IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Rnps1

ribonucleic acid binding protein S1

Ensembl: ENSMUSG00000034681
Entrez: 19826
UniProtKB: Q99M28

Process Predictions
Disease Predictions

Rnps1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
mrna splicing via spliceosome	GO:0000398	43	0.416	Human
alternative mrna splicing via spliceosome	GO:0000380	12	0.331	Human
establishment of rna localization	GO:0051236	18	0.330
regulation of intracellular transport	GO:0032386	159	0.302
mrna metabolic process	GO:0016071	84	0.274	Human
transcription coupled nucleotide excision repair	GO:0006283	2	0.247
positive regulation of mrna splicing via spliceosome	GO:0048026	11	0.242
dna dealkylation	GO:0035510	11	0.179
regulation of rna splicing	GO:0043484	37	0.173	Human
regulation of mrna processing	GO:0050684	41	0.165	Human
cytoplasmic transport	GO:0016482	234	0.158
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	43	0.156	Human
dna repair	GO:0006281	107	0.143
mrna transport	GO:0051028	13	0.139
regulation of mrna stability	GO:0043488	23	0.131
pole plasm assembly	GO:0007315	2	0.121
rna splicing via transesterification reactions	GO:0000375	43	0.121	Human
oocyte anterior posterior axis specification	GO:0007314	2	0.113
nitrogen compound transport	GO:0071705	271	0.111
mrna processing	GO:0006397	63	0.109	Human
regulation of mrna splicing via spliceosome	GO:0048024	32	0.108	Human
organelle fission	GO:0048285	170	0.099	Worm
positive regulation of intracellular transport	GO:0032388	70	0.097
regulation of nucleocytoplasmic transport	GO:0046822	73	0.094
regulation of hydrolase activity	GO:0051336	246	0.088
regulation of protein localization	GO:0032880	231	0.088
cellular response to dna damage stimulus	GO:0006974	207	0.085
histone methylation	GO:0016571	71	0.084
positive regulation of rna splicing	GO:0033120	12	0.082
dna modification	GO:0006304	50	0.081
rna splicing	GO:0008380	54	0.081	Human
translation	GO:0006412	93	0.081
nucleocytoplasmic transport	GO:0006913	139	0.080
regulation of intracellular protein transport	GO:0033157	82	0.077
cellular amino acid metabolic process	GO:0006520	103	0.071
regulation of cytoplasmic transport	GO:1903649	112	0.070
rna transport	GO:0050658	18	0.066
mrna export from nucleus	GO:0006406	11	0.064
purine containing compound metabolic process	GO:0072521	311	0.064
positive regulation of dna templated transcription elongation	GO:0032786	2	0.063
nuclear transport	GO:0051169	139	0.061
demethylation	GO:0070988	23	0.061
nucleoside metabolic process	GO:0009116	246	0.060
germ cell development	GO:0007281	185	0.060	Worm
regulation of protein transport	GO:0051223	163	0.059
positive regulation of intracellular protein transport	GO:0090316	42	0.058
protein methylation	GO:0006479	81	0.058
nucleobase containing compound transport	GO:0015931	27	0.058
oxidation reduction process	GO:0055114	342	0.058
histone lysine methylation	GO:0034968	50	0.057
oogenesis	GO:0048477	56	0.056
glycosyl compound metabolic process	GO:1901657	246	0.055
nucleic acid transport	GO:0050657	18	0.054
negative regulation of cellular protein metabolic process	GO:0032269	247	0.052
negative regulation of molecular function	GO:0044092	258	0.051
rna processing	GO:0006396	105	0.050	Human
negative regulation of mrna processing	GO:0050686	12	0.049	Human
mitotic cell cycle process	GO:1903047	159	0.049
rna localization	GO:0006403	23	0.049
negative regulation of protein modification process	GO:0031400	163	0.048
nucleoside phosphate metabolic process	GO:0006753	338	0.045
regulation of organelle organization	GO:0033043	289	0.045	Worm
regulation of establishment of protein localization	GO:0070201	181	0.044
lymphocyte proliferation	GO:0046651	164	0.043
regulation of mrna metabolic process	GO:1903311	43	0.042	Human
multicellular organismal signaling	GO:0035637	91	0.041
actin cytoskeleton organization	GO:0030036	220	0.040
axonogenesis	GO:0007409	274	0.040
positive regulation of nucleocytoplasmic transport	GO:0046824	30	0.039
regulation of purine nucleotide metabolic process	GO:1900542	169	0.037
regulation of histone methylation	GO:0031060	30	0.036
ribonucleoprotein complex subunit organization	GO:0071826	28	0.036
regionalization	GO:0003002	337	0.036
intracellular protein transport	GO:0006886	204	0.036
intracellular mrna localization	GO:0008298	4	0.034
chromatin modification	GO:0016568	187	0.034
posttranscriptional regulation of gene expression	GO:0010608	155	0.034
ribonucleoside metabolic process	GO:0009119	245	0.033
