Mus musculus

72 known processes

Trim59

tripartite motif-containing 59

(Aliases: 2310035M22Rik,2700022F13Rik,Mrf1,TSBF1)

Trim59 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
meiosis iGO:0007127600.929
meiotic cell cycleGO:00513211220.843
microtubule polymerization or depolymerizationGO:0031109260.733
Mouse
meiotic cell cycle processGO:1903046770.727
microtubule based processGO:00070172360.644
Mouse
organelle fissionGO:00482851700.617
female meiotic divisionGO:0007143210.594
spindle assembly involved in meiosisGO:009030640.551
establishment of organelle localizationGO:00516561220.526
chromosome segregationGO:0007059480.493
mitotic cell cycle processGO:19030471590.424
organelle assemblyGO:00709251770.408
meiotic nuclear divisionGO:00071261150.393
positive regulation of cell divisionGO:0051781310.382
chromosome organization involved in meiosisGO:0070192390.376
mitotic sister chromatid segregationGO:0000070140.363
microtubule cytoskeleton organizationGO:00002261570.360
Mouse
negative regulation of cellular component organizationGO:00511291940.321
Mouse
spindle assembly involved in female meiosisGO:000705630.315
spindle assembly involved in female meiosis iGO:000705720.307
organelle localizationGO:00516401790.292
male gamete generationGO:00482322850.281
spindle assembly involved in mitosisGO:009030740.276
dna metabolic processGO:00062593030.275
regulation of microtubule based processGO:0032886520.273
Mouse
mitotic cytokinesisGO:000028140.266
regulation of centriole replicationGO:004659910.264
negative regulation of cell cycleGO:00457861230.259
regulation of cell cycle processGO:00105641600.245
meiotic chromosome segregationGO:0045132190.238
regulation of mitosisGO:0007088290.238
kinetochore organizationGO:005138320.236
negative regulation of nuclear divisionGO:0051784190.221
nuclear divisionGO:00002801580.209
regulation of cell divisionGO:0051302760.190
mitotic cell cycleGO:00002781950.185
microtubule organizing center organizationGO:0031023280.180
cellular amine metabolic processGO:0044106440.176
regulation of organelle organizationGO:00330432890.175
Mouse
mitotic chromosome condensationGO:000707610.163
development of primary sexual characteristicsGO:00451371430.156
regulation of chromosome organizationGO:0033044830.150
spermatogenesisGO:00072832840.140
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.139
female meiosis iGO:000714470.138
cell divisionGO:00513011200.133
chromatin remodeling at centromereGO:003105520.131
regulation of cytoskeleton organizationGO:00514931220.131
Mouse
attachment of spindle microtubules to kinetochoreGO:000860840.125
regulation of cell cycleGO:00517262810.124
sister chromatid segregationGO:0000819200.122
cellular protein complex disassemblyGO:0043624360.118
Mouse
spindle assemblyGO:0051225130.117
spindle checkpointGO:0031577120.116
mitotic nuclear divisionGO:0007067480.111
regulation of meiosis iGO:006063170.104
regulation of nuclear divisionGO:0051783560.101
negative regulation of meiotic cell cycleGO:0051447140.098
regulation of mitotic cell cycleGO:00073461260.098
negative regulation of organelle organizationGO:0010639900.096
Mouse
germ cell developmentGO:00072811850.094
spermatid developmentGO:00072861080.093
cellular ketone metabolic processGO:0042180840.091
regulation of cellular amino acid metabolic processGO:000652150.091
centromere complex assemblyGO:003450830.091
negative regulation of cellular protein metabolic processGO:00322692470.090
regulation of protein complex disassemblyGO:0043244280.087
Mouse
regulation of cellular amine metabolic processGO:0033238200.085
nucleic acid phosphodiester bond hydrolysisGO:0090305490.085
synapsisGO:0007129340.085
protein complex disassemblyGO:0043241400.084
Mouse
negative regulation of cell divisionGO:0051782240.082
amine metabolic processGO:0009308450.080
cytokinetic processGO:003250620.080
spermatid differentiationGO:00485151150.080
gonad developmentGO:00084061410.080
macromolecule catabolic processGO:00090572810.078
Mouse
male meiosisGO:0007140370.075
gene silencingGO:0016458380.069
