| cellular chemical homeostasis | GO:0055082 | 215 | 0.410 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.344 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.308 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.292 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.287 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.274 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.268 | |
| protein catabolic process | GO:0030163 | 221 | 0.224 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.219 | |
| cation homeostasis | GO:0055080 | 212 | 0.219 | |
| dna metabolic process | GO:0006259 | 303 | 0.207 | |
| metal ion homeostasis | GO:0055065 | 189 | 0.207 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.203 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.189 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.177 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.165 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.153 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.152 | |
| neuron apoptotic process | GO:0051402 | 142 | 0.149 | |
| cellular homeostasis | GO:0019725 | 240 | 0.148 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.142 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.135 | |
| regulation of cellular protein catabolic process | GO:1903362 | 61 | 0.126 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.119 | |
| transmembrane transport | GO:0055085 | 412 | 0.118 | |
| organelle assembly | GO:0070925 | 177 | 0.117 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.117 | |
| cell division | GO:0051301 | 120 | 0.117 | |
| neuron death | GO:0070997 | 154 | 0.112 | |
| cytokine production | GO:0001816 | 319 | 0.111 | |
| regulation of defense response | GO:0031347 | 233 | 0.110 | |
| cellular metal ion homeostasis | GO:0006875 | 151 | 0.108 | |
| positive regulation of proteolysis | GO:0045862 | 85 | 0.107 | |
| transition metal ion homeostasis | GO:0055076 | 54 | 0.098 | |
| positive regulation of cellular protein catabolic process | GO:1903364 | 34 | 0.093 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.089 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.085 | |
| regulation of innate immune response | GO:0045088 | 91 | 0.080 | |
| transition metal ion transport | GO:0000041 | 38 | 0.079 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.078 | |
| protein localization to organelle | GO:0033365 | 185 | 0.077 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.074 | |
| inorganic ion transmembrane transport | GO:0098660 | 234 | 0.074 | |
| axonogenesis | GO:0007409 | 274 | 0.073 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.073 | |
| cellular response to transforming growth factor beta stimulus | GO:0071560 | 88 | 0.071 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.069 | |
| protein ubiquitination | GO:0016567 | 171 | 0.068 | |
| developmental maturation | GO:0021700 | 193 | 0.068 | |
| stem cell differentiation | GO:0048863 | 268 | 0.065 | |
| lymphocyte homeostasis | GO:0002260 | 64 | 0.064 | |
| gland development | GO:0048732 | 330 | 0.061 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.058 | |
| negative regulation of neuron death | GO:1901215 | 98 | 0.058 | |
| negative regulation of cell cycle | GO:0045786 | 123 | 0.057 | |
| protein polyubiquitination | GO:0000209 | 33 | 0.055 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.053 | |
| response to oxidative stress | GO:0006979 | 123 | 0.050 | |
| defense response to other organism | GO:0098542 | 197 | 0.049 | |
| cellular response to external stimulus | GO:0071496 | 88 | 0.049 | |
| positive regulation of innate immune response | GO:0045089 | 80 | 0.048 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.048 | |
| regionalization | GO:0003002 | 337 | 0.048 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.047 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.046 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.046 | |
| chromatin modification | GO:0016568 | 187 | 0.044 | |
| chemotaxis | GO:0006935 | 247 | 0.043 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.043 | |
| digestive tract morphogenesis | GO:0048546 | 147 | 0.042 | |
| negative regulation of cell cycle process | GO:0010948 | 69 | 0.042 | |
| rho protein signal transduction | GO:0007266 | 32 | 0.042 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.042 | |
| cell maturation | GO:0048469 | 127 | 0.042 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.042 | |
| amine metabolic process | GO:0009308 | 45 | 0.040 | |
| organelle localization | GO:0051640 | 179 | 0.040 | |
| centrosome duplication | GO:0051298 | 16 | 0.039 | |
