IMP: Integrative Multi-species Prediction

Mus musculus

60 known processes

Gpi1

glucose phosphate isomerase 1

(Aliases: MGC113776,MF,NK/GPI,Gpi,Gpi-1,Amf,Gpi-1r,Gpi-1s,NK,Gpi-1t,Org,Gpi1-r,Gpi1-s,Gpi1-t,Gpi1s)

Entrez: 14751
Ensembl: ENSMUSG00000036427
UniProtKB: P06745

Process Predictions
Disease Predictions

Gpi1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
glycolytic process	GO:0006096	20	1.000
pyruvate metabolic process	GO:0006090	28	0.995
carbohydrate catabolic process	GO:0016052	32	0.993
ribonucleoside monophosphate biosynthetic process	GO:0009156	9	0.974
hexose catabolic process	GO:0019320	3	0.968
myosin filament organization	GO:0031033	3	0.956
generation of precursor metabolites and energy	GO:0006091	103	0.911
carbohydrate metabolic process	GO:0005975	230	0.821
striated muscle myosin thick filament assembly	GO:0071688	1	0.759
hexose metabolic process	GO:0019318	98	0.618
purine nucleoside biosynthetic process	GO:0042451	19	0.585
monocarboxylic acid metabolic process	GO:0032787	191	0.582
ribonucleoside biosynthetic process	GO:0042455	21	0.568
ribose phosphate biosynthetic process	GO:0046390	59	0.557
pigmentation	GO:0043473	71	0.507
purine nucleoside monophosphate biosynthetic process	GO:0009127	9	0.430
purine nucleotide biosynthetic process	GO:0006164	65	0.427
pentose phosphate shunt	GO:0006098	2	0.421
atp metabolic process	GO:0046034	75	0.417
monosaccharide metabolic process	GO:0005996	106	0.413
sperm motility	GO:0030317	47	0.387
segmentation	GO:0035282	93	0.377
glucose metabolic process	GO:0006006	92	0.343
nucleoside monophosphate metabolic process	GO:0009123	85	0.338
nucleoside phosphate biosynthetic process	GO:1901293	79	0.335
response to lipopolysaccharide	GO:0032496	128	0.335
nadph regeneration	GO:0006740	2	0.334
muscle cell development	GO:0055001	133	0.329
response to nicotine	GO:0035094	6	0.328
response to decreased oxygen levels	GO:0036293	59	0.309
myofibril assembly	GO:0030239	34	0.305
purine ribonucleotide metabolic process	GO:0009150	290	0.303
pyridine nucleotide metabolic process	GO:0019362	12	0.293
lactate biosynthetic process	GO:0019249	4	0.293
somite development	GO:0061053	81	0.287
carbohydrate derivative biosynthetic process	GO:1901137	183	0.287
carbohydrate phosphorylation	GO:0046835	15	0.283
nucleoside phosphate metabolic process	GO:0006753	338	0.266
cellular component assembly involved in morphogenesis	GO:0010927	139	0.262
oxidation reduction process	GO:0055114	342	0.251
nitrogen compound transport	GO:0071705	271	0.246
nucleoside metabolic process	GO:0009116	246	0.231
glucose catabolic process	GO:0006007	3	0.227
striated muscle contraction	GO:0006941	45	0.223
nucleobase containing small molecule metabolic process	GO:0055086	352	0.221
regulation of cell cycle phase transition	GO:1901987	77	0.218
ribonucleotide metabolic process	GO:0009259	291	0.202
purine ribonucleoside metabolic process	GO:0046128	241	0.200
purine containing compound metabolic process	GO:0072521	311	0.194
positive regulation of hormone secretion	GO:0046887	38	0.190
purine nucleoside triphosphate biosynthetic process	GO:0009145	7	0.185
cellular homeostasis	GO:0019725	240	0.184
response to organic cyclic compound	GO:0014070	198	0.179
nucleoside biosynthetic process	GO:0009163	21	0.174
anatomical structure homeostasis	GO:0060249	145	0.170
glycosyl compound biosynthetic process	GO:1901659	21	0.158
cellular amide metabolic process	GO:0043603	58	0.156
insulin secretion	GO:0030073	89	0.151
cellular protein complex assembly	GO:0043623	116	0.151
midbrain development	GO:0030901	35	0.149
negative regulation of cell cycle process	GO:0010948	69	0.147
protein targeting	GO:0006605	143	0.146
organophosphate biosynthetic process	GO:0090407	122	0.144
response to heat	GO:0009408	27	0.140
negative regulation of cellular protein metabolic process	GO:0032269	247	0.140
mitotic cell cycle	GO:0000278	195	0.132
regulation of mitotic cell cycle	GO:0007346	126	0.130
cellular response to external stimulus	GO:0071496	88	0.124
