| mrna splicing via spliceosome | GO:0000398 | 43 | 0.416 | Human |
| alternative mrna splicing via spliceosome | GO:0000380 | 12 | 0.331 | Human |
| establishment of rna localization | GO:0051236 | 18 | 0.330 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.302 | |
| mrna metabolic process | GO:0016071 | 84 | 0.274 | Human |
| transcription coupled nucleotide excision repair | GO:0006283 | 2 | 0.247 | |
| positive regulation of mrna splicing via spliceosome | GO:0048026 | 11 | 0.242 | |
| dna dealkylation | GO:0035510 | 11 | 0.179 | |
| regulation of rna splicing | GO:0043484 | 37 | 0.173 | Human |
| regulation of mrna processing | GO:0050684 | 41 | 0.165 | Human |
| cytoplasmic transport | GO:0016482 | 234 | 0.158 | |
| rna splicing via transesterification reactions with bulged adenosine as nucleophile | GO:0000377 | 43 | 0.156 | Human |
| dna repair | GO:0006281 | 107 | 0.143 | |
| mrna transport | GO:0051028 | 13 | 0.139 | |
| regulation of mrna stability | GO:0043488 | 23 | 0.131 | |
| pole plasm assembly | GO:0007315 | 2 | 0.121 | |
| rna splicing via transesterification reactions | GO:0000375 | 43 | 0.121 | Human |
| oocyte anterior posterior axis specification | GO:0007314 | 2 | 0.113 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.111 | |
| mrna processing | GO:0006397 | 63 | 0.109 | Human |
| regulation of mrna splicing via spliceosome | GO:0048024 | 32 | 0.108 | Human |
| organelle fission | GO:0048285 | 170 | 0.099 | Worm |
| positive regulation of intracellular transport | GO:0032388 | 70 | 0.097 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 73 | 0.094 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.088 | |
| regulation of protein localization | GO:0032880 | 231 | 0.088 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.085 | |
| histone methylation | GO:0016571 | 71 | 0.084 | |
| positive regulation of rna splicing | GO:0033120 | 12 | 0.082 | |
| dna modification | GO:0006304 | 50 | 0.081 | |
| rna splicing | GO:0008380 | 54 | 0.081 | Human |
| translation | GO:0006412 | 93 | 0.081 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.080 | |
| regulation of intracellular protein transport | GO:0033157 | 82 | 0.077 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.071 | |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.070 | |
| rna transport | GO:0050658 | 18 | 0.066 | |
| mrna export from nucleus | GO:0006406 | 11 | 0.064 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.064 | |
| positive regulation of dna templated transcription elongation | GO:0032786 | 2 | 0.063 | |
| nuclear transport | GO:0051169 | 139 | 0.061 | |
| demethylation | GO:0070988 | 23 | 0.061 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.060 | |
| germ cell development | GO:0007281 | 185 | 0.060 | Worm |
| regulation of protein transport | GO:0051223 | 163 | 0.059 | |
| positive regulation of intracellular protein transport | GO:0090316 | 42 | 0.058 | |
| protein methylation | GO:0006479 | 81 | 0.058 | |
| nucleobase containing compound transport | GO:0015931 | 27 | 0.058 | |
| oxidation reduction process | GO:0055114 | 342 | 0.058 | |
| histone lysine methylation | GO:0034968 | 50 | 0.057 | |
| oogenesis | GO:0048477 | 56 | 0.056 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.055 | |
| nucleic acid transport | GO:0050657 | 18 | 0.054 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.052 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.051 | |
| rna processing | GO:0006396 | 105 | 0.050 | Human |
| negative regulation of mrna processing | GO:0050686 | 12 | 0.049 | Human |
| mitotic cell cycle process | GO:1903047 | 159 | 0.049 | |
| rna localization | GO:0006403 | 23 | 0.049 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.048 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.045 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.045 | Worm |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.044 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.043 | |
| regulation of mrna metabolic process | GO:1903311 | 43 | 0.042 | Human |
| multicellular organismal signaling | GO:0035637 | 91 | 0.041 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.040 | |
| axonogenesis | GO:0007409 | 274 | 0.040 | |
| positive regulation of nucleocytoplasmic transport | GO:0046824 | 30 | 0.039 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.037 | |
| regulation of histone methylation | GO:0031060 | 30 | 0.036 | |
| ribonucleoprotein complex subunit organization | GO:0071826 | 28 | 0.036 | |
| regionalization | GO:0003002 | 337 | 0.036 | |
| intracellular protein transport | GO:0006886 | 204 | 0.036 | |
| intracellular mrna localization | GO:0008298 | 4 | 0.034 | |
| chromatin modification | GO:0016568 | 187 | 0.034 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.034 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.033 | |
