IMP: Integrative Multi-species Prediction

Mus musculus

80 known processes

Arnt2

aryl hydrocarbon receptor nuclear translocator 2

(Aliases: Hif-2b,mKIAA0307,bHLHe1)

Entrez: 11864
Ensembl: ENSMUSG00000015709
UniProtKB: Q61324

Process Predictions
Disease Predictions

Arnt2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
angiogenesis	GO:0001525	201	0.706
regulation of hormone levels	GO:0010817	211	0.601	Mouse
peptide transport	GO:0015833	133	0.512	Mouse
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.512
cellular chemical homeostasis	GO:0055082	215	0.502
forebrain development	GO:0030900	302	0.483	Zebrafish
muscle cell differentiation	GO:0042692	261	0.446
cellular response to growth factor stimulus	GO:0071363	197	0.446
limbic system development	GO:0021761	72	0.435	Zebrafish
skeletal system development	GO:0001501	356	0.435
carbohydrate homeostasis	GO:0033500	128	0.421
cation transport	GO:0006812	399	0.413
regulation of cell migration	GO:0030334	219	0.400
positive regulation of cell development	GO:0010720	237	0.398
nitrogen compound transport	GO:0071705	271	0.391	Mouse
cytoplasmic transport	GO:0016482	234	0.389	Mouse
positive regulation of nervous system development	GO:0051962	221	0.371
embryonic organ morphogenesis	GO:0048562	276	0.357
developmental maturation	GO:0021700	193	0.350	Zebrafish
mesenchymal cell differentiation	GO:0048762	107	0.346
chemotaxis	GO:0006935	247	0.329	Zebrafish
cellular amine metabolic process	GO:0044106	44	0.323
regulation of neuron differentiation	GO:0045664	281	0.322	Fly
regulation of homeostatic process	GO:0032844	182	0.319
cellular ion homeostasis	GO:0006873	165	0.308
metal ion homeostasis	GO:0055065	189	0.305
adult locomotory behavior	GO:0008344	91	0.296
cellular metal ion homeostasis	GO:0006875	151	0.295
regulation of body fluid levels	GO:0050878	162	0.292
telencephalon development	GO:0021537	186	0.292
intracellular protein transport	GO:0006886	204	0.282	Mouse
regulation of cellular ketone metabolic process	GO:0010565	66	0.279
amide transport	GO:0042886	138	0.275	Mouse
cellular homeostasis	GO:0019725	240	0.274
amine metabolic process	GO:0009308	45	0.273
regulation of extent of cell growth	GO:0061387	52	0.265
regulation of peptide transport	GO:0090087	91	0.261	Mouse
calcium ion homeostasis	GO:0055074	127	0.260
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.260
cellular amino acid metabolic process	GO:0006520	103	0.260
appendage development	GO:0048736	166	0.258
purine containing compound metabolic process	GO:0072521	311	0.257
forebrain neuron differentiation	GO:0021879	52	0.256
positive regulation of cellular amine metabolic process	GO:0033240	5	0.256
kidney development	GO:0001822	213	0.255
neuron projection guidance	GO:0097485	141	0.255	Zebrafish
smoothened signaling pathway	GO:0007224	105	0.254
stem cell differentiation	GO:0048863	268	0.248
neural crest cell migration	GO:0001755	32	0.248
negative regulation of nervous system development	GO:0051961	156	0.248
carbohydrate metabolic process	GO:0005975	230	0.245
regulation of anatomical structure size	GO:0090066	178	0.241
regulation of vasculature development	GO:1901342	88	0.241
cation homeostasis	GO:0055080	212	0.238
synaptic transmission	GO:0007268	329	0.237
diencephalon development	GO:0021536	63	0.226	Zebrafish
transmembrane transport	GO:0055085	412	0.225
locomotory behavior	GO:0007626	195	0.225
digestive tract development	GO:0048565	190	0.224
lymphocyte differentiation	GO:0030098	242	0.223
embryonic epithelial tube formation	GO:0001838	130	0.222
central nervous system neuron differentiation	GO:0021953	162	0.221
neural precursor cell proliferation	GO:0061351	121	0.220
pallium development	GO:0021543	120	0.220
developmental growth involved in morphogenesis	GO:0060560	138	0.219
blood circulation	GO:0008015	195	0.219
adult walking behavior	GO:0007628	41	0.217
leukocyte differentiation	GO:0002521	342	0.216
neuron projection extension	GO:1990138	64	0.215
regionalization	GO:0003002	337	0.213
