Mus musculus

111 known processes

Hexa

hexosaminidase A

(Aliases: Hex-1)

Hexa biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
lysosome organizationGO:0007040210.991
lytic vacuole organizationGO:0080171210.972
glycolipid metabolic processGO:0006664250.972
glycosphingolipid catabolic processGO:004647950.967
membrane lipid metabolic processGO:0006643530.930
vacuole organizationGO:0007033380.914
male courtship behaviorGO:000804920.895
Mouse
glycolipid catabolic processGO:001937750.877
liposaccharide metabolic processGO:1903509270.866
membrane lipid catabolic processGO:004646680.850
carbohydrate catabolic processGO:0016052320.831
Mouse
cellular lipid catabolic processGO:0044242520.685
cellular lipid metabolic processGO:00442553230.673
fertilizationGO:00095661270.614
Mouse
courtship behaviorGO:000761950.587
Mouse
astrocyte cell migrationGO:004361530.561
Mouse
aminoglycan metabolic processGO:0006022340.557
lipid localizationGO:00108761260.442
neuronal action potentialGO:0019228540.440
carbohydrate metabolic processGO:00059752300.424
Mouse
glycosaminoglycan metabolic processGO:0030203340.396
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.378
oligosaccharide metabolic processGO:0009311110.364
Mouse
oligosaccharide catabolic processGO:000931320.345
Mouse
ceramide catabolic processGO:004651470.330
myelinationGO:0042552740.312
organonitrogen compound catabolic processGO:19015652640.310
smad protein signal transductionGO:0060395210.296
multicellular organismal signalingGO:0035637910.288
neuromuscular processGO:0050905990.281
neuromuscular process controlling balanceGO:0050885590.273
sensory perception of soundGO:0007605970.269
regulation of membrane potentialGO:00423911920.258
regulation of cell shapeGO:0008360390.257
Mouse
single fertilizationGO:0007338820.245
Mouse
maintenance of locationGO:0051235890.245
neuromuscular process controlling postureGO:0050884140.221
cellular homeostasisGO:00197252400.197
Mouse
cellular metal ion homeostasisGO:00068751510.193
Mouse
calcium ion homeostasisGO:00550741270.192
Mouse
organelle assemblyGO:00709251770.177
cation homeostasisGO:00550802120.176
Mouse
leukocyte mediated immunityGO:00024431740.174
metal ion homeostasisGO:00550651890.174
Mouse
sensory perceptionGO:00076002450.164
adult walking behaviorGO:0007628410.157
germ cell developmentGO:00072811850.156
Mouse
carbohydrate derivative catabolic processGO:19011362310.154
matingGO:0007618270.148
Mouse
action potentialGO:0001508780.148
cellular ion homeostasisGO:00068731650.137
Mouse
natural killer cell degranulationGO:004332030.137
ceramide metabolic processGO:0006672310.128
striated muscle tissue developmentGO:00147062930.128
lymphocyte mediated immunityGO:00024491390.127
locomotory behaviorGO:00076261950.127
leukocyte mediated cytotoxicityGO:0001909620.120
cellular divalent inorganic cation homeostasisGO:00725031270.110
Mouse
axon ensheathmentGO:0008366760.107
sphingolipid metabolic processGO:0006665450.107
lipid storageGO:0019915360.099
cellular calcium ion homeostasisGO:00068741190.098
Mouse
organophosphate biosynthetic processGO:00904071220.093
Mouse
transmission of nerve impulseGO:0019226760.088
adult behaviorGO:00305341350.085
gliogenesisGO:00420631410.083
Mouse
cellular component assembly involved in morphogenesisGO:00109271390.082
divalent inorganic cation homeostasisGO:00725071380.081
Mouse
regulation of hormone levelsGO:00108172110.078
protein catabolic processGO:00301632210.078
multi organism reproductive behaviorGO:0044705290.076
Mouse
multi organism behaviorGO:0051705620.072
Mouse
immune effector processGO:00022523210.072
kidney developmentGO:00018222130.068
regulation of neuron apoptotic processGO:00435231220.067
muscle tissue developmentGO:00605373080.066
positive regulation of secretion by cellGO:19035321140.060
macromolecule catabolic processGO:00090572810.060
developmental growth involved in morphogenesisGO:00605601380.057
axonogenesisGO:00074092740.055
cellular response to thyroid hormone stimulusGO:009706710.055
adult locomotory behaviorGO:0008344910.054
cellular chemical homeostasisGO:00550822150.053
Mouse
gland developmentGO:00487323300.052
reproductive behaviorGO:0019098320.049
Mouse
t cell mediated cytotoxicityGO:0001913260.049
reactive oxygen species metabolic processGO:0072593840.048
cytoplasmic transportGO:00164822340.047
oogenesisGO:0048477560.045
Mouse
regulation of cellular amino acid metabolic processGO:000652150.044
n acetylglucosamine metabolic processGO:000604430.043
regulation of angiotensin metabolic processGO:006017740.042
camera type eye developmentGO:00430102660.042
antigen processing and presentation of exogenous peptide antigenGO:0002478210.042
male gamete generationGO:00482322850.042
apoptotic signaling pathwayGO:00971903060.041
adaptive immune responseGO:00022501550.039
morphogenesis of a branching epitheliumGO:00611381930.039
limb morphogenesisGO:00351081490.038
positive regulation of cellular amine metabolic processGO:003324050.037
regulation of defense responseGO:00313472330.037
urogenital system developmentGO:00016552610.037
regulation of secretionGO:00510462740.036
regulation of cellular ketone metabolic processGO:0010565660.036
male gonad developmentGO:0008584880.035
regulation of cellular amine metabolic processGO:0033238200.035
ameboidal type cell migrationGO:00016671280.035
multicellular organismal homeostasisGO:00488711640.034
neuron projection extensionGO:1990138640.034
muscle cell developmentGO:00550011330.034
blood vessel morphogenesisGO:00485142850.033
response to extracellular stimulusGO:00099911270.033
regulation of angiotensin levels in bloodGO:000200240.032
cell killingGO:0001906670.032
vesicle organizationGO:0016050600.032
tissue remodelingGO:00487711020.032
regulation of system processGO:00440572000.031
membrane lipid biosynthetic processGO:0046467320.031
formation of radial glial scaffoldsGO:002194340.031
positive regulation of exocytosisGO:0045921200.031
regulation of cellular component biogenesisGO:00440871810.031
cellular ketone metabolic processGO:0042180840.030
regulation of hormone secretionGO:0046883880.030
skeletal system morphogenesisGO:00487052030.030
cell growthGO:00160491300.029
regulation of apoptotic signaling pathwayGO:20012331970.029
natural killer cell activation involved in immune responseGO:0002323100.029
muscle contractionGO:00069361010.029
skeletal system developmentGO:00015013560.029
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.029
regulation of natural killer cell activationGO:0032814220.029
positive regulation of cellular amino acid metabolic processGO:004576430.029
skeletal muscle organ developmentGO:00605381630.028
positive regulation of secretionGO:00510471300.028
platelet derived growth factor receptor alpha signaling pathwayGO:003579030.028
striated muscle contractionGO:0006941450.028
ion transmembrane transportGO:00342203610.028
metanephric glomerular visceral epithelial cell developmentGO:007224920.028
cell recognitionGO:0008037830.028
regulation of secretion by cellGO:19035302490.028
regulation of peptidase activityGO:0052547960.027
epithelial tube morphogenesisGO:00605623030.027
cellular amino acid metabolic processGO:00065201030.027
endocytosisGO:00068971680.027
positive regulation of cell developmentGO:00107202370.027
retina development in camera type eyeGO:00600411190.027
regulation of lymphocyte activationGO:00512492400.027
sterol homeostasisGO:0055092450.027
regulation of lymphocyte mediated immunityGO:0002706840.027
chemotaxisGO:00069352470.027
hormone metabolic processGO:0042445860.027
development of primary male sexual characteristicsGO:0046546880.026
regulation of cell motilityGO:20001452360.026
cell chemotaxisGO:0060326810.026
lymphocyte proliferationGO:00466511640.026
cardiac muscle tissue developmentGO:00487381300.026
calcium ion transportGO:00068161590.026
male sex differentiationGO:00466611090.026
cell type specific apoptotic processGO:00972852680.025
inorganic cation transmembrane transportGO:00986622070.025
tissue migrationGO:0090130680.025
circulatory system processGO:00030131970.025
glycosphingolipid metabolic processGO:0006687180.025
female gamete generationGO:0007292740.025
Mouse
inflammatory responseGO:00069542440.025
monosaccharide metabolic processGO:00059961060.025
regulation of vesicle mediated transportGO:00606271390.025
regulation of vascular smooth muscle contractionGO:000305610.024
lung developmentGO:00303241640.024
blood circulationGO:00080151950.024
anatomical structure homeostasisGO:00602491450.024
negative regulation of cellular protein metabolic processGO:00322692470.024
regulation of hydrolase activityGO:00513362460.023
learningGO:0007612980.023
hindbrain developmentGO:00309021280.023
regulation of intracellular transportGO:00323861590.023
cellular response to oxidative stressGO:0034599760.023
renal system developmentGO:00720012250.023
negative regulation of neuron deathGO:1901215980.022
transmembrane transportGO:00550854120.022
water soluble vitamin biosynthetic processGO:004236430.022
posttranscriptional regulation of gene expressionGO:00106081550.022
morphogenesis of a branching structureGO:00017632030.022
sphingosine metabolic processGO:000667040.022
regulation of regulated secretory pathwayGO:1903305200.022
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.022
metencephalon developmentGO:0022037890.021
regulation of epithelial cell proliferationGO:00506781410.021
antigen processing and presentation of exogenous peptide antigen via mhc class iiGO:0019886140.021
antigen processing and presentation of exogenous antigenGO:0019884260.021
negative regulation of protein phosphorylationGO:00019331260.021
leukocyte activation involved in immune responseGO:00023661260.021
regulation of cytoplasmic transportGO:19036491120.021
positive regulation of nervous system developmentGO:00519622210.021
extracellular matrix organizationGO:00301981470.021
regulation of protein serine threonine kinase activityGO:00719001570.021
carboxylic acid biosynthetic processGO:0046394860.021
regulation of cellular response to stressGO:00801351590.021
exocytosisGO:00068871210.020
small gtpase mediated signal transductionGO:0007264970.020
extracellular structure organizationGO:00430621480.020
organic acid biosynthetic processGO:0016053860.020
muscle system processGO:00030121410.020
cellular amine metabolic processGO:0044106440.020
regulation of leukocyte mediated immunityGO:00027031040.020
muscle cell differentiationGO:00426922610.020
regulation of establishment of protein localizationGO:00702011810.020
microtubule based movementGO:0007018840.020
cellular response to hormone stimulusGO:00328701500.019
cerebellum developmentGO:0021549770.019
multicellular organismal catabolic processGO:004424370.019
intracellular cholesterol transportGO:003236730.019
regulation of leukocyte mediated cytotoxicityGO:0001910380.019
negative regulation of platelet derived growth factor receptor alpha signaling pathwayGO:200058420.019
regulation of blood vessel remodelingGO:006031230.019
regulation of microtubule based processGO:0032886520.019
striated muscle cell developmentGO:00550021250.019
positive regulation of programmed cell deathGO:00430682180.019
cell migration involved in kidney developmentGO:003578730.018
antigen processing and presentation of peptide antigenGO:0048002290.018
rho protein signal transductionGO:0007266320.018
regulation of transferase activityGO:00513382630.018
negative regulation of neuron differentiationGO:00456651010.018
regulation of blood pressureGO:0008217930.018
intrinsic apoptotic signaling pathwayGO:00971931320.018
positive regulation of cell motilityGO:20001471160.018
regulation of response to woundingGO:19030341890.018
t cell activationGO:00421102890.018
phagolysosome assemblyGO:000184530.018
angiogenesisGO:00015252010.018
amine metabolic processGO:0009308450.018
multicellular organismal metabolic processGO:0044236280.018
neuron apoptotic processGO:00514021420.017
glycosylceramide metabolic processGO:000667740.017
glucosamine containing compound metabolic processGO:190107130.017
ras protein signal transductionGO:0007265770.017
developmental maturationGO:00217001930.017
cell substrate adhesionGO:00315891300.017
ribonucleotide metabolic processGO:00092592910.017
regulation of cell projection organizationGO:00313442060.017
negative regulation of response to woundingGO:1903035770.017
response to oxidative stressGO:00069791230.017
heterocycle catabolic processGO:00467002800.017
positive regulation of immune effector processGO:00026991070.017
regulation of cell activationGO:00508652890.017
cardiac muscle contractionGO:0060048320.017
regulation of neuron projection developmentGO:00109751690.017
nuclear divisionGO:00002801580.016
positive regulation of protein modification processGO:00314012990.016
oxidation reduction processGO:00551143420.016
negative regulation of phosphorylationGO:00423261660.016
hexose metabolic processGO:0019318980.016
regulation of anatomical structure sizeGO:00900661780.016
carbohydrate homeostasisGO:00335001280.016
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188540.016
positive regulation of mapk cascadeGO:00434101700.016
epithelium migrationGO:0090132630.016
ketone catabolic processGO:004218230.016
light adaptionGO:003636720.016
nucleotide metabolic processGO:00091173320.016
negative regulation of intracellular signal transductionGO:19025321670.016
positive regulation of behaviorGO:0048520400.016
regulation of neurotransmitter levelsGO:0001505870.016
hypothalamic tangential migration using cell axon interactionsGO:002185630.016
regulation of metanephric mesenchymal cell migrationGO:200058920.016
natural killer cell mediated immunityGO:0002228290.015
regulation of protein kinase activityGO:00458592320.015
neuron projection guidanceGO:00974851410.015
cation transmembrane transportGO:00986552660.015
positive regulation of hormone secretionGO:0046887380.015
negative regulation of mapk cascadeGO:0043409650.015
protein localization to organelleGO:00333651850.015
negative regulation of protein metabolic processGO:00512482820.015
purine nucleoside catabolic processGO:00061522050.015
regulation of cellular catabolic processGO:00313292420.015
purine ribonucleoside triphosphate metabolic processGO:00092052200.015
regulation of map kinase activityGO:00434051200.015
positive regulation of hydrolase activityGO:00513451480.015
appendage morphogenesisGO:00351071490.015
intracellular sterol transportGO:003236630.015
positive regulation of lymphocyte mediated immunityGO:0002708620.015
regulation of protein localizationGO:00328802310.015
negative regulation of neuron apoptotic processGO:0043524920.015
intracellular lipid transportGO:003236530.015
learning or memoryGO:00076111480.015
negative regulation of transferase activityGO:0051348850.015
response to organonitrogen compoundGO:00102432460.014
reactive oxygen species biosynthetic processGO:190340980.014
regionalizationGO:00030023370.014
regulation of angiogenesisGO:0045765810.014
regulation of cell cycleGO:00517262810.014
positive regulation of apoptotic processGO:00430652170.014
pericardium developmentGO:0060039160.014
cardiocyte differentiationGO:0035051870.014
organophosphate catabolic processGO:00464342320.014
regulation of protein stabilityGO:0031647520.014
purine nucleoside metabolic processGO:00422782410.014
negative regulation of protein modification processGO:00314001630.014
cellular carbohydrate metabolic processGO:00442621190.014
fat cell differentiationGO:00454441600.014
negative regulation of cellular component organizationGO:00511291940.014
substrate dependent cell migration cell extensionGO:000693040.014
negative regulation of phosphate metabolic processGO:00459361840.014
glucose homeostasisGO:00425931280.013
respiratory tube developmentGO:00303231670.013
regulation of natural killer cell mediated cytotoxicityGO:0042269190.013
ribonucleoside metabolic processGO:00091192450.013
cellular protein catabolic processGO:00442571550.013
purine ribonucleoside triphosphate catabolic processGO:00092071990.013
blastocyst hatchingGO:000183540.013
synaptic vesicle primingGO:001608280.013
heart morphogenesisGO:00030071780.013
exocrine system developmentGO:0035272450.013
positive regulation of cytokine productionGO:00018191740.013
embryonic organ morphogenesisGO:00485622760.013
purine containing compound metabolic processGO:00725213110.013
negative regulation of phosphorus metabolic processGO:00105631840.013
microtubule based processGO:00070172360.013
ossificationGO:00015032160.013
visual behaviorGO:0007632450.013
sterol transportGO:0015918380.013
regulation of exocytosisGO:0017157610.013
lipid catabolic processGO:0016042690.013
regulation of mapk cascadeGO:00434082480.013
actomyosin structure organizationGO:0031032560.013
metanephric glomerular epithelial cell developmentGO:007231320.013
regulation of systemic arterial blood pressure by carotid body chemoreceptor signalingGO:000302710.013
nucleoside triphosphate metabolic processGO:00091412300.013
regulated secretory pathwayGO:0045055320.013
stem cell differentiationGO:00488632680.013
cellular response to organonitrogen compoundGO:00714171450.012
negative regulation of molecular functionGO:00440922580.012
metanephric mesenchymal cell migrationGO:003578920.012
multicellular organismal agingGO:0010259240.012
divalent metal ion transportGO:00708381720.012
peptide metabolic processGO:0006518460.012
regulation of protein transportGO:00512231630.012
vasodilationGO:0042311280.012
appendage developmentGO:00487361660.012
antigen processing and presentationGO:0019882470.012
spermatogenesisGO:00072832840.012
l ascorbic acid metabolic processGO:001985240.012
superoxide metabolic processGO:0006801270.012
sensory system developmentGO:004888030.012
mapk cascadeGO:00001652810.012
myeloid leukocyte migrationGO:0097529570.012
microtubule based transportGO:0010970500.012
regulation of tissue remodelingGO:0034103380.012
activation of adenylate cyclase activityGO:000719040.012
cytokine productionGO:00018163190.012
t cell mediated immunityGO:0002456500.012
response to drugGO:0042493750.012
negative regulation of proteolysisGO:0045861740.012
negative regulation of inflammatory responseGO:0050728610.012
positive regulation of defense responseGO:00313491240.012
cellular amide metabolic processGO:0043603580.012
central nervous system neuron differentiationGO:00219531620.012
regulation of cell killingGO:0031341400.012
endocrine processGO:0050886390.012
actin cytoskeleton organizationGO:00300362200.012
digestive tract developmentGO:00485651900.012
hormone secretionGO:00468791280.012
cellular response to dna damage stimulusGO:00069742070.012
organelle transport along microtubuleGO:0072384140.012
ear developmentGO:00435832000.012
sphingolipid catabolic processGO:003014970.012
regulation of cell migrationGO:00303342190.011
regulation of ras protein signal transductionGO:00465781140.011
tissue homeostasisGO:00018941150.011
positive regulation of epithelial cell proliferationGO:0050679680.011
proteolysis involved in cellular protein catabolic processGO:00516031470.011
sensory organ morphogenesisGO:00905962420.011
nucleoside phosphate metabolic processGO:00067533380.011
positive regulation of innate immune responseGO:0045089800.011
positive regulation of cell adhesionGO:0045785800.011
purine ribonucleoside metabolic processGO:00461282410.011
regulation of bone remodelingGO:0046850280.011
regulation of organelle organizationGO:00330432890.011
negative regulation of map kinase activityGO:0043407340.011
granulocyte migrationGO:0097530430.011
synaptic vesicle docking involved in exocytosisGO:001608140.011
negative regulation of cell developmentGO:00107211690.011
cell adhesionGO:00071553290.011
regulation of proteolysisGO:00301621640.011
hatchingGO:003518840.011
positive regulation of cell projection organizationGO:0031346950.011
organonitrogen compound biosynthetic processGO:19015661920.011
epithelial cell migrationGO:0010631630.011
protein oligomerizationGO:0051259670.011
cilium morphogenesisGO:00602711020.011
positive regulation of epithelial cell differentiation involved in kidney developmentGO:200069820.011
response to radiationGO:00093141650.011
dephosphorylationGO:00163111290.011
membrane protein proteolysisGO:0033619100.011
response to reactive oxygen speciesGO:0000302560.011
peptidyl amino acid modificationGO:00181933360.011
erk1 and erk2 cascadeGO:0070371770.011
peptidyl tyrosine phosphorylationGO:00181081430.011
homeostasis of number of cells within a tissueGO:0048873250.011
nucleoside phosphate catabolic processGO:19012922220.011
blastocyst developmentGO:0001824800.011
sequestering of calcium ionGO:0051208180.011
positive regulation of lymphocyte activationGO:00512511400.011
myotube differentiationGO:00149021050.011
regulation of chemotaxisGO:0050920530.011
g1 s transition of mitotic cell cycleGO:0000082570.011
organic hydroxy compound transportGO:0015850930.010
cellular protein complex assemblyGO:00436231160.010
synaptic transmissionGO:00072683290.010
positive regulation of metanephric glomerulus developmentGO:007230040.010
skeletal muscle fiber developmentGO:0048741580.010
monocarboxylic acid metabolic processGO:00327871910.010
myotube cell developmentGO:0014904600.010
regulation of retina development in camera type eyeGO:190286630.010
limb developmentGO:00601731660.010
positive regulation of cell activationGO:00508671580.010
regulation of peptide hormone secretionGO:0090276750.010
hemostasisGO:0007599780.010
intracellular protein transportGO:00068862040.010
regulation of ossificationGO:00302781120.010
lysosomal transportGO:0007041100.010
regulation of tube sizeGO:0035150570.010
organic acid catabolic processGO:0016054510.010
nucleobase containing small molecule metabolic processGO:00550863520.010
bone developmentGO:00603481200.010
innate immune responseGO:00450871570.010

Hexa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.983
Human
sphingolipidosisDOID:192700.983
Human
disease of metabolismDOID:001466700.983
Human
lysosomal storage diseaseDOID:321100.983
Human
lipid storage diseaseDOID:945500.983
Human
disease of anatomical entityDOID:700.773
Human
nervous system diseaseDOID:86300.773
Human
brain diseaseDOID:93600.773
Human
central nervous system diseaseDOID:33100.773
Human
cerebral degenerationDOID:144300.102
Human
immune system diseaseDOID:291400.060
lymphatic system diseaseDOID:7500.060
neuronal ceroid lipofuscinosisDOID:1450300.038
musculoskeletal system diseaseDOID:1700.020
connective tissue diseaseDOID:6500.020
neurodegenerative diseaseDOID:128900.013
retinal diseaseDOID:567900.013
sensory system diseaseDOID:005015500.013
eye and adnexa diseaseDOID:149200.013
eye diseaseDOID:561400.013
primary immunodeficiency diseaseDOID:61200.011