Mus musculus

0 known processes

Bace2

beta-site APP-cleaving enzyme 2

(Aliases: ASP21,DRAP,BAE2,1110059C24Rik,AI850424,CEAP1,AEPLC,CDA13,ARP1,ALP56)

Bace2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amine metabolic processGO:0044106440.095
cellular amino acid metabolic processGO:00065201030.081
regulation of cellular ketone metabolic processGO:0010565660.080
cellular ketone metabolic processGO:0042180840.078
amine metabolic processGO:0009308450.078
regulation of cellular amino acid metabolic processGO:000652150.072
regulation of cellular amine metabolic processGO:0033238200.071
positive regulation of cellular amine metabolic processGO:003324050.070
positive regulation of cellular amino acid metabolic processGO:004576430.069
regulation of defense responseGO:00313472330.060
cytokine productionGO:00018163190.055
immune effector processGO:00022523210.054
male gamete generationGO:00482322850.046
protein maturationGO:00516041760.044
negative regulation of cell proliferationGO:00082852960.042
negative regulation of phosphate metabolic processGO:00459361840.042
negative regulation of protein metabolic processGO:00512482820.040
Human
spermatogenesisGO:00072832840.040
peptidyl amino acid modificationGO:00181933360.038
cellular lipid metabolic processGO:00442553230.038
regulation of protein localizationGO:00328802310.036
cation transportGO:00068123990.035
regulation of hormone levelsGO:00108172110.034
negative regulation of molecular functionGO:00440922580.034
heterocycle catabolic processGO:00467002800.033
organic cyclic compound catabolic processGO:19013612950.033
regulation of cytokine productionGO:00018172660.033
cell adhesionGO:00071553290.032
glycoprotein metabolic processGO:00091001160.032
Human
regulation of secretionGO:00510462740.031
negative regulation of cellular protein metabolic processGO:00322692470.031
purine containing compound metabolic processGO:00725213110.031
apoptotic signaling pathwayGO:00971903060.030
positive regulation of protein modification processGO:00314012990.029
negative regulation of phosphorylationGO:00423261660.029
protein processingGO:00164851630.029
oxidation reduction processGO:00551143420.029
ras protein signal transductionGO:0007265770.029
aromatic compound catabolic processGO:00194392860.028
small gtpase mediated signal transductionGO:0007264970.028
nucleoside phosphate metabolic processGO:00067533380.028
cell recognitionGO:0008037830.027
regulation of hydrolase activityGO:00513362460.026
regulation of secretion by cellGO:19035302490.026
mapk cascadeGO:00001652810.026
response to molecule of bacterial originGO:00022371430.026
negative regulation of phosphorus metabolic processGO:00105631840.025
rho protein signal transductionGO:0007266320.025
response to organonitrogen compoundGO:00102432460.025
negative regulation of lymphocyte activationGO:0051250910.024
extracellular structure organizationGO:00430621480.024
lipid biosynthetic processGO:00086101790.024
carbohydrate metabolic processGO:00059752300.024
intracellular protein transportGO:00068862040.024
nucleoside catabolic processGO:00091642060.024
lymphocyte mediated immunityGO:00024491390.024
nitrogen compound transportGO:00717052710.023
carbohydrate derivative biosynthetic processGO:19011371830.023
Human
regulation of cell activationGO:00508652890.023
regulation of multi organism processGO:00439001110.023
cell type specific apoptotic processGO:00972852680.023
regulation of t cell activationGO:00508631700.023
positive regulation of nervous system developmentGO:00519622210.023
regulation of mapk cascadeGO:00434082480.023
developmental maturationGO:00217001930.022
blood circulationGO:00080151950.022
regulation of protein maturationGO:1903317960.022
cellular nitrogen compound catabolic processGO:00442702800.022
respiratory system developmentGO:00605411900.022
skeletal system developmentGO:00015013560.021
organonitrogen compound biosynthetic processGO:19015661920.021
renal system developmentGO:00720012250.021
regulation of cell motilityGO:20001452360.021
ribose phosphate metabolic processGO:00196932910.021
nucleobase containing small molecule metabolic processGO:00550863520.021
positive regulation of secretionGO:00510471300.021
purine nucleotide metabolic processGO:00061633020.021
purine nucleotide catabolic processGO:00061952110.021
peptide secretionGO:00027901140.021
negative regulation of immune system processGO:00026832090.021
nucleoside triphosphate metabolic processGO:00091412300.021
positive regulation of protein phosphorylationGO:00019342420.021
nucleotide metabolic processGO:00091173320.021
response to organic cyclic compoundGO:00140701980.021
striated muscle tissue developmentGO:00147062930.020
cellular response to lipidGO:00713961450.020
leukocyte mediated immunityGO:00024431740.020
