IMP: Integrative Multi-species Prediction

Mus musculus

8 known processes

Mst1r

macrophage stimulating 1 receptor (c-met-related tyrosine kinase)

(Aliases: CD136,CDw136,Ron,PTK8,STK,Fv-2,Fv2)

Ensembl: ENSMUSG00000032584
Entrez: 19882
UniProtKB: Q62190

Process Predictions
Disease Predictions

Mst1r biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
negative regulation of immune system process	GO:0002683	209	0.454	Mouse
ras protein signal transduction	GO:0007265	77	0.402
immune effector process	GO:0002252	321	0.399
positive regulation of apoptotic process	GO:0043065	217	0.388
organic hydroxy compound metabolic process	GO:1901615	203	0.378
small gtpase mediated signal transduction	GO:0007264	97	0.369
organic cyclic compound catabolic process	GO:1901361	295	0.285
developmental growth involved in morphogenesis	GO:0060560	138	0.241	Mouse
nitrogen compound transport	GO:0071705	271	0.239
regulation of cytokine production	GO:0001817	266	0.239	Mouse
regulation of hydrolase activity	GO:0051336	246	0.234
kidney epithelium development	GO:0072073	121	0.232
purine containing compound metabolic process	GO:0072521	311	0.230
germ cell development	GO:0007281	185	0.221
renal system development	GO:0072001	225	0.221
myeloid cell differentiation	GO:0030099	233	0.221
aromatic compound catabolic process	GO:0019439	286	0.220
heterocycle catabolic process	GO:0046700	280	0.217
t cell activation	GO:0042110	289	0.216
regulation of ras gtpase activity	GO:0032318	88	0.214
nucleobase containing small molecule metabolic process	GO:0055086	352	0.214
regulation of ras protein signal transduction	GO:0046578	114	0.211
urogenital system development	GO:0001655	261	0.210
inflammatory response	GO:0006954	244	0.210	Mouse
regulation of mapk cascade	GO:0043408	248	0.209	Human Mouse
developmental maturation	GO:0021700	193	0.208
positive regulation of protein modification process	GO:0031401	299	0.204	Human Mouse
regulation of cellular catabolic process	GO:0031329	242	0.203
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.203
ion transmembrane transport	GO:0034220	361	0.202
rho protein signal transduction	GO:0007266	32	0.201
epithelial cell proliferation	GO:0050673	174	0.197
regulation of response to wounding	GO:1903034	189	0.195	Mouse
sensory organ morphogenesis	GO:0090596	242	0.193
cell type specific apoptotic process	GO:0097285	268	0.192	Mouse
apoptotic signaling pathway	GO:0097190	306	0.192
purine ribonucleotide catabolic process	GO:0009154	208	0.191
lung development	GO:0030324	164	0.190
gland development	GO:0048732	330	0.189	Mouse
nucleoside phosphate catabolic process	GO:1901292	222	0.189
morphogenesis of a branching structure	GO:0001763	203	0.188	Mouse
inorganic ion transmembrane transport	GO:0098660	234	0.188
mesonephric epithelium development	GO:0072163	94	0.187
branching involved in ureteric bud morphogenesis	GO:0001658	56	0.184
nucleoside phosphate metabolic process	GO:0006753	338	0.183
ribonucleotide metabolic process	GO:0009259	291	0.181
digestive tract development	GO:0048565	190	0.171
alcohol metabolic process	GO:0006066	116	0.171
morphogenesis of embryonic epithelium	GO:0016331	159	0.170
skeletal system development	GO:0001501	356	0.169	Mouse
leukocyte differentiation	GO:0002521	342	0.166	Mouse
cellular lipid metabolic process	GO:0044255	323	0.166
kidney development	GO:0001822	213	0.161
regulation of nucleotide metabolic process	GO:0006140	169	0.160
lymphocyte differentiation	GO:0030098	242	0.157	Mouse
regulation of secretion	GO:0051046	274	0.154
