Mus musculus

89 known processes

Helb

helicase (DNA) B

(Aliases: D10Ertd664e,AI447783)

Helb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
apoptotic signaling pathwayGO:00971903060.088
cellular response to dna damage stimulusGO:00069742070.087
regulation of hydrolase activityGO:00513362460.075
cellular macromolecule catabolic processGO:00442652060.074
dna repairGO:00062811070.070
cellular nitrogen compound catabolic processGO:00442702800.065
nucleoside phosphate metabolic processGO:00067533380.063
organic cyclic compound catabolic processGO:19013612950.059
chromatin organizationGO:00063252060.054
cellular amino acid metabolic processGO:00065201030.053
purine nucleotide metabolic processGO:00061633020.051
cellular ketone metabolic processGO:0042180840.050
cation transportGO:00068123990.047
mitotic cell cycleGO:00002781950.047
dna metabolic processGO:00062593030.047
purine nucleoside catabolic processGO:00061522050.045
nucleotide metabolic processGO:00091173320.045
nucleobase containing small molecule metabolic processGO:00550863520.044
macromolecule catabolic processGO:00090572810.044
amine metabolic processGO:0009308450.043
aromatic compound catabolic processGO:00194392860.042
nucleoside triphosphate metabolic processGO:00091412300.041
organonitrogen compound catabolic processGO:19015652640.041
double strand break repairGO:0006302480.041
purine nucleoside metabolic processGO:00422782410.041
protein maturationGO:00516041760.040
purine ribonucleotide metabolic processGO:00091502900.040
mitotic cell cycle processGO:19030471590.040
carbohydrate derivative catabolic processGO:19011362310.039
histone modificationGO:00165701590.039
cellular amine metabolic processGO:0044106440.037
regulation of cell cycle processGO:00105641600.036
heterocycle catabolic processGO:00467002800.036
regulation of cellular ketone metabolic processGO:0010565660.035
purine nucleoside triphosphate metabolic processGO:00091442260.035
positive regulation of hydrolase activityGO:00513451480.035
purine containing compound catabolic processGO:00725232130.034
nucleoside metabolic processGO:00091162460.034
regulation of cellular catabolic processGO:00313292420.034
purine ribonucleoside triphosphate metabolic processGO:00092052200.034
transmembrane transportGO:00550854120.034
negative regulation of cell cycleGO:00457861230.033
immune effector processGO:00022523210.033
protein modification by small protein conjugation or removalGO:00706472070.033
purine nucleotide catabolic processGO:00061952110.033
ribonucleotide metabolic processGO:00092592910.033
microtubule cytoskeleton organizationGO:00002261570.033
negative regulation of protein metabolic processGO:00512482820.033
glycosyl compound metabolic processGO:19016572460.032
regulation of cellular amino acid metabolic processGO:000652150.032
positive regulation of cellular amino acid metabolic processGO:004576430.031
positive regulation of protein modification processGO:00314012990.031
purine containing compound metabolic processGO:00725213110.031
cellular lipid metabolic processGO:00442553230.031
intrinsic apoptotic signaling pathwayGO:00971931320.031
ribose phosphate metabolic processGO:00196932910.031
nucleoside catabolic processGO:00091642060.030
ion transmembrane transportGO:00342203610.030
ras protein signal transductionGO:0007265770.029
organophosphate catabolic processGO:00464342320.029
regulation of cellular response to stressGO:00801351590.029
purine nucleoside triphosphate catabolic processGO:00091462030.029
extrinsic apoptotic signaling pathwayGO:00971911260.029
purine ribonucleotide catabolic processGO:00091542080.029
regulation of transferase activityGO:00513382630.028
innate immune responseGO:00450871570.028
negative regulation of cell proliferationGO:00082852960.028
cation transmembrane transportGO:00986552660.028
regulation of cell cycleGO:00517262810.028
regulation of cellular amine metabolic processGO:0033238200.028
nucleotide catabolic processGO:00091662170.027
response to organonitrogen compoundGO:00102432460.027
chromatin modificationGO:00165681870.027
negative regulation of molecular functionGO:00440922580.027
protein processingGO:00164851630.027
protein modification by small protein conjugationGO:00324461870.027
organic hydroxy compound metabolic processGO:19016152030.027
regulation of endopeptidase activityGO:0052548890.027
regulation of organelle organizationGO:00330432890.027
ribonucleoside triphosphate metabolic processGO:00091992200.027
small gtpase mediated signal transductionGO:0007264970.027
ubiquitin dependent protein catabolic processGO:00065111290.026
regulation of cell activationGO:00508652890.026
protein catabolic processGO:00301632210.026
leukocyte differentiationGO:00025213420.026
oxidation reduction processGO:00551143420.026
nucleoside phosphate catabolic processGO:19012922220.026
ribonucleoside catabolic processGO:00424542060.026
positive regulation of cell deathGO:00109422240.025
regulation of cytokine productionGO:00018172660.025
glycosyl compound catabolic processGO:19016582060.025
ribonucleoside metabolic processGO:00091192450.025
response to radiationGO:00093141650.025
cytoplasmic transportGO:00164822340.024
cellular response to gamma radiationGO:007148040.024
gland developmentGO:00487323300.024
cytokine productionGO:00018163190.024
regulation of kinase activityGO:00435492490.024
ribonucleoside triphosphate catabolic processGO:00092031990.024
regulation of apoptotic signaling pathwayGO:20012331970.024
nucleoside triphosphate catabolic processGO:00091432050.023
protein localization to organelleGO:00333651850.023
modification dependent protein catabolic processGO:00199411330.023
b cell activationGO:00421131610.023
regulation of membrane potentialGO:00423911920.023
response to lipopolysaccharideGO:00324961280.022
cellular protein catabolic processGO:00442571550.022
negative regulation of cellular protein metabolic processGO:00322692470.022
signal transduction involved in dna damage checkpointGO:007242230.022
nitrogen compound transportGO:00717052710.022
purine ribonucleoside triphosphate catabolic processGO:00092071990.022
nuclear divisionGO:00002801580.022
positive regulation of cellular amine metabolic processGO:003324050.022
positive regulation of programmed cell deathGO:00430682180.022
purine ribonucleoside metabolic processGO:00461282410.022
positive regulation of apoptotic processGO:00430652170.021
cellular response to external stimulusGO:0071496880.021
purine ribonucleoside catabolic processGO:00461302050.021
proteolysis involved in cellular protein catabolic processGO:00516031470.021
peptidyl amino acid modificationGO:00181933360.021
negative regulation of phosphate metabolic processGO:00459361840.021
response to extracellular stimulusGO:00099911270.021
organophosphate biosynthetic processGO:00904071220.020
inorganic cation transmembrane transportGO:00986622070.020
negative regulation of cell cycle phase transitionGO:1901988480.020
regulation of peptidase activityGO:0052547960.020
regulation of protein kinase activityGO:00458592320.020
lymphocyte differentiationGO:00300982420.020
positive regulation of cysteine type endopeptidase activityGO:2001056390.020
intracellular protein transportGO:00068862040.020
wnt signaling pathwayGO:00160551880.019
response to molecule of bacterial originGO:00022371430.019
membrane organizationGO:00610242450.019
dna endoreduplicationGO:004202340.019
regulation of secretionGO:00510462740.019
response to nutrient levelsGO:00316671090.019
ribonucleotide catabolic processGO:00092612080.019
microtubule based processGO:00070172360.019
regulation of proteolysisGO:00301621640.019
meiotic cell cycleGO:00513211220.019
regulation of lymphocyte activationGO:00512492400.019
modification dependent macromolecule catabolic processGO:00436321330.018
cellular homeostasisGO:00197252400.018
response to oxidative stressGO:00069791230.018
negative regulation of cell cycle processGO:0010948690.018
positive regulation of protein phosphorylationGO:00019342420.018
nucleoside monophosphate metabolic processGO:0009123850.018
positive regulation of transferase activityGO:00513471670.018
glycerolipid metabolic processGO:00464861220.018
organic anion transportGO:00157111370.018
negative regulation of cellular component organizationGO:00511291940.018
organelle fissionGO:00482851700.018
regulation of multi organism processGO:00439001110.018
protein ubiquitinationGO:00165671710.018
regulation of cysteine type endopeptidase activityGO:2000116650.018
negative regulation of dna replicationGO:000815640.018
positive regulation of cytokine productionGO:00018191740.018
negative regulation of cellular amino acid metabolic processGO:004576300.018
covalent chromatin modificationGO:00165691630.018
cellular response to organonitrogen compoundGO:00714171450.018
endomembrane system organizationGO:00102561470.018
anion transportGO:00068201770.017
inorganic ion transmembrane transportGO:00986602340.017
regulation of protein localizationGO:00328802310.017
mapk cascadeGO:00001652810.017
myeloid cell differentiationGO:00300992330.017
regulation of cell cycle phase transitionGO:1901987770.017
leukocyte mediated immunityGO:00024431740.017
proteasomal protein catabolic processGO:0010498980.017
cell cycle checkpointGO:0000075470.017
negative regulation of mitotic cell cycleGO:0045930580.017
positive regulation of proteolysisGO:0045862850.017
maintenance of locationGO:0051235890.017
carbohydrate derivative biosynthetic processGO:19011371830.017
cellular chemical homeostasisGO:00550822150.017
meiotic nuclear divisionGO:00071261150.016
carbohydrate metabolic processGO:00059752300.016
regulation of mitotic cell cycleGO:00073461260.016
engulfment of apoptotic cellGO:004365230.016
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.016
mitochondrion organizationGO:00070051340.016
lymphocyte proliferationGO:00466511640.016
posttranscriptional regulation of gene expressionGO:00106081550.016
regulation of protein maturationGO:1903317960.016
positive regulation of apoptotic signaling pathwayGO:2001235950.016
regulation of secretion by cellGO:19035302490.016
cell fate commitmentGO:00451652100.016
divalent inorganic cation transportGO:00725111780.016
purine nucleoside monophosphate metabolic processGO:0009126810.016
regulation of establishment of protein localizationGO:00702011810.016
rho protein signal transductionGO:0007266320.016
negative regulation of mitotic cell cycle phase transitionGO:1901991450.016
ossificationGO:00015032160.016
gonad developmentGO:00084061410.016
t cell activationGO:00421102890.016
regulation of defense responseGO:00313472330.016
regulation of chromosome organizationGO:0033044830.016
male gamete generationGO:00482322850.016
urogenital system developmentGO:00016552610.016
purine ribonucleoside monophosphate metabolic processGO:0009167800.016
defense response to virusGO:0051607680.016
regulation of hormone levelsGO:00108172110.016
lipid biosynthetic processGO:00086101790.015
positive regulation of endopeptidase activityGO:0010950430.015
multicellular organism growthGO:00352641610.015
reactive oxygen species metabolic processGO:0072593840.015
negative regulation of organelle organizationGO:0010639900.015
negative regulation of phosphorus metabolic processGO:00105631840.015
regulation of cell divisionGO:0051302760.015
meiotic cell cycle processGO:1903046770.015
organonitrogen compound biosynthetic processGO:19015661920.015
cellular response to abiotic stimulusGO:0071214560.015
nucleic acid phosphodiester bond hydrolysisGO:0090305490.015
blastocyst developmentGO:0001824800.015
endocytosisGO:00068971680.015
multicellular organismal homeostasisGO:00488711640.015
hematopoietic progenitor cell differentiationGO:00022441430.015
b cell differentiationGO:0030183780.015
protein oligomerizationGO:0051259670.015
cellular response to hormone stimulusGO:00328701500.015
cellular response to lipidGO:00713961450.015
dna recombinationGO:0006310920.015
muscle tissue developmentGO:00605373080.015
negative regulation of cellular amine metabolic processGO:003323910.015
interspecies interaction between organismsGO:0044419830.015
response to growth factorGO:00708481980.014
positive regulation of kinase activityGO:00336741550.014
intracellular mrna localizationGO:000829840.014
divalent metal ion transportGO:00708381720.014
protein targetingGO:00066051430.014
regulation of reactive oxygen species metabolic processGO:2000377400.014
circulatory system processGO:00030131970.014
cell type specific apoptotic processGO:00972852680.014
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.014
regulation of mitotic cell cycle phase transitionGO:1901990730.014
response to starvationGO:0042594650.014
nuclear transportGO:00511691390.014
organic acid transportGO:00158491010.014
regulation of protein serine threonine kinase activityGO:00719001570.014
atp metabolic processGO:0046034750.014
kidney developmentGO:00018222130.014
symbiosis encompassing mutualism through parasitismGO:0044403830.014
chromosome segregationGO:0007059480.014
dna dependent dna replication maintenance of fidelityGO:004500530.014
myeloid leukocyte differentiationGO:00025731190.014
neuron deathGO:00709971540.014
activation of cysteine type endopeptidase activityGO:0097202270.014
response to light stimulusGO:00094161350.014
gtp catabolic processGO:00061841430.014
glycerophospholipid metabolic processGO:0006650710.013
protein localization to nucleusGO:00345041210.013
cellular response to extracellular stimulusGO:0031668810.013
ribonucleoside monophosphate metabolic processGO:0009161800.013
negative regulation of protein modification processGO:00314001630.013
leukocyte proliferationGO:00706611720.013
epithelial tube morphogenesisGO:00605623030.013
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.013
positive regulation of peptidase activityGO:0010952490.013
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.013
response to organic cyclic compoundGO:00140701980.013
activation of immune responseGO:00022531380.013
organelle localizationGO:00516401790.013
gtp metabolic processGO:00460391440.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.013
cellular response to cytokine stimulusGO:00713451890.013
respiratory tube developmentGO:00303231670.013
inflammatory responseGO:00069542440.013
response to oxygen levelsGO:0070482620.013
cellular response to growth factor stimulusGO:00713631970.013
sensory perceptionGO:00076002450.013
cellular ion homeostasisGO:00068731650.013
anatomical structure homeostasisGO:00602491450.013
guanosine containing compound catabolic processGO:19010691440.013
cell activation involved in immune responseGO:00022631260.013
small molecule biosynthetic processGO:00442831320.013
establishment of protein localization to organelleGO:00725941180.013
negative regulation of phosphorylationGO:00423261660.013
cellular response to oxidative stressGO:0034599760.013
positive regulation of defense responseGO:00313491240.013
sensory organ morphogenesisGO:00905962420.013
negative regulation of cellular catabolic processGO:0031330470.012
respiratory system developmentGO:00605411900.012
multi multicellular organism processGO:00447061090.012
development of primary sexual characteristicsGO:00451371430.012
blood circulationGO:00080151950.012
regulation of mapk cascadeGO:00434082480.012
muscle cell differentiationGO:00426922610.012
response to acid chemicalGO:00011011110.012
signal transduction involved in mitotic dna damage checkpointGO:190240230.012
positive regulation of mapk cascadeGO:00434101700.012
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.012
cellular response to molecule of bacterial originGO:0071219830.012
alcohol metabolic processGO:00060661160.012
cell cycle g1 s phase transitionGO:0044843570.012
tissue remodelingGO:00487711020.012
purine ribonucleoside monophosphate catabolic processGO:0009169570.012
translationGO:0006412930.012
defense response to other organismGO:00985421970.012
nucleocytoplasmic transportGO:00069131390.012
regulation of innate immune responseGO:0045088910.012
cellular protein complex assemblyGO:00436231160.012
regulation of neuron differentiationGO:00456642810.012
multicellular organismal signalingGO:0035637910.012
spermatogenesisGO:00072832840.012
transmission of nerve impulseGO:0019226760.012
negative regulation of immune system processGO:00026832090.012
leukocyte activation involved in immune responseGO:00023661260.012
blood vessel morphogenesisGO:00485142850.012
response to endoplasmic reticulum stressGO:0034976530.012
signal transduction involved in mitotic dna integrity checkpointGO:190240330.012
response to ionizing radiationGO:0010212420.012
negative regulation of intracellular signal transductionGO:19025321670.012
negative regulation of growthGO:0045926990.012
action potentialGO:0001508780.012
negative regulation of apoptotic signaling pathwayGO:20012341040.012
protein autophosphorylationGO:0046777610.012
lipoprotein metabolic processGO:0042157430.012
retrograde transport endosome to golgiGO:004214720.011
cell divisionGO:00513011200.011
protein secretionGO:00093061110.011
dna replicationGO:0006260520.011
neuron apoptotic processGO:00514021420.011
dephosphorylationGO:00163111290.011
negative regulation of protein processingGO:0010955790.011
positive regulation of secretionGO:00510471300.011
signal transduction in absence of ligandGO:0038034550.011
compound eye developmentGO:004874910.011
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.011
digestive system developmentGO:00551232000.011
lymphocyte mediated immunityGO:00024491390.011
carboxylic acid transportGO:00469421000.011
dna dependent dna replicationGO:0006261240.011
tissue homeostasisGO:00018941150.011
regulation of ion transportGO:00432692150.011
nuclear importGO:0051170950.011
ear developmentGO:00435832000.011
methylationGO:00322591340.011
angiogenesisGO:00015252010.011
anion transmembrane transportGO:0098656710.011
protein import into nucleusGO:0006606950.011
regulation of response to woundingGO:19030341890.011
dna catabolic process endonucleolyticGO:0000737150.011
regulation of interleukin 1 alpha productionGO:003265040.011
phospholipid metabolic processGO:0006644870.011
cellular metal ion homeostasisGO:00068751510.011
atp catabolic processGO:0006200550.011
regulation of interleukin 8 productionGO:003267730.011
protein importGO:00170381010.011
positive regulation of immune effector processGO:00026991070.011
cation homeostasisGO:00550802120.011
negative regulation of phospholipase activityGO:001051940.011
apoptotic mitochondrial changesGO:0008637480.011
cell adhesionGO:00071553290.011
natural killer cell activationGO:0030101440.011
signal transduction involved in cell cycle checkpointGO:007239530.011
skeletal system developmentGO:00015013560.011
regulation of protein processingGO:0070613960.011
carbohydrate homeostasisGO:00335001280.011
telomere cappingGO:001623340.011
g1 s transition of mitotic cell cycleGO:0000082570.010
cellular carbohydrate metabolic processGO:00442621190.010
positive regulation of protein kinase activityGO:00458601440.010
positive regulation of protein serine threonine kinase activityGO:00719021060.010
monocarboxylic acid metabolic processGO:00327871910.010
establishment or maintenance of cytoskeleton polarityGO:003095220.010
renal system developmentGO:00720012250.010
regulation of cellular component biogenesisGO:00440871810.010
mitotic g1 dna damage checkpointGO:003157140.010
protein acylationGO:0043543640.010
alpha amino acid metabolic processGO:1901605590.010
response to uvGO:0009411440.010
lipid localizationGO:00108761260.010
sulfur compound metabolic processGO:00067901000.010
lateral inhibitionGO:004633110.010
positive regulation of organelle organizationGO:00106381280.010
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919270.010
lung developmentGO:00303241640.010
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.010
digestive tract developmentGO:00485651900.010
adaptive immune responseGO:00022501550.010
single organism nuclear importGO:1902593950.010
chromosome organization involved in meiosisGO:0070192390.010
organelle assemblyGO:00709251770.010
cellular response to biotic stimulusGO:0071216920.010

Helb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.029
nervous system diseaseDOID:86300.029
disease of metabolismDOID:001466700.021
hematopoietic system diseaseDOID:7400.015
immune system diseaseDOID:291400.015
cancerDOID:16200.013
organ system cancerDOID:005068600.013
disease of cellular proliferationDOID:1456600.013
sensory system diseaseDOID:005015500.012
inherited metabolic disorderDOID:65500.011
central nervous system diseaseDOID:33100.011
eye diseaseDOID:561400.010
eye and adnexa diseaseDOID:149200.010