Mus musculus

50 known processes

Gpx2

glutathione peroxidase 2

(Aliases: GPx-GI,GSHPx-GI,GSHPx-2)

Gpx2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxidation reduction processGO:00551143420.109
cell junction maintenanceGO:003433140.102
protein localization to membraneGO:00726571080.063
apoptotic signaling pathwayGO:00971903060.060
Mouse
protein maturationGO:00516041760.055
regulation of response to woundingGO:19030341890.051
organelle localizationGO:00516401790.050
protein processingGO:00164851630.047
negative regulation of cellular component organizationGO:00511291940.047
epithelial cell developmentGO:00020641590.046
Mouse
regulation of proteolysisGO:00301621640.045
regulation of cell motilityGO:20001452360.044
transmembrane transportGO:00550854120.043
positive regulation of cell deathGO:00109422240.043
fertilizationGO:00095661270.042
cell type specific apoptotic processGO:00972852680.041
Mouse
regulation of organelle organizationGO:00330432890.041
positive regulation of apoptotic processGO:00430652170.041
striated muscle tissue developmentGO:00147062930.040
Mouse
oocyte constructionGO:000730820.040
regulation of cellular amino acid metabolic processGO:000652150.040
endomembrane system organizationGO:00102561470.039
muscle tissue developmentGO:00605373080.039
Mouse
multicellular organismal water homeostasisGO:0050891230.038
positive regulation of programmed cell deathGO:00430682180.038
membrane organizationGO:00610242450.037
establishment of organelle localizationGO:00516561220.037
ras protein signal transductionGO:0007265770.037
cellular amine metabolic processGO:0044106440.036
regulation of cell cycle processGO:00105641600.036
regulation of cell migrationGO:00303342190.035
regulation of transferase activityGO:00513382630.035
regulation of apoptotic signaling pathwayGO:20012331970.034
Mouse
regulation of protein processingGO:0070613960.034
cytokine productionGO:00018163190.034
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.033
cellular response to dna damage stimulusGO:00069742070.033
small gtpase mediated signal transductionGO:0007264970.032
regulation of endopeptidase activityGO:0052548890.032
response to organic cyclic compoundGO:00140701980.031
regulation of cytokine productionGO:00018172660.031
reactive oxygen species metabolic processGO:0072593840.030
Mouse
amine metabolic processGO:0009308450.030
regulation of peptidase activityGO:0052547960.030
cellular amino acid metabolic processGO:00065201030.030
negative regulation of molecular functionGO:00440922580.029
regulation of cellular ketone metabolic processGO:0010565660.029
protein modification by small protein conjugation or removalGO:00706472070.028
regulation of neuron differentiationGO:00456642810.028
cellular component assembly involved in morphogenesisGO:00109271390.028
adherens junction maintenanceGO:003433410.028
keratinocyte differentiationGO:0030216480.028
dephosphorylationGO:00163111290.028
cellular lipid metabolic processGO:00442553230.028
Mouse
negative regulation of proteolysisGO:0045861740.028
regulation of mapk cascadeGO:00434082480.027
lipid homeostasisGO:0055088630.027
anatomical structure homeostasisGO:00602491450.027
negative regulation of cellular protein metabolic processGO:00322692470.027
immune response activating signal transductionGO:00027571160.026
positive regulation of mapk cascadeGO:00434101700.026
cellularizationGO:000734910.026
cellular macromolecule catabolic processGO:00442652060.025
negative regulation of organelle organizationGO:0010639900.025
regulation of body fluid levelsGO:00508781620.025
symbiosis encompassing mutualism through parasitismGO:0044403830.024
negative regulation of cell proliferationGO:00082852960.024
regulation of cell cycleGO:00517262810.024
negative regulation of cellular amine metabolic processGO:003323910.024
sensory perception of soundGO:0007605970.024
Mouse
interspecies interaction between organismsGO:0044419830.024
nucleobase containing small molecule metabolic processGO:00550863520.024
response to lipopolysaccharideGO:00324961280.023
negative regulation of synapse assemblyGO:005196430.023
positive regulation of macrophage derived foam cell differentiationGO:001074440.023
microtubule based processGO:00070172360.023
compound eye developmentGO:004874910.023
regulation of protein maturationGO:1903317960.023
