Mus musculus

44 known processes

Sh2d1a

SH2 domain protein 1A

(Aliases: SAP,Gm686)

Sh2d1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
natural killer cell activationGO:0030101440.966
Mouse
stimulatory c type lectin receptor signaling pathwayGO:000222320.735
immune response activating cell surface receptor signaling pathwayGO:0002429720.725
immune response regulating cell surface receptor signaling pathwayGO:0002768800.689
Mouse
membrane fusionGO:0061025380.663
regulation of cellular ketone metabolic processGO:0010565660.556
positive regulation of interleukin 2 biosynthetic processGO:004508680.551
dna metabolic processGO:00062593030.546
apoptotic signaling pathwayGO:00971903060.539
positive regulation of cellular amino acid metabolic processGO:004576430.535
t cell selectionGO:0045058340.534
vesicle fusionGO:0006906160.519
regulation of vesicle fusionGO:003133860.513
regulation of cell activationGO:00508652890.501
Mouse
regulation of interleukin 2 biosynthetic processGO:0045076130.474
antigen receptor mediated signaling pathwayGO:0050851640.432
natural killer cell inhibitory signaling pathwayGO:000276920.432
Mouse
t cell activationGO:00421102890.420
thymic t cell selectionGO:0045061220.413
organelle fusionGO:0048284280.411
interleukin 2 productionGO:0032623330.354
regulation of cellular amino acid metabolic processGO:000652150.344
granzyme mediated apoptotic signaling pathwayGO:000862610.313
t cell differentiationGO:00302171740.308
regulation of innate immune responseGO:0045088910.308
peptidyl amino acid modificationGO:00181933360.300
Mouse
negative t cell selectionGO:0043383130.292
interleukin 2 biosynthetic processGO:0042094150.278
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.271
dna recombinationGO:0006310920.252
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.247
vesicle organizationGO:0016050600.244
amine metabolic processGO:0009308450.244
regulation of natural killer cell activationGO:0032814220.244
Mouse
leukocyte proliferationGO:00706611720.233
positive regulation of t cell receptor signaling pathwayGO:005086240.227
somatic recombination of immunoglobulin gene segmentsGO:0016447420.216
immune effector processGO:00022523210.216
somatic cell dna recombinationGO:0016444510.215
positive regulation of lymphocyte activationGO:00512511400.215
innate immune response activating cell surface receptor signaling pathwayGO:000222040.213
cellular amino acid metabolic processGO:00065201030.209
positive regulation of cellular amine metabolic processGO:003324050.207
positive regulation of lymphocyte proliferationGO:0050671700.207
alpha beta t cell proliferationGO:0046633210.204
lymphocyte anergyGO:000224940.200
cellular response to molecule of fungal originGO:007122620.199
regulation of cytokine productionGO:00018172660.190
Mouse
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.181
regulation of interferon gamma productionGO:0032649570.179
Mouse
cellular amine metabolic processGO:0044106440.177
somatic diversification of immune receptorsGO:0002200530.175
t cell costimulationGO:0031295140.170
regulation of alpha beta t cell proliferationGO:0046640180.165
natural killer cell mediated immunityGO:0002228290.164
cytokine productionGO:00018163190.163
Mouse
immune response activating signal transductionGO:00027571160.162
regulation of lymphocyte activationGO:00512492400.159
Mouse
negative thymic t cell selectionGO:0045060120.159
cell killingGO:0001906670.159
positive regulation of protein kinase b signalingGO:0051897320.157
positive regulation of cytokine biosynthetic processGO:0042108400.152
lymphocyte costimulationGO:0031294150.146
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.144
adaptive immune responseGO:00022501550.143
interleukin 10 secretionGO:007260840.142
regulation of cellular amine metabolic processGO:0033238200.141
positive regulation of cell killingGO:0031343330.135
interferon gamma productionGO:0032609670.126
Mouse
leukocyte mediated immunityGO:00024431740.125
cellular response to cytokine stimulusGO:00713451890.122
negative regulation of cellular amine metabolic processGO:003323910.119
positive regulation of alpha beta t cell activationGO:0046635390.111
positive regulation of alpha beta t cell proliferationGO:0046641120.110
positive regulation of natural killer cell mediated immunityGO:0002717160.110
positive regulation of t cell proliferationGO:0042102520.108