regulation of nucleotide metabolic process	GO:0006140	169	0.212
epithelial tube formation	GO:0072175	130	0.212
regulation of protein transport	GO:0051223	163	0.212
regulation of protein localization	GO:0032880	231	0.211
divalent inorganic cation homeostasis	GO:0072507	138	0.205
regulation of cellular amino acid metabolic process	GO:0006521	5	0.203
organophosphate biosynthetic process	GO:0090407	122	0.203
developmental cell growth	GO:0048588	84	0.201
insulin secretion	GO:0030073	89	0.200	Mouse
response to growth factor	GO:0070848	198	0.195
g protein coupled receptor signaling pathway	GO:0007186	243	0.193
regulation of secretion	GO:0051046	274	0.191	Mouse
respiratory tube development	GO:0030323	167	0.190
mesonephros development	GO:0001823	97	0.189
regulation of cellular amine metabolic process	GO:0033238	20	0.188
glycoprotein metabolic process	GO:0009100	116	0.186
purine nucleotide metabolic process	GO:0006163	302	0.185
negative regulation of growth	GO:0045926	99	0.182
forebrain cell migration	GO:0021885	58	0.176
regulation of angiogenesis	GO:0045765	81	0.175
primary neural tube formation	GO:0014020	95	0.174
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.174
neuroblast proliferation	GO:0007405	49	0.173
regulation of cellular catabolic process	GO:0031329	242	0.173
nucleoside phosphate metabolic process	GO:0006753	338	0.167
purine nucleoside metabolic process	GO:0042278	241	0.166
negative regulation of cell development	GO:0010721	169	0.163
positive regulation of secretion	GO:0051047	130	0.163
negative regulation of cell proliferation	GO:0008285	296	0.163
carbohydrate derivative biosynthetic process	GO:1901137	183	0.162
regulation of neuron death	GO:1901214	134	0.162
neuromuscular process	GO:0050905	99	0.161
learning	GO:0007612	98	0.160
regulation of cell motility	GO:2000145	236	0.159
forebrain generation of neurons	GO:0021872	63	0.159
tube formation	GO:0035148	140	0.158
neural tube development	GO:0021915	160	0.157
regulation of cellular response to growth factor stimulus	GO:0090287	82	0.157
striated muscle tissue development	GO:0014706	293	0.157	Mouse
axonogenesis	GO:0007409	274	0.156	Zebrafish
t cell activation	GO:0042110	289	0.155
cerebellum development	GO:0021549	77	0.155
endomembrane system organization	GO:0010256	147	0.155
protein localization to membrane	GO:0072657	108	0.153
ribonucleoside metabolic process	GO:0009119	245	0.152
positive regulation of protein phosphorylation	GO:0001934	242	0.152
ameboidal type cell migration	GO:0001667	128	0.150
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.149
regulation of neuron projection development	GO:0010975	169	0.147
protein localization to nucleus	GO:0034504	121	0.146	Mouse
peptidyl amino acid modification	GO:0018193	336	0.145
axon guidance	GO:0007411	141	0.145	Zebrafish
cerebral cortex development	GO:0021987	86	0.144
regulation of mapk cascade	GO:0043408	248	0.143
ribonucleotide metabolic process	GO:0009259	291	0.143
carbohydrate transport	GO:0008643	62	0.141
nucleobase containing small molecule metabolic process	GO:0055086	352	0.141
purine nucleotide catabolic process	GO:0006195	211	0.139
regulation of secretion by cell	GO:1903530	249	0.139	Mouse
mapk cascade	GO:0000165	281	0.139
positive regulation of cell migration	GO:0030335	109	0.139
multicellular organismal homeostasis	GO:0048871	164	0.138
cellular carbohydrate metabolic process	GO:0044262	119	0.138
morphogenesis of embryonic epithelium	GO:0016331	159	0.138
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.138
regulation of hormone secretion	GO:0046883	88	0.138	Mouse
hormone secretion	GO:0046879	128	0.137	Mouse
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.137
mesenchyme development	GO:0060485	152	0.137
regulation of organ morphogenesis	GO:2000027	144	0.135	Fly
purine ribonucleotide metabolic process	GO:0009150	290	0.134
nucleotide metabolic process	GO:0009117	332	0.134
regulation of peptide secretion	GO:0002791	77	0.134	Mouse
