Mus musculus

24 known processes

Hspa9

heat shock protein 9

(Aliases: 74kDa,Hsc74,Mortalin,Mot-2,Hspa9a,Csa,Mthsp70,Hsp74a,Mot2,Grp75,Hsp74,Pbp74)

Hspa9 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein targeting to mitochondrionGO:000662660.926
Yeast
mitochondrion organizationGO:00070051340.845
Yeast Fly
protein localization to mitochondrionGO:0070585150.830
Yeast
positive regulation of immune response to tumor cellGO:000283960.794
response to endoplasmic reticulum stressGO:0034976530.706
translationGO:0006412930.548
regulation of t cell activationGO:00508631700.547
positive regulation of macrophage activationGO:0043032100.477
dna metabolic processGO:00062593030.463
Yeast
positive regulation of interferon alpha productionGO:003272740.402
nucleobase containing small molecule metabolic processGO:00550863520.387
Yeast
mitochondrial translationGO:003254340.366
regulation of macrophage activationGO:0043030170.363
somatic cell dna recombinationGO:0016444510.346
positive regulation of t cell activationGO:00508701010.316
protein refoldingGO:004202610.306
Yeast
protein importGO:00170381010.302
Yeast
purine ribonucleoside triphosphate metabolic processGO:00092052200.279
Yeast
purine ribonucleoside metabolic processGO:00461282410.274
Yeast
purine ribonucleotide metabolic processGO:00091502900.273
Yeast
regulation of response to tumor cellGO:000283460.260
cell agingGO:0007569350.237
endoplasmic reticulum unfolded protein responseGO:0030968190.230
establishment of protein localization to organelleGO:00725941180.229
Yeast
regulation of lymphocyte activationGO:00512492400.219
protein targetingGO:00066051430.217
Yeast
cristae formationGO:004240730.213
regulation of lymphocyte mediated immunityGO:0002706840.213
regulation of cell activationGO:00508652890.203
purine nucleoside metabolic processGO:00422782410.188
Yeast
lymphocyte mediated immunityGO:00024491390.184
lymphocyte proliferationGO:00466511640.181
t cell activationGO:00421102890.181
protein foldingGO:0006457280.178
Yeast
positive regulation of cell activationGO:00508671580.178
coenzyme metabolic processGO:0006732520.170
positive regulation of lymphocyte activationGO:00512511400.169
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.167
membrane organizationGO:00610242450.166
transmembrane transportGO:00550854120.164
Yeast
ribose phosphate metabolic processGO:00196932910.161
Yeast
protein processingGO:00164851630.159
glycosyl compound metabolic processGO:19016572460.158
Yeast
response to topologically incorrect proteinGO:0035966250.154
mitochondrial membrane organizationGO:0007006260.153
atp metabolic processGO:0046034750.145
Yeast
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.145
organophosphate catabolic processGO:00464342320.141
Yeast
positive regulation of cytokine productionGO:00018191740.138
cellular protein complex assemblyGO:00436231160.137
regulation of response to biotic stimulusGO:0002831380.136
purine containing compound metabolic processGO:00725213110.134
Yeast
aromatic compound catabolic processGO:00194392860.132
Yeast
cellular response to topologically incorrect proteinGO:0035967250.131
wound healingGO:00420601570.130
Zebrafish
ribonucleoside triphosphate catabolic processGO:00092031990.129
Yeast
lymphocyte activation involved in immune responseGO:0002285930.127
er nucleus signaling pathwayGO:0006984270.125
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.125
cell type specific apoptotic processGO:00972852680.124
protein localization to membraneGO:00726571080.123
generation of precursor metabolites and energyGO:00060911030.122
myeloid leukocyte activationGO:0002274830.115
regulation of interferon gamma productionGO:0032649570.115
tissue regenerationGO:0042246220.112
Zebrafish
mitochondrial transportGO:0006839360.110
Yeast
ribonucleoside triphosphate metabolic processGO:00091992200.109
Yeast
