Mus musculus

7 known processes

Bace1

beta-site APP cleaving enzyme 1

(Aliases: C76936)

Bace1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of synaptic growth at neuromuscular junctionGO:000858240.088
regulation of neuron differentiationGO:00456642810.084
synaptic transmissionGO:00072683290.063
cognitionGO:00508901490.062
regulation of cellular amine metabolic processGO:0033238200.059
regulation of cellular amino acid metabolic processGO:000652150.053
microtubule based processGO:00070172360.053
positive regulation of nervous system developmentGO:00519622210.050
cellular amine metabolic processGO:0044106440.049
negative regulation of cellular component organizationGO:00511291940.047
axon guidanceGO:00074111410.046
amine metabolic processGO:0009308450.046
vesicle localizationGO:0051648860.045
purine containing compound metabolic processGO:00725213110.045
endomembrane system organizationGO:00102561470.045
cellular amino acid metabolic processGO:00065201030.045
synaptic vesicle localizationGO:0097479590.043
regulation of cellular ketone metabolic processGO:0010565660.043
forebrain developmentGO:00309003020.043
action potentialGO:0001508780.043
nucleobase containing small molecule metabolic processGO:00550863520.042
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.042
peptidyl amino acid modificationGO:00181933360.041
cellular homeostasisGO:00197252400.041
axonogenesisGO:00074092740.040
golgi to endosome transportGO:000689530.039
positive regulation of cellular amine metabolic processGO:003324050.039
purine nucleotide metabolic processGO:00061633020.038
membrane organizationGO:00610242450.038
learning or memoryGO:00076111480.038
ribose phosphate metabolic processGO:00196932910.038
ribonucleotide metabolic processGO:00092592910.037
synapse organizationGO:00508081250.037
regulation of transferase activityGO:00513382630.037
glycoprotein metabolic processGO:00091001160.037
regulation of membrane potentialGO:00423911920.037
establishment of organelle localizationGO:00516561220.037
establishment of vesicle localizationGO:0051650810.036
negative regulation of nervous system developmentGO:00519611560.036
carbohydrate derivative catabolic processGO:19011362310.036
gastrulationGO:00073691160.035
regulation of protein kinase activityGO:00458592320.035
nucleoside phosphate metabolic processGO:00067533380.034
neuronal action potentialGO:0019228540.034
regulation of neuron projection developmentGO:00109751690.033
regulation of anatomical structure sizeGO:00900661780.033
regulation of secretionGO:00510462740.033
regulation of cellular component biogenesisGO:00440871810.033
cellular ketone metabolic processGO:0042180840.033
positive regulation of cellular amino acid metabolic processGO:004576430.032
cellular protein complex assemblyGO:00436231160.032
purine ribonucleotide metabolic processGO:00091502900.032
nitrogen compound transportGO:00717052710.032
protein modification by small protein conjugationGO:00324461870.032
regulation of cellular component sizeGO:00325351210.031
response to light stimulusGO:00094161350.031
regulation of organelle organizationGO:00330432890.031
neuron projection guidanceGO:00974851410.031
negative regulation of protein metabolic processGO:00512482820.030
muscle system processGO:00030121410.030
carbohydrate derivative biosynthetic processGO:19011371830.030
regulation of cell projection organizationGO:00313442060.029
exocytosisGO:00068871210.029
carbohydrate metabolic processGO:00059752300.029
endocytosisGO:00068971680.029
cation transportGO:00068123990.029
negative regulation of molecular functionGO:00440922580.028
camera type eye developmentGO:00430102660.028
sensory perceptionGO:00076002450.028
negative regulation of synapse assemblyGO:005196430.028
chemotaxisGO:00069352470.028
lung developmentGO:00303241640.028
cellular component assembly involved in morphogenesisGO:00109271390.028
regulation of kinase activityGO:00435492490.028
organelle assemblyGO:00709251770.028
transmembrane transportGO:00550854120.028
nucleotide metabolic processGO:00091173320.028
protein localization to membraneGO:00726571080.027
epithelial tube morphogenesisGO:00605623030.027
negative regulation of cell developmentGO:00107211690.027
establishment of synaptic vesicle localizationGO:0097480570.027
regulation of cytoskeleton organizationGO:00514931220.027
synaptic vesicle transportGO:0048489570.027
locomotory behaviorGO:00076261950.026
positive regulation of cell deathGO:00109422240.026
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.026
