Mus musculus

488 known processes

P2rx7

purinergic receptor P2X, ligand-gated ion channel, 7

(Aliases: P2X7R,P2X(7),AI467586)

P2rx7 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
defense response to gram positive bacteriumGO:0050830500.893
positive regulation of cytokine productionGO:00018191740.864
immune effector processGO:00022523210.854
regulation of cytokine productionGO:00018172660.772
small gtpase mediated signal transductionGO:0007264970.743
positive regulation of cell activationGO:00508671580.697
inflammatory responseGO:00069542440.673
cytokine mediated signaling pathwayGO:00192211150.645
leukocyte mediated immunityGO:00024431740.643
positive regulation of monocyte chemotaxisGO:009002620.624
leukocyte activation involved in immune responseGO:00023661260.615
helper t cell chemotaxisGO:003570410.607
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188540.602
regulation of eosinophil degranulationGO:004330910.599
immune response activating signal transductionGO:00027571160.564
cytokine productionGO:00018163190.550
positive regulation of defense responseGO:00313491240.538
regulation of monocyte extravasationGO:200043720.507
regulation of cell activationGO:00508652890.500
positive regulation of monocyte extravasationGO:200043910.499
positive regulation of innate immune responseGO:0045089800.489
t cell differentiationGO:00302171740.469
regulation of establishment of protein localizationGO:00702011810.455
defense response to other organismGO:00985421970.453
eosinophil activationGO:004330710.436
cd8 positive alpha beta t cell extravasationGO:003569730.434
alpha beta t cell activationGO:0046631910.431
t cell extravasationGO:007268340.431
positive regulation of adaptive immune responseGO:0002821610.416
extrinsic apoptotic signaling pathwayGO:00971911260.405
multicellular organismal homeostasisGO:00488711640.404
innate immune responseGO:00450871570.402
regulation of adaptive immune responseGO:0002819900.399
defense response to bacteriumGO:00427421190.398
ras protein signal transductionGO:0007265770.391
negative regulation of defense responseGO:0031348770.390
leukocyte differentiationGO:00025213420.378
activation of immune responseGO:00022531380.377
axon guidanceGO:00074111410.371
regulation of defense responseGO:00313472330.369
positive regulation of t cell extravasationGO:200040920.369
positive regulation of lymphocyte activationGO:00512511400.369
cytokine biosynthetic processGO:0042089680.368
positive regulation of t cell receptor signaling pathwayGO:005086240.366
activation of innate immune responseGO:0002218560.365
t helper 17 cell chemotaxisGO:003570510.361
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.355
exocytosisGO:00068871210.355
positive regulation of mapk cascadeGO:00434101700.353
g protein coupled receptor signaling pathwayGO:00071862430.353
calcium mediated signalingGO:0019722460.349
leukocyte chemotaxisGO:0030595690.336
adenylate cyclase inhibiting g protein coupled receptor signaling pathwayGO:0007193200.331
response to molecule of bacterial originGO:00022371430.329
eosinophil mediated immunityGO:000244710.328
negative regulation of growthGO:0045926990.324
dna metabolic processGO:00062593030.322
production of molecular mediator of immune responseGO:00024401030.319
regulation of kinase activityGO:00435492490.313
cation transportGO:00068123990.313
regulation of innate immune responseGO:0045088910.310
cell activation involved in immune responseGO:00022631260.308
regulation of lymphocyte activationGO:00512492400.306
regulation of lymphocyte proliferationGO:00506701170.306
response to organonitrogen compoundGO:00102432460.304
second messenger mediated signalingGO:0019932730.300
regulation of leukocyte proliferationGO:00706631210.298
positive regulation of t cell costimulationGO:200052520.298
myeloid leukocyte activationGO:0002274830.296
blood vessel morphogenesisGO:00485142850.294
regulation of protein transportGO:00512231630.288
immune response regulating signaling pathwayGO:00027641250.287
g protein coupled receptor internalizationGO:000203130.284
carbohydrate derivative biosynthetic processGO:19011371830.284
erk1 and erk2 cascadeGO:0070371770.283
negative regulation of phosphorus metabolic processGO:00105631840.270
negative regulation of immune system processGO:00026832090.269
ossificationGO:00015032160.265
positive regulation of tumor necrosis factor biosynthetic processGO:004253580.261
positive regulation of chemotaxisGO:0050921380.257
axonogenesisGO:00074092740.256
regulation of leukocyte differentiationGO:19021051590.253
