Mus musculus

107 known processes

Eif4g3

eukaryotic translation initiation factor 4 gamma, 3

(Aliases: G1-419-52,4930523M17Rik,4833436O05,repro8,1500002J22Rik,eIF4GII)

Eif4g3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organic cyclic compound catabolic processGO:19013612950.076
spermatogenesisGO:00072832840.074
covalent chromatin modificationGO:00165691630.073
nucleoside phosphate metabolic processGO:00067533380.073
purine containing compound catabolic processGO:00725232130.067
male gamete generationGO:00482322850.065
dna metabolic processGO:00062593030.061
purine containing compound metabolic processGO:00725213110.059
macromolecule catabolic processGO:00090572810.057
chromatin organizationGO:00063252060.056
chromatin modificationGO:00165681870.053
cellular protein catabolic processGO:00442571550.048
purine ribonucleoside metabolic processGO:00461282410.047
nucleobase containing small molecule metabolic processGO:00550863520.046
purine ribonucleoside triphosphate metabolic processGO:00092052200.046
modification dependent protein catabolic processGO:00199411330.045
ribose phosphate metabolic processGO:00196932910.044
negative regulation of intracellular signal transductionGO:19025321670.043
olfactory learningGO:000835520.043
nucleoside catabolic processGO:00091642060.043
nucleotide metabolic processGO:00091173320.043
carbohydrate metabolic processGO:00059752300.043
regulation of cellular amino acid metabolic processGO:000652150.041
protein ubiquitinationGO:00165671710.041
regulation of organelle organizationGO:00330432890.041
regulation of cellular component sizeGO:00325351210.041
regulation of anatomical structure sizeGO:00900661780.041
ribonucleoside triphosphate metabolic processGO:00091992200.040
protein modification by small protein conjugationGO:00324461870.040
regulation of hydrolase activityGO:00513362460.040
ribonucleotide metabolic processGO:00092592910.039
aromatic compound catabolic processGO:00194392860.039
purine nucleotide catabolic processGO:00061952110.039
negative regulation of phosphate metabolic processGO:00459361840.039
cellular nitrogen compound catabolic processGO:00442702800.039
glycosyl compound metabolic processGO:19016572460.038
negative regulation of cellular protein metabolic processGO:00322692470.038
ubiquitin dependent protein catabolic processGO:00065111290.037
protein modification by small protein conjugation or removalGO:00706472070.037
cellular amino acid metabolic processGO:00065201030.037
purine ribonucleoside triphosphate catabolic processGO:00092071990.036
homeostasis of number of cellsGO:00488722100.036
chemotaxisGO:00069352470.036
glycosyl compound catabolic processGO:19016582060.035
ribonucleoside catabolic processGO:00424542060.035
cellular protein complex assemblyGO:00436231160.034
small gtpase mediated signal transductionGO:0007264970.034
organonitrogen compound catabolic processGO:19015652640.034
purine ribonucleoside catabolic processGO:00461302050.033
negative regulation of protein metabolic processGO:00512482820.033
ribonucleotide catabolic processGO:00092612080.033
nucleoside triphosphate catabolic processGO:00091432050.033
negative regulation of cell developmentGO:00107211690.033
posttranscriptional regulation of gene expressionGO:00106081550.033
nucleoside phosphate catabolic processGO:19012922220.033
histone modificationGO:00165701590.032
purine ribonucleotide metabolic processGO:00091502900.032
cellular macromolecule catabolic processGO:00442652060.032
organelle assemblyGO:00709251770.032
regulation of nucleotide metabolic processGO:00061401690.032
negative regulation of cellular component organizationGO:00511291940.032
ribonucleoside metabolic processGO:00091192450.032
purine nucleotide metabolic processGO:00061633020.031
negative regulation of synapse assemblyGO:005196430.031
synaptic transmissionGO:00072683290.031
positive regulation of cellular catabolic processGO:00313311480.031
nucleoside metabolic processGO:00091162460.030
nucleotide catabolic processGO:00091662170.030
cilium assemblyGO:0042384810.030
germ cell developmentGO:00072811850.030
regulation of purine nucleotide catabolic processGO:00331211220.030
cellular ketone metabolic processGO:0042180840.029
nucleosome disassemblyGO:000633710.029
protein catabolic processGO:00301632210.029
regulation of cellular amine metabolic processGO:0033238200.029
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.029
protein localization to organelleGO:00333651850.029
gtp metabolic processGO:00460391440.029
forebrain developmentGO:00309003020.029
microtubule severingGO:005101350.028
mitotic cell cycle processGO:19030471590.028
cellular amine metabolic processGO:0044106440.028
axonogenesisGO:00074092740.028
negative regulation of nervous system developmentGO:00519611560.028
regulation of cell cycleGO:00517262810.028
cellular response to biotic stimulusGO:0071216920.028
proteolysis involved in cellular protein catabolic processGO:00516031470.027
negative regulation of molecular functionGO:00440922580.027
compound eye developmentGO:004874910.027
ribonucleoside triphosphate catabolic processGO:00092031990.027
regulation of cellular ketone metabolic processGO:0010565660.027
skeletal system developmentGO:00015013560.027
chromatin disassemblyGO:003149810.027
regulation of nucleoside metabolic processGO:00091181300.026
purine nucleoside triphosphate metabolic processGO:00091442260.026
purine nucleoside triphosphate catabolic processGO:00091462030.026
sequestering of metal ionGO:0051238190.026
microtubule cytoskeleton organizationGO:00002261570.026
guanosine containing compound metabolic processGO:19010681440.026
amine metabolic processGO:0009308450.025
regulation of cellular catabolic processGO:00313292420.025
carbohydrate derivative catabolic processGO:19011362310.025
positive regulation of cellular amine metabolic processGO:003324050.025
regulation of cytoskeleton organizationGO:00514931220.025
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.025
translationGO:0006412930.025
regulation of cell projection organizationGO:00313442060.025
transmembrane transportGO:00550854120.024
positive regulation of cellular amino acid metabolic processGO:004576430.024
microtubule based processGO:00070172360.024
regulation of synaptic growth at neuromuscular junctionGO:000858240.024
nucleoside triphosphate metabolic processGO:00091412300.024
regulation of purine nucleotide metabolic processGO:19005421690.024
negative regulation of cellular amine metabolic processGO:003323910.024
cell divisionGO:00513011200.024
cytoplasmic transportGO:00164822340.024
leukocyte differentiationGO:00025213420.024
cellular response to dna damage stimulusGO:00069742070.024
endocytosisGO:00068971680.024
myeloid cell differentiationGO:00300992330.023
nuclear divisionGO:00002801580.023
protein processingGO:00164851630.023
locomotory behaviorGO:00076261950.023
spermatid developmentGO:00072861080.023
regulation of membrane potentialGO:00423911920.023
macromolecular complex disassemblyGO:0032984430.023
ras protein signal transductionGO:0007265770.023
apoptotic signaling pathwayGO:00971903060.023
central nervous system neuron differentiationGO:00219531620.023
purine ribonucleotide catabolic processGO:00091542080.023
positive regulation of nucleotide metabolic processGO:00459811140.023
cellular response to organonitrogen compoundGO:00714171450.022
spermatid differentiationGO:00485151150.022
endomembrane system organizationGO:00102561470.022
regulation of defense responseGO:00313472330.022
regulation of cell growthGO:0001558910.022
muscle tissue developmentGO:00605373080.022
positive regulation of hydrolase activityGO:00513451480.022
purine nucleoside metabolic processGO:00422782410.022
regulation of mapk cascadeGO:00434082480.022
positive regulation of nucleotide catabolic processGO:0030813880.021
actin cytoskeleton organizationGO:00300362200.021
regulation of protein complex assemblyGO:0043254830.021
regulation of cell cycle processGO:00105641600.021
membrane organizationGO:00610242450.021
cation transportGO:00068123990.021
neuron projection guidanceGO:00974851410.021
heterocycle catabolic processGO:00467002800.021
peptidyl amino acid modificationGO:00181933360.021
t cell activationGO:00421102890.021
regulation of cellular component biogenesisGO:00440871810.021
cellular homeostasisGO:00197252400.021
intracellular protein transportGO:00068862040.021
response to organonitrogen compoundGO:00102432460.021
cytokine productionGO:00018163190.021
regionalizationGO:00030023370.020
mitotic cell cycleGO:00002781950.020
camera type eye developmentGO:00430102660.020
dna repairGO:00062811070.020
blood vessel morphogenesisGO:00485142850.020
modification dependent macromolecule catabolic processGO:00436321330.020
embryonic organ morphogenesisGO:00485622760.020
actin filament polymerizationGO:0030041440.020
positive regulation of apoptotic processGO:00430652170.019
negative regulation of phosphorylationGO:00423261660.019
learning or memoryGO:00076111480.019
positive regulation of dna templated transcription elongationGO:003278620.019
positive regulation of nucleoside metabolic processGO:0045979910.019
cellular response to lipidGO:00713961450.019
positive regulation of ras gtpase activityGO:0032320650.019
actin polymerization or depolymerizationGO:0008154540.019
regulation of cytokine productionGO:00018172660.019
rho protein signal transductionGO:0007266320.019
meiotic nuclear divisionGO:00071261150.019
negative regulation of phosphorus metabolic processGO:00105631840.019
activation of immune responseGO:00022531380.018
sequestering of calcium ionGO:0051208180.018
organophosphate catabolic processGO:00464342320.018
nitrogen compound transportGO:00717052710.018
protein maturationGO:00516041760.018
regulation of nucleotide catabolic processGO:00308111220.018
negative regulation of growthGO:0045926990.018
positive regulation of purine nucleotide metabolic processGO:19005441140.018
negative regulation of cell proliferationGO:00082852960.018
divalent metal ion transportGO:00708381720.018
regulation of neuron differentiationGO:00456642810.018
habituationGO:004695930.018
mapk cascadeGO:00001652810.018
positive regulation of protein phosphorylationGO:00019342420.018
purine nucleoside catabolic processGO:00061522050.018
protein dna complex disassemblyGO:003298610.018
cognitionGO:00508901490.018
regulation of cell morphogenesis involved in differentiationGO:00107691510.018
gene silencingGO:0016458380.018
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600330.018
regulation of cell motilityGO:20001452360.017
epithalamus developmentGO:002153820.017
response to lipopolysaccharideGO:00324961280.017
microtubule based movementGO:0007018840.017
regulation of sequence specific dna binding transcription factor activityGO:00510901060.017
anion transportGO:00068201770.017
transmission of nerve impulseGO:0019226760.017
immune effector processGO:00022523210.017
positive regulation of purine nucleotide catabolic processGO:0033123880.017
regulation of proteolysisGO:00301621640.017
dna recombinationGO:0006310920.017
regulation of protein localizationGO:00328802310.017
protein complex disassemblyGO:0043241400.017
positive regulation of nervous system developmentGO:00519622210.017
exocytosisGO:00068871210.017
mitochondrion distributionGO:004831140.017
regulation of apoptotic signaling pathwayGO:20012331970.016
nuclear transportGO:00511691390.016
histone acetylationGO:0016573410.016
regulation of cell sizeGO:0008361720.016
regulation of wnt signaling pathwayGO:00301111230.016
organelle fissionGO:00482851700.016
positive regulation of defense responseGO:00313491240.016
regulation of homeostatic processGO:00328441820.016
neural tube developmentGO:00219151600.016
muscle cell differentiationGO:00426922610.016
dephosphorylationGO:00163111290.016
regulation of cellular response to stressGO:00801351590.016
extracellular structure organizationGO:00430621480.015
guanosine containing compound catabolic processGO:19010691440.015
cellular component assembly involved in morphogenesisGO:00109271390.015
cell growthGO:00160491300.015
production of molecular mediator of immune responseGO:00024401030.015
carbohydrate derivative biosynthetic processGO:19011371830.015
divalent inorganic cation transportGO:00725111780.015
neuron deathGO:00709971540.015
cellular response to molecule of bacterial originGO:0071219830.015
regulation of protein catabolic processGO:00421761080.015
axon guidanceGO:00074111410.015
axon cargo transportGO:0008088330.015
maintenance of locationGO:0051235890.015
wnt signaling pathwayGO:00160551880.015
protein polymerizationGO:0051258570.014
meiotic cell cycleGO:00513211220.014
regulation of neuron deathGO:19012141340.014
cellular chemical homeostasisGO:00550822150.014
organonitrogen compound biosynthetic processGO:19015661920.014
protein acylationGO:0043543640.014
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.014
nucleoside monophosphate metabolic processGO:0009123850.014
nucleocytoplasmic transportGO:00069131390.014
cell adhesionGO:00071553290.014
cell type specific apoptotic processGO:00972852680.014
regulation of protein stabilityGO:0031647520.014
chromatin remodelingGO:0006338320.014
positive regulation of gtpase activityGO:0043547850.014
cell fate commitmentGO:00451652100.014
regulation of lymphocyte activationGO:00512492400.014
vesicle organizationGO:0016050600.014
central nervous system projection neuron axonogenesisGO:0021952210.014
terminal button organizationGO:007255330.014
positive regulation of bindingGO:0051099490.014
gtp catabolic processGO:00061841430.014
regulation of neuron projection developmentGO:00109751690.014
cellular metal ion homeostasisGO:00068751510.014
positive regulation of cell developmentGO:00107202370.014
gland developmentGO:00487323300.014
negative regulation of immune system processGO:00026832090.013
ribonucleoside monophosphate metabolic processGO:0009161800.013
single organism nuclear importGO:1902593950.013
telencephalon developmentGO:00215371860.013
cation transmembrane transportGO:00986552660.013
regulation of system processGO:00440572000.013
regulation of multi organism processGO:00439001110.013
gliogenesisGO:00420631410.013
regulation of reactive oxygen species biosynthetic processGO:190342620.013
regulation of clathrin mediated endocytosisGO:200036940.013
regulation of secretionGO:00510462740.013
organic hydroxy compound metabolic processGO:19016152030.013
histone methylationGO:0016571710.013
hatchingGO:003518840.013
striated muscle tissue developmentGO:00147062930.013
second messenger mediated signalingGO:0019932730.013
learningGO:0007612980.013
smoothened signaling pathwayGO:00072241050.013
positive regulation of macroautophagyGO:001623930.013
lipid localizationGO:00108761260.013
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.013
regulation of extent of cell growthGO:0061387520.013
regulation of vesicle mediated transportGO:00606271390.013
memoryGO:0007613580.013
negative regulation of bmp signaling pathwayGO:0030514350.013
hindbrain developmentGO:00309021280.013
response to molecule of bacterial originGO:00022371430.013
negative regulation of protein modification processGO:00314001630.013
engulfment of apoptotic cellGO:004365230.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.012
cilium morphogenesisGO:00602711020.012
internal peptidyl lysine acetylationGO:0018393420.012
tube formationGO:00351481400.012
regulation of ras protein signal transductionGO:00465781140.012
inorganic cation transmembrane transportGO:00986622070.012
developmental growth involved in morphogenesisGO:00605601380.012
neuron migrationGO:00017641220.012
development of primary sexual characteristicsGO:00451371430.012
regulation of translationGO:0006417710.012
dorsal ventral axon guidanceGO:003356330.012
divalent inorganic cation homeostasisGO:00725071380.012
response to radiationGO:00093141650.012
regulation of protein kinase activityGO:00458592320.012
carbohydrate homeostasisGO:00335001280.012
cellular response to organic cyclic compoundGO:0071407870.012
positive regulation of gtp catabolic processGO:0033126850.012
negative regulation of cellular amino acid metabolic processGO:004576300.012
negative regulation of gene silencingGO:006096920.012
positive regulation of neuron differentiationGO:00456661410.012
cellular response to lipopolysaccharideGO:0071222770.012
cellular lipid metabolic processGO:00442553230.012
regulation of terminal button organizationGO:200033110.012
regulation of kinase activityGO:00435492490.012
regulation of actin cytoskeleton organizationGO:0032956840.012
sensory organ morphogenesisGO:00905962420.012
reactive oxygen species metabolic processGO:0072593840.012
negative regulation of multi organism processGO:0043901680.012
regulation of protein transportGO:00512231630.012
neuromuscular processGO:0050905990.012
phagocytosisGO:0006909660.012
regulation of actin filament based processGO:0032970990.012
neuron apoptotic processGO:00514021420.012
embryonic epithelial tube formationGO:00018381300.012
rhythmic processGO:00485111740.012
atp metabolic processGO:0046034750.012
extracellular matrix organizationGO:00301981470.012
regulation of reactive oxygen species metabolic processGO:2000377400.012
regulation of transferase activityGO:00513382630.012
lipid biosynthetic processGO:00086101790.012
positive regulation of neuron projection developmentGO:0010976790.012
interspecies interaction between organismsGO:0044419830.012
lipid transportGO:0006869980.012
regulation of secretion by cellGO:19035302490.012
peptidyl lysine modificationGO:0018205770.012
ion transmembrane transportGO:00342203610.011
pharynx developmentGO:006046510.011
asymmetric stem cell divisionGO:009872230.011
immune response regulating signaling pathwayGO:00027641250.011
proteasomal protein catabolic processGO:0010498980.011
developmental maturationGO:00217001930.011
inorganic ion transmembrane transportGO:00986602340.011
protein localization to plasma membraneGO:0072659570.011
gene silencing by mirnaGO:0035195100.011
developmental cell growthGO:0048588840.011
cytoskeleton dependent intracellular transportGO:0030705500.011
positive regulation of actin nucleationGO:005112730.011
pigmentationGO:0043473710.011
cellular response to cytokine stimulusGO:00713451890.011
regulation of transmembrane transportGO:00347621280.011
neuronal action potentialGO:0019228540.011
cardiac chamber developmentGO:00032051080.011
glial cell differentiationGO:00100011310.011
regulation of rho protein signal transductionGO:0035023710.011
lateral inhibitionGO:004633110.011
cellular response to growth factor stimulusGO:00713631970.011
establishment or maintenance of cytoskeleton polarityGO:003095220.011
response to growth factorGO:00708481980.011
single organism cell adhesionGO:00986021560.011
lung developmentGO:00303241640.011
regulation of actin filament lengthGO:0030832450.011
regulation of gtp catabolic processGO:00331241130.011
regulation of protein processingGO:0070613960.011
negative regulation of neuron projection developmentGO:0010977500.011
negative regulation of glial cell proliferationGO:006025340.011
humoral immune responseGO:0006959570.011
glucose homeostasisGO:00425931280.011
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.011
action potentialGO:0001508780.011
regulation of t cell activationGO:00508631700.011
macromolecule methylationGO:00434141200.011
midgut developmentGO:000749440.011
cell substrate adhesionGO:00315891300.011
vesicle localizationGO:0051648860.011
connective tissue developmentGO:00614481790.011
negative regulation of organelle organizationGO:0010639900.011
neuroblast fate commitmentGO:001401710.011
associative learningGO:0008306610.011
regulation of chromosome organizationGO:0033044830.011
regulation of hippo signalingGO:003533010.011
regulation of cell migrationGO:00303342190.011
regulation of actin nucleationGO:005112540.011
establishment of protein localization to organelleGO:00725941180.011
golgi vesicle transportGO:0048193300.011
localization within membraneGO:005166840.011
negative regulation of cytokine productionGO:0001818840.011
cell recognitionGO:0008037830.011
plasma membrane organizationGO:0007009900.011
rna processingGO:00063961050.011
negative regulation of neuron apoptotic processGO:0043524920.011
regulation of cell activationGO:00508652890.011
purine ribonucleoside monophosphate metabolic processGO:0009167800.010
regulation of leukocyte differentiationGO:19021051590.010
respiratory tube developmentGO:00303231670.010
multicellular organismal signalingGO:0035637910.010
myotube differentiationGO:00149021050.010
regulation of map kinase activityGO:00434051200.010
lymphocyte differentiationGO:00300982420.010
myosin filament assemblyGO:003103420.010
hematopoietic progenitor cell differentiationGO:00022441430.010
adult behaviorGO:00305341350.010
neural precursor cell proliferationGO:00613511210.010
endodermal cell fate specificationGO:000171440.010
negative regulation of chromatin silencingGO:003193610.010
regulation of voltage gated calcium channel activityGO:190138540.010
regulation of bmp signaling pathwayGO:0030510600.010
chondrocyte differentiationGO:0002062720.010
regulation of establishment of protein localizationGO:00702011810.010
b cell activationGO:00421131610.010
regulation of chromatin organizationGO:1902275570.010
negative regulation of cell morphogenesis involved in differentiationGO:0010771480.010
anatomical structure homeostasisGO:00602491450.010
intrinsic apoptotic signaling pathwayGO:00971931320.010
histone h4 k16 acetylationGO:004398430.010
organic anion transportGO:00157111370.010
cellular ion homeostasisGO:00068731650.010
lymphocyte mediated immunityGO:00024491390.010
skeletal system morphogenesisGO:00487052030.010
positive regulation of transferase activityGO:00513471670.010
organic hydroxy compound transportGO:0015850930.010
regulation of axon extensionGO:0030516430.010

Eif4g3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
nervous system diseaseDOID:86300.030
central nervous system diseaseDOID:33100.021
organ system cancerDOID:005068600.020
disease of cellular proliferationDOID:1456600.020
cancerDOID:16200.020
musculoskeletal system diseaseDOID:1700.017
immune system diseaseDOID:291400.016
connective tissue diseaseDOID:6500.012
disease of mental healthDOID:15000.012
hematopoietic system diseaseDOID:7400.012