purine containing compound catabolic process	GO:0072523	213	0.154
bone development	GO:0060348	120	0.152
cellular amine metabolic process	GO:0044106	44	0.152
purine ribonucleotide metabolic process	GO:0009150	290	0.151
regionalization	GO:0003002	337	0.150
stem cell development	GO:0048864	219	0.149
nucleotide metabolic process	GO:0009117	332	0.146
epithelial tube morphogenesis	GO:0060562	303	0.144
ureteric bud development	GO:0001657	94	0.142
regulation of multi organism process	GO:0043900	111	0.141
leukocyte activation involved in immune response	GO:0002366	126	0.141
forebrain development	GO:0030900	302	0.140	Mouse
cellular nitrogen compound catabolic process	GO:0044270	280	0.139
positive regulation of cell morphogenesis involved in differentiation	GO:0010770	72	0.138
cell fate commitment	GO:0045165	210	0.133
carbohydrate derivative catabolic process	GO:1901136	231	0.131
purine nucleotide metabolic process	GO:0006163	302	0.130
cellular amino acid metabolic process	GO:0006520	103	0.130
organophosphate catabolic process	GO:0046434	232	0.129
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.125
axonogenesis	GO:0007409	274	0.123	Mouse
glycosyl compound metabolic process	GO:1901657	246	0.122
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.121
regulation of cellular response to stress	GO:0080135	159	0.120
oxidation reduction process	GO:0055114	342	0.119
b cell activation	GO:0042113	161	0.118
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.116	Mouse
muscle system process	GO:0003012	141	0.116
nucleoside catabolic process	GO:0009164	206	0.115
regulation of rho protein signal transduction	GO:0035023	71	0.115
purine nucleoside catabolic process	GO:0006152	205	0.115
cell recognition	GO:0008037	83	0.114
regulation of neuron differentiation	GO:0045664	281	0.113	Mouse
chemotaxis	GO:0006935	247	0.113	Mouse
embryonic limb morphogenesis	GO:0030326	126	0.112
positive regulation of nervous system development	GO:0051962	221	0.112
regulation of rho gtpase activity	GO:0032319	58	0.111
cytokine production	GO:0001816	319	0.110	Mouse
mesenchyme development	GO:0060485	152	0.109
t cell differentiation	GO:0030217	174	0.109
epidermis development	GO:0008544	187	0.109
digestive system development	GO:0055123	200	0.109
blood vessel morphogenesis	GO:0048514	285	0.108
branching involved in salivary gland morphogenesis	GO:0060445	26	0.107	Mouse
mesonephros development	GO:0001823	97	0.107
positive regulation of cell development	GO:0010720	237	0.106
regulation of apoptotic signaling pathway	GO:2001233	197	0.105
blood circulation	GO:0008015	195	0.105
positive regulation of programmed cell death	GO:0043068	218	0.105
regulation of nucleoside metabolic process	GO:0009118	130	0.104
purine ribonucleoside metabolic process	GO:0046128	241	0.104
branching morphogenesis of an epithelial tube	GO:0048754	159	0.103
ossification	GO:0001503	216	0.103
cation homeostasis	GO:0055080	212	0.102
macromolecule catabolic process	GO:0009057	281	0.102
membrane organization	GO:0061024	245	0.101
muscle tissue development	GO:0060537	308	0.101	Mouse
digestive tract morphogenesis	GO:0048546	147	0.101
epithelial cell development	GO:0002064	159	0.101
ribose phosphate metabolic process	GO:0019693	291	0.100
alpha beta t cell differentiation	GO:0046632	69	0.100
telencephalon development	GO:0021537	186	0.100	Mouse
kidney morphogenesis	GO:0060993	83	0.099
organic anion transport	GO:0015711	137	0.099
negative regulation of neuron projection development	GO:0010977	50	0.099	Mouse
regulation of neuron projection development	GO:0010975	169	0.098	Mouse
