Mus musculus

7 known processes

Pcolce

procollagen C-endopeptidase enhancer protein

(Aliases: PCPE-1,Astt-2,P14,Astt2)

Pcolce biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
extracellular structure organizationGO:00430621480.856
ossificationGO:00015032160.729
extracellular matrix organizationGO:00301981470.701
cell substrate adhesionGO:00315891300.668
bone developmentGO:00603481200.599
regulation of cell substrate adhesionGO:0010810730.555
connective tissue developmentGO:00614481790.482
cartilage developmentGO:00512161400.384
negative regulation of cell motilityGO:2000146610.317
cell adhesionGO:00071553290.316
protein hydroxylationGO:001812640.280
wound healingGO:00420601570.279
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.278
cellular response to growth factor stimulusGO:00713631970.272
negative regulation of cell migrationGO:0030336590.240
regulation of integrin mediated signaling pathwayGO:200104480.223
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.217
sensory organ morphogenesisGO:00905962420.203
Mouse
embryonic organ morphogenesisGO:00485622760.180
regulation of cell adhesionGO:00301551540.178
skeletal system morphogenesisGO:00487052030.173
extracellular fibril organizationGO:004320620.173
negative regulation of cell adhesionGO:0007162450.162
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.159
chondrocyte differentiationGO:0002062720.153
collagen fibril organizationGO:0030199320.150
response to amino acidGO:0043200370.139
cell matrix adhesionGO:0007160680.138
regulation of cell motilityGO:20001452360.137
skeletal system developmentGO:00015013560.135
response to growth factorGO:00708481980.132
negative regulation of phagocytosisGO:005076540.131
tissue homeostasisGO:00018941150.129
response to transforming growth factor betaGO:0071559880.128
cellular response to acid chemicalGO:0071229680.127
regulation of cell migrationGO:00303342190.124
respiratory tube developmentGO:00303231670.124
cerebral cortex developmentGO:0021987860.111
regulation of peptidase activityGO:0052547960.109
Human
muscle tissue developmentGO:00605373080.105
negative regulation of tooth mineralizationGO:007017110.104
chondrocyte developmentGO:0002063240.104
anatomical structure homeostasisGO:00602491450.104
response to inorganic substanceGO:0010035960.102
limb morphogenesisGO:00351081490.096
deltoid tuberosity developmentGO:003599330.096
bone morphogenesisGO:0060349780.096
regulation of removal of superoxide radicalsGO:200012140.093
response to organic cyclic compoundGO:00140701980.093
protein trimerizationGO:0070206130.093
blood vessel morphogenesisGO:00485142850.092
cellular response to transforming growth factor beta stimulusGO:0071560880.088
negative regulation of apoptotic signaling pathwayGO:20012341040.087
cellular response to amino acid stimulusGO:0071230290.085
peptidyl amino acid modificationGO:00181933360.085
biomineral tissue developmentGO:0031214640.084
peptidyl proline hydroxylationGO:001951130.083
forebrain developmentGO:00309003020.082
entry into cell of other organism involved in symbiotic interactionGO:0051806150.082
molting cycleGO:0042303900.082
regulation of proteolysisGO:00301621640.081
Human
elastic fiber assemblyGO:004825140.080
response to organonitrogen compoundGO:00102432460.075
lung developmentGO:00303241640.074
respiratory system developmentGO:00605411900.073
fibril organizationGO:009743520.071
response to oxidative stressGO:00069791230.070
regulation of apoptotic signaling pathwayGO:20012331970.069
negative regulation of ossificationGO:0030279490.069
regulation of cell morphogenesis involved in differentiationGO:00107691510.068
extrinsic apoptotic signaling pathwayGO:00971911260.067
regulation of cell sizeGO:0008361720.065
positive regulation of cell substrate adhesionGO:0010811470.064
regulation of cellular response to oxidative stressGO:1900407190.063
regulation of anatomical structure sizeGO:00900661780.063
small gtpase mediated signal transductionGO:0007264970.063
transforming growth factor beta receptor signaling pathwayGO:0007179710.063
response to acid chemicalGO:00011011110.063
positive regulation of neuron projection developmentGO:0010976790.061
reactive oxygen species metabolic processGO:0072593840.060
cellular modified amino acid metabolic processGO:0006575630.060
regulation of epithelial cell proliferationGO:00506781410.059
regulation of hormone levelsGO:00108172110.057
positive regulation of nervous system developmentGO:00519622210.057
developmental growth involved in morphogenesisGO:00605601380.057
negative regulation of viral entry into host cellGO:0046597100.056
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.056
ear developmentGO:00435832000.055
insulin processingGO:003007020.054
sensory perception of soundGO:0007605970.054
negative regulation of cell proliferationGO:00082852960.053
acetylcholine transportGO:001587020.053
circulatory system processGO:00030131970.053
monocarboxylic acid metabolic processGO:00327871910.052
striated muscle tissue developmentGO:00147062930.052
digestive system developmentGO:00551232000.050
regulation of bone mineralizationGO:0030500310.050
membrane raft assemblyGO:000176530.050
head morphogenesisGO:0060323340.049
glycoprotein metabolic processGO:00091001160.049
cell growthGO:00160491300.049
negative regulation of intracellular signal transductionGO:19025321670.048
cellular response to dna damage stimulusGO:00069742070.046
regulation of biomineral tissue developmentGO:0070167330.045
otic vesicle developmentGO:0071599140.045
negative regulation of protein metabolic processGO:00512482820.045
sensory perceptionGO:00076002450.044
Mouse
inner ear morphogenesisGO:00424721010.043
digestive tract developmentGO:00485651900.043
apoptotic signaling pathwayGO:00971903060.043
protein oligomerizationGO:0051259670.042
positive regulation of cellular amino acid metabolic processGO:004576430.042
regulation of cellular response to stressGO:00801351590.042
regulation of reactive oxygen species metabolic processGO:2000377400.042
positive regulation of cell developmentGO:00107202370.042
urogenital system developmentGO:00016552610.041
protein heterooligomerizationGO:0051291140.041
retinal blood vessel morphogenesisGO:006130430.039
regulation of cellular amine metabolic processGO:0033238200.039
metanephric glomerular visceral epithelial cell developmentGO:007224920.038
protein localization to organelleGO:00333651850.038
protein maturationGO:00516041760.037
gland developmentGO:00487323300.037
skin morphogenesisGO:0043589380.037
regulation of response to oxidative stressGO:1902882190.037
regulation of tooth mineralizationGO:007017020.037
cytoplasmic transportGO:00164822340.037
cellular response to abiotic stimulusGO:0071214560.036
integrin mediated signaling pathwayGO:0007229270.036
cartilage development involved in endochondral bone morphogenesisGO:0060351240.036
epithelial cell developmentGO:00020641590.035
collagen biosynthetic processGO:003296470.035
multicellular organismal macromolecule metabolic processGO:0044259190.035
cellular response to superoxideGO:0071451140.035
oxidation reduction processGO:00551143420.034
hormone secretionGO:00468791280.034
skeletal muscle organ developmentGO:00605381630.034
insulin metabolic processGO:190114230.034
regulation of ossificationGO:00302781120.033
endomembrane system organizationGO:00102561470.033
cellular lipid metabolic processGO:00442553230.032
glycerolipid metabolic processGO:00464861220.032
negative regulation of neuron apoptotic processGO:0043524920.032
endochondral bone morphogenesisGO:0060350500.032
palate developmentGO:0060021760.031
multi multicellular organism processGO:00447061090.031
cardiac ventricle morphogenesisGO:0003208500.031
response to bmpGO:0071772140.031
vegf activated neuropilin signaling pathwayGO:003819020.030
skin developmentGO:00435882200.030
cellular response to organonitrogen compoundGO:00714171450.030
response to catecholamineGO:007186940.030
epidermis developmentGO:00085441870.029
negative regulation of immune system processGO:00026832090.029
growth plate cartilage developmentGO:0003417140.029
mitotic cell cycle processGO:19030471590.028
sensory perception of mechanical stimulusGO:00509541070.028
positive regulation of axon extensionGO:0045773200.028
vegf activated neuropilin signaling pathway involved in axon guidanceGO:190237810.028
chondroitin sulfate metabolic processGO:0030204170.028
regulation of rho protein signal transductionGO:0035023710.027
regulation of bone remodelingGO:0046850280.027
hair cycleGO:0042633900.027
cellular ketone metabolic processGO:0042180840.027
rho protein signal transductionGO:0007266320.027
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512260.027
cardiac chamber developmentGO:00032051080.026
odontogenesisGO:0042476780.026
carbohydrate metabolic processGO:00059752300.026
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.026
negative regulation of epithelial cell proliferationGO:0050680640.026
positive regulation of metanephric mesenchymal cell migrationGO:200059110.026
innate immune responseGO:00450871570.026
regulation of erk1 and erk2 cascadeGO:0070372710.025
peptide cross linkingGO:0018149100.025
cardiac muscle tissue morphogenesisGO:0055008440.025
wound healing spreading of cellsGO:004431980.025
positive regulation of cell projection organizationGO:0031346950.025
positive regulation of cell adhesionGO:0045785800.025
negative regulation of gastrulationGO:200054230.024
regulation of angiogenesisGO:0045765810.024
formation of primary germ layerGO:0001704770.024
bone mineralizationGO:0030282540.024
entry into other organism involved in symbiotic interactionGO:0051828150.024
bmp signaling pathwayGO:0030509930.024
regulation of protein bindingGO:0043393600.024
positive regulation of neuron differentiationGO:00456661410.023
transcription initiation from rna polymerase i promoterGO:000636140.023
response to nutrient levelsGO:00316671090.023
regulation of protein kinase b signalingGO:0051896560.023
regulation of cellular component sizeGO:00325351210.023
regulation of ras protein signal transductionGO:00465781140.023
cellular response to bmp stimulusGO:0071773140.022
peptide cross linking via chondroitin 4 sulfate glycosaminoglycanGO:001980080.022
movement in environment of other organism involved in symbiotic interactionGO:0052192150.022
gastrulationGO:00073691160.022
endoderm formationGO:0001706200.021
collagen metabolic processGO:0032963170.021
response to radiationGO:00093141650.021
pallium developmentGO:00215431200.021
negative regulation of signal transduction in absence of ligandGO:1901099160.021
response to metal ionGO:0010038470.021
kidney developmentGO:00018222130.021
acetate ester transportGO:190137420.021
interspecies interaction between organismsGO:0044419830.021
mitotic cell cycleGO:00002781950.021
negative regulation of odontogenesisGO:004248330.021
negative regulation of biomineral tissue developmentGO:0070168110.021
cellular response to oxidative stressGO:0034599760.020
regulation of smad protein import into nucleusGO:006039030.020
protein processingGO:00164851630.020
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.020
early endosome to late endosome transportGO:004502220.020
ras protein signal transductionGO:0007265770.020
protein localization to membraneGO:00726571080.020
superoxide metabolic processGO:0006801270.019
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001240160.019
negative regulation of cellular protein metabolic processGO:00322692470.019
negative regulation of molecular functionGO:00440922580.019
regulation of macrophage migration inhibitory factor signaling pathwayGO:200044610.019
regulation of system processGO:00440572000.019
actin cytoskeleton organizationGO:00300362200.019
movement in host environmentGO:0052126150.019
replacement ossificationGO:0036075260.018
regulation of neuron migrationGO:2001222220.018
cell type specific apoptotic processGO:00972852680.018
positive regulation of cell growthGO:0030307330.018
nitrogen compound transportGO:00717052710.018
antimicrobial peptide secretionGO:000277610.018
regionalizationGO:00030023370.018
response to monosaccharideGO:0034284670.018
response to decreased oxygen levelsGO:0036293590.018
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.018
negative regulation of neuron deathGO:1901215980.018
entry into hostGO:0044409150.018
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001239260.018
cardiac chamber morphogenesisGO:0003206930.017
neuromuscular processGO:0050905990.017
regulation of phospholipid biosynthetic processGO:007107130.017
negative regulation of dna replicationGO:000815640.017
forebrain cell migrationGO:0021885580.017
ear morphogenesisGO:00424711180.017
neuron projection extensionGO:1990138640.017
hair follicle developmentGO:0001942850.017
bone trabecula formationGO:006034690.017
cardiac muscle tissue developmentGO:00487381300.017
digestive tract morphogenesisGO:00485461470.017
regulation of cell growthGO:0001558910.017
regulation of cellular ketone metabolic processGO:0010565660.017
negative regulation of blood vessel morphogenesisGO:2000181250.017
regulation of extent of cell growthGO:0061387520.017
monosaccharide transportGO:0015749580.017
cellular amide metabolic processGO:0043603580.016
plasma membrane organizationGO:0007009900.016
response to superoxideGO:0000303160.016
negative regulation of multi organism processGO:0043901680.016
peptidyl proline modificationGO:001820860.016
type b pancreatic cell proliferationGO:0044342100.016
regulation of protein targetingGO:1903533610.016
cellular amino acid metabolic processGO:00065201030.016
intracellular protein transportGO:00068862040.016
tissue remodelingGO:00487711020.016
developmental cell growthGO:0048588840.016
endothelial cell migrationGO:0043542440.016
ventricular cardiac muscle tissue morphogenesisGO:0055010320.016
signal transduction in absence of ligandGO:0038034550.016
activation of immune responseGO:00022531380.015
prostate gland morphogenesisGO:0060512320.015
mesenchymal cell developmentGO:0014031930.015
telencephalon developmentGO:00215371860.015
response to reactive oxygen speciesGO:0000302560.015
regulation of reactive oxygen species biosynthetic processGO:190342620.015
multicellular organismal metabolic processGO:0044236280.015
negative regulation of cell substrate adhesionGO:0010812160.015
face morphogenesisGO:0060325290.015
regulation of vesicle mediated transportGO:00606271390.015
muscle tissue morphogenesisGO:0060415530.015
multicellular organismal homeostasisGO:00488711640.015
regulation of mapk cascadeGO:00434082480.015
intrinsic apoptotic signaling pathwayGO:00971931320.015
metanephric glomerular epithelium developmentGO:007224430.015
mapk cascadeGO:00001652810.014
sensory perception of light stimulusGO:0050953540.014
Mouse
regulation of chondrocyte differentiationGO:0032330330.014
purine ribonucleoside triphosphate catabolic processGO:00092071990.014
negative regulation of macrophage chemotaxisGO:001076010.014
negative regulation of complement activationGO:004591630.014
establishment or maintenance of apical basal cell polarityGO:0035088210.014
negative regulation of proteolysisGO:0045861740.014
protein localization to plasma membraneGO:0072659570.014
positive regulation of ras protein signal transductionGO:0046579130.014
termination of rna polymerase i transcriptionGO:000636320.014
negative regulation of protein activation cascadeGO:200025830.014
peripheral nervous system axon regenerationGO:001401220.014
cytokine mediated signaling pathwayGO:00192211150.014
epithelial cell proliferationGO:00506731740.013
positive regulation of protein modification processGO:00314012990.013
regulation of transmission of nerve impulseGO:005196910.013
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.013
cellular response to external stimulusGO:0071496880.013
negative regulation of endothelial cell proliferationGO:000193780.013
smooth muscle tissue developmentGO:0048745220.013
blood circulationGO:00080151950.013
protein heterotrimerizationGO:007020880.013
cellular response to oxygen radicalGO:0071450140.013
positive regulation of erk1 and erk2 cascadeGO:0070374470.013
tendon formationGO:003599240.013
removal of superoxide radicalsGO:0019430120.013
ovulation cycleGO:0042698590.013
wnt signaling pathwayGO:00160551880.013
regulation of organelle organizationGO:00330432890.013
symbiosis encompassing mutualism through parasitismGO:0044403830.013
regulation of neuron projection developmentGO:00109751690.012
astrocyte fate commitmentGO:006001840.012
protein targetingGO:00066051430.012
aminoglycan metabolic processGO:0006022340.012
cellular component assembly involved in morphogenesisGO:00109271390.012
ameboidal type cell migrationGO:00016671280.012
vacuole organizationGO:0007033380.012
proteoglycan metabolic processGO:0006029380.012
negative regulation of phosphorylationGO:00423261660.012
regulation of body fluid levelsGO:00508781620.012
canonical wnt signaling pathwayGO:00600701300.012
epithelial tube morphogenesisGO:00605623030.012
response to steroid hormoneGO:0048545560.012
entry into host cellGO:0030260150.012
glycerophospholipid metabolic processGO:0006650710.012
positive regulation of growthGO:00459271040.012
regulation of cyclic nucleotide metabolic processGO:0030799400.012
appendage morphogenesisGO:00351071490.012
cellular response to thyroid hormone stimulusGO:009706710.012
negative regulation of peptidase activityGO:0010466460.012
renal system developmentGO:00720012250.012
developmental maturationGO:00217001930.012
dna metabolic processGO:00062593030.012
cell junction organizationGO:0034330770.012
glycosaminoglycan metabolic processGO:0030203340.012
carbohydrate homeostasisGO:00335001280.012
negative regulation of cellular component organizationGO:00511291940.012
reactive nitrogen species metabolic processGO:200105700.012
response to extracellular stimulusGO:00099911270.011
peptide secretionGO:00027901140.011
regulation of vasculature developmentGO:1901342880.011
acetylcholine secretion neurotransmissionGO:001405520.011
humoral immune responseGO:0006959570.011
regulation of map kinase activityGO:00434051200.011
negative regulation of toll signaling pathwayGO:004575110.011
embryonic skeletal system morphogenesisGO:0048704910.011
cell aggregationGO:0098743180.011
spermatogenesisGO:00072832840.011
regulation of protein processingGO:0070613960.011
peptide transportGO:00158331330.011
tissue migrationGO:0090130680.011
organonitrogen compound biosynthetic processGO:19015661920.011
negative regulation of hydrolase activityGO:0051346710.011
multicellular organismal catabolic processGO:004424370.011
chemotaxisGO:00069352470.011
heart morphogenesisGO:00030071780.011
lipid biosynthetic processGO:00086101790.011
telencephalon cell migrationGO:0022029550.011
negative regulation of endocytosisGO:0045806120.011
fatty acid metabolic processGO:00066311210.011
i kappab kinase nf kappab signalingGO:0007249850.011
negative regulation of osteoblast differentiationGO:0045668300.011
regulation of protein maturationGO:1903317960.011
somitogenesisGO:0001756690.011
reactive oxygen species biosynthetic processGO:190340980.011
antibacterial peptide secretionGO:000277910.011
otolith morphogenesisGO:003247430.011
nuclear importGO:0051170950.011
regulation of cell cycle processGO:00105641600.010
immune effector processGO:00022523210.010
negative regulation of cell developmentGO:00107211690.010
negative regulation of cell growthGO:0030308440.010
integrin biosynthetic processGO:004511210.010
antibacterial peptide biosynthetic processGO:000278020.010
appendage developmentGO:00487361660.010
regulation of stem cell proliferationGO:0072091780.010
negative regulation of peroxisome proliferator activated receptor signaling pathwayGO:003535930.010
regulation of cellular amino acid metabolic processGO:000652150.010
positive regulation of retinal ganglion cell axon guidanceGO:190233620.010
positive regulation of nucleocytoplasmic transportGO:0046824300.010
cellular response to vitaminGO:007129520.010
negative regulation of bmp signaling pathwayGO:0030514350.010
notch signaling pathwayGO:0007219710.010
negative regulation of cartilage developmentGO:0061037170.010

Pcolce disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.833
musculoskeletal system diseaseDOID:1700.833
connective tissue diseaseDOID:6500.668
bone development diseaseDOID:008000600.457
bone diseaseDOID:008000100.457
muscular diseaseDOID:008000000.311
muscle tissue diseaseDOID:6600.311
myopathyDOID:42300.311
collagen diseaseDOID:85400.192
osteochondrodysplasiaDOID:225600.177
bone remodeling diseaseDOID:008000500.126
muscular dystrophyDOID:988400.048
nervous system diseaseDOID:86300.046
eye diseaseDOID:561400.046
sensory system diseaseDOID:005015500.046
eye and adnexa diseaseDOID:149200.046
congenital muscular dystrophyDOID:005055700.040
ehlers danlos syndromeDOID:1335900.031
retinal diseaseDOID:567900.028
retinal degenerationDOID:846600.028
bone resorption diseaseDOID:008001100.025
osteoporosisDOID:1147600.025
immune system diseaseDOID:291400.018
charcot marie tooth diseaseDOID:1059500.017
neuromuscular diseaseDOID:44000.017
neuropathyDOID:87000.017
osteogenesis imperfectaDOID:1234700.012
glaucomaDOID:168600.012