Mus musculus

0 known processes

Hspa4

heat shock protein 4

(Aliases: AI317151,Hsp70RY,70kDa,APG-2,Hsp110,KIAA4025,mKIAA4025)

Hspa4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein refoldingGO:004202610.495
Yeast
cellular macromolecule catabolic processGO:00442652060.441
establishment of protein localization to organelleGO:00725941180.350
Human
protein localization to organelleGO:00333651850.238
Human
macromolecule catabolic processGO:00090572810.230
protein importGO:00170381010.199
Human
organelle disassemblyGO:190300820.171
actin cytoskeleton organizationGO:00300362200.154
posttranscriptional regulation of gene expressionGO:00106081550.154
aromatic compound catabolic processGO:00194392860.151
Yeast
cytoplasmic transportGO:00164822340.143
Human
organic cyclic compound catabolic processGO:19013612950.139
Yeast
protein catabolic processGO:00301632210.123
protein localization to nucleusGO:00345041210.121
protein import into nucleusGO:0006606950.119
nuclear transportGO:00511691390.117
myosin filament organizationGO:003103330.116
nucleoside phosphate metabolic processGO:00067533380.115
Yeast
glycosyl compound metabolic processGO:19016572460.112
Yeast
ribose phosphate metabolic processGO:00196932910.110
Yeast
intracellular protein transportGO:00068862040.109
Human
single organism nuclear importGO:1902593950.107
negative regulation of cellular protein metabolic processGO:00322692470.106
Rat
ribonucleoside triphosphate metabolic processGO:00091992200.105
Yeast
nucleoside metabolic processGO:00091162460.102
Yeast
nucleotide catabolic processGO:00091662170.100
Yeast
regulation of cellular catabolic processGO:00313292420.096
striated muscle myosin thick filament assemblyGO:007168810.094
cellular nitrogen compound catabolic processGO:00442702800.091
Yeast
cell adhesionGO:00071553290.088
heterocycle catabolic processGO:00467002800.087
Yeast
organonitrogen compound catabolic processGO:19015652640.087
Yeast
modification dependent protein catabolic processGO:00199411330.086
organelle assemblyGO:00709251770.083
axonogenesisGO:00074092740.081
nucleobase containing small molecule metabolic processGO:00550863520.080
Yeast
nucleocytoplasmic transportGO:00069131390.080
nuclear importGO:0051170950.078
oocyte axis specificationGO:000730920.076
nucleoside catabolic processGO:00091642060.075
Yeast
oocyte anterior posterior axis specificationGO:000731420.075
ubiquitin dependent protein catabolic processGO:00065111290.075
purine nucleotide catabolic processGO:00061952110.075
Yeast
nucleoside phosphate catabolic processGO:19012922220.074
Yeast
ribonucleoside metabolic processGO:00091192450.072
Yeast
mrna metabolic processGO:0016071840.070
purine nucleoside triphosphate metabolic processGO:00091442260.069
Yeast
ribonucleoside triphosphate catabolic processGO:00092031990.067
Yeast
intracellular mrna localizationGO:000829840.066
purine ribonucleotide metabolic processGO:00091502900.065
Yeast
endocytosisGO:00068971680.063
Worm
purine ribonucleoside triphosphate catabolic processGO:00092071990.060
Yeast
regulation of organelle organizationGO:00330432890.059
protein modification by small protein conjugation or removalGO:00706472070.057
protein ubiquitinationGO:00165671710.056
purine nucleoside catabolic processGO:00061522050.056
Yeast
amine metabolic processGO:0009308450.054
purine nucleotide metabolic processGO:00061633020.053
Yeast
ribonucleoside catabolic processGO:00424542060.053
Yeast
proteolysis involved in cellular protein catabolic processGO:00516031470.052
organophosphate catabolic processGO:00464342320.052
Yeast
regulation of intracellular transportGO:00323861590.052
glycosyl compound catabolic processGO:19016582060.051
Yeast
myosin filament assemblyGO:003103420.051
regulation of establishment of protein localizationGO:00702011810.051
carbohydrate derivative catabolic processGO:19011362310.050
Yeast
oocyte constructionGO:000730820.049
