Mus musculus

20 known processes

Col6a1

collagen, type VI, alpha 1

(Aliases: Col6a-1,AI747156)

Col6a1 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to amino acid stimulusGO:0071230290.991
extracellular structure organizationGO:00430621480.988
extracellular matrix organizationGO:00301981470.987
response to amino acidGO:0043200370.978
cellular response to growth factor stimulusGO:00713631970.813
cell substrate adhesionGO:00315891300.788
response to organonitrogen compoundGO:00102432460.715
protein trimerizationGO:0070206130.713
Human
regulation of cell adhesionGO:00301551540.707
regulation of cell substrate adhesionGO:0010810730.707
fibril organizationGO:009743520.701
ossificationGO:00015032160.683
Human
connective tissue developmentGO:00614481790.674
retinal blood vessel morphogenesisGO:006130430.667
response to growth factorGO:00708481980.646
skeletal system developmentGO:00015013560.643
cell matrix adhesionGO:0007160680.594
cellular response to acid chemicalGO:0071229680.582
palate developmentGO:0060021760.562
protein heterotrimerizationGO:007020880.555
Human
aorta smooth muscle tissue morphogenesisGO:006041420.516
cellular response to transforming growth factor beta stimulusGO:0071560880.500
limb bud formationGO:0060174100.495
regulation of removal of superoxide radicalsGO:200012140.490
skeletal system morphogenesisGO:00487052030.480
negative regulation of gastrulationGO:200054230.475
cellular response to organonitrogen compoundGO:00714171450.462
positive regulation of ras protein signal transductionGO:0046579130.455
extrinsic apoptotic signaling pathwayGO:00971911260.445
cell adhesionGO:00071553290.421
anatomical structure homeostasisGO:00602491450.400
bone developmentGO:00603481200.378
cartilage condensationGO:0001502180.376
chondrocyte differentiationGO:0002062720.353
extracellular fibril organizationGO:004320620.330
lung developmentGO:00303241640.319
respiratory tube developmentGO:00303231670.303
protein oligomerizationGO:0051259670.290
Human
regulation of apoptotic signaling pathwayGO:20012331970.273
aorta morphogenesisGO:0035909220.270
response to acid chemicalGO:00011011110.259
protein heterooligomerizationGO:0051291140.251
Human
signal transduction in absence of ligandGO:0038034550.239
sensory perception of soundGO:0007605970.232
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.228
regulation of cell motilityGO:20001452360.226
elastic fiber assemblyGO:004825140.225
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.224
negative regulation of cell adhesionGO:0007162450.223
head morphogenesisGO:0060323340.220
positive regulation of cell substrate adhesionGO:0010811470.216
embryonic organ morphogenesisGO:00485622760.215
negative regulation of cell substrate adhesionGO:0010812160.212
limb morphogenesisGO:00351081490.211
muscle tissue developmentGO:00605373080.206
wound healingGO:00420601570.204
cartilage development involved in endochondral bone morphogenesisGO:0060351240.202
bone trabecula formationGO:006034690.202
cardiac muscle tissue developmentGO:00487381300.200
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.196
forebrain developmentGO:00309003020.194
replacement ossificationGO:0036075260.191
response to superoxideGO:0000303160.185
embryonic skeletal system morphogenesisGO:0048704910.170
proteoglycan metabolic processGO:0006029380.169
cartilage developmentGO:00512161400.166
negative regulation of apoptotic signaling pathwayGO:20012341040.165
negative regulation of tooth mineralizationGO:007017110.157
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001239260.155
bone morphogenesisGO:0060349780.153
notochord developmentGO:0030903200.153
basement membrane organizationGO:007171180.150
aorta developmentGO:0035904230.149
sensory perceptionGO:00076002450.148
negative regulation of blood vessel morphogenesisGO:2000181250.147
embryonic skeletal system developmentGO:00487061200.145