cellular protein complex assemblyGO:00436231160.066
negative regulation of microtubule polymerization or depolymerizationGO:0031111150.064
Mouse
positive regulation of nfat protein import into nucleusGO:005153310.063
fertilizationGO:00095661270.063
microtubule cytoskeleton organization involved in mitosisGO:190285040.061
meiotic spindle organizationGO:000021290.061
microtubule nucleationGO:000702020.060
positive regulation of meiosis iGO:006090350.058
cellular macromolecule catabolic processGO:00442652060.056
Mouse
regulation of cell projection organizationGO:00313442060.055
regulation of protein maturationGO:1903317960.052
regulation of cellular catabolic processGO:00313292420.052
protein modification by small protein conjugation or removalGO:00706472070.052
positive regulation of cellular amine metabolic processGO:003324050.052
meiotic cytokinesisGO:003320650.052
negative regulation of cell cycle processGO:0010948690.050
regulation of cellular protein catabolic processGO:1903362610.050
regulation of transferase activityGO:00513382630.049
cytokinesisGO:0000910170.049
neuron migrationGO:00017641220.049
cellular amino acid metabolic processGO:00065201030.049
protein maturationGO:00516041760.048
protein localization to organelleGO:00333651850.048
regulation of cytokinesisGO:003246550.046
regulation of cell cycle phase transitionGO:1901987770.046
cell cycle checkpointGO:0000075470.046
regulation of apoptotic signaling pathwayGO:20012331970.045
centrosome organizationGO:0051297260.045
spindle organizationGO:0007051280.044
negative regulation of chromosome organizationGO:2001251300.044
regulation of neuron differentiationGO:00456642810.044
regulation of microtubule polymerization or depolymerizationGO:0031110200.042
Mouse
dendrite developmentGO:00163581150.042
female meiosis chromosome segregationGO:001632110.042
positive regulation of cell cycle processGO:0090068610.042
apoptotic signaling pathwayGO:00971903060.042
positive regulation of protein modification processGO:00314012990.042
positive regulation of apoptotic processGO:00430652170.041
regulation of mitotic cell cycle phase transitionGO:1901990730.041
modification dependent protein catabolic processGO:00199411330.041
Mouse
nucleocytoplasmic transportGO:00069131390.041
nuclear transportGO:00511691390.040
intracellular protein transportGO:00068862040.040
negative regulation of mitotic cell cycleGO:0045930580.040
protein catabolic processGO:00301632210.040
Mouse
positive regulation of intracellular transportGO:0032388700.039
ribonucleoside triphosphate metabolic processGO:00091992200.039
negative regulation of cellular protein catabolic processGO:1903363220.039
nucleus localizationGO:0051647200.038
wnt signaling pathwayGO:00160551880.038
regulation of cellular ketone metabolic processGO:0010565660.038
negative regulation of mitotic cell cycle phase transitionGO:1901991450.037
nucleotide metabolic processGO:00091173320.037
peptidyl amino acid modificationGO:00181933360.037
cdc42 protein signal transductionGO:003248800.036
hematopoietic progenitor cell differentiationGO:00022441430.036
single fertilizationGO:0007338820.036
female gamete generationGO:0007292740.035
oocyte maturationGO:0001556180.035
regulation of ras protein signal transductionGO:00465781140.034
regulation of nucleocytoplasmic transportGO:0046822730.034
positive regulation of protein phosphorylationGO:00019342420.034
positive regulation of cellular amino acid metabolic processGO:004576430.034
regulation of protein localizationGO:00328802310.033
protein depolymerizationGO:0051261340.033
Mouse
negative regulation of proteolysisGO:0045861740.033
regulation of exit from mitosisGO:000709610.032
centrosome cycleGO:0007098230.032
establishment of spindle localizationGO:0051293190.032
intrinsic apoptotic signaling pathwayGO:00971931320.032
mitotic cell cycle checkpointGO:0007093310.032
regulation of attachment of spindle microtubules to kinetochoreGO:005198830.032
positive regulation of organelle organizationGO:00106381280.031
meiotic chromosome condensationGO:001003230.031
regulation of protein transportGO:00512231630.031