glial cell differentiationGO:00100011310.251
positive regulation of protein modification processGO:00314012990.250
positive regulation of neutrophil chemotaxisGO:0090023120.250
organic anion transportGO:00157111370.247
granulocyte chemotaxisGO:0071621390.243
regulation of leukocyte mediated immunityGO:00027031040.242
positive regulation of leukocyte differentiationGO:1902107860.241
response to lipopolysaccharideGO:00324961280.240
positive regulation of immunological synapse formationGO:200052210.239
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.236
cell killingGO:0001906670.233
leukocyte migrationGO:00509001240.230
regulation of mapk cascadeGO:00434082480.229
negative regulation of eosinophil degranulationGO:004331010.227
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.225
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formationGO:200052610.224
monocyte extravasationGO:003569620.221
myeloid leukocyte mediated immunityGO:0002444420.221
alpha beta t cell differentiationGO:0046632690.215
negative regulation of intracellular signal transductionGO:19025321670.214
cellular response to prostaglandin d stimulusGO:007179910.213
lymphocyte mediated immunityGO:00024491390.213
regulation of alpha beta t cell activationGO:0046634530.211
cd4 positive alpha beta t cell differentiationGO:0043367410.211
microglia differentiationGO:001400420.210
regulation of cd8 positive alpha beta t cell extravasationGO:200044930.210
apoptotic signaling pathwayGO:00971903060.209
positive regulation of growthGO:00459271040.208
positive regulation of immune effector processGO:00026991070.207
regulation of ossificationGO:00302781120.206
lymphocyte proliferationGO:00466511640.205
regulation of anatomical structure sizeGO:00900661780.202
Mouse
positive regulation of programmed cell deathGO:00430682180.200
positive regulation of alpha beta t cell activationGO:0046635390.200
positive regulation of cd8 positive alpha beta t cell extravasationGO:200045120.198
cell chemotaxisGO:0060326810.197
microglial cell activation involved in immune responseGO:000228210.196
regulation of phospholipase c activityGO:190027430.195
regulation of immune complex clearance by monocytes and macrophagesGO:009026420.195
signal transduction in absence of ligandGO:0038034550.195
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiationGO:200072120.195
positive regulation of hematopoietic stem cell migrationGO:200047310.194
regulation of hematopoietic stem cell migrationGO:200047110.191
positive regulation of protein serine threonine kinase activityGO:00719021060.191
organonitrogen compound biosynthetic processGO:19015661920.190
positive regulation of cell migrationGO:00303351090.186
regulation of interferon gamma productionGO:0032649570.185
t cell activationGO:00421102890.183
membrane lipid biosynthetic processGO:0046467320.183
myeloid leukocyte differentiationGO:00025731190.181
dendritic cell differentiationGO:0097028260.180
positive regulation of t cell activationGO:00508701010.178
blood circulationGO:00080151950.177
Mouse
wound healingGO:00420601570.176
Mouse
cell divisionGO:00513011200.176
regulated secretory pathwayGO:0045055320.173
eosinophil activation involved in immune responseGO:000227810.170
immune response activating cell surface receptor signaling pathwayGO:0002429720.169
myeloid cell differentiationGO:00300992330.169
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.167
regulation of synaptic growth at neuromuscular junctionGO:000858240.166
positive regulation of nervous system developmentGO:00519622210.162
cellular response to cytokine stimulusGO:00713451890.162
regulation of t cell costimulationGO:200052320.157
forebrain developmentGO:00309003020.157
t helper 1 type immune responseGO:0042088250.153
regulation of t cell extravasationGO:200040730.153
regulation of immunological synapse formationGO:200052020.152
regulation of protein secretionGO:0050708820.151
negative regulation of cellular component organizationGO:00511291940.150
transmembrane transportGO:00550854120.146
regulation of response to woundingGO:19030341890.146
myeloid cell activation involved in immune responseGO:0002275340.145
regulation of blood vessel sizeGO:0050880560.144
Mouse
regulation of cell motilityGO:20001452360.144
adult behaviorGO:00305341350.143
negative regulation of ras protein signal transductionGO:0046580180.143
negative regulation of phosphate metabolic processGO:00459361840.142
positive regulation of cytokine biosynthetic processGO:0042108400.142
negative regulation of cell proliferationGO:00082852960.139
action potentialGO:0001508780.137