trabecula formationGO:0060343240.144
protein hydroxylationGO:001812640.143
collagen fibril organizationGO:0030199320.136
cellular response to superoxideGO:0071451140.134
negative regulation of cell migrationGO:0030336590.132
face developmentGO:0060324380.131
negative regulation of neuron migrationGO:200122360.130
trabecula morphogenesisGO:0061383400.129
cardiac chamber morphogenesisGO:0003206930.129
response to transforming growth factor betaGO:0071559880.127
tissue homeostasisGO:00018941150.126
blood vessel morphogenesisGO:00485142850.124
skeletal muscle organ developmentGO:00605381630.120
heart morphogenesisGO:00030071780.119
cell aggregationGO:0098743180.118
regulation of ras protein signal transductionGO:00465781140.117
growth plate cartilage developmentGO:0003417140.116
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.114
direct ossificationGO:003607250.111
endochondral bone morphogenesisGO:0060350500.110
regulation of rho protein signal transductionGO:0035023710.110
cerebral cortex developmentGO:0021987860.108
regulation of cell migrationGO:00303342190.105
regulation of peptidase activityGO:0052547960.102
multicellular organismal homeostasisGO:00488711640.102
neuron migrationGO:00017641220.101
angiogenesisGO:00015252010.099
small gtpase mediated signal transductionGO:0007264970.096
muscle tissue morphogenesisGO:0060415530.093
regulation of tooth mineralizationGO:007017020.092
negative regulation of angiogenesisGO:0016525250.090
limb developmentGO:00601731660.090
response to organic cyclic compoundGO:00140701980.089
appendage morphogenesisGO:00351071490.088
sensory perception of mechanical stimulusGO:00509541070.088
response to catecholamineGO:007186940.084
respiratory system developmentGO:00605411900.084
positive regulation of cell adhesionGO:0045785800.083
nephron developmentGO:00720061090.081
digestive system developmentGO:00551232000.081
Human
negative regulation of ossificationGO:0030279490.081
artery developmentGO:0060840530.081
sensory organ morphogenesisGO:00905962420.079
cellular response to bmp stimulusGO:0071773140.078
regulation of proteolysisGO:00301621640.076
response to inorganic substanceGO:0010035960.075
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001240160.075
response to decreased oxygen levelsGO:0036293590.073
glycoprotein metabolic processGO:00091001160.072
cardiac ventricle morphogenesisGO:0003208500.072
removal of superoxide radicalsGO:0019430120.070
appendage developmentGO:00487361660.067
body morphogenesisGO:0010171450.067
positive regulation of peptidase activityGO:0010952490.066
regulation of angiogenesisGO:0045765810.066
collagen biosynthetic processGO:003296470.064
regulation of sphingolipid biosynthetic processGO:009015310.062
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.061
digestive tract developmentGO:00485651900.060
Human
face morphogenesisGO:0060325290.060
positive regulation of bone remodelingGO:0046852130.058
renal system developmentGO:00720012250.058
collagen metabolic processGO:0032963170.057
positive regulation of rho protein signal transductionGO:003502570.057
negative regulation of immune system processGO:00026832090.056
ventricular cardiac muscle tissue morphogenesisGO:0055010320.056
regulation of chondrocyte differentiationGO:0032330330.056
regulation of neuron projection developmentGO:00109751690.056
response to bmpGO:0071772140.055
reactive oxygen species metabolic processGO:0072593840.054
transforming growth factor beta receptor signaling pathwayGO:0007179710.053
single organism cell adhesionGO:00986021560.052
negative regulation of signal transduction in absence of ligandGO:1901099160.051
positive regulation of metanephric mesenchymal cell migrationGO:200059110.049
negative regulation of cell developmentGO:00107211690.048
positive regulation of hydrolase activityGO:00513451480.048
negative regulation of cell proliferationGO:00082852960.047
skin developmentGO:00435882200.046