regulation of intracellular transportGO:00323861590.020
regulation of establishment of protein localizationGO:00702011810.020
cellular homeostasisGO:00197252400.020
purine ribonucleoside triphosphate metabolic processGO:00092052200.019
organelle fissionGO:00482851700.019
glycosyl compound metabolic processGO:19016572460.019
purine ribonucleoside triphosphate catabolic processGO:00092071990.019
inflammatory responseGO:00069542440.019
cellular response to hormone stimulusGO:00328701500.019
response to growth factorGO:00708481980.019
organonitrogen compound catabolic processGO:19015652640.019
nucleoside phosphate catabolic processGO:19012922220.019
macromolecule catabolic processGO:00090572810.019
epithelial tube morphogenesisGO:00605623030.019
negative regulation of multi organism processGO:0043901680.019
endocytosisGO:00068971680.019
regulation of protein transportGO:00512231630.019
hematopoietic progenitor cell differentiationGO:00022441430.019
regulation of membrane potentialGO:00423911920.019
regulation of organelle organizationGO:00330432890.018
purine ribonucleoside metabolic processGO:00461282410.018
regulation of lymphocyte activationGO:00512492400.018
regulation of kinase activityGO:00435492490.018
posttranscriptional regulation of gene expressionGO:00106081550.018
sulfur compound metabolic processGO:00067901000.018
amide transportGO:00428861380.018
ribonucleoside metabolic processGO:00091192450.018
regulation of transferase activityGO:00513382630.018
purine ribonucleoside catabolic processGO:00461302050.018
regulation of cell migrationGO:00303342190.018
angiogenesisGO:00015252010.018
protein localization to organelleGO:00333651850.017
g protein coupled receptor signaling pathwayGO:00071862430.017
regulation of response to woundingGO:19030341890.017
defense response to bacteriumGO:00427421190.017
cellular response to organonitrogen compoundGO:00714171450.017
rhythmic processGO:00485111740.017
respiratory tube developmentGO:00303231670.017
peptidyl tyrosine phosphorylationGO:00181081430.017
glucose homeostasisGO:00425931280.017
nucleotide catabolic processGO:00091662170.017
t cell activationGO:00421102890.017
organophosphate catabolic processGO:00464342320.017
positive regulation of mapk cascadeGO:00434101700.017
ribonucleotide metabolic processGO:00092592910.016
negative regulation of cellular amine metabolic processGO:003323910.016
response to inorganic substanceGO:0010035960.016
cytoplasmic transportGO:00164822340.016
purine nucleoside triphosphate metabolic processGO:00091442260.016
response to acid chemicalGO:00011011110.016
regulation of protein processingGO:0070613960.016
lung developmentGO:00303241640.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.016
transmembrane transportGO:00550854120.016
regulation of proteolysisGO:00301621640.016
intrinsic apoptotic signaling pathwayGO:00971931320.016
cellular response to biotic stimulusGO:0071216920.016
leukocyte differentiationGO:00025213420.016
negative regulation of cell activationGO:00508661110.016
ribonucleoside triphosphate metabolic processGO:00091992200.016
purine nucleoside catabolic processGO:00061522050.016
ossificationGO:00015032160.016
chemotaxisGO:00069352470.016
production of molecular mediator of immune responseGO:00024401030.016
extracellular matrix organizationGO:00301981470.016
response to lipopolysaccharideGO:00324961280.016
muscle system processGO:00030121410.016
cellular response to cytokine stimulusGO:00713451890.016
cell maturationGO:00484691270.016
circadian rhythmGO:00076231140.015
cytokine secretionGO:0050663720.015
purine nucleoside metabolic processGO:00422782410.015
defense response to other organismGO:00985421970.015
positive regulation of cell deathGO:00109422240.015
carbohydrate derivative catabolic processGO:19011362310.015
activation of immune responseGO:00022531380.015
ribonucleoside catabolic processGO:00424542060.015
organic hydroxy compound metabolic processGO:19016152030.015
skin developmentGO:00435882200.015
monocarboxylic acid metabolic processGO:00327871910.015
bone developmentGO:00603481200.015
midgut developmentGO:000749440.015
purine ribonucleotide metabolic processGO:00091502900.015
wound healingGO:00420601570.015
regulation of cell projection organizationGO:00313442060.015
adaptive immune responseGO:00022501550.015
innate immune responseGO:00450871570.015
development of primary sexual characteristicsGO:00451371430.015
ribonucleoside triphosphate catabolic processGO:00092031990.015
morphogenesis of a branching structureGO:00017632030.015
mitotic cell cycleGO:00002781950.015
t cell mediated immunityGO:0002456500.015
divalent metal ion transportGO:00708381720.015
single organism cell adhesionGO:00986021560.014
regulation of cell adhesionGO:00301551540.014
gland developmentGO:00487323300.014
alpha beta t cell activationGO:0046631910.014