Rat
memoryGO:0007613580.137
vasoconstrictionGO:0042310270.137
Mouse
somatic recombination of immunoglobulin gene segmentsGO:0016447420.136
cellular amino acid metabolic processGO:00065201030.134
positive regulation of lymphocyte differentiationGO:0045621610.134
interleukin 12 secretionGO:007261030.133
immune response regulating cell surface receptor signaling pathwayGO:0002768800.133
lymphocyte differentiationGO:00300982420.131
regulation of exocytosisGO:0017157610.130
interferon gamma productionGO:0032609670.129
eosinophil degranulationGO:004330810.128
fat cell differentiationGO:00454441600.128
lymphocyte activation involved in immune responseGO:0002285930.127
adenylate cyclase activating g protein coupled receptor signaling pathwayGO:0007189300.127
sequestering of metal ionGO:0051238190.127
regulation of secretionGO:00510462740.127
toll like receptor signaling pathwayGO:0002224380.126
regulation of tube sizeGO:0035150570.125
Mouse
membrane organizationGO:00610242450.125
homeostasis of number of cellsGO:00488722100.124
positive regulation of leukocyte mediated immunityGO:0002705700.124
purine containing compound metabolic processGO:00725213110.123
chemotaxisGO:00069352470.122
regulation of secretion by cellGO:19035302490.122
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.122
regulation of antigen receptor mediated signaling pathwayGO:0050854290.121
positive regulation of myeloid leukocyte differentiationGO:0002763260.121
carboxylic acid transportGO:00469421000.118
negative regulation of cell activationGO:00508661110.118
regulation of tumor necrosis factor biosynthetic processGO:0042534100.118
positive regulation of phospholipase c activityGO:001086320.118
ribonucleoside metabolic processGO:00091192450.117
immune complex clearance by monocytes and macrophagesGO:000243620.117
mapk cascadeGO:00001652810.116
response to acid chemicalGO:00011011110.114
phosphatidylinositol mediated signalingGO:0048015410.113
positive regulation of behaviorGO:0048520400.113
platelet activationGO:0030168400.113
Mouse
glycosyl compound metabolic processGO:19016572460.112
cellular response to growth factor stimulusGO:00713631970.112
angiogenesisGO:00015252010.112
positive regulation of dendritic cell chemotaxisGO:200051010.112
leukocyte proliferationGO:00706611720.111
circulatory system processGO:00030131970.111
Mouse
telencephalon cell migrationGO:0022029550.109
response to growth factorGO:00708481980.109
b cell activation involved in immune responseGO:0002312500.108
antigen receptor mediated signaling pathwayGO:0050851640.108
rhythmic processGO:00485111740.107
regulation of inflammatory response to antigenic stimulusGO:0002861210.107
regulation of inflammatory responseGO:00507271470.107
positive regulation of protein phosphorylationGO:00019342420.106
regulation of blood circulationGO:1903522930.106
Mouse
renal system developmentGO:00720012250.105
cytoplasmic transportGO:00164822340.104
divalent inorganic cation transportGO:00725111780.104
regulation of cytokine secretionGO:0050707610.104
positive regulation of neutrophil migrationGO:1902624120.102
neuron projection guidanceGO:00974851410.102
sphingolipid metabolic processGO:0006665450.101
negative regulation of protein metabolic processGO:00512482820.101
calcium ion transport into cytosolGO:0060402480.101
positive regulation of acute inflammatory responseGO:0002675160.100
regulation of cell migrationGO:00303342190.100
mature dendritic cell differentiationGO:009702930.100
purine ribonucleoside triphosphate catabolic processGO:00092071990.100
immune complex clearanceGO:000243420.099
regulation of dendritic cell chemotaxisGO:200050810.099
cell adhesionGO:00071553290.099
anion transportGO:00068201770.099
calcium ion transportGO:00068161590.099
cd4 positive alpha beta t cell activationGO:0035710450.098
antigen processing and presentationGO:0019882470.098
t cell proliferationGO:00420981200.098
regulation of osteoblast proliferationGO:0033688150.097
negative regulation of cytokine productionGO:0001818840.096
regulation of myeloid cell differentiationGO:0045637960.096
morphogenesis of a branching epitheliumGO:00611381930.095
multicellular organismal signalingGO:0035637910.095
Rat
regulation of protein kinase b signalingGO:0051896560.094
wnt signaling pathwayGO:00160551880.093
epithelial tube morphogenesisGO:00605623030.093
vascular process in circulatory systemGO:0003018620.092
Mouse
purine ribonucleotide metabolic processGO:00091502900.091
positive regulation of kinase activityGO:00336741550.091
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.091
