IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Haus4

HAUS augmin-like complex, subunit 4

(Aliases: AU016300,D14Ertd500e,9430093H08Rik)

Entrez: 219072
Ensembl: ENSMUSG00000022177
UniProtKB: Q8BFT2

Process Predictions
Disease Predictions

Haus4 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
dna metabolic process	GO:0006259	303	0.710
cellular response to dna damage stimulus	GO:0006974	207	0.252
dna repair	GO:0006281	107	0.201
heterocycle catabolic process	GO:0046700	280	0.171
microtubule based process	GO:0007017	236	0.150
chromosome segregation	GO:0007059	48	0.125
double strand break repair	GO:0006302	48	0.105
cellular nitrogen compound catabolic process	GO:0044270	280	0.103
chromatin organization	GO:0006325	206	0.100
dna recombination	GO:0006310	92	0.092
nuclear division	GO:0000280	158	0.088
double strand break repair via homologous recombination	GO:0000724	21	0.076
mitotic cell cycle	GO:0000278	195	0.074
protein modification by small protein conjugation or removal	GO:0070647	207	0.072
synapsis	GO:0007129	34	0.071
organic cyclic compound catabolic process	GO:1901361	295	0.068
regulation of mitotic cell cycle	GO:0007346	126	0.065
protein ubiquitination	GO:0016567	171	0.065
meiotic cell cycle process	GO:1903046	77	0.063
recombinational repair	GO:0000725	21	0.060
peptidyl amino acid modification	GO:0018193	336	0.060
mitotic cell cycle process	GO:1903047	159	0.059
organonitrogen compound catabolic process	GO:1901565	264	0.058
microtubule based movement	GO:0007018	84	0.056
organelle localization	GO:0051640	179	0.056
purine ribonucleoside catabolic process	GO:0046130	205	0.054
fertilization	GO:0009566	127	0.054
nucleoside catabolic process	GO:0009164	206	0.052
regulation of cell cycle	GO:0051726	281	0.052
meiotic nuclear division	GO:0007126	115	0.050
nucleotide metabolic process	GO:0009117	332	0.049
multicellular organism growth	GO:0035264	161	0.046
establishment of organelle localization	GO:0051656	122	0.043
nucleoside triphosphate metabolic process	GO:0009141	230	0.043
nucleic acid phosphodiester bond hydrolysis	GO:0090305	49	0.043
spermatogenesis	GO:0007283	284	0.042
cellular amino acid metabolic process	GO:0006520	103	0.042
organelle assembly	GO:0070925	177	0.041
ribonucleoside metabolic process	GO:0009119	245	0.041
purine containing compound metabolic process	GO:0072521	311	0.041
germ cell development	GO:0007281	185	0.040
nucleoside triphosphate catabolic process	GO:0009143	205	0.039
purine nucleoside catabolic process	GO:0006152	205	0.039
purine containing compound catabolic process	GO:0072523	213	0.038
aromatic compound catabolic process	GO:0019439	286	0.038
nucleoside phosphate catabolic process	GO:1901292	222	0.038
cellular ketone metabolic process	GO:0042180	84	0.037
lateral inhibition	GO:0046331	1	0.037
purine ribonucleotide metabolic process	GO:0009150	290	0.037
anatomical structure homeostasis	GO:0060249	145	0.036
cellular amine metabolic process	GO:0044106	44	0.036
male gamete generation	GO:0048232	285	0.035
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.035
mitotic cytokinesis	GO:0000281	4	0.035
regulation of cell cycle process	GO:0010564	160	0.034
protein modification by small protein conjugation	GO:0032446	187	0.034
cellular macromolecule catabolic process	GO:0044265	206	0.034
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.034
astral microtubule organization	GO:0030953	3	0.033
chromosome movement towards spindle pole	GO:0051305	3	0.032
negative regulation of cell cycle	GO:0045786	123	0.032
dna replication	GO:0006260	52	0.032