lymphocyte mediated immunityGO:00024491390.104
cellular response to lipidGO:00713961450.102
detection of fungusGO:001604620.100
positive regulation of isotype switching to igg isotypesGO:004830470.098
negative regulation of apoptotic signaling pathwayGO:20012341040.098
leukocyte differentiationGO:00025213420.091
leukocyte mediated cytotoxicityGO:0001909620.089
regulation of organelle organizationGO:00330432890.087
defense response to other organismGO:00985421970.087
negative regulation of cellular amino acid metabolic processGO:004576300.086
reactive oxygen species metabolic processGO:0072593840.085
positive regulation of production of molecular mediator of immune responseGO:0002702450.084
lymphocyte differentiationGO:00300982420.083
b cell activation involved in immune responseGO:0002312500.082
regulation of alpha beta t cell activationGO:0046634530.081
positive regulation of adaptive immune responseGO:0002821610.080
positive regulation of lymphocyte anergyGO:000291340.080
extrinsic apoptotic signaling pathwayGO:00971911260.079
regulation of interleukin 2 productionGO:0032663280.079
immunoglobulin productionGO:0002377730.078
positive regulation of lymphocyte mediated immunityGO:0002708620.077
leukocyte activation involved in immune responseGO:00023661260.077
Mouse
ameboidal type cell migrationGO:00016671280.073
g protein coupled receptor signaling pathwayGO:00071862430.073
regulation of t cell activationGO:00508631700.073
protein kinase b signalingGO:0043491740.072
single organismal cell cell adhesionGO:00163371310.072
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.071
regulation of t cell anergyGO:000266740.068
cellular ketone metabolic processGO:0042180840.064
alpha beta t cell activationGO:0046631910.062
t cell differentiation in thymusGO:0033077770.061
t cell anergyGO:000287040.061
somatic diversification of immunoglobulinsGO:0016445430.061
regulation of lymphocyte anergyGO:000291140.061
regulation of defense responseGO:00313472330.060
natural killer cell mediated cytotoxicityGO:0042267290.058
cell surface pattern recognition receptor signaling pathwayGO:000275220.058
gamma delta t cell lineage commitmentGO:000236510.058
lymphocyte activation involved in immune responseGO:0002285930.056
response to molecule of fungal originGO:000223840.055
striated muscle tissue developmentGO:00147062930.055
positive regulation of dna recombinationGO:0045911170.055
immune response regulating signaling pathwayGO:00027641250.055
Mouse
cytokine metabolic processGO:0042107710.055
regulation of body fluid levelsGO:00508781620.052
positive regulation of leukocyte proliferationGO:0070665730.052
b cell activationGO:00421131610.052
positive regulation of t cell costimulationGO:200052520.052
isotype switching to igg isotypesGO:0048291100.050
positive t cell selectionGO:0043368230.049
positive regulation of interleukin 2 productionGO:0032743190.049
regulation of lymphocyte mediated immunityGO:0002706840.049
regulation of cytokine biosynthetic processGO:0042035590.048
negative regulation of immune effector processGO:0002698550.047
Mouse
cellular response to biotic stimulusGO:0071216920.047
blood circulationGO:00080151950.046
regulation of homotypic cell cell adhesionGO:0034110130.046
regulation of reactive oxygen species biosynthetic processGO:190342620.045
regulation of ion transportGO:00432692150.044
positive regulation of t cell anergyGO:000266940.044
regulation of protein transportGO:00512231630.044
cellular response to organonitrogen compoundGO:00714171450.043
response to peptideGO:19016521360.043
positive regulation of cytokine productionGO:00018191740.043
regulation of t cell costimulationGO:200052320.043
interleukin 12 secretionGO:007261030.042
positive regulation of t cell activationGO:00508701010.041
regulation of protein maturationGO:1903317960.041
positive regulation of isotype switchingGO:0045830150.041
regulation of vesicle mediated transportGO:00606271390.040
single organism cell adhesionGO:00986021560.040
response to lipopolysaccharideGO:00324961280.039
inflammatory response to antigenic stimulusGO:0002437300.039
regulation of dna recombinationGO:0000018340.038
regulation of angiogenesisGO:0045765810.038
b cell mediated immunityGO:0019724710.038
regulation of angiotensin metabolic processGO:006017740.037
t cell receptor signaling pathwayGO:0050852460.037