alcohol metabolic processGO:00060661160.014
ribonucleotide catabolic processGO:00092612080.014
regionalizationGO:00030023370.014
fatty acid metabolic processGO:00066311210.014
hormone metabolic processGO:0042445860.014
protein modification by small protein conjugation or removalGO:00706472070.014
regulation of cell cycleGO:00517262810.014
regulation of protein secretionGO:0050708820.014
macromolecule glycosylationGO:0043413550.014
regulation of epithelial cell proliferationGO:00506781410.014
germ cell developmentGO:00072811850.014
regulation of anatomical structure sizeGO:00900661780.014
negative regulation of cellular amino acid metabolic processGO:004576300.014
detection of stimulusGO:0051606840.014
regulation of system processGO:00440572000.014
hormone secretionGO:00468791280.014
negative regulation of protein phosphorylationGO:00019331260.014
antimicrobial peptide biosynthetic processGO:000277720.014
regulation of lipid metabolic processGO:00192161180.014
nucleoside metabolic processGO:00091162460.014
branching morphogenesis of an epithelial tubeGO:00487541590.014
carbohydrate homeostasisGO:00335001280.014
ion transmembrane transportGO:00342203610.014
connective tissue developmentGO:00614481790.014
cell substrate adhesionGO:00315891300.014
immune response regulating signaling pathwayGO:00027641250.014
cellular response to growth factor stimulusGO:00713631970.013
extrinsic apoptotic signaling pathwayGO:00971911260.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.013
regulation of cytoplasmic transportGO:19036491120.013
negative regulation of hydrolase activityGO:0051346710.013
purine nucleoside triphosphate catabolic processGO:00091462030.013
divalent inorganic cation transportGO:00725111780.013
purine ribonucleotide catabolic processGO:00091542080.013
circulatory system processGO:00030131970.013
peptidyl tyrosine modificationGO:00182121450.013
glycoprotein biosynthetic processGO:0009101890.013
Human
lymphocyte proliferationGO:00466511640.013
positive regulation of intracellular transportGO:0032388700.013
negative regulation of protein processingGO:0010955790.013
positive regulation of secretion by cellGO:19035321140.013
organ growthGO:00352651170.013
protein secretionGO:00093061110.013
negative regulation of cellular component organizationGO:00511291940.013
carboxylic acid biosynthetic processGO:0046394860.013
wnt signaling pathwayGO:00160551880.013
epithelial cell proliferationGO:00506731740.013
peptidyl serine modificationGO:0018209830.013
organelle localizationGO:00516401790.013
lymphocyte differentiationGO:00300982420.013
organic acid biosynthetic processGO:0016053860.013
nucleoside triphosphate catabolic processGO:00091432050.013
glycosylationGO:0070085620.013
cellular response to organic cyclic compoundGO:0071407870.013
regulation of t cell proliferationGO:0042129920.013
nuclear divisionGO:00002801580.013
negative regulation of protein maturationGO:1903318790.013
meiotic cell cycleGO:00513211220.013
positive regulation of protein transportGO:0051222930.013
cation transmembrane transportGO:00986552660.012
positive regulation of programmed cell deathGO:00430682180.012
gonad developmentGO:00084061410.012
muscle tissue developmentGO:00605373080.012
establishment of blood nerve barrierGO:000806530.012
compound eye developmentGO:004874910.012
regulation of neuron differentiationGO:00456642810.012
protein glycosylationGO:0006486550.012
regulation of leukocyte proliferationGO:00706631210.012
multicellular organismal homeostasisGO:00488711640.012
meiotic cell cycle processGO:1903046770.012
muscle cell differentiationGO:00426922610.012
regulation of protein serine threonine kinase activityGO:00719001570.012
regulation of vesicle mediated transportGO:00606271390.012
reactive oxygen species metabolic processGO:0072593840.012
microtubule based processGO:00070172360.012
peptide transportGO:00158331330.012
cellular response to lipopolysaccharideGO:0071222770.012
protein ubiquitinationGO:00165671710.012
blood vessel morphogenesisGO:00485142850.012
cellular macromolecule catabolic processGO:00442652060.012
fertilizationGO:00095661270.012
protein modification by small protein conjugationGO:00324461870.012
positive regulation of apoptotic processGO:00430652170.012
cell killingGO:0001906670.012
striated muscle myosin thick filament assemblyGO:007168810.012
interleukin 8 productionGO:003263740.012
regulation of vasculature developmentGO:1901342880.012
regulation of peptidase activityGO:0052547960.012
purine containing compound catabolic processGO:00725232130.012
positive regulation of transferase activityGO:00513471670.012
regulation of peptidyl tyrosine phosphorylationGO:0050730930.012
sensory perceptionGO:00076002450.012
regulation of interleukin 8 productionGO:003267730.012