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.121
purine ribonucleoside biosynthetic process	GO:0046129	19	0.120
negative regulation of mitotic cell cycle phase transition	GO:1901991	45	0.119
purine ribonucleoside monophosphate metabolic process	GO:0009167	80	0.119
regulation of cell cycle	GO:0051726	281	0.116
somitogenesis	GO:0001756	69	0.114
regulation of hormone levels	GO:0010817	211	0.113
positive regulation of peptide secretion	GO:0002793	33	0.113
nucleotide metabolic process	GO:0009117	332	0.112
axonogenesis	GO:0007409	274	0.112
purine containing compound biosynthetic process	GO:0072522	70	0.112
response to steroid hormone	GO:0048545	56	0.111
ribonucleoside monophosphate metabolic process	GO:0009161	80	0.109
purine nucleotide metabolic process	GO:0006163	302	0.109
ribose phosphate metabolic process	GO:0019693	291	0.098
regulation of translation	GO:0006417	71	0.097
purine ribonucleotide biosynthetic process	GO:0009152	59	0.096
organic hydroxy compound biosynthetic process	GO:1901617	77	0.094
negative regulation of cell cycle phase transition	GO:1901988	48	0.094
cellular amino acid metabolic process	GO:0006520	103	0.094
glucose homeostasis	GO:0042593	128	0.088
purine nucleoside monophosphate metabolic process	GO:0009126	81	0.086
nucleoside triphosphate metabolic process	GO:0009141	230	0.085
regulation of peptide transport	GO:0090087	91	0.084
actomyosin structure organization	GO:0031032	56	0.081
muscle system process	GO:0003012	141	0.080
organonitrogen compound biosynthetic process	GO:1901566	192	0.079
maintenance of location	GO:0051235	89	0.079
positive regulation of apoptotic process	GO:0043065	217	0.078
energy derivation by oxidation of organic compounds	GO:0015980	77	0.077
mitotic cell cycle checkpoint	GO:0007093	31	0.077
purine ribonucleoside triphosphate biosynthetic process	GO:0009206	6	0.075
myosin filament assembly	GO:0031034	2	0.074
regulation of cell shape	GO:0008360	39	0.074
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.071
purine nucleoside metabolic process	GO:0042278	241	0.071
fructose 6 phosphate metabolic process	GO:0006002	1	0.067
reproductive behavior	GO:0019098	32	0.066
purine ribonucleoside monophosphate biosynthetic process	GO:0009168	9	0.065
regulation of protein kinase activity	GO:0045859	232	0.065
monocarboxylic acid biosynthetic process	GO:0072330	61	0.059
response to organonitrogen compound	GO:0010243	246	0.058
nucleotide biosynthetic process	GO:0009165	78	0.058
response to molecule of bacterial origin	GO:0002237	143	0.057
cellular aldehyde metabolic process	GO:0006081	12	0.053
positive regulation of cell death	GO:0010942	224	0.053
ribonucleotide biosynthetic process	GO:0009260	59	0.052
substantia nigra development	GO:0021762	2	0.051
negative regulation of mitotic cell cycle	GO:0045930	58	0.051
nucleoside monophosphate biosynthetic process	GO:0009124	12	0.050
organelle assembly	GO:0070925	177	0.050
dna damage checkpoint	GO:0000077	26	0.050
cellular response to extracellular stimulus	GO:0031668	81	0.045
alpha amino acid metabolic process	GO:1901605	59	0.043
positive regulation of peptide hormone secretion	GO:0090277	31	0.043
cellular response to dna damage stimulus	GO:0006974	207	0.043
oxidoreduction coenzyme metabolic process	GO:0006733	16	0.042
endomembrane system organization	GO:0010256	147	0.039
positive regulation of cysteine type endopeptidase activity	GO:2001056	39	0.038
hormone secretion	GO:0046879	128	0.038
negative regulation of peptide secretion	GO:0002792	16	0.037
muscle contraction	GO:0006936	101	0.037
dna integrity checkpoint	GO:0031570	28	0.036
regulation of cellular amino acid metabolic process	GO:0006521	5	0.036
regulation of cellular catabolic process	GO:0031329	242	0.035
cellular amine metabolic process	GO:0044106	44	0.035
heterocycle catabolic process	GO:0046700	280	0.033
regulation of cellular ketone metabolic process	GO:0010565	66	0.033
macromolecule catabolic process	GO:0009057	281	0.033
