Mus musculus

14 known processes

Ldha

lactate dehydrogenase A

(Aliases: Ldhm,Ldh1,l7R2)

Ldha biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
carbohydrate catabolic processGO:0016052321.000
glycolytic processGO:0006096200.999
pyruvate metabolic processGO:0006090280.997
Mouse
hexose catabolic processGO:001932030.993
cellular aldehyde metabolic processGO:0006081120.939
generation of precursor metabolites and energyGO:00060911030.913
myosin filament organizationGO:003103330.910
carbohydrate metabolic processGO:00059752300.862
hexose metabolic processGO:0019318980.860
carbohydrate phosphorylationGO:0046835150.824
pentose phosphate shuntGO:000609820.817
monocarboxylic acid metabolic processGO:00327871910.799
Mouse
monosaccharide metabolic processGO:00059961060.793
nadph regenerationGO:000674020.745
cellular component assembly involved in morphogenesisGO:00109271390.661
ribose phosphate biosynthetic processGO:0046390590.525
Mouse
purine nucleotide biosynthetic processGO:0006164650.477
Mouse
muscle cell developmentGO:00550011330.466
cellular protein complex assemblyGO:00436231160.465
striated muscle myosin thick filament assemblyGO:007168810.451
carbohydrate derivative biosynthetic processGO:19011371830.432
Mouse
glucose metabolic processGO:0006006920.420
oxidation reduction processGO:00551143420.379
nitrogen compound transportGO:00717052710.322
myosin filament assemblyGO:003103420.319
regulation of translationGO:0006417710.303
nucleoside metabolic processGO:00091162460.283
Mouse
ribonucleoside biosynthetic processGO:0042455210.261
Mouse
atp metabolic processGO:0046034750.259
Mouse
carbohydrate biosynthetic processGO:0016051740.215
purine nucleoside biosynthetic processGO:0042451190.192
Mouse
myotube differentiationGO:00149021050.189
transmembrane transportGO:00550854120.181
negative regulation of cellular protein metabolic processGO:00322692470.180
cellular homeostasisGO:00197252400.180
monosaccharide biosynthetic processGO:0046364440.143
purine nucleoside monophosphate metabolic processGO:0009126810.143
Mouse
response to decreased oxygen levelsGO:0036293590.142
Zebrafish
purine nucleoside monophosphate biosynthetic processGO:000912790.142
Mouse
glucose homeostasisGO:00425931280.140
nucleoside phosphate biosynthetic processGO:1901293790.138
Mouse
hexose biosynthetic processGO:0019319390.133
regulation of hormone levelsGO:00108172110.129
gluconeogenesisGO:0006094390.120
sperm motilityGO:0030317470.116
Mouse
ribose phosphate metabolic processGO:00196932910.116
Mouse
response to organonitrogen compoundGO:00102432460.114
actomyosin structure organizationGO:0031032560.109
cellular amino acid metabolic processGO:00065201030.109
purine nucleotide metabolic processGO:00061633020.100
Mouse
regulation of secretionGO:00510462740.099
development of primary sexual characteristicsGO:00451371430.092
response to nicotineGO:003509460.091
cellular amine metabolic processGO:0044106440.083
muscle cell differentiationGO:00426922610.080
purine nucleoside triphosphate metabolic processGO:00091442260.080
Mouse
positive regulation of apoptotic processGO:00430652170.080
somitogenesisGO:0001756690.079
nucleoside biosynthetic processGO:0009163210.078
Mouse
hormone secretionGO:00468791280.078
nadp metabolic processGO:000673960.073
nucleobase containing small molecule metabolic processGO:00550863520.072
Mouse
purine containing compound metabolic processGO:00725213110.072
Mouse
regulation of coenzyme metabolic processGO:005119640.071
oxidoreduction coenzyme metabolic processGO:0006733160.070
amine metabolic processGO:0009308450.069
response to molecule of bacterial originGO:00022371430.067
mitotic cell cycleGO:00002781950.067
positive regulation of cellular amine metabolic processGO:003324050.065
gonad developmentGO:00084061410.065
response to organic cyclic compoundGO:00140701980.064
insulin secretionGO:0030073890.061
cellular carbohydrate catabolic processGO:0044275150.061
fructose 6 phosphate metabolic processGO:000600210.061
mitochondrion organizationGO:00070051340.060
positive regulation of cellular amino acid metabolic processGO:004576430.059
leukocyte proliferationGO:00706611720.058
