IMP: Integrative Multi-species Prediction

Mus musculus

58 known processes

Zswim2

zinc finger, SWIM domain containing 2

(Aliases: 4933437F18Rik,1700025P14Rik,MEX)

Entrez: 71861
Ensembl: ENSMUSG00000034552
UniProtKB: Q0VB10
UniProtKB: Q9D9X6

Process Predictions
Disease Predictions

Zswim2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
male gamete generation	GO:0048232	285	0.042
transmembrane transport	GO:0055085	412	0.036
ion transmembrane transport	GO:0034220	361	0.036
spermatid differentiation	GO:0048515	115	0.033
carbohydrate metabolic process	GO:0005975	230	0.032
spermatid development	GO:0007286	108	0.032
inorganic ion transmembrane transport	GO:0098660	234	0.032
inorganic cation transmembrane transport	GO:0098662	207	0.029
microtubule based process	GO:0007017	236	0.029
macromolecule catabolic process	GO:0009057	281	0.028
reactive nitrogen species metabolic process	GO:2001057	0	0.028
regulation of cellular ketone metabolic process	GO:0010565	66	0.028
sensory perception	GO:0007600	245	0.028
regulation of organelle organization	GO:0033043	289	0.027
organic hydroxy compound metabolic process	GO:1901615	203	0.026
peptidyl amino acid modification	GO:0018193	336	0.026
fertilization	GO:0009566	127	0.025
germ cell development	GO:0007281	185	0.025
regulation of cellular amine metabolic process	GO:0033238	20	0.024
organelle assembly	GO:0070925	177	0.024
cellular ketone metabolic process	GO:0042180	84	0.024
regulation of cell motility	GO:2000145	236	0.023
response to organic cyclic compound	GO:0014070	198	0.022
protein catabolic process	GO:0030163	221	0.022
synaptic transmission	GO:0007268	329	0.022
cytoplasmic transport	GO:0016482	234	0.022
organic anion transport	GO:0015711	137	0.021
regulation of secretion	GO:0051046	274	0.021
spermatogenesis	GO:0007283	284	0.021
negative regulation of protein metabolic process	GO:0051248	282	0.021
negative regulation of cellular protein metabolic process	GO:0032269	247	0.020
immune effector process	GO:0002252	321	0.020
anion transport	GO:0006820	177	0.020
cellular amino acid metabolic process	GO:0006520	103	0.020
reactive oxygen species biosynthetic process	GO:1903409	8	0.020
sulfur compound metabolic process	GO:0006790	100	0.019
homeostasis of number of cells	GO:0048872	210	0.019
negative regulation of molecular function	GO:0044092	258	0.018
cellular amine metabolic process	GO:0044106	44	0.018
response to organonitrogen compound	GO:0010243	246	0.018
cellular chemical homeostasis	GO:0055082	215	0.018
cellular component assembly involved in morphogenesis	GO:0010927	139	0.018
cation transport	GO:0006812	399	0.018
cellular lipid metabolic process	GO:0044255	323	0.017
positive regulation of cellular amine metabolic process	GO:0033240	5	0.016
cellular homeostasis	GO:0019725	240	0.016
negative regulation of cellular component organization	GO:0051129	194	0.016
steroid metabolic process	GO:0008202	119	0.016
cation transmembrane transport	GO:0098655	266	0.016
mapk cascade	GO:0000165	281	0.015
small molecule biosynthetic process	GO:0044283	132	0.015
nuclear division	GO:0000280	158	0.015
organonitrogen compound biosynthetic process	GO:1901566	192	0.015
cellular ion homeostasis	GO:0006873	165	0.015
regulation of proteolysis	GO:0030162	164	0.015
nuclear transport	GO:0051169	139	0.015
multi multicellular organism process	GO:0044706	109	0.015
regulation of system process	GO:0044057	200	0.015
sperm motility	GO:0030317	47	0.015
cellular response to extracellular stimulus	GO:0031668	81	0.014
nucleocytoplasmic transport	GO:0006913	139	0.014
microtubule cytoskeleton organization	GO:0000226	157	0.014
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.014
sodium ion transport	GO:0006814	73	0.014
amine metabolic process	GO:0009308	45	0.014
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.014
urogenital system development	GO:0001655	261	0.014
maintenance of location	GO:0051235	89	0.014
mucopolysaccharide metabolic process	GO:1903510	25	0.014
organelle fission	GO:0048285	170	0.014
stem cell differentiation	GO:0048863	268	0.014
regulation of mapk cascade	GO:0043408	248	0.013
alcohol metabolic process	GO:0006066	116	0.013
multicellular organism growth	GO:0035264	161	0.013
response to growth factor	GO:0070848	198	0.013