nucleoside metabolic process	GO:0009116	246	0.098
regulation of cell migration	GO:0030334	219	0.096
regulation of cell motility	GO:2000145	236	0.096
negative regulation of epithelial cell proliferation	GO:0050680	64	0.096
positive regulation of cell death	GO:0010942	224	0.095
nucleoside triphosphate metabolic process	GO:0009141	230	0.094
respiratory tube development	GO:0030323	167	0.094
transmembrane transport	GO:0055085	412	0.094
regulation of gtp catabolic process	GO:0033124	113	0.094
negative regulation of cell activation	GO:0050866	111	0.093	Mouse
lymphocyte activation involved in immune response	GO:0002285	93	0.093
renal tubule morphogenesis	GO:0061333	72	0.092
odontogenesis of dentin containing tooth	GO:0042475	66	0.091
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.091
regulation of anatomical structure size	GO:0090066	178	0.090	Mouse
nucleoside triphosphate catabolic process	GO:0009143	205	0.090
regulation of purine nucleotide metabolic process	GO:1900542	169	0.088
regulation of neuron death	GO:1901214	134	0.088	Mouse
guanosine containing compound catabolic process	GO:1901069	144	0.088
glycosyl compound catabolic process	GO:1901658	206	0.088
ribonucleotide catabolic process	GO:0009261	208	0.088
circulatory system process	GO:0003013	197	0.087
defense response to bacterium	GO:0042742	119	0.086
cell adhesion	GO:0007155	329	0.086	Mouse
trachea cartilage morphogenesis	GO:0060535	4	0.086
metanephros development	GO:0001656	79	0.085
immune response activating signal transduction	GO:0002757	116	0.084	Mouse
purine nucleoside metabolic process	GO:0042278	241	0.084
gtp catabolic process	GO:0006184	143	0.083
leukocyte apoptotic process	GO:0071887	71	0.083
metal ion homeostasis	GO:0055065	189	0.083
protein maturation	GO:0051604	176	0.083
morphogenesis of a branching epithelium	GO:0061138	193	0.083	Mouse
organic hydroxy compound biosynthetic process	GO:1901617	77	0.082
purine ribonucleoside catabolic process	GO:0046130	205	0.082
nephric duct formation	GO:0072179	4	0.082
negative regulation of neuron death	GO:1901215	98	0.082	Mouse
regulation of kinase activity	GO:0043549	249	0.081	Human Mouse
protein catabolic process	GO:0030163	221	0.080
regulation of epithelial cell proliferation	GO:0050678	141	0.080
positive regulation of protein phosphorylation	GO:0001934	242	0.079	Human Mouse
positive regulation of nucleotide catabolic process	GO:0030813	88	0.079
fat cell differentiation	GO:0045444	160	0.079
camera type eye development	GO:0043010	266	0.079	Mouse
regulation of defense response	GO:0031347	233	0.079	Mouse
skeletal system morphogenesis	GO:0048705	203	0.078	Mouse
oviduct development	GO:0060066	3	0.078
immune response regulating signaling pathway	GO:0002764	125	0.077	Mouse
negative regulation of multi organism process	GO:0043901	68	0.076
odontogenesis	GO:0042476	78	0.076
guanosine containing compound metabolic process	GO:1901068	144	0.075
organophosphate biosynthetic process	GO:0090407	122	0.075
alpha beta t cell activation	GO:0046631	91	0.075
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.074
purine nucleotide catabolic process	GO:0006195	211	0.074
muscle contraction	GO:0006936	101	0.074
angiogenesis	GO:0001525	201	0.074
regulation of nucleotide catabolic process	GO:0030811	122	0.073
nephron tubule morphogenesis	GO:0072078	68	0.073
nephron development	GO:0072006	109	0.073
ribonucleoside metabolic process	GO:0009119	245	0.073
positive regulation of mapk cascade	GO:0043410	170	0.072	Human Mouse