embryonic digit morphogenesis	GO:0042733	56	0.134
ion transmembrane transport	GO:0034220	361	0.132
ear morphogenesis	GO:0042471	118	0.131
neural crest cell development	GO:0014032	48	0.131
regulation of heart contraction	GO:0008016	77	0.131
second messenger mediated signaling	GO:0019932	73	0.130
apoptotic signaling pathway	GO:0097190	306	0.129
regulation of axon extension	GO:0030516	43	0.128
neuron death	GO:0070997	154	0.128
telencephalon cell migration	GO:0022029	55	0.128
bone development	GO:0060348	120	0.127
canonical wnt signaling pathway	GO:0060070	130	0.125	Mouse
connective tissue development	GO:0061448	179	0.125
muscle tissue development	GO:0060537	308	0.125	Mouse
adult behavior	GO:0030534	135	0.125
regulation of system process	GO:0044057	200	0.125
positive regulation of secretion by cell	GO:1903532	114	0.124
cellular nitrogen compound catabolic process	GO:0044270	280	0.123
regulation of transferase activity	GO:0051338	263	0.122
regulation of cell projection organization	GO:0031344	206	0.122
regulation of ion transport	GO:0043269	215	0.122
glucose homeostasis	GO:0042593	128	0.121
regulation of blood circulation	GO:1903522	93	0.120
regulation of hydrolase activity	GO:0051336	246	0.118
digestive system development	GO:0055123	200	0.118
cell growth	GO:0016049	130	0.117
regulation of cell growth	GO:0001558	91	0.116
skeletal system morphogenesis	GO:0048705	203	0.115
inorganic ion transmembrane transport	GO:0098660	234	0.115
cell adhesion	GO:0007155	329	0.113	Zebrafish
regulation of ras gtpase activity	GO:0032318	88	0.113
response to transforming growth factor beta	GO:0071559	88	0.112
body fluid secretion	GO:0007589	53	0.110
purine ribonucleoside metabolic process	GO:0046128	241	0.110
cyclic purine nucleotide metabolic process	GO:0052652	43	0.110
negative regulation of molecular function	GO:0044092	258	0.108
pituitary gland development	GO:0021983	38	0.106
ribonucleotide catabolic process	GO:0009261	208	0.106
positive regulation of synaptic growth at neuromuscular junction	GO:0045887	1	0.106
organophosphate catabolic process	GO:0046434	232	0.106
monocarboxylic acid metabolic process	GO:0032787	191	0.106
regulation of establishment of planar polarity	GO:0090175	28	0.105
cartilage development	GO:0051216	140	0.104
regulation of cell size	GO:0008361	72	0.103
mesenchymal cell development	GO:0014031	93	0.103
nucleoside metabolic process	GO:0009116	246	0.102
small gtpase mediated signal transduction	GO:0007264	97	0.102
glial cell differentiation	GO:0010001	131	0.102
glutamate receptor signaling pathway	GO:0007215	35	0.101
organelle localization	GO:0051640	179	0.100
organic hydroxy compound metabolic process	GO:1901615	203	0.100
protein processing	GO:0016485	163	0.100
adenylate cyclase modulating g protein coupled receptor signaling pathway	GO:0007188	54	0.100
regulation of saliva secretion	GO:0046877	2	0.100
maintenance of location	GO:0051235	89	0.100
negative regulation of canonical wnt signaling pathway	GO:0090090	51	0.098
learning or memory	GO:0007611	148	0.098
aromatic compound catabolic process	GO:0019439	286	0.098
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.098
morphogenesis of a polarized epithelium	GO:0001738	37	0.097
protein modification by small protein conjugation	GO:0032446	187	0.097	Mouse
ras protein signal transduction	GO:0007265	77	0.097
somatostatin receptor signaling pathway	GO:0038169	2	0.095
microtubule based process	GO:0007017	236	0.095
stem cell development	GO:0048864	219	0.095
gland development	GO:0048732	330	0.095	Zebrafish
visual perception	GO:0007601	52	0.095
regulation of tube size	GO:0035150	57	0.094
regulation of protein targeting	GO:1903533	61	0.094
development of primary sexual characteristics	GO:0045137	143	0.093
limb development	GO:0060173	166	0.093
neuron apoptotic process	GO:0051402	142	0.093
regulation of intracellular transport	GO:0032386	159	0.092
negative regulation of wnt signaling pathway	GO:0030178	73	0.092