purine nucleoside triphosphate metabolic processGO:00091442260.108
Yeast
nucleoside phosphate metabolic processGO:00067533380.107
Yeast
purine nucleoside monophosphate metabolic processGO:0009126810.106
Yeast
positive regulation of interferon gamma productionGO:0032729390.105
protein maturationGO:00516041760.104
type i interferon productionGO:0032606290.104
carbohydrate derivative catabolic processGO:19011362310.104
Yeast
cytokine production involved in immune responseGO:0002367340.103
reactive nitrogen species metabolic processGO:200105700.101
positive regulation of innate immune responseGO:0045089800.100
positive regulation of cysteine type endopeptidase activityGO:2001056390.099
cytoplasmic transportGO:00164822340.098
cellular amino acid metabolic processGO:00065201030.097
regulation of type i interferon productionGO:0032479220.096
male gamete generationGO:00482322850.095
dna replicationGO:0006260520.094
purine nucleoside catabolic processGO:00061522050.094
Yeast
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.094
nucleotide catabolic processGO:00091662170.093
Yeast
intracellular protein transportGO:00068862040.093
innate immune responseGO:00450871570.092
regulation of translationGO:0006417710.091
ribonucleoside catabolic processGO:00424542060.090
Yeast
regulation of innate immune responseGO:0045088910.089
regulation of defense responseGO:00313472330.087
regulation of mitochondrion organizationGO:0010821270.087
regulation of organelle organizationGO:00330432890.086
nucleotide metabolic processGO:00091173320.085
Yeast
toll like receptor signaling pathwayGO:0002224380.085
purine nucleotide catabolic processGO:00061952110.085
Yeast
glycosyl compound catabolic processGO:19016582060.084
Yeast
nucleoside triphosphate metabolic processGO:00091412300.083
Yeast
positive regulation of peptidase activityGO:0010952490.083
regulation of immune response to tumor cellGO:000283760.081
cellular nitrogen compound catabolic processGO:00442702800.081
Yeast
positive regulation of response to tumor cellGO:000283660.078
heterocycle catabolic processGO:00467002800.078
Yeast
cytokine productionGO:00018163190.078
nonmotile primary cilium assemblyGO:003505880.078
response to oxidative stressGO:00069791230.077
negative regulation of protein metabolic processGO:00512482820.075
regulation of interleukin 6 productionGO:0032675550.075
nucleoside metabolic processGO:00091162460.074
Yeast
ribonucleoside metabolic processGO:00091192450.074
Yeast
regulation of mitochondrial translationGO:007012930.073
activation of cysteine type endopeptidase activityGO:0097202270.073
leukocyte proliferationGO:00706611720.072
ribonucleotide catabolic processGO:00092612080.072
Yeast
posttranscriptional regulation of gene expressionGO:00106081550.070
organic cyclic compound catabolic processGO:19013612950.070
Yeast
sulfur compound metabolic processGO:00067901000.070
regulation of mitochondrial fissionGO:009014030.068
neuron apoptotic processGO:00514021420.067
renal system developmentGO:00720012250.067
b cell activation involved in immune responseGO:0002312500.067
urogenital system developmentGO:00016552610.066
trna aminoacylationGO:004303910.066
nucleoside catabolic processGO:00091642060.064
Yeast
purine containing compound catabolic processGO:00725232130.064
Yeast
positive regulation of type i interferon productionGO:0032481140.064
leukocyte mediated immunityGO:00024431740.064
spermatogenesisGO:00072832840.063
positive regulation of hydrolase activityGO:00513451480.063
Yeast
epithelial tube morphogenesisGO:00605623030.062
zymogen activationGO:0031638410.061
organic acid biosynthetic processGO:0016053860.060
ribonucleoside monophosphate catabolic processGO:0009158570.060
Yeast
ribonucleotide metabolic processGO:00092592910.059
Yeast
purine nucleoside triphosphate catabolic processGO:00091462030.058
Yeast
nucleoside triphosphate catabolic processGO:00091432050.058
Yeast
