Mus musculus

175 known processes

Smad5

MAD homolog 5 (Drosophila)

(Aliases: MusMLP,AI451355,Madh5,Dwf-C,1110051M15Rik)

Smad5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
skeletal system developmentGO:00015013560.898
bone developmentGO:00603481200.897
stem cell developmentGO:00488642190.813
Mouse Fly
regionalizationGO:00030023370.669
Zebrafish Mouse Fly
skeletal system morphogenesisGO:00487052030.637
Mouse
epithelial tube morphogenesisGO:00605623030.568
Zebrafish Mouse Fly
neural tube developmentGO:00219151600.557
positive regulation of nervous system developmentGO:00519622210.557
Fly
embryonic epithelial tube formationGO:00018381300.506
regulation of cellular ketone metabolic processGO:0010565660.482
embryonic organ morphogenesisGO:00485622760.460
Zebrafish Mouse
t cell activationGO:00421102890.459
Mouse
endocrine system developmentGO:0035270980.458
Mouse
epithelial tube formationGO:00721751300.449
myeloid cell differentiationGO:00300992330.440
cell fate commitmentGO:00451652100.434
digestive system developmentGO:00551232000.420
Zebrafish Mouse Fly
mesenchyme developmentGO:00604851520.417
Mouse
peptidyl lysine modificationGO:0018205770.410
negative regulation of protein metabolic processGO:00512482820.409
Mouse
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.398
Fly
leukocyte differentiationGO:00025213420.393
blood circulationGO:00080151950.387
multicellular organism growthGO:00352641610.381
Worm
negative regulation of necroptotic processGO:006054690.353
proteolysis involved in cellular protein catabolic processGO:00516031470.347
negative regulation of phosphorus metabolic processGO:00105631840.334
Mouse
trunk segmentationGO:003529040.329
Fly
mesoderm developmentGO:00074981000.326
Mouse
neural tube formationGO:00018411080.326
stem cell differentiationGO:00488632680.325
Mouse Fly
embryonic skeletal system developmentGO:00487061200.322
Mouse
peptidyl amino acid modificationGO:00181933360.311
Mouse
protein localization to organelleGO:00333651850.311
Mouse
morphogenesis of embryonic epitheliumGO:00163311590.310
regulation of protein kinase activityGO:00458592320.306
regulation of cellular amino acid metabolic processGO:000652150.303
neural crest cell differentiationGO:0014033540.301
Mouse
cellular amino acid metabolic processGO:00065201030.296
lymphocyte differentiationGO:00300982420.294
mitotic cell cycle processGO:19030471590.293
Fly
regulation of neuron differentiationGO:00456642810.292
cardiac ventricle developmentGO:0003231830.279
Mouse
cellular protein catabolic processGO:00442571550.278
establishment of protein localization to organelleGO:00725941180.275
Mouse
ubiquitin dependent protein catabolic processGO:00065111290.271
positive regulation of neuron differentiationGO:00456661410.261
digestive tract developmentGO:00485651900.254
Zebrafish Mouse Fly
somitogenesisGO:0001756690.252
Mouse
g1 s transition of mitotic cell cycleGO:0000082570.249
Fly
tube formationGO:00351481400.243
dendrite developmentGO:00163581150.241
t cell differentiationGO:00302171740.239
regulation of cellular catabolic processGO:00313292420.234
response to growth factorGO:00708481980.232
homeostasis of number of cellsGO:00488722100.231
germ cell developmentGO:00072811850.224
digestive tract morphogenesisGO:00485461470.223
Zebrafish Mouse Fly
epidermis developmentGO:00085441870.221
Mouse
glial cell apoptotic processGO:003434930.217
modification dependent protein catabolic processGO:00199411330.212
ossificationGO:00015032160.206
cartilage developmentGO:00512161400.206
endocardial cushion formationGO:0003272130.204
Mouse
bmp signaling pathwayGO:0030509930.204
negative regulation of ripoptosome assembly involved in necroptotic processGO:190244330.204
peptide transportGO:00158331330.204
Mouse
negative regulation of cellular amino acid metabolic processGO:004576300.201