alpha amino acid metabolic processGO:1901605590.058
purine ribonucleoside metabolic processGO:00461282410.058
Mouse
myofibril assemblyGO:0030239340.056
regulation of cofactor metabolic processGO:005119350.055
cellular amide metabolic processGO:0043603580.054
translationGO:0006412930.053
mesoderm formationGO:0001707620.052
nucleotide metabolic processGO:00091173320.051
Mouse
negative regulation of protein metabolic processGO:00512482820.051
cell redox homeostasisGO:004545460.051
maintenance of locationGO:0051235890.050
cellular response to organonitrogen compoundGO:00714171450.050
regulation of glycolytic processGO:0006110100.049
positive regulation of peptide secretionGO:0002793330.048
cation transportGO:00068123990.048
organophosphate biosynthetic processGO:00904071220.047
Mouse
cofactor metabolic processGO:0051186800.045
purine nucleoside triphosphate biosynthetic processGO:000914570.045
Mouse
regulation of cell cycleGO:00517262810.044
inorganic cation transmembrane transportGO:00986622070.043
response to lipopolysaccharideGO:00324961280.043
cytoplasmic transportGO:00164822340.043
response to oxidative stressGO:00069791230.042
regulation of peptide transportGO:0090087910.042
organic hydroxy compound biosynthetic processGO:1901617770.042
Mouse
positive regulation of hormone secretionGO:0046887380.042
regulation of cellular amino acid metabolic processGO:000652150.040
cristae formationGO:004240730.040
regulation of cellular ketone metabolic processGO:0010565660.040
purine ribonucleoside monophosphate metabolic processGO:0009167800.040
Mouse
cytokine productionGO:00018163190.040
formation of primary germ layerGO:0001704770.039
organic hydroxy compound metabolic processGO:19016152030.039
Mouse
regulation of membrane potentialGO:00423911920.039
regulation of phosphatidylcholine biosynthetic processGO:200124520.038
multicellular organismal agingGO:0010259240.038
ion transmembrane transportGO:00342203610.038
skin developmentGO:00435882200.037
apoptotic signaling pathwayGO:00971903060.036
genitalia developmentGO:0048806370.036
regulation of cell activationGO:00508652890.036
regulation of cellular amine metabolic processGO:0033238200.035
carbohydrate homeostasisGO:00335001280.034
negative regulation of cell cycle phase transitionGO:1901988480.034
placenta developmentGO:00018901400.032
regulation of cellular catabolic processGO:00313292420.032
pyridine nucleotide biosynthetic processGO:001936340.032
protein targetingGO:00066051430.031
homeostasis of number of cellsGO:00488722100.031
alcohol metabolic processGO:00060661160.031
glycosyl compound biosynthetic processGO:1901659210.031
Mouse
negative regulation of peptide secretionGO:0002792160.030
cation transmembrane transportGO:00986552660.028
positive regulation of hydrolase activityGO:00513451480.028
pyridine containing compound metabolic processGO:0072524140.028
metal ion homeostasisGO:00550651890.028
peptidyl amino acid modificationGO:00181933360.028
purine ribonucleotide catabolic processGO:00091542080.028
nucleoside triphosphate metabolic processGO:00091412300.028
Mouse
cellular lipid metabolic processGO:00442553230.028
purine ribonucleotide biosynthetic processGO:0009152590.027
Mouse
energy derivation by oxidation of organic compoundsGO:0015980770.027
lipid localizationGO:00108761260.027
t cell activationGO:00421102890.027
organonitrogen compound biosynthetic processGO:19015661920.026
Mouse
cellular carbohydrate metabolic processGO:00442621190.026
spermatogenesisGO:00072832840.026
regulation of glucose metabolic processGO:0010906600.026
purine nucleoside metabolic processGO:00422782410.026
Mouse
regulation of reactive oxygen species biosynthetic processGO:190342620.026
apoptotic mitochondrial changesGO:0008637480.026
peptidyl proline hydroxylationGO:001951130.026
regulation of carbohydrate metabolic processGO:0006109750.025
nucleoside phosphate metabolic processGO:00067533380.025
Mouse
purine ribonucleoside triphosphate metabolic processGO:00092052200.025
Mouse
lymphocyte proliferationGO:00466511640.025
protein catabolic processGO:00301632210.025
positive regulation of cell deathGO:00109422240.025
pigmentationGO:0043473710.024