modification dependent macromolecule catabolic processGO:00436321330.049
rna interferenceGO:001624620.049
actin filament organizationGO:00070151130.046
purine nucleoside triphosphate catabolic processGO:00091462030.046
Yeast
regulation of protein transportGO:00512231630.046
purine nucleoside metabolic processGO:00422782410.045
Yeast
ribonucleotide metabolic processGO:00092592910.042
Yeast
cellular protein complex assemblyGO:00436231160.042
Human
cellular amine metabolic processGO:0044106440.042
nucleoside triphosphate catabolic processGO:00091432050.042
Yeast
protein modification by small protein conjugationGO:00324461870.042
ribonucleotide catabolic processGO:00092612080.041
Yeast
positive regulation of cytoplasmic transportGO:1903651400.041
dna metabolic processGO:00062593030.040
response to growth factorGO:00708481980.040
positive regulation of proteolysisGO:0045862850.040
purine ribonucleoside metabolic processGO:00461282410.038
Yeast
germ cell developmentGO:00072811850.037
cellular protein catabolic processGO:00442571550.037
compound eye developmentGO:004874910.037
regulation of cellular component biogenesisGO:00440871810.037
regulation of proteolysisGO:00301621640.037
regulation of cell cycleGO:00517262810.036
nuclear exportGO:0051168340.036
purine containing compound metabolic processGO:00725213110.036
Yeast
mitotic cell cycle processGO:19030471590.035
regulation of protein localizationGO:00328802310.035
double strand break repairGO:0006302480.035
cellular response to cytokine stimulusGO:00713451890.035
membrane organizationGO:00610242450.035
Human
angiogenesisGO:00015252010.034
Rat
carbohydrate derivative biosynthetic processGO:19011371830.034
pole plasm assemblyGO:000731520.034
rhythmic processGO:00485111740.033
cellular component assembly involved in morphogenesisGO:00109271390.033
rna splicingGO:0008380540.033
muscle cell differentiationGO:00426922610.033
rna processingGO:00063961050.032
dephosphorylationGO:00163111290.032
regulation of cellular response to stressGO:00801351590.032
purine containing compound catabolic processGO:00725232130.032
Yeast
positive regulation of cell developmentGO:00107202370.031
positive regulation of protein transportGO:0051222930.031
response to organonitrogen compoundGO:00102432460.031
urogenital system developmentGO:00016552610.031
Rat
developmental maturationGO:00217001930.031
locomotory behaviorGO:00076261950.030
regulation of cell projection organizationGO:00313442060.030
rna splicing via transesterification reactionsGO:0000375430.030
nucleotide metabolic processGO:00091173320.030
Yeast
neuron apoptotic processGO:00514021420.030
cell type specific apoptotic processGO:00972852680.030
cellular response to dna damage stimulusGO:00069742070.030
nucleoside triphosphate metabolic processGO:00091412300.030
Yeast
negative regulation of protein metabolic processGO:00512482820.029
Rat
blood vessel morphogenesisGO:00485142850.029
Rat
regulation of cell motilityGO:20001452360.029
nuclear divisionGO:00002801580.029
maternal determination of anterior posterior axis embryoGO:000835820.029
regulation of cell migrationGO:00303342190.028
purine ribonucleoside catabolic processGO:00461302050.028
Yeast
organelle fissionGO:00482851700.028
positive regulation of hydrolase activityGO:00513451480.028
microtubule based processGO:00070172360.028
regulation of protein catabolic processGO:00421761080.028
nucleoside monophosphate catabolic processGO:0009125590.028
Yeast
synapse organizationGO:00508081250.027
ribonucleoprotein complex disassemblyGO:003298830.027
translationGO:0006412930.027
regulation of kinase activityGO:00435492490.027
development of primary sexual characteristicsGO:00451371430.027
Worm
response to oxidative stressGO:00069791230.027
regulation of intracellular protein transportGO:0033157820.027
regionalizationGO:00030023370.027
ribonucleoside monophosphate metabolic processGO:0009161800.026
Yeast