cardiac chamber morphogenesisGO:0003206930.196
Mouse
camera type eye developmentGO:00430102660.195
Mouse
regulation of protein serine threonine kinase activityGO:00719001570.193
cell fate commitment involved in formation of primary germ layerGO:0060795260.190
Mouse Fly
covalent chromatin modificationGO:00165691630.190
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.189
Zebrafish Mouse
striated muscle tissue developmentGO:00147062930.188
Mouse
blood vessel morphogenesisGO:00485142850.188
Zebrafish Mouse
formation of primary germ layerGO:0001704770.187
Mouse Fly
segmentationGO:0035282930.187
Mouse Fly
tube closureGO:0060606910.186
negative regulation of phosphorylationGO:00423261660.186
Mouse
regulation of ossificationGO:00302781120.185
connective tissue developmentGO:00614481790.184
ventricular septum morphogenesisGO:0060412270.184
Mouse
cell fate specificationGO:0001708720.184
Fly
cytoplasmic transportGO:00164822340.180
Mouse
positive regulation of protein phosphorylationGO:00019342420.176
Mouse
mitotic cell cycleGO:00002781950.175
Worm Fly
regulation of hormone levelsGO:00108172110.174
Mouse
gastrulationGO:00073691160.173
Zebrafish Mouse Fly
myeloid leukocyte differentiationGO:00025731190.173
protein modification by small protein conjugationGO:00324461870.172
gonad developmentGO:00084061410.171
heart morphogenesisGO:00030071780.170
Zebrafish Mouse
appendage developmentGO:00487361660.169
Fly
primary neural tube formationGO:0014020950.168
regulation of cellular component biogenesisGO:00440871810.168
Fly
regulation of kinase activityGO:00435492490.166
leukocyte proliferationGO:00706611720.165
negative regulation of necrotic cell deathGO:0060547110.164
cardiac ventricle morphogenesisGO:0003208500.164
Mouse
positive regulation of cell developmentGO:00107202370.164
Mouse
mesenchymal cell developmentGO:0014031930.163
Mouse
cardiac chamber developmentGO:00032051080.163
Mouse
regulation of cellular amine metabolic processGO:0033238200.162
negative regulation of protein phosphorylationGO:00019331260.161
Mouse
regulation of protein import into nucleusGO:0042306520.160
Mouse
stress activated protein kinase signaling cascadeGO:0031098810.158
regulation of transferase activityGO:00513382630.155
axon guidanceGO:00074111410.153
Mouse
amide transportGO:00428861380.153
Mouse
regulation of lymphocyte activationGO:00512492400.152
regulation of stem cell proliferationGO:0072091780.151
positive regulation of cellular amine metabolic processGO:003324050.150
stress activated mapk cascadeGO:0051403800.148
eye photoreceptor cell differentiationGO:0001754410.148
germline cell cycle switching mitotic to meiotic cell cycleGO:005172910.147
Worm
cardiac epithelial to mesenchymal transitionGO:0060317180.146
Mouse
embryonic appendage morphogenesisGO:00351131260.145
regulation of stress activated mapk cascadeGO:0032872690.145
morphogenesis of a branching epitheliumGO:00611381930.144
Mouse
pallium developmentGO:00215431200.144
regulation of cellular response to stressGO:00801351590.141
muscle cell differentiationGO:00426922610.140
purine containing compound catabolic processGO:00725232130.139
positive regulation of protein modification processGO:00314012990.139
Mouse
gland developmentGO:00487323300.139
Mouse
negative regulation of apoptotic signaling pathwayGO:20012341040.136
palate developmentGO:0060021760.136
Zebrafish Mouse
cellular amine metabolic processGO:0044106440.136
regulation of cell sizeGO:0008361720.135
stem cell proliferationGO:00720891170.135
single organism nuclear importGO:1902593950.134
Mouse
regulation of apoptotic signaling pathwayGO:20012331970.132
axonogenesisGO:00074092740.132
Mouse
mesenchymal cell differentiationGO:00487621070.132
Mouse
negative regulation of cellular protein metabolic processGO:00322692470.131
Mouse
insulin secretionGO:0030073890.127
Mouse
