Mus musculus

102 known processes

Opa1

optic atrophy 1 homolog (human)

(Aliases: mKIAA0567,AI847218,AI225888,1200011N24Rik,lilr3)

Opa1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mitochondrion organizationGO:00070051340.549
membrane organizationGO:00610242450.327
coenzyme metabolic processGO:0006732520.162
regulation of organelle organizationGO:00330432890.140
macromolecule catabolic processGO:00090572810.127
Worm
cellular amino acid metabolic processGO:00065201030.111
heterocycle catabolic processGO:00467002800.106
cytoplasmic transportGO:00164822340.105
mitochondrial translationGO:003254340.100
cation transportGO:00068123990.097
cellular homeostasisGO:00197252400.087
synapse organizationGO:00508081250.086
intrinsic apoptotic signaling pathwayGO:00971931320.081
cofactor metabolic processGO:0051186800.081
nucleobase containing small molecule metabolic processGO:00550863520.079
regulation of protein transportGO:00512231630.078
cellular ion homeostasisGO:00068731650.075
mitochondrial fusionGO:000805390.075
organic cyclic compound catabolic processGO:19013612950.074
positive regulation of nfat protein import into nucleusGO:005153310.072
coenzyme biosynthetic processGO:0009108230.068
nuclear transportGO:00511691390.067
organelle fusionGO:0048284280.067
purine ribonucleoside metabolic processGO:00461282410.067
cellular chemical homeostasisGO:00550822150.067
chromatin organizationGO:00063252060.067
protein catabolic processGO:00301632210.066
Worm
establishment of protein localization to organelleGO:00725941180.066
ion transmembrane transportGO:00342203610.065
negative regulation of immune system processGO:00026832090.063
protein processingGO:00164851630.062
cation homeostasisGO:00550802120.062
neuron migrationGO:00017641220.062
cellular ketone metabolic processGO:0042180840.061
regulation of cellular amino acid metabolic processGO:000652150.060
regulation of protein localizationGO:00328802310.060
regulation of establishment of protein localizationGO:00702011810.060
proteolysis involved in cellular protein catabolic processGO:00516031470.059
cellular amine metabolic processGO:0044106440.059
intracellular protein transportGO:00068862040.058
transmembrane transportGO:00550854120.056
regulation of release of cytochrome c from mitochondriaGO:0090199110.056
regulation of cellular ketone metabolic processGO:0010565660.053
mitotic cell cycleGO:00002781950.053
protein localization to organelleGO:00333651850.052
positive regulation of cellular amino acid metabolic processGO:004576430.052
protein maturationGO:00516041760.052
oxidation reduction processGO:00551143420.051
cofactor biosynthetic processGO:0051188410.051
regulation of mitochondrial fissionGO:009014030.050
negative regulation of intracellular signal transductionGO:19025321670.048
dna metabolic processGO:00062593030.047
membrane fusionGO:0061025380.047
organonitrogen compound catabolic processGO:19015652640.047
nucleoside metabolic processGO:00091162460.046
multicellular organismal homeostasisGO:00488711640.046
cellular metal ion homeostasisGO:00068751510.046
monocarboxylic acid metabolic processGO:00327871910.046
protein targetingGO:00066051430.046
amine metabolic processGO:0009308450.044
anatomical structure homeostasisGO:00602491450.044
purine ribonucleotide metabolic processGO:00091502900.043
action potentialGO:0001508780.043
regulation of defense responseGO:00313472330.043
regulation of intracellular transportGO:00323861590.043
release of cytochrome c from mitochondriaGO:0001836230.042
cellular macromolecule catabolic processGO:00442652060.042
translationGO:0006412930.042
positive regulation of cellular amine metabolic processGO:003324050.041
regulation of protein targetingGO:1903533610.041
regulation of secretion by cellGO:19035302490.040
divalent metal ion transportGO:00708381720.040
leukocyte differentiationGO:00025213420.039
regulation of intracellular protein transportGO:0033157820.038
transmission of nerve impulseGO:0019226760.038
protein importGO:00170381010.038
ras protein signal transductionGO:0007265770.037
regulation of synaptic growth at neuromuscular junctionGO:000858240.037
positive regulation of organelle organizationGO:00106381280.037
regulation of cell cycleGO:00517262810.036
purine nucleoside metabolic processGO:00422782410.036
regulation of cytoplasmic transportGO:19036491120.035
response to growth factorGO:00708481980.035
ribose phosphate metabolic processGO:00196932910.035
regulation of homeostatic processGO:00328441820.035
mitotic cell cycle processGO:19030471590.035
regulation of cellular amine metabolic processGO:0033238200.035