proteasomal protein catabolic processGO:0010498980.026
regulation of neuron projection developmentGO:00109751690.026
positive regulation of cellular component biogenesisGO:0044089940.026
body morphogenesisGO:0010171450.026
Worm
regulation of cytoplasmic transportGO:19036491120.026
cellular amino acid metabolic processGO:00065201030.025
regulation of neuron differentiationGO:00456642810.025
protein targetingGO:00066051430.025
Human
positive regulation of apoptotic processGO:00430652170.025
adult behaviorGO:00305341350.025
positive regulation of cell deathGO:00109422240.025
fertilizationGO:00095661270.025
cellular ketone metabolic processGO:0042180840.025
response to peptideGO:19016521360.025
regulation of cellular amine metabolic processGO:0033238200.024
establishment of protein localization to membraneGO:0090150540.024
Human
mitotic cell cycleGO:00002781950.024
negative regulation of molecular functionGO:00440922580.024
Rat
positive regulation of cellular catabolic processGO:00313311480.024
regulation of transferase activityGO:00513382630.024
positive regulation of cell projection organizationGO:0031346950.024
negative regulation of cell proliferationGO:00082852960.023
purine ribonucleoside triphosphate metabolic processGO:00092052200.023
Yeast
positive regulation of intracellular transportGO:0032388700.023
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.023
chemotaxisGO:00069352470.023
ribonucleoprotein complex subunit organizationGO:0071826280.023
regulation of cytoskeleton organizationGO:00514931220.023
cell maturationGO:00484691270.022
small gtpase mediated signal transductionGO:0007264970.022
muscle system processGO:00030121410.022
positive regulation of cell cycleGO:0045787920.022
microtubule cytoskeleton organizationGO:00002261570.022
ribonucleoprotein complex localizationGO:007116610.022
protein foldingGO:0006457280.022
Yeast
forebrain developmentGO:00309003020.021
positive regulation of cellular amino acid metabolic processGO:004576430.021
regulation of anatomical structure sizeGO:00900661780.021
positive regulation of cellular amine metabolic processGO:003324050.021
regulation of mitotic cell cycle phase transitionGO:1901990730.021
ribonucleoside monophosphate catabolic processGO:0009158570.021
Yeast
cell recognitionGO:0008037830.021
neuron deathGO:00709971540.021
nitrogen compound transportGO:00717052710.021
establishment of organelle localizationGO:00516561220.021
purine ribonucleotide catabolic processGO:00091542080.020
Yeast
actomyosin structure organizationGO:0031032560.020
negative regulation of cellular component organizationGO:00511291940.020
sperm egg recognitionGO:0035036370.020
pore complex assemblyGO:004693130.020
response to transforming growth factor betaGO:0071559880.020
inflammatory responseGO:00069542440.020
meiotic cell cycleGO:00513211220.020
chromatin organizationGO:00063252060.020
telencephalon developmentGO:00215371860.020
regulation of transpositionGO:001052820.019
stem cell differentiationGO:00488632680.019
rna localizationGO:0006403230.019
atp metabolic processGO:0046034750.019
Yeast
regulation of cellular amino acid metabolic processGO:000652150.019
dendrite developmentGO:00163581150.019
chromatin modificationGO:00165681870.019
single fertilizationGO:0007338820.019
pallium developmentGO:00215431200.019
transmembrane transportGO:00550854120.019
Human
organonitrogen compound biosynthetic processGO:19015661920.019
cellular protein complex disassemblyGO:0043624360.019
regulation of synaptic growth at neuromuscular junctionGO:000858240.019
lipid biosynthetic processGO:00086101790.018
receptor mediated endocytosisGO:0006898510.018
Worm
positive regulation of nucleocytoplasmic transportGO:0046824300.018
regulation of protein stabilityGO:0031647520.018
adult locomotory behaviorGO:0008344910.018
atp catabolic processGO:0006200550.018
Yeast
gene silencing by rnaGO:0031047190.018
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046610.018