regulation of cellular amino acid metabolic process	GO:0006521	5	0.032
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.031
purine ribonucleoside metabolic process	GO:0046128	241	0.031
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.031
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.031
organelle fission	GO:0048285	170	0.030
microtubule nucleation	GO:0007020	2	0.029
establishment or maintenance of cell polarity	GO:0007163	86	0.029
meiotic cell cycle	GO:0051321	122	0.029
development of primary sexual characteristics	GO:0045137	143	0.028
centrosome duplication	GO:0051298	16	0.028
telomere maintenance	GO:0000723	19	0.028
histone phosphorylation	GO:0016572	9	0.028
apoptotic signaling pathway	GO:0097190	306	0.027
single fertilization	GO:0007338	82	0.027
amine metabolic process	GO:0009308	45	0.027
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.027
regulation of kinase activity	GO:0043549	249	0.027
purine nucleotide catabolic process	GO:0006195	211	0.026
regulation of protein serine threonine kinase activity	GO:0071900	157	0.026
regulation of organelle organization	GO:0033043	289	0.026
regulation of cellular amine metabolic process	GO:0033238	20	0.025
nuclear dna replication	GO:0033260	3	0.025
microtubule organizing center organization	GO:0031023	28	0.025
nucleobase containing small molecule metabolic process	GO:0055086	352	0.025
immune effector process	GO:0002252	321	0.025
cell cycle g2 m phase transition	GO:0044839	20	0.025
positive regulation of cellular catabolic process	GO:0031331	148	0.024
purine nucleoside metabolic process	GO:0042278	241	0.024
leukocyte mediated immunity	GO:0002443	174	0.024
glycosyl compound metabolic process	GO:1901657	246	0.024
lymphocyte differentiation	GO:0030098	242	0.024
organophosphate catabolic process	GO:0046434	232	0.024
positive regulation of cell cycle	GO:0045787	92	0.024
dna dependent dna replication maintenance of fidelity	GO:0045005	3	0.023
positive regulation of cellular amine metabolic process	GO:0033240	5	0.023
regulation of cell cycle phase transition	GO:1901987	77	0.023
regulation of cellular ketone metabolic process	GO:0010565	66	0.023
positive regulation of protein modification process	GO:0031401	299	0.023
mitotic nuclear division	GO:0007067	48	0.023
dephosphorylation	GO:0016311	129	0.023
regulation of mitotic cell cycle phase transition	GO:1901990	73	0.023
lymphocyte mediated immunity	GO:0002449	139	0.022
macromolecule catabolic process	GO:0009057	281	0.022
ubiquitin dependent protein catabolic process	GO:0006511	129	0.022
neural tube development	GO:0021915	160	0.022
mitotic sister chromatid segregation	GO:0000070	14	0.022
microtubule cytoskeleton organization	GO:0000226	157	0.022
endomembrane system organization	GO:0010256	147	0.022
sister chromatid cohesion	GO:0007062	12	0.022
ribonucleotide catabolic process	GO:0009261	208	0.022
negative regulation of mitotic cell cycle	GO:0045930	58	0.021
negative regulation of cellular protein metabolic process	GO:0032269	247	0.021
regulation of lymphocyte proliferation	GO:0050670	117	0.021
maintenance of location	GO:0051235	89	0.021
gland development	GO:0048732	330	0.021
regulation of mitotic sister chromatid segregation	GO:0033047	12	0.021
nucleotide catabolic process	GO:0009166	217	0.021
endocytosis	GO:0006897	168	0.021
female meiosis chromosome segregation	GO:0016321	1	0.021
protein acylation	GO:0043543	64	0.020
t cell activation	GO:0042110	289	0.020
nucleoside phosphate metabolic process	GO:0006753	338	0.020
protein polymerization	GO:0051258	57	0.020
cell aging	GO:0007569	35	0.020