t cell activationGO:00421102890.035
regulation of nucleocytoplasmic transportGO:0046822730.035
maintenance of locationGO:0051235890.035
nucleotide metabolic processGO:00091173320.035
forebrain developmentGO:00309003020.034
homeostasis of number of cellsGO:00488722100.034
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.034
nucleoside phosphate catabolic processGO:19012922220.034
glycosyl compound metabolic processGO:19016572460.034
digestive system developmentGO:00551232000.033
nucleoside phosphate metabolic processGO:00067533380.033
ribonucleotide metabolic processGO:00092592910.033
small gtpase mediated signal transductionGO:0007264970.033
chromatin modificationGO:00165681870.033
divalent inorganic cation homeostasisGO:00725071380.033
aromatic compound catabolic processGO:00194392860.033
regulation of membrane potentialGO:00423911920.032
divalent inorganic cation transportGO:00725111780.032
organonitrogen compound biosynthetic processGO:19015661920.031
histone modificationGO:00165701590.031
cellular nitrogen compound catabolic processGO:00442702800.031
purine containing compound catabolic processGO:00725232130.031
calcium ion homeostasisGO:00550741270.030
modification dependent protein catabolic processGO:00199411330.030
digestive tract developmentGO:00485651900.030
metal ion homeostasisGO:00550651890.030
response to reactive oxygen speciesGO:0000302560.030
Worm
engulfment of apoptotic cellGO:004365230.030
covalent chromatin modificationGO:00165691630.030
cellular calcium ion homeostasisGO:00068741190.029
protein modification by small protein conjugation or removalGO:00706472070.029
peptidyl amino acid modificationGO:00181933360.029
apoptotic mitochondrial changesGO:0008637480.029
regulation of cellular catabolic processGO:00313292420.028
metencephalon developmentGO:0022037890.028
lipid biosynthetic processGO:00086101790.028
organic anion transportGO:00157111370.028
nucleocytoplasmic transportGO:00069131390.028
myeloid leukocyte differentiationGO:00025731190.028
carbohydrate metabolic processGO:00059752300.028
multi multicellular organism processGO:00447061090.028
cellular divalent inorganic cation homeostasisGO:00725031270.028
nitrogen compound transportGO:00717052710.028
telencephalon developmentGO:00215371860.027
response to organonitrogen compoundGO:00102432460.027
epithelial cell proliferationGO:00506731740.027
regulation of apoptotic signaling pathwayGO:20012331970.027
muscle cell developmentGO:00550011330.027
ribonucleoside triphosphate metabolic processGO:00091992200.027
organelle localizationGO:00516401790.027
muscle tissue developmentGO:00605373080.027
regulation of lymphocyte activationGO:00512492400.026
lymphocyte differentiationGO:00300982420.026
cellular response to cytokine stimulusGO:00713451890.026
calcium ion transportGO:00068161590.026
inorganic cation transmembrane transportGO:00986622070.026
blood vessel morphogenesisGO:00485142850.026
regulation of ion transmembrane transportGO:00347651190.025
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.025
cellular protein catabolic processGO:00442571550.025
regulation of ion transportGO:00432692150.025
muscle cell differentiationGO:00426922610.024
neuronal action potentialGO:0019228540.024
mitochondrion distributionGO:004831140.024
lymphocyte proliferationGO:00466511640.024
single organism nuclear importGO:1902593950.024
response to oxidative stressGO:00069791230.024
Worm
positive regulation of intracellular transportGO:0032388700.024
ribonucleoside metabolic processGO:00091192450.024
cellular response to growth factor stimulusGO:00713631970.024
organophosphate catabolic processGO:00464342320.024
cytokine productionGO:00018163190.023
striated muscle tissue developmentGO:00147062930.023
t cell proliferationGO:00420981200.023
digestive tract morphogenesisGO:00485461470.022
anion transportGO:00068201770.022
positive regulation of protein modification processGO:00314012990.022
ribonucleotide catabolic processGO:00092612080.022
protein modification by small protein conjugationGO:00324461870.022
lymphocyte homeostasisGO:0002260640.022
lipid localizationGO:00108761260.022
defense response to other organismGO:00985421970.021
negative regulation of cell proliferationGO:00082852960.021
protein secretionGO:00093061110.021
ossificationGO:00015032160.021
endocytosisGO:00068971680.021
regulation of protein localization to nucleusGO:1900180600.021
protein oligomerizationGO:0051259670.021
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.021
multicellular organism growthGO:00352641610.021
Worm