ribonucleotide metabolic processGO:00092592910.024
Mouse
muscle system processGO:00030121410.024
striated muscle cell developmentGO:00550021250.024
muscle cell cellular homeostasisGO:0046716120.023
mitotic cell cycle checkpointGO:0007093310.023
regulation of mitotic cell cycleGO:00073461260.023
cell type specific apoptotic processGO:00972852680.023
anatomical structure homeostasisGO:00602491450.022
epithelial tube morphogenesisGO:00605623030.022
regulation of lymphocyte activationGO:00512492400.022
response to heatGO:0009408270.022
neuron deathGO:00709971540.022
locomotory behaviorGO:00076261950.022
pyridine nucleotide metabolic processGO:0019362120.021
amide transportGO:00428861380.021
cation homeostasisGO:00550802120.021
regulation of secretion by cellGO:19035302490.021
cellular ketone metabolic processGO:0042180840.021
regulation of cytokine productionGO:00018172660.021
regulation of hydrolase activityGO:00513362460.021
regulation of cell cycle phase transitionGO:1901987770.021
cellular modified amino acid metabolic processGO:0006575630.021
regulation of transferase activityGO:00513382630.021
cellular response to cytokine stimulusGO:00713451890.021
regulation of nucleoside metabolic processGO:00091181300.020
t cell proliferationGO:00420981200.020
organic acid transportGO:00158491010.020
cellular ion homeostasisGO:00068731650.020
somite developmentGO:0061053810.020
nucleotide biosynthetic processGO:0009165780.020
Mouse
axonogenesisGO:00074092740.020
syncytium formationGO:0006949430.020
regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activityGO:003158520.020
organic hydroxy compound transportGO:0015850930.019
neural tube formationGO:00018411080.019
regulation of t cell activationGO:00508631700.019
regulation of protein localizationGO:00328802310.019
regulation of metal ion transportGO:00109591060.019
positive regulation of insulin secretionGO:0032024260.019
response to estrogenGO:0043627240.019
glycerolipid metabolic processGO:00464861220.019
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.019
intrinsic apoptotic signaling pathwayGO:00971931320.019
segmentationGO:0035282930.019
g protein coupled receptor signaling pathwayGO:00071862430.019
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.019
spermatid differentiationGO:00485151150.018
posttranscriptional regulation of gene expressionGO:00106081550.018
regulation of leukocyte proliferationGO:00706631210.018
cellular response to dna damage stimulusGO:00069742070.018
potassium ion transportGO:0006813520.018
positive regulation of programmed cell deathGO:00430682180.018
purine ribonucleoside monophosphate biosynthetic processGO:000916890.018
Mouse
male gamete generationGO:00482322850.018
epithelial cell developmentGO:00020641590.018
ribonucleoside monophosphate biosynthetic processGO:000915690.018
Mouse
regulation of protein kinase activityGO:00458592320.018
negative regulation of cell cycleGO:00457861230.018
positive regulation of protein modification processGO:00314012990.017
extracellular matrix organizationGO:00301981470.017
reactive oxygen species biosynthetic processGO:190340980.017
inorganic ion transmembrane transportGO:00986602340.017
developmental maturationGO:00217001930.017
oxygen homeostasisGO:003236420.017
purine ribonucleoside triphosphate biosynthetic processGO:000920660.017
Mouse
negative regulation of cell proliferationGO:00082852960.017
circadian regulation of gene expressionGO:0032922480.017
transition metal ion homeostasisGO:0055076540.017
b cell activationGO:00421131610.017
actin cytoskeleton organizationGO:00300362200.017
anion transportGO:00068201770.017
reactive nitrogen species metabolic processGO:200105700.017
ras protein signal transductionGO:0007265770.017
epidermis developmentGO:00085441870.017
response to inorganic substanceGO:0010035960.017
reactive oxygen species metabolic processGO:0072593840.016
respiratory system developmentGO:00605411900.016
ribonucleotide biosynthetic processGO:0009260590.016
Mouse
phospholipid metabolic processGO:0006644870.016
learning or memoryGO:00076111480.016
ribonucleoside triphosphate biosynthetic processGO:000920160.016
Mouse