ear developmentGO:00435832000.045
urogenital system developmentGO:00016552610.044
negative regulation of nervous system developmentGO:00519611560.044
cardiac muscle tissue morphogenesisGO:0055008440.044
tendon developmentGO:003598960.043
otic vesicle developmentGO:0071599140.043
tissue migrationGO:0090130680.043
gland developmentGO:00487323300.043
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512260.042
rho protein signal transductionGO:0007266320.042
multicellular organismal catabolic processGO:004424370.042
defense response to bacteriumGO:00427421190.042
retinal ganglion cell axon guidanceGO:0031290180.041
chondrocyte developmentGO:0002063240.041
spermatogenesisGO:00072832840.040
extracellular matrix assemblyGO:0085029120.040
negative regulation of cell motilityGO:2000146610.039
insulin metabolic processGO:190114230.039
ras protein signal transductionGO:0007265770.039
regulation of neuron migrationGO:2001222220.039
plasma membrane organizationGO:0007009900.038
positive regulation of cell developmentGO:00107202370.038
response to oxidative stressGO:00069791230.038
pallium developmentGO:00215431200.037
regulation of hydrolase activityGO:00513362460.036
regulation of endodermal cell differentiationGO:190322420.036
bone resorptionGO:0045453380.036
cellular response to oxygen radicalGO:0071450140.035
response to peptide hormoneGO:00434341270.035
response to peptideGO:19016521360.035
positive regulation of axon extensionGO:0045773200.035
antibacterial peptide secretionGO:000277910.034
cardiac ventricle developmentGO:0003231830.033
response to thyroid hormoneGO:009706620.033
negative regulation of epithelial cell proliferationGO:0050680640.032
peptide cross linking via chondroitin 4 sulfate glycosaminoglycanGO:001980080.032
regulation of ceramide biosynthetic processGO:200030310.031
positive regulation of cell migrationGO:00303351090.031
peptide cross linkingGO:0018149100.031
intussusceptive angiogenesisGO:000204120.030
response to monosaccharideGO:0034284670.030
cell type specific apoptotic processGO:00972852680.029
positive regulation of bone resorptionGO:0045780130.029
cellular lipid metabolic processGO:00442553230.029
sequestering of bmp in extracellular matrixGO:003558230.028
regulation of hormone levelsGO:00108172110.028
negative regulation of macrophage chemotaxisGO:001076010.028
striated muscle tissue developmentGO:00147062930.027
muscle cell developmentGO:00550011330.027
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.027
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.027
positive regulation of cell projection organizationGO:0031346950.027
anatomical structure maturationGO:0071695490.027
regulation of cell projection organizationGO:00313442060.027
synaptic transmission cholinergicGO:000727170.027
positive regulation of nervous system developmentGO:00519622210.026
antibacterial peptide productionGO:000277820.026
regulation of reactive oxygen species metabolic processGO:2000377400.026
cellular response to abiotic stimulusGO:0071214560.026
antimicrobial peptide secretionGO:000277610.025
cellular response to mechanical stimulusGO:007126070.025
regionalizationGO:00030023370.025
cellular response to thyroid hormone stimulusGO:009706710.025
positive regulation of phospholipase activityGO:001051830.025
erythropoietin mediated signaling pathwayGO:003816210.024
negative regulation of vasculature developmentGO:1901343260.024
multicellular organismal macromolecule metabolic processGO:0044259190.023
inner ear morphogenesisGO:00424721010.023
positive regulation of apoptotic processGO:00430652170.023
neuromuscular process controlling balanceGO:0050885590.023
regulation of vasculogenesisGO:200121290.022
superoxide metabolic processGO:0006801270.022
cardiac chamber developmentGO:00032051080.022
regulation of cartilage developmentGO:0061035440.022
synaptic transmissionGO:00072683290.022