cell activation involved in immune responseGO:00022631260.037
Mouse
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.036
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.036
Mouse
b cell receptor signaling pathwayGO:0050853200.035
membrane organizationGO:00610242450.035
multicellular organismal signalingGO:0035637910.035
neuron deathGO:00709971540.034
positive regulation of leukocyte mediated immunityGO:0002705700.034
alpha beta t cell differentiationGO:0046632690.034
transmission of nerve impulseGO:0019226760.034
regulation of antigen receptor mediated signaling pathwayGO:0050854290.033
regulation of cell cycleGO:00517262810.033
negative regulation of cellular component organizationGO:00511291940.033
carbohydrate metabolic processGO:00059752300.032
sensory organ morphogenesisGO:00905962420.032
production of molecular mediator of immune responseGO:00024401030.032
negative regulation of hydrolase activityGO:0051346710.032
positive regulation of cell deathGO:00109422240.032
inositol lipid mediated signalingGO:0048017410.031
peptidyl tyrosine modificationGO:00182121450.030
Mouse
regulation of establishment of protein localizationGO:00702011810.030
cellular lipid metabolic processGO:00442553230.030
regulation of cysteine type endopeptidase activityGO:2000116650.030
positive thymic t cell selectionGO:0045059130.029
microglia developmentGO:001400520.029
positive regulation of reactive oxygen species biosynthetic processGO:190342820.029
negative regulation of protein metabolic processGO:00512482820.029
Mouse
positive regulation of inflammatory response to antigenic stimulusGO:0002863110.029
cell adhesionGO:00071553290.029
detection of yeastGO:000187920.029
microglial cell activationGO:000177430.029
cell type specific apoptotic processGO:00972852680.028
regulation of leukocyte mediated cytotoxicityGO:0001910380.028
negative regulation of growthGO:0045926990.028
phosphatidylinositol mediated signalingGO:0048015410.028
interleukin 8 secretionGO:007260630.028
cation transportGO:00068123990.028
neutrophil mediated killing of gram positive bacteriumGO:007094620.027
t cell proliferationGO:00420981200.027
nuclear transportGO:00511691390.027
protein maturationGO:00516041760.027
oxidation reduction processGO:00551143420.027
carbohydrate homeostasisGO:00335001280.027
regulation of immunoglobulin mediated immune responseGO:0002889370.026
reactive oxygen species biosynthetic processGO:190340980.026
cellular response to hormone stimulusGO:00328701500.026
regulation of angiotensin levels in bloodGO:000200240.026
cellular response to dna damage stimulusGO:00069742070.026
muscle tissue developmentGO:00605373080.025
isotype switchingGO:0045190360.025
regulation of apoptotic signaling pathwayGO:20012331970.025
interleukin 4 productionGO:0032633240.025
regulation of proteolysisGO:00301621640.025
regulation of cell migrationGO:00303342190.025
positive regulation of organelle organizationGO:00106381280.024
regulation of cell cycle processGO:00105641600.024
regulation of interleukin 8 secretionGO:200048220.024
regulation of peptidase activityGO:0052547960.024
microtubule based processGO:00070172360.024
regulation of leukocyte mediated immunityGO:00027031040.024
neutrophil mediated killing of symbiont cellGO:007094380.024
cellular response to peptide hormone stimulusGO:0071375920.023
mapk cascadeGO:00001652810.023
regulation of isotype switchingGO:0045191220.023
negative regulation of lymphocyte apoptotic processGO:0070229240.023
cd8 positive alpha beta t cell extravasationGO:003569730.022
regulation of phosphatidylinositol 3 kinase signalingGO:0014066300.022
cellular homeostasisGO:00197252400.022
eosinophil activationGO:004330710.022
regulation of isotype switching to igg isotypesGO:0048302100.022
intrinsic apoptotic signaling pathwayGO:00971931320.021
regulation of peptidyl tyrosine phosphorylationGO:0050730930.021
Mouse
positive regulation of cell projection organizationGO:0031346950.021
locomotory behaviorGO:00076261950.021
neuron apoptotic processGO:00514021420.021
regulation of protein kinase b signalingGO:0051896560.021
regulation of secretion by cellGO:19035302490.021
negative regulation of t cell apoptotic processGO:0070233180.021
regulation of eosinophil degranulationGO:004330910.021
alpha beta t cell lineage commitmentGO:000236370.021
positive regulation of reactive oxygen species metabolic processGO:2000379110.020