regulation of membrane potentialGO:00423911920.023
spermatogenesisGO:00072832840.023
regulation of defense responseGO:00313472330.022
negative regulation of protein metabolic processGO:00512482820.022
establishment of protein localization to membraneGO:0090150540.022
plasma membrane organizationGO:0007009900.022
nucleoside phosphate metabolic processGO:00067533380.022
meiotic cell cycleGO:00513211220.022
mesendoderm migrationGO:009013310.022
protein localization to plasma membraneGO:0072659570.021
establishment or maintenance of cytoskeleton polarityGO:003095220.021
modification dependent protein catabolic processGO:00199411330.021
multicellular organismal signalingGO:0035637910.021
regulation of protein kinase activityGO:00458592320.021
aromatic compound catabolic processGO:00194392860.020
wound healingGO:00420601570.020
Mouse
posttranscriptional regulation of gene expressionGO:00106081550.020
organophosphate catabolic processGO:00464342320.020
response to organonitrogen compoundGO:00102432460.020
purine containing compound metabolic processGO:00725213110.020
positive regulation of vesicle fusionGO:003134020.020
angiogenesisGO:00015252010.020
Mouse
macromolecule catabolic processGO:00090572810.020
muscle cell differentiationGO:00426922610.019
Mouse
cellular nitrogen compound catabolic processGO:00442702800.019
detection of external stimulusGO:0009581610.019
proteolysis involved in cellular protein catabolic processGO:00516031470.019
negative regulation of bone trabecula formationGO:190015510.019
organic hydroxy compound transportGO:0015850930.019
regulation of kinase activityGO:00435492490.019
positive regulation of protein phosphorylationGO:00019342420.019
sensory perceptionGO:00076002450.019
Mouse
positive regulation of cell activationGO:00508671580.019
response to inorganic substanceGO:0010035960.019
Mouse
heart processGO:0003015940.019
Mouse
organic hydroxy compound metabolic processGO:19016152030.019
nk t cell proliferationGO:000186620.018
cytoplasmic transportGO:00164822340.018
protein ubiquitinationGO:00165671710.018
cell growthGO:00160491300.018
steroid metabolic processGO:00082021190.018
microtubule cytoskeleton organizationGO:00002261570.018
response to radiationGO:00093141650.018
Mouse
negative regulation of protein maturationGO:1903318790.018
cellular response to epidermal growth factor stimulusGO:007136440.018
glucose homeostasisGO:00425931280.018
regulation of transmembrane transportGO:00347621280.018
regulation of establishment of protein localizationGO:00702011810.018
regulation of protein serine threonine kinase activityGO:00719001570.018
formation of organ boundaryGO:001016010.018
lymphocyte proliferationGO:00466511640.018
intrinsic apoptotic signaling pathwayGO:00971931320.017
Mouse
glycoprotein biosynthetic processGO:0009101890.017
regulation of ion transmembrane transportGO:00347651190.017
alcohol metabolic processGO:00060661160.017
protein oligomerizationGO:0051259670.017
oocyte axis specificationGO:000730920.017
lipoprotein metabolic processGO:0042157430.017
cellular response to oxidative stressGO:0034599760.017
Yeast Mouse
regulation of cell projection organizationGO:00313442060.017
regulation of hydrolase activityGO:00513362460.017
glycosyl compound metabolic processGO:19016572460.017
regulation of cellular response to stressGO:00801351590.017
Mouse
transmission of nerve impulseGO:0019226760.017
detection of stimulusGO:0051606840.017
regulation of nuclear divisionGO:0051783560.017
neuron apoptotic processGO:00514021420.017
Mouse
inorganic cation transmembrane transportGO:00986622070.017
urogenital system developmentGO:00016552610.016
mapk cascadeGO:00001652810.016
positive regulation of protein kinase activityGO:00458601440.016
cellular protein catabolic processGO:00442571550.016
vasodilationGO:0042311280.016
Mouse
negative regulation of protein phosphorylationGO:00019331260.016
organic cyclic compound catabolic processGO:19013612950.016
cation transportGO:00068123990.016
tissue homeostasisGO:00018941150.016
establishment of vesicle localizationGO:0051650810.016
cation transmembrane transportGO:00986552660.016
positive regulation of protein modification processGO:00314012990.016
negative regulation of peptidase activityGO:0010466460.016
regulation of protein localizationGO:00328802310.016