organophosphate biosynthetic processGO:00904071220.091
nucleobase containing small molecule metabolic processGO:00550863520.090
positive regulation of t cell proliferationGO:0042102520.090
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.089
regulation of homeostatic processGO:00328441820.089
cation homeostasisGO:00550802120.089
myeloid leukocyte migrationGO:0097529570.088
ribose phosphate metabolic processGO:00196932910.088
forebrain cell migrationGO:0021885580.087
positive regulation of cell motilityGO:20001471160.087
tumor necrosis factor productionGO:0032640500.087
regulation of cytokine biosynthetic processGO:0042035590.087
regulation of chemotaxisGO:0050920530.086
regulation of intracellular transportGO:00323861590.086
regulation of membrane potentialGO:00423911920.085
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.085
regulation of toll like receptor 4 signaling pathwayGO:003414340.082
positive regulation of inflammatory responseGO:0050729470.082
reactive oxygen species biosynthetic processGO:190340980.082
tumor necrosis factor biosynthetic processGO:0042533100.082
tissue remodelingGO:00487711020.082
regulation of transferase activityGO:00513382630.081
granulocyte migrationGO:0097530430.080
regulation of leukocyte degranulationGO:0043300200.080
ear developmentGO:00435832000.080
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.079
regulation of neuron projection developmentGO:00109751690.079
purine nucleotide metabolic processGO:00061633020.078
glycosyl compound catabolic processGO:19016582060.078
metal ion homeostasisGO:00550651890.078
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.077
somatic diversification of immune receptorsGO:0002200530.076
regulation of ion transportGO:00432692150.075
inorganic cation transmembrane transportGO:00986622070.075
t cell activation involved in immune responseGO:0002286430.074
extracellular structure organizationGO:00430621480.074
regulation of systemic arterial blood pressureGO:0003073610.074
Mouse
regulation of apoptotic signaling pathwayGO:20012331970.073
response to hypoxiaGO:0001666580.073
Mouse
inflammatory response to antigenic stimulusGO:0002437300.073
leukocyte degranulationGO:0043299270.073
positive regulation of fat cell differentiationGO:0045600320.072
cellular homeostasisGO:00197252400.072
platelet derived growth factor receptor signaling pathwayGO:0048008320.072
cellular lipid metabolic processGO:00442553230.072
microglial cell activationGO:000177430.071
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.071
positive regulation of endothelial cell proliferationGO:0001938170.071
positive regulation of transferase activityGO:00513471670.071
multicellular organismal response to stressGO:0033555620.070
Mouse
t cell differentiation involved in immune responseGO:0002292300.070
hypersensitivityGO:0002524100.069
kidney developmentGO:00018222130.069
blastocyst developmentGO:0001824800.069
symbiosis encompassing mutualism through parasitismGO:0044403830.068
reactive oxygen species metabolic processGO:0072593840.068
purine ribonucleoside metabolic processGO:00461282410.068
nucleoside triphosphate catabolic processGO:00091432050.068
ribonucleotide biosynthetic processGO:0009260590.068
regulation of t helper 1 type immune responseGO:0002825170.067
cellular response to acid chemicalGO:0071229680.067
pattern recognition receptor signaling pathwayGO:0002221470.067
regulation of monocyte chemotaxisGO:009002530.067
positive regulation of lymphocyte mediated immunityGO:0002708620.067
alpha beta t cell activation involved in immune responseGO:0002287310.066
sensory perceptionGO:00076002450.066
carbohydrate derivative catabolic processGO:19011362310.066
phospholipase c activating g protein coupled receptor signaling pathwayGO:0007200260.066
interspecies interaction between organismsGO:0044419830.066
positive regulation of metanephric mesenchymal cell migrationGO:200059110.066
regulation of protein kinase activityGO:00458592320.066
camp biosynthetic processGO:0006171310.066
multicellular organism growthGO:00352641610.066
cytokine metabolic processGO:0042107710.066
ameboidal type cell migrationGO:00016671280.065
cation transmembrane transportGO:00986552660.065
regulation of neutrophil differentiationGO:004565820.065
osteoclast differentiationGO:0030316620.065
regulation of hypersensitivityGO:0002883100.065
nucleoside catabolic processGO:00091642060.064
negative regulation of response to woundingGO:1903035770.064
positive regulation of t helper 1 type immune responseGO:0002827120.064