regulation of cell cycleGO:00517262810.127
Worm Fly
negative regulation of cell proliferationGO:00082852960.125
Mouse
heterocycle catabolic processGO:00467002800.124
regulation of protein transportGO:00512231630.124
Mouse
chromatin modificationGO:00165681870.124
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.124
Mouse
developmental maturationGO:00217001930.123
negative regulation of phosphate metabolic processGO:00459361840.122
Mouse
regulation of myeloid cell differentiationGO:0045637960.122
lens development in camera type eyeGO:0002088620.122
Mouse
positive regulation of growthGO:00459271040.121
Worm Fly
response to organonitrogen compoundGO:00102432460.121
regulation of blood circulationGO:1903522930.120
Mouse
positive regulation of protein kinase activityGO:00458601440.120
embryonic placenta developmentGO:0001892980.119
ribonucleotide catabolic processGO:00092612080.118
transforming growth factor beta receptor signaling pathwayGO:0007179710.116
protein catabolic processGO:00301632210.115
production of molecular mediator of immune responseGO:00024401030.115
intrinsic apoptotic signaling pathwayGO:00971931320.114
cellular ketone metabolic processGO:0042180840.112
apoptotic signaling pathwayGO:00971903060.112
artery developmentGO:0060840530.111
Mouse
b cell activationGO:00421131610.111
regulation of jnk cascadeGO:0046328620.111
purine nucleotide catabolic processGO:00061952110.109
striated muscle contractionGO:0006941450.109
regulation of neuron projection developmentGO:00109751690.109
histone methylationGO:0016571710.108
muscle cell developmentGO:00550011330.108
nuclear importGO:0051170950.107
Mouse
regulation of secretion by cellGO:19035302490.106
male gamete generationGO:00482322850.106
engulfment of apoptotic cellGO:004365230.105
oocyte axis specificationGO:000730920.104
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.103
negative regulation of bmp signaling pathwayGO:0030514350.102
Mouse
regulation of hormone secretionGO:0046883880.102
adaptive immune responseGO:00022501550.101
protein importGO:00170381010.101
Mouse
modification dependent macromolecule catabolic processGO:00436321330.101
cellular response to dna damage stimulusGO:00069742070.099
aromatic compound catabolic processGO:00194392860.098
ventricular septum developmentGO:0003281420.098
Mouse
regulation of synaptic growth at neuromuscular junctionGO:000858240.097
Fly
heart contractionGO:0060047930.096
cellular response to organonitrogen compoundGO:00714171450.095
respiratory system developmentGO:00605411900.095
Mouse
regulation of cell activationGO:00508652890.094
regulation of system processGO:00440572000.094
Mouse
regulation of embryonic developmentGO:0045995710.093
Zebrafish
regulation of leukocyte proliferationGO:00706631210.093
mapk cascadeGO:00001652810.092
Mouse
regulation of epithelial cell proliferationGO:00506781410.092
Mouse
placenta developmentGO:00018901400.092
intracellular protein transportGO:00068862040.090
Mouse
ribose phosphate metabolic processGO:00196932910.090
organonitrogen compound catabolic processGO:19015652640.089
metencephalon developmentGO:0022037890.089
rhythmic processGO:00485111740.088
histone lysine methylationGO:0034968500.088
regulation of leukocyte differentiationGO:19021051590.088
negative regulation of cell developmentGO:00107211690.087
negative regulation of cell fate specificationGO:000999640.087
purine ribonucleoside metabolic processGO:00461282410.087
angiogenesisGO:00015252010.087
glycosyl compound catabolic processGO:19016582060.086
protein ubiquitinationGO:00165671710.086
nucleoside phosphate metabolic processGO:00067533380.086
spermatogenesisGO:00072832840.085
jnk cascadeGO:0007254720.083
synapse organizationGO:00508081250.083
Fly
regulation of b cell activationGO:0050864810.083
lymphocyte proliferationGO:00466511640.083
somatic stem cell maintenanceGO:0035019470.082