g protein coupled receptor signaling pathwayGO:00071862430.026
cell adhesionGO:00071553290.026
apoptotic signaling pathwayGO:00971903060.025
hormone secretionGO:00468791280.025
multicellular organismal signalingGO:0035637910.025
organelle localizationGO:00516401790.025
skeletal system developmentGO:00015013560.024
positive regulation of programmed cell deathGO:00430682180.024
ribonucleoside metabolic processGO:00091192450.024
synapse assemblyGO:0007416560.024
regulation of secretion by cellGO:19035302490.023
response to organonitrogen compoundGO:00102432460.023
intracellular protein transportGO:00068862040.023
response to radiationGO:00093141650.023
regulation of system processGO:00440572000.023
actin cytoskeleton organizationGO:00300362200.022
regulation of feeding behaviorGO:006025930.022
organonitrogen compound biosynthetic processGO:19015661920.022
positive regulation of cell developmentGO:00107202370.022
synaptic vesicle recyclingGO:0036465190.022
transmission of nerve impulseGO:0019226760.022
wnt signaling pathwayGO:00160551880.022
nucleoside triphosphate metabolic processGO:00091412300.022
regulation of hormone levelsGO:00108172110.022
oxidation reduction processGO:00551143420.022
positive regulation of protein modification processGO:00314012990.022
protein modification by small protein conjugation or removalGO:00706472070.022
spermatogenesisGO:00072832840.022
protein ubiquitinationGO:00165671710.022
ribonucleoside triphosphate metabolic processGO:00091992200.022
positive regulation of kinase activityGO:00336741550.021
multicellular organism growthGO:00352641610.021
oocyte axis specificationGO:000730920.021
nucleoside phosphate catabolic processGO:19012922220.021
regulation of protein complex assemblyGO:0043254830.021
single organism cell adhesionGO:00986021560.021
cell type specific apoptotic processGO:00972852680.021
glycoprotein biosynthetic processGO:0009101890.021
microtubule based transportGO:0010970500.021
organic hydroxy compound metabolic processGO:19016152030.021
positive regulation of organelle organizationGO:00106381280.021
cation homeostasisGO:00550802120.021
morphogenesis of a branching structureGO:00017632030.021
plasma membrane organizationGO:0007009900.021
protein maturationGO:00516041760.020
myeloid cell differentiationGO:00300992330.020
glycosyl compound metabolic processGO:19016572460.020
long term memoryGO:0007616150.020
heterocycle catabolic processGO:00467002800.020
developmental growth involved in morphogenesisGO:00605601380.020
regulation of cell motilityGO:20001452360.020
developmental maturationGO:00217001930.020
blood circulationGO:00080151950.020
establishment or maintenance of cytoskeleton polarityGO:003095220.020
ensheathment of neuronsGO:0007272760.020
positive regulation of protein kinase activityGO:00458601440.020
ubiquitin dependent protein catabolic processGO:00065111290.020
purine ribonucleoside triphosphate catabolic processGO:00092071990.020
purine ribonucleoside triphosphate metabolic processGO:00092052200.020
cellular chemical homeostasisGO:00550822150.019
regulation of hydrolase activityGO:00513362460.019
macromolecule catabolic processGO:00090572810.019
regulation of vesicle mediated transportGO:00606271390.019
cellular metal ion homeostasisGO:00068751510.019
morphogenesis of a branching epitheliumGO:00611381930.019
regulation of mapk cascadeGO:00434082480.019
negative regulation of cellular protein metabolic processGO:00322692470.019
respiratory system developmentGO:00605411900.019
male courtship behaviorGO:000804920.019
nucleoside metabolic processGO:00091162460.019
regulation of cell morphogenesis involved in differentiationGO:00107691510.019
male gamete generationGO:00482322850.018
purine nucleoside catabolic processGO:00061522050.018
muscle cell differentiationGO:00426922610.018
positive regulation of cellular component biogenesisGO:0044089940.018
ion transmembrane transportGO:00342203610.018
response to organic cyclic compoundGO:00140701980.018
cell recognitionGO:0008037830.018
cation transmembrane transportGO:00986552660.018
cellular response to organonitrogen compoundGO:00714171450.018
central nervous system neuron differentiationGO:00219531620.018
purine nucleotide catabolic processGO:00061952110.018
divalent inorganic cation transportGO:00725111780.018
positive regulation of transferase activityGO:00513471670.018
organonitrogen compound catabolic processGO:19015652640.017
developmental cell growthGO:0048588840.017
associative learningGO:0008306610.017
formation of primary germ layerGO:0001704770.017