cellular lipid metabolic processGO:00442553230.021
skeletal system developmentGO:00015013560.021
inorganic ion transmembrane transportGO:00986602340.020
myeloid cell differentiationGO:00300992330.020
meiotic cell cycle processGO:1903046770.020
hindbrain developmentGO:00309021280.020
heart morphogenesisGO:00030071780.020
regulation of anatomical structure sizeGO:00900661780.020
cell type specific apoptotic processGO:00972852680.019
regulation of mitochondrion organizationGO:0010821270.019
positive regulation of nucleocytoplasmic transportGO:0046824300.019
leukocyte homeostasisGO:0001776790.019
purine nucleotide metabolic processGO:00061633020.019
positive regulation of protein transportGO:0051222930.019
immune effector processGO:00022523210.019
t cell differentiationGO:00302171740.019
organelle fissionGO:00482851700.019
fatty acid biosynthetic processGO:0006633410.019
regulation of isoprenoid metabolic processGO:001974710.019
myelinationGO:0042552740.018
organic hydroxy compound metabolic processGO:19016152030.018
positive regulation of intracellular protein transportGO:0090316420.018
positive regulation of protein phosphorylationGO:00019342420.018
leukocyte proliferationGO:00706611720.018
protein ubiquitinationGO:00165671710.018
defecationGO:003042110.018
positive regulation of cytoplasmic transportGO:1903651400.018
sensory perceptionGO:00076002450.018
Human
small molecule biosynthetic processGO:00442831320.018
regulation of t cell proliferationGO:0042129920.018
protein import into nucleusGO:0006606950.018
energy derivation by oxidation of organic compoundsGO:0015980770.018
purine ribonucleoside catabolic processGO:00461302050.018
negative regulation of defense responseGO:0031348770.018
purine ribonucleoside triphosphate catabolic processGO:00092071990.018
cation transmembrane transportGO:00986552660.018
response to uvGO:0009411440.018
proteasomal protein catabolic processGO:0010498980.018
circulatory system processGO:00030131970.017
regulation of lymphocyte anergyGO:000291140.017
camera type eye developmentGO:00430102660.017
cell growthGO:00160491300.017
cell agingGO:0007569350.017
Human
regulation of engulfment of apoptotic cellGO:190107420.017
nucleoside catabolic processGO:00091642060.017
gland developmentGO:00487323300.017
regulation of secretionGO:00510462740.017
neuron apoptotic processGO:00514021420.017
positive regulation of programmed cell deathGO:00430682180.017
sensory organ morphogenesisGO:00905962420.017
alcohol metabolic processGO:00060661160.017
lateral inhibitionGO:004633110.017
positive regulation of secretionGO:00510471300.017
acetyl coa biosynthetic process from pyruvateGO:000608630.017
renal system developmentGO:00720012250.017
regulation of system processGO:00440572000.017
ribonucleoside monophosphate metabolic processGO:0009161800.017
carbohydrate derivative catabolic processGO:19011362310.017
regulation of neuron differentiationGO:00456642810.017
response to inorganic substanceGO:0010035960.017
Worm
purine nucleoside triphosphate catabolic processGO:00091462030.016
regulation of t cell activationGO:00508631700.016
monocarboxylic acid biosynthetic processGO:0072330610.016
cellular response to hormone stimulusGO:00328701500.016
regulation of protein import into nucleusGO:0042306520.016
chromosome segregationGO:0007059480.016
cellular response to organonitrogen compoundGO:00714171450.016
establishment of organelle localizationGO:00516561220.016
posttranscriptional regulation of gene expressionGO:00106081550.016
regulation of blood pressureGO:0008217930.016
connective tissue developmentGO:00614481790.016
skeletal muscle organ developmentGO:00605381630.016
rna processingGO:00063961050.016
negative regulation of cellular amino acid metabolic processGO:004576300.016
regulation of cell activationGO:00508652890.016
regulation of hormone levelsGO:00108172110.016
morphogenesis of embryonic epitheliumGO:00163311590.016
regulation of transferase activityGO:00513382630.015
positive regulation of growthGO:00459271040.015
Worm
muscle fiber developmentGO:0048747760.015
cellular carbohydrate metabolic processGO:00442621190.015
cerebellum developmentGO:0021549770.015
tissue homeostasisGO:00018941150.015
cellular response to abiotic stimulusGO:0071214560.015
regulation of vesicle mediated transportGO:00606271390.015
response to organic cyclic compoundGO:00140701980.015
nuclear importGO:0051170950.015
purine ribonucleoside triphosphate metabolic processGO:00092052200.015
antibacterial peptide biosynthetic processGO:000278020.015
positive regulation of protein localization to nucleusGO:1900182300.015