regulation of extent of cell growthGO:0061387520.022
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.022
notochord cell differentiationGO:006003410.021
protein maturationGO:00516041760.021
negative regulation of growthGO:0045926990.021
sulfur compound metabolic processGO:00067901000.021
positive regulation of proteolysisGO:0045862850.021
cellular response to hormone stimulusGO:00328701500.021
cellular modified amino acid metabolic processGO:0006575630.021
oxidation reduction processGO:00551143420.021
membrane lipid metabolic processGO:0006643530.021
antimicrobial peptide biosynthetic processGO:000277720.020
endothelium developmentGO:0003158450.020
regulation of response to reactive oxygen speciesGO:190103190.020
regulation of system processGO:00440572000.020
telencephalon developmentGO:00215371860.020
negative regulation of biomineral tissue developmentGO:0070168110.019
axonogenesisGO:00074092740.019
protein processingGO:00164851630.019
endothelial cell apoptotic processGO:007257790.019
positive regulation of cellular amino acid metabolic processGO:004576430.019
integrin mediated signaling pathwayGO:0007229270.019
cellular response to fluid shear stressGO:007149840.019
regulation of neuron differentiationGO:00456642810.018
regulation of cellular response to stressGO:00801351590.018
biomineral tissue developmentGO:0031214640.018
developmental programmed cell deathGO:0010623410.018
hormone secretionGO:00468791280.018
regulation of bone resorptionGO:0045124240.017
vegf activated neuropilin signaling pathway involved in axon guidanceGO:190237810.017
eye photoreceptor cell developmentGO:0042462310.017
positive regulation of cell deathGO:00109422240.017
negative regulation of bmp signaling pathwayGO:0030514350.017
chondroitin sulfate metabolic processGO:0030204170.017
response to monoamineGO:007186740.017
peptidyl amino acid modificationGO:00181933360.017
regulation of organelle organizationGO:00330432890.017
innate immune responseGO:00450871570.017
regulation of macrophage migration inhibitory factor signaling pathwayGO:200044610.016
epithelial tube morphogenesisGO:00605623030.016
ventricular cardiac muscle tissue developmentGO:0003229380.016
retina development in camera type eyeGO:00600411190.016
positive regulation of programmed cell deathGO:00430682180.016
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathwayGO:003579310.016
regulation of cellular response to oxidative stressGO:1900407190.016
response to reactive oxygen speciesGO:0000302560.016
chondroitin sulfate proteoglycan metabolic processGO:0050654200.016
regulation of cellular amine metabolic processGO:0033238200.015
regulation of macrophage chemotaxisGO:001075880.015
ear morphogenesisGO:00424711180.015
myeloid leukocyte migrationGO:0097529570.015
metal ion homeostasisGO:00550651890.015
defense response to other organismGO:00985421970.015
regulation of synaptic vesicle primingGO:001080740.015
chemotaxisGO:00069352470.015
ameboidal type cell migrationGO:00016671280.015
synapse organizationGO:00508081250.015
cell adhesion mediated by integrinGO:0033627180.014
cellular response to external stimulusGO:0071496880.014
cellular response to nitric oxideGO:007173240.014
insulin processingGO:003007020.014
male gamete generationGO:00482322850.014
regulation of transmission of nerve impulseGO:005196910.014
cardiac muscle cell developmentGO:0055013390.014
regulation of secretion by cellGO:19035302490.014
oviduct developmentGO:006006630.014
bmp signaling pathwayGO:0030509930.014
cell recognitionGO:0008037830.013
regulation of endopeptidase activityGO:0052548890.013
regulation of cellular response to growth factor stimulusGO:0090287820.013
negative regulation of endodermal cell differentiationGO:190322510.013
peripheral nervous system axon regenerationGO:001401220.013
divalent metal ion transportGO:00708381720.013
apoptotic signaling pathwayGO:00971903060.013
positive regulation of growthGO:00459271040.012