digestive system developmentGO:00551232000.017
purine nucleoside metabolic processGO:00422782410.017
regulation of cell cycleGO:00517262810.017
proteolysis involved in cellular protein catabolic processGO:00516031470.017
striated muscle contractionGO:0006941450.017
regulation of lymphocyte activationGO:00512492400.017
oocyte constructionGO:000730820.017
cell growthGO:00160491300.017
negative regulation of cell proliferationGO:00082852960.017
circulatory system processGO:00030131970.017
pole plasm assemblyGO:000731520.017
cellular ion homeostasisGO:00068731650.017
ras protein signal transductionGO:0007265770.017
dephosphorylationGO:00163111290.017
negative regulation of intracellular signal transductionGO:19025321670.017
gland developmentGO:00487323300.017
cellular protein catabolic processGO:00442571550.017
negative regulation of growthGO:0045926990.016
actin polymerization or depolymerizationGO:0008154540.016
posttranscriptional regulation of gene expressionGO:00106081550.016
regulation of establishment of protein localizationGO:00702011810.016
purine containing compound catabolic processGO:00725232130.016
maternal determination of anterior posterior axis embryoGO:000835820.016
germ cell developmentGO:00072811850.016
purine ribonucleoside metabolic processGO:00461282410.016
neuron projection extensionGO:1990138640.016
regulation of cell cycle processGO:00105641600.016
positive regulation of protein phosphorylationGO:00019342420.016
urogenital system developmentGO:00016552610.016
sulfur compound metabolic processGO:00067901000.016
protein processingGO:00164851630.016
hypothalamus gonadotrophin releasing hormone neuron developmentGO:002188840.016
cytoskeleton dependent intracellular transportGO:0030705500.016
skin developmentGO:00435882200.016
muscle tissue developmentGO:00605373080.016
myelinationGO:0042552740.016
organophosphate catabolic processGO:00464342320.016
aromatic compound catabolic processGO:00194392860.016
stem cell differentiationGO:00488632680.016
mitotic cell cycle processGO:19030471590.016
regulation of protein serine threonine kinase activityGO:00719001570.016
neurotransmitter secretionGO:0007269620.015
cytoplasmic transportGO:00164822340.015
extracellular structure organizationGO:00430621480.015
muscle contractionGO:00069361010.015
retrograde transport endosome to golgiGO:004214720.015
negative regulation of cellular amine metabolic processGO:003323910.015
smoothened signaling pathwayGO:00072241050.015
peptide transportGO:00158331330.015
neuromuscular processGO:0050905990.015
engulfment of apoptotic cellGO:004365230.015
rhythmic processGO:00485111740.015
mitochondrion transport along microtubuleGO:004749730.015
glial cell differentiationGO:00100011310.015
respiratory tube developmentGO:00303231670.015
regulation of cellular response to stressGO:00801351590.015
nucleotide catabolic processGO:00091662170.015
vesicle organizationGO:0016050600.015
multi multicellular organism processGO:00447061090.015
lipoprotein metabolic processGO:0042157430.015
oocyte anterior posterior axis specificationGO:000731420.015
negative regulation of cell cycleGO:00457861230.015
positive regulation of neuron differentiationGO:00456661410.015
nucleoside catabolic processGO:00091642060.015
negative regulation of phosphorylationGO:00423261660.015
purine nucleoside triphosphate metabolic processGO:00091442260.015
response to growth factorGO:00708481980.015
amide transportGO:00428861380.015
digestive tract morphogenesisGO:00485461470.015
lateral inhibitionGO:004633110.015
protein localization to plasma membraneGO:0072659570.015
connective tissue developmentGO:00614481790.015
negative regulation of protein phosphorylationGO:00019331260.015
regulation of actin filament lengthGO:0030832450.015
extracellular matrix organizationGO:00301981470.015
multi organism behaviorGO:0051705620.015
mitotic cell cycleGO:00002781950.014
ribonucleotide catabolic processGO:00092612080.014
regulation of actin filament based processGO:0032970990.014
regulation of apoptotic signaling pathwayGO:20012331970.014
positive regulation of cell projection organizationGO:0031346950.014
epithelial cell developmentGO:00020641590.014
regulation of hormone secretionGO:0046883880.014
lipid localizationGO:00108761260.014
organophosphate biosynthetic processGO:00904071220.014
microtubule cytoskeleton organizationGO:00002261570.014
central nervous system neuron developmentGO:0021954670.014
sequestering of calcium ionGO:0051208180.014
carbohydrate homeostasisGO:00335001280.014
mitochondrion organizationGO:00070051340.014
