Mus musculus

0 known processes

Iars

isoleucine-tRNA synthetase

(Aliases: 2510016L12Rik,ILRS,E430001P04Rik,AI327140,AU044614)

Iars biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
amino acid activationGO:004303810.578
Yeast
translationGO:0006412930.526
Yeast
trna aminoacylation for protein translationGO:000641810.476
Yeast
cellular amino acid metabolic processGO:00065201030.470
Yeast
trna aminoacylationGO:004303910.256
Yeast
posttranscriptional regulation of gene expressionGO:00106081550.160
trna metabolic processGO:0006399110.146
Yeast
neuron apoptotic processGO:00514021420.145
regulation of translationGO:0006417710.138
regulation of organelle organizationGO:00330432890.078
folic acid containing compound metabolic processGO:000676030.069
nucleobase containing small molecule metabolic processGO:00550863520.068
ribonucleoprotein complex disassemblyGO:003298830.067
protein import into nucleusGO:0006606950.064
cellular amine metabolic processGO:0044106440.060
organelle disassemblyGO:190300820.059
amine metabolic processGO:0009308450.059
response to oxidative stressGO:00069791230.054
cytoplasmic transportGO:00164822340.053
establishment of organelle localizationGO:00516561220.047
macromolecule methylationGO:00434141200.047
neuron deathGO:00709971540.041
organelle localizationGO:00516401790.039
cellular protein complex assemblyGO:00436231160.036
negative regulation of neuron deathGO:1901215980.035
hematopoietic progenitor cell differentiationGO:00022441430.032
negative regulation of cellular protein metabolic processGO:00322692470.031
cellular nitrogen compound catabolic processGO:00442702800.031
cellular response to cytokine stimulusGO:00713451890.030
methylationGO:00322591340.030
metaphase plate congressionGO:005131020.029
nucleocytoplasmic transportGO:00069131390.029
regulation of neuron apoptotic processGO:00435231220.028
establishment of protein localization to organelleGO:00725941180.027
regulation of protein localizationGO:00328802310.027
membrane organizationGO:00610242450.027
protein importGO:00170381010.026
circadian rhythmGO:00076231140.026
multicellular organismal homeostasisGO:00488711640.026
regulation of cellular amine metabolic processGO:0033238200.025
nuclear transportGO:00511691390.025
regulation of neuron deathGO:19012141340.024
negative regulation of neuron apoptotic processGO:0043524920.024
apoptotic signaling pathwayGO:00971903060.024
carbohydrate derivative catabolic processGO:19011362310.023
epidermis developmentGO:00085441870.023
regulation of cell cycleGO:00517262810.023
mitochondrial translationGO:003254340.022
organophosphate biosynthetic processGO:00904071220.022
regulation of exit from mitosisGO:000709610.022
regulation of cellular component sizeGO:00325351210.022
negative regulation of dna replicationGO:000815640.022
positive regulation of cellular amino acid metabolic processGO:004576430.021
regulation of mitochondrion organizationGO:0010821270.021
nucleoside phosphate metabolic processGO:00067533380.021
mitochondrion organizationGO:00070051340.021
regulation of cellular amino acid metabolic processGO:000652150.021
purine nucleoside triphosphate metabolic processGO:00091442260.020
organic cyclic compound catabolic processGO:19013612950.020
regulation of cytoskeleton organizationGO:00514931220.020
regulation of cellular ketone metabolic processGO:0010565660.019
positive regulation of protein transportGO:0051222930.019
developmental growth involved in morphogenesisGO:00605601380.019
ribosome biogenesisGO:0042254200.019
leukocyte proliferationGO:00706611720.018
nucleotide biosynthetic processGO:0009165780.018
endocytosisGO:00068971680.018
leukocyte differentiationGO:00025213420.018
wound healingGO:00420601570.018
purine nucleoside catabolic processGO:00061522050.018
t cell proliferationGO:00420981200.018
protein targetingGO:00066051430.018
neuromuscular processGO:0050905990.017
organonitrogen compound biosynthetic processGO:19015661920.017
single organism nuclear importGO:1902593950.017
innate immune responseGO:00450871570.017
cell growthGO:00160491300.017
gonad developmentGO:00084061410.017
regulation of establishment of protein localizationGO:00702011810.017
actin cytoskeleton organizationGO:00300362200.017
ribose phosphate metabolic processGO:00196932910.017
protein localization to nucleusGO:00345041210.017
response to amino acidGO:0043200370.017
response to acid chemicalGO:00011011110.016
