Mus musculus

84 known processes

Nphp3

nephronophthisis 3 (adolescent)

(Aliases: pcy,MGC141550,C230078J01,3632410F03Rik,AI550417,D330020E01Rik)

Nphp3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
small gtpase mediated signal transductionGO:0007264970.375
sperm egg recognitionGO:0035036370.173
cell cell recognitionGO:0009988440.158
cellular lipid metabolic processGO:00442553230.127
single fertilizationGO:0007338820.115
positive regulation of lipid kinase activityGO:0090218110.111
regulation of systemic arterial blood pressure mediated by a chemical signalGO:0003044330.095
protein processingGO:00164851630.091
brain renin angiotensin systemGO:000203550.089
negative regulation of cellular component organizationGO:00511291940.088
purine nucleotide metabolic processGO:00061633020.086
wnt signaling pathwayGO:00160551880.070
Human
protein catabolic processGO:00301632210.066
binding of sperm to zona pellucidaGO:0007339340.066
regulation of transferase activityGO:00513382630.066
protein maturationGO:00516041760.065
positive regulation of lipid metabolic processGO:0045834400.065
regulation of kinase activityGO:00435492490.063
neurological system process involved in regulation of systemic arterial blood pressureGO:0001976180.062
regulation of phosphatidylinositol 3 kinase activityGO:0043551140.057
blood circulationGO:00080151950.055
ras protein signal transductionGO:0007265770.054
regulation of lipid kinase activityGO:0043550140.052
fertilizationGO:00095661270.052
protein modification by small protein conjugation or removalGO:00706472070.052
cell recognitionGO:0008037830.051
macromolecule catabolic processGO:00090572810.049
regulation of systemic arterial blood pressureGO:0003073610.047
aromatic compound catabolic processGO:00194392860.047
membrane organizationGO:00610242450.047
regulation of systemic arterial blood pressure by hormoneGO:0001990250.046
ribonucleotide metabolic processGO:00092592910.046
cellular amino acid metabolic processGO:00065201030.046
heterocycle catabolic processGO:00467002800.042
organonitrogen compound catabolic processGO:19015652640.041
protein ubiquitinationGO:00165671710.040
nucleoside triphosphate metabolic processGO:00091412300.040
cellular protein catabolic processGO:00442571550.039
cellular amine metabolic processGO:0044106440.038
positive regulation of phosphatidylinositol 3 kinase activityGO:0043552110.038
positive regulation of kinase activityGO:00336741550.037
protein modification by small protein conjugationGO:00324461870.037
positive regulation of hydrolase activityGO:00513451480.037
regulation of cellular ketone metabolic processGO:0010565660.037
nucleotide metabolic processGO:00091173320.036
nucleoside metabolic processGO:00091162460.036
ribonucleoside triphosphate metabolic processGO:00091992200.035
cellular macromolecule catabolic processGO:00442652060.035
cilium morphogenesisGO:00602711020.034
zymogen activationGO:0031638410.034
protein targetingGO:00066051430.034
kidney developmentGO:00018222130.034
regulation of blood pressureGO:0008217930.033
cation transmembrane transportGO:00986552660.033
amine metabolic processGO:0009308450.033
regulation of body fluid levelsGO:00508781620.033
apoptotic signaling pathwayGO:00971903060.032
phospholipid metabolic processGO:0006644870.032
purine ribonucleotide catabolic processGO:00091542080.032
urogenital system developmentGO:00016552610.032
embryonic organ morphogenesisGO:00485622760.032
Human
nucleoside phosphate catabolic processGO:19012922220.032
regulation of cell morphogenesis involved in differentiationGO:00107691510.031
organophosphate catabolic processGO:00464342320.031
purine nucleotide catabolic processGO:00061952110.031
purine ribonucleoside catabolic processGO:00461302050.031
protein localization to organelleGO:00333651850.030
oxidation reduction processGO:00551143420.030
negative regulation of cellular protein metabolic processGO:00322692470.029
organelle localizationGO:00516401790.029
organic cyclic compound catabolic processGO:19013612950.029
intracellular protein transportGO:00068862040.029
regulation of cellular catabolic processGO:00313292420.028
regulation of cellular amino acid metabolic processGO:000652150.028