response to testosterone	GO:0033574	3	0.013
regulation of secretion by cell	GO:1903530	249	0.013
protein targeting	GO:0006605	143	0.013
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.013
apoptotic signaling pathway	GO:0097190	306	0.013
exocytosis	GO:0006887	121	0.013
lipid localization	GO:0010876	126	0.013
organophosphate biosynthetic process	GO:0090407	122	0.013
regulation of intracellular transport	GO:0032386	159	0.013
striated muscle tissue development	GO:0014706	293	0.013
carbohydrate derivative biosynthetic process	GO:1901137	183	0.013
cellular response to external stimulus	GO:0071496	88	0.013
regulation of ion transmembrane transport	GO:0034765	119	0.013
organic acid transport	GO:0015849	101	0.012
glycoprotein metabolic process	GO:0009100	116	0.012
cellular protein complex assembly	GO:0043623	116	0.012
somatotropin secreting cell differentiation	GO:0060126	4	0.012
positive regulation of apoptotic process	GO:0043065	217	0.012
nitrogen compound transport	GO:0071705	271	0.012
cellular carbohydrate metabolic process	GO:0044262	119	0.012
glucose homeostasis	GO:0042593	128	0.012
protein ubiquitination	GO:0016567	171	0.012
smoothened signaling pathway	GO:0007224	105	0.012
fat cell differentiation	GO:0045444	160	0.012
meiotic cell cycle	GO:0051321	122	0.012
positive regulation of protein modification process	GO:0031401	299	0.012
proteoglycan metabolic process	GO:0006029	38	0.012
reactive oxygen species metabolic process	GO:0072593	84	0.012
intracellular protein transport	GO:0006886	204	0.012
lymphocyte mediated immunity	GO:0002449	139	0.012
meiotic nuclear division	GO:0007126	115	0.012
hexose metabolic process	GO:0019318	98	0.012
protein localization to organelle	GO:0033365	185	0.011
negative regulation of intracellular signal transduction	GO:1902532	167	0.011
response to extracellular stimulus	GO:0009991	127	0.011
regulation of cytoplasmic transport	GO:1903649	112	0.011
cellular response to organonitrogen compound	GO:0071417	145	0.011
protein modification by small protein conjugation	GO:0032446	187	0.011
triglyceride metabolic process	GO:0006641	51	0.011
cell substrate adhesion	GO:0031589	130	0.011
defense response to other organism	GO:0098542	197	0.011
regulation of hormone levels	GO:0010817	211	0.011
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.011
alcohol biosynthetic process	GO:0046165	43	0.011
regulation of intracellular protein transport	GO:0033157	82	0.011
protein localization to nucleus	GO:0034504	121	0.011
protein modification by small protein conjugation or removal	GO:0070647	207	0.011
microtubule based movement	GO:0007018	84	0.011
regulation of cell adhesion	GO:0030155	154	0.011
regulation of reactive oxygen species biosynthetic process	GO:1903426	2	0.011
carbohydrate homeostasis	GO:0033500	128	0.011
lipid biosynthetic process	GO:0008610	179	0.011
angiogenesis	GO:0001525	201	0.011
action potential	GO:0001508	78	0.011
oocyte construction	GO:0007308	2	0.011
negative regulation of protein modification process	GO:0031400	163	0.011
amino acid transport	GO:0006865	61	0.011
respiratory system development	GO:0060541	190	0.010
positive regulation of cilium movement	GO:0003353	1	0.010
cognition	GO:0050890	149	0.010
positive regulation of cell development	GO:0010720	237	0.010
chromatin organization	GO:0006325	206	0.010
mitochondrion organization	GO:0007005	134	0.010
regulation of protein catabolic process	GO:0042176	108	0.010
organelle localization	GO:0051640	179	0.010
oxidation reduction process	GO:0055114	342	0.010
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.010
cell growth	GO:0016049	130	0.010
cellular metal ion homeostasis	GO:0006875	151	0.010
response to inorganic substance	GO:0010035	96	0.010
mesodermal cell migration	GO:0008078	4	0.010
protein acylation	GO:0043543	64	0.010
defense response to bacterium	GO:0042742	119	0.010
response to peptide hormone	GO:0043434	127	0.010
protein import	GO:0017038	101	0.010

Zswim2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.018
disease of anatomical entity	DOID:7	0.018
eye and adnexa disease	DOID:1492	0.010
eye disease	DOID:5614	0.010
sensory system disease	DOID:0050155	0.010

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