modification dependent macromolecule catabolic processGO:00436321330.016
skeletal muscle tissue regenerationGO:0043403200.015
Mouse
regulation of cell activationGO:00508652890.015
immune response regulating signaling pathwayGO:00027641250.015
purine containing compound catabolic processGO:00725232130.015
stem cell developmentGO:00488642190.015
leukocyte proliferationGO:00706611720.015
rap protein signal transductionGO:003248630.015
coagulationGO:0050817780.015
negative regulation of cell activationGO:00508661110.015
proteasomal protein catabolic processGO:0010498980.015
germ cell developmentGO:00072811850.015
action potentialGO:0001508780.015
positive regulation of cellular amino acid metabolic processGO:004576430.015
g protein coupled acetylcholine receptor signaling pathwayGO:000721340.015
skeletal muscle organ developmentGO:00605381630.015
Mouse
negative regulation of defense responseGO:0031348770.015
multicellular organismal homeostasisGO:00488711640.015
glycosyl compound catabolic processGO:19016582060.015
negative regulation of protein processingGO:0010955790.015
blastocyst developmentGO:0001824800.015
exocytosisGO:00068871210.014
retrograde transport endosome to golgiGO:004214720.014
protein catabolic processGO:00301632210.014
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631190.014
Mouse
regulation of cellular amine metabolic processGO:0033238200.014
negative regulation of endopeptidase activityGO:0010951440.014
negative regulation of protein modification processGO:00314001630.014
positive regulation of kinase activityGO:00336741550.014
peptidyl amino acid modificationGO:00181933360.014
natural killer cell proliferationGO:000178730.014
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.014
regulation of cysteine type endopeptidase activityGO:2000116650.014
skin developmentGO:00435882200.014
heterocycle catabolic processGO:00467002800.014
regulation of synaptic plasticityGO:0048167870.014
inclusion body assemblyGO:007084130.014
chromatin organizationGO:00063252060.014
rho protein signal transductionGO:0007266320.014
single organismal cell cell adhesionGO:00163371310.014
purine nucleoside catabolic processGO:00061522050.014
epinephrine secretionGO:004824210.014
blood vessel morphogenesisGO:00485142850.013
Mouse
purine nucleoside metabolic processGO:00422782410.013
regulation of intracellular transportGO:00323861590.013
positive regulation of cytokine productionGO:00018191740.013
epithelial cell migrationGO:0010631630.013
Mouse
negative regulation of phosphorus metabolic processGO:00105631840.013
satellite cell activation involved in skeletal muscle regenerationGO:001490130.013
protein modification by small protein conjugationGO:00324461870.013
glycoprotein metabolic processGO:00091001160.013
regulation of cell cycle phase transitionGO:1901987770.013
av node cell to bundle of his cell communicationGO:008606720.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.013
regulation of secretionGO:00510462740.013
cholesterol metabolic processGO:0008203560.013
protein oxidationGO:001815820.013
Mouse
developmental growth involved in morphogenesisGO:00605601380.013
single fertilizationGO:0007338820.013
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.013
male gamete generationGO:00482322850.013
regulation of protein transportGO:00512231630.013
regulation of cell divisionGO:0051302760.013
negative regulation of cellular amino acid metabolic processGO:004576300.013
regulation of satellite cell activation involved in skeletal muscle regenerationGO:001471730.013
chromosome segregationGO:0007059480.013
innate immune response in mucosaGO:000222730.013
negative regulation of hydrolase activityGO:0051346710.012
ribonucleoside catabolic processGO:00424542060.012
regulation of ion transportGO:00432692150.012
neuronal action potentialGO:0019228540.012
membrane depolarizationGO:0051899640.012
intracellular mrna localizationGO:000829840.012
organelle fissionGO:00482851700.012
cellular ketone metabolic processGO:0042180840.012
calcium ion dependent exocytosisGO:0017156350.012
immune effector processGO:00022523210.012
regulation of keratinocyte differentiationGO:0045616110.012
positive regulation of protein serine threonine kinase activityGO:00719021060.012
cellular response to lipidGO:00713961450.012
oocyte anterior posterior axis specificationGO:000731420.012