cellular response to growth factor stimulusGO:00713631970.017
regulation of protein ubiquitinationGO:0031396520.017
immune effector processGO:00022523210.017
positive regulation of nervous system developmentGO:00519622210.017
maintenance of locationGO:0051235890.017
small molecule biosynthetic processGO:00442831320.017
fatty acid metabolic processGO:00066311210.017
protein targeting to mitochondrionGO:000662660.017
Human
anatomical structure homeostasisGO:00602491450.017
regulation of cellular ketone metabolic processGO:0010565660.016
negative regulation of phosphate metabolic processGO:00459361840.016
Rat
response to organic cyclic compoundGO:00140701980.016
muscle contractionGO:00069361010.016
mitochondrion organizationGO:00070051340.016
Human
response to radiationGO:00093141650.016
cation transportGO:00068123990.016
purine nucleoside monophosphate metabolic processGO:0009126810.016
Yeast
purine ribonucleoside monophosphate catabolic processGO:0009169570.016
Yeast
regulation of membrane potentialGO:00423911920.016
establishment or maintenance of cytoskeleton polarityGO:003095220.016
mrna processingGO:0006397630.016
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.015
positive regulation of intracellular protein transportGO:0090316420.015
learningGO:0007612980.015
single organismal cell cell adhesionGO:00163371310.015
nucleus organizationGO:0006997450.015
purine nucleoside monophosphate catabolic processGO:0009128580.015
Yeast
regulation of cell cycle processGO:00105641600.015
regulation of defense responseGO:00313472330.015
regulation of nucleocytoplasmic transportGO:0046822730.015
response to peptide hormoneGO:00434341270.015
circadian rhythmGO:00076231140.015
positive regulation of transferase activityGO:00513471670.015
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.015
positive regulation of protein localization to nucleusGO:1900182300.015
regulation of ion transportGO:00432692150.015
mrna splicing via spliceosomeGO:0000398430.015
response to extracellular stimulusGO:00099911270.015
response to light stimulusGO:00094161350.015
nucleoside monophosphate metabolic processGO:0009123850.014
Yeast
ossificationGO:00015032160.014
maturation of 5 8s rrnaGO:000046010.014
cellular response to organonitrogen compoundGO:00714171450.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.014
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.014
regulation of protein modification by small protein conjugation or removalGO:1903320570.014
response to insulinGO:00328681000.014
regulation of cell cycle phase transitionGO:1901987770.014
regulation of muscle system processGO:0090257800.014
circulatory system processGO:00030131970.014
positive regulation of mrna metabolic processGO:1903313170.014
regulation of response to woundingGO:19030341890.014
blood circulationGO:00080151950.014
multicellular organismal homeostasisGO:00488711640.014
mitotic cell cycle checkpointGO:0007093310.014
regulation of neuron apoptotic processGO:00435231220.014
regulation of cellular component sizeGO:00325351210.014
regulation of multi organism processGO:00439001110.014
skeletal muscle organ developmentGO:00605381630.014
nucleoside phosphate biosynthetic processGO:1901293790.014
posttranscriptional gene silencingGO:0016441100.014
ras protein signal transductionGO:0007265770.014
meiotic cell cycle processGO:1903046770.014
response to temperature stimulusGO:0009266550.014
Rat
sensory perceptionGO:00076002450.014
cellular lipid metabolic processGO:00442553230.014
neuron migrationGO:00017641220.014
purine ribonucleoside monophosphate metabolic processGO:0009167800.014
Yeast
mitotic cytokinesisGO:000028140.014
innate immune responseGO:00450871570.014
regulation of chromosome organizationGO:0033044830.014
lipid localizationGO:00108761260.013
regulation of mitotic cell cycleGO:00073461260.013
cajal body organizationGO:003057610.013
mitochondrial translationGO:003254340.013
