Mus musculus

10 known processes

Cul2

cullin 2

(Aliases: 1300003D18Rik,AI327301,KIAA4106,mKIAA4106,4932411N15Rik)

Cul2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
proteolysis involved in cellular protein catabolic processGO:00516031470.387
protein modification by small protein conjugation or removalGO:00706472070.247
protein catabolic processGO:00301632210.207
dna metabolic processGO:00062593030.194
macromolecule catabolic processGO:00090572810.180
microtubule based processGO:00070172360.157
modification dependent protein catabolic processGO:00199411330.156
cellular protein catabolic processGO:00442571550.151
proteasomal protein catabolic processGO:0010498980.146
translationGO:0006412930.142
ubiquitin dependent protein catabolic processGO:00065111290.128
protein modification by small protein removalGO:0070646210.097
cellular macromolecule catabolic processGO:00442652060.095
nucleic acid phosphodiester bond hydrolysisGO:0090305490.086
dna repairGO:00062811070.076
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.064
modification dependent macromolecule catabolic processGO:00436321330.061
synaptic transmissionGO:00072683290.060
Fly
cytoplasmic transportGO:00164822340.055
ribose phosphate metabolic processGO:00196932910.049
protein localization to organelleGO:00333651850.049
cellular amino acid metabolic processGO:00065201030.049
mitotic cell cycle processGO:19030471590.047
regulation of organelle organizationGO:00330432890.047
protein targetingGO:00066051430.045
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.045
regulation of cellular catabolic processGO:00313292420.041
protein polyubiquitinationGO:0000209330.038
protein modification by small protein conjugationGO:00324461870.038
nucleoside metabolic processGO:00091162460.038
synapse organizationGO:00508081250.037
Fly
ribonucleoside triphosphate catabolic processGO:00092031990.037
purine nucleoside catabolic processGO:00061522050.036
regulation of protein localizationGO:00328802310.034
posttranscriptional regulation of gene expressionGO:00106081550.033
trna metabolic processGO:0006399110.033
purine ribonucleotide metabolic processGO:00091502900.033
nucleoside monophosphate catabolic processGO:0009125590.032
cellular response to dna damage stimulusGO:00069742070.031
trna processingGO:0008033110.031
male gamete generationGO:00482322850.030
mitochondrial transportGO:0006839360.030
transmembrane transportGO:00550854120.030
negative regulation of wnt signaling pathwayGO:0030178730.029
negative regulation of cell proliferationGO:00082852960.029
compound eye developmentGO:004874910.029
heterocycle catabolic processGO:00467002800.029
response to oxidative stressGO:00069791230.028
endocytosisGO:00068971680.028
organelle fissionGO:00482851700.028
regulation of protein catabolic processGO:00421761080.028
organophosphate catabolic processGO:00464342320.027
membrane organizationGO:00610242450.027
regulation of ion transportGO:00432692150.027
establishment of protein localization to organelleGO:00725941180.026
regulation of cell cycleGO:00517262810.026
purine nucleoside triphosphate catabolic processGO:00091462030.026
locomotory behaviorGO:00076261950.026
chromatin organizationGO:00063252060.025
negative regulation of cell developmentGO:00107211690.025
regulation of membrane potentialGO:00423911920.025
nucleoside phosphate catabolic processGO:19012922220.025
protein ubiquitinationGO:00165671710.025
lateral inhibitionGO:004633110.025
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436230.025
microtubule cytoskeleton organizationGO:00002261570.024
mesenchyme developmentGO:00604851520.024
cellular nitrogen compound catabolic processGO:00442702800.024
organelle assemblyGO:00709251770.024
intracellular protein transportGO:00068862040.024
regulation of proteolysisGO:00301621640.023
organic cyclic compound catabolic processGO:19013612950.023
purine containing compound catabolic processGO:00725232130.023
maintenance of locationGO:0051235890.022
regulation of mitochondrial fissionGO:009014030.022
purine ribonucleoside catabolic processGO:00461302050.022
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.022
aromatic compound catabolic processGO:00194392860.022
ribonucleoside triphosphate metabolic processGO:00091992200.022
positive regulation of cellular catabolic processGO:00313311480.022
mitotic cell cycleGO:00002781950.022
positive regulation of dna templated transcription elongationGO:003278620.021
neuron apoptotic processGO:00514021420.021
protein polymerizationGO:0051258570.021
positive regulation of proteolysisGO:0045862850.021
spermatogenesisGO:00072832840.020
response to light stimulusGO:00094161350.020
regulation of secretionGO:00510462740.020
ion transmembrane transportGO:00342203610.020
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.020
muscle cell differentiationGO:00426922610.020
lipid localizationGO:00108761260.020
regulation of establishment of protein localizationGO:00702011810.019
multi multicellular organism processGO:00447061090.019
organonitrogen compound catabolic processGO:19015652640.019
cellular response to organonitrogen compoundGO:00714171450.019
nuclear transportGO:00511691390.019
protein deubiquitinationGO:0016579190.019
inflammatory responseGO:00069542440.019
cell divisionGO:00513011200.018
nitrogen compound transportGO:00717052710.018
protein importGO:00170381010.018
nucleocytoplasmic transportGO:00069131390.018
neuron deathGO:00709971540.018
regulation of translationGO:0006417710.018
mitochondrial translationGO:003254340.018
purine nucleoside triphosphate metabolic processGO:00091442260.018
trna wobble base modificationGO:000209720.017
ncrna processingGO:0034470260.017
stem cell developmentGO:00488642190.017
germ cell developmentGO:00072811850.017
Fly
cellular homeostasisGO:00197252400.017
nuclear divisionGO:00002801580.017
purine ribonucleoside metabolic processGO:00461282410.017
cation transportGO:00068123990.017
negative regulation of cellular component organizationGO:00511291940.017
regulation of cellular component biogenesisGO:00440871810.016
Fly
cellular response to hormone stimulusGO:00328701500.016
organelle localizationGO:00516401790.016
rna phosphodiester bond hydrolysis exonucleolyticGO:009050340.016
regulation of cell migrationGO:00303342190.016
purine containing compound metabolic processGO:00725213110.016
wnt signaling pathwayGO:00160551880.016
regulation of transmembrane transportGO:00347621280.016
nucleoside catabolic processGO:00091642060.016
cellular protein complex assemblyGO:00436231160.016
regulation of vesicle mediated transportGO:00606271390.016
carbohydrate derivative catabolic processGO:19011362310.016
organelle disassemblyGO:190300820.016
chromatin modificationGO:00165681870.016
purine nucleoside metabolic processGO:00422782410.015
nucleoside phosphate metabolic processGO:00067533380.015
nucleoside triphosphate catabolic processGO:00091432050.015
rna processingGO:00063961050.015
double strand break repairGO:0006302480.015
endomembrane system organizationGO:00102561470.015
stem cell differentiationGO:00488632680.014
purine ribonucleoside triphosphate metabolic processGO:00092052200.014
regulation of kinase activityGO:00435492490.014
digestionGO:0007586400.014
regulation of neuron deathGO:19012141340.014
mapk cascadeGO:00001652810.014
canonical wnt signaling pathwayGO:00600701300.014
mirna catabolic processGO:001058720.014
striated muscle myosin thick filament assemblyGO:007168810.014
regulation of cellular protein catabolic processGO:1903362610.014
regulation of cell motilityGO:20001452360.014
glycosyl compound catabolic processGO:19016582060.014
cellular response to peptideGO:1901653920.014
purine ribonucleotide catabolic processGO:00091542080.014
multi organism behaviorGO:0051705620.014
neural tube formationGO:00018411080.014
regulation of synaptic growth at neuromuscular junctionGO:000858240.014
Fly
single fertilizationGO:0007338820.014
purine nucleoside monophosphate metabolic processGO:0009126810.014
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.014
ribonucleotide metabolic processGO:00092592910.014
negative regulation of cell cycleGO:00457861230.013
protein oligomerizationGO:0051259670.013
negative regulation of phosphorus metabolic processGO:00105631840.013
regulation of neuron apoptotic processGO:00435231220.013
snrna metabolic processGO:001607310.013
multicellular organismal protein metabolic processGO:004426820.013
lymphocyte proliferationGO:00466511640.013
regulation of peptidase activityGO:0052547960.013
regulation of defense responseGO:00313472330.013
dna recombinationGO:0006310920.013
purine nucleotide catabolic processGO:00061952110.013
positive regulation of organelle organizationGO:00106381280.013
er associated ubiquitin dependent protein catabolic processGO:0030433100.013
muscle cell developmentGO:00550011330.013
response to organonitrogen compoundGO:00102432460.013
protein complex disassemblyGO:0043241400.012
learning or memoryGO:00076111480.012
nucleoside triphosphate metabolic processGO:00091412300.012
mitochondrion organizationGO:00070051340.012
regulation of cellular amino acid metabolic processGO:000652150.012
cellular component assembly involved in morphogenesisGO:00109271390.012
response to peptideGO:19016521360.012
amine metabolic processGO:0009308450.012
regulation of hydrolase activityGO:00513362460.012
negative regulation of protein phosphorylationGO:00019331260.012
covalent chromatin modificationGO:00165691630.012
negative regulation of phosphate metabolic processGO:00459361840.012
purine nucleoside monophosphate catabolic processGO:0009128580.012
dephosphorylationGO:00163111290.012
negative regulation of protein metabolic processGO:00512482820.012
regulation of ion transmembrane transportGO:00347651190.012
regulation of proteasomal protein catabolic processGO:0061136460.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.012
purine nucleotide metabolic processGO:00061633020.012
negative regulation of protein modification processGO:00314001630.012
ribonucleoside monophosphate metabolic processGO:0009161800.012
nucleotide catabolic processGO:00091662170.012
cation transmembrane transportGO:00986552660.012
negative regulation of intracellular signal transductionGO:19025321670.012
regulation of secretion by cellGO:19035302490.012
trna wobble uridine modificationGO:000209820.012
spermatid differentiationGO:00485151150.012
inorganic cation transmembrane transportGO:00986622070.012
meiotic cell cycle processGO:1903046770.012
regulation of multi organism processGO:00439001110.012
positive regulation of cellular protein catabolic processGO:1903364340.012
regulation of chromosome organizationGO:0033044830.012
skeletal muscle organ developmentGO:00605381630.011
peripheral nervous system developmentGO:0007422530.011
response to organic cyclic compoundGO:00140701980.011
spermatid developmentGO:00072861080.011
regulation of protein complex assemblyGO:0043254830.011
regulation of cellular amine metabolic processGO:0033238200.011
ribonucleoside catabolic processGO:00424542060.011
divalent metal ion transportGO:00708381720.011
histone modificationGO:00165701590.011
multicellular organismal homeostasisGO:00488711640.011
positive regulation of cell deathGO:00109422240.011
atp metabolic processGO:0046034750.011
ribonucleoside metabolic processGO:00091192450.011
mitotic cytokinesisGO:000028140.010
regulation of stem cell differentiationGO:2000736500.010
myosin filament assemblyGO:003103420.010
protein import into nucleusGO:0006606950.010
cellular amine metabolic processGO:0044106440.010
negative regulation of phosphorylationGO:00423261660.010
positive regulation of protein catabolic processGO:0045732600.010
glycosyl compound metabolic processGO:19016572460.010

Cul2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.020
disease of anatomical entityDOID:700.020
neurodegenerative diseaseDOID:128900.014
central nervous system diseaseDOID:33100.014