t cell differentiation involved in immune responseGO:0002292300.020
nuclear divisionGO:00002801580.020
circulatory system processGO:00030131970.020
regulation of mapk cascadeGO:00434082480.020
regulation of endocytosisGO:0030100690.020
negative regulation of phosphorylationGO:00423261660.020
Mouse
pyridine containing compound catabolic processGO:007252640.020
positive regulation of apoptotic signaling pathwayGO:2001235950.020
cellular protein complex assemblyGO:00436231160.020
regulation of b cell activationGO:0050864810.020
phosphatidylinositol 3 kinase signalingGO:0014065360.020
t helper cell differentiationGO:0042093280.020
t cell activation involved in immune responseGO:0002286430.019
monosaccharide metabolic processGO:00059961060.019
negative regulation of peptidase activityGO:0010466460.019
regulation of cd8 positive alpha beta t cell extravasationGO:200044930.019
organelle fissionGO:00482851700.019
divalent inorganic cation homeostasisGO:00725071380.019
cell recognitionGO:0008037830.019
hexose metabolic processGO:0019318980.019
regulation of mitotic cell cycleGO:00073461260.019
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.018
response to insulinGO:00328681000.018
interleukin 2 mediated signaling pathwayGO:003811020.018
striated muscle cell developmentGO:00550021250.018
maintenance of locationGO:0051235890.018
positive regulation of immune effector processGO:00026991070.018
inner cell mass cell proliferationGO:0001833150.018
protein homooligomerizationGO:0051260430.018
regulation of response to woundingGO:19030341890.018
regulation of interferon gamma secretionGO:190271330.018
regulation of homeostatic processGO:00328441820.018
negative regulation of protein maturationGO:1903318790.018
ear morphogenesisGO:00424711180.018
glycosyl compound metabolic processGO:19016572460.018
negative regulation of natural killer cell mediated immunityGO:000271650.018
Mouse
sulfur compound metabolic processGO:00067901000.018
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.018
blastocyst growthGO:0001832230.017
germ cell developmentGO:00072811850.017
rho protein signal transductionGO:0007266320.017
nonribosomal peptide biosynthetic processGO:001918450.017
regulation of t helper 2 cell cytokine productionGO:200055130.017
negative regulation of protein processingGO:0010955790.017
cd4 positive alpha beta t cell differentiationGO:0043367410.017
insulin receptor signaling pathwayGO:0008286490.017
symbiosis encompassing mutualism through parasitismGO:0044403830.017
positive regulation of defense responseGO:00313491240.017
retina development in camera type eyeGO:00600411190.017
stem cell differentiationGO:00488632680.017
protein localization to membraneGO:00726571080.017
positive regulation of innate immune responseGO:0045089800.017
regulation of b cell proliferationGO:0030888390.017
regulation of inflammatory response to antigenic stimulusGO:0002861210.016
regulation of cell divisionGO:0051302760.016
t helper 17 cell lineage commitmentGO:007254040.016
negative regulation of multi organism processGO:0043901680.016
detection of other organismGO:009854380.016
negative regulation of protein modification processGO:00314001630.016
Mouse
regulation of interleukin 8 productionGO:003267730.016
cellular response to insulin stimulusGO:0032869780.016
negative regulation of molecular functionGO:00440922580.016
regulation of blood pressureGO:0008217930.016
cellular metal ion homeostasisGO:00068751510.016
positive regulation of inflammatory responseGO:0050729470.016
positive regulation of t helper 1 cell differentiationGO:004562740.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.016
inflammatory responseGO:00069542440.016
positive regulation of immunoglobulin productionGO:0002639280.016
smoothened signaling pathwayGO:00072241050.016
ear developmentGO:00435832000.016
cellular response to transforming growth factor beta stimulusGO:0071560880.016
angiogenesisGO:00015252010.015
pyridine nucleotide catabolic processGO:001936430.015
alpha beta t cell activation involved in immune responseGO:0002287310.015
t helper 2 cell cytokine productionGO:003574540.015
skeletal muscle organ developmentGO:00605381630.015
embryonic placenta developmentGO:0001892980.015
regulation of neuron deathGO:19012141340.015
positive regulation of cell activationGO:00508671580.015
helper t cell chemotaxisGO:003570410.015