lipid biosynthetic process	GO:0008610	179	0.072
skin development	GO:0043588	220	0.072
negative regulation of cell motility	GO:2000146	61	0.071
positive regulation of map kinase activity	GO:0043406	84	0.071	Human Mouse
peptidyl amino acid modification	GO:0018193	336	0.071	Mouse
response to organic cyclic compound	GO:0014070	198	0.071
cellular macromolecule catabolic process	GO:0044265	206	0.070
regulation of cell projection organization	GO:0031344	206	0.070	Mouse
regulation of protein complex assembly	GO:0043254	83	0.070
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.070
regulation of cell adhesion	GO:0030155	154	0.070
regulation of secretion by cell	GO:1903530	249	0.069
inner ear morphogenesis	GO:0042472	101	0.068
activation of immune response	GO:0002253	138	0.068	Mouse
positive regulation of secretion by cell	GO:1903532	114	0.068
ribonucleoside catabolic process	GO:0042454	206	0.068
appendage morphogenesis	GO:0035107	149	0.066
cell activation involved in immune response	GO:0002263	126	0.066
regulation of purine nucleotide catabolic process	GO:0033121	122	0.066
glycoprotein biosynthetic process	GO:0009101	89	0.066
appendage development	GO:0048736	166	0.066
nephron epithelium morphogenesis	GO:0072088	68	0.066
positive regulation of hydrolase activity	GO:0051345	148	0.065
respiratory system development	GO:0060541	190	0.065
cellular response to biotic stimulus	GO:0071216	92	0.064
glycoprotein metabolic process	GO:0009100	116	0.064
nucleotide catabolic process	GO:0009166	217	0.063
exocrine system development	GO:0035272	45	0.063	Mouse
small molecule biosynthetic process	GO:0044283	132	0.063
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.063	Mouse
actin cytoskeleton organization	GO:0030036	220	0.063
mesoderm morphogenesis	GO:0048332	64	0.062
regulation of proteolysis	GO:0030162	164	0.062
hindbrain development	GO:0030902	128	0.062
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.062
cellular ketone metabolic process	GO:0042180	84	0.061
regulation of reproductive process	GO:2000241	66	0.060
regulation of chemotaxis	GO:0050920	53	0.060	Mouse
stem cell differentiation	GO:0048863	268	0.060
formation of primary germ layer	GO:0001704	77	0.060
peptidyl tyrosine modification	GO:0018212	145	0.060	Mouse
regulation of vesicle mediated transport	GO:0060627	139	0.060
negative regulation of cellular component organization	GO:0051129	194	0.060	Mouse
positive regulation of cellular amine metabolic process	GO:0033240	5	0.059
membrane depolarization	GO:0051899	64	0.059	Mouse
anion transport	GO:0006820	177	0.059
regulation of organelle organization	GO:0033043	289	0.059
connective tissue development	GO:0061448	179	0.059
positive regulation of ras gtpase activity	GO:0032320	65	0.059
bone mineralization	GO:0030282	54	0.058
monocarboxylic acid metabolic process	GO:0032787	191	0.058
regulation of organ morphogenesis	GO:2000027	144	0.058	Mouse
limb morphogenesis	GO:0035108	149	0.058
placenta development	GO:0001890	140	0.058	Mouse
male gamete generation	GO:0048232	285	0.058	Mouse
defense response to other organism	GO:0098542	197	0.058
peptide metabolic process	GO:0006518	46	0.057
neuron apoptotic process	GO:0051402	142	0.057	Mouse
regulation of neuron apoptotic process	GO:0043523	122	0.057	Mouse
positive regulation of cellular component biogenesis	GO:0044089	94	0.057
cellular response to cytokine stimulus	GO:0071345	189	0.056
organonitrogen compound catabolic process	GO:1901565	264	0.056
mesonephric tubule development	GO:0072164	94	0.056
regulation of inflammatory response	GO:0050727	147	0.056	Mouse