purine ribonucleoside triphosphate metabolic processGO:00092052200.028
negative regulation of defense responseGO:0031348770.028
carbohydrate derivative catabolic processGO:19011362310.027
regulation of cellular amine metabolic processGO:0033238200.027
regulation of lipid metabolic processGO:00192161180.026
purine ribonucleotide metabolic processGO:00091502900.026
regulation of intracellular transportGO:00323861590.026
cellular homeostasisGO:00197252400.026
purine nucleoside metabolic processGO:00422782410.026
regulation of neuron differentiationGO:00456642810.025
protein localization to nucleusGO:00345041210.025
nucleoside catabolic processGO:00091642060.025
cytoplasmic transportGO:00164822340.025
regulation of neurotransmitter levelsGO:0001505870.025
locomotory behaviorGO:00076261950.025
proteolysis involved in cellular protein catabolic processGO:00516031470.025
ion transmembrane transportGO:00342203610.024
nucleobase containing small molecule metabolic processGO:00550863520.024
regulation of blood volume by renin angiotensinGO:000201670.024
glucose homeostasisGO:00425931280.023
cell adhesionGO:00071553290.023
ribonucleoside triphosphate catabolic processGO:00092031990.023
axonogenesisGO:00074092740.022
purine nucleoside triphosphate metabolic processGO:00091442260.022
carbohydrate homeostasisGO:00335001280.022
negative regulation of protein metabolic processGO:00512482820.022
purine containing compound catabolic processGO:00725232130.022
purine nucleoside triphosphate catabolic processGO:00091462030.021
positive regulation of purine nucleotide metabolic processGO:19005441140.021
extrinsic apoptotic signaling pathwayGO:00971911260.021
cellular ketone metabolic processGO:0042180840.021
endothelial cell migrationGO:0043542440.021
nucleoside phosphate metabolic processGO:00067533380.021
regulation of cell projection organizationGO:00313442060.021
nucleocytoplasmic transportGO:00069131390.020
cellular nitrogen compound catabolic processGO:00442702800.020
inorganic cation transmembrane transportGO:00986622070.020
negative regulation of protein modification processGO:00314001630.020
negative regulation of cellular amino acid metabolic processGO:004576300.020
glycosyl compound metabolic processGO:19016572460.020
negative regulation of inflammatory responseGO:0050728610.020
carbohydrate derivative biosynthetic processGO:19011371830.020
purine ribonucleoside triphosphate catabolic processGO:00092071990.020
glycoprotein biosynthetic processGO:0009101890.020
ribonucleotide catabolic processGO:00092612080.020
epithelial cell developmentGO:00020641590.020
cytokine mediated signaling pathwayGO:00192211150.020
regulation of organelle organizationGO:00330432890.020
regulation of purine nucleotide metabolic processGO:19005421690.019
regulation of inflammatory responseGO:00507271470.019
regulation of hydrolase activityGO:00513362460.019
purine ribonucleoside metabolic processGO:00461282410.019
fat cell differentiationGO:00454441600.019
negative regulation of cell proliferationGO:00082852960.019
regulation of hippo signalingGO:003533010.019
endocrine processGO:0050886390.019
epithelial cell migrationGO:0010631630.019
maintenance of locationGO:0051235890.019
atp metabolic processGO:0046034750.018
posttranscriptional regulation of gene expressionGO:00106081550.018
hematopoietic progenitor cell differentiationGO:00022441430.018
nucleoside triphosphate catabolic processGO:00091432050.018
inflammatory responseGO:00069542440.018
rac protein signal transductionGO:0016601130.018
ribonucleoside catabolic processGO:00424542060.018
organic anion transportGO:00157111370.018
canonical wnt signaling pathwayGO:00600701300.018
Human
glycoprotein metabolic processGO:00091001160.018
neuronal action potentialGO:0019228540.018
muscle contractionGO:00069361010.017
purine containing compound metabolic processGO:00725213110.017
regulation of nucleoside metabolic processGO:00091181300.017
amide transportGO:00428861380.017
positive regulation of cell developmentGO:00107202370.017
negative regulation of cellular amine metabolic processGO:003323910.017
purine ribonucleoside monophosphate metabolic processGO:0009167800.017
protein import into nucleusGO:0006606950.017
positive regulation of proteolysisGO:0045862850.017