Fly
regulation of membrane potentialGO:00423911920.081
cerebellum developmentGO:0021549770.081
cell maturationGO:00484691270.080
cerebellum vasculature morphogenesisGO:006130110.080
response to sterolGO:003631440.079
appendage morphogenesisGO:00351071490.079
Fly
regulation of muscle system processGO:0090257800.079
Mouse
hindbrain developmentGO:00309021280.079
Mouse
peptide secretionGO:00027901140.078
Mouse
positive regulation of cellular amino acid metabolic processGO:004576430.078
development of primary sexual characteristicsGO:00451371430.077
amine metabolic processGO:0009308450.077
cellular response to peptideGO:1901653920.077
heart processGO:0003015940.077
neural crest cell developmentGO:0014032480.077
negative regulation of lymphocyte activationGO:0051250910.077
cellular macromolecule catabolic processGO:00442652060.077
skin developmentGO:00435882200.076
Mouse
anatomical structure homeostasisGO:00602491450.075
cell divisionGO:00513011200.075
Fly
nucleotide catabolic processGO:00091662170.075
neural tube closureGO:0001843900.075
positive regulation of jun kinase activityGO:0043507300.075
glycosyl compound metabolic processGO:19016572460.074
positive regulation of lymphocyte activationGO:00512511400.073
purine ribonucleoside catabolic processGO:00461302050.073
myeloid cell homeostasisGO:00022621140.073
branching morphogenesis of an epithelial tubeGO:00487541590.072
Mouse
gtp catabolic processGO:00061841430.072
regulation of tight junction assemblyGO:200081020.072
endochondral bone morphogenesisGO:0060350500.072
biomineral tissue developmentGO:0031214640.072
organ growthGO:00352651170.071
Mouse
hormone secretionGO:00468791280.071
Mouse
regulation of b cell tolerance inductionGO:000266120.071
oogenesisGO:0048477560.071
Fly
synapse assemblyGO:0007416560.071
Fly
purine containing compound metabolic processGO:00725213110.071
chondrocyte differentiationGO:0002062720.070
Mouse
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.070
pole plasm assemblyGO:000731520.070
positive regulation of cell proliferation involved in heart valve morphogenesisGO:000325110.069
Mouse
regulation of protein maturationGO:1903317960.069
cellular nitrogen compound catabolic processGO:00442702800.069
cellular response to transforming growth factor beta stimulusGO:0071560880.068
positive regulation of apoptotic processGO:00430652170.068
muscle tissue developmentGO:00605373080.068
Mouse
regulation of proteolysisGO:00301621640.068
endodermal cell fate specificationGO:000171440.068
Fly
progesterone secretionGO:004270110.068
negative regulation of cellular component organizationGO:00511291940.067
epithelial cell developmentGO:00020641590.067
Fly
embryonic digit morphogenesisGO:0042733560.067
endoderm developmentGO:0007492450.067
Mouse Fly
embryonic skeletal system morphogenesisGO:0048704910.067
Mouse
canonical wnt signaling pathwayGO:00600701300.067
renal system developmentGO:00720012250.066
urogenital system developmentGO:00016552610.066
regulation of secretionGO:00510462740.066
sensory organ morphogenesisGO:00905962420.066
Zebrafish Fly
muscle system processGO:00030121410.066
regulation of lymphocyte proliferationGO:00506701170.066
protein targetingGO:00066051430.065
Mouse
regulation of cytoplasmic transportGO:19036491120.065
Mouse
regulation of cardiac muscle contractionGO:0055117210.064
Mouse
forebrain developmentGO:00309003020.064
protein acylationGO:0043543640.064
positive regulation of stress activated mapk cascadeGO:0032874480.064
purine ribonucleotide catabolic processGO:00091542080.063
positive regulation of jnk cascadeGO:0046330460.063
negative regulation of protein modification processGO:00314001630.063
Mouse
cardiac muscle tissue morphogenesisGO:0055008440.062
Mouse
b cell differentiationGO:0030183780.062
negative regulation of cell cycle processGO:0010948690.062
Fly
