IMP: Integrative Multi-species Prediction

Mus musculus

147 known processes

Etv4

ets variant gene 4 (E1A enhancer binding protein, E1AF)

(Aliases: AW414408,Pea-3,Pea3)

Entrez: 18612
Ensembl: ENSMUSG00000017724
UniProtKB: P28322
UniProtKB: A2A5C2
UniProtKB: A2A5C3

Process Predictions
Disease Predictions

Etv4 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
stem cell development	GO:0048864	219	0.940
regionalization	GO:0003002	337	0.926	Mouse
placenta development	GO:0001890	140	0.916	Mouse
heart morphogenesis	GO:0003007	178	0.900
stem cell differentiation	GO:0048863	268	0.853
gland development	GO:0048732	330	0.846
digestive tract development	GO:0048565	190	0.769	Mouse
cell fate commitment	GO:0045165	210	0.748	Mouse
cellular amine metabolic process	GO:0044106	44	0.712
stem cell maintenance	GO:0019827	130	0.638
epithelial cell proliferation	GO:0050673	174	0.618
gastrulation	GO:0007369	116	0.591	Mouse
skin development	GO:0043588	220	0.589
morphogenesis of a branching structure	GO:0001763	203	0.587
bmp signaling pathway	GO:0030509	93	0.545	Mouse
axon guidance	GO:0007411	141	0.543
striated muscle tissue development	GO:0014706	293	0.540
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.537	Mouse
regulation of transcription involved in cell fate commitment	GO:0060850	15	0.536	Mouse
cardiac chamber morphogenesis	GO:0003206	93	0.532
positive regulation of keratinocyte proliferation	GO:0010838	4	0.500
cardiac septum development	GO:0003279	59	0.486
regulation of cellular amino acid metabolic process	GO:0006521	5	0.467
epithelial tube morphogenesis	GO:0060562	303	0.466
digestive system development	GO:0055123	200	0.460	Mouse
regulation of cellular amine metabolic process	GO:0033238	20	0.457
epidermis morphogenesis	GO:0048730	33	0.451
neuron projection guidance	GO:0097485	141	0.445
developmental maturation	GO:0021700	193	0.445	Mouse
embryonic organ morphogenesis	GO:0048562	276	0.404
cardiac muscle tissue development	GO:0048738	130	0.401
regulation of epithelial cell proliferation	GO:0050678	141	0.398
formation of primary germ layer	GO:0001704	77	0.398	Mouse
axonogenesis	GO:0007409	274	0.389
pallium development	GO:0021543	120	0.374
skeletal system morphogenesis	GO:0048705	203	0.372
negative regulation of cell proliferation	GO:0008285	296	0.369
blood vessel morphogenesis	GO:0048514	285	0.354	Mouse
mesenchyme development	GO:0060485	152	0.347
camera type eye development	GO:0043010	266	0.343
cell adhesion	GO:0007155	329	0.343
chemotaxis	GO:0006935	247	0.339
small gtpase mediated signal transduction	GO:0007264	97	0.338
gliogenesis	GO:0042063	141	0.338
hair follicle morphogenesis	GO:0031069	29	0.334
regulation of epidermal cell differentiation	GO:0045604	21	0.329
mesenchymal cell development	GO:0014031	93	0.321
hindbrain development	GO:0030902	128	0.320
sensory organ morphogenesis	GO:0090596	242	0.315
wnt signaling pathway	GO:0016055	188	0.313	Mouse
ear development	GO:0043583	200	0.310
mesoderm morphogenesis	GO:0048332	64	0.307	Mouse
mesoderm formation	GO:0001707	62	0.307	Mouse
cardiac chamber development	GO:0003205	108	0.304
cell differentiation involved in embryonic placenta development	GO:0060706	26	0.303
cell maturation	GO:0048469	127	0.297	Mouse
regulation of cellular ketone metabolic process	GO:0010565	66	0.295
mesenchymal cell differentiation	GO:0048762	107	0.292
mesoderm development	GO:0007498	100	0.291	Mouse
columnar cuboidal epithelial cell differentiation	GO:0002065	82	0.291
embryonic appendage morphogenesis	GO:0035113	126	0.287
amine metabolic process	GO:0009308	45	0.287
embryonic heart tube morphogenesis	GO:0003143	51	0.286
mammary gland morphogenesis	GO:0060443	54	0.286
positive regulation of nervous system development	GO:0051962	221	0.282
synaptic transmission	GO:0007268	329	0.282	Mouse
digestive tract morphogenesis	GO:0048546	147	0.279	Mouse
auditory receptor cell fate determination	GO:0042668	3	0.279
embryonic placenta development	GO:0001892	98	0.278