oxidoreduction coenzyme metabolic processGO:0006733160.015
negative regulation of cellular amine metabolic processGO:003323910.015
positive regulation of cell activationGO:00508671580.015
negative regulation of molecular functionGO:00440922580.015
regulation of kinase activityGO:00435492490.015
phagocytosisGO:0006909660.015
positive regulation of lymphocyte activationGO:00512511400.015
regulation of cellular component biogenesisGO:00440871810.015
regulation of leukocyte proliferationGO:00706631210.015
negative regulation of cell cycle processGO:0010948690.015
purine nucleoside triphosphate metabolic processGO:00091442260.015
regulation of cell cycle processGO:00105641600.015
dendrite developmentGO:00163581150.014
glycosyl compound catabolic processGO:19016582060.014
spermatogenesisGO:00072832840.014
response to molecule of bacterial originGO:00022371430.014
macromolecule methylationGO:00434141200.014
pallium developmentGO:00215431200.014
hindbrain morphogenesisGO:0021575460.014
g protein coupled receptor signaling pathwayGO:00071862430.014
purine nucleoside monophosphate metabolic processGO:0009126810.014
regulation of translationGO:0006417710.014
fatty acid metabolic processGO:00066311210.014
protein localization to membraneGO:00726571080.014
multicellular organismal signalingGO:0035637910.014
positive regulation of cellular catabolic processGO:00313311480.014
regulation of chromosome organizationGO:0033044830.014
positive regulation of t cell activationGO:00508701010.014
regulation of cytokine productionGO:00018172660.014
wound healingGO:00420601570.014
generation of precursor metabolites and energyGO:00060911030.014
peptide secretionGO:00027901140.014
axon ensheathmentGO:0008366760.014
purine ribonucleotide catabolic processGO:00091542080.014
regulation of protein serine threonine kinase activityGO:00719001570.014
regulation of metal ion transportGO:00109591060.014
apoptotic signaling pathwayGO:00971903060.014
regulation of cellular response to growth factor stimulusGO:0090287820.014
regulation of protein secretionGO:0050708820.014
negative regulation of cell activationGO:00508661110.014
urogenital system developmentGO:00016552610.014
regulation of leukocyte differentiationGO:19021051590.014
regulation of cell morphogenesis involved in differentiationGO:00107691510.014
positive regulation of homeostatic processGO:0032846640.014
regulation of lymphocyte proliferationGO:00506701170.014
cellular response to oxidative stressGO:0034599760.014
negative regulation of protein modification processGO:00314001630.014
stress activated mapk cascadeGO:0051403800.013
positive regulation of protein import into nucleusGO:0042307260.013
positive regulation of ion transportGO:0043270650.013
dna repairGO:00062811070.013
thioester biosynthetic processGO:003538470.013
regulation of map kinase activityGO:00434051200.013
regulation of epithelial cell proliferationGO:00506781410.013
mesenchyme developmentGO:00604851520.013
amide transportGO:00428861380.013
atp metabolic processGO:0046034750.013
ensheathment of neuronsGO:0007272760.013
mapk cascadeGO:00001652810.013
regulation of transmembrane transportGO:00347621280.013
locomotory behaviorGO:00076261950.013
response to radiationGO:00093141650.013
sodium ion transportGO:0006814730.013
purine containing compound metabolic processGO:00725213110.013
nadh metabolic processGO:000673410.013
kidney developmentGO:00018222130.013
chemotaxisGO:00069352470.013
synapse assemblyGO:0007416560.013
negative regulation of phosphorus metabolic processGO:00105631840.013
negative regulation of organelle organizationGO:0010639900.013
sulfur compound metabolic processGO:00067901000.012
positive regulation of protein kinase activityGO:00458601440.012
axonogenesisGO:00074092740.012
regulation of proteolysisGO:00301621640.012
regulation of response to drugGO:200102320.012
regulation of transcription factor import into nucleusGO:0042990240.012
carboxylic acid biosynthetic processGO:0046394860.012
p38mapk cascadeGO:003806640.012
thioester metabolic processGO:0035383190.012
purine nucleoside catabolic processGO:00061522050.012
regulation of reactive oxygen species metabolic processGO:2000377400.012
epithelial cell developmentGO:00020641590.012
negative regulation of protein metabolic processGO:00512482820.012
cofactor transportGO:005118140.012
response to extracellular stimulusGO:00099911270.012
cell divisionGO:00513011200.012
regulation of cell cycle phase transitionGO:1901987770.012
carbohydrate homeostasisGO:00335001280.012
positive regulation of cell deathGO:00109422240.012