cochlea morphogenesisGO:0090103220.062
peptide hormone secretionGO:00300721090.062
Mouse
response to peptideGO:19016521360.062
cardiac septum morphogenesisGO:0060411460.062
Mouse
nucleoside triphosphate metabolic processGO:00091412300.061
negative regulation of cellular amine metabolic processGO:003323910.061
muscle contractionGO:00069361010.060
maintenance of locationGO:0051235890.060
protein maturationGO:00516041760.059
organic cyclic compound catabolic processGO:19013612950.059
determination of left right symmetryGO:0007368800.059
Zebrafish Mouse
wnt signaling pathwayGO:00160551880.059
purine nucleoside triphosphate metabolic processGO:00091442260.059
developmental growth involved in morphogenesisGO:00605601380.059
bone morphogenesisGO:0060349780.058
morphogenesis of a branching structureGO:00017632030.058
Mouse
purine ribonucleotide metabolic processGO:00091502900.058
nucleoside phosphate catabolic processGO:19012922220.057
regulation of nucleocytoplasmic transportGO:0046822730.057
Mouse
positive regulation of cellular component biogenesisGO:0044089940.057
Fly
purine nucleoside triphosphate catabolic processGO:00091462030.057
nucleobase containing small molecule metabolic processGO:00550863520.057
protein modification by small protein conjugation or removalGO:00706472070.057
purine nucleotide metabolic processGO:00061633020.057
mesoderm formationGO:0001707620.056
Mouse
purine ribonucleoside triphosphate catabolic processGO:00092071990.056
endothelial cell activationGO:004211810.056
Mouse
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.055
somite developmentGO:0061053810.055
Mouse
regulation of establishment of protein localizationGO:00702011810.055
Mouse
regulation of peptide hormone secretionGO:0090276750.055
paraxial mesoderm morphogenesisGO:0048340100.054
Mouse
regulation of organelle organizationGO:00330432890.054
b cell proliferationGO:0042100530.054
neural crest cell migrationGO:0001755320.053
negative regulation of intracellular signal transductionGO:19025321670.053
positive regulation of programmed cell deathGO:00430682180.053
purine nucleoside metabolic processGO:00422782410.053
nucleoside metabolic processGO:00091162460.053
locomotory behaviorGO:00076261950.053
response to acid chemicalGO:00011011110.053
fat cell differentiationGO:00454441600.053
response to insulinGO:00328681000.053
peptidyl tyrosine phosphorylationGO:00181081430.053
positive regulation of map kinase activityGO:0043406840.052
microtubule based processGO:00070172360.052
maternal determination of anterior posterior axis embryoGO:000835820.052
ribonucleoside triphosphate catabolic processGO:00092031990.052
intracellular mrna localizationGO:000829840.052
syncytium formation by plasma membrane fusionGO:0000768420.052
protein methylationGO:0006479810.052
hepaticobiliary system developmentGO:0061008670.051
Mouse
regulation of mapk cascadeGO:00434082480.051
negative regulation of leukocyte proliferationGO:0070664460.051
chromatin organizationGO:00063252060.051
organophosphate catabolic processGO:00464342320.050
retina development in camera type eyeGO:00600411190.050
wound healingGO:00420601570.050
Mouse
positive regulation of osteoblast differentiationGO:0045669340.050
stem cell maintenanceGO:00198271300.050
Fly
branchiomotor neuron axon guidanceGO:002178570.050
response to oxygen levelsGO:0070482620.050
negative regulation of nervous system developmentGO:00519611560.049
immunoglobulin mediated immune responseGO:0016064690.049
establishment or maintenance of cytoskeleton polarityGO:003095220.049
regulation of cell morphogenesis involved in differentiationGO:00107691510.049
Mouse
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.049
negative regulation of cell cycleGO:00457861230.049
Worm Fly
response to molecule of bacterial originGO:00022371430.048
antibacterial peptide biosynthetic processGO:000278020.048