regulation of organ morphogenesis	GO:2000027	144	0.278
hair cycle	GO:0042633	90	0.277
muscle cell differentiation	GO:0042692	261	0.273
neural crest cell development	GO:0014032	48	0.269
peptidyl amino acid modification	GO:0018193	336	0.265
hair follicle development	GO:0001942	85	0.260
diencephalon development	GO:0021536	63	0.259
mesodermal cell fate commitment	GO:0001710	17	0.253	Mouse
epidermis development	GO:0008544	187	0.251
organonitrogen compound biosynthetic process	GO:1901566	192	0.250
primary neural tube formation	GO:0014020	95	0.246
negative regulation of cellular amine metabolic process	GO:0033239	1	0.244
angiogenesis	GO:0001525	201	0.242
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.241
skin morphogenesis	GO:0043589	38	0.238
positive regulation of cellular amine metabolic process	GO:0033240	5	0.232
molting cycle	GO:0042303	90	0.231
mapk cascade	GO:0000165	281	0.230
epithelial cell development	GO:0002064	159	0.230
notch signaling pathway	GO:0007219	71	0.229	Mouse
segmentation	GO:0035282	93	0.222
glial cell development	GO:0021782	54	0.219
endodermal cell fate specification	GO:0001714	4	0.219
neural crest cell differentiation	GO:0014033	54	0.217
cardiac neural crest cell migration involved in outflow tract morphogenesis	GO:0003253	3	0.215
mammary gland epithelial cell proliferation	GO:0033598	24	0.215
muscle tissue development	GO:0060537	308	0.213
morphogenesis of a branching epithelium	GO:0061138	193	0.211
carbohydrate derivative biosynthetic process	GO:1901137	183	0.210
t cell differentiation	GO:0030217	174	0.210
positive regulation of cell development	GO:0010720	237	0.207
endothelial cell differentiation	GO:0045446	41	0.202	Mouse
positive regulation of protein phosphorylation	GO:0001934	242	0.202
regulation of cell cycle	GO:0051726	281	0.201
trophectodermal cell differentiation	GO:0001829	21	0.199
branching involved in mammary gland duct morphogenesis	GO:0060444	27	0.195
tube formation	GO:0035148	140	0.195
neural tube development	GO:0021915	160	0.194
negative regulation of epidermis development	GO:0045683	9	0.194
neuron migration	GO:0001764	122	0.188
appendage morphogenesis	GO:0035107	149	0.188	Zebrafish
neuronal action potential	GO:0019228	54	0.181
appendage development	GO:0048736	166	0.180	Zebrafish
negative regulation of neuron differentiation	GO:0045665	101	0.178
odontogenesis	GO:0042476	78	0.177
t cell activation	GO:0042110	289	0.175
positive regulation of kinase activity	GO:0033674	155	0.175
ras protein signal transduction	GO:0007265	77	0.174
forebrain development	GO:0030900	302	0.173
mammary gland duct morphogenesis	GO:0060603	38	0.172
cellular response to growth factor stimulus	GO:0071363	197	0.170
positive regulation of epithelial cell proliferation	GO:0050679	68	0.170
embryonic heart tube development	GO:0035050	65	0.169
regulation of neuron differentiation	GO:0045664	281	0.168
ventricular septum development	GO:0003281	42	0.167
regulation of epidermis development	GO:0045682	33	0.167
female sex differentiation	GO:0046660	84	0.166
mammary gland epithelium development	GO:0061180	65	0.165
cardiocyte differentiation	GO:0035051	87	0.164
cell fate specification	GO:0001708	72	0.164	Mouse
transmembrane transport	GO:0055085	412	0.162
cellular ketone metabolic process	GO:0042180	84	0.162
astrocyte fate commitment	GO:0060018	4	0.161
regulation of transcription involved in primary germ layer cell fate commitment	GO:0060796	2	0.161	Mouse
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation	GO:2000802	1	0.160
endocardial cushion to mesenchymal transition involved in heart valve formation	GO:0003199	4	0.159
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.159
urogenital system development	GO:0001655	261	0.158	Zebrafish
embryonic heart tube formation	GO:0003144	1	0.157
positive regulation of auditory receptor cell differentiation	GO:0045609	1	0.156
negative regulation of phosphorus metabolic process	GO:0010563	184	0.156
