Mus musculus

176 known processes

Smad7

MAD homolog 7 (Drosophila)

(Aliases: Madh7)

Smad7 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.984
response to growth factorGO:00708481980.965
cellular response to growth factor stimulusGO:00713631970.965
transforming growth factor beta receptor signaling pathwayGO:0007179710.961
heart morphogenesisGO:00030071780.940
digestive tract developmentGO:00485651900.919
Mouse Fly
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.915
digestive tract morphogenesisGO:00485461470.911
Mouse Fly
negative regulation of cellular response to growth factor stimulusGO:0090288460.908
Human Fly
protein catabolic processGO:00301632210.908
Human
pigment accumulationGO:004347610.903
Worm
proteolysis involved in cellular protein catabolic processGO:00516031470.898
Human
cell fate commitmentGO:00451652100.892
Mouse
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512260.888
Human Fly
cellular response to transforming growth factor beta stimulusGO:0071560880.886
negative regulation of bmp signaling pathwayGO:0030514350.853
bmp signaling pathwayGO:0030509930.851
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.850
Human Mouse Fly
stem cell differentiationGO:00488632680.847
Mouse Fly
negative regulation of protein phosphorylationGO:00019331260.841
negative regulation of peptidyl serine phosphorylationGO:0033137100.835
chondrocyte developmentGO:0002063240.823
negative regulation of osteoblast differentiationGO:0045668300.820
Mouse
homeostasis of number of cellsGO:00488722100.817
Mouse
regulation of bmp signaling pathwayGO:0030510600.804
regulation of neuron projection developmentGO:00109751690.785
formation of primary germ layerGO:0001704770.779
Mouse
ubiquitin dependent protein catabolic processGO:00065111290.778
Human
macromolecule catabolic processGO:00090572810.765
Human
regulation of cell morphogenesis involved in differentiationGO:00107691510.765
Mouse
regulation of chondrocyte differentiationGO:0032330330.757
Mouse
chemotaxisGO:00069352470.755
Mouse Fly
respiratory system developmentGO:00605411900.754
Mouse
fat cell differentiationGO:00454441600.751
negative regulation of cell proliferationGO:00082852960.734
Mouse
stem cell developmentGO:00488642190.734
Mouse Fly
mapk cascadeGO:00001652810.726
Mouse
digestive system developmentGO:00551232000.724
Mouse Fly
negative regulation of cellular amine metabolic processGO:003323910.716
regulation of cellular amine metabolic processGO:0033238200.713
negative regulation of ossificationGO:0030279490.692
Mouse
retinal ganglion cell axon guidanceGO:0031290180.691
Fly
modification dependent macromolecule catabolic processGO:00436321330.689
Human
regulation of cartilage developmentGO:0061035440.685
Mouse
myeloid cell homeostasisGO:00022621140.684
Mouse
stem cell maintenanceGO:00198271300.684
Fly
chondrocyte differentiationGO:0002062720.681
Mouse
positive regulation of apoptotic processGO:00430652170.679
myeloid cell differentiationGO:00300992330.671
Mouse
regulation of cell cycleGO:00517262810.668
negative regulation of cellular protein metabolic processGO:00322692470.663
mesenchyme developmentGO:00604851520.654
Mouse
regulation of ossificationGO:00302781120.646
Mouse
amine metabolic processGO:0009308450.645
negative regulation of phosphorus metabolic processGO:00105631840.643
epithelial tube morphogenesisGO:00605623030.643
Mouse Fly
negative regulation of protein metabolic processGO:00512482820.637
cardiac chamber morphogenesisGO:0003206930.634
wnt signaling pathwayGO:00160551880.631
bone developmentGO:00603481200.624
Mouse
positive regulation of cellular protein catabolic processGO:1903364340.623
Human
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.621
cellular macromolecule catabolic processGO:00442652060.618
Human
muscle cell developmentGO:00550011330.614
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436230.599
Human