regulation of cellular amine metabolic process	GO:0033238	20	0.033
myotube differentiation	GO:0014902	105	0.032
tricarboxylic acid metabolic process	GO:0072350	5	0.032
amide transport	GO:0042886	138	0.032
regulation of mitotic cell cycle phase transition	GO:1901990	73	0.032
regulation of peptide secretion	GO:0002791	77	0.032
nadh metabolic process	GO:0006734	1	0.031
nadp metabolic process	GO:0006739	6	0.031
multicellular organismal reproductive behavior	GO:0033057	23	0.031
placenta development	GO:0001890	140	0.031
carboxylic acid biosynthetic process	GO:0046394	86	0.031
ribonucleoside metabolic process	GO:0009119	245	0.030
ribonucleoside triphosphate biosynthetic process	GO:0009201	6	0.029
translation	GO:0006412	93	0.029
regulation of secretion	GO:0051046	274	0.029
carbohydrate homeostasis	GO:0033500	128	0.028
cytoplasmic transport	GO:0016482	234	0.028
lipid localization	GO:0010876	126	0.028
cellular carbohydrate catabolic process	GO:0044275	15	0.027
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.027
multicellular organismal aging	GO:0010259	24	0.027	Worm
regulation of coenzyme metabolic process	GO:0051196	4	0.026
negative regulation of cell cycle	GO:0045786	123	0.026
regulation of endopeptidase activity	GO:0052548	89	0.026
amine metabolic process	GO:0009308	45	0.026
response to temperature stimulus	GO:0009266	55	0.025
striated muscle cell development	GO:0055002	125	0.025
response to hypoxia	GO:0001666	58	0.025
protein localization to membrane	GO:0072657	108	0.025
apoptotic signaling pathway	GO:0097190	306	0.024
negative regulation of molecular function	GO:0044092	258	0.024
regionalization	GO:0003002	337	0.023
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.023
renal system development	GO:0072001	225	0.022
inorganic cation transmembrane transport	GO:0098662	207	0.022
response to estrogen	GO:0043627	24	0.022
response to alkaloid	GO:0043279	34	0.021
organic hydroxy compound metabolic process	GO:1901615	203	0.021
response to oxygen levels	GO:0070482	62	0.021
positive regulation of cellular amine metabolic process	GO:0033240	5	0.020
dicarboxylic acid transport	GO:0006835	29	0.020
regulation of glycolytic process	GO:0006110	10	0.020
mitotic cell cycle process	GO:1903047	159	0.020
protein modification by small protein conjugation	GO:0032446	187	0.020
multi multicellular organism process	GO:0044706	109	0.020
dephosphorylation	GO:0016311	129	0.020
aromatic compound catabolic process	GO:0019439	286	0.019
purine ribonucleotide catabolic process	GO:0009154	208	0.019
fructose metabolic process	GO:0006000	1	0.019
genitalia development	GO:0048806	37	0.019
regulation of transferase activity	GO:0051338	263	0.019
cellular lipid metabolic process	GO:0044255	323	0.019
lung development	GO:0030324	164	0.018
cell fate commitment	GO:0045165	210	0.018
cell redox homeostasis	GO:0045454	6	0.018
cellular ketone metabolic process	GO:0042180	84	0.018
regulation of cytokine production	GO:0001817	266	0.017
positive regulation of kinase activity	GO:0033674	155	0.017
determination of adult lifespan	GO:0008340	11	0.017	Worm
negative regulation of protein metabolic process	GO:0051248	282	0.017
protein catabolic process	GO:0030163	221	0.017
skin development	GO:0043588	220	0.017
gonad development	GO:0008406	141	0.017
sensory perception	GO:0007600	245	0.017
cellular response to organonitrogen compound	GO:0071417	145	0.017
protein processing	GO:0016485	163	0.017
muscle cell differentiation	GO:0042692	261	0.017
regulation of protein localization	GO:0032880	231	0.017
positive regulation of growth	GO:0045927	104	0.016
cell adhesion	GO:0007155	329	0.016
multi organism reproductive behavior	GO:0044705	29	0.015
cellular response to osmotic stress	GO:0071470	7	0.015
epithelial cell development	GO:0002064	159	0.015
cell cycle checkpoint	GO:0000075	47	0.015
multi organism behavior	GO:0051705	62	0.015
organelle localization	GO:0051640	179	0.015
cellular response to hormone stimulus	GO:0032870	150	0.015
peptidyl proline hydroxylation	GO:0019511	3	0.014