rhythmic processGO:00485111740.016
regulation of phospholipid biosynthetic processGO:007107130.016
regulation of mapk cascadeGO:00434082480.016
dna metabolic processGO:00062593030.016
cellular response to lipidGO:00713961450.016
regulation of protein serine threonine kinase activityGO:00719001570.016
organic anion transportGO:00157111370.016
protein polymerizationGO:0051258570.016
protein modification by small protein conjugationGO:00324461870.016
ribonucleoside catabolic processGO:00424542060.016
immune response regulating signaling pathwayGO:00027641250.016
response to acid chemicalGO:00011011110.016
protein ubiquitinationGO:00165671710.016
nicotinamide nucleotide metabolic processGO:0046496120.016
purine ribonucleotide metabolic processGO:00091502900.016
Mouse
myeloid cell homeostasisGO:00022621140.016
regulation of organelle organizationGO:00330432890.016
epithelial cell proliferationGO:00506731740.016
negative regulation of neuron deathGO:1901215980.015
cellular divalent inorganic cation homeostasisGO:00725031270.015
regulation of endopeptidase activityGO:0052548890.015
regulation of defense responseGO:00313472330.015
regulation of cysteine type endopeptidase activityGO:2000116650.015
pyridine containing compound catabolic processGO:007252640.015
carboxylic acid biosynthetic processGO:0046394860.015
Mouse
regulation of ion transportGO:00432692150.015
negative regulation of cell cycle processGO:0010948690.015
nucleoside monophosphate metabolic processGO:0009123850.015
Mouse
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.015
leukocyte differentiationGO:00025213420.015
lateral inhibitionGO:004633110.015
negative regulation of intracellular signal transductionGO:19025321670.015
4 hydroxyproline metabolic processGO:001947150.015
striated muscle contractionGO:0006941450.015
aromatic compound catabolic processGO:00194392860.014
fat cell differentiationGO:00454441600.014
cellular response to hormone stimulusGO:00328701500.014
negative regulation of cellular amine metabolic processGO:003323910.014
carbohydrate derivative catabolic processGO:19011362310.014
positive regulation of reactive oxygen species metabolic processGO:2000379110.014
protein oligomerizationGO:0051259670.014
peptide hormone secretionGO:00300721090.014
second messenger mediated signalingGO:0019932730.014
regulation of fat cell differentiationGO:0045598810.014
regionalizationGO:00030023370.014
organelle assemblyGO:00709251770.014
lymphocyte differentiationGO:00300982420.014
regulation of proteolysisGO:00301621640.013
response to steroid hormoneGO:0048545560.013
sensory perceptionGO:00076002450.013
heterocycle catabolic processGO:00467002800.013
activation of immune responseGO:00022531380.013
positive regulation of nucleoside metabolic processGO:0045979910.013
protein processingGO:00164851630.013
positive regulation of protein phosphorylationGO:00019342420.013
phosphatidylethanolamine metabolic processGO:004633720.013
protein modification by small protein conjugation or removalGO:00706472070.013
neuron neuron synaptic transmissionGO:0007270690.013
regulation of transmembrane transportGO:00347621280.013
g2 dna damage checkpointGO:003157280.013
regulation of peptide secretionGO:0002791770.013
organonitrogen compound catabolic processGO:19015652640.013
gas homeostasisGO:003348330.013
cellular response to acid chemicalGO:0071229680.013
regulation of kinase activityGO:00435492490.013
immune response activating signal transductionGO:00027571160.013
monocarboxylic acid biosynthetic processGO:0072330610.013
Mouse
sulfur compound metabolic processGO:00067901000.013
forebrain developmentGO:00309003020.013
negative regulation of translationGO:0017148220.013
cellular metal ion homeostasisGO:00068751510.013
regulation of cellular carbohydrate metabolic processGO:0010675750.013
nicotinamide nucleotide biosynthetic processGO:001935940.013
sensory organ morphogenesisGO:00905962420.013
monocarboxylic acid transportGO:0015718440.012
substantia nigra developmentGO:002176220.012
Human
regulation of apoptotic signaling pathwayGO:20012331970.012
positive regulation of growthGO:00459271040.012
positive regulation of proteolysisGO:0045862850.012