positive regulation of secretion	GO:0051047	130	0.055
regulation of cell activation	GO:0050865	289	0.055	Mouse
cytokine secretion	GO:0050663	72	0.055
positive regulation of nucleoside metabolic process	GO:0045979	91	0.055
carbohydrate derivative biosynthetic process	GO:1901137	183	0.054
lymphocyte proliferation	GO:0046651	164	0.054
neuron projection extension	GO:1990138	64	0.054	Mouse
specification of organ identity	GO:0010092	30	0.053
ureteric bud morphogenesis	GO:0060675	62	0.053
cell maturation	GO:0048469	127	0.053
cation transmembrane transport	GO:0098655	266	0.053
positive regulation of cell migration	GO:0030335	109	0.052
regulation of cellular ketone metabolic process	GO:0010565	66	0.052
spermatogenesis	GO:0007283	284	0.052	Mouse
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.052	Human Mouse
regulation of alpha beta t cell activation	GO:0046634	53	0.052
regulation of body fluid levels	GO:0050878	162	0.052	Mouse
positive regulation of protein kinase activity	GO:0045860	144	0.052	Human Mouse
neuron projection guidance	GO:0097485	141	0.052	Mouse
endochondral bone morphogenesis	GO:0060350	50	0.052
cellular response to growth factor stimulus	GO:0071363	197	0.051
cellular ion homeostasis	GO:0006873	165	0.051
cation transport	GO:0006812	399	0.051
gtp metabolic process	GO:0046039	144	0.051
killing of cells in other organism involved in symbiotic interaction	GO:0051883	13	0.051
response to growth factor	GO:0070848	198	0.051
regulation of protein secretion	GO:0050708	82	0.051
positive regulation of lymphocyte activation	GO:0051251	140	0.050
regulation of cell size	GO:0008361	72	0.050	Mouse
mesonephric duct morphogenesis	GO:0072180	4	0.050
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.050
modification dependent protein catabolic process	GO:0019941	133	0.049
fibroblast growth factor production	GO:0090269	4	0.049
regulation of cellular amine metabolic process	GO:0033238	20	0.049
locomotory behavior	GO:0007626	195	0.049
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.049
modification dependent macromolecule catabolic process	GO:0043632	133	0.049
embryonic skeletal system morphogenesis	GO:0048704	91	0.048
regulation of lymphocyte activation	GO:0051249	240	0.048	Mouse
calcium ion homeostasis	GO:0055074	127	0.048
positive regulation of leukocyte proliferation	GO:0070665	73	0.048
regulation of branching involved in ureteric bud morphogenesis	GO:0090189	22	0.048
g protein coupled receptor signaling pathway	GO:0007186	243	0.048
limb development	GO:0060173	166	0.047
regulation of protein localization	GO:0032880	231	0.047
regulation of t cell activation	GO:0050863	170	0.047
positive regulation of cellular catabolic process	GO:0031331	148	0.046
positive regulation of transferase activity	GO:0051347	167	0.046	Human Mouse
regulation of angiogenesis	GO:0045765	81	0.046
phenol containing compound metabolic process	GO:0018958	60	0.046
inorganic cation transmembrane transport	GO:0098662	207	0.046
myoblast differentiation involved in skeletal muscle regeneration	GO:0014835	3	0.046
carbohydrate metabolic process	GO:0005975	230	0.046
tube formation	GO:0035148	140	0.045
regulation of fat cell differentiation	GO:0045598	81	0.045
female gamete generation	GO:0007292	74	0.045
negative regulation of synapse assembly	GO:0051964	3	0.044
regulation of cellular component size	GO:0032535	121	0.044	Mouse
somitogenesis	GO:0001756	69	0.044
negative regulation of cell development	GO:0010721	169	0.044	Mouse
sensory perception	GO:0007600	245	0.044
mesonephric tubule morphogenesis	GO:0072171	63	0.044
regulation of ion transport	GO:0043269	215	0.043
negative regulation of fat cell differentiation	GO:0045599	36	0.043
positive regulation of cytokine production	GO:0001819	174	0.043
leukocyte proliferation	GO:0070661	172	0.043
regulation of leukocyte apoptotic process	GO:2000106	56	0.043
actin filament organization	GO:0007015	113	0.043
organonitrogen compound biosynthetic process	GO:1901566	192	0.043
negative regulation of cell migration	GO:0030336	59	0.042
heart morphogenesis	GO:0003007	178	0.042
positive regulation of cell projection organization	GO:0031346	95	0.042
lymphocyte mediated immunity	GO:0002449	139	0.042
positive regulation of cell activation	GO:0050867	158	0.042
trabecula morphogenesis	GO:0061383	40	0.042
negative regulation of molecular function	GO:0044092	258	0.042
organ growth	GO:0035265	117	0.042
ameboidal type cell migration	GO:0001667	128	0.042
coagulation	GO:0050817	78	0.042	Mouse
protein modification by small protein conjugation	GO:0032446	187	0.041
embryonic appendage morphogenesis	GO:0035113	126	0.041
neural tube formation	GO:0001841	108	0.041
male gonad development	GO:0008584	88	0.041
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.041
regulation of mitotic cell cycle	GO:0007346	126	0.041
oocyte differentiation	GO:0009994	35	0.041
gonad development	GO:0008406	141	0.041
cardiac muscle tissue development	GO:0048738	130	0.040
peptidyl tyrosine phosphorylation	GO:0018108	143	0.040	Mouse
nephron epithelium development	GO:0072009	92	0.040
organic acid transport	GO:0015849	101	0.040
regulation of peptidase activity	GO:0052547	96	0.040
positive regulation of epithelial cell proliferation	GO:0050679	68	0.040
positive regulation of purine nucleotide catabolic process	GO:0033123	88	0.040
positive regulation of rho gtpase activity	GO:0032321	41	0.039
nephron tubule development	GO:0072080	84	0.039
male sex differentiation	GO:0046661	109	0.039
mitotic cell cycle	GO:0000278	195	0.039
multicellular organism growth	GO:0035264	161	0.039
regulation of map kinase activity	GO:0043405	120	0.039	Human Mouse
regulation of cell cycle	GO:0051726	281	0.039
mesenchymal cell differentiation	GO:0048762	107	0.039
leukocyte mediated immunity	GO:0002443	174	0.039
t cell proliferation	GO:0042098	120	0.039
interleukin 8 secretion	GO:0072606	3	0.038
arachidonic acid metabolite production involved in inflammatory response	GO:0002538	2	0.038
forebrain cell migration	GO:0021885	58	0.038	Mouse
regulation of extent of cell growth	GO:0061387	52	0.038	Mouse
positive regulation of nucleotide metabolic process	GO:0045981	114	0.038
oocyte development	GO:0048599	33	0.038
gastrulation	GO:0007369	116	0.038
positive regulation of neuron differentiation	GO:0045666	141	0.038
positive regulation of apoptotic signaling pathway	GO:2001235	95	0.038
skeletal muscle organ development	GO:0060538	163	0.037	Mouse
positive regulation of gtp catabolic process	GO:0033126	85	0.037
regulation of anagen	GO:0051884	1	0.037
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.037
regulation of lymphocyte differentiation	GO:0045619	107	0.037
negative regulation of t cell activation	GO:0050868	65	0.036
divalent inorganic cation homeostasis	GO:0072507	138	0.036
sodium ion transport	GO:0006814	73	0.036
regulation of protein serine threonine kinase activity	GO:0071900	157	0.036	Human Mouse
embryonic organ morphogenesis	GO:0048562	276	0.036
response to oxidative stress	GO:0006979	123	0.036
myeloid leukocyte differentiation	GO:0002573	119	0.036
lymphocyte apoptotic process	GO:0070227	54	0.036
paraxial mesodermal cell fate commitment	GO:0048343	2	0.036
mesenchymal cell development	GO:0014031	93	0.036
biomineral tissue development	GO:0031214	64	0.036
cellular amide metabolic process	GO:0043603	58	0.036
positive regulation of growth	GO:0045927	104	0.036
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.036
positive regulation of cell cycle	GO:0045787	92	0.035
ear development	GO:0043583	200	0.035
innate immune response	GO:0045087	157	0.035	Mouse
muscle cell differentiation	GO:0042692	261	0.035	Mouse
mesoderm formation	GO:0001707	62	0.035
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.035
positive regulation of organelle organization	GO:0010638	128	0.035
adaptive immune response	GO:0002250	155	0.035
g1 s transition of mitotic cell cycle	GO:0000082	57	0.035
compound eye development	GO:0048749	1	0.035
interspecies interaction between organisms	GO:0044419	83	0.035
endocardial cushion to mesenchymal transition involved in heart valve formation	GO:0003199	4	0.035
regulation of cellular response to growth factor stimulus	GO:0090287	82	0.035
t cell differentiation in thymus	GO:0033077	77	0.035
negative regulation of cell proliferation	GO:0008285	296	0.034
protein localization to membrane	GO:0072657	108	0.034
leukocyte migration	GO:0050900	124	0.034
positive regulation of gtpase activity	GO:0043547	85	0.034
segmentation	GO:0035282	93	0.034
central nervous system neuron differentiation	GO:0021953	162	0.034
tissue homeostasis	GO:0001894	115	0.034
fatty acid metabolic process	GO:0006631	121	0.034
regulation of cellular component biogenesis	GO:0044087	181	0.033
antimicrobial peptide production	GO:0002775	2	0.033
regulation of leukocyte differentiation	GO:1902105	159	0.033
positive regulation of mesonephros development	GO:0061213	20	0.033
palate development	GO:0060021	76	0.033
cellular response to oxidative stress	GO:0034599	76	0.033
positive regulation of neuron projection development	GO:0010976	79	0.032
positive regulation of immune effector process	GO:0002699	107	0.032
regulation of hormone levels	GO:0010817	211	0.032
amine metabolic process	GO:0009308	45	0.032
muscle cell proliferation	GO:0033002	52	0.032
postganglionic parasympathetic nervous system development	GO:0021784	2	0.032
sphingolipid metabolic process	GO:0006665	45	0.032
limbic system development	GO:0021761	72	0.032
adult locomotory behavior	GO:0008344	91	0.032
single organism cell adhesion	GO:0098602	156	0.032	Mouse
multicellular organismal homeostasis	GO:0048871	164	0.032
amide transport	GO:0042886	138	0.031
negative regulation of prostatic bud formation	GO:0060686	4	0.031
embryonic digit morphogenesis	GO:0042733	56	0.031
intrinsic apoptotic signaling pathway	GO:0097193	132	0.031
zygotic determination of anterior posterior axis embryo	GO:0007354	3	0.031
negative regulation of neuron apoptotic process	GO:0043524	92	0.031	Mouse
cellular response to monosaccharide stimulus	GO:0071326	47	0.031
cd4 positive alpha beta t cell differentiation	GO:0043367	41	0.031
positive regulation of t cell activation	GO:0050870	101	0.031
phosphatidylethanolamine biosynthetic process	GO:0006646	2	0.031
regulation of morphogenesis of a branching structure	GO:0060688	53	0.031	Mouse
transdifferentiation	GO:0060290	1	0.031
cellular homeostasis	GO:0019725	240	0.030	Mouse
regulation of myeloid cell differentiation	GO:0045637	96	0.030
morphogenesis of an epithelial fold	GO:0060571	28	0.030
positive regulation of leukocyte differentiation	GO:1902107	86	0.030
leukotriene production involved in inflammatory response	GO:0002540	2	0.030
protein modification by small protein conjugation or removal	GO:0070647	207	0.030
regulation of homeostatic process	GO:0032844	182	0.030
regulation of cell substrate adhesion	GO:0010810	73	0.029
stem cell maintenance	GO:0019827	130	0.029
metanephric epithelium development	GO:0072207	21	0.029
planar cell polarity pathway involved in ventricular septum morphogenesis	GO:0061348	2	0.029
cellular metal ion homeostasis	GO:0006875	151	0.029
mammary gland morphogenesis	GO:0060443	54	0.029
lateral sprouting involved in mammary gland duct morphogenesis	GO:0060599	2	0.029
lymphocyte migration	GO:0072676	26	0.029
bone morphogenesis	GO:0060349	78	0.029
t cell activation involved in immune response	GO:0002286	43	0.029
regulation of transferase activity	GO:0051338	263	0.029	Human Mouse
aortic valve morphogenesis	GO:0003180	4	0.029
neurotransmitter secretion	GO:0007269	62	0.029
embryonic skeletal system development	GO:0048706	120	0.029
myotube differentiation	GO:0014902	105	0.029	Mouse
development of primary male sexual characteristics	GO:0046546	88	0.029
bmp signaling pathway	GO:0030509	93	0.029
response to molecule of bacterial origin	GO:0002237	143	0.029
regulation of alpha beta t cell differentiation	GO:0046637	35	0.029
carboxylic acid transport	GO:0046942	100	0.029
t cell apoptotic process	GO:0070231	39	0.029
myeloid cell homeostasis	GO:0002262	114	0.028	Mouse
regulation of protein transport	GO:0051223	163	0.028
positive regulation of epithelial cell proliferation involved in lung morphogenesis	GO:0060501	3	0.028
muscle cell development	GO:0055001	133	0.028
ubiquitin dependent smad protein catabolic process	GO:0030579	2	0.028
anatomical structure maturation	GO:0071695	49	0.028
wnt signaling pathway involved in forebrain neuroblast division	GO:0021874	2	0.028
positive regulation of synapse assembly	GO:0051965	18	0.028
salivary gland morphogenesis	GO:0007435	33	0.028	Mouse
pallium development	GO:0021543	120	0.028
sphingolipid biosynthetic process	GO:0030148	26	0.028
neural tube development	GO:0021915	160	0.028
regulation of muscle system process	GO:0090257	80	0.028
blood coagulation	GO:0007596	76	0.028	Mouse
establishment of planar polarity involved in nephron morphogenesis	GO:0072046	1	0.028
neutrophil mediated killing of gram positive bacterium	GO:0070946	2	0.028
regulation of chondrocyte differentiation	GO:0032330	33	0.028
regulation of cytokine secretion	GO:0050707	61	0.028
regulation of cytoskeleton organization	GO:0051493	122	0.028
mesonephric duct formation	GO:0072181	2	0.028
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.028
development of primary sexual characteristics	GO:0045137	143	0.027
meiotic cell cycle	GO:0051321	122	0.027
head morphogenesis	GO:0060323	34	0.027
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway	GO:0051482	4	0.027
organic hydroxy compound transport	GO:0015850	93	0.027
ear morphogenesis	GO:0042471	118	0.027
lung morphogenesis	GO:0060425	50	0.027
regulation of stem cell differentiation	GO:2000736	50	0.027
mesoderm development	GO:0007498	100	0.027
central nervous system morphogenesis	GO:0021551	2	0.027
paramesonephric duct development	GO:0061205	3	0.027

Mst1r disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.222
musculoskeletal system disease	DOID:17	0.222
disease of metabolism	DOID:0014667	0.038
bone disease	DOID:0080001	0.032
connective tissue disease	DOID:65	0.032

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