positive regulation of cellular amine metabolic processGO:003324050.016
myeloid leukocyte differentiationGO:00025731190.016
purine ribonucleotide catabolic processGO:00091542080.016
actin filament organizationGO:00070151130.016
regulation of hydrolase activityGO:00513362460.016
coenzyme metabolic processGO:0006732520.016
regulation of protein bindingGO:0043393600.016
ribonucleoside metabolic processGO:00091192450.016
regulation of protein transportGO:00512231630.015
ribose phosphate biosynthetic processGO:0046390590.015
nucleotide metabolic processGO:00091173320.015
purine ribonucleotide metabolic processGO:00091502900.015
positive regulation of cell activationGO:00508671580.015
cation transmembrane transportGO:00986552660.015
t cell activationGO:00421102890.015
germ cell developmentGO:00072811850.014
negative regulation of cell proliferationGO:00082852960.014
nls bearing protein import into nucleusGO:000660720.014
nucleoside phosphate biosynthetic processGO:1901293790.014
response to organonitrogen compoundGO:00102432460.014
rna processingGO:00063961050.014
nuclear importGO:0051170950.014
regulation of protein localization to nucleusGO:1900180600.014
response to reactive oxygen speciesGO:0000302560.014
ossificationGO:00015032160.014
Human
regulation of intracellular transportGO:00323861590.014
pteridine containing compound metabolic processGO:004255850.014
cellular response to organonitrogen compoundGO:00714171450.014
gene silencing by rnaGO:0031047190.014
muscle tissue developmentGO:00605373080.014
positive regulation of hydrolase activityGO:00513451480.013
negative regulation of molecular functionGO:00440922580.013
cellular protein complex disassemblyGO:0043624360.013
ribonucleoside catabolic processGO:00424542060.013
regulation of intracellular protein transportGO:0033157820.013
negative regulation of protein metabolic processGO:00512482820.013
cellular response to oxidative stressGO:0034599760.013
nuclear divisionGO:00002801580.013
ras protein signal transductionGO:0007265770.013
forebrain developmentGO:00309003020.013
cellular ketone metabolic processGO:0042180840.013
organonitrogen compound catabolic processGO:19015652640.013
microtubule based processGO:00070172360.013
small gtpase mediated signal transductionGO:0007264970.013
cell type specific apoptotic processGO:00972852680.012
cellular response to amino acid stimulusGO:0071230290.012
nucleoside triphosphate metabolic processGO:00091412300.012
positive regulation of protein localization to nucleusGO:1900182300.012
maintenance of locationGO:0051235890.012
positive regulation of translationGO:0045727190.012
glycosyl compound metabolic processGO:19016572460.011
secretory granule organizationGO:0033363200.011
nucleoside catabolic processGO:00091642060.011
regulation of neuron differentiationGO:00456642810.011
intrinsic apoptotic signaling pathwayGO:00971931320.011
maturation of ssu rrnaGO:003049010.011
divalent inorganic cation transportGO:00725111780.011
regulation of secretion by cellGO:19035302490.011
regulation of cellular component biogenesisGO:00440871810.011
mitotic cell cycle processGO:19030471590.011
positive regulation of intracellular protein transportGO:0090316420.011
purine containing compound metabolic processGO:00725213110.011
regulation of membrane potentialGO:00423911920.011
response to inorganic substanceGO:0010035960.011
heterocycle catabolic processGO:00467002800.011
protein alkylationGO:0008213810.011
skin developmentGO:00435882200.011
lymphocyte proliferationGO:00466511640.011
response to endoplasmic reticulum stressGO:0034976530.011
nucleus organizationGO:0006997450.010
dna damage response signal transduction by p53 class mediatorGO:0030330190.010
microtubule cytoskeleton organization involved in mitosisGO:190285040.010
regulation of cell motilityGO:20001452360.010
regulation of tor signalingGO:0032006170.010
purine nucleoside metabolic processGO:00422782410.010
locomotory behaviorGO:00076261950.010
sensory perceptionGO:00076002450.010
molting cycleGO:0042303900.010
ribonucleotide catabolic processGO:00092612080.010

Iars disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.889
neuropathyDOID:87000.889
nervous system diseaseDOID:86300.889
neuromuscular diseaseDOID:44000.256
charcot marie tooth diseaseDOID:1059500.112
charcot marie tooth disease type 2DOID:005053900.049
central nervous system diseaseDOID:33100.017
neurodegenerative diseaseDOID:128900.017
sensory system diseaseDOID:005015500.015