protein polymerizationGO:0051258570.014
immune effector processGO:00022523210.014
meiotic cell cycleGO:00513211220.014
establishment of protein localization to membraneGO:0090150540.014
organic cyclic compound catabolic processGO:19013612950.014
purine ribonucleotide catabolic processGO:00091542080.014
memoryGO:0007613580.014
rho protein signal transductionGO:0007266320.014
cellular nitrogen compound catabolic processGO:00442702800.014
protein glycosylationGO:0006486550.014
learningGO:0007612980.014
small gtpase mediated signal transductionGO:0007264970.014
chromatin organizationGO:00063252060.014
cellular lipid metabolic processGO:00442553230.014
inorganic ion transmembrane transportGO:00986602340.014
purine ribonucleoside catabolic processGO:00461302050.014
negative regulation of protein modification processGO:00314001630.014
blood vessel morphogenesisGO:00485142850.014
microtubule based movementGO:0007018840.014
metencephalon developmentGO:0022037890.013
lipid transportGO:0006869980.013
regulation of protein localizationGO:00328802310.013
cellular divalent inorganic cation homeostasisGO:00725031270.013
purine nucleoside triphosphate catabolic processGO:00091462030.013
neural tube developmentGO:00219151600.013
dendrite developmentGO:00163581150.013
anion transportGO:00068201770.013
nucleoside monophosphate metabolic processGO:0009123850.013
axon ensheathmentGO:0008366760.013
cell cell adhesionGO:0098609410.013
defecationGO:003042110.013
peptide secretionGO:00027901140.013
regulation of cell activationGO:00508652890.013
response to oxidative stressGO:00069791230.013
response to peptideGO:19016521360.013
regulation of intracellular transportGO:00323861590.013
sensory system developmentGO:004888030.013
compound eye developmentGO:004874910.013
dna metabolic processGO:00062593030.013
negative regulation of phosphorus metabolic processGO:00105631840.013
negative regulation of neuron differentiationGO:00456651010.013
positive regulation of apoptotic processGO:00430652170.013
striated muscle tissue developmentGO:00147062930.013
regulation of homeostatic processGO:00328441820.013
regulation of actin cytoskeleton organizationGO:0032956840.013
cellular response to hormone stimulusGO:00328701500.013
sequestering of metal ionGO:0051238190.013
regulation of muscle system processGO:0090257800.013
cerebellum developmentGO:0021549770.013
intracellular mrna localizationGO:000829840.013
protein targetingGO:00066051430.013
establishment or maintenance of cell polarityGO:0007163860.013
rhodopsin mediated signaling pathwayGO:001605640.013
acetylcholine transportGO:001587020.013
regulation of ion transportGO:00432692150.013
regulation of peptidyl tyrosine phosphorylationGO:0050730930.013
glucose homeostasisGO:00425931280.013
cytokine productionGO:00018163190.012
sensory organ morphogenesisGO:00905962420.012
multicellular organismal homeostasisGO:00488711640.012
mesonephric tubule developmentGO:0072164940.012
glycosylationGO:0070085620.012
negative regulation of phosphate metabolic processGO:00459361840.012
regulation of endocytosisGO:0030100690.012
ear developmentGO:00435832000.012
metal ion homeostasisGO:00550651890.012
neuron migrationGO:00017641220.012
morphogenesis of embryonic epitheliumGO:00163311590.012
calcium ion homeostasisGO:00550741270.012
modification dependent protein catabolic processGO:00199411330.012
heart processGO:0003015940.012
lateral line system developmentGO:004892510.012
female sex differentiationGO:0046660840.012
positive regulation of growthGO:00459271040.012
carboxylic acid biosynthetic processGO:0046394860.012
nucleoside triphosphate catabolic processGO:00091432050.012
regulation of cellular catabolic processGO:00313292420.012
protein autophosphorylationGO:0046777610.012
regulation of translationGO:0006417710.012
organelle fissionGO:00482851700.012
cellular response to growth factor stimulusGO:00713631970.012
nucleotide biosynthetic processGO:0009165780.012
peptide hormone secretionGO:00300721090.012
telencephalon developmentGO:00215371860.012
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.012
lipid biosynthetic processGO:00086101790.012
ribonucleoside triphosphate catabolic processGO:00092031990.012
regulation of peptide secretionGO:0002791770.012
stem cell developmentGO:00488642190.012
regulation of nucleotide metabolic processGO:00061401690.012
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.012
cell maturationGO:00484691270.012
neuron deathGO:00709971540.012
regulation of proteolysisGO:00301621640.012
