Mus musculus

0 known processes

Ibtk

inhibitor of Bruton agammaglobulinemia tyrosine kinase

(Aliases: mKIAA1417,BTKI,5430411K16Rik,AA409502)

Ibtk biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
proteolysis involved in cellular protein catabolic processGO:00516031470.156
modification dependent macromolecule catabolic processGO:00436321330.084
cellular protein catabolic processGO:00442571550.073
cellular amine metabolic processGO:0044106440.061
ubiquitin dependent protein catabolic processGO:00065111290.059
chromatin organizationGO:00063252060.056
protein ubiquitinationGO:00165671710.054
cellular amino acid metabolic processGO:00065201030.054
protein catabolic processGO:00301632210.053
cellular macromolecule catabolic processGO:00442652060.048
cellular response to dna damage stimulusGO:00069742070.043
male gamete generationGO:00482322850.042
negative regulation of protein metabolic processGO:00512482820.041
Human
lateral inhibitionGO:004633110.040
macromolecule catabolic processGO:00090572810.039
negative regulation of intracellular signal transductionGO:19025321670.038
amine metabolic processGO:0009308450.036
fertilizationGO:00095661270.036
organelle localizationGO:00516401790.035
regulation of organelle organizationGO:00330432890.033
modification dependent protein catabolic processGO:00199411330.033
chromatin modificationGO:00165681870.032
histone modificationGO:00165701590.032
peptidyl amino acid modificationGO:00181933360.032
Human
purine ribonucleoside catabolic processGO:00461302050.031
glycoprotein biosynthetic processGO:0009101890.031
purine ribonucleotide catabolic processGO:00091542080.031
protein modification by small protein conjugationGO:00324461870.031
endomembrane system organizationGO:00102561470.030
innate immune responseGO:00450871570.030
cellular response to cytokine stimulusGO:00713451890.029
ras protein signal transductionGO:0007265770.029
membrane organizationGO:00610242450.029
regulation of cellular amine metabolic processGO:0033238200.028
small gtpase mediated signal transductionGO:0007264970.028
compound eye developmentGO:004874910.027
regulation of hydrolase activityGO:00513362460.027
carbohydrate derivative biosynthetic processGO:19011371830.027
regulation of cellular amino acid metabolic processGO:000652150.026
protein polyubiquitinationGO:0000209330.026
cellular ketone metabolic processGO:0042180840.026
glycosyl compound metabolic processGO:19016572460.025
purine nucleotide metabolic processGO:00061633020.025
nucleobase containing small molecule metabolic processGO:00550863520.025
nucleotide metabolic processGO:00091173320.024
purine ribonucleoside triphosphate catabolic processGO:00092071990.024
spermatogenesisGO:00072832840.023
mitotic cell cycleGO:00002781950.023
ribonucleotide metabolic processGO:00092592910.023
organophosphate catabolic processGO:00464342320.023
nucleoside metabolic processGO:00091162460.023
ribose phosphate metabolic processGO:00196932910.022
maintenance of locationGO:0051235890.022
Human
nucleoside phosphate catabolic processGO:19012922220.022
ribonucleoside triphosphate metabolic processGO:00091992200.022
ribonucleoside metabolic processGO:00091192450.022
negative regulation of molecular functionGO:00440922580.022
Human
glycoprotein metabolic processGO:00091001160.021
nucleoside catabolic processGO:00091642060.021
regulation of apoptotic signaling pathwayGO:20012331970.021
regulation of cellular component biogenesisGO:00440871810.021
proteasomal protein catabolic processGO:0010498980.021
ribonucleoside catabolic processGO:00424542060.021
purine ribonucleoside metabolic processGO:00461282410.021
negative regulation of immune system processGO:00026832090.021
regulation of protein localizationGO:00328802310.021
translationGO:0006412930.021
posttranscriptional regulation of gene expressionGO:00106081550.021
cation transportGO:00068123990.021
Human
regulation of translationGO:0006417710.020
organelle fissionGO:00482851700.020
regulation of cellular catabolic processGO:00313292420.020
nucleoside phosphate metabolic processGO:00067533380.020
aromatic compound catabolic processGO:00194392860.020
protein localization to membraneGO:00726571080.020
organonitrogen compound catabolic processGO:19015652640.020
cytokine productionGO:00018163190.020
negative regulation of cell proliferationGO:00082852960.019
gland developmentGO:00487323300.019
purine nucleoside metabolic processGO:00422782410.019
localization within membraneGO:005166840.019
regulation of cell activationGO:00508652890.019
forebrain developmentGO:00309003020.019
covalent chromatin modificationGO:00165691630.019
positive regulation of cellular catabolic processGO:00313311480.019
regulation of proteolysisGO:00301621640.018
purine ribonucleotide metabolic processGO:00091502900.018
apoptotic signaling pathwayGO:00971903060.018
gtp catabolic processGO:00061841430.018
regulation of secretionGO:00510462740.018
rhythmic processGO:00485111740.018
purine containing compound metabolic processGO:00725213110.018
cellular nitrogen compound catabolic processGO:00442702800.018
regionalizationGO:00030023370.018
multicellular organismal homeostasisGO:00488711640.018
single organism cell adhesionGO:00986021560.018
carbohydrate derivative catabolic processGO:19011362310.017
positive regulation of cellular amino acid metabolic processGO:004576430.017
cellular homeostasisGO:00197252400.017
Human
dna repairGO:00062811070.017
cellular response to molecule of bacterial originGO:0071219830.017
hematopoietic progenitor cell differentiationGO:00022441430.017
organic cyclic compound catabolic processGO:19013612950.017
protein maturationGO:00516041760.017
establishment of organelle localizationGO:00516561220.016
mitochondrion organizationGO:00070051340.016
response to lipopolysaccharideGO:00324961280.016
regulation of cellular ketone metabolic processGO:0010565660.016
positive regulation of cellular amine metabolic processGO:003324050.016
response to organonitrogen compoundGO:00102432460.016
negative regulation of cellular component organizationGO:00511291940.016
purine nucleoside catabolic processGO:00061522050.016
negative regulation of cellular protein metabolic processGO:00322692470.016
Human
regulation of cell cycleGO:00517262810.016
glycosyl compound catabolic processGO:19016582060.016
rho protein signal transductionGO:0007266320.016
ossificationGO:00015032160.016
protein localization to organelleGO:00333651850.015
cation transmembrane transportGO:00986552660.015
vesicle organizationGO:0016050600.015
homeostasis of number of cellsGO:00488722100.015
regulation of cytokine productionGO:00018172660.015
cellular response to biotic stimulusGO:0071216920.015
actin cytoskeleton organizationGO:00300362200.015
t cell activationGO:00421102890.015
regulation of ion transportGO:00432692150.015
protein processingGO:00164851630.015
nucleoside triphosphate metabolic processGO:00091412300.015
purine nucleotide catabolic processGO:00061952110.015
response to oxidative stressGO:00069791230.015
cellularizationGO:000734910.015
purine nucleoside triphosphate metabolic processGO:00091442260.015
guanosine containing compound metabolic processGO:19010681440.015
regulation of cell cycle processGO:00105641600.015
nucleoside triphosphate catabolic processGO:00091432050.015
cellular response to lipidGO:00713961450.015
tissue homeostasisGO:00018941150.014
protein modification by small protein conjugation or removalGO:00706472070.014
leukocyte differentiationGO:00025213420.014
regulation of ras protein signal transductionGO:00465781140.014
gonad developmentGO:00084061410.014
macromolecule glycosylationGO:0043413550.014
protein secretionGO:00093061110.014
cytokinetic processGO:003250620.014
myeloid cell homeostasisGO:00022621140.014
negative regulation of phosphorus metabolic processGO:00105631840.014
Human
regulation of chromosome organizationGO:0033044830.014
response to molecule of bacterial originGO:00022371430.014
positive regulation of protein modification processGO:00314012990.014
regulation of secretion by cellGO:19035302490.014
cellular response to growth factor stimulusGO:00713631970.013
mitotic cell cycle processGO:19030471590.013
positive regulation of apoptotic processGO:00430652170.013
regulation of establishment of protein localizationGO:00702011810.013
mitochondrion distributionGO:004831140.013
regulation of protein catabolic processGO:00421761080.013
oxidation reduction processGO:00551143420.013
ribonucleotide catabolic processGO:00092612080.013
actin filament organizationGO:00070151130.013
plasma membrane organizationGO:0007009900.013
purine containing compound catabolic processGO:00725232130.013
carbohydrate metabolic processGO:00059752300.013
regulation of chromosome segregationGO:0051983210.013
germ cell developmentGO:00072811850.013
cell adhesionGO:00071553290.013
positive regulation of hydrolase activityGO:00513451480.013
cation homeostasisGO:00550802120.013
Human
divalent metal ion transportGO:00708381720.013
Human
positive regulation of cell deathGO:00109422240.013
muscle tissue developmentGO:00605373080.013
mitotic nuclear divisionGO:0007067480.013
intrinsic apoptotic signaling pathwayGO:00971931320.013
carbohydrate homeostasisGO:00335001280.013
protein glycosylationGO:0006486550.012
spermatid differentiationGO:00485151150.012
intracellular protein transportGO:00068862040.012
immune effector processGO:00022523210.012
guanosine containing compound catabolic processGO:19010691440.012
negative regulation of phosphate metabolic processGO:00459361840.012
Human
response to growth factorGO:00708481980.012
meiosis iGO:0007127600.012
male meiosis iGO:0007141160.012
cytoplasmic transportGO:00164822340.012
Human
regulation of protein complex assemblyGO:0043254830.012
copii coated vesicle buddingGO:009011420.012
placenta developmentGO:00018901400.012
nucleotide catabolic processGO:00091662170.012
purine ribonucleoside triphosphate metabolic processGO:00092052200.012
cellular protein complex assemblyGO:00436231160.012
positive regulation of programmed cell deathGO:00430682180.012
dna metabolic processGO:00062593030.012
transmembrane transportGO:00550854120.012
single fertilizationGO:0007338820.012
stem cell differentiationGO:00488632680.012
wound healingGO:00420601570.012
spermatid developmentGO:00072861080.012
telencephalon developmentGO:00215371860.012
regulation of protein transportGO:00512231630.012
nitrogen compound transportGO:00717052710.012
myeloid cell differentiationGO:00300992330.011
gtp metabolic processGO:00460391440.011
response to inorganic substanceGO:0010035960.011
positive regulation of cell activationGO:00508671580.011
inflammatory responseGO:00069542440.011
regulation of cellular response to stressGO:00801351590.011
response to acid chemicalGO:00011011110.011
regulation of mitotic cell cycleGO:00073461260.011
epithelial cell developmentGO:00020641590.011
negative regulation of protein modification processGO:00314001630.011
Human
rna interferenceGO:001624620.011
nuclear divisionGO:00002801580.011
regulation of leukocyte differentiationGO:19021051590.011
regulation of lymphocyte activationGO:00512492400.011
regulation of membrane potentialGO:00423911920.011
anatomical structure homeostasisGO:00602491450.011
blastocyst developmentGO:0001824800.011
microtubule cytoskeleton organizationGO:00002261570.011
positive regulation of secretionGO:00510471300.011
regulation of hormone levelsGO:00108172110.011
regulation of cell projection organizationGO:00313442060.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.011
positive regulation of organelle organizationGO:00106381280.011
negative regulation of phosphorylationGO:00423261660.011
Human
meiotic cell cycle processGO:1903046770.011
positive regulation of nervous system developmentGO:00519622210.011
cellular chemical homeostasisGO:00550822150.011
Human
regulation of cell divisionGO:0051302760.011
multi multicellular organism processGO:00447061090.011
regulation of multi organism processGO:00439001110.011
cellular response to lipopolysaccharideGO:0071222770.011
cellular lipid metabolic processGO:00442553230.011
single organismal cell cell adhesionGO:00163371310.010
response to nutrient levelsGO:00316671090.010
regulation of neuron differentiationGO:00456642810.010
organic hydroxy compound metabolic processGO:19016152030.010
regulation of defense responseGO:00313472330.010
ion transmembrane transportGO:00342203610.010
positive regulation of lymphocyte activationGO:00512511400.010
cell divisionGO:00513011200.010
ribonucleoside monophosphate metabolic processGO:0009161800.010
peptidyl tyrosine modificationGO:00182121450.010
Human
female gamete generationGO:0007292740.010
negative regulation of cellular amino acid metabolic processGO:004576300.010
anion transportGO:00068201770.010
heterocycle catabolic processGO:00467002800.010
negative regulation of synapse assemblyGO:005196430.010
mitotic sister chromatid separationGO:005130690.010
calcium ion transportGO:00068161590.010
Human
regulation of response to woundingGO:19030341890.010

Ibtk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.034
nervous system diseaseDOID:86300.034
musculoskeletal system diseaseDOID:1700.016
central nervous system diseaseDOID:33100.015
neurodegenerative diseaseDOID:128900.015
sensory system diseaseDOID:005015500.011
disease of cellular proliferationDOID:1456600.010
immune system diseaseDOID:291400.010