positive regulation of cellular catabolic processGO:00313311480.017
anatomical structure homeostasisGO:00602491450.016
Human
transmembrane transportGO:00550854120.016
nucleotide catabolic processGO:00091662170.016
single organism cell adhesionGO:00986021560.016
regulation of cell cycleGO:00517262810.016
protein localization to membraneGO:00726571080.016
forebrain developmentGO:00309003020.016
establishment of organelle localizationGO:00516561220.016
inorganic ion transmembrane transportGO:00986602340.016
nucleoside monophosphate metabolic processGO:0009123850.016
negative regulation of phosphorylationGO:00423261660.016
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.016
regulation of systemic arterial blood pressure by renin angiotensinGO:0003081200.015
regulation of system processGO:00440572000.015
modification dependent macromolecule catabolic processGO:00436321330.015
lung developmentGO:00303241640.015
Human
carbohydrate metabolic processGO:00059752300.015
carboxylic acid catabolic processGO:0046395510.015
circulatory system processGO:00030131970.015
ribonucleoside metabolic processGO:00091192450.015
positive regulation of nervous system developmentGO:00519622210.015
protein importGO:00170381010.015
positive regulation of cellular amine metabolic processGO:003324050.015
transmission of nerve impulseGO:0019226760.015
renal system developmentGO:00720012250.015
respiratory system developmentGO:00605411900.015
Human
myeloid leukocyte differentiationGO:00025731190.015
regulation of cellular component sizeGO:00325351210.014
rho protein signal transductionGO:0007266320.014
rna interferenceGO:001624620.014
response to extracellular stimulusGO:00099911270.014
peptidyl amino acid modificationGO:00181933360.014
purine nucleoside monophosphate catabolic processGO:0009128580.014
establishment of protein localization to organelleGO:00725941180.014
establishment of protein localization to membraneGO:0090150540.014
cation transportGO:00068123990.014
endocytosisGO:00068971680.014
nitrogen compound transportGO:00717052710.014
regulation of cell sizeGO:0008361720.014
ribose phosphate metabolic processGO:00196932910.014
male gamete generationGO:00482322850.014
cellular component assembly involved in morphogenesisGO:00109271390.014
purine nucleoside catabolic processGO:00061522050.014
organelle disassemblyGO:190300820.014
regulation of anatomical structure sizeGO:00900661780.014
regulation of neuron projection developmentGO:00109751690.014
establishment of blood nerve barrierGO:000806530.014
reactive oxygen species metabolic processGO:0072593840.014
glycosyl compound catabolic processGO:19016582060.014
negative regulation of response to woundingGO:1903035770.014
negative regulation of phosphorus metabolic processGO:00105631840.014
regulation of epithelial cell proliferationGO:00506781410.014
ribonucleoside monophosphate metabolic processGO:0009161800.014
purine nucleoside monophosphate metabolic processGO:0009126810.014
negative regulation of canonical wnt signaling pathwayGO:0090090510.014
Human
regulation of response to woundingGO:19030341890.013
endomembrane system organizationGO:00102561470.013
negative regulation of wnt signaling pathwayGO:0030178730.013
Human
regulation of secretionGO:00510462740.013
kidney morphogenesisGO:0060993830.013
cellular ion homeostasisGO:00068731650.013
anion transportGO:00068201770.013
regulation of hormone levelsGO:00108172110.013
cellular divalent inorganic cation homeostasisGO:00725031270.013
homeostasis of number of cellsGO:00488722100.013
positive regulation of transferase activityGO:00513471670.013
nucleotide biosynthetic processGO:0009165780.013
macromolecular complex disassemblyGO:0032984430.013
spermatid differentiationGO:00485151150.013
organic acid transportGO:00158491010.013
response to peptideGO:19016521360.013
regulation of wnt signaling pathwayGO:00301111230.012
Human
multicellular organism growthGO:00352641610.012
negative regulation of phosphate metabolic processGO:00459361840.012
negative regulation of intracellular signal transductionGO:19025321670.012
positive regulation of cell growthGO:0030307330.012
regulation of feeding behaviorGO:006025930.012
myosin filament assemblyGO:003103420.012