ossificationGO:00015032160.591
Mouse
regulation of sequence specific dna binding transcription factor activityGO:00510901060.590
Human
positive regulation of programmed cell deathGO:00430682180.589
forebrain developmentGO:00309003020.587
negative regulation of immune system processGO:00026832090.568
regulation of transferase activityGO:00513382630.559
Human
bone morphogenesisGO:0060349780.558
cellular amino acid metabolic processGO:00065201030.549
germ cell developmentGO:00072811850.546
Mouse
regulation of cellular response to growth factor stimulusGO:0090287820.542
Human Mouse Fly
gastrulationGO:00073691160.530
Mouse
palate developmentGO:0060021760.528
Mouse
positive regulation of stem cell differentiationGO:2000738230.526
Mouse
negative regulation of protein modification processGO:00314001630.525
epidermis developmentGO:00085441870.518
Mouse
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787250.514
regulation of system processGO:00440572000.513
response to transforming growth factor betaGO:0071559880.510
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100430.506
Mouse
endothelial cell differentiationGO:0045446410.504
Mouse
mesoderm developmentGO:00074981000.501
Mouse
regulation of mapk cascadeGO:00434082480.495
synapse organizationGO:00508081250.493
Fly
negative regulation of fat cell differentiationGO:0045599360.484
stem cell proliferationGO:00720891170.482
muscle cell differentiationGO:00426922610.480
respiratory tube developmentGO:00303231670.479
Mouse
stress activated protein kinase signaling cascadeGO:0031098810.477
regulation of cell projection organizationGO:00313442060.477
cellular protein catabolic processGO:00442571550.470
Human
cartilage developmentGO:00512161400.466
Mouse
proteasomal protein catabolic processGO:0010498980.466
Human
regulation of cellular component biogenesisGO:00440871810.458
Fly
regulation of leukocyte differentiationGO:19021051590.456
regulation of cell migrationGO:00303342190.455
somatic stem cell maintenanceGO:0035019470.454
regulation of cellular response to stressGO:00801351590.449
erythrocyte differentiationGO:0030218880.446
Mouse
embryonic organ morphogenesisGO:00485622760.441
Mouse
positive regulation of protein catabolic processGO:0045732600.434
Human
nephrogenic mesenchyme developmentGO:007207630.433
Mouse
endocardial cell differentiationGO:006095640.431
Mouse
developmental growth involved in morphogenesisGO:00605601380.426
Fly
skeletal system morphogenesisGO:00487052030.426
Mouse
endochondral bone morphogenesisGO:0060350500.425
modification dependent protein catabolic processGO:00199411330.424
Human
peptidyl amino acid modificationGO:00181933360.423
regulation of stem cell differentiationGO:2000736500.421
Mouse
smad protein signal transductionGO:0060395210.421
Mouse
regulation of protein kinase activityGO:00458592320.416
regulation of cardiac cell fate specificationGO:200004310.415
jnk cascadeGO:0007254720.414
negative regulation of cellular amino acid metabolic processGO:004576300.414
intracellular protein transportGO:00068862040.414
Mouse
skin developmentGO:00435882200.410
Mouse
axonogenesisGO:00074092740.409
Mouse Fly
epithelial tube formationGO:00721751300.409
heart formationGO:0060914160.408
determination of left right symmetryGO:0007368800.405
Mouse
embryonic epithelial tube formationGO:00018381300.404
positive regulation of protein phosphorylationGO:00019342420.402
Mouse
stress activated mapk cascadeGO:0051403800.398
negative regulation of molecular functionGO:00440922580.397
Human
gonad developmentGO:00084061410.397
myeloid leukocyte differentiationGO:00025731190.394
striated muscle tissue developmentGO:00147062930.393
regulation of myeloid cell differentiationGO:0045637960.391
negative regulation of phosphorylationGO:00423261660.386
regulation of map kinase activityGO:00434051200.385
neuron projection guidanceGO:00974851410.382
Mouse Fly