microtubule cytoskeleton organizationGO:00002261570.012
symbiosis encompassing mutualism through parasitismGO:0044403830.012
negative regulation of proteolysisGO:0045861740.012
chromatin modificationGO:00165681870.012
cellular protein complex assemblyGO:00436231160.012
glycosyl compound catabolic processGO:19016582060.012
mitochondrion organizationGO:00070051340.012
nucleocytoplasmic transportGO:00069131390.012
neuron deathGO:00709971540.012
leukocyte mediated cytotoxicityGO:0001909620.012
negative regulation of protein modification processGO:00314001630.012
regulation of gtp catabolic processGO:00331241130.011
positive regulation of cell developmentGO:00107202370.011
cellular chemical homeostasisGO:00550822150.011
regulation of cellular component sizeGO:00325351210.011
histone modificationGO:00165701590.011
regulation of angiotensin metabolic processGO:006017740.011
dna metabolic processGO:00062593030.011
positive regulation of immune effector processGO:00026991070.011
membrane organizationGO:00610242450.011
positive regulation of protein kinase activityGO:00458601440.011
positive regulation of hydrolase activityGO:00513451480.011
regulation of endopeptidase activityGO:0052548890.011
meiotic nuclear divisionGO:00071261150.011
homeostasis of number of cellsGO:00488722100.011
skeletal system morphogenesisGO:00487052030.011
actin cytoskeleton organizationGO:00300362200.011
morphogenesis of embryonic epitheliumGO:00163311590.011
negative regulation of t cell activationGO:0050868650.011
leukocyte proliferationGO:00706611720.011
regulation of cellular catabolic processGO:00313292420.011
single organismal cell cell adhesionGO:00163371310.011
positive regulation of cytokine productionGO:00018191740.011
regulation of nucleotide metabolic processGO:00061401690.011
regulation of reactive oxygen species metabolic processGO:2000377400.011
multicellular organism growthGO:00352641610.011
regulation of angiogenesisGO:0045765810.011
regulation of cellular component biogenesisGO:00440871810.011
camera type eye developmentGO:00430102660.011
biomineral tissue developmentGO:0031214640.011
protein catabolic processGO:00301632210.011
nuclear transportGO:00511691390.011
regulation of apoptotic signaling pathwayGO:20012331970.011
embryonic organ morphogenesisGO:00485622760.011
transmission of nerve impulseGO:0019226760.011
positive regulation of apoptotic signaling pathwayGO:2001235950.011
defecationGO:003042110.011
response to peptide hormoneGO:00434341270.011
anatomical structure homeostasisGO:00602491450.011
mitotic cytokinesisGO:000028140.011
inorganic ion transmembrane transportGO:00986602340.011
cellular response to molecule of bacterial originGO:0071219830.011
regulation of purine nucleotide catabolic processGO:00331211220.011
negative regulation of intracellular signal transductionGO:19025321670.011
negative regulation of cell cycleGO:00457861230.011
covalent chromatin modificationGO:00165691630.011
regulation of bindingGO:00510981110.011
inorganic cation transmembrane transportGO:00986622070.011
cellular response to dna damage stimulusGO:00069742070.010
cellular metal ion homeostasisGO:00068751510.010
cellular response to insulin stimulusGO:0032869780.010
response to oxygen levelsGO:0070482620.010
synapse organizationGO:00508081250.010
neuronal action potentialGO:0019228540.010
positive regulation of kinase activityGO:00336741550.010
negative regulation of peptidase activityGO:0010466460.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.010
heart morphogenesisGO:00030071780.010
interspecies interaction between organismsGO:0044419830.010
forebrain developmentGO:00309003020.010
regulation of protein kinase activityGO:00458592320.010
negative regulation of cellular response to growth factor stimulusGO:0090288460.010
spermatid differentiationGO:00485151150.010
regulation of organ morphogenesisGO:20000271440.010
cation homeostasisGO:00550802120.010
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.010
regulation of inflammatory responseGO:00507271470.010
nephron developmentGO:00720061090.010
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.010
regulation of cytoskeleton organizationGO:00514931220.010
action potentialGO:0001508780.010
telencephalon developmentGO:00215371860.010
bmp signaling pathwayGO:0030509930.010
tissue homeostasisGO:00018941150.010
t cell proliferationGO:00420981200.010

Bace2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
nervous system diseaseDOID:86300.030
disease of metabolismDOID:001466700.018
sensory system diseaseDOID:005015500.016
retinal diseaseDOID:567900.013
eye diseaseDOID:561400.013
retinal degenerationDOID:846600.013
eye and adnexa diseaseDOID:149200.013
central nervous system diseaseDOID:33100.012
musculoskeletal system diseaseDOID:1700.011
inherited metabolic disorderDOID:65500.011