regulation of protein catabolic processGO:00421761080.012
negative regulation of phosphate metabolic processGO:00459361840.012
regulation of protein complex assemblyGO:0043254830.012
cerebellar cortex developmentGO:0021695480.012
actin cytoskeleton organizationGO:00300362200.012
histone acetylationGO:0016573410.012
nucleoside phosphate biosynthetic processGO:1901293790.012
regulation of protein kinase activityGO:00458592320.012
ear developmentGO:00435832000.012
developmental growth involved in morphogenesisGO:00605601380.012
nucleoside triphosphate catabolic processGO:00091432050.012
skeletal system morphogenesisGO:00487052030.012
purine nucleotide biosynthetic processGO:0006164650.012
regulation of ossificationGO:00302781120.011
positive regulation of apoptotic processGO:00430652170.011
cellular response to lipidGO:00713961450.011
glucose homeostasisGO:00425931280.011
activation of immune responseGO:00022531380.011
positive regulation of fatty acid biosynthetic processGO:004572330.011
innate immune responseGO:00450871570.011
peptidyl lysine modificationGO:0018205770.011
angiogenesisGO:00015252010.011
gastrulationGO:00073691160.011
germ cell developmentGO:00072811850.011
carboxylic acid catabolic processGO:0046395510.011
negative regulation of immune effector processGO:0002698550.011
cellular response to dna damage stimulusGO:00069742070.011
purine nucleotide catabolic processGO:00061952110.011
immune response activating signal transductionGO:00027571160.011
negative regulation of cell cycleGO:00457861230.011
positive regulation of mitochondrion organizationGO:0010822170.011
cerebellum morphogenesisGO:0021587420.011
positive regulation of glial cell proliferationGO:006025240.011
sulfur compound biosynthetic processGO:0044272370.011
response to nutrient levelsGO:00316671090.011
cellular response to molecule of bacterial originGO:0071219830.011
regulation of response to woundingGO:19030341890.011
peptide transportGO:00158331330.011
stem cell differentiationGO:00488632680.011
muscle system processGO:00030121410.011
response to transforming growth factor betaGO:0071559880.011
response to lipopolysaccharideGO:00324961280.011
modification dependent macromolecule catabolic processGO:00436321330.011
nuclear divisionGO:00002801580.011
regulation of lipid metabolic processGO:00192161180.011
acetyl coa biosynthetic processGO:000608550.011
mitochondrion degradationGO:000042230.011
regulation of reactive oxygen species biosynthetic processGO:190342620.011
response to light stimulusGO:00094161350.011
negative regulation of phosphorylationGO:00423261660.011
blood circulationGO:00080151950.010
male gamete generationGO:00482322850.010
sequestering of calcium ionGO:0051208180.010
regulation of multi organism processGO:00439001110.010
multicellular organismal agingGO:0010259240.010
protein targeting to mitochondrionGO:000662660.010
single organism cell adhesionGO:00986021560.010
gtp catabolic processGO:00061841430.010
ubiquitin dependent protein catabolic processGO:00065111290.010
positive regulation of chromosome organizationGO:2001252330.010
regulation of neuron apoptotic processGO:00435231220.010
placenta developmentGO:00018901400.010
central nervous system neuron differentiationGO:00219531620.010
bmp signaling pathwayGO:0030509930.010
regulation of cell motilityGO:20001452360.010
stem cell developmentGO:00488642190.010
regulation of inflammatory responseGO:00507271470.010
organic hydroxy compound biosynthetic processGO:1901617770.010
negative regulation of cellular protein metabolic processGO:00322692470.010
regulation of endocytosisGO:0030100690.010
myotube differentiationGO:00149021050.010
regulation of peptidyl threonine phosphorylationGO:0010799120.010
protein localization to nucleusGO:00345041210.010
regulation of mitotic cell cycleGO:00073461260.010
ribonucleoside triphosphate catabolic processGO:00092031990.010
regulation of mitochondrial translationGO:007012930.010
negative regulation of mitotic cell cycleGO:0045930580.010
carbohydrate derivative biosynthetic processGO:19011371830.010

Opa1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.078
disease of anatomical entityDOID:700.078
central nervous system diseaseDOID:33100.042
inherited metabolic disorderDOID:65500.028
disease of metabolismDOID:001466700.028
neurodegenerative diseaseDOID:128900.026
sensory system diseaseDOID:005015500.017
eye and adnexa diseaseDOID:149200.017
retinal diseaseDOID:567900.012
eye diseaseDOID:561400.012
cancerDOID:16200.010
disease of cellular proliferationDOID:1456600.010
organ system cancerDOID:005068600.010