regulation of jnk cascadeGO:0046328620.380
positive regulation of nervous system developmentGO:00519622210.376
development of primary sexual characteristicsGO:00451371430.373
muscle system processGO:00030121410.372
regulation of neuron differentiationGO:00456642810.363
negative regulation of defense responseGO:0031348770.361
Mouse
blood vessel morphogenesisGO:00485142850.360
skeletal system developmentGO:00015013560.355
Mouse
regulation of stress activated mapk cascadeGO:0032872690.355
renal system developmentGO:00720012250.353
positive regulation of protein serine threonine kinase activityGO:00719021060.347
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.346
Human
negative regulation of phosphate metabolic processGO:00459361840.343
cartilage development involved in endochondral bone morphogenesisGO:0060351240.340
t cell differentiationGO:00302171740.338
cardiac endothelial cell differentiationGO:000334840.337
Mouse
regulation of catenin import into nucleusGO:003541250.333
axon guidanceGO:00074111410.332
Mouse Fly
mesoderm morphogenesisGO:0048332640.331
Mouse
cellular amine metabolic processGO:0044106440.330
cellular response to dna damage stimulusGO:00069742070.329
regulation of fat cell differentiationGO:0045598810.328
positive regulation of cell developmentGO:00107202370.326
Mouse
endothelium developmentGO:0003158450.324
Mouse
negative regulation of inflammatory responseGO:0050728610.322
Mouse
blastocyst developmentGO:0001824800.320
organ growthGO:00352651170.320
Mouse
negative regulation of transferase activityGO:0051348850.315
Human
heart contractionGO:0060047930.314
negative regulation of cell fate specificationGO:000999640.314
regionalizationGO:00030023370.313
Mouse Fly
peptidyl tyrosine phosphorylationGO:00181081430.313
positive regulation of kinase activityGO:00336741550.312
neural tube formationGO:00018411080.311
bone mineralizationGO:0030282540.311
kidney mesenchyme morphogenesisGO:007213140.309
Mouse
wound healingGO:00420601570.306
Mouse
positive regulation of map kinase activityGO:0043406840.304
positive regulation of proteolysisGO:0045862850.301
Human
regulation of osteoblast differentiationGO:0045667670.299
Mouse
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.299
Human
cellular ketone metabolic processGO:0042180840.298
outflow tract morphogenesisGO:0003151530.298
positive regulation of epithelial to mesenchymal transitionGO:0010718130.296
Mouse
positive regulation of protein modification processGO:00314012990.295
Human Mouse
heart field specificationGO:000312860.291
embryonic heart tube morphogenesisGO:0003143510.287
Mouse
cell cell signaling involved in cell fate commitmentGO:0045168350.285
wnt signaling pathway involved in somitogenesisGO:009024440.285
negative regulation of peptidyl threonine phosphorylationGO:001080160.284
regulation of apoptotic signaling pathwayGO:20012331970.281
osteoblast developmentGO:0002076170.278
Mouse
muscle tissue developmentGO:00605373080.277
regulation of kinase activityGO:00435492490.277
regulation of cell fate commitmentGO:0010453190.276
axial mesoderm formationGO:004832030.272
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.270
Mouse
positive regulation of cell proliferation involved in heart valve morphogenesisGO:000325110.270
Mouse
blood circulationGO:00080151950.269
gland developmentGO:00487323300.268
Mouse
connective tissue developmentGO:00614481790.268
Mouse
regulation of synaptic growth at neuromuscular junctionGO:000858240.267
Fly
apoptotic signaling pathwayGO:00971903060.266
nucleocytoplasmic transportGO:00069131390.264
Mouse
protein localization to organelleGO:00333651850.264
Mouse
specification of organ identityGO:0010092300.264
leukocyte differentiationGO:00025213420.263
metanephric mesenchyme morphogenesisGO:007213340.261
Mouse
cell fate specificationGO:0001708720.258
regulation of lymphocyte activationGO:00512492400.257