regulation of rna stability	GO:0043487	26	0.032
mitotic cell cycle	GO:0000278	195	0.032
maternal determination of anterior posterior axis embryo	GO:0008358	2	0.032
spermatogenesis	GO:0007283	284	0.031
oocyte axis specification	GO:0007309	2	0.031
regulation of cell division	GO:0051302	76	0.031	Worm
regulation of cellular amino acid metabolic process	GO:0006521	5	0.031
spermatid development	GO:0007286	108	0.030
purine ribonucleoside metabolic process	GO:0046128	241	0.030
axon guidance	GO:0007411	141	0.030
negative regulation of intracellular signal transduction	GO:1902532	167	0.030
positive regulation of protein modification process	GO:0031401	299	0.030
protein modification by small protein conjugation or removal	GO:0070647	207	0.029
nucleotide metabolic process	GO:0009117	332	0.028
hematopoietic progenitor cell differentiation	GO:0002244	143	0.028
negative regulation of cell proliferation	GO:0008285	296	0.028
nucleoside triphosphate metabolic process	GO:0009141	230	0.028
microtubule cytoskeleton organization	GO:0000226	157	0.027
regulation of translation	GO:0006417	71	0.027
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.027
oocyte construction	GO:0007308	2	0.027
macromolecule methylation	GO:0043414	120	0.027
cellular macromolecule catabolic process	GO:0044265	206	0.027	Human
transmission of nerve impulse	GO:0019226	76	0.027
mesenchymal cell development	GO:0014031	93	0.026
purine nucleoside metabolic process	GO:0042278	241	0.026
regulation of alternative mrna splicing via spliceosome	GO:0000381	8	0.026	Human
protein import into nucleus	GO:0006606	95	0.025
aromatic compound catabolic process	GO:0019439	286	0.025	Human
cellular response to cytokine stimulus	GO:0071345	189	0.025
amine metabolic process	GO:0009308	45	0.025
single organism nuclear import	GO:1902593	95	0.025
male gamete generation	GO:0048232	285	0.024
positive regulation of mrna processing	GO:0050685	16	0.024
protein targeting	GO:0006605	143	0.024
cardiac muscle contraction	GO:0060048	32	0.024
dna metabolic process	GO:0006259	303	0.024
protein import	GO:0017038	101	0.024
dna templated transcription termination	GO:0006353	4	0.024
positive regulation of protein transport	GO:0051222	93	0.023
protein alkylation	GO:0008213	81	0.023
response to organonitrogen compound	GO:0010243	246	0.023
negative regulation of protein metabolic process	GO:0051248	282	0.023
signal transduction by p53 class mediator	GO:0072331	51	0.023
female gamete generation	GO:0007292	74	0.023
protein modification by small protein conjugation	GO:0032446	187	0.022
regulation of cell cycle	GO:0051726	281	0.022	Worm
chemotaxis	GO:0006935	247	0.022
nuclear export	GO:0051168	34	0.022
positive regulation of nucleoside metabolic process	GO:0045979	91	0.022
ion transmembrane transport	GO:0034220	361	0.022
regulation of nucleotide metabolic process	GO:0006140	169	0.022
segmentation	GO:0035282	93	0.022
regulation of histone h3 k4 methylation	GO:0051569	12	0.022
organophosphate biosynthetic process	GO:0090407	122	0.021
ribonucleoside catabolic process	GO:0042454	206	0.021
positive regulation of translation	GO:0045727	19	0.021
blood circulation	GO:0008015	195	0.021
nucleobase containing small molecule metabolic process	GO:0055086	352	0.021
camera type eye development	GO:0043010	266	0.021
spliceosomal complex assembly	GO:0000245	6	0.020
sensory organ morphogenesis	GO:0090596	242	0.020
cellular amine metabolic process	GO:0044106	44	0.020
positive regulation of programmed cell death	GO:0043068	218	0.020	Human
chromatin organization	GO:0006325	206	0.020
positive regulation of apoptotic process	GO:0043065	217	0.020	Human
regulation of transcription by chromatin organization	GO:0034401	0	0.020
positive regulation of organelle organization	GO:0010638	128	0.019
olfactory learning	GO:0008355	2	0.019
protein ubiquitination	GO:0016567	171	0.019
cellular protein complex assembly	GO:0043623	116	0.019
cation transport	GO:0006812	399	0.019
ribonucleotide metabolic process	GO:0009259	291	0.019
positive regulation of cell death	GO:0010942	224	0.019	Human
regulation of nucleotide catabolic process	GO:0030811	122	0.019
negative regulation of phosphorus metabolic process	GO:0010563	184	0.019
negative regulation of phosphate metabolic process	GO:0045936	184	0.019
dna demethylation	GO:0080111	10	0.019
regulation of hormone levels	GO:0010817	211	0.019
establishment or maintenance of cytoskeleton polarity	GO:0030952	2	0.019