| regulation of rna stability | GO:0043487 | 26 | 0.032 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.032 | |
| maternal determination of anterior posterior axis embryo | GO:0008358 | 2 | 0.032 | |
| spermatogenesis | GO:0007283 | 284 | 0.031 | |
| oocyte axis specification | GO:0007309 | 2 | 0.031 | |
| regulation of cell division | GO:0051302 | 76 | 0.031 | Worm |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.031 | |
| spermatid development | GO:0007286 | 108 | 0.030 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.030 | |
| axon guidance | GO:0007411 | 141 | 0.030 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.030 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.030 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.029 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.028 | |
| hematopoietic progenitor cell differentiation | GO:0002244 | 143 | 0.028 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.028 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.028 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.027 | |
| regulation of translation | GO:0006417 | 71 | 0.027 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.027 | |
| oocyte construction | GO:0007308 | 2 | 0.027 | |
| macromolecule methylation | GO:0043414 | 120 | 0.027 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.027 | Human |
| transmission of nerve impulse | GO:0019226 | 76 | 0.027 | |
| mesenchymal cell development | GO:0014031 | 93 | 0.026 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.026 | |
| regulation of alternative mrna splicing via spliceosome | GO:0000381 | 8 | 0.026 | Human |
| protein import into nucleus | GO:0006606 | 95 | 0.025 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.025 | Human |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.025 | |
| amine metabolic process | GO:0009308 | 45 | 0.025 | |
| single organism nuclear import | GO:1902593 | 95 | 0.025 | |
| male gamete generation | GO:0048232 | 285 | 0.024 | |
| positive regulation of mrna processing | GO:0050685 | 16 | 0.024 | |
| protein targeting | GO:0006605 | 143 | 0.024 | |
| cardiac muscle contraction | GO:0060048 | 32 | 0.024 | |
| dna metabolic process | GO:0006259 | 303 | 0.024 | |
| protein import | GO:0017038 | 101 | 0.024 | |
| dna templated transcription termination | GO:0006353 | 4 | 0.024 | |
| positive regulation of protein transport | GO:0051222 | 93 | 0.023 | |
| protein alkylation | GO:0008213 | 81 | 0.023 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.023 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.023 | |
| signal transduction by p53 class mediator | GO:0072331 | 51 | 0.023 | |
| female gamete generation | GO:0007292 | 74 | 0.023 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.022 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.022 | Worm |
| chemotaxis | GO:0006935 | 247 | 0.022 | |
| nuclear export | GO:0051168 | 34 | 0.022 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 91 | 0.022 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.022 | |
| regulation of nucleotide metabolic process | GO:0006140 | 169 | 0.022 | |
| segmentation | GO:0035282 | 93 | 0.022 | |
| regulation of histone h3 k4 methylation | GO:0051569 | 12 | 0.022 | |
| organophosphate biosynthetic process | GO:0090407 | 122 | 0.021 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.021 | |
| positive regulation of translation | GO:0045727 | 19 | 0.021 | |
| blood circulation | GO:0008015 | 195 | 0.021 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.021 | |
| camera type eye development | GO:0043010 | 266 | 0.021 | |
| spliceosomal complex assembly | GO:0000245 | 6 | 0.020 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.020 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.020 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.020 | Human |
| chromatin organization | GO:0006325 | 206 | 0.020 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.020 | Human |
| regulation of transcription by chromatin organization | GO:0034401 | 0 | 0.020 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.019 | |
| olfactory learning | GO:0008355 | 2 | 0.019 | |
| protein ubiquitination | GO:0016567 | 171 | 0.019 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.019 | |
| cation transport | GO:0006812 | 399 | 0.019 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.019 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.019 | Human |
| regulation of nucleotide catabolic process | GO:0030811 | 122 | 0.019 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.019 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.019 | |
| dna demethylation | GO:0080111 | 10 | 0.019 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.019 | |
| establishment or maintenance of cytoskeleton polarity | GO:0030952 | 2 | 0.019 | |