semaphorin plexin signaling pathway involved in outflow tract morphogenesis	GO:0071527	1	0.153
cellular amino acid metabolic process	GO:0006520	103	0.153
meiotic nuclear division	GO:0007126	115	0.152
lymphocyte differentiation	GO:0030098	242	0.152
fat cell differentiation	GO:0045444	160	0.151
erythrocyte differentiation	GO:0030218	88	0.149	Mouse
skeletal muscle cell differentiation	GO:0035914	66	0.149
midgut development	GO:0007494	4	0.148
hematopoietic progenitor cell differentiation	GO:0002244	143	0.147
cell division	GO:0051301	120	0.147
auditory receptor cell fate specification	GO:0042667	1	0.147
limb morphogenesis	GO:0035108	149	0.146	Zebrafish
regulation of cell division	GO:0051302	76	0.146
skeletal system development	GO:0001501	356	0.146
forebrain generation of neurons	GO:0021872	63	0.143
regulation of protein transport	GO:0051223	163	0.143
epithelial tube formation	GO:0072175	130	0.140
positive regulation of mechanoreceptor differentiation	GO:0045633	1	0.137
forebrain cell migration	GO:0021885	58	0.136
transmission of nerve impulse	GO:0019226	76	0.136
circulatory system process	GO:0003013	197	0.135
response to growth factor	GO:0070848	198	0.135
regulation of synaptic plasticity	GO:0048167	87	0.134
negative regulation of nervous system development	GO:0051961	156	0.134
regulation of embryonic development	GO:0045995	71	0.134
cervix development	GO:0060067	2	0.134
odontogenesis of dentin containing tooth	GO:0042475	66	0.134
negative regulation of cell development	GO:0010721	169	0.133
positive regulation of inner ear receptor cell differentiation	GO:2000982	1	0.132
blastocyst development	GO:0001824	80	0.132	Mouse
mesodermal cell differentiation	GO:0048333	22	0.132	Mouse
cardiac right ventricle formation	GO:0003219	3	0.131
branching morphogenesis of an epithelial tube	GO:0048754	159	0.129
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.128
regulation of mesoderm development	GO:2000380	12	0.128	Mouse
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process	GO:2000763	1	0.127
organelle fission	GO:0048285	170	0.125
skeletal muscle organ development	GO:0060538	163	0.122
mitral valve morphogenesis	GO:0003183	4	0.121
autonomic nervous system development	GO:0048483	43	0.120
neural crest cell migration	GO:0001755	32	0.120
ensheathment of neurons	GO:0007272	76	0.120
regulation of neuron projection development	GO:0010975	169	0.118
limbic system development	GO:0021761	72	0.118
regulation of mammary gland epithelial cell proliferation	GO:0033599	12	0.117
cytoplasmic transport	GO:0016482	234	0.116
embryonic epithelial tube formation	GO:0001838	130	0.115
canonical wnt signaling pathway	GO:0060070	130	0.115
glial cell differentiation	GO:0010001	131	0.114
ribose phosphate metabolic process	GO:0019693	291	0.113
locomotory behavior	GO:0007626	195	0.113	Mouse
kidney development	GO:0001822	213	0.113	Zebrafish
sensory perception	GO:0007600	245	0.112
renal vesicle induction	GO:0072034	3	0.112
response to transforming growth factor beta	GO:0071559	88	0.111
purine nucleotide metabolic process	GO:0006163	302	0.109
development of primary sexual characteristics	GO:0045137	143	0.108
embryonic digit morphogenesis	GO:0042733	56	0.108
muscle tissue morphogenesis	GO:0060415	53	0.108
blastocyst formation	GO:0001825	33	0.108
protein kinase c activating g protein coupled receptor signaling pathway	GO:0007205	4	0.107
embryonic genitalia morphogenesis	GO:0030538	4	0.107
regulation of transferase activity	GO:0051338	263	0.106
neural tube patterning	GO:0021532	43	0.106
chromatin modification	GO:0016568	187	0.105
chromatin organization	GO:0006325	206	0.104
ear morphogenesis	GO:0042471	118	0.104
central nervous system neuron differentiation	GO:0021953	162	0.103
hindbrain morphogenesis	GO:0021575	46	0.103
cardiac ventricle development	GO:0003231	83	0.103
myeloid cell homeostasis	GO:0002262	114	0.103	Mouse
outflow tract morphogenesis	GO:0003151	53	0.102
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.102
regulation of gtp catabolic process	GO:0033124	113	0.101