| regulation of neuron apoptotic process | GO:0043523 | 122 | 0.039 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.039 | |
| regulation of chromosome organization | GO:0033044 | 83 | 0.039 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.039 | |
| regulation of transforming growth factor beta receptor signaling pathway | GO:0017015 | 43 | 0.038 | |
| cellular transition metal ion homeostasis | GO:0046916 | 32 | 0.038 | |
| response to extracellular stimulus | GO:0009991 | 127 | 0.037 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.037 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.037 | |
| positive regulation of cell development | GO:0010720 | 237 | 0.036 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.035 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.035 | |
| negative regulation of dna dependent dna replication | GO:2000104 | 1 | 0.035 | |
| histone modification | GO:0016570 | 159 | 0.035 | |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.034 | |
| innate immune response | GO:0045087 | 157 | 0.034 | |
| gene silencing | GO:0016458 | 38 | 0.034 | |
| regulation of protein localization | GO:0032880 | 231 | 0.034 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.033 | |
| stem cell development | GO:0048864 | 219 | 0.032 | |
| maintenance of location | GO:0051235 | 89 | 0.032 | |
| regulation of cellular component size | GO:0032535 | 121 | 0.032 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.031 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.031 | |
| meiotic cell cycle process | GO:1903046 | 77 | 0.031 | |
| cellularization | GO:0007349 | 1 | 0.031 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.030 | |
| forebrain development | GO:0030900 | 302 | 0.029 | |
| regulation of neuron death | GO:1901214 | 134 | 0.028 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.027 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.026 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 127 | 0.026 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.026 | |
| microtubule based process | GO:0007017 | 236 | 0.026 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.026 | |
| negative regulation of neuron apoptotic process | GO:0043524 | 92 | 0.025 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.025 | |
| myeloid leukocyte differentiation | GO:0002573 | 119 | 0.024 | |
| appendage development | GO:0048736 | 166 | 0.024 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.024 | |
| multicellular organismal homeostasis | GO:0048871 | 164 | 0.024 | |
| regulation of cell projection organization | GO:0031344 | 206 | 0.024 | |
| skeletal system development | GO:0001501 | 356 | 0.024 | |
| compound eye development | GO:0048749 | 1 | 0.023 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.023 | |
| chromosome segregation | GO:0007059 | 48 | 0.023 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.023 | |
| regulation of cell migration | GO:0030334 | 219 | 0.023 | |
| protein modification by small protein removal | GO:0070646 | 21 | 0.023 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.023 | |
| endocytosis | GO:0006897 | 168 | 0.023 | |
| regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090092 | 112 | 0.023 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.023 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.023 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.022 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.022 | |
| oogenesis | GO:0048477 | 56 | 0.022 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.022 | |
| cognition | GO:0050890 | 149 | 0.022 | |
| leukocyte homeostasis | GO:0001776 | 79 | 0.022 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.022 | |
| cation transport | GO:0006812 | 399 | 0.021 | |
| regulation of inflammatory response | GO:0050727 | 147 | 0.021 | |
| negative regulation of immune system process | GO:0002683 | 209 | 0.021 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.021 | |
| synaptic transmission | GO:0007268 | 329 | 0.021 | |
| regulation of ossification | GO:0030278 | 112 | 0.021 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.021 | |
| defense response to bacterium | GO:0042742 | 119 | 0.020 | |
| positive regulation of secretion | GO:0051047 | 130 | 0.020 | |
| iron ion homeostasis | GO:0055072 | 36 | 0.020 | |
| response to radiation | GO:0009314 | 165 | 0.020 | |
| phagocytosis | GO:0006909 | 66 | 0.020 | |
| glycerolipid biosynthetic process | GO:0045017 | 50 | 0.020 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.020 | |
| digestive system development | GO:0055123 | 200 | 0.020 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.019 | |
| response to nutrient levels | GO:0031667 | 109 | 0.019 | |