regulation of cellular response to stressGO:00801351590.012
regulation of leukocyte differentiationGO:19021051590.012
innate immune responseGO:00450871570.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.012
proteasomal protein catabolic processGO:0010498980.012
carboxylic acid transportGO:00469421000.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.012
morphogenesis of a branching epitheliumGO:00611381930.012
nuclear transportGO:00511691390.012
myeloid cell differentiationGO:00300992330.012
negative regulation of phosphorus metabolic processGO:00105631840.012
glutamine family amino acid biosynthetic processGO:000908420.012
protein maturationGO:00516041760.012
regulation of neuron apoptotic processGO:00435231220.012
compound eye developmentGO:004874910.012
positive regulation of purine nucleotide metabolic processGO:19005441140.012
mapk cascadeGO:00001652810.011
negative regulation of mammary gland epithelial cell proliferationGO:003360030.011
regulation of receptor activityGO:0010469410.011
respiratory tube developmentGO:00303231670.011
positive regulation of cellular catabolic processGO:00313311480.011
peptidyl tyrosine modificationGO:00182121450.011
regulation of leukocyte apoptotic processGO:2000106560.011
small gtpase mediated signal transductionGO:0007264970.011
dephosphorylationGO:00163111290.011
localization within membraneGO:005166840.011
positive regulation of nucleotide metabolic processGO:00459811140.011
neuronal action potentialGO:0019228540.011
circadian rhythmGO:00076231140.011
positive regulation of cysteine type endopeptidase activityGO:2001056390.011
cellular nitrogen compound catabolic processGO:00442702800.011
regulation of establishment of protein localizationGO:00702011810.011
negative regulation of mitotic cell cycle phase transitionGO:1901991450.011
positive regulation of cell activationGO:00508671580.011
small molecule catabolic processGO:0044282710.011
determination of adult lifespanGO:0008340110.011
activation of cysteine type endopeptidase activityGO:0097202270.011
regulation of nucleotide metabolic processGO:00061401690.011
cellular response to peptide hormone stimulusGO:0071375920.011
peptide transportGO:00158331330.011
mesoderm developmentGO:00074981000.011
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
cellular response to biotic stimulusGO:0071216920.011
divalent metal ion transportGO:00708381720.011
purine containing compound catabolic processGO:00725232130.011
skeletal system developmentGO:00015013560.011
intracellular protein transportGO:00068862040.011
glycerophospholipid metabolic processGO:0006650710.011
regulation of interleukin 8 productionGO:003267730.010
inflammatory responseGO:00069542440.010
positive regulation of transmembrane transportGO:0034764290.010
cellular response to lipopolysaccharideGO:0071222770.010
connective tissue developmentGO:00614481790.010
response to nutrient levelsGO:00316671090.010
renal system developmentGO:00720012250.010
cell adhesionGO:00071553290.010
gland developmentGO:00487323300.010
iron ion homeostasisGO:0055072360.010
defecationGO:003042110.010
cellular response to molecule of bacterial originGO:0071219830.010
divalent inorganic cation transportGO:00725111780.010
regulation of lymphocyte differentiationGO:00456191070.010
divalent inorganic cation homeostasisGO:00725071380.010
chromatin organizationGO:00063252060.010
positive regulation of protein kinase activityGO:00458601440.010

Ldha disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.637
carbohydrate metabolism diseaseDOID:005001300.382
acquired metabolic diseaseDOID:006015800.382
glucose metabolism diseaseDOID:419400.382
disease of anatomical entityDOID:700.082
nervous system diseaseDOID:86300.082
immune system diseaseDOID:291400.062
anemiaDOID:235500.047
hematopoietic system diseaseDOID:7400.047
central nervous system diseaseDOID:33100.017
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014
sensory system diseaseDOID:005015500.012
eye diseaseDOID:561400.012
eye and adnexa diseaseDOID:149200.012
neurodegenerative diseaseDOID:128900.011
organ system cancerDOID:005068600.011
neuropathyDOID:87000.011