Mus musculus

35 known processes

Setx

senataxin

(Aliases: mKIAA0625,SCAR1,Als4,AW060766,A930037J23Rik,A130090N03,AOA2,Sen1)

Setx biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
histone h3 k9 methylationGO:0051567170.666
negative regulation of histone methylationGO:0031061100.599
histone methylationGO:0016571710.587
histone lysine methylationGO:0034968500.544
positive regulation of histone h3 k27 methylationGO:006108740.459
protein methylationGO:0006479810.373
positive regulation of histone h3 k9 methylationGO:005157440.371
regulation of chromosome organizationGO:0033044830.288
protein alkylationGO:0008213810.273
positive regulation of chromatin modificationGO:1903310280.268
regulation of histone h3 k9 methylationGO:005157080.238
regulation of histone methylationGO:0031060300.207
dna modificationGO:0006304500.197
positive regulation of histone methylationGO:0031062160.172
macromolecule methylationGO:00434141200.161
protein localization to organelleGO:00333651850.153
peptidyl amino acid modificationGO:00181933360.138
purine containing compound metabolic processGO:00725213110.137
regulation of chromatin modificationGO:1903308570.133
stem cell differentiationGO:00488632680.129
ribose phosphate metabolic processGO:00196932910.126
ribonucleoside triphosphate metabolic processGO:00091992200.122
purine ribonucleoside triphosphate metabolic processGO:00092052200.115
dna metabolic processGO:00062593030.113
negative regulation of cellular component organizationGO:00511291940.113
covalent chromatin modificationGO:00165691630.109
ras protein signal transductionGO:0007265770.106
nucleoside triphosphate catabolic processGO:00091432050.100
purine ribonucleoside triphosphate catabolic processGO:00092071990.097
glycosyl compound catabolic processGO:19016582060.096
ribonucleoside metabolic processGO:00091192450.095
nucleosome positioningGO:001658440.093
stem cell developmentGO:00488642190.091
methylationGO:00322591340.090
histone h3 k27 methylationGO:0070734110.089
regulation of histone h3 k27 methylationGO:006108560.088
purine containing compound catabolic processGO:00725232130.087
protein localization to chromatinGO:007116830.087
ribonucleoside triphosphate catabolic processGO:00092031990.085
nucleoside metabolic processGO:00091162460.084
purine nucleoside metabolic processGO:00422782410.083
purine nucleoside triphosphate catabolic processGO:00091462030.082
small gtpase mediated signal transductionGO:0007264970.082
histone modificationGO:00165701590.080
purine ribonucleoside catabolic processGO:00461302050.080
purine nucleoside catabolic processGO:00061522050.079
maintenance of cell numberGO:009872730.078
ribonucleotide metabolic processGO:00092592910.078
nucleoside triphosphate metabolic processGO:00091412300.076
stem cell maintenanceGO:00198271300.075
ribonucleoside catabolic processGO:00424542060.075
purine ribonucleotide metabolic processGO:00091502900.073
purine nucleotide catabolic processGO:00061952110.072
negative regulation of cell proliferationGO:00082852960.072
negative regulation of transcription elongation from rna polymerase ii promoterGO:003424460.071
positive regulation of organelle organizationGO:00106381280.071
purine ribonucleotide catabolic processGO:00091542080.068
nucleoside phosphate catabolic processGO:19012922220.066
regulation of organelle organizationGO:00330432890.065
negative regulation of chromosome organizationGO:2001251300.065
digestive tract morphogenesisGO:00485461470.064
ribonucleotide catabolic processGO:00092612080.064
regulation of apoptotic signaling pathwayGO:20012331970.064
mitotic cell cycle processGO:19030471590.064
male gamete generationGO:00482322850.062
nucleotide catabolic processGO:00091662170.062
purine nucleoside triphosphate metabolic processGO:00091442260.061
nucleoside catabolic processGO:00091642060.061
organic cyclic compound catabolic processGO:19013612950.058
regulation of cellular ketone metabolic processGO:0010565660.057
positive regulation of chromosome organizationGO:2001252330.056
nucleotide metabolic processGO:00091173320.055
purine nucleotide metabolic processGO:00061633020.053
intracellular protein transportGO:00068862040.051
nucleoside phosphate metabolic processGO:00067533380.051
chromatin organizationGO:00063252060.050
mapk cascadeGO:00001652810.050
purine ribonucleoside metabolic processGO:00461282410.049
genetic imprintingGO:0071514270.049
spermatogenesisGO:00072832840.049
nucleobase containing small molecule metabolic processGO:00550863520.048
protein modification by small protein conjugation or removalGO:00706472070.047
skeletal muscle satellite cell maintenance involved in skeletal muscle regenerationGO:001483430.047
guanosine containing compound metabolic processGO:19010681440.046
regulation of transferase activityGO:00513382630.046
nuclear transportGO:00511691390.046
organophosphate catabolic processGO:00464342320.045
heterocycle catabolic processGO:00467002800.045
organonitrogen compound catabolic processGO:19015652640.045
positive regulation of protein modification processGO:00314012990.044
positive regulation of histone modificationGO:0031058280.043
glycosyl compound metabolic processGO:19016572460.043
cellular amino acid metabolic processGO:00065201030.043
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.042
aromatic compound catabolic processGO:00194392860.042
maintenance of protein location in nucleusGO:005145720.042
regulation of protein serine threonine kinase activityGO:00719001570.041
cellular response to dna damage stimulusGO:00069742070.041
positive regulation of transferase activityGO:00513471670.039
nucleocytoplasmic transportGO:00069131390.038
positive regulation of gtpase activityGO:0043547850.038
regulation of chromatin organizationGO:1902275570.038
cellular amine metabolic processGO:0044106440.037
cellular nitrogen compound catabolic processGO:00442702800.036
membrane organizationGO:00610242450.035
cytoplasmic transportGO:00164822340.035
carbohydrate derivative catabolic processGO:19011362310.035
dendrite developmentGO:00163581150.034
apoptotic signaling pathwayGO:00971903060.034
gtp metabolic processGO:00460391440.033
chromatin modificationGO:00165681870.033
negative regulation of protein metabolic processGO:00512482820.032
regulation of neuron differentiationGO:00456642810.032
regulation of nucleoside metabolic processGO:00091181300.032
cellular response to organonitrogen compoundGO:00714171450.031
regulation of cellular component biogenesisGO:00440871810.031
regulation of cellular amino acid metabolic processGO:000652150.031
positive regulation of purine nucleotide catabolic processGO:0033123880.031
regulation of mapk cascadeGO:00434082480.031
response to ionizing radiationGO:0010212420.031
dna methylationGO:0006306430.031
microtubule based processGO:00070172360.030
posttranscriptional regulation of gene expressionGO:00106081550.030
positive regulation of cellular amine metabolic processGO:003324050.030
gland developmentGO:00487323300.029
peptidyl serine modificationGO:0018209830.029
cellular lipid metabolic processGO:00442553230.029
cytokinetic processGO:003250620.029
protein localization to nucleusGO:00345041210.028
peptidyl serine phosphorylationGO:0018105740.028
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046610.028
regulation of protein kinase activityGO:00458592320.028
cilium morphogenesisGO:00602711020.027
organelle assemblyGO:00709251770.027
positive regulation of programmed cell deathGO:00430682180.027
protein ubiquitinationGO:00165671710.027
germ line stem cell divisionGO:004207820.026
single organism nuclear importGO:1902593950.026
positive regulation of protein serine threonine kinase activityGO:00719021060.026
synaptic transmissionGO:00072683290.026
regulation of intracellular transportGO:00323861590.026
regulation of multi organism processGO:00439001110.026
regulation of synaptic growth at neuromuscular junctionGO:000858240.026
regulation of histone modificationGO:0031056560.026
spindle assembly involved in mitosisGO:009030740.025
positive regulation of hydrolase activityGO:00513451480.025
circadian rhythmGO:00076231140.025
cell type specific apoptotic processGO:00972852680.025
axonogenesisGO:00074092740.025
cell divisionGO:00513011200.025
gtp catabolic processGO:00061841430.025
peptidyl lysine methylationGO:0018022290.025
cellular ketone metabolic processGO:0042180840.024
response to lipopolysaccharideGO:00324961280.024
positive regulation of protein phosphorylationGO:00019342420.023
regulation of ras protein signal transductionGO:00465781140.023
digestive system developmentGO:00551232000.023
purine nucleoside monophosphate catabolic processGO:0009128580.023
hindbrain developmentGO:00309021280.023
regulation of synapse structural plasticityGO:005182340.023
positive regulation of cell developmentGO:00107202370.022
amine metabolic processGO:0009308450.022
regulation of intracellular protein transportGO:0033157820.022
protein targetingGO:00066051430.022
actin cytoskeleton organizationGO:00300362200.022
regulation of ras gtpase activityGO:0032318880.022
positive regulation of nucleotide metabolic processGO:00459811140.022
positive regulation of cell activationGO:00508671580.021
regulation of mrna processingGO:0050684410.021
rna interferenceGO:001624620.021
viral processGO:0016032410.021
dna repairGO:00062811070.021
regulation of protein stabilityGO:0031647520.021
regulation of gtp catabolic processGO:00331241130.021
digestive tract developmentGO:00485651900.021
mitotic cytokinesisGO:000028140.021
positive regulation of mapk cascadeGO:00434101700.021
hepaticobiliary system developmentGO:0061008670.021
rna splicingGO:0008380540.020
regulation of purine nucleotide catabolic processGO:00331211220.020
cellular response to oxidative stressGO:0034599760.020
embryonic digestive tract developmentGO:0048566270.020
viral gene expressionGO:001908030.020
regulation of establishment of protein localizationGO:00702011810.020
liver developmentGO:0001889660.020
negative regulation of organelle organizationGO:0010639900.020
mrna metabolic processGO:0016071840.020
purine ribonucleoside monophosphate metabolic processGO:0009167800.019
regulation of protein localizationGO:00328802310.019
axon guidanceGO:00074111410.019
segmentationGO:0035282930.019
regulation of cytoplasmic transportGO:19036491120.019
regulation of nucleocytoplasmic transportGO:0046822730.019
regulation of cellular amine metabolic processGO:0033238200.019
dna recombinationGO:0006310920.019
guanosine containing compound catabolic processGO:19010691440.019
positive regulation of cellular amino acid metabolic processGO:004576430.019
nuclear importGO:0051170950.018
regulation of cellular catabolic processGO:00313292420.018
muscle cell differentiationGO:00426922610.018
positive regulation of apoptotic processGO:00430652170.018
negative regulation of cellular protein metabolic processGO:00322692470.018
regulation of protein transportGO:00512231630.018
posttranscriptional gene silencingGO:0016441100.018
glycerolipid metabolic processGO:00464861220.018
establishment of protein localization to organelleGO:00725941180.018
nuclear divisionGO:00002801580.018
nucleoside monophosphate metabolic processGO:0009123850.018
lipid biosynthetic processGO:00086101790.017
carbohydrate derivative biosynthetic processGO:19011371830.017
histone ubiquitinationGO:0016574100.017
development of primary sexual characteristicsGO:00451371430.017
cellular homeostasisGO:00197252400.017
regulation of mrna splicing via spliceosomeGO:0048024320.017
metencephalon developmentGO:0022037890.017
negative regulation of cellular amino acid metabolic processGO:004576300.017
regulation of nucleotide metabolic processGO:00061401690.017
dendrite self avoidanceGO:007059320.017
ventral midline developmentGO:000741840.017
innate immune responseGO:00450871570.017
purine ribonucleoside monophosphate catabolic processGO:0009169570.017
interspecies interaction between organismsGO:0044419830.017
cellular protein complex assemblyGO:00436231160.017
forebrain developmentGO:00309003020.017
negative regulation of chromatin modificationGO:1903309190.016
intracellular receptor signaling pathwayGO:0030522740.016
regulation of purine nucleotide metabolic processGO:19005421690.016
nucleoside monophosphate catabolic processGO:0009125590.016
regulation of cell growthGO:0001558910.016
response to extracellular stimulusGO:00099911270.016
regulation of kinase activityGO:00435492490.016
negative regulation of fibroblast proliferationGO:0048147140.016
actin filament organizationGO:00070151130.016
regulation of vesicle mediated transportGO:00606271390.016
peptidyl lysine modificationGO:0018205770.016
microtubule based movementGO:0007018840.016
regulation of nucleotide catabolic processGO:00308111220.016
regulation of rna splicingGO:0043484370.016
regulation of cell cycle g1 s phase transitionGO:1902806350.016
neuron deathGO:00709971540.015
regulation of hormone levelsGO:00108172110.015
positive regulation of purine nucleotide metabolic processGO:19005441140.015
positive regulation of nucleoside metabolic processGO:0045979910.015
gliogenesisGO:00420631410.015
placenta developmentGO:00018901400.015
protein import into nucleusGO:0006606950.015
regulation of map kinase activityGO:00434051200.015
regulation of protein targetingGO:1903533610.015
regulation of cell projection organizationGO:00313442060.015
engulfment of apoptotic cellGO:004365230.015
negative regulation of histone h3 k9 methylationGO:005157340.014
viral life cycleGO:0019058360.014
neural tube developmentGO:00219151600.014
atp metabolic processGO:0046034750.014
organelle localizationGO:00516401790.014
nitrogen compound transportGO:00717052710.014
negative regulation of synapse assemblyGO:005196430.014
regionalizationGO:00030023370.014
negative regulation of apoptotic signaling pathwayGO:20012341040.014
spleen developmentGO:0048536390.014
dna alkylationGO:0006305430.014
microtubule cytoskeleton organization involved in mitosisGO:190285040.014
cell fate commitmentGO:00451652100.014
compound eye developmentGO:004874910.014
adult behaviorGO:00305341350.014
positive regulation of histone h3 k4 methylationGO:005157150.014
neuron apoptotic processGO:00514021420.014
positive regulation of protein transportGO:0051222930.014
negative regulation of cell developmentGO:00107211690.014
establishment or maintenance of actin cytoskeleton polarityGO:003095010.014
negative regulation of growthGO:0045926990.014
cell growthGO:00160491300.014
calcium mediated signalingGO:0019722460.014
response to growth factorGO:00708481980.014
ribonucleoside monophosphate metabolic processGO:0009161800.013
regulation of cytokine productionGO:00018172660.013
regulation of protein import into nucleusGO:0042306520.013
establishment or maintenance of cell polarityGO:0007163860.013
response to nutrient levelsGO:00316671090.013
positive regulation of protein kinase activityGO:00458601440.013
response to hydrogen peroxideGO:0042542320.013
regulation of secretionGO:00510462740.013
multicellular organism growthGO:00352641610.013
locomotory behaviorGO:00076261950.013
embryonic organ morphogenesisGO:00485622760.013
defense response to other organismGO:00985421970.013
negative regulation of nervous system developmentGO:00519611560.013
negative regulation of protein modification processGO:00314001630.013
response to acid chemicalGO:00011011110.013
response to oxidative stressGO:00069791230.013
regulation of lymphocyte activationGO:00512492400.013
negative regulation of cell cycle phase transitionGO:1901988480.013
negative regulation of intracellular signal transductionGO:19025321670.013
regulation of secretion by cellGO:19035302490.013
cleavage involved in rrna processingGO:000046910.013
small molecule biosynthetic processGO:00442831320.013
purine nucleoside monophosphate metabolic processGO:0009126810.013
mrna transportGO:0051028130.012
endomembrane system organizationGO:00102561470.012
internal protein amino acid acetylationGO:0006475420.012
organelle fissionGO:00482851700.012
regulation of actin filament based processGO:0032970990.012
positive regulation of intracellular transportGO:0032388700.012
localization within membraneGO:005166840.012
negative regulation of chromatin silencingGO:003193610.012
atp catabolic processGO:0006200550.012
protein modification by small protein conjugationGO:00324461870.012
regulation of skeletal muscle contractionGO:001481930.012
histone acetylationGO:0016573410.012
protein autophosphorylationGO:0046777610.012
maintenance of protein localization in organelleGO:007259520.012
cellular metal ion homeostasisGO:00068751510.012
regulation of cell morphogenesis involved in differentiationGO:00107691510.012
regulation of striated muscle contractionGO:0006942250.012
reactive oxygen species metabolic processGO:0072593840.012
cellular component assembly involved in morphogenesisGO:00109271390.012
regulation of hydrolase activityGO:00513362460.012
regulation of system processGO:00440572000.012
positive regulation of cellular catabolic processGO:00313311480.012
nucleus localizationGO:0051647200.012
rna 5 end processingGO:000096610.012
cellular chemical homeostasisGO:00550822150.012
rna processingGO:00063961050.012
calcium ion homeostasisGO:00550741270.012
spermatid differentiationGO:00485151150.012
response to organic cyclic compoundGO:00140701980.011
chromatin assemblyGO:0031497130.011
lateral inhibitionGO:004633110.011
protein polymerizationGO:0051258570.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.011
regulation of t cell proliferationGO:0042129920.011
protein localization to chromosomeGO:003450260.011
cation transportGO:00068123990.011
dna templated transcription terminationGO:000635340.011
protein acylationGO:0043543640.011
cognitionGO:00508901490.011
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.011
cellular protein catabolic processGO:00442571550.011
positive regulation of protein import into nucleusGO:0042307260.011
regulation of protein complex assemblyGO:0043254830.011
positive regulation of cell deathGO:00109422240.011
chromosome organization involved in meiosisGO:0070192390.011
viral transcriptionGO:001908330.011
t cell activationGO:00421102890.011
monocarboxylic acid metabolic processGO:00327871910.011
regulation of homeostatic processGO:00328441820.011
negative regulation of cellular amine metabolic processGO:003323910.011
neuron migrationGO:00017641220.011
nucleobase containing compound transportGO:0015931270.011
organic hydroxy compound metabolic processGO:19016152030.011
dna methylation involved in gamete generationGO:0043046150.011
pore complex assemblyGO:004693130.011
endonucleolytic cleavage of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000047910.011
translationGO:0006412930.011
thymus developmentGO:0048538410.011
cell recognitionGO:0008037830.010
regulation of cell cycle processGO:00105641600.010
regenerationGO:0031099380.010
mitotic sister chromatid segregationGO:0000070140.010
response to molecule of bacterial originGO:00022371430.010
regulation of proteolysisGO:00301621640.010
spermatid developmentGO:00072861080.010
regulation of clathrin mediated endocytosisGO:200036940.010
negative regulation of striated muscle cell differentiationGO:0051154140.010
gonad developmentGO:00084061410.010
mitotic cell cycleGO:00002781950.010
negative regulation of dna replicationGO:000815640.010
symbiosis encompassing mutualism through parasitismGO:0044403830.010
positive regulation of cytokine productionGO:00018191740.010
regulation of protein localization to nucleusGO:1900180600.010
divalent inorganic cation homeostasisGO:00725071380.010
cilium assemblyGO:0042384810.010
retrograde transport endosome to golgiGO:004214720.010
myosin filament organizationGO:003103330.010
ribonucleoside monophosphate catabolic processGO:0009158570.010
regulation of cell cycle phase transitionGO:1901987770.010
protein processingGO:00164851630.010

Setx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.040
disease of anatomical entityDOID:700.040
central nervous system diseaseDOID:33100.024
physical disorderDOID:008001500.011
neurodegenerative diseaseDOID:128900.011
neuropathyDOID:87000.010