regulation of purine nucleotide catabolic processGO:00331211220.012
ribose phosphate biosynthetic processGO:0046390590.012
photoreceptor cell outer segment organizationGO:003584550.012
positive regulation of nucleoside metabolic processGO:0045979910.012
cilium assemblyGO:0042384810.012
heart morphogenesisGO:00030071780.012
Human
microtubule based processGO:00070172360.012
retina development in camera type eyeGO:00600411190.012
somatic stem cell maintenanceGO:0035019470.012
sequestering of metal ionGO:0051238190.012
positive regulation of nucleotide metabolic processGO:00459811140.012
mitochondrion organizationGO:00070051340.012
regulation of proteolysisGO:00301621640.012
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.012
regulation of fat cell differentiationGO:0045598810.012
rna processingGO:00063961050.012
striated muscle tissue developmentGO:00147062930.012
respiratory tube developmentGO:00303231670.012
Human
epithelial tube morphogenesisGO:00605623030.012
Human
regulation of defense responseGO:00313472330.012
ameboidal type cell migrationGO:00016671280.012
cellular protein complex assemblyGO:00436231160.012
rhythmic processGO:00485111740.012
germ cell developmentGO:00072811850.011
regulation of extent of cell growthGO:0061387520.011
organelle assemblyGO:00709251770.011
organonitrogen compound biosynthetic processGO:19015661920.011
regulation of protein targetingGO:1903533610.011
response to acid chemicalGO:00011011110.011
small molecule biosynthetic processGO:00442831320.011
regulation of cellular component biogenesisGO:00440871810.011
positive regulation of purine nucleotide catabolic processGO:0033123880.011
extracellular structure organizationGO:00430621480.011
circadian regulation of gene expressionGO:0032922480.011
cell growthGO:00160491300.011
negative regulation of organelle organizationGO:0010639900.011
regulation of cytoskeleton organizationGO:00514931220.011
regulation of protein kinase activityGO:00458592320.011
ubiquitin dependent protein catabolic processGO:00065111290.011
regulation of synaptic growth at neuromuscular junctionGO:000858240.011
mapk cascadeGO:00001652810.011
ossificationGO:00015032160.011
nucleoside monophosphate catabolic processGO:0009125590.011
ribonucleoside monophosphate catabolic processGO:0009158570.011
intracellular mrna localizationGO:000829840.011
leukocyte homeostasisGO:0001776790.011
mrna metabolic processGO:0016071840.011
striated muscle myosin thick filament assemblyGO:007168810.011
developmental cell growthGO:0048588840.011
cell divisionGO:00513011200.011
reactive nitrogen species metabolic processGO:200105700.011
negative regulation of intracellular transportGO:0032387380.011
single organism nuclear importGO:1902593950.011
sequestering of calcium ionGO:0051208180.011
regulation of establishment of protein localizationGO:00702011810.010
generation of precursor metabolites and energyGO:00060911030.010
action potentialGO:0001508780.010
response to organonitrogen compoundGO:00102432460.010
cation homeostasisGO:00550802120.010
calcium ion transportGO:00068161590.010
muscle cell differentiationGO:00426922610.010
defecationGO:003042110.010
proteoglycan biosynthetic processGO:0030166200.010
nuclear transportGO:00511691390.010
mitochondrion distributionGO:004831140.010
sensory perceptionGO:00076002450.010
response to organic cyclic compoundGO:00140701980.010
regulation of metal ion transportGO:00109591060.010
protein depolymerizationGO:0051261340.010
cardiocyte differentiationGO:0035051870.010
hormone secretionGO:00468791280.010
regulation of protein catabolic processGO:00421761080.010
neurotransmitter transportGO:0006836760.010
regulation of nucleotide catabolic processGO:00308111220.010
regulation of keratinocyte proliferationGO:0010837150.010
morphogenesis of embryonic epitheliumGO:00163311590.010

Nphp3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nephronophthisisDOID:1271200.048
Human
disease of metabolismDOID:001466700.027
inherited metabolic disorderDOID:65500.021
cancerDOID:16200.019
disease of cellular proliferationDOID:1456600.019
organ system cancerDOID:005068600.019
disease of anatomical entityDOID:700.013
nervous system diseaseDOID:86300.013
immune system diseaseDOID:291400.011