molting cycleGO:0042303900.011
regulation of purine nucleotide metabolic processGO:19005421690.011
establishment of mitochondrion localizationGO:005165440.011
branching morphogenesis of an epithelial tubeGO:00487541590.011
positive regulation of secretion by cellGO:19035321140.011
atp metabolic processGO:0046034750.011
female gamete generationGO:0007292740.011
ribonucleoside monophosphate metabolic processGO:0009161800.011
nuclear divisionGO:00002801580.011
regulation of axon extensionGO:0030516430.011
regulation of actin polymerization or depolymerizationGO:0008064450.011
cellular calcium ion homeostasisGO:00068741190.011
regulation of neurotransmitter levelsGO:0001505870.011
axon cargo transportGO:0008088330.011
regulation of cell growthGO:0001558910.011
embryonic organ morphogenesisGO:00485622760.011
positive regulation of neuron projection developmentGO:0010976790.011
regulation of receptor activityGO:0010469410.011
cellular response to biotic stimulusGO:0071216920.011
divalent metal ion transportGO:00708381720.011
epithelial cell proliferationGO:00506731740.011
myeloid leukocyte differentiationGO:00025731190.011
protein catabolic processGO:00301632210.011
lipid homeostasisGO:0055088630.011
negative regulation of neuron deathGO:1901215980.011
single organismal cell cell adhesionGO:00163371310.011
organic anion transportGO:00157111370.011
kidney developmentGO:00018222130.011
actin filament organizationGO:00070151130.011
adult behaviorGO:00305341350.011
leukocyte migrationGO:00509001240.011
renal system developmentGO:00720012250.011
regulation of endopeptidase activityGO:0052548890.011
cellular response to lipidGO:00713961450.011
anatomical structure homeostasisGO:00602491450.011
cellular carbohydrate metabolic processGO:00442621190.011
retrograde vesicle mediated transport golgi to erGO:000689010.011
neurotransmitter transportGO:0006836760.011
gliogenesisGO:00420631410.011
positive regulation of secretionGO:00510471300.011
regulation of protein processingGO:0070613960.011
ribonucleoside catabolic processGO:00424542060.011
multi organism reproductive behaviorGO:0044705290.011
mapk cascadeGO:00001652810.011
fertilizationGO:00095661270.011
regulation of multi organism processGO:00439001110.011
maintenance of locationGO:0051235890.011
reproductive behaviorGO:0019098320.011
heart morphogenesisGO:00030071780.011
maintenance of presynaptic active zone structureGO:004879010.011
neuron neuron synaptic transmissionGO:0007270690.011
cerebellum morphogenesisGO:0021587420.011
divalent inorganic cation homeostasisGO:00725071380.011
organic hydroxy compound transportGO:0015850930.011
regulation of cell migrationGO:00303342190.011
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.010
olfactory learningGO:000835520.010
translationGO:0006412930.010
skeletal system morphogenesisGO:00487052030.010
purine nucleotide biosynthetic processGO:0006164650.010
regulation of cell adhesionGO:00301551540.010
positive regulation of protein serine threonine kinase activityGO:00719021060.010
extrinsic apoptotic signaling pathwayGO:00971911260.010
peptidyl tyrosine modificationGO:00182121450.010
synaptic vesicle endocytosisGO:0048488190.010
positive regulation of hydrolase activityGO:00513451480.010
meiotic nuclear divisionGO:00071261150.010
organ growthGO:00352651170.010
production of molecular mediator of immune responseGO:00024401030.010
regulation of peptide transportGO:0090087910.010
regulation of extent of cell growthGO:0061387520.010
acetate ester transportGO:190137420.010
ribonucleotide biosynthetic processGO:0009260590.010
cellular macromolecule catabolic processGO:00442652060.010
visual behaviorGO:0007632450.010
body morphogenesisGO:0010171450.010
peptidyl tyrosine phosphorylationGO:00181081430.010
nucleoside phosphate biosynthetic processGO:1901293790.010
fibroblast growth factor receptor signaling pathwayGO:0008543460.010
regulation of neuron deathGO:19012141340.010

Bace1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.034
nervous system diseaseDOID:86300.034
disease of metabolismDOID:001466700.028
central nervous system diseaseDOID:33100.027
acquired metabolic diseaseDOID:006015800.025
cancerDOID:16200.019
disease of cellular proliferationDOID:1456600.019
neurodegenerative diseaseDOID:128900.017
organ system cancerDOID:005068600.017
disease of mental healthDOID:15000.014
musculoskeletal system diseaseDOID:1700.013
muscle tissue diseaseDOID:6600.012
myopathyDOID:42300.012
muscular diseaseDOID:008000000.012
connective tissue diseaseDOID:6500.010
bone diseaseDOID:008000100.010