dna recombinationGO:0006310920.058
positive regulation of interleukin 6 productionGO:0032755370.057
response to tumor cellGO:000234780.057
regulation of t cell proliferationGO:0042129920.057
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.057
establishment of protein localization to mitochondrionGO:0072655110.057
Yeast
purine nucleotide metabolic processGO:00061633020.056
Yeast
positive regulation of cell deathGO:00109422240.056
regenerationGO:0031099380.054
Zebrafish
trna aminoacylation for protein translationGO:000641810.054
macrophage activationGO:0042116270.053
interleukin 6 productionGO:0032635580.052
immune effector processGO:00022523210.051
negative regulation of cell proliferationGO:00082852960.051
regulation of cysteine type endopeptidase activityGO:2000116650.051
activation induced cell death of t cellsGO:0006924100.050
ribonucleoside monophosphate metabolic processGO:0009161800.050
Yeast
activation of immune responseGO:00022531380.050
purine ribonucleotide catabolic processGO:00091542080.049
Yeast
immune response activating signal transductionGO:00027571160.049
activation of innate immune responseGO:0002218560.049
de novo protein foldingGO:000645890.049
somatic diversification of immune receptorsGO:0002200530.048
cellular lipid metabolic processGO:00442553230.048
pattern recognition receptor signaling pathwayGO:0002221470.048
innate immune response activating signal transductionGO:0002758500.047
cofactor biosynthetic processGO:0051188410.046
regulation of t cell mediated immunityGO:0002709340.045
nucleoside phosphate catabolic processGO:19012922220.045
Yeast
organonitrogen compound catabolic processGO:19015652640.045
Yeast
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.045
somatic recombination of immunoglobulin gene segmentsGO:0016447420.044
regulation of endopeptidase activityGO:0052548890.044
b cell activationGO:00421131610.044
positive regulation of defense responseGO:00313491240.044
kidney developmentGO:00018222130.043
nucleoside monophosphate metabolic processGO:0009123850.043
Yeast
positive regulation of leukocyte mediated immunityGO:0002705700.043
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.043
neuron deathGO:00709971540.043
sperm egg recognitionGO:0035036370.042
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.042
immunoglobulin productionGO:0002377730.042
b cell proliferationGO:0042100530.042
leukocyte activation involved in immune responseGO:00023661260.042
atp catabolic processGO:0006200550.042
Yeast
cellular response to oxidative stressGO:0034599760.042
regulation of leukocyte mediated immunityGO:00027031040.042
interleukin 12 productionGO:0032615320.042
positive regulation of adaptive immune responseGO:0002821610.042
organelle fusionGO:0048284280.041
sulfur compound biosynthetic processGO:0044272370.041
response to unfolded proteinGO:0006986210.041
positive regulation of leukocyte proliferationGO:0070665730.041
regulation of adaptive immune responseGO:0002819900.040
retina homeostasisGO:0001895230.040
response to hypoxiaGO:0001666580.040
immune response regulating signaling pathwayGO:00027641250.040
postsynaptic membrane organizationGO:0001941180.040
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.040
small molecule biosynthetic processGO:00442831320.039
protein stabilizationGO:0050821250.038
positive regulation of immune effector processGO:00026991070.038
mitochondrial fusionGO:000805390.038
coenzyme biosynthetic processGO:0009108230.038
b cell mediated immunityGO:0019724710.038
cellular amide metabolic processGO:0043603580.038
somatic diversification of immunoglobulinsGO:0016445430.038
regulation of hydrolase activityGO:00513362460.038
Yeast
myd88 dependent toll like receptor signaling pathwayGO:000275570.037
positive regulation of interleukin 12 productionGO:0032735210.037
production of molecular mediator of immune responseGO:00024401030.037