establishment of pigment granule localization	GO:0051905	12	0.014
regulation of apoptotic signaling pathway	GO:2001233	197	0.014
neuron neuron synaptic transmission	GO:0007270	69	0.014
sequestering of metal ion	GO:0051238	19	0.014
peptidyl amino acid modification	GO:0018193	336	0.014
protein oligomerization	GO:0051259	67	0.014
spermatogenesis	GO:0007283	284	0.014
peptide transport	GO:0015833	133	0.014
multicellular organismal homeostasis	GO:0048871	164	0.014
learning or memory	GO:0007611	148	0.014
cell type specific apoptotic process	GO:0097285	268	0.013
circulatory system process	GO:0003013	197	0.013
positive regulation of nervous system development	GO:0051962	221	0.013
protein localization to plasma membrane	GO:0072659	57	0.013
cell maturation	GO:0048469	127	0.013
histone modification	GO:0016570	159	0.013
carbohydrate biosynthetic process	GO:0016051	74	0.013
protein ubiquitination	GO:0016567	171	0.013
response to starvation	GO:0042594	65	0.013
toxin transport	GO:1901998	38	0.013
epithelial tube morphogenesis	GO:0060562	303	0.013
transmembrane transport	GO:0055085	412	0.013
regulation of kinase activity	GO:0043549	249	0.013
cellular modified amino acid metabolic process	GO:0006575	63	0.013
positive regulation of hydrolase activity	GO:0051345	148	0.012
establishment of vesicle localization	GO:0051650	81	0.012
cellular response to lipid	GO:0071396	145	0.012
peptide hormone secretion	GO:0030072	109	0.012
reactive oxygen species metabolic process	GO:0072593	84	0.012
positive regulation of cell projection organization	GO:0031346	95	0.012
forebrain development	GO:0030900	302	0.012
carbohydrate derivative catabolic process	GO:1901136	231	0.012
cation homeostasis	GO:0055080	212	0.012
peptidyl tyrosine modification	GO:0018212	145	0.012
glycosyl compound metabolic process	GO:1901657	246	0.012
protein modification by small protein conjugation or removal	GO:0070647	207	0.012
lateral inhibition	GO:0046331	1	0.011
regulation of secretion by cell	GO:1903530	249	0.011
regulation of protein serine threonine kinase activity	GO:0071900	157	0.011
cellular ion homeostasis	GO:0006873	165	0.011
anion transport	GO:0006820	177	0.011
positive regulation of organelle organization	GO:0010638	128	0.011
gluconeogenesis	GO:0006094	39	0.011
response to inorganic substance	GO:0010035	96	0.011
respiratory system development	GO:0060541	190	0.011
plasma membrane organization	GO:0007009	90	0.011
respiratory tube development	GO:0030323	167	0.011
mapk cascade	GO:0000165	281	0.011
cellular nitrogen compound catabolic process	GO:0044270	280	0.011
energy reserve metabolic process	GO:0006112	39	0.011
lipid biosynthetic process	GO:0008610	179	0.011
positive regulation of protein phosphorylation	GO:0001934	242	0.011
morphogenesis of a branching epithelium	GO:0061138	193	0.011
organonitrogen compound catabolic process	GO:1901565	264	0.011
galactose metabolic process	GO:0006012	4	0.011
fat cell differentiation	GO:0045444	160	0.011
positive regulation of protein modification process	GO:0031401	299	0.011
cation transport	GO:0006812	399	0.010
positive regulation of reactive oxygen species metabolic process	GO:2000379	11	0.010
positive regulation of protein kinase activity	GO:0045860	144	0.010
polysaccharide metabolic process	GO:0005976	39	0.010
tissue homeostasis	GO:0001894	115	0.010
cytokine production	GO:0001816	319	0.010
glucan metabolic process	GO:0044042	32	0.010

Gpi1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability	Func Analog Org
disease of metabolism	DOID:0014667	0.263
disease of anatomical entity	DOID:7	0.090	Human
nervous system disease	DOID:863	0.090
carbohydrate metabolism disease	DOID:0050013	0.050
acquired metabolic disease	DOID:0060158	0.050
neurodegenerative disease	DOID:1289	0.020
central nervous system disease	DOID:331	0.020
glucose metabolism disease	DOID:4194	0.013
musculoskeletal system disease	DOID:17	0.012
immune system disease	DOID:2914	0.011	Human

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