| organophosphate biosynthetic process | GO:0090407 | 122 | 0.019 | |
| regulation of ion transport | GO:0043269 | 215 | 0.018 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.018 | |
| regulation of protein transport | GO:0051223 | 163 | 0.018 | |
| lung development | GO:0030324 | 164 | 0.018 | |
| erk1 and erk2 cascade | GO:0070371 | 77 | 0.018 | |
| female gamete generation | GO:0007292 | 74 | 0.018 | |
| negative regulation of growth | GO:0045926 | 99 | 0.018 | |
| wound healing | GO:0042060 | 157 | 0.018 | |
| germ cell development | GO:0007281 | 185 | 0.018 | |
| exocytosis | GO:0006887 | 121 | 0.018 | |
| snrna 3 end processing | GO:0034472 | 1 | 0.018 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.018 | |
| production of molecular mediator of immune response | GO:0002440 | 103 | 0.018 | |
| rna polymerase ii transcriptional preinitiation complex assembly | GO:0051123 | 3 | 0.018 | |
| response to growth factor | GO:0070848 | 198 | 0.017 | |
| rna 3 end processing | GO:0031123 | 20 | 0.017 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 85 | 0.017 | |
| positive regulation of cell motility | GO:2000147 | 116 | 0.017 | |
| nuclear division | GO:0000280 | 158 | 0.017 | |
| rna catabolic process | GO:0006401 | 29 | 0.017 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.017 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.017 | |
| mapk cascade | GO:0000165 | 281 | 0.017 | |
| negative regulation of synapse assembly | GO:0051964 | 3 | 0.017 | |
| gastrulation | GO:0007369 | 116 | 0.017 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.016 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.016 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.016 | |
| positive regulation of cytokine production | GO:0001819 | 174 | 0.016 | |
| ossification | GO:0001503 | 216 | 0.016 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.016 | |
| negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090101 | 61 | 0.016 | |
| cellular response to extracellular stimulus | GO:0031668 | 81 | 0.016 | |
| establishment of organelle localization | GO:0051656 | 122 | 0.016 | |
| regulation of erk1 and erk2 cascade | GO:0070372 | 71 | 0.015 | |
| ncrna 3 end processing | GO:0043628 | 2 | 0.015 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.015 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.015 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.015 | |
| blastocyst formation | GO:0001825 | 33 | 0.015 | |
| chromatin organization | GO:0006325 | 206 | 0.015 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 81 | 0.015 | |
| internal protein amino acid acetylation | GO:0006475 | 42 | 0.015 | |
| neuron projection guidance | GO:0097485 | 141 | 0.015 | |
| odontogenesis | GO:0042476 | 78 | 0.014 | |
| peptidyl lysine modification | GO:0018205 | 77 | 0.014 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.014 | |
| trophectodermal cell differentiation | GO:0001829 | 21 | 0.014 | |
| transforming growth factor beta receptor signaling pathway | GO:0007179 | 71 | 0.014 | |
| antibacterial peptide production | GO:0002778 | 2 | 0.014 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.014 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.014 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.014 | |
| regulation of neuron projection development | GO:0010975 | 169 | 0.014 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.014 | |
| mitotic nuclear division | GO:0007067 | 48 | 0.014 | |
| muscle system process | GO:0003012 | 141 | 0.014 | |
| myeloid leukocyte activation | GO:0002274 | 83 | 0.014 | |
| developmental growth involved in morphogenesis | GO:0060560 | 138 | 0.014 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.014 | |
| regulation of epithelial cell proliferation | GO:0050678 | 141 | 0.014 | |
| epithelial cell development | GO:0002064 | 159 | 0.014 | |
| stem cell maintenance | GO:0019827 | 130 | 0.014 | |
| positive regulation of cell migration | GO:0030335 | 109 | 0.014 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 58 | 0.013 | |
| anatomical structure homeostasis | GO:0060249 | 145 | 0.013 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.013 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.013 | |
| protein acylation | GO:0043543 | 64 | 0.013 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.013 | |
| regulation of secretion | GO:0051046 | 274 | 0.013 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.013 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.013 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.013 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.013 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.013 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.013 | |