organonitrogen compound biosynthetic processGO:19015661920.012
endothelial cell migrationGO:0043542440.012
odontogenesisGO:0042476780.012
lung alveolus developmentGO:0048286450.012
regulation of axon extensionGO:0030516430.012
regulation of gastrulationGO:0010470160.012
regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathwayGO:190023810.012
positive regulation of insulin secretionGO:0032024260.012
response to radiationGO:00093141650.012
sperm egg recognitionGO:0035036370.012
endochondral bone growthGO:0003416190.012
tissue remodelingGO:00487711020.012
gastrulationGO:00073691160.012
Human
cellular ketone metabolic processGO:0042180840.012
response to increased oxygen levelsGO:003629620.012
metanephric glomerular basement membrane developmentGO:007227410.012
regulation of secretionGO:00510462740.012
salivary gland developmentGO:0007431370.011
developmental growth involved in morphogenesisGO:00605601380.011
bone trabecula morphogenesisGO:0061430120.011
peptide hormone secretionGO:00300721090.011
developmental maturationGO:00217001930.011
cardiac cell developmentGO:0055006410.011
cellular response to oxidative stressGO:0034599760.011
notch signaling pathwayGO:0007219710.011
protein catabolic processGO:00301632210.011
response to steroid hormoneGO:0048545560.011
macrophage colony stimulating factor signaling pathwayGO:003814520.011
telencephalon cell migrationGO:0022029550.011
regulation of cell morphogenesis involved in differentiationGO:00107691510.011
positive regulation of neuron projection developmentGO:0010976790.011
cell cell adhesionGO:0098609410.011
cellular response to dna damage stimulusGO:00069742070.011
protein autoprocessingGO:001654020.011
regulation of multi organism processGO:00439001110.011
metanephric glomerular mesangial cell proliferation involved in metanephros developmentGO:007226230.011
medulla oblongata developmentGO:002155030.011
placenta blood vessel developmentGO:0060674310.011
wound healing spreading of cellsGO:004431980.011
renal system vasculature developmentGO:0061437150.011
negative regulation of cellular response to growth factor stimulusGO:0090288460.011
homeostasis of number of cellsGO:00488722100.011
antibacterial peptide biosynthetic processGO:000278020.011
meiotic cell cycle processGO:1903046770.011
neuron deathGO:00709971540.010
regulation of neuron deathGO:19012141340.010
hair follicle morphogenesisGO:0031069290.010
regulation of cell sizeGO:0008361720.010
negative regulation of neuron deathGO:1901215980.010
regulation of biomineral tissue developmentGO:0070167330.010
regulation of lipase activityGO:0060191150.010
sprouting angiogenesisGO:0002040260.010
macrophage migration inhibitory factor signaling pathwayGO:003569120.010
response to erythropoietinGO:003601710.010
endocytosisGO:00068971680.010
positive regulation of cell motilityGO:20001471160.010
digestive tract morphogenesisGO:00485461470.010
Human

Col6a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.976
Human
musculoskeletal system diseaseDOID:1700.976
Human
myopathyDOID:42300.976
Human
muscle tissue diseaseDOID:6600.976
Human
muscular diseaseDOID:008000000.976
Human
connective tissue diseaseDOID:6500.792
bone development diseaseDOID:008000600.792
osteochondrodysplasiaDOID:225600.792
bone diseaseDOID:008000100.792
muscular dystrophyDOID:988400.602
Human
ehlers danlos syndromeDOID:1335900.552
collagen diseaseDOID:85400.552
congenital muscular dystrophyDOID:005055700.426
Human
cardiovascular system diseaseDOID:128700.067
heart diseaseDOID:11400.067
osteogenesis imperfectaDOID:1234700.060
osteoporosisDOID:1147600.060
bone resorption diseaseDOID:008001100.060
bone remodeling diseaseDOID:008000500.060
eye and adnexa diseaseDOID:149200.015
retinal degenerationDOID:846600.015
eye diseaseDOID:561400.015
retinal diseaseDOID:567900.015
sensory system diseaseDOID:005015500.015
nervous system diseaseDOID:86300.015