camera type eye developmentGO:00430102660.255
Mouse
cardiac muscle tissue developmentGO:00487381300.253
regulation of intracellular transportGO:00323861590.253
Mouse
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.252
Human
sensory organ morphogenesisGO:00905962420.252
cation transportGO:00068123990.252
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulusGO:190152270.251
Mouse
negative regulation of osteoblast proliferationGO:003368940.250
Mouse
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.247
Human
biomineral tissue developmentGO:0031214640.247
positive regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:200006080.246
mesenchymal cell proliferationGO:0010463440.245
regulation of cell motilityGO:20001452360.240
positive regulation of cell deathGO:00109422240.238
negative regulation of cell developmentGO:00107211690.238
sensory perception of soundGO:0007605970.237
regulation of cellular catabolic processGO:00313292420.236
Human
negative regulation of neuron differentiationGO:00456651010.233
kidney developmentGO:00018222130.232
regulation of cellular protein catabolic processGO:1903362610.231
Human
regulation of blood circulationGO:1903522930.230
striated muscle cell developmentGO:00550021250.227
mesoderm formationGO:0001707620.225
Mouse
tube formationGO:00351481400.223
regulation of bindingGO:00510981110.222
Mouse
pallium developmentGO:00215431200.220
negative regulation of growthGO:0045926990.220
Fly
sensory perception of mechanical stimulusGO:00509541070.219
positive regulation of transferase activityGO:00513471670.214
regulation of angiogenesisGO:0045765810.214
regulation of jun kinase activityGO:0043506400.212
inflammatory responseGO:00069542440.212
Mouse
leukocyte proliferationGO:00706611720.211
forebrain cell migrationGO:0021885580.209
developmental maturationGO:00217001930.205
positive regulation of cell projection organizationGO:0031346950.202
morphogenesis of embryonic epitheliumGO:00163311590.202
ubiquitin dependent smad protein catabolic processGO:003057920.201
hindbrain developmentGO:00309021280.201
Mouse
regulation of organ morphogenesisGO:20000271440.201
Mouse
embryonic heart tube developmentGO:0035050650.199
Mouse
regulation of cellular ketone metabolic processGO:0010565660.199
regulation of cardioblast differentiationGO:005189030.199
regulation of ion transportGO:00432692150.198
peptidyl threonine phosphorylationGO:0018107310.197
regulation of cellular amino acid metabolic processGO:000652150.197
negative regulation of dna templated transcription elongationGO:003278560.196
regulation of establishment of protein localizationGO:00702011810.196
Mouse
cell proliferation involved in heart valve developmentGO:200079320.195
Mouse
single organism cell adhesionGO:00986021560.194
cell adhesionGO:00071553290.193
nephrogenic mesenchyme morphogenesisGO:007213420.192
Mouse
myotube differentiationGO:00149021050.192
regulation of blood pressureGO:0008217930.191
regulation of muscle contractionGO:0006937490.191
regulation of cell fate specificationGO:0042659100.188
epithelial cell developmentGO:00020641590.187
rhythmic processGO:00485111740.184
extrinsic apoptotic signaling pathwayGO:00971911260.183
activin receptor signaling pathwayGO:0032924180.182
Human
positive regulation of protein kinase activityGO:00458601440.180
circulatory system processGO:00030131970.180
cellular protein complex assemblyGO:00436231160.179
regulation of nucleocytoplasmic transportGO:0046822730.178
Mouse
positive regulation of ubiquitin protein transferase activityGO:005144340.178
metanephros developmentGO:0001656790.178
Mouse
morphogenesis of a branching structureGO:00017632030.176
Mouse
regulation of protein catabolic processGO:00421761080.176
Human
positive regulation of protein ubiquitinationGO:0031398270.175
Human
telencephalon developmentGO:00215371860.174
positive regulation of cell migrationGO:00303351090.174