organophosphate biosynthetic processGO:00904071220.013
cell cell recognitionGO:0009988440.013
positive regulation of organelle organizationGO:00106381280.013
negative regulation of transferase activityGO:0051348850.013
organelle localizationGO:00516401790.013
epithelial tube morphogenesisGO:00605623030.013
regulation of hydrolase activityGO:00513362460.013
proteasome assemblyGO:004324810.013
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112330.013
regulation of endopeptidase activityGO:0052548890.013
cytokine productionGO:00018163190.013
regulation of protein serine threonine kinase activityGO:00719001570.013
lateral inhibitionGO:004633110.013
posttranscriptional gene silencing by rnaGO:0035194100.012
lipid transportGO:0006869980.012
negative regulation of cell developmentGO:00107211690.012
stem cell developmentGO:00488642190.012
negative regulation of transpositionGO:001052920.012
regulation of circadian rhythmGO:0042752580.012
regulation of translationGO:0006417710.012
regulation of homeostatic processGO:00328441820.012
cation transmembrane transportGO:00986552660.012
mapk cascadeGO:00001652810.012
gland developmentGO:00487323300.012
regulation of cell adhesionGO:00301551540.012
stress granule disassemblyGO:003561720.012
regulation of protein complex assemblyGO:0043254830.012
positive regulation of cell migrationGO:00303351090.012
regulation of peptidase activityGO:0052547960.012
muscle cell developmentGO:00550011330.012
spermatid differentiationGO:00485151150.012
establishment or maintenance of cell polarityGO:0007163860.012
positive regulation of programmed cell deathGO:00430682180.012
protein modification by small protein removalGO:0070646210.012
stress activated mapk cascadeGO:0051403800.012
negative regulation of cell cycleGO:00457861230.012
positive regulation of protein modification processGO:00314012990.011
negative regulation of immune system processGO:00026832090.011
cognitionGO:00508901490.011
renal system developmentGO:00720012250.011
Rat
oocyte differentiationGO:0009994350.011
regulation of protein targetingGO:1903533610.011
endomembrane system organizationGO:00102561470.011
intrinsic apoptotic signaling pathwayGO:00971931320.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.011
regulation of metal ion transportGO:00109591060.011
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.011
developmental growth involved in morphogenesisGO:00605601380.011
asymmetric stem cell divisionGO:009872230.011
positive regulation of protein phosphorylationGO:00019342420.011
negative regulation of neuron apoptotic processGO:0043524920.011
positive regulation of chromosome organizationGO:2001252330.011
transmission of nerve impulseGO:0019226760.011
positive regulation of cell motilityGO:20001471160.011
regulation of cytokine productionGO:00018172660.011
gtp metabolic processGO:00460391440.011
ncrna processingGO:0034470260.011
positive regulation of peptidase activityGO:0010952490.011
regulation of stress activated mapk cascadeGO:0032872690.011
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.011
positive regulation of homeostatic processGO:0032846640.011
positive regulation of growthGO:00459271040.010
molting cycleGO:0042303900.010
digestive tract morphogenesisGO:00485461470.010
binding of sperm to zona pellucidaGO:0007339340.010
cellular response to hormone stimulusGO:00328701500.010
synaptic transmissionGO:00072683290.010
regulation of hormone levelsGO:00108172110.010
regulation of protein kinase activityGO:00458592320.010
regulation of proteasomal protein catabolic processGO:0061136460.010
positive regulation of kinase activityGO:00336741550.010
regulation of protein localization to nucleusGO:1900180600.010
spindle organizationGO:0007051280.010

Hspa4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012
organ system cancerDOID:005068600.012
hematologic cancerDOID:253100.010
immune system cancerDOID:006008300.010