cellular protein complex assembly	GO:0043623	116	0.020
regulation of cell activation	GO:0050865	289	0.020
cation transport	GO:0006812	399	0.020
regulation of response to dna damage stimulus	GO:2001020	34	0.020
hematopoietic stem cell proliferation	GO:0071425	13	0.020
asymmetric stem cell division	GO:0098722	3	0.019
metaphase plate congression	GO:0051310	2	0.019
meiosis i	GO:0007127	60	0.019
protein maturation	GO:0051604	176	0.019
ribonucleotide metabolic process	GO:0009259	291	0.019
protein dna complex subunit organization	GO:0071824	28	0.018
organonitrogen compound biosynthetic process	GO:1901566	192	0.018
regulation of protein localization	GO:0032880	231	0.018
camera type eye development	GO:0043010	266	0.018
cell cycle g1 s phase transition	GO:0044843	57	0.018
regulation of hydrolase activity	GO:0051336	246	0.018
membrane organization	GO:0061024	245	0.018
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.018
peptidyl serine phosphorylation	GO:0018105	74	0.018
adaptive immune response	GO:0002250	155	0.018
ribonucleoside catabolic process	GO:0042454	206	0.017
leukocyte differentiation	GO:0002521	342	0.017
spindle midzone assembly	GO:0051255	1	0.017
regulation of lymphocyte activation	GO:0051249	240	0.017
synaptonemal complex organization	GO:0070193	15	0.017
regulation of protein processing	GO:0070613	96	0.017
regulation of protein maturation	GO:1903317	96	0.017
leukocyte proliferation	GO:0070661	172	0.017
purine nucleotide metabolic process	GO:0006163	302	0.017
modification dependent protein catabolic process	GO:0019941	133	0.016
regulation of protein kinase activity	GO:0045859	232	0.016
regulation of transferase activity	GO:0051338	263	0.016
negative regulation of protein metabolic process	GO:0051248	282	0.016
protein processing	GO:0016485	163	0.016
response to organonitrogen compound	GO:0010243	246	0.016
male meiosis	GO:0007140	37	0.016
positive regulation of protein phosphorylation	GO:0001934	242	0.016
positive regulation of transferase activity	GO:0051347	167	0.016
negative regulation of protein modification process	GO:0031400	163	0.016
dna dependent dna replication	GO:0006261	24	0.016
small gtpase mediated signal transduction	GO:0007264	97	0.016
chromatin modification	GO:0016568	187	0.016
proteasomal protein catabolic process	GO:0010498	98	0.016
cell type specific apoptotic process	GO:0097285	268	0.016
membrane disassembly	GO:0030397	1	0.016
regulation of dna dependent dna replication initiation	GO:0030174	3	0.016
regulation of cellular response to stress	GO:0080135	159	0.016
intracellular protein transport	GO:0006886	204	0.016
ribose phosphate metabolic process	GO:0019693	291	0.016
spindle assembly involved in meiosis	GO:0090306	4	0.016
peptidyl serine modification	GO:0018209	83	0.015
regulation of cellular catabolic process	GO:0031329	242	0.015
metaphase anaphase transition of mitotic cell cycle	GO:0007091	9	0.015
positive regulation of mapk cascade	GO:0043410	170	0.015
mitotic cell cycle checkpoint	GO:0007093	31	0.015
cytokine biosynthetic process	GO:0042089	68	0.015
nucleus localization	GO:0051647	20	0.015
carbohydrate derivative catabolic process	GO:1901136	231	0.015
regulation of cell migration	GO:0030334	219	0.015
glycosyl compound catabolic process	GO:1901658	206	0.015
nucleotide excision repair	GO:0006289	13	0.014
rna processing	GO:0006396	105	0.014
dna damage response signal transduction resulting in transcription	GO:0042772	2	0.014
atp catabolic process	GO:0006200	55	0.014
nucleocytoplasmic transport	GO:0006913	139	0.014
intracellular mrna localization	GO:0008298	4	0.014
