IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Acaa1b

acetyl-Coenzyme A acyltransferase 1B

(Aliases: MGC29978)

Entrez: 235674
Ensembl: ENSMUSG00000010651
UniProtKB: Q8VCH0
UniProtKB: Q3UKM0

Process Predictions
Disease Predictions

Acaa1b biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
cellular lipid catabolic process	GO:0044242	52	0.725
monocarboxylic acid catabolic process	GO:0072329	27	0.688
lipid oxidation	GO:0034440	29	0.652
carboxylic acid catabolic process	GO:0046395	51	0.598
oxidation reduction process	GO:0055114	342	0.542
lipid modification	GO:0030258	65	0.494
fatty acid catabolic process	GO:0009062	25	0.488
small molecule catabolic process	GO:0044282	71	0.468
lipid catabolic process	GO:0016042	69	0.446
monocarboxylic acid metabolic process	GO:0032787	191	0.430
cellular lipid metabolic process	GO:0044255	323	0.425
fatty acid oxidation	GO:0019395	28	0.412
organic acid catabolic process	GO:0016054	51	0.297
cofactor metabolic process	GO:0051186	80	0.265
fatty acid metabolic process	GO:0006631	121	0.264
fatty acid beta oxidation	GO:0006635	16	0.162
thioester metabolic process	GO:0035383	19	0.111
lipid biosynthetic process	GO:0008610	179	0.089
acyl coa metabolic process	GO:0006637	19	0.084
cellular amino acid metabolic process	GO:0006520	103	0.083
sulfur compound metabolic process	GO:0006790	100	0.082
coenzyme metabolic process	GO:0006732	52	0.072
organic hydroxy compound metabolic process	GO:1901615	203	0.066
steroid metabolic process	GO:0008202	119	0.056
cellular ketone metabolic process	GO:0042180	84	0.053
carbohydrate metabolic process	GO:0005975	230	0.050
regulation of hormone levels	GO:0010817	211	0.050
alcohol metabolic process	GO:0006066	116	0.047
reactive nitrogen species metabolic process	GO:2001057	0	0.047
regulation of cellular ketone metabolic process	GO:0010565	66	0.046
maintenance of location	GO:0051235	89	0.045
glycerolipid metabolic process	GO:0046486	122	0.044
cation transport	GO:0006812	399	0.044
very long chain fatty acid catabolic process	GO:0042760	2	0.042
response to organic cyclic compound	GO:0014070	198	0.042
small molecule biosynthetic process	GO:0044283	132	0.040
cellular amine metabolic process	GO:0044106	44	0.037
apoptotic signaling pathway	GO:0097190	306	0.037
amine metabolic process	GO:0009308	45	0.036
organic anion transport	GO:0015711	137	0.034
very long chain fatty acid metabolic process	GO:0000038	8	0.034
organonitrogen compound biosynthetic process	GO:1901566	192	0.033
neutral lipid metabolic process	GO:0006638	57	0.033
transmembrane transport	GO:0055085	412	0.033
cellular ion homeostasis	GO:0006873	165	0.032
response to nutrient levels	GO:0031667	109	0.032
organic acid biosynthetic process	GO:0016053	86	0.032
regulation of cellular amino acid metabolic process	GO:0006521	5	0.031
lipid localization	GO:0010876	126	0.030
anion transport	GO:0006820	177	0.030
regulation of lipid metabolic process	GO:0019216	118	0.029
protein oligomerization	GO:0051259	67	0.029
nucleobase containing small molecule metabolic process	GO:0055086	352	0.029
coenzyme catabolic process	GO:0009109	5	0.028
negative regulation of cellular protein metabolic process	GO:0032269	247	0.028
regulation of intracellular transport	GO:0032386	159	0.027
regulation of apoptotic signaling pathway	GO:2001233	197	0.026
spermatogenesis	GO:0007283	284	0.024
response to extracellular stimulus	GO:0009991	127	0.024
regulation of cellular amine metabolic process	GO:0033238	20	0.024
cellular modified amino acid metabolic process	GO:0006575	63	0.024
hormone metabolic process	GO:0042445	86	0.024
ion transmembrane transport	GO:0034220	361	0.024
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.023
response to steroid hormone	GO:0048545	56	0.023
cellular chemical homeostasis	GO:