embryonic axis specificationGO:0000578300.048
Mouse
positive regulation of cell deathGO:00109422240.048
nitrogen compound transportGO:00717052710.048
Mouse
regulation of muscle tissue developmentGO:1901861970.048
Mouse
response to transforming growth factor betaGO:0071559880.048
telencephalon developmentGO:00215371860.048
regulation of lymphocyte differentiationGO:00456191070.048
response to uvGO:0009411440.047
labyrinthine layer developmentGO:0060711490.047
mesodermal cell differentiationGO:0048333220.047
Mouse
labyrinthine layer blood vessel developmentGO:0060716210.047
regulation of homeostatic processGO:00328441820.047
regulation of striated muscle cell differentiationGO:0051153810.046
respiratory tube developmentGO:00303231670.046
Mouse
epithelial cell proliferationGO:00506731740.046
Mouse
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902043130.046
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.046
Mouse
cellular response to lipidGO:00713961450.045
negative regulation of endothelial cell differentiationGO:004560220.045
female gamete generationGO:0007292740.045
Fly
circulatory system processGO:00030131970.045
dna metabolic processGO:00062593030.045
cell cycle g1 s phase transitionGO:0044843570.044
Fly
histone modificationGO:00165701590.044
regulation of multi organism processGO:00439001110.044
positive regulation of kinase activityGO:00336741550.044
lateral mesodermal cell differentiationGO:004837130.044
negative regulation of lymphocyte proliferationGO:0050672450.043
cardiocyte differentiationGO:0035051870.043
Mouse
cellular component assembly involved in morphogenesisGO:00109271390.043
response to organic cyclic compoundGO:00140701980.043
ribonucleoside triphosphate metabolic processGO:00091992200.043
ribonucleotide metabolic processGO:00092592910.043
cell differentiation involved in embryonic placenta developmentGO:0060706260.043
limb developmentGO:00601731660.043
negative regulation of osteoblast proliferationGO:003368940.042
Mouse
response to lipopolysaccharideGO:00324961280.042
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.042
negative regulation of b cell activationGO:0050869270.042
epithelial to mesenchymal transitionGO:0001837470.042
Mouse
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361880.042
response to peptide hormoneGO:00434341270.042
response to alcoholGO:0097305480.042
compound eye developmentGO:004874910.042
Fly
kidney developmentGO:00018222130.042
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.042
oocyte constructionGO:000730820.042
lens fiber cell apoptotic processGO:199008640.042
lens morphogenesis in camera type eyeGO:0002089240.042
skeletal muscle cell differentiationGO:0035914660.042
regulation of protein targetingGO:1903533610.041
Mouse
cellular response to growth factor stimulusGO:00713631970.041
establishment or maintenance of cell polarityGO:0007163860.041
proteasomal protein catabolic processGO:0010498980.041
regulation of cytokine productionGO:00018172660.041
regulation of bmp signaling pathwayGO:0030510600.040
Zebrafish Mouse
regulation of peptidyl serine phosphorylationGO:0033135390.040
Mouse
regulation of stem cell differentiationGO:2000736500.040
Mouse
pharyngeal system developmentGO:0060037170.040
positive regulation of b cell activationGO:0050871490.040
pancreas developmentGO:0031016570.040
Mouse
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.040
Mouse
regulation of anatomical structure sizeGO:00900661780.040
regulation of nucleotide catabolic processGO:00308111220.040
hematopoietic progenitor cell differentiationGO:00022441430.039
protein processingGO:00164851630.039
stem cell divisionGO:0017145300.039
Fly
regulation of mitotic cell cycleGO:00073461260.039
Worm Fly
ribonucleoside catabolic processGO:00424542060.039
regulation of adaptive immune responseGO:0002819900.039