regulation of muscle contractionGO:0006937490.064
Mouse
cell fate commitmentGO:00451652100.063
positive regulation of protein transportGO:0051222930.063
white fat cell proliferationGO:007034320.063
regulation of myeloid leukocyte mediated immunityGO:0002886250.063
muscle tissue developmentGO:00605373080.063
Mouse
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.063
mast cell activation involved in immune responseGO:0002279200.062
lipid biosynthetic processGO:00086101790.062
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.062
dna recombinationGO:0006310920.061
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.061
positive regulation of protein kinase activityGO:00458601440.060
neuron projection extensionGO:1990138640.059
protein kinase b signalingGO:0043491740.059
learning or memoryGO:00076111480.059
gland developmentGO:00487323300.059
positive regulation of interferon gamma productionGO:0032729390.059
neuronal action potentialGO:0019228540.059
Rat
modification of morphology or physiology of other organism involved in symbiotic interactionGO:0051817160.059
positive regulation of erk1 and erk2 cascadeGO:0070374470.058
smooth muscle contractionGO:0006939440.058
Mouse
regulation of tissue remodelingGO:0034103380.058
phagocytosisGO:0006909660.058
positive regulation of phospholipase activityGO:001051830.058
morphogenesis of a branching structureGO:00017632030.057
glycoprotein metabolic processGO:00091001160.057
positive regulation of intracellular transportGO:0032388700.057
neutrophil differentiationGO:003022330.057
regulation of vasoconstrictionGO:0019229140.057
Mouse
endothelial cell proliferationGO:0001935270.057
positive regulation of cell deathGO:00109422240.057
amino acid transportGO:0006865610.057
acute inflammatory responseGO:0002526410.057
urinary bladder smooth muscle contractionGO:001483250.056
Mouse
lysosome localizationGO:0032418200.056
cyclic purine nucleotide metabolic processGO:0052652430.056
stem cell developmentGO:00488642190.056
coagulationGO:0050817780.056
Mouse
positive regulation of alpha beta t cell differentiationGO:0046638280.056
regulation of cell sizeGO:0008361720.055
cellular response to molecule of bacterial originGO:0071219830.055
nucleoside phosphate metabolic processGO:00067533380.054
regulation of neuron differentiationGO:00456642810.054
positive regulation of immune complex clearance by monocytes and macrophagesGO:009026520.054
positive regulation of cell developmentGO:00107202370.054
regulation of vesicle mediated transportGO:00606271390.054
negative regulation of multi organism processGO:0043901680.054
regulation of canonical wnt signaling pathwayGO:0060828820.054
regulation of protein serine threonine kinase activityGO:00719001570.053
ion transmembrane transportGO:00342203610.053
regulation of interleukin 2 productionGO:0032663280.053
glycerophospholipid metabolic processGO:0006650710.053
positive regulation of hydrolase activityGO:00513451480.053
Mouse
response to prostaglandin dGO:007179810.052
cellular carbohydrate metabolic processGO:00442621190.052
positive regulation of response to woundingGO:1903036660.052
negative regulation of inflammatory responseGO:0050728610.052
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.052
nucleotide metabolic processGO:00091173320.051
epidermis developmentGO:00085441870.051
sphingosine 1 phosphate signaling pathwayGO:000337630.051
muscle system processGO:00030121410.051
Mouse
immunoglobulin mediated immune responseGO:0016064690.051
cellular metal ion homeostasisGO:00068751510.051
cognitionGO:00508901490.050
vascular endothelial growth factor productionGO:0010573130.050
regulation of cell adhesionGO:00301551540.050
negative regulation of lymphocyte proliferationGO:0050672450.050
germ cell developmentGO:00072811850.050
regulation of b cell activationGO:0050864810.050
calcium ion homeostasisGO:00550741270.049
negative regulation of regulated secretory pathwayGO:190330670.049
release of sequestered calcium ion into cytosolGO:0051209420.049
response to oxygen levelsGO:0070482620.049
Mouse
innate immune response activating signal transductionGO:0002758500.049
positive regulation of t cell differentiationGO:0045582520.049
canonical wnt signaling pathwayGO:00600701300.049
telencephalon developmentGO:00215371860.049
tumor necrosis factor superfamily cytokine productionGO:0071706510.048
positive regulation of protein secretionGO:0050714520.048
acid secretionGO:0046717330.048
cellular ketone metabolic processGO:0042180840.048
regulation of acute inflammatory responseGO:0002673270.048
positive regulation of heart rate by epinephrine norepinephrineGO:000199640.048
leukocyte apoptotic processGO:0071887710.048
neutrophil chemotaxisGO:0030593360.048
adaptive immune responseGO:00022501550.048
regulation of system processGO:00440572000.048
Mouse
neutrophil migrationGO:1990266370.047
regulation of lymphocyte differentiationGO:00456191070.047
ribonucleotide metabolic processGO:00092592910.047
regulation of t cell differentiationGO:0045580830.046
type 2 immune responseGO:0042092230.046
regulation of cellular response to growth factor stimulusGO:0090287820.046
monocarboxylic acid metabolic processGO:00327871910.046
oocyte differentiationGO:0009994350.046
regulation of cell morphogenesis involved in differentiationGO:00107691510.046
regulation of erk1 and erk2 cascadeGO:0070372710.046
hematopoietic stem cell migrationGO:003570110.045
positive regulation of glial cell differentiationGO:0045687210.045
peptidyl amino acid modificationGO:00181933360.045
serotonin receptor signaling pathwayGO:000721080.045
positive regulation of inflammatory response to antigenic stimulusGO:0002863110.045
oxidation reduction processGO:00551143420.045
t cell receptor signaling pathwayGO:0050852460.045
cytokine secretionGO:0050663720.045
alpha beta t cell differentiation involved in immune responseGO:0002293300.045
transforming growth factor beta receptor signaling pathwayGO:0007179710.045
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.045
mast cell degranulationGO:0043303190.045
peptidyl tyrosine modificationGO:00182121450.045
heterocycle catabolic processGO:00467002800.045
cell growthGO:00160491300.044
mast cell mediated immunityGO:0002448200.044
positive regulation of homeostatic processGO:0032846640.044
cardiac muscle tissue growth involved in heart morphogenesisGO:000324510.044
regulation of calcium mediated signalingGO:0050848190.044
regulation of cellular component biogenesisGO:00440871810.044
regulation of mast cell degranulationGO:0043304160.044
regulation of dna recombinationGO:0000018340.044
response to transforming growth factor betaGO:0071559880.043
rho protein signal transductionGO:0007266320.043
regulation of toll like receptor signaling pathwayGO:0034121200.043
cyclic nucleotide biosynthetic processGO:0009190440.043
skeletal system morphogenesisGO:00487052030.043
activation of adenylate cyclase activityGO:000719040.043
tissue homeostasisGO:00018941150.043
growth of symbiont in hostGO:0044117230.042
cellular response to lipopolysaccharideGO:0071222770.042
regulation of alpha beta t cell differentiationGO:0046637350.042
odontogenesis of dentin containing toothGO:0042475660.042
plasma membrane organizationGO:0007009900.042
dicarboxylic acid transportGO:0006835290.042
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.042
positive regulation of calcium mediated signalingGO:0050850150.042
branching involved in salivary gland morphogenesisGO:0060445260.042
aromatic compound catabolic processGO:00194392860.041
sodium ion transportGO:0006814730.041
Rat
tolerance inductionGO:0002507140.041
regulation of osteoclast differentiationGO:0045670360.041
mammary gland morphogenesisGO:0060443540.041
positive regulation of camp metabolic processGO:0030816190.041
interleukin 6 productionGO:0032635580.041
chemokine mediated signaling pathwayGO:0070098170.040
sequestering of calcium ionGO:0051208180.040
regulation of g protein coupled receptor protein signaling pathwayGO:0008277370.040
positive regulation of apoptotic signaling pathwayGO:2001235950.040
extracellular matrix organizationGO:00301981470.040
positive regulation of stem cell proliferationGO:2000648590.040
gastrin induced gastric acid secretionGO:000169810.040
negative regulation of innate immune responseGO:0045824170.039
generation of precursor metabolites and energyGO:00060911030.039
regulation of regulated secretory pathwayGO:1903305200.039
organic cyclic compound catabolic processGO:19013612950.039
anatomical structure homeostasisGO:00602491450.039
humoral immune responseGO:0006959570.039
regulation of osteoblast differentiationGO:0045667670.039
regulation of t cell activationGO:00508631700.039
exocrine system developmentGO:0035272450.039
negative regulation of exocytosisGO:0045920120.038
regulation of rho protein signal transductionGO:0035023710.038
vesicle localizationGO:0051648860.038
branching morphogenesis of an epithelial tubeGO:00487541590.038
regulation of cell cycleGO:00517262810.038

P2rx7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.060
disease of cellular proliferationDOID:1456600.060
organ system cancerDOID:005068600.060