telencephalon cell migration	GO:0022029	55	0.101
establishment of planar polarity of embryonic epithelium	GO:0042249	16	0.101
ventricular septum morphogenesis	GO:0060412	27	0.101
forebrain neuron differentiation	GO:0021879	52	0.100
neural tube formation	GO:0001841	108	0.099
epithelial to mesenchymal transition	GO:0001837	47	0.098
developmental programmed cell death	GO:0010623	41	0.098
ameboidal type cell migration	GO:0001667	128	0.097
regulation of fat cell differentiation	GO:0045598	81	0.097
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration	GO:0014834	3	0.096
regeneration	GO:0031099	38	0.096
regulation of system process	GO:0044057	200	0.095
mitral valve development	GO:0003174	4	0.095
development of primary male sexual characteristics	GO:0046546	88	0.095
cartilage development	GO:0051216	140	0.095
muscle cell development	GO:0055001	133	0.095
gonad development	GO:0008406	141	0.095
positive regulation of cell cycle	GO:0045787	92	0.095
thyroid stimulating hormone secreting cell differentiation	GO:0060129	4	0.094
b cell activation	GO:0042113	161	0.093
septum primum development	GO:0003284	4	0.091
morphogenesis of embryonic epithelium	GO:0016331	159	0.091
hemangioblast cell differentiation	GO:0060217	1	0.090
spinal cord motor neuron cell fate specification	GO:0021520	13	0.090
peripheral nervous system neuron axonogenesis	GO:0048936	3	0.090
somite development	GO:0061053	81	0.089
motor neuron migration	GO:0097475	4	0.089
somitogenesis	GO:0001756	69	0.089
neuroepithelial cell differentiation	GO:0060563	37	0.089
regulation of mast cell differentiation	GO:0060375	3	0.089
mesonephric tubule development	GO:0072164	94	0.089
oviduct development	GO:0060066	3	0.088
smoothened signaling pathway	GO:0007224	105	0.087
ventral spinal cord interneuron fate commitment	GO:0060579	14	0.087
meiotic cell cycle	GO:0051321	122	0.086
regulation of ossification	GO:0030278	112	0.086
positive regulation of cell death	GO:0010942	224	0.086
neural tube closure	GO:0001843	90	0.085
forelimb morphogenesis	GO:0035136	40	0.085
protein import into nucleus	GO:0006606	95	0.084
guanosine containing compound catabolic process	GO:1901069	144	0.083
heart growth	GO:0060419	45	0.083
regulation of transcription from rna polymerase iii promoter	GO:0006359	2	0.082
postsynaptic membrane organization	GO:0001941	18	0.082	Mouse
nuclear transport	GO:0051169	139	0.081
regulation of morphogenesis of a branching structure	GO:0060688	53	0.081
transdifferentiation	GO:0060290	1	0.081
positive regulation of synaptic plasticity	GO:0031915	4	0.081
inner ear morphogenesis	GO:0042472	101	0.081
protein modification by small protein conjugation or removal	GO:0070647	207	0.080
multicellular organism growth	GO:0035264	161	0.080
limb development	GO:0060173	166	0.080	Zebrafish
metanephric loop of henle development	GO:0072236	4	0.080
regulation of cytokine production	GO:0001817	266	0.080
paraxial mesodermal cell fate commitment	GO:0048343	2	0.078
histone modification	GO:0016570	159	0.078
pancreatic a cell fate commitment	GO:0003326	2	0.078
embryonic limb morphogenesis	GO:0030326	126	0.078
regulation of auditory receptor cell differentiation	GO:0045607	4	0.078
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation	GO:2000800	1	0.077
cell type specific apoptotic process	GO:0097285	268	0.077
negative regulation of gastrulation	GO:2000542	3	0.077
organophosphate biosynthetic process	GO:0090407	122	0.077
regulation of bmp signaling pathway	GO:0030510	60	0.077
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.076
cerebellar granule cell precursor proliferation	GO:0021930	10	0.076
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.076
connective tissue development	GO:0061448	179	0.076
regulation of endothelial cell differentiation	GO:0045601	10	0.076	Mouse
dendrite development	GO:0016358	115	0.076
midbrain development	GO:0030901	35	0.075
cation transport	GO:0006812	399	0.075
artery development	GO:0060840	53	0.075