| limb morphogenesis | GO:0035108 | 149 | 0.013 | |
| ribonucleoside monophosphate catabolic process | GO:0009158 | 57 | 0.013 | |
| response to steroid hormone | GO:0048545 | 56 | 0.013 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.013 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.013 | |
| positive regulation of nervous system development | GO:0051962 | 221 | 0.013 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.013 | |
| protein deubiquitination | GO:0016579 | 19 | 0.012 | |
| regulation of histone modification | GO:0031056 | 56 | 0.012 | |
| positive regulation of cell projection organization | GO:0031346 | 95 | 0.012 | |
| oocyte axis specification | GO:0007309 | 2 | 0.012 | |
| body fluid secretion | GO:0007589 | 53 | 0.012 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.012 | |
| metencephalon development | GO:0022037 | 89 | 0.012 | |
| maintenance of location in cell | GO:0051651 | 24 | 0.012 | |
| tube formation | GO:0035148 | 140 | 0.012 | |
| positive regulation of mitotic sister chromatid separation | GO:1901970 | 2 | 0.012 | |
| covalent chromatin modification | GO:0016569 | 163 | 0.012 | |
| positive regulation of transforming growth factor beta2 production | GO:0032915 | 2 | 0.012 | |
| embryonic appendage morphogenesis | GO:0035113 | 126 | 0.012 | |
| establishment or maintenance of polarity of embryonic epithelium | GO:0016332 | 1 | 0.012 | |
| osteoclast differentiation | GO:0030316 | 62 | 0.012 | |
| digestive tract development | GO:0048565 | 190 | 0.012 | |
| positive regulation of protein catabolic process | GO:0045732 | 60 | 0.012 | |
| regulation of osteoblast differentiation | GO:0045667 | 67 | 0.012 | |
| asymmetric neuroblast division | GO:0055059 | 1 | 0.012 | |
| organic hydroxy compound metabolic process | GO:1901615 | 203 | 0.011 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.011 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.011 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.011 | |
| respiratory system development | GO:0060541 | 190 | 0.011 | |
| positive regulation of defense response | GO:0031349 | 124 | 0.011 | |
| regulation of chromatin modification | GO:1903308 | 57 | 0.011 | |
| intra s dna damage checkpoint | GO:0031573 | 4 | 0.011 | |
| regulation of nucleoside metabolic process | GO:0009118 | 130 | 0.011 | |
| blood circulation | GO:0008015 | 195 | 0.011 | |
| translation | GO:0006412 | 93 | 0.011 | |
| appendage morphogenesis | GO:0035107 | 149 | 0.011 | |
| negative regulation of dna replication | GO:0008156 | 4 | 0.011 | |
| dna integrity checkpoint | GO:0031570 | 28 | 0.011 | |
| regulation of body fluid levels | GO:0050878 | 162 | 0.011 | |
| cellular component assembly involved in morphogenesis | GO:0010927 | 139 | 0.011 | |
| phosphatidylinositol biosynthetic process | GO:0006661 | 15 | 0.011 | |
| mammary gland epithelial cell proliferation | GO:0033598 | 24 | 0.011 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 80 | 0.011 | |
| regulation of histone acetylation | GO:0035065 | 19 | 0.011 | |
| transforming growth factor beta2 production | GO:0032906 | 2 | 0.011 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.011 | |
| response to molecule of bacterial origin | GO:0002237 | 143 | 0.011 | |
| defense response to gram positive bacterium | GO:0050830 | 50 | 0.011 | |
| learning or memory | GO:0007611 | 148 | 0.011 | |
| rna processing | GO:0006396 | 105 | 0.011 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.011 | |
| intrinsic apoptotic signaling pathway in response to dna damage | GO:0008630 | 57 | 0.011 | |
| response to lipopolysaccharide | GO:0032496 | 128 | 0.011 | |
| response to transition metal nanoparticle | GO:1990267 | 11 | 0.011 | |
| dna repair | GO:0006281 | 107 | 0.011 | |
| respiratory tube development | GO:0030323 | 167 | 0.011 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 73 | 0.011 | |
| female gonad development | GO:0008585 | 71 | 0.011 | |
| positive regulation of growth | GO:0045927 | 104 | 0.010 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.010 | |
| response to light stimulus | GO:0009416 | 135 | 0.010 | |
| negative regulation of cellular response to growth factor stimulus | GO:0090288 | 46 | 0.010 | |
| connective tissue development | GO:0061448 | 179 | 0.010 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.010 | |
| mrna catabolic process | GO:0006402 | 22 | 0.010 | |
| calcium ion homeostasis | GO:0055074 | 127 | 0.010 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.010 | |
| divalent inorganic cation homeostasis | GO:0072507 | 138 | 0.010 | |
| zinc ion transmembrane transport | GO:0071577 | 10 | 0.010 | |