cytokine productionGO:00018163190.039
retina vasculature development in camera type eyeGO:0061298170.038
paraxial mesoderm developmentGO:0048339180.038
Mouse
ear morphogenesisGO:00424711180.038
Zebrafish
protein localization to nucleusGO:00345041210.038
Mouse
spermatid differentiationGO:00485151150.038
negative regulation of epithelial cell proliferationGO:0050680640.038
regulation of t cell differentiationGO:0045580830.038
regulation of production of molecular mediator of immune responseGO:0002700650.038
lateral mesoderm morphogenesisGO:004836930.038
hair cycleGO:0042633900.038
Mouse
regulation of axon extensionGO:0030516430.038
regulation of protein catabolic processGO:00421761080.037
regulation of necrotic cell deathGO:0010939130.037
limb morphogenesisGO:00351081490.037
regulation of jun kinase activityGO:0043506400.037
cartilage development involved in endochondral bone morphogenesisGO:0060351240.037
embryonic heart tube morphogenesisGO:0003143510.037
Zebrafish Mouse
spermatid developmentGO:00072861080.037
regulation of intracellular transportGO:00323861590.037
Mouse
regulation of cellular response to growth factor stimulusGO:0090287820.037
Mouse
positive regulation of smad protein import into nucleusGO:006039120.037
Mouse
syncytiotrophoblast cell differentiation involved in labyrinthine layer developmentGO:006071520.037
regulation of bindingGO:00510981110.036
Mouse
syncytium formationGO:0006949430.036
striated muscle cell developmentGO:00550021250.035
regulation of protein localizationGO:00328802310.035
Mouse
positive regulation of cell cycleGO:0045787920.035
Worm
peptidyl serine modificationGO:0018209830.035
Mouse
cellular response to hormone stimulusGO:00328701500.035
liver developmentGO:0001889660.035
Mouse
endoderm formationGO:0001706200.035
Mouse Fly
defecationGO:003042110.035
mesonephric tubule developmentGO:0072164940.035
septum primum developmentGO:000328440.035
alpha beta t cell activationGO:0046631910.035
cellular homeostasisGO:00197252400.035
regulation of purine nucleotide metabolic processGO:19005421690.035
regulation of transforming growth factor beta2 productionGO:003290920.035
cation transmembrane transportGO:00986552660.035
germinal center formationGO:0002467160.035
cerebellum vasculature developmentGO:006130010.035
nucleotide metabolic processGO:00091173320.035
positive regulation of stem cell proliferationGO:2000648590.034
cell cycle switching mitotic to meiotic cell cycleGO:005172810.034
Worm
cell growthGO:00160491300.034
regulation of map kinase activityGO:00434051200.034
oocyte anterior posterior axis specificationGO:000731420.034
embryonic camera type eye developmentGO:0031076360.034
endodermal cell fate commitmentGO:0001711120.034
Fly
positive regulation of striated muscle cell differentiationGO:0051155350.034
embryonic heart tube developmentGO:0035050650.033
Zebrafish Mouse
t cell differentiation in thymusGO:0033077770.033
mesoderm morphogenesisGO:0048332640.033
Mouse
positive regulation of protein serine threonine kinase activityGO:00719021060.033
methylationGO:00322591340.033
lymphocyte activation involved in immune responseGO:0002285930.033
negative regulation of mitotic cell cycleGO:0045930580.033
Worm Fly
female gonad developmentGO:0008585710.033
peptidyl threonine phosphorylationGO:0018107310.033
Mouse
regulation of cell fate commitmentGO:0010453190.033
negative regulation of hormone metabolic processGO:003235140.033
positive regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589920.033
heterochromatin organizationGO:007082840.033
nucleoside catabolic processGO:00091642060.033
lipid localizationGO:00108761260.033
tissue migrationGO:0090130680.033
negative regulation of insulin receptor signaling pathwayGO:0046627140.032

Smad5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.045
cancerDOID:16200.033