genitalia developmentGO:0048806370.031
positive regulation of nervous system developmentGO:00519622210.031
macromolecular complex disassemblyGO:0032984430.031
Mouse
regulation of intracellular transportGO:00323861590.030
positive regulation of gtp catabolic processGO:0033126850.030
neuroblast proliferationGO:0007405490.030
dna conformation changeGO:0071103370.030
rho protein signal transductionGO:0007266320.030
cellular response to dna damage stimulusGO:00069742070.030
protein localization to nucleusGO:00345041210.030
cell type specific apoptotic processGO:00972852680.029
regulation of chromosome segregationGO:0051983210.029
regulation of neuron projection developmentGO:00109751690.029
cellular protein catabolic processGO:00442571550.028
Mouse
regulation of intracellular protein transportGO:0033157820.028
heterocycle catabolic processGO:00467002800.028
regulation of protein catabolic processGO:00421761080.027
meiosis iiGO:000713570.027
regulation of proteolysisGO:00301621640.027
anion transportGO:00068201770.027
maintenance of locationGO:0051235890.026
regulation of cytoplasmic transportGO:19036491120.026
positive regulation of nucleocytoplasmic transportGO:0046824300.026
receptor mediated endocytosisGO:0006898510.025
negative regulation of cytoskeleton organizationGO:0051494360.025
Mouse
digestive system developmentGO:00551232000.025
negative regulation of metaphase anaphase transition of cell cycleGO:190210080.025
regulation of protein kinase activityGO:00458592320.024
dna ligationGO:000626630.024
double strand break repairGO:0006302480.024
protein polymerizationGO:0051258570.024
negative regulation of sister chromatid segregationGO:003304670.024
negative regulation of protein metabolic processGO:00512482820.024
positive regulation of programmed cell deathGO:00430682180.024
positive regulation of hydrolase activityGO:00513451480.024
single organism nuclear importGO:1902593950.024
negative regulation of protein depolymerizationGO:1901880210.024
Mouse
dna packagingGO:0006323300.024
protein import into nucleusGO:0006606950.024
proteasomal protein catabolic processGO:0010498980.024
Mouse
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051220.023
ubiquitin dependent protein catabolic processGO:00065111290.023
Mouse
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.023
Mouse
regulation of ras gtpase activityGO:0032318880.023
synaptonemal complex assemblyGO:0007130130.023
positive regulation of cellular catabolic processGO:00313311480.023
negative regulation of mitotic sister chromatid segregationGO:003304870.023
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.023
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435150.022
negative regulation of protein complex disassemblyGO:0043242220.022
Mouse
regulation of rho gtpase activityGO:0032319580.022
regulation of cell cycle g2 m phase transitionGO:1902749100.022
astral microtubule organizationGO:003095330.022
endocytosisGO:00068971680.022
positive regulation of protein kinase activityGO:00458601440.022
regulation of dna replicationGO:0006275170.022
positive regulation of cell cycleGO:0045787920.022
actomyosin structure organizationGO:0031032560.021
negative regulation of microtubule depolymerizationGO:0007026130.021
Mouse
centrosome duplicationGO:0051298160.021
ras protein signal transductionGO:0007265770.021
small gtpase mediated signal transductionGO:0007264970.021
aromatic compound catabolic processGO:00194392860.021
regulation of wnt signaling pathwayGO:00301111230.021
metaphase plate congressionGO:005131020.021
rna interferenceGO:001624620.021
protein importGO:00170381010.021
regulation of microtubule depolymerizationGO:0031114130.021
Mouse
negative regulation of molecular functionGO:00440922580.021
dna modificationGO:0006304500.021
nucleobase containing small molecule metabolic processGO:00550863520.020
mitotic spindle assembly checkpointGO:000709470.020
positive regulation of transferase activityGO:00513471670.020
response to oxidative stressGO:00069791230.020
centrosome separationGO:005129940.020
chromosome separationGO:0051304140.020