dna metabolic processGO:00062593030.174
ventricular septum developmentGO:0003281420.172
regulation of secretionGO:00510462740.171
smad protein complex assemblyGO:000718310.170
positive regulation of cellular catabolic processGO:00313311480.170
Human
lens development in camera type eyeGO:0002088620.170
Mouse
negative regulation of myeloid cell differentiationGO:0045638380.169
positive regulation of neuron differentiationGO:00456661410.169
positive regulation of mapk cascadeGO:00434101700.168
regulation of muscle tissue developmentGO:1901861970.167
Mouse
alpha beta t cell activationGO:0046631910.167
central nervous system neuron differentiationGO:00219531620.166
neural tube developmentGO:00219151600.166
cardiocyte differentiationGO:0035051870.165
Mouse
negative regulation of pathway restricted smad protein phosphorylationGO:006039410.164
Human
positive regulation of jun kinase activityGO:0043507300.164
appendage developmentGO:00487361660.162
Fly
pathway restricted smad protein phosphorylationGO:0060389100.160
peptidyl threonine modificationGO:0018210310.160
multicellular organism growthGO:00352641610.160
mitotic cell cycleGO:00002781950.159
protein importGO:00170381010.159
Mouse
negative regulation of nervous system developmentGO:00519611560.159
Fly
cardiac cell fate specificationGO:006091220.158
protein import into nucleusGO:0006606950.158
Mouse
cell proliferation involved in heart valve morphogenesisGO:000324910.158
Mouse
endocardial cushion morphogenesisGO:0003203180.158
Mouse
lateral inhibitionGO:004633110.158
embryonic skeletal system morphogenesisGO:0048704910.157
Mouse
mitotic cell cycle processGO:19030471590.157
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.157
regulation of protein serine threonine kinase activityGO:00719001570.156
embryonic limb morphogenesisGO:00303261260.155
mammary gland morphogenesisGO:0060443540.155
regulation of protein transportGO:00512231630.153
Mouse
heart growthGO:0060419450.153
Mouse
regulation of muscle system processGO:0090257800.151
response to organonitrogen compoundGO:00102432460.151
epithelial to mesenchymal transitionGO:0001837470.151
Mouse
regulation of heart contractionGO:0008016770.150
skeletal muscle fiber developmentGO:0048741580.150
ras protein signal transductionGO:0007265770.149
regulation of epithelial cell proliferationGO:00506781410.148
Mouse
regulation of epithelial to mesenchymal transitionGO:0010717220.148
Mouse
positive regulation of dna templated transcription elongationGO:003278620.148
actin filament organizationGO:00070151130.148
regulation of lymphocyte anergyGO:000291140.147
cardiac ventricle developmentGO:0003231830.147
cell recognitionGO:0008037830.147
morphogenesis of a branching epitheliumGO:00611381930.147
Mouse
cell cell junction organizationGO:0045216720.146
Human
anatomical structure homeostasisGO:00602491450.146
canonical wnt signaling pathwayGO:00600701300.145
protein targetingGO:00066051430.145
Mouse
ear morphogenesisGO:00424711180.145
developmental cell growthGO:0048588840.144
regulation of ligase activityGO:0051340100.144
Human
t cell activationGO:00421102890.143
Mouse
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.143
Human
positive regulation of t cell anergyGO:000266940.143
cell growthGO:00160491300.142
Fly
positive regulation of apoptotic signaling pathwayGO:2001235950.142
metencephalon developmentGO:0022037890.142
regulation of organelle organizationGO:00330432890.141
angiogenesisGO:00015252010.139
regulation of hormone secretionGO:0046883880.138
covalent chromatin modificationGO:00165691630.138
positive regulation of stress activated mapk cascadeGO:0032874480.138
embryonic skeletal system developmentGO:00487061200.136
Mouse
regulation of erk1 and erk2 cascadeGO:0070372710.135
regulation of chromosome organizationGO:0033044830.134
nuclear importGO:0051170950.134
Mouse
cardiac chamber developmentGO:00032051080.133