citrate metabolic processGO:000610130.015
positive regulation of b cell activationGO:0050871490.015
regulation of interleukin 4 biosynthetic processGO:004540230.015
regulation of neuron differentiationGO:00456642810.015
mitotic cell cycleGO:00002781950.015
mitotic cell cycle processGO:19030471590.015
cellular carbohydrate metabolic processGO:00442621190.015
response to peptide hormoneGO:00434341270.014
progesterone metabolic processGO:004244840.014
regulation of production of molecular mediator of immune responseGO:0002700650.014
protein modification by small protein conjugationGO:00324461870.014
positive regulation of interleukin 13 productionGO:003273640.014
positive regulation of interleukin 8 secretionGO:200048410.014
action potentialGO:0001508780.014
second messenger mediated signalingGO:0019932730.014
regulation of myeloid cell differentiationGO:0045637960.014
mitochondrion organizationGO:00070051340.014
regulation of endopeptidase activityGO:0052548890.014
sensory perceptionGO:00076002450.014
regulation of t cell extravasationGO:200040730.014
regulation of phospholipase c activityGO:190027430.014
regulation of immunoglobulin productionGO:0002637420.014
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001239260.014
blastocyst developmentGO:0001824800.014
regulation of nucleocytoplasmic transportGO:0046822730.014
negative regulation of regulatory t cell differentiationGO:004559020.014
cd4 positive or cd8 positive alpha beta t cell lineage commitmentGO:004336980.014
positive regulation of cd8 positive alpha beta t cell extravasationGO:200045120.014
cell fate commitmentGO:00451652100.014
nucleotide metabolic processGO:00091173320.014
nucleobase containing small molecule metabolic processGO:00550863520.014
immune complex clearanceGO:000243420.014
regulation of adaptive immune responseGO:0002819900.014
positive regulation of cell adhesionGO:0045785800.013
positive regulation of phosphatidylinositol 3 kinase signalingGO:0014068200.013
cellular calcium ion homeostasisGO:00068741190.013
morphogenesis of a branching structureGO:00017632030.013
regulation of t cell proliferationGO:0042129920.013
t cell lineage commitmentGO:0002360130.013
regulation of t cell tolerance inductionGO:000266460.013
regulation of systemic arterial blood pressure mediated by a chemical signalGO:0003044330.013
positive regulation of b cell mediated immunityGO:0002714260.013
posttranscriptional regulation of gene expressionGO:00106081550.013
platelet morphogenesisGO:0036344130.013
regulation of kinase activityGO:00435492490.013
granulocyte activationGO:0036230100.013
meiotic cell cycleGO:00513211220.013
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.013
chromatin organizationGO:00063252060.013
regulation of protein kinase activityGO:00458592320.013
dephosphorylationGO:00163111290.013
glucose metabolic processGO:0006006920.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.013
regulation of peptide hormone secretionGO:0090276750.013
transmembrane transportGO:00550854120.013
regulation of calcium ion transport into cytosolGO:0010522310.013
immunoglobulin mediated immune responseGO:0016064690.013
skeletal muscle myosin thick filament assemblyGO:003024110.013
fatty acid metabolic processGO:00066311210.013
inner ear morphogenesisGO:00424721010.012
hormone metabolic processGO:0042445860.012
t helper 2 cell differentiationGO:0045064120.012
cellular response to peptideGO:1901653920.012
positive regulation of alpha beta t cell differentiationGO:0046638280.012
detection of biotic stimulusGO:0009595100.012
regulation of immunological synapse formationGO:200052020.012
regulation of peptide transportGO:0090087910.012
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.012
positive regulation of phospholipase c activityGO:001086320.012
peptide transportGO:00158331330.012
regulation of vasculature developmentGO:1901342880.012
regulation of cell killingGO:0031341400.012
regulation of natural killer cell mediated immunityGO:0002715190.012
negative regulation of intracellular signal transductionGO:19025321670.012
intracellular protein transportGO:00068862040.012
negative regulation of eosinophil degranulationGO:004331010.012
gamma delta t cell differentiationGO:0042492110.012
negative regulation of leukocyte mediated immunityGO:0002704290.012
Mouse
negative regulation of t cell activationGO:0050868650.012