regulation of wnt signaling pathway	GO:0030111	123	0.092	Mouse
endocytosis	GO:0006897	168	0.092
retina vasculature development in camera type eye	GO:0061298	17	0.092
regulation of protein serine threonine kinase activity	GO:0071900	157	0.091
iron ion homeostasis	GO:0055072	36	0.091
heterocycle catabolic process	GO:0046700	280	0.091
organonitrogen compound biosynthetic process	GO:1901566	192	0.091
dendrite development	GO:0016358	115	0.091	Fly
hindbrain development	GO:0030902	128	0.090
midgut development	GO:0007494	4	0.090
skin development	GO:0043588	220	0.090
hypothalamus cell differentiation	GO:0021979	8	0.090	Zebrafish
blood vessel morphogenesis	GO:0048514	285	0.090
embryonic skeletal system morphogenesis	GO:0048704	91	0.089
neural tube formation	GO:0001841	108	0.089
positive regulation of wnt signaling pathway	GO:0030177	45	0.089	Mouse
purine containing compound biosynthetic process	GO:0072522	70	0.088
morphogenesis of a branching epithelium	GO:0061138	193	0.088
regulation of metal ion transport	GO:0010959	106	0.088
epithelial cell development	GO:0002064	159	0.087	Mouse
neuronal action potential	GO:0019228	54	0.087
neural crest cell differentiation	GO:0014033	54	0.086
cognition	GO:0050890	149	0.086
embryonic skeletal system development	GO:0048706	120	0.086
monosaccharide transport	GO:0015749	58	0.085
cerebral cortex cell migration	GO:0021795	44	0.084
protein localization to organelle	GO:0033365	185	0.084	Mouse
mitochondrion organization	GO:0007005	134	0.084
protein maturation	GO:0051604	176	0.084
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.084
positive regulation of cellular catabolic process	GO:0031331	148	0.083
positive regulation of angiogenesis	GO:0045766	46	0.083
nuclear transport	GO:0051169	139	0.083	Mouse
tissue remodeling	GO:0048771	102	0.082
generation of precursor metabolites and energy	GO:0006091	103	0.082
positive regulation of neural precursor cell proliferation	GO:2000179	42	0.082
regulation of carbohydrate metabolic process	GO:0006109	75	0.082
regulation of cellular response to stress	GO:0080135	159	0.082	Mouse
organic anion transport	GO:0015711	137	0.082
cytokine production	GO:0001816	319	0.081
tube closure	GO:0060606	91	0.081
limb morphogenesis	GO:0035108	149	0.081
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.080
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.080
nucleoside phosphate biosynthetic process	GO:1901293	79	0.080
carbohydrate catabolic process	GO:0016052	32	0.080
regulation of protein kinase activity	GO:0045859	232	0.079
digestive tract morphogenesis	GO:0048546	147	0.079
positive regulation of apoptotic signaling pathway	GO:2001235	95	0.079
vascular endothelial growth factor receptor signaling pathway	GO:0048010	24	0.079
somatostatin signaling pathway	GO:0038170	2	0.079
anatomical structure homeostasis	GO:0060249	145	0.078
metencephalon development	GO:0022037	89	0.078
negative regulation of transforming growth factor beta receptor signaling pathway	GO:0030512	26	0.078
positive regulation of growth	GO:0045927	104	0.078
positive regulation of gtpase activity	GO:0043547	85	0.078
cell division	GO:0051301	120	0.078
negative regulation of neuron differentiation	GO:0045665	101	0.077
positive regulation of neuron differentiation	GO:0045666	141	0.077
regulation of voltage gated calcium channel activity	GO:1901385	4	0.077
ear development	GO:0043583	200	0.077
purine nucleotide biosynthetic process	GO:0006164	65	0.077
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	61	0.076
urogenital system development	GO:0001655	261	0.076
organonitrogen compound catabolic process	GO:1901565	264	0.076
muscle system process	GO:0003012	141	0.075
regulation of ossification	GO:0030278	112	0.075
innervation	GO:0060384	22	0.075
adenylate cyclase activating g protein coupled receptor signaling pathway	GO:0007189	30	0.075
regulation of neuron apoptotic process	GO:0043523	122	0.075
regulation of chemotaxis	GO:0050920	53	0.074
regulation of cytokine production	GO:0001817	266	0.074
positive regulation of neuron projection development	GO:0010976	79	0.074
lung development	GO:0030324	164	0.074
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger	GO:0007187	55	0.074
negative regulation of cellular protein metabolic process	GO:0032269	247	0.073
b cell activation	GO:0042113	161	0.073
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.073
regulation of vascular endothelial growth factor receptor signaling pathway	GO:0030947	14	0.072
positive regulation of stem cell proliferation	GO:2000648	59	0.072
cell maturation	GO:0048469	127	0.072
ureteric bud development	GO:0001657	94	0.072
nucleoside phosphate catabolic process	GO:1901292	222	0.071
epidermis development	GO:0008544	187	0.071
transition metal ion homeostasis	GO:0055076	54	0.071
gas homeostasis	GO:0033483	3	0.071
chondrocyte differentiation	GO:0002062	72	0.071
positive regulation of cyclic nucleotide biosynthetic process	GO:0030804	24	0.071
mesonephric tubule development	GO:0072164	94	0.071
positive regulation of cell motility	GO:2000147	116	0.070
cellular calcium ion homeostasis	GO:0006874	119	0.070
female sex differentiation	GO:0046660	84	0.070
epithelium migration	GO:0090132	63	0.070
ribose phosphate metabolic process	GO:0019693	291	0.069
t cell differentiation	GO:0030217	174	0.069
cellular response to hormone stimulus	GO:0032870	150	0.067	Fly
regulation of epithelial cell migration	GO:0010632	35	0.067
nucleotide catabolic process	GO:0009166	217	0.067
cerebral cortex gabaergic interneuron differentiation	GO:0021892	9	0.067
regulation of peptide hormone secretion	GO:0090276	75	0.066	Mouse
regulation of purine nucleotide catabolic process	GO:0033121	122	0.066
pancreas development	GO:0031016	57	0.066	Mouse
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.066
acetylcholine transport	GO:0015870	2	0.065
development of primary female sexual characteristics	GO:0046545	73	0.065
action potential	GO:0001508	78	0.065
membrane organization	GO:0061024	245	0.065
regulation of gtp catabolic process	GO:0033124	113	0.064
single organismal cell cell adhesion	GO:0016337	131	0.064	Zebrafish
ribonucleoside catabolic process	GO:0042454	206	0.064
response to peptide hormone	GO:0043434	127	0.064	Fly
hippocampus development	GO:0021766	52	0.064
cell type specific apoptotic process	GO:0097285	268	0.064
ossification	GO:0001503	216	0.063
positive regulation of ras gtpase activity	GO:0032320	65	0.063
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.063
response to extracellular stimulus	GO:0009991	127	0.063
positive regulation of kinase activity	GO:0033674	155	0.062
regulation of muscle system process	GO:0090257	80	0.062
cellular response to organonitrogen compound	GO:0071417	145	0.062	Fly
peptidyl tyrosine phosphorylation	GO:0018108	143	0.062
wound healing	GO:0042060	157	0.062
peptidyl serine modification	GO:0018209	83	0.062
branching morphogenesis of an epithelial tube	GO:0048754	159	0.062
purine ribonucleoside catabolic process	GO:0046130	205	0.061
protein targeting	GO:0006605	143	0.061	Mouse
guanosine containing compound catabolic process	GO:1901069	144	0.061
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.060
vascular process in circulatory system	GO:0003018	62	0.060
renal system development	GO:0072001	225	0.060
calcium ion transport	GO:0006816	159	0.060
thyroid stimulating hormone secreting cell differentiation	GO:0060129	4	0.060
gtp metabolic process	GO:0046039	144	0.060
guanosine containing compound metabolic process	GO:1901068	144	0.060
nucleocytoplasmic transport	GO:0006913	139	0.060	Mouse
camp mediated signaling	GO:0019933	15	0.060
hypothalamus development	GO:0021854	16	0.060	Zebrafish
gtp catabolic process	GO:0006184	143	0.059
regulation of intracellular protein transport	GO:0033157	82	0.059
cell proliferation in hindbrain	GO:0021534	10	0.059
protein modification by small protein conjugation or removal	GO:0070647	207	0.059	Mouse
negative regulation of axon guidance	GO:1902668	8	0.059
oligodendrocyte differentiation	GO:0048709	53	0.059
b cell differentiation	GO:0030183	78	0.058
regulation of apoptotic signaling pathway	GO:2001233	197	0.058
positive regulation of gtp catabolic process	GO:0033126	85	0.058
vesicle localization	GO:0051648	86	0.058
stem cell proliferation	GO:0072089	117	0.058
response to monosaccharide	GO:0034284	67	0.057
regulation of transmembrane transport	GO:0034762	128	0.057
nucleoside triphosphate metabolic process	GO:0009141	230	0.057
regulation of bone mineralization	GO:0030500	31	0.057
multicellular organism growth	GO:0035264	161	0.056
peptide hormone secretion	GO:0030072	109	0.056	Mouse
single fertilization	GO:0007338	82	0.056
development of primary male sexual characteristics	GO:0046546	88	0.056
regulation of neuroblast proliferation	GO:1902692	27	0.056
heart contraction	GO:0060047	93	0.056
cell fate commitment	GO:0045165	210	0.056	Worm
purine nucleoside catabolic process	GO:0006152	205	0.056
regulation of stem cell proliferation	GO:0072091	78	0.055
regulation of organelle organization	GO:0033043	289	0.055
regulation of cellular component biogenesis	GO:0044087	181	0.055
nucleotide biosynthetic process	GO:0009165	78	0.055
regulation of blood vessel size	GO:0050880	56	0.055
cellular protein catabolic process	GO:0044257	155	0.055	Mouse
organic cyclic compound catabolic process	GO:1901361	295	0.055
phenol containing compound metabolic process	GO:0018958	60	0.055
inorganic cation transmembrane transport	GO:0098662	207	0.055
negative regulation of epithelial cell proliferation	GO:0050680	64	0.055
mesonephric epithelium development	GO:0072163	94	0.054
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.054
neural tube closure	GO:0001843	90	0.054
regulation of establishment of protein localization	GO:0070201	181	0.054
regulation of ras protein signal transduction	GO:0046578	114	0.054
purine containing compound catabolic process	GO:0072523	213	0.053
oxidation reduction process	GO:0055114	342	0.053
protein import into nucleus	GO:0006606	95	0.053	Mouse
positive regulation of protein modification process	GO:0031401	299	0.053	Mouse
positive regulation of nucleotide metabolic process	GO:0045981	114	0.053
purine ribonucleotide catabolic process	GO:0009154	208	0.053
rho protein signal transduction	GO:0007266	32	0.053
connective tissue replacement involved in inflammatory response wound healing	GO:0002248	3	0.053
establishment of organelle localization	GO:0051656	122	0.053
t cell differentiation in thymus	GO:0033077	77	0.053
mesoderm development	GO:0007498	100	0.053
regulation of ion transmembrane transporter activity	GO:0032412	54	0.052
positive regulation of nucleotide catabolic process	GO:0030813	88	0.052
establishment of protein localization to organelle	GO:0072594	118	0.052	Mouse
forebrain neuron development	GO:0021884	30	0.052
regulation of purine nucleotide metabolic process	GO:1900542	169	0.052
myelination	GO:0042552	74	0.052
positive regulation of ion transport	GO:0043270	65	0.052
cyclic nucleotide metabolic process	GO:0009187	59	0.052
hypoxia inducible factor 1alpha signaling pathway	GO:0097411	2	0.052
negative regulation of catenin import into nucleus	GO:0035414	2	0.052
peptide secretion	GO:0002790	114	0.051	Mouse
central nervous system neuron development	GO:0021954	67	0.051
smooth muscle contraction	GO:0006939	44	0.051
negative regulation of neuron death	GO:1901215	98	0.051
cranial nerve development	GO:0021545	41	0.051
regulation of smoothened signaling pathway	GO:0008589	58	0.051
regulation of nucleoside metabolic process	GO:0009118	130	0.050
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090101	61	0.050
positive regulation of apoptotic process	GO:0043065	217	0.050
wnt signaling pathway	GO:0016055	188	0.050	Mouse
respiratory system development	GO:0060541	190	0.050
negative regulation of neuron projection development	GO:0010977	50	0.050
establishment of protein localization to membrane	GO:0090150	54	0.049
single organism nuclear import	GO:1902593	95	0.049	Mouse
regulation of kinase activity	GO:0043549	249	0.049
hormone metabolic process	GO:0042445	86	0.049
regulation of stress activated mapk cascade	GO:0032872	69	0.049
myeloid cell differentiation	GO:0030099	233	0.049
eye photoreceptor cell differentiation	GO:0001754	41	0.049	Fly
response to radiation	GO:0009314	165	0.048
positive regulation of protein transport	GO:0051222	93	0.048
bronchiole morphogenesis	GO:0060436	1	0.048
glucose transport	GO:0015758	56	0.047
cytosolic calcium ion homeostasis	GO:0051480	70	0.047
determination of left right symmetry	GO:0007368	80	0.047
exocytosis	GO:0006887	121	0.047
neural fold elevation formation	GO:0021502	1	0.047
regulation of epithelial cell proliferation	GO:0050678	141	0.047
hair cycle	GO:0042633	90	0.046
positive regulation of response to wounding	GO:1903036	66	0.046
sulfur compound metabolic process	GO:0006790	100	0.046
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.046
positive regulation of neuroblast proliferation	GO:0002052	19	0.046
transforming growth factor beta receptor signaling pathway	GO:0007179	71	0.046
positive regulation of epithelial cell proliferation	GO:0050679	68	0.046
plasma membrane organization	GO:0007009	90	0.046
regulation of cyclic nucleotide metabolic process	GO:0030799	40	0.045
inner ear morphogenesis	GO:0042472	101	0.045
retina development in camera type eye	GO:0060041	119	0.045
regulation of response to wounding	GO:1903034	189	0.044
amino acid transmembrane transport	GO:0003333	37	0.044
positive regulation of hormone secretion	GO:0046887	38	0.044
single organism cell adhesion	GO:0098602	156	0.044	Zebrafish
regulation of cell activation	GO:0050865	289	0.044
regulation of canonical wnt signaling pathway	GO:0060828	82	0.044	Mouse
hexose metabolic process	GO:0019318	98	0.044
somatotropin secreting cell differentiation	GO:0060126	4	0.044
negative regulation of cell growth	GO:0030308	44	0.044
positive regulation of protein kinase activity	GO:0045860	144	0.044
multicellular organismal signaling	GO:0035637	91	0.044
modification dependent macromolecule catabolic process	GO:0043632	133	0.043	Mouse
lateral inhibition	GO:0046331	1	0.043
epithelial cell proliferation	GO:0050673	174	0.043
cellular ketone metabolic process	GO:0042180	84	0.043
regulation of high voltage gated calcium channel activity	GO:1901841	2	0.043
motor neuron axon guidance	GO:0008045	26	0.043
cell recognition	GO:0008037	83	0.043
positive regulation of cell cycle	GO:0045787	92	0.042
regulation of heart rate	GO:0002027	36	0.042
purine ribonucleotide biosynthetic process	GO:0009152	59	0.042
positive regulation of voltage gated calcium channel activity	GO:1901387	2	0.042
mitochondrion distribution	GO:0048311	4	0.042
regulation of cell cycle	GO:0051726	281	0.042	Mouse
mechanoreceptor differentiation	GO:0042490	67	0.042
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.042
associative learning	GO:0008306	61	0.042
response to light stimulus	GO:0009416	135	0.041
cellular response to monosaccharide stimulus	GO:0071326	47	0.041
nucleoside catabolic process	GO:0009164	206	0.041
positive regulation of cell projection organization	GO:0031346	95	0.041
negative regulation of phosphorus metabolic process	GO:0010563	184	0.041
columnar cuboidal epithelial cell maturation	GO:0002069	4	0.041
response to nutrient levels	GO:0031667	109	0.041
protein kinase b signaling	GO:0043491	74	0.041
b cell homeostasis	GO:0001782	34	0.041
establishment of neuroblast polarity	GO:0045200	1	0.041
camp metabolic process	GO:0046058	40	0.040
regulation of protein maturation	GO:1903317	96	0.040
circadian rhythm	GO:0007623	114	0.040	Mouse
spinal cord development	GO:0021510	81	0.040
heart process	GO:0003015	94	0.040

Arnt2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.064
nervous system disease	DOID:863	0.064
central nervous system disease	DOID:331	0.061
disease of metabolism	DOID:0014667	0.061

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