regulation of mitotic cell cycle phase transitionGO:1901990730.012
negative regulation of cell sizeGO:004579230.012
fatty acid metabolic processGO:00066311210.012
regulation of cytoskeleton organizationGO:00514931220.012
regulation of protein catabolic processGO:00421761080.012
muscle cell developmentGO:00550011330.012
Mouse
purine ribonucleotide catabolic processGO:00091542080.012
positive regulation of organelle organizationGO:00106381280.012
signal transduction involved in cell cycle checkpointGO:007239530.012
regulation of endocytosisGO:0030100690.012
sterol homeostasisGO:0055092450.012
sterol metabolic processGO:0016125580.012
negative regulation of dendritic spine developmentGO:006100030.012
ossificationGO:00015032160.012
regulation of antigen receptor mediated signaling pathwayGO:0050854290.012
nucleoside metabolic processGO:00091162460.011
response to oxidative stressGO:00069791230.011
Yeast Mouse
negative regulation of multi organism processGO:0043901680.011
regulation of exit from mitosisGO:000709610.011
extracellular structure organizationGO:00430621480.011
purine nucleoside triphosphate catabolic processGO:00091462030.011
establishment or maintenance of cell polarityGO:0007163860.011
cellular response to growth factor stimulusGO:00713631970.011
camera type eye developmentGO:00430102660.011
epidermis developmentGO:00085441870.011
foramen ovale closureGO:003592210.011
regulation of multi organism processGO:00439001110.011
ion transmembrane transportGO:00342203610.011
nucleoside phosphate catabolic processGO:19012922220.011
negative regulation of response to woundingGO:1903035770.011
nucleoside triphosphate catabolic processGO:00091432050.011
negative regulation of keratinocyte differentiationGO:004561740.011
regulation of ras protein signal transductionGO:00465781140.011
sensory perception of mechanical stimulusGO:00509541070.011
Mouse
humoral immune responseGO:0006959570.011
myoblast proliferationGO:0051450110.011
Mouse
regulation of ovulationGO:006027830.011
cellular response to cadmium ionGO:007127630.011
regulation of vesicle mediated transportGO:00606271390.011
directional locomotionGO:003305830.011
lung developmentGO:00303241640.011
purine ribonucleoside triphosphate catabolic processGO:00092071990.011
rab protein signal transductionGO:003248210.011
cellular response to amino acid stimulusGO:0071230290.011
regulation of keratinocyte proliferationGO:0010837150.011
regulation of organ morphogenesisGO:20000271440.011
retina homeostasisGO:0001895230.011
tissue migrationGO:0090130680.011
Mouse
peptide metabolic processGO:0006518460.011
innate immune responseGO:00450871570.011
response to estrogenGO:0043627240.011
positive regulation of defense responseGO:00313491240.011
ribonucleoside metabolic processGO:00091192450.011
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.011
fucosylationGO:003606590.011
ubiquitin dependent protein catabolic processGO:00065111290.010
macromolecule methylationGO:00434141200.010
retina development in camera type eyeGO:00600411190.010
positive regulation of intracellular transportGO:0032388700.010
negative regulation of cell developmentGO:00107211690.010
cell divisionGO:00513011200.010
protein homooligomerizationGO:0051260430.010
nuclear divisionGO:00002801580.010
dna metabolic processGO:00062593030.010
sensory organ morphogenesisGO:00905962420.010
mitotic cell cycleGO:00002781950.010
organ or tissue specific immune responseGO:0002251130.010
regulation of renin secretion into blood streamGO:190013340.010
purine ribonucleoside catabolic processGO:00461302050.010
protein secretionGO:00093061110.010
negative regulation of cytoskeleton organizationGO:0051494360.010
ribonucleoside triphosphate metabolic processGO:00091992200.010
molting cycleGO:0042303900.010
cell cell junction organizationGO:0045216720.010
wnt signaling pathwayGO:00160551880.010
ribonucleoside triphosphate catabolic processGO:00092031990.010

Gpx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.027
sensory system diseaseDOID:005015500.027
nervous system diseaseDOID:86300.027
eye diseaseDOID:561400.021
eye and adnexa diseaseDOID:149200.021
inherited metabolic disorderDOID:65500.016
disease of metabolismDOID:001466700.016
retinal diseaseDOID:567900.012
retinal degenerationDOID:846600.012
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011