regulation of protein processingGO:0070613960.012
innate immune response activating signal transductionGO:0002758500.012
generation of precursor metabolites and energyGO:00060911030.012
regulation of b cell differentiationGO:0045577230.012
immune response inhibiting signal transductionGO:000276540.012
Mouse
regulation of membrane potentialGO:00423911920.012
regulation of multi organism processGO:00439001110.012
synaptic transmissionGO:00072683290.012
glycosyl compound catabolic processGO:19016582060.012
actin cytoskeleton reorganizationGO:0031532210.012
myeloid leukocyte differentiationGO:00025731190.012
regulation of cell adhesionGO:00301551540.012
organic acid biosynthetic processGO:0016053860.012
cellular component assembly involved in morphogenesisGO:00109271390.012
peptide secretionGO:00027901140.012
actin filament polymerizationGO:0030041440.011
kit signaling pathwayGO:003810930.011
endomembrane system organizationGO:00102561470.011
tissue remodelingGO:00487711020.011
necroptotic signaling pathwayGO:009752730.011
regulation of smoothened signaling pathwayGO:0008589580.011
regulation of cytoplasmic transportGO:19036491120.011
eosinophil mediated immunityGO:000244710.011
monocarboxylic acid metabolic processGO:00327871910.011
myosin filament assemblyGO:003103420.011
antigen processing and presentationGO:0019882470.011
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001240160.011
regulation of reactive oxygen species metabolic processGO:2000377400.011
regulation of system processGO:00440572000.011
microglia differentiationGO:001400420.011
peptidyl tyrosine phosphorylationGO:00181081430.011
Mouse
extracellular structure organizationGO:00430621480.011
regulation of hormone levelsGO:00108172110.011
negative regulation of smoothened signaling pathwayGO:0045879250.011
response to growth factorGO:00708481980.011
skin developmentGO:00435882200.011
cellular response to testosterone stimulusGO:007139410.011
interspecies interaction between organismsGO:0044419830.011
nitric oxide metabolic processGO:0046209250.011
glucose homeostasisGO:00425931280.011
camera type eye developmentGO:00430102660.011
activation of immune responseGO:00022531380.011
cellular response to oxidative stressGO:0034599760.011
positive regulation of antigen receptor mediated signaling pathwayGO:005085790.011
cdc42 protein signal transductionGO:003248800.011
cell cell recognitionGO:0009988440.011
microtubule based movementGO:0007018840.011
negative regulation of leukocyte apoptotic processGO:2000107310.011
branching morphogenesis of an epithelial tubeGO:00487541590.011
neuronal action potentialGO:0019228540.011
extracellular matrix organizationGO:00301981470.011
regulation of vacuole organizationGO:004408840.010
heart contractionGO:0060047930.010
mesodermal cell migrationGO:000807840.010
b cell proliferationGO:0042100530.010
negative regulation of synapse assemblyGO:005196430.010
regulation of cell projection organizationGO:00313442060.010
positive regulation of b cell receptor signaling pathwayGO:005086140.010
positive regulation of phospholipase activityGO:001051830.010
forebrain developmentGO:00309003020.010
positive regulation of programmed cell deathGO:00430682180.010
energy derivation by oxidation of organic compoundsGO:0015980770.010
organic acid transportGO:00158491010.010
striated muscle myosin thick filament assemblyGO:007168810.010
nucleic acid phosphodiester bond hydrolysisGO:0090305490.010
response to testosteroneGO:003357430.010
regulation of synaptic growth at neuromuscular junctionGO:000858240.010
actin cytoskeleton organizationGO:00300362200.010
signal transduction in absence of ligandGO:0038034550.010

Sh2d1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
connective tissue diseaseDOID:6500.020
disease of anatomical entityDOID:700.020
musculoskeletal system diseaseDOID:1700.020
immune system diseaseDOID:291400.014
disease of metabolismDOID:001466700.012
sensory system diseaseDOID:005015500.011
nervous system diseaseDOID:86300.011
eye and adnexa diseaseDOID:149200.011
organ system cancerDOID:005068600.011
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011
retinitis pigmentosaDOID:1058400.010
eye diseaseDOID:561400.010
retinal diseaseDOID:567900.010
retinal degenerationDOID:846600.010
hypersensitivity reaction type ii diseaseDOID:41700.010
hypersensitivity reaction diseaseDOID:006005600.010