establishment of protein localization to organelleGO:00725941180.131
Mouse
cell fate commitment involved in formation of primary germ layerGO:0060795260.131
Mouse
regulation of myeloid leukocyte differentiationGO:0002761580.131
endocrine system developmentGO:0035270980.131
Mouse
female gamete generationGO:0007292740.129
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.129
regulation of membrane potentialGO:00423911920.128
regulation of endothelial cell differentiationGO:0045601100.128
epithelial cell migrationGO:0010631630.127
macromolecule deacylationGO:0098732370.127
muscle fiber developmentGO:0048747760.126
hepaticobiliary system developmentGO:0061008670.125
Mouse
cerebral cortex cell migrationGO:0021795440.124
cardiac septum developmentGO:0003279590.123
protein modification by small protein conjugation or removalGO:00706472070.123
Human
somite developmentGO:0061053810.123
Mouse
regulation of t cell anergyGO:000266740.123
response to fluid shear stressGO:003440570.123
Human
single organismal cell cell adhesionGO:00163371310.122
regulation of neural precursor cell proliferationGO:2000177700.122
neuron migrationGO:00017641220.121
positive regulation of epithelial cell proliferationGO:0050679680.120
lymphocyte proliferationGO:00466511640.120
regulation of mesenchymal cell proliferationGO:0010464370.120
inner ear morphogenesisGO:00424721010.119
regulation of canonical wnt signaling pathwayGO:0060828820.118
endocytosisGO:00068971680.118
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902043130.117
positive regulation of cell motilityGO:20001471160.117
cardiac muscle tissue morphogenesisGO:0055008440.116
protein localization to nucleusGO:00345041210.116
Mouse
organelle localizationGO:00516401790.116
regulation of stem cell proliferationGO:0072091780.116
positive regulation of jnk cascadeGO:0046330460.115
cell agingGO:0007569350.115
neural precursor cell proliferationGO:00613511210.114
response to radiationGO:00093141650.114
secondary heart field specificationGO:000313960.114
regulation of alpha beta t cell activationGO:0046634530.113
development of primary female sexual characteristicsGO:0046545730.113
positive regulation of lymphocyte anergyGO:000291340.112
endodermal cell fate commitmentGO:0001711120.111
regulation of protein targetingGO:1903533610.111
Mouse
ameboidal type cell migrationGO:00016671280.111
positive regulation of transforming growth factor beta receptor signaling pathwayGO:0030511120.110
genetic imprintingGO:0071514270.110
regulation of cell projection assemblyGO:0060491380.110
skeletal muscle organ developmentGO:00605381630.110
renal tubule developmentGO:0061326870.109
Mouse Fly
endodermal cell fate specificationGO:000171440.109
protein modification by small protein conjugationGO:00324461870.108
Human
regulation of cell cycle processGO:00105641600.108
cytoplasmic microtubule organizationGO:0031122140.108
muscle contractionGO:00069361010.107
positive regulation of cellular amino acid metabolic processGO:004576430.106
hormone secretionGO:00468791280.106
Mouse
extracellular matrix organizationGO:00301981470.105
peptidyl serine modificationGO:0018209830.105
rho protein signal transductionGO:0007266320.104
negative regulation of systemic arterial blood pressureGO:0003085150.104
cardiac muscle contractionGO:0060048320.104
synapse assemblyGO:0007416560.103
Fly
negative regulation of cell activationGO:00508661110.103
cell junction assemblyGO:0034329520.103
Human
regulation of wnt signaling pathwayGO:00301111230.103
regulation of proteolysisGO:00301621640.103
Human
regulation of ion transmembrane transportGO:00347651190.103
synaptic transmissionGO:00072683290.102
Fly
tissue homeostasisGO:00018941150.101
cerebral cortex developmentGO:0021987860.101
female sex differentiationGO:0046660840.100
synaptic growth at neuromuscular junctionGO:005112460.100
Fly
regulation of cell growthGO:0001558910.100