| carboxylic acid biosynthetic process | GO:0046394 | 86 | 0.019 | |
| alpha amino acid metabolic process | GO:1901605 | 59 | 0.019 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.019 | |
| spermatid differentiation | GO:0048515 | 115 | 0.019 | |
| nuclear import | GO:0051170 | 95 | 0.019 | |
| dephosphorylation | GO:0016311 | 129 | 0.018 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.018 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 114 | 0.018 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.018 | |
| regulation of myeloid cell differentiation | GO:0045637 | 96 | 0.018 | |
| regulation of neuron projection development | GO:0010975 | 169 | 0.018 | |
| regulation of ion transmembrane transporter activity | GO:0032412 | 54 | 0.018 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.018 | Human |
| ribose phosphate biosynthetic process | GO:0046390 | 59 | 0.018 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.018 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.018 | |
| regulation of protein binding | GO:0043393 | 60 | 0.018 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.017 | |
| circulatory system process | GO:0003013 | 197 | 0.017 | |
| positive regulation of sequence specific dna binding transcription factor activity | GO:0051091 | 68 | 0.017 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.017 | |
| transmembrane transport | GO:0055085 | 412 | 0.017 | |
| regulation of protein targeting | GO:1903533 | 61 | 0.017 | |
| membrane organization | GO:0061024 | 245 | 0.017 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.017 | |
| multi multicellular organism process | GO:0044706 | 109 | 0.016 | |
| establishment or maintenance of microtubule cytoskeleton polarity | GO:0030951 | 1 | 0.016 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.016 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.016 | |
| methylation | GO:0032259 | 134 | 0.016 | |
| positive regulation of mrna metabolic process | GO:1903313 | 17 | 0.016 | |
| sequestering of calcium ion | GO:0051208 | 18 | 0.016 | |
| protein localization to nucleus | GO:0034504 | 121 | 0.016 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 0 | 0.016 | |
| regulation of gtp catabolic process | GO:0033124 | 113 | 0.016 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.016 | |
| protein dna complex subunit organization | GO:0071824 | 28 | 0.016 | |
| connective tissue development | GO:0061448 | 179 | 0.016 | |
| neuron projection guidance | GO:0097485 | 141 | 0.016 | |
| heart morphogenesis | GO:0003007 | 178 | 0.016 | |
| divalent metal ion transport | GO:0070838 | 172 | 0.015 | |
| engulfment of apoptotic cell | GO:0043652 | 3 | 0.015 | |
| positive regulation of cytoplasmic transport | GO:1903651 | 40 | 0.015 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.015 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.015 | |
| nucleotide biosynthetic process | GO:0009165 | 78 | 0.015 | |
| response to nutrient levels | GO:0031667 | 109 | 0.015 | |
| mesenchyme development | GO:0060485 | 152 | 0.015 | |
| cellular response to amino acid stimulus | GO:0071230 | 29 | 0.015 | |
| regulation of insulin receptor signaling pathway | GO:0046626 | 21 | 0.015 | |
| maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna | GO:0000463 | 1 | 0.015 | |
| purine containing compound biosynthetic process | GO:0072522 | 70 | 0.015 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.015 | Human |
| nuclear division | GO:0000280 | 158 | 0.015 | Worm |
| regulation of homeostatic process | GO:0032844 | 182 | 0.015 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.015 | |
| dna dependent dna replication maintenance of fidelity | GO:0045005 | 3 | 0.015 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.014 | |
| leukocyte proliferation | GO:0070661 | 172 | 0.014 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.014 | Human |
| nucleoside phosphate biosynthetic process | GO:1901293 | 79 | 0.014 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.014 | |
| positive regulation of protein export from nucleus | GO:0046827 | 4 | 0.014 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 114 | 0.014 | |
| regulation of ion transport | GO:0043269 | 215 | 0.014 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.014 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.014 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.014 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.014 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.014 | |
| circadian rhythm | GO:0007623 | 114 | 0.014 | |
| regulation of multi organism process | GO:0043900 | 111 | 0.014 | |
| mitotic nuclear division | GO:0007067 | 48 | 0.014 | |
| cognition | GO:0050890 | 149 | 0.014 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.014 | |
| placenta development | GO:0001890 | 140 | 0.014 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 88 | 0.014 | |
| mesenchymal cell differentiation | GO:0048762 | 107 | 0.014 | |
| negative regulation of mrna splicing via spliceosome | GO:0048025 | 12 | 0.013 | Human |
| neuronal action potential | GO:0019228 | 54 | 0.013 | |
| regulation of transmembrane transport | GO:0034762 | 128 | 0.013 | |
| regulation of map kinase activity | GO:0043405 | 120 | 0.013 | |
| cellular homeostasis | GO:0019725 | 240 | 0.013 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.013 | |
| cell maturation | GO:0048469 | 127 | 0.013 | |
| organic acid biosynthetic process | GO:0016053 | 86 | 0.013 | |
| action potential | GO:0001508 | 78 | 0.013 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.013 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.013 | Human |
| microtubule based process | GO:0007017 | 236 | 0.013 | |
| negative regulation of cell cycle | GO:0045786 | 123 | 0.013 | |
| regulation of ion transmembrane transport | GO:0034765 | 119 | 0.013 | |
| positive regulation of histone h3 k4 methylation | GO:0051571 | 5 | 0.013 | |
| atp metabolic process | GO:0046034 | 75 | 0.013 | |
| regulation of chromatin binding | GO:0035561 | 7 | 0.013 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.013 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.012 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.012 | |
| heart contraction | GO:0060047 | 93 | 0.012 | |
| circadian regulation of gene expression | GO:0032922 | 48 | 0.012 | |
| positive regulation of transcription elongation from rna polymerase ii promoter | GO:0032968 | 2 | 0.012 | |
| calcium ion transport | GO:0006816 | 159 | 0.012 | |
| histone h3 k36 demethylation | GO:0070544 | 2 | 0.012 | |
| negative regulation of protein phosphorylation | GO:0001933 | 126 | 0.012 | |
| development of primary sexual characteristics | GO:0045137 | 143 | 0.012 | |
| intracellular receptor signaling pathway | GO:0030522 | 74 | 0.012 | |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.012 | |
| epithelial to mesenchymal transition | GO:0001837 | 47 | 0.012 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.012 | |
| regulation of nucleoside metabolic process | GO:0009118 | 130 | 0.012 | |
| coenzyme metabolic process | GO:0006732 | 52 | 0.012 | |
| symbiosis encompassing mutualism through parasitism | GO:0044403 | 83 | 0.012 | |
| negative regulation of cell development | GO:0010721 | 169 | 0.012 | |
| maternal placenta development | GO:0001893 | 20 | 0.012 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.012 | Worm |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.012 | |
| base excision repair | GO:0006284 | 9 | 0.012 | |
| regulation of muscle system process | GO:0090257 | 80 | 0.012 | |
| response to extracellular stimulus | GO:0009991 | 127 | 0.012 | |
| protein localization to organelle | GO:0033365 | 185 | 0.012 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 57 | 0.012 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.012 | |
| cellular response to hormone stimulus | GO:0032870 | 150 | 0.011 | |
| negative regulation of nervous system development | GO:0051961 | 156 | 0.011 | |
| muscle contraction | GO:0006936 | 101 | 0.011 | |
| regulation of binding | GO:0051098 | 111 | 0.011 | |
| dna hypermethylation | GO:0044026 | 3 | 0.011 | |
| inflammatory response | GO:0006954 | 244 | 0.011 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.011 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 73 | 0.011 | |
| maintenance of location | GO:0051235 | 89 | 0.011 | |
| 3 utr mediated mrna stabilization | GO:0070935 | 2 | 0.011 | |
| sequestering of metal ion | GO:0051238 | 19 | 0.011 | |
| forebrain development | GO:0030900 | 302 | 0.011 | |
| embryonic organ morphogenesis | GO:0048562 | 276 | 0.011 | |
| multicellular organismal homeostasis | GO:0048871 | 164 | 0.011 | |
| striated muscle contraction | GO:0006941 | 45 | 0.011 | |
| cell division | GO:0051301 | 120 | 0.011 | Worm |
| skeletal system development | GO:0001501 | 356 | 0.011 | |
| respiratory system development | GO:0060541 | 190 | 0.010 | |
| regulation of cell morphogenesis involved in differentiation | GO:0010769 | 151 | 0.010 | |
| response to acid chemical | GO:0001101 | 111 | 0.010 | |
| cofactor metabolic process | GO:0051186 | 80 | 0.010 | |
| formation of organ boundary | GO:0010160 | 1 | 0.010 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.010 | |
| neuron death | GO:0070997 | 154 | 0.010 | |
| muscle system process | GO:0003012 | 141 | 0.010 | |
| regulation of system process | GO:0044057 | 200 | 0.010 | |
| histone h3 k4 methylation | GO:0051568 | 23 | 0.010 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.010 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.010 | |
| negative regulation of rna splicing | GO:0033119 | 12 | 0.010 | Human |