astrocyte differentiation	GO:0048708	43	0.074
auditory receptor cell differentiation	GO:0042491	37	0.074
cell proliferation in hindbrain	GO:0021534	10	0.073
response to organic cyclic compound	GO:0014070	198	0.072
myeloid cell differentiation	GO:0030099	233	0.072	Mouse
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.072
telencephalon development	GO:0021537	186	0.072
divalent inorganic cation transport	GO:0072511	178	0.071
b cell differentiation	GO:0030183	78	0.071
lens development in camera type eye	GO:0002088	62	0.071
nucleobase containing small molecule metabolic process	GO:0055086	352	0.070
prostate gland morphogenesis	GO:0060512	32	0.070
forebrain neuron development	GO:0021884	30	0.070
cranial nerve development	GO:0021545	41	0.070
cellular response to lipid	GO:0071396	145	0.070
organ growth	GO:0035265	117	0.070
negative regulation of mammary gland epithelial cell proliferation	GO:0033600	3	0.070
regulation of wnt signaling pathway	GO:0030111	123	0.069
keratinocyte differentiation	GO:0030216	48	0.069
regulation of kinase activity	GO:0043549	249	0.069
single organism nuclear import	GO:1902593	95	0.069
glycosyl compound metabolic process	GO:1901657	246	0.069
paramesonephric duct development	GO:0061205	3	0.068
endoderm development	GO:0007492	45	0.068
cardiac muscle cell differentiation	GO:0055007	69	0.068
dentate gyrus development	GO:0021542	14	0.068
purine ribonucleotide metabolic process	GO:0009150	290	0.068
synapse organization	GO:0050808	125	0.067	Mouse
protein modification by small protein conjugation	GO:0032446	187	0.067
asymmetric stem cell division	GO:0098722	3	0.067
compound eye development	GO:0048749	1	0.066
regulation of organ formation	GO:0003156	34	0.066
morphogenesis of an epithelial sheet	GO:0002011	27	0.066
transforming growth factor beta receptor signaling pathway	GO:0007179	71	0.066
morphogenesis of a polarized epithelium	GO:0001738	37	0.066
regulation of osteoblast differentiation	GO:0045667	67	0.066
cellular lipid metabolic process	GO:0044255	323	0.065
adenohypophysis development	GO:0021984	14	0.065
mitotic cell cycle	GO:0000278	195	0.065
regulation of neural retina development	GO:0061074	3	0.065
apoptotic signaling pathway	GO:0097190	306	0.065
negative regulation of sequence specific dna binding transcription factor activity	GO:0043433	40	0.064
positive regulation of mapk cascade	GO:0043410	170	0.064
tissue regeneration	GO:0042246	22	0.064
regulation of cell motility	GO:2000145	236	0.064
positive regulation of stem cell proliferation	GO:2000648	59	0.064
pituitary gland development	GO:0021983	38	0.064
embryonic skeletal system development	GO:0048706	120	0.064
cellular carbohydrate metabolic process	GO:0044262	119	0.063
negative regulation of molecular function	GO:0044092	258	0.063
establishment of neuroblast polarity	GO:0045200	1	0.063
pancreatic pp cell fate commitment	GO:0003329	2	0.063
regulation of asymmetric cell division	GO:0009786	4	0.063
peptidyl tyrosine phosphorylation	GO:0018108	143	0.062
hypophysis morphogenesis	GO:0048850	3	0.062
male sex differentiation	GO:0046661	109	0.062
embryonic skeletal system morphogenesis	GO:0048704	91	0.062
peripheral nervous system development	GO:0007422	53	0.062
planar cell polarity pathway involved in pericardium morphogenesis	GO:0061354	2	0.061
nuclear division	GO:0000280	158	0.061
labyrinthine layer development	GO:0060711	49	0.061
regulation of transmembrane transport	GO:0034762	128	0.061
bone morphogenesis	GO:0060349	78	0.061
bone development	GO:0060348	120	0.061
protein localization to nucleus	GO:0034504	121	0.061
regulation of peptidyl serine phosphorylation	GO:0033135	39	0.061
canonical wnt signaling pathway involved in regulation of cell proliferation	GO:0044340	3	0.061
neuron maturation	GO:0042551	29	0.061	Mouse
catecholamine metabolic process	GO:0006584	30	0.060
extracellular structure organization	GO:0043062	148	0.060
tendon cell differentiation	GO:0035990	4	0.060
regulation of chromosome organization	GO:0033044	83	0.060
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.060
nucleoside triphosphate catabolic process	GO:0009143	205	0.060
cardiac septum morphogenesis	GO:0060411	46	0.060
asymmetric neuroblast division	GO:0055059	1	0.059
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.059
cell substrate adhesion	GO:0031589	130	0.059
positive regulation of transferase activity	GO:0051347	167	0.059
development of primary female sexual characteristics	GO:0046545	73	0.059
negative regulation of cell fate specification	GO:0009996	4	0.059
negative regulation of cellular protein metabolic process	GO:0032269	247	0.059
cytokine production	GO:0001816	319	0.059
negative regulation of neuron projection development	GO:0010977	50	0.059
regulation of establishment of planar polarity involved in neural tube closure	GO:0090178	15	0.059
spinal cord development	GO:0021510	81	0.058
cardiac cell fate specification	GO:0060912	2	0.058
peptidyl tyrosine modification	GO:0018212	145	0.058
cardiac right atrium morphogenesis	GO:0003213	3	0.058
negative regulation of growth	GO:0045926	99	0.058
cell proliferation involved in heart valve development	GO:2000793	2	0.058
motor neuron axon guidance	GO:0008045	26	0.057
regulation of protein kinase activity	GO:0045859	232	0.057
protein localization to membrane	GO:0072657	108	0.057	Mouse
positive regulation of neuron differentiation	GO:0045666	141	0.057
covalent chromatin modification	GO:0016569	163	0.057
pancreatic pp cell differentiation	GO:0003312	2	0.057
non canonical wnt signaling pathway	GO:0035567	33	0.057
purine ribonucleotide catabolic process	GO:0009154	208	0.056
purine containing compound metabolic process	GO:0072521	311	0.056
oligodendrocyte differentiation	GO:0048709	53	0.056
aortic valve morphogenesis	GO:0003180	4	0.056
regulation of secretion	GO:0051046	274	0.056
regulation of stem cell differentiation	GO:2000736	50	0.056
cell surface receptor signaling pathway involved in heart development	GO:0061311	15	0.056
glandular epithelial cell differentiation	GO:0002067	38	0.055
establishment of planar polarity involved in neural tube closure	GO:0090177	15	0.055
cerebral cortex neuron differentiation	GO:0021895	19	0.054
epithelial cell morphogenesis	GO:0003382	41	0.054
protein ubiquitination	GO:0016567	171	0.054
carbon catabolite repression of transcription from rna polymerase ii promoter	GO:0000437	1	0.053
cardiac atrium morphogenesis	GO:0003209	23	0.053
regulation of cellular response to stress	GO:0080135	159	0.053
cardiac epithelial to mesenchymal transition	GO:0060317	18	0.053
positive regulation of fat cell differentiation	GO:0045600	32	0.053
respiratory system development	GO:0060541	190	0.053
regulation of retina development in camera type eye	GO:1902866	3	0.053
wnt signaling pathway involved in forebrain neuroblast division	GO:0021874	2	0.052
negative regulation of prostatic bud formation	GO:0060686	4	0.052
ectoderm formation	GO:0001705	3	0.052
associative learning	GO:0008306	61	0.052
renal system development	GO:0072001	225	0.052	Zebrafish
positive regulation of cell motility	GO:2000147	116	0.052
neuron fate specification	GO:0048665	30	0.052	Mouse
visceral serous pericardium development	GO:0061032	2	0.051
regulation of neural precursor cell proliferation	GO:2000177	70	0.051
prostate gland epithelium morphogenesis	GO:0060740	31	0.051
liver development	GO:0001889	66	0.051
tissue remodeling	GO:0048771	102	0.051
regulation of muscle system process	GO:0090257	80	0.051
determination of left right symmetry	GO:0007368	80	0.051
carbohydrate derivative catabolic process	GO:1901136	231	0.050
deltoid tuberosity development	GO:0035993	3	0.050
striated muscle cell development	GO:0055002	125	0.050
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.050
regulation of mitotic cell cycle	GO:0007346	126	0.050
mesodermal cell fate specification	GO:0007501	11	0.050	Mouse
methylation	GO:0032259	134	0.049
regulation of cartilage development	GO:0061035	44	0.049
regulation of serotonin secretion	GO:0014062	3	0.049
positive regulation of interleukin 1 alpha production	GO:0032730	4	0.049
response to extracellular stimulus	GO:0009991	127	0.049
regulation of cell cycle process	GO:0010564	160	0.049
negative regulation of cell cycle	GO:0045786	123	0.049
regulation of neuron death	GO:1901214	134	0.049
keratinocyte proliferation	GO:0043616	21	0.049
embryonic camera type eye development	GO:0031076	36	0.048
divalent metal ion transport	GO:0070838	172	0.048
cell differentiation in spinal cord	GO:0021515	53	0.048
central nervous system neuron development	GO:0021954	67	0.048
cognition	GO:0050890	149	0.048
regulation of ras protein signal transduction	GO:0046578	114	0.048
microtubule based process	GO:0007017	236	0.048
wound healing	GO:0042060	157	0.047
cardiac muscle tissue growth	GO:0055017	37	0.047
neuron apoptotic process	GO:0051402	142	0.047
tendon formation	GO:0035992	4	0.047
regulation of stem cell proliferation	GO:0072091	78	0.047
planar cell polarity pathway involved in heart morphogenesis	GO:0061346	3	0.047
regulation of establishment of protein localization	GO:0070201	181	0.047
axis elongation	GO:0003401	30	0.047
metencephalon development	GO:0022037	89	0.047
developmental cell growth	GO:0048588	84	0.046
wnt signaling pathway planar cell polarity pathway	GO:0060071	27	0.046
negative regulation of glial cell differentiation	GO:0045686	21	0.046
positive regulation of ossification	GO:0045778	47	0.046
cell proliferation in external granule layer	GO:0021924	10	0.046
lung morphogenesis	GO:0060425	50	0.046
nucleoside triphosphate metabolic process	GO:0009141	230	0.046
regulation of tube size	GO:0035150	57	0.046
negative regulation of protein modification process	GO:0031400	163	0.046
regulation of cellular catabolic process	GO:0031329	242	0.046
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis	GO:2000764	1	0.045
ribonucleotide metabolic process	GO:0009259	291	0.045
ribonucleotide biosynthetic process	GO:0009260	59	0.045
learning	GO:0007612	98	0.045
nuclear import	GO:0051170	95	0.045
regulation of ion transmembrane transport	GO:0034765	119	0.045
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.044
cerebellum formation	GO:0021588	1	0.044
neuroblast proliferation	GO:0007405	49	0.044
protein secretion	GO:0009306	111	0.044
tissue homeostasis	GO:0001894	115	0.044
leukocyte differentiation	GO:0002521	342	0.044
peptide hormone secretion	GO:0030072	109	0.044
bmp signaling pathway involved in mesodermal cell fate specification	GO:0060803	1	0.044	Mouse
somatotropin secreting cell differentiation	GO:0060126	4	0.044
protein import	GO:0017038	101	0.044
establishment of protein localization to organelle	GO:0072594	118	0.044
kidney epithelium development	GO:0072073	121	0.044
negative regulation of apoptotic process involved in outflow tract morphogenesis	GO:1902257	2	0.043
heterocycle catabolic process	GO:0046700	280	0.043
endomembrane system organization	GO:0010256	147	0.043
regulation of meiotic cell cycle	GO:0051445	34	0.043
spemann organizer formation	GO:0060061	2	0.043
regulation of cellular response to growth factor stimulus	GO:0090287	82	0.043
glucose homeostasis	GO:0042593	128	0.043
somatic stem cell maintenance	GO:0035019	47	0.042
negative regulation of gliogenesis	GO:0014014	23	0.042
cerebellar cortex formation	GO:0021697	22	0.042
long term synaptic potentiation	GO:0060291	25	0.042
mesenchyme morphogenesis	GO:0072132	32	0.042
ribonucleoside metabolic process	GO:0009119	245	0.042
placenta blood vessel development	GO:0060674	31	0.042
negative regulation of oxidative phosphorylation uncoupler activity	GO:2000276	2	0.042
eye photoreceptor cell differentiation	GO:0001754	41	0.042
regulation of anatomical structure size	GO:0090066	178	0.042
regulation of nucleoside metabolic process	GO:0009118	130	0.042

Etv4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org

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