positive regulation of cellular amine metabolic processGO:003324050.100
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:2000058140.100
neuroepithelial cell differentiationGO:0060563370.100
genitalia developmentGO:0048806370.100
chromatin organizationGO:00063252060.099
cell divisionGO:00513011200.099
mesendoderm developmentGO:004838230.098
t cell anergyGO:000287040.098
odontogenesisGO:0042476780.097
peptide transportGO:00158331330.096
Mouse
mammary gland epithelium developmentGO:0061180650.096
positive regulation of leukocyte differentiationGO:1902107860.096
epithelial to mesenchymal transition involved in endocardial cushion formationGO:0003198100.096
Mouse
protein autophosphorylationGO:0046777610.096
multi multicellular organism processGO:00447061090.096
Worm
multi organism behaviorGO:0051705620.095
Worm
regulation of hormone levelsGO:00108172110.095
Mouse
single organism nuclear importGO:1902593950.094
Mouse
sensory perceptionGO:00076002450.094
positive regulation of stem cell proliferationGO:2000648590.094
microtubule based processGO:00070172360.093
auditory receptor cell differentiationGO:0042491370.093
negative regulation of response to woundingGO:1903035770.092
Mouse
negative regulation of intracellular signal transductionGO:19025321670.092
germ line stem cell divisionGO:004207820.091
endocardial cushion developmentGO:0003197260.091
Mouse
regulation of protein import into nucleusGO:0042306520.091
Mouse
amide transportGO:00428861380.091
Mouse
histone modificationGO:00165701590.089
regulation of protein modification by small protein conjugation or removalGO:1903320570.089
Human
adaptive immune responseGO:00022501550.089
regulation of lymphocyte differentiationGO:00456191070.089
endocardium developmentGO:0003157100.089
Mouse
embryonic placenta developmentGO:0001892980.089
embryonic skeletal joint developmentGO:0072498130.089
regulation of lymphocyte proliferationGO:00506701170.088
nuclear transportGO:00511691390.088
Mouse
blastocyst formationGO:0001825330.088
positive regulation of bmp signaling pathwayGO:0030513230.088
neural tube closureGO:0001843900.088
ion transmembrane transportGO:00342203610.088
regulation of wound healingGO:0061041400.086
Mouse
negative regulation of protein serine threonine kinase activityGO:0071901490.086
cardiac septum morphogenesisGO:0060411460.085
cell fate determinationGO:0001709320.085
t cell proliferationGO:00420981200.085
adult behaviorGO:00305341350.084
regulation of striated muscle cell differentiationGO:0051153810.084
multicellular organismal reproductive behaviorGO:0033057230.084
Worm
regulation of embryonic developmentGO:0045995710.084
paraxial mesoderm morphogenesisGO:0048340100.084
Mouse
skeletal muscle cell differentiationGO:0035914660.084
segmentationGO:0035282930.084
Mouse
lymphocyte anergyGO:000224940.084
regulation of smad protein import into nucleusGO:006039030.084
Mouse
regulation of proteasomal protein catabolic processGO:0061136460.084
Human
somitogenesisGO:0001756690.083
Mouse
regulation of inflammatory responseGO:00507271470.083
Mouse
brainstem developmentGO:000336030.083
Mouse
placenta developmentGO:00018901400.083
heart valve morphogenesisGO:0003179210.083
Mouse
regulation of ubiquitin protein transferase activityGO:005143870.082
Human
response to oxidative stressGO:00069791230.082
tube closureGO:0060606910.082
regulation of intracellular protein transportGO:0033157820.082
Mouse
dendritic cell differentiationGO:0097028260.082
cellular response to extracellular stimulusGO:0031668810.082

Smad7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.818
Human
cancerDOID:16200.279
Human
organ system cancerDOID:005068600.279
Human
heart diseaseDOID:11400.269
disease of anatomical entityDOID:700.269
cardiovascular system diseaseDOID:128700.269
gastrointestinal system cancerDOID:311900.099
Human
musculoskeletal system diseaseDOID:1700.092
connective tissue diseaseDOID:6500.092