ras protein signal transduction	GO:0007265	77	0.014
nucleoside monophosphate catabolic process	GO:0009125	59	0.014
cytokinetic process	GO:0032506	2	0.014
mapk cascade	GO:0000165	281	0.014
ribonucleoside monophosphate metabolic process	GO:0009161	80	0.014
cellular component assembly involved in morphogenesis	GO:0010927	139	0.014
negative regulation of cell proliferation	GO:0008285	296	0.014
positive regulation of protein kinase activity	GO:0045860	144	0.014
negative regulation of cell cycle process	GO:0010948	69	0.014
regulation of cytokine production	GO:0001817	266	0.014
purine ribonucleotide catabolic process	GO:0009154	208	0.014
purine nucleobase biosynthetic process	GO:0009113	3	0.014
regulation of apoptotic signaling pathway	GO:2001233	197	0.014
double strand break repair via nonhomologous end joining	GO:0006303	10	0.014
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	88	0.014
positive regulation of mitotic metaphase anaphase transition	GO:0045842	2	0.014
regulation of nuclear cell cycle dna replication	GO:0033262	2	0.014
negative regulation of mitotic cell cycle phase transition	GO:1901991	45	0.013
spindle assembly involved in female meiosis	GO:0007056	3	0.013
negative regulation of molecular function	GO:0044092	258	0.013
negative regulation of phosphate metabolic process	GO:0045936	184	0.013
reactive oxygen species metabolic process	GO:0072593	84	0.013
cleavage furrow formation	GO:0036089	2	0.013
purine nucleoside monophosphate catabolic process	GO:0009128	58	0.013
skeletal system development	GO:0001501	356	0.013
positive regulation of organelle organization	GO:0010638	128	0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.013
tube closure	GO:0060606	91	0.013
regulation of chromosome organization	GO:0033044	83	0.013
g1 s transition of mitotic cell cycle	GO:0000082	57	0.013
regulation of ubiquitin protein ligase activity involved in mitotic cell cycle	GO:0051439	1	0.013
cell cycle switching mitotic to meiotic cell cycle	GO:0051728	1	0.013
primary neural tube formation	GO:0014020	95	0.013
chromosome separation	GO:0051304	14	0.013
b cell activation	GO:0042113	161	0.013
nuclear envelope organization	GO:0006998	11	0.013
cytokine production	GO:0001816	319	0.013
regulation of microtubule cytoskeleton organization	GO:0070507	37	0.012
cell cycle checkpoint	GO:0000075	47	0.012
regulation of mapk cascade	GO:0043408	248	0.012
negative regulation of phosphorylation	GO:0042326	166	0.012
guanosine containing compound metabolic process	GO:1901068	144	0.012
negative regulation of phosphorus metabolic process	GO:0010563	184	0.012
centrosome cycle	GO:0007098	23	0.012
nucleoside metabolic process	GO:0009116	246	0.012
cell fate commitment	GO:0045165	210	0.012
rna dependent dna replication	GO:0006278	3	0.012
b cell mediated immunity	GO:0019724	71	0.012
regulation of cell projection organization	GO:0031344	206	0.012
regulation of leukocyte proliferation	GO:0070663	121	0.012
mitotic g1 dna damage checkpoint	GO:0031571	4	0.012
spindle assembly	GO:0051225	13	0.012
epithelial tube morphogenesis	GO:0060562	303	0.012
cellular response to cytokine stimulus	GO:0071345	189	0.012
negative regulation of cellular component organization	GO:0051129	194	0.012
peptidyl lysine modification	GO:0018205	77	0.012
positive regulation of mitotic sister chromatid separation	GO:1901970	2	0.012
meiotic cytokinesis	GO:0033206	5	0.012
regulation of g1 s transition of mitotic cell cycle	GO:2000045	35	0.011
dna integrity checkpoint	GO:0031570	28	0.011
regulation of establishment of protein localization	GO:0070201	181	0.011