lateral inhibitionGO:004633110.036
response to heatGO:0009408270.036
cellular modified amino acid metabolic processGO:0006575630.036
immunoglobulin mediated immune responseGO:0016064690.036
response to temperature stimulusGO:0009266550.035
oxidation reduction processGO:00551143420.035
protein methylationGO:0006479810.035
inner mitochondrial membrane organizationGO:000700750.034
intrinsic apoptotic signaling pathwayGO:00971931320.034
positive regulation of t cell proliferationGO:0042102520.034
multicellular organismal agingGO:0010259240.033
nucleoside monophosphate catabolic processGO:0009125590.032
Yeast
t cell proliferationGO:00420981200.032
t cell mediated immunityGO:0002456500.032
regulation of interleukin 12 productionGO:0032655300.032
regulation of reactive oxygen species biosynthetic processGO:190342620.032
cell activation involved in immune responseGO:00022631260.032
gas homeostasisGO:003348330.032
regulation of reactive oxygen species metabolic processGO:2000377400.031
positive regulation of lymphocyte mediated immunityGO:0002708620.031
protein localization to organelleGO:00333651850.031
Yeast
purine ribonucleoside monophosphate metabolic processGO:0009167800.031
Yeast
purine ribonucleoside catabolic processGO:00461302050.031
Yeast
reactive oxygen species metabolic processGO:0072593840.031
positive regulation of t cell mediated immunityGO:0002711240.029
locomotory behaviorGO:00076261950.029
fatty acid biosynthetic processGO:0006633410.029
negative regulation of apoptotic signaling pathwayGO:20012341040.028
regulation of interleukin 10 productionGO:0032653210.028
alpha amino acid metabolic processGO:1901605590.028
regulation of peptidase activityGO:0052547960.028
binding of sperm to zona pellucidaGO:0007339340.028
ensheathment of neuronsGO:0007272760.028
positive regulation of endopeptidase activityGO:0010950430.027
homeostasis of number of cellsGO:00488722100.027
digestive tract morphogenesisGO:00485461470.027
inflammatory responseGO:00069542440.027
purine nucleoside monophosphate catabolic processGO:0009128580.027
Yeast
small gtpase mediated signal transductionGO:0007264970.026
positive regulation of reactive oxygen species biosynthetic processGO:190342820.026
regulation of proteolysisGO:00301621640.025
mitochondrial dna metabolic processGO:0032042130.025
positive regulation of lymphocyte proliferationGO:0050671700.025
heart morphogenesisGO:00030071780.025
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.025
adaptive immune responseGO:00022501550.025
camera type eye developmentGO:00430102660.024
organelle assemblyGO:00709251770.024
response to inorganic substanceGO:0010035960.024
mitochondrial dna replicationGO:000626470.024
regulation of kinase activityGO:00435492490.024
epithelial cell proliferationGO:00506731740.024
action potentialGO:0001508780.023
negative regulation of response to oxidative stressGO:1902883100.023
regulation of phosphatidylcholine biosynthetic processGO:200124520.023
regulation of membrane potentialGO:00423911920.023
Fly
multicellular organism growthGO:00352641610.022
response to organonitrogen compoundGO:00102432460.022
transmission of nerve impulseGO:0019226760.022
neuronal action potentialGO:0019228540.022
purine ribonucleoside triphosphate catabolic processGO:00092071990.021
Yeast
leukocyte apoptotic processGO:0071887710.021
morphogenesis of embryonic epitheliumGO:00163311590.021
carboxylic acid biosynthetic processGO:0046394860.021
spermatid differentiationGO:00485151150.021
lymphocyte apoptotic processGO:0070227540.021
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.021
lymphocyte homeostasisGO:0002260640.020
gtp catabolic processGO:00061841430.020
acetyl coa biosynthetic processGO:000608550.020
photoreceptor cell developmentGO:0042461400.020
phosphatidylethanolamine metabolic processGO:004633720.020
cell adhesionGO:00071553290.020
cellular respirationGO:0045333380.020
