:33100.023
lysosomal storage diseaseDOID:321100.022
neuropathyDOID:87000.018
musculoskeletal system diseaseDOID:1700.014
charcot marie tooth diseaseDOID:1059500.014
neuromuscular diseaseDOID:44000.014
epilepsy syndromeDOID:182600.013
electroclinical syndromeDOID:005070100.013
carbohydrate metabolic disorderDOID:297800.012
connective tissue diseaseDOID:6500.011
bone diseaseDOID:008000100.011
bone development diseaseDOID:008000600.011