carboxylic acid biosynthetic process	GO:0046394	86	0.019
alpha amino acid metabolic process	GO:1901605	59	0.019
establishment of protein localization to organelle	GO:0072594	118	0.019
spermatid differentiation	GO:0048515	115	0.019
nuclear import	GO:0051170	95	0.019
dephosphorylation	GO:0016311	129	0.018
ribose phosphate metabolic process	GO:0019693	291	0.018
positive regulation of nucleotide metabolic process	GO:0045981	114	0.018
carbohydrate derivative biosynthetic process	GO:1901137	183	0.018
regulation of myeloid cell differentiation	GO:0045637	96	0.018
regulation of neuron projection development	GO:0010975	169	0.018
regulation of ion transmembrane transporter activity	GO:0032412	54	0.018
macromolecule catabolic process	GO:0009057	281	0.018	Human
ribose phosphate biosynthetic process	GO:0046390	59	0.018
purine nucleotide metabolic process	GO:0006163	302	0.018
regulation of membrane potential	GO:0042391	192	0.018
regulation of protein binding	GO:0043393	60	0.018
cellular response to organonitrogen compound	GO:0071417	145	0.017
circulatory system process	GO:0003013	197	0.017
positive regulation of sequence specific dna binding transcription factor activity	GO:0051091	68	0.017
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.017
transmembrane transport	GO:0055085	412	0.017
regulation of protein targeting	GO:1903533	61	0.017
membrane organization	GO:0061024	245	0.017
peptidyl amino acid modification	GO:0018193	336	0.017
multi multicellular organism process	GO:0044706	109	0.016
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	1	0.016
cation transmembrane transport	GO:0098655	266	0.016
small gtpase mediated signal transduction	GO:0007264	97	0.016
methylation	GO:0032259	134	0.016
positive regulation of mrna metabolic process	GO:1903313	17	0.016
sequestering of calcium ion	GO:0051208	18	0.016
protein localization to nucleus	GO:0034504	121	0.016
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.016
regulation of gtp catabolic process	GO:0033124	113	0.016
purine nucleoside catabolic process	GO:0006152	205	0.016
protein dna complex subunit organization	GO:0071824	28	0.016
connective tissue development	GO:0061448	179	0.016
neuron projection guidance	GO:0097485	141	0.016
heart morphogenesis	GO:0003007	178	0.016
divalent metal ion transport	GO:0070838	172	0.015
engulfment of apoptotic cell	GO:0043652	3	0.015
positive regulation of cytoplasmic transport	GO:1903651	40	0.015
ras protein signal transduction	GO:0007265	77	0.015
regulation of cellular component biogenesis	GO:0044087	181	0.015
nucleotide biosynthetic process	GO:0009165	78	0.015
response to nutrient levels	GO:0031667	109	0.015
mesenchyme development	GO:0060485	152	0.015
cellular response to amino acid stimulus	GO:0071230	29	0.015
regulation of insulin receptor signaling pathway	GO:0046626	21	0.015
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna	GO:0000463	1	0.015
purine containing compound biosynthetic process	GO:0072522	70	0.015
cellular nitrogen compound catabolic process	GO:0044270	280	0.015	Human
nuclear division	GO:0000280	158	0.015	Worm
regulation of homeostatic process	GO:0032844	182	0.015
positive regulation of cellular amine metabolic process	GO:0033240	5	0.015
dna dependent dna replication maintenance of fidelity	GO:0045005	3	0.015
nucleotide catabolic process	GO:0009166	217	0.014
leukocyte proliferation	GO:0070661	172	0.014
organic cyclic compound catabolic process	GO:1901361	295	0.014	Human
nucleoside phosphate biosynthetic process	GO:1901293	79	0.014
intrinsic apoptotic signaling pathway	GO:0097193	132	0.014
positive regulation of protein export from nucleus	GO:0046827	4	0.014
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.014
regulation of ion transport	GO:0043269	215	0.014
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.014
apoptotic signaling pathway	GO:0097190	306	0.014
regulation of cellular response to stress	GO:0080135	159	0.014
regulation of protein kinase activity	GO:0045859	232	0.014
positive regulation of hydrolase activity	GO:0051345	148	0.014
circadian rhythm	GO:0007623	114	0.014
regulation of multi organism process	GO:0043900	111	0.014
mitotic nuclear division	GO:0007067	48	0.014
cognition	GO:0050890	149	0.014
epithelial cell proliferation	GO:0050673	174	0.014
placenta development	GO:0001890	140	0.014
positive regulation of purine nucleotide catabolic process	GO:0033123	88	0.014
mesenchymal cell differentiation	GO:0048762	107	0.014