embryonic epithelial tube formationGO:00018381300.020
response to organic cyclic compoundGO:00140701980.020
positive regulation of apoptotic processGO:00430652170.020
purine ribonucleoside monophosphate catabolic processGO:0009169570.019
Yeast
single organismal cell cell adhesionGO:00163371310.019
oxidoreduction coenzyme metabolic processGO:0006733160.019
protein catabolic processGO:00301632210.019
monocarboxylic acid biosynthetic processGO:0072330610.019
actin cytoskeleton organizationGO:00300362200.019
selenium compound metabolic processGO:000188730.019
t cell differentiation in thymusGO:0033077770.019
reactive oxygen species biosynthetic processGO:190340980.019
positive regulation of proteolysisGO:0045862850.019
response to reactive oxygen speciesGO:0000302560.018
digestive system developmentGO:00551232000.018
synapse organizationGO:00508081250.018
negative regulation of cellular component organizationGO:00511291940.018
multicellular organismal homeostasisGO:00488711640.018
peptide metabolic processGO:0006518460.018
endocytosisGO:00068971680.018
angiogenesisGO:00015252010.018
regulation of lymphocyte proliferationGO:00506701170.018
serine family amino acid metabolic processGO:000906970.017
positive regulation of interleukin 10 productionGO:0032733120.017
interleukin 10 productionGO:0032613230.017
positive regulation of transcription from rna polymerase i promoterGO:004594330.017
negative regulation of intracellular signal transductionGO:19025321670.017
single organism cell adhesionGO:00986021560.017
adult behaviorGO:00305341350.017
inorganic cation transmembrane transportGO:00986622070.017
organelle localizationGO:00516401790.017
determination of adult lifespanGO:0008340110.016
apoptotic signaling pathwayGO:00971903060.016
single fertilizationGO:0007338820.016
multicellular organismal signalingGO:0035637910.016
leukocyte homeostasisGO:0001776790.016
energy derivation by oxidation of organic compoundsGO:0015980770.016
response to increased oxygen levelsGO:003629620.016
axonogenesisGO:00074092740.016
cofactor metabolic processGO:0051186800.016
cell cell recognitionGO:0009988440.016
cell fate commitmentGO:00451652100.016
regulation of leukocyte proliferationGO:00706631210.015
regulation of establishment of protein localizationGO:00702011810.015
gtp metabolic processGO:00460391440.015
regulation of protein targetingGO:1903533610.015
positive regulation of reactive oxygen species metabolic processGO:2000379110.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.015
amine metabolic processGO:0009308450.015
regulation of anatomical structure sizeGO:00900661780.015
positive regulation of programmed cell deathGO:00430682180.015
negative regulation of neuron apoptotic processGO:0043524920.015
gonad developmentGO:00084061410.014
t cell apoptotic processGO:0070231390.014
cellular response to inorganic substanceGO:0071241370.014
age dependent response to oxidative stressGO:000130630.014
establishment of protein localization to endoplasmic reticulumGO:007259920.014
response to oxygen levelsGO:0070482620.014
regulation of neuron apoptotic processGO:00435231220.014
regulation of cell adhesionGO:00301551540.014
ion transmembrane transportGO:00342203610.014
ossificationGO:00015032160.014
mesenchymal cell developmentGO:0014031930.014
neural tube formationGO:00018411080.014
male sex differentiationGO:00466611090.014
fertilizationGO:00095661270.014
regulation of protein transportGO:00512231630.014
response to growth factorGO:00708481980.014
cilium morphogenesisGO:00602711020.014
positive regulation of cellular amine metabolic processGO:003324050.013
regulation of protein bindingGO:0043393600.013
photoreceptor cell differentiationGO:0046530520.013
amino acid activationGO:004303810.013
regulation of interferon alpha productionGO:003264750.013
regulation of protein serine threonine kinase activityGO:00719001570.013
nuclear importGO:0051170950.013
protein transmembrane transportGO:007180680.013
Yeast
nitrogen compound transportGO:00717052710.013
t cell differentiationGO:00302171740.013
trna metabolic processGO:0006399110.013
positive regulation of transferase activityGO:00513471670.013
cofactor transportGO:005118140.013
regulation of cellular component biogenesisGO:00440871810.013
sperm motilityGO:0030317470.013
protein oligomerizationGO:0051259670.012
response to metal ionGO:0010038470.012
mitochondrial genome maintenanceGO:0000002150.012
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919270.012
interferon alpha productionGO:003260770.012
fat cell differentiationGO:00454441600.012
intermediate filament cytoskeleton organizationGO:0045104260.012
organonitrogen compound biosynthetic processGO:19015661920.012
acetyl coa biosynthetic process from pyruvateGO:000608630.012
response to acid chemicalGO:00011011110.012
cell recognitionGO:0008037830.012
myelinationGO:0042552740.012
striated muscle myosin thick filament assemblyGO:007168810.012
regulation of hormone levelsGO:00108172110.012
cation transmembrane transportGO:00986552660.012
regulation of protein localizationGO:00328802310.012
defecationGO:003042110.012
oxygen homeostasisGO:003236420.011
germ cell developmentGO:00072811850.011
negative regulation of cellular protein metabolic processGO:00322692470.011
positive regulation of striated muscle contractionGO:004598930.011
negative regulation of dna replicationGO:000815640.011
cellular amine metabolic processGO:0044106440.011
regulation of secretion by cellGO:19035302490.011
cellular response to growth factor stimulusGO:00713631970.011
lipid biosynthetic processGO:00086101790.011
toxin transportGO:1901998380.011
blood vessel morphogenesisGO:00485142850.011
pole plasm assemblyGO:000731520.011
negative regulation of molecular functionGO:00440922580.011
oxidative phosphorylationGO:0006119140.011
regulation of cell motilityGO:20001452360.011
membrane fusionGO:0061025380.011
cellular response to organonitrogen compoundGO:00714171450.011
dicarboxylic acid metabolic processGO:0043648180.011
glutathione metabolic processGO:0006749160.011
leukocyte differentiationGO:00025213420.011
regulation of transmembrane transportGO:00347621280.011
circulatory system processGO:00030131970.011
mesenchymal cell differentiationGO:00487621070.011
blood circulationGO:00080151950.011
mitochondrial protein processingGO:003498250.011
negative regulation of alcohol biosynthetic processGO:190293140.010
hemostasisGO:0007599780.010
regulation of protein localization to nucleusGO:1900180600.010
rhythmic processGO:00485111740.010
folic acid containing compound metabolic processGO:000676030.010
maternal determination of anterior posterior axis embryoGO:000835820.010
pyridine nucleotide biosynthetic processGO:001936340.010
fatty acid metabolic processGO:00066311210.010
response to decreased oxygen levelsGO:0036293590.010
regulation of cellular response to stressGO:00801351590.010
regulation of epithelial cell proliferationGO:00506781410.010
cellular response to oxygen radicalGO:0071450140.010
intermediate filament organizationGO:0045109150.010
negative regulation of epithelial cell proliferationGO:0050680640.010
lymphocyte differentiationGO:00300982420.010

Hspa9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.498
disease of anatomical entityDOID:700.498
paraplegiaDOID:60700.270
hereditary spastic paraplegiaDOID:247600.270
central nervous system diseaseDOID:33100.270
muscular diseaseDOID:008000000.035
musculoskeletal system diseaseDOID:1700.035
myopathyDOID:42300.031
muscle tissue diseaseDOID:6600.031
neurodegenerative diseaseDOID:128900.031
neuromuscular diseaseDOID:44000.016
neuropathyDOID:87000.016
nephronophthisisDOID:1271200.015
joubert syndromeDOID:005077700.015
charcot marie tooth diseaseDOID:1059500.013
muscular dystrophyDOID:988400.010