synaptonemal complex assembly	GO:0007130	13	0.011
nucleoside monophosphate metabolic process	GO:0009123	85	0.011
posttranscriptional regulation of gene expression	GO:0010608	155	0.011
transmembrane transport	GO:0055085	412	0.011
humoral immune response	GO:0006959	57	0.011
positive regulation of kinase activity	GO:0033674	155	0.011
regulation of cell cycle g1 s phase transition	GO:1902806	35	0.011
regulation of cytoskeleton organization	GO:0051493	122	0.011
immunoglobulin mediated immune response	GO:0016064	69	0.011
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.011
positive regulation of chromosome organization	GO:2001252	33	0.011
dna catabolic process exonucleolytic	GO:0000738	3	0.011
dna endoreduplication	GO:0042023	4	0.011
cognition	GO:0050890	149	0.011
leukocyte migration	GO:0050900	124	0.011
fibroblast proliferation	GO:0048144	35	0.011
cytokine metabolic process	GO:0042107	71	0.011
regulation of binding	GO:0051098	111	0.011
regulation of t cell activation	GO:0050863	170	0.011
negative regulation of cell cycle phase transition	GO:1901988	48	0.011
regulation of protein transport	GO:0051223	163	0.011
g2 m transition of mitotic cell cycle	GO:0000086	20	0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	43	0.011
t cell differentiation	GO:0030217	174	0.011
positive regulation of macroautophagy	GO:0016239	3	0.011
gtp metabolic process	GO:0046039	144	0.011
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	40	0.011
cellular response to hormone stimulus	GO:0032870	150	0.011
rna catabolic process	GO:0006401	29	0.011
protein catabolic process	GO:0030163	221	0.011
regulation of cellular component biogenesis	GO:0044087	181	0.011
nuclear import	GO:0051170	95	0.011
cellular lipid metabolic process	GO:0044255	323	0.011
cellular response to organonitrogen compound	GO:0071417	145	0.011
negative regulation of proteolysis	GO:0045861	74	0.010
purine ribonucleoside monophosphate catabolic process	GO:0009169	57	0.010
stress activated protein kinase signaling cascade	GO:0031098	81	0.010
mitotic chromosome condensation	GO:0007076	1	0.010
regulation of cyclin dependent protein serine threonine kinase activity	GO:0000079	16	0.010
response to lipopolysaccharide	GO:0032496	128	0.010
cellular protein catabolic process	GO:0044257	155	0.010
positive regulation of cell activation	GO:0050867	158	0.010
cellular response to insulin stimulus	GO:0032869	78	0.010
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.010
regulation of lymphocyte mediated immunity	GO:0002706	84	0.010
germline cell cycle switching mitotic to meiotic cell cycle	GO:0051729	1	0.010
response to oxidative stress	GO:0006979	123	0.010
nuclear transport	GO:0051169	139	0.010
female gamete generation	GO:0007292	74	0.010
regulation of purine nucleotide metabolic process	GO:1900542	169	0.010
lymphocyte activation involved in immune response	GO:0002285	93	0.010
sister chromatid segregation	GO:0000819	20	0.010
meiotic chromosome segregation	GO:0045132	19	0.010
regulation of intracellular transport	GO:0032386	159	0.010

Haus4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of cellular proliferation	DOID:14566	0.032
cancer	DOID:162	0.032
disease of metabolism	DOID:0014667	0.027
inherited metabolic disorder	DOID:655	0.027
immune system disease	DOID:2914	0.022
disease of anatomical entity	DOID:7	0.022
nervous system disease	DOID:863	0.017
hematopoietic system disease	DOID:74	0.015
central nervous system disease	DOID:331	0.014
bone marrow disease	DOID:4961	0.014
organ system cancer	DOID:0050686	0.012

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