negative regulation of mrna splicing via spliceosome	GO:0048025	12	0.013	Human
neuronal action potential	GO:0019228	54	0.013
regulation of transmembrane transport	GO:0034762	128	0.013
regulation of map kinase activity	GO:0043405	120	0.013
cellular homeostasis	GO:0019725	240	0.013
organonitrogen compound biosynthetic process	GO:1901566	192	0.013
cell maturation	GO:0048469	127	0.013
organic acid biosynthetic process	GO:0016053	86	0.013
action potential	GO:0001508	78	0.013
purine containing compound catabolic process	GO:0072523	213	0.013
heterocycle catabolic process	GO:0046700	280	0.013	Human
microtubule based process	GO:0007017	236	0.013
negative regulation of cell cycle	GO:0045786	123	0.013
regulation of ion transmembrane transport	GO:0034765	119	0.013
positive regulation of histone h3 k4 methylation	GO:0051571	5	0.013
atp metabolic process	GO:0046034	75	0.013
regulation of chromatin binding	GO:0035561	7	0.013
negative regulation of phosphorylation	GO:0042326	166	0.013
ribonucleotide catabolic process	GO:0009261	208	0.012
purine nucleotide catabolic process	GO:0006195	211	0.012
heart contraction	GO:0060047	93	0.012
circadian regulation of gene expression	GO:0032922	48	0.012
positive regulation of transcription elongation from rna polymerase ii promoter	GO:0032968	2	0.012
calcium ion transport	GO:0006816	159	0.012
histone h3 k36 demethylation	GO:0070544	2	0.012
negative regulation of protein phosphorylation	GO:0001933	126	0.012
development of primary sexual characteristics	GO:0045137	143	0.012
intracellular receptor signaling pathway	GO:0030522	74	0.012
regulation of neuron differentiation	GO:0045664	281	0.012
epithelial to mesenchymal transition	GO:0001837	47	0.012
purine ribonucleotide catabolic process	GO:0009154	208	0.012
regulation of nucleoside metabolic process	GO:0009118	130	0.012
coenzyme metabolic process	GO:0006732	52	0.012
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.012
negative regulation of cell development	GO:0010721	169	0.012
maternal placenta development	GO:0001893	20	0.012
regulation of cell cycle process	GO:0010564	160	0.012	Worm
divalent inorganic cation transport	GO:0072511	178	0.012
base excision repair	GO:0006284	9	0.012
regulation of muscle system process	GO:0090257	80	0.012
response to extracellular stimulus	GO:0009991	127	0.012
protein localization to organelle	GO:0033365	185	0.012
regulation of protein modification by small protein conjugation or removal	GO:1903320	57	0.012
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.012
cellular response to hormone stimulus	GO:0032870	150	0.011
negative regulation of nervous system development	GO:0051961	156	0.011
muscle contraction	GO:0006936	101	0.011
regulation of binding	GO:0051098	111	0.011
dna hypermethylation	GO:0044026	3	0.011
inflammatory response	GO:0006954	244	0.011
regulation of kinase activity	GO:0043549	249	0.011
regulation of mitotic cell cycle phase transition	GO:1901990	73	0.011
maintenance of location	GO:0051235	89	0.011
3 utr mediated mrna stabilization	GO:0070935	2	0.011
sequestering of metal ion	GO:0051238	19	0.011
forebrain development	GO:0030900	302	0.011
embryonic organ morphogenesis	GO:0048562	276	0.011
multicellular organismal homeostasis	GO:0048871	164	0.011
striated muscle contraction	GO:0006941	45	0.011
cell division	GO:0051301	120	0.011	Worm
skeletal system development	GO:0001501	356	0.011
respiratory system development	GO:0060541	190	0.010
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.010
response to acid chemical	GO:0001101	111	0.010
cofactor metabolic process	GO:0051186	80	0.010
formation of organ boundary	GO:0010160	1	0.010
purine ribonucleoside catabolic process	GO:0046130	205	0.010
neuron death	GO:0070997	154	0.010
muscle system process	GO:0003012	141	0.010
regulation of system process	GO:0044057	200	0.010
histone h3 k4 methylation	GO:0051568	23	0.010
inorganic cation transmembrane transport	GO:0098662	207	0.010
purine ribonucleotide metabolic process	GO:0009150	290	0.010
negative regulation of rna splicing	GO:0033119	12	0.010	Human

Rnps1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.082
disease of anatomical entity	DOID:7	0.082
central nervous system disease	DOID:331	0.026
peripheral neuropathy	DOID:0060053	0.023
neuropathy	DOID:870	0.023
neurodegenerative disease	DOID:1289	0.015
hereditary sensory neuropathy	DOID:0050548	0.015
disease of cellular proliferation	DOID:14566	0.013

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