establishment of protein localization to organelleGO:00725941180.020
negative regulation of cellular catabolic processGO:0031330470.020
dna replicationGO:0006260520.019
ribose phosphate metabolic processGO:00196932910.019
microtubule depolymerizationGO:0007019150.019
Mouse
homeostasis of number of cellsGO:00488722100.019
blood vessel morphogenesisGO:00485142850.019
positive regulation of kinase activityGO:00336741550.019
positive regulation of cell deathGO:00109422240.019
regulation of microtubule cytoskeleton organizationGO:0070507370.019
Mouse
positive regulation of mitotic cell cycleGO:0045931410.019
nitrogen compound transportGO:00717052710.019
dna methylationGO:0006306430.019
regulation of purine nucleotide metabolic processGO:19005421690.019
placenta developmentGO:00018901400.018
regulation of protein processingGO:0070613960.018
regulation of protein import into nucleusGO:0042306520.018
positive regulation of nuclear divisionGO:0051785270.018
negative regulation of mitosisGO:0045839100.018
chromatin modificationGO:00165681870.018
cellular lipid metabolic processGO:00442553230.018
negative regulation of meiotic cell cycle phase transitionGO:190199430.017
negative regulation of mitotic metaphase anaphase transitionGO:004584170.017
regulation of cell activationGO:00508652890.017
negative regulation of cell cycle phase transitionGO:1901988480.017
axonogenesisGO:00074092740.017
male sex differentiationGO:00466611090.016
peptidyl serine phosphorylationGO:0018105740.016
dna repairGO:00062811070.016
methylationGO:00322591340.016
neuron apoptotic processGO:00514021420.016
positive regulation of nucleoside metabolic processGO:0045979910.016
cell fate commitmentGO:00451652100.016
leukocyte differentiationGO:00025213420.016
purine nucleoside metabolic processGO:00422782410.016
establishment or maintenance of cell polarityGO:0007163860.016
respiratory system developmentGO:00605411900.016
heterochromatin organizationGO:007082840.016
developmental maturationGO:00217001930.016
regulation of actin filament based processGO:0032970990.015
protein targetingGO:00066051430.015
regulation of cellular component biogenesisGO:00440871810.015
microtubule based movementGO:0007018840.015
regulation of spindle organizationGO:009022420.015
cellular response to metal ionGO:0071248310.015
regulation of hormone levelsGO:00108172110.015
mrna processingGO:0006397630.015
protein modification by small protein conjugationGO:00324461870.015
negative regulation of mitotic sister chromatid separationGO:200081670.015
cerebral cortex developmentGO:0021987860.015
regulation of protein depolymerizationGO:1901879260.015
Mouse
regulation of kinase activityGO:00435492490.015
mesodermal cell migrationGO:000807840.015
regulation of mitotic metaphase anaphase transitionGO:003007180.015
regulation of mitotic sister chromatid segregationGO:0033047120.015
cell migration involved in gastrulationGO:0042074130.015
b cell differentiationGO:0030183780.014
response to decreased oxygen levelsGO:0036293590.014
cellular response to inorganic substanceGO:0071241370.014
modification dependent macromolecule catabolic processGO:00436321330.014
Mouse
ameboidal type cell migrationGO:00016671280.014
guanosine containing compound catabolic processGO:19010691440.014
myeloid cell differentiationGO:00300992330.014
positive regulation of neuron differentiationGO:00456661410.014
regulation of lipid metabolic processGO:00192161180.014
positive regulation of intracellular protein transportGO:0090316420.014
positive regulation of glycogen catabolic processGO:004581920.014
cytoplasmic transportGO:00164822340.014
deoxyribonucleotide metabolic processGO:0009262140.014
positive regulation of cytoskeleton organizationGO:0051495490.014
protein ubiquitinationGO:00165671710.014
reciprocal dna recombinationGO:0035825160.013
mitotic cell cycle embryonicGO:004544850.013
microtubule polymerizationGO:0046785120.013
development of primary male sexual characteristicsGO:0046546880.013
negative regulation of wnt signaling pathwayGO:0030178730.013
gtp catabolic processGO:00061841430.013
negative regulation of cell activationGO:00508661110.013
negative regulation of protein processingGO:0010955790.013
regulation of cellular response to hypoxiaGO:190003720.013
negative regulation of protein catabolic processGO:0042177360.013
positive regulation of protein transportGO:0051222930.013
forebrain developmentGO:00309003020.013
regulation of hydrolase activityGO:00513362460.013
regulation of nucleotide metabolic processGO:00061401690.013
neural precursor cell proliferationGO:00613511210.013
regulation of meiotic cell cycleGO:0051445340.013
male gonad developmentGO:0008584880.013
actin cytoskeleton organizationGO:00300362200.013
gastrulationGO:00073691160.013
ribonucleoside metabolic processGO:00091192450.013
gtp metabolic processGO:00460391440.013
meiotic dna double strand break formationGO:004213830.013
smoothened signaling pathwayGO:00072241050.012
cellularizationGO:000734910.012
posttranscriptional regulation of gene expressionGO:00106081550.012
protein methylationGO:0006479810.012
positive regulation of cell developmentGO:00107202370.012
positive regulation of purine nucleotide metabolic processGO:19005441140.012
positive regulation of nucleotide catabolic processGO:0030813880.012
neural tube formationGO:00018411080.012
purine ribonucleotide catabolic processGO:00091542080.012
cellular nitrogen compound catabolic processGO:00442702800.012
regulation of homeostatic processGO:00328441820.012
maintenance of dna methylationGO:001021640.012
telencephalon developmentGO:00215371860.012
activation of rac gtpase activityGO:003286320.012
oxidation reduction processGO:00551143420.012
muscle cell differentiationGO:00426922610.012
ovulationGO:0030728150.012
regulation of canonical wnt signaling pathwayGO:0060828820.012
microtubule slidingGO:005101210.012
rna 3 end processingGO:0031123200.012
regulation of protein serine threonine kinase activityGO:00719001570.012
response to hypoxiaGO:0001666580.012
protein processingGO:00164851630.012
negative regulation of phagocytosisGO:005076540.011
b cell activationGO:00421131610.011
nucleoside catabolic processGO:00091642060.011
organic hydroxy compound metabolic processGO:19016152030.011
response to oxygen levelsGO:0070482620.011
muscle tissue developmentGO:00605373080.011
negative regulation of b cell differentiationGO:004557840.011
carbohydrate homeostasisGO:00335001280.011
regulation of centrosome cycleGO:0046605100.011
neuron deathGO:00709971540.011
purine ribonucleoside triphosphate catabolic processGO:00092071990.011
purine nucleoside triphosphate metabolic processGO:00091442260.011
carbohydrate derivative catabolic processGO:19011362310.011
macromolecule methylationGO:00434141200.011
purine containing compound metabolic processGO:00725213110.011
positive regulation of nucleotide metabolic processGO:00459811140.011
membrane organizationGO:00610242450.011
negative regulation of protein maturationGO:1903318790.011
mitotic centrosome separationGO:000710040.011
neural tube closureGO:0001843900.011
cellular response to lipidGO:00713961450.011
Mouse
centriole assemblyGO:009853460.011
multicellular organism growthGO:00352641610.011
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.011
nucleus organizationGO:0006997450.011
negative regulation of cell developmentGO:00107211690.011
regulation of myeloid cell differentiationGO:0045637960.011
nuclear importGO:0051170950.011
synaptonemal complex organizationGO:0070193150.010
microtubule anchoringGO:003445390.010
lymphocyte differentiationGO:00300982420.010
mitotic recombinationGO:000631230.010
heterochromatin assemblyGO:003150720.010
dna recombinationGO:0006310920.010
negative regulation of apoptotic cell clearanceGO:200042610.010
regulation of histone modificationGO:0031056560.010
regulation of leukocyte differentiationGO:19021051590.010
regulation of actin cytoskeleton organizationGO:0032956840.010
dna endoreduplicationGO:004202340.010
response to organic cyclic compoundGO:00140701980.010
Mouse

Trim59 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
physical disorderDOID:008001500.020