IMP: Integrative Multi-species Prediction

Mus musculus

95 known processes

Zfp35

zinc finger protein 35

(Aliases: mszf68,mszf13,mszf20-1,Znf271,mszf28,Zfp-35)

Entrez: 22694
Ensembl: ENSMUSG00000063281
UniProtKB: Q3V142
UniProtKB: P15620

Process Predictions
Disease Predictions

Zfp35 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
covalent chromatin modification	GO:0016569	163	0.048
cellular amino acid metabolic process	GO:0006520	103	0.042
regulation of cellular amino acid metabolic process	GO:0006521	5	0.040
cellular amine metabolic process	GO:0044106	44	0.040
cellular ketone metabolic process	GO:0042180	84	0.039
regulation of cellular amine metabolic process	GO:0033238	20	0.038
immune effector process	GO:0002252	321	0.038
rna processing	GO:0006396	105	0.036
methylation	GO:0032259	134	0.035
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.034
regulation of cellular ketone metabolic process	GO:0010565	66	0.034
leukocyte differentiation	GO:0002521	342	0.032
dna metabolic process	GO:0006259	303	0.031
macromolecule methylation	GO:0043414	120	0.030
amine metabolic process	GO:0009308	45	0.029
histone modification	GO:0016570	159	0.028
organelle fission	GO:0048285	170	0.027
mitotic chromosome condensation	GO:0007076	1	0.026
negative regulation of molecular function	GO:0044092	258	0.026
positive regulation of cellular amine metabolic process	GO:0033240	5	0.026
microtubule based process	GO:0007017	236	0.024
regulation of organelle organization	GO:0033043	289	0.022
lymphocyte activation involved in immune response	GO:0002285	93	0.022
lymphocyte differentiation	GO:0030098	242	0.022
leukocyte mediated immunity	GO:0002443	174	0.021
chromatin modification	GO:0016568	187	0.021
leukocyte activation involved in immune response	GO:0002366	126	0.020
chromatin organization	GO:0006325	206	0.020
mitotic cell cycle	GO:0000278	195	0.020
cell type specific apoptotic process	GO:0097285	268	0.019
t cell activation	GO:0042110	289	0.019
protein localization to organelle	GO:0033365	185	0.019
cell activation involved in immune response	GO:0002263	126	0.019
camera type eye development	GO:0043010	266	0.018
regulation of lymphocyte activation	GO:0051249	240	0.018
regulation of cell activation	GO:0050865	289	0.018
protein modification by small protein conjugation	GO:0032446	187	0.017
regulation of t cell activation	GO:0050863	170	0.017
positive regulation of protein modification process	GO:0031401	299	0.017
cytokine production	GO:0001816	319	0.017
muscle tissue development	GO:0060537	308	0.016
organelle assembly	GO:0070925	177	0.016
negative regulation of protein metabolic process	GO:0051248	282	0.016
microtubule cytoskeleton organization	GO:0000226	157	0.016
response to organonitrogen compound	GO:0010243	246	0.015
muscle cell differentiation	GO:0042692	261	0.015
fertilization	GO:0009566	127	0.015
macromolecule catabolic process	GO:0009057	281	0.015
transmembrane transport	GO:0055085	412	0.015
male gamete generation	GO:0048232	285	0.015
lymphocyte mediated immunity	GO:0002449	139	0.015
positive regulation of programmed cell death	GO:0043068	218	0.015
posttranscriptional regulation of gene expression	GO:0010608	155	0.015
protein modification by small protein conjugation or removal	GO:0070647	207	0.015
myeloid cell differentiation	GO:0030099	233	0.015
regulation of membrane potential	GO:0042391	192	0.015
protein ubiquitination	GO:0016567	171	0.015
cellular response to dna damage stimulus	GO:0006974	207	0.014
endocytosis	GO:0006897	168	0.014
nucleobase containing small molecule metabolic process	GO:0055086	352	0.014
regulation of cellular response to stress	GO:0080135	159	0.014
cellular homeostasis	GO:0019725	240	0.014
positive regulation of cell development	GO:0010720	237	0.014
negative regulation of protein modification process	GO:0031400	163	0.014
gene silencing	GO:0016458	38	0.014
multicellular organismal signaling	GO:0035637	91	0.014
positive regulation of cell death	GO:0010942	224	0.014
regulation of cellular component biogenesis	GO:0044087	181	0.013
protein methylation	GO:0006479	81	0.013
spermatid development	GO:0007286	108	0.013
germ cell development	GO:0007281	185	0.013
negative regulation of cellular protein metabolic process	GO:0032269	247	0.013
nuclear division	GO:0000280	158	0.013
regulation of hormone levels	GO:0010817	211	0.013
peptidyl amino acid modification	GO:0018193	336	0.013
negative regulation of lymphocyte activation	GO:0051250	91	0.013
gland development	GO:0048732	330	0.013
regulation of t cell differentiation	GO:0045580	83	0.013
negative regulation of intracellular signal transduction	GO:1902532	167	0.013
intracellular protein transport	GO:0006886	204	0.013
protein localization to nucleus	GO:0034504	121	0.013
reactive oxygen species metabolic process	GO:0072593	84	0.013
regulation of cell cycle	GO:0051726	281	0.013
regulation of mapk cascade	GO:0043408	248	0.013
regulation of secretion	GO:0051046	274	0.013
negative regulation of immune system process	GO:0002683	209	0.013
regulation of transferase activity	GO:0051338	263	0.013
spermatid differentiation	GO:0048515	115	0.013
cytoplasmic transport	GO:0016482	234	0.013
regulation of leukocyte differentiation	GO:1902105	159	0.013
cation transmembrane transport	GO:0098655	266	0.013
cellular nitrogen compound catabolic process	GO:0044270	280	0.013
response to organic cyclic compound	GO:0014070	198	0.013
neuron death	GO:0070997	154	0.013
response to acid chemical	GO:0001101	111	0.013
regulation of secretion by cell	GO:1903530	249	0.013
striated muscle tissue development	GO:0014706	293	0.012
neuronal action potential	GO:0019228	54	0.012
fat cell differentiation	GO:0045444	160	0.012
spermatogenesis	GO:0007283	284	0.012
cellular macromolecule catabolic process	GO:0044265	206	0.012
inflammatory response	GO:0006954	244	0.012
nuclear dna replication	GO:0033260	3	0.012
transmission of nerve impulse	GO:0019226	76	0.012
aromatic compound catabolic process	GO:0019439	286	0.012
positive regulation of nervous system development	GO:0051962	221	0.012
adaptive immune response	GO:0002250	155	0.012
action potential	GO:0001508	78	0.012
dna recombination	GO:0006310	92	0.012
nucleocytoplasmic transport	GO:0006913	139	0.012
blastocyst development	GO:0001824	80	0.012
lipid biosynthetic process	GO:0008610	179	0.012
production of molecular mediator of immune response	GO:0002440	103	0.012
histone lysine methylation	GO:0034968	50	0.012
urogenital system development	GO:0001655	261	0.012
heterocycle catabolic process	GO:0046700	280	0.012
negative regulation of phosphate metabolic process	GO:0045936	184	0.012
mapk cascade	GO:0000165	281	0.012
protein maturation	GO:0051604	176	0.012
regulation of cellular catabolic process	GO:0031329	242	0.012
t cell differentiation	GO:0030217	174	0.012
cellular response to lipid	GO:0071396	145	0.011
endomembrane system organization	GO:0010256	147	0.011
protein alkylation	GO:0008213	81	0.011
skeletal system development	GO:0001501	356	0.011
b cell activation	GO:0042113	161	0.011
negative regulation of growth	GO:0045926	99	0.011
negative regulation of cellular amine metabolic process	GO:0033239	1	0.011
cation transport	GO:0006812	399	0.011
purine containing compound metabolic process	GO:0072521	311	0.011
apoptotic signaling pathway	GO:0097190	306	0.011
renal system development	GO:0072001	225	0.011
negative regulation of cellular component organization	GO:0051129	194	0.011
immunoglobulin production	GO:0002377	73	0.011
nucleotide metabolic process	GO:0009117	332	0.011
respiratory tube development	GO:0030323	167	0.011
negative regulation of phosphorus metabolic process	GO:0010563	184	0.011
cell adhesion	GO:0007155	329	0.011
negative regulation of immune effector process	GO:0002698	55	0.011
mrna metabolic process	GO:0016071	84	0.011
inorganic cation transmembrane transport	GO:0098662	207	0.011
mitotic cell cycle process	GO:1903047	159	0.011
nuclear transport	GO:0051169	139	0.011
negative regulation of cell cycle	GO:0045786	123	0.010
regulation of protein localization	GO:0032880	231	0.010
oxidation reduction process	GO:0055114	342	0.010
stem cell differentiation	GO:0048863	268	0.010
regulation of kinase activity	GO:0043549	249	0.010
regulation of hydrolase activity	GO:0051336	246	0.010
cell growth	GO:0016049	130	0.010
protein secretion	GO:0009306	111	0.010
positive regulation of protein phosphorylation	GO:0001934	242	0.010
b cell mediated immunity	GO:0019724	71	0.010
small gtpase mediated signal transduction	GO:0007264	97	0.010
sensory perception	GO:0007600	245	0.010
protein targeting	GO:0006605	143	0.010
retina development in camera type eye	GO:0060041	119	0.010
respiratory system development	GO:0060541	190	0.010
myosin filament assembly	GO:0031034	2	0.010

Zfp35 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.036
immune system disease	DOID:2914	0.036
disease of cellular proliferation	DOID:14566	0.029
cancer	DOID:162	0.029
organ system cancer	DOID:0050686	0.029
hematopoietic system disease	DOID:74	0.025
nervous system disease	DOID:863	0.018
anemia	DOID:2355	0.017
bone marrow disease	DOID:4961	0.012
musculoskeletal system disease	DOID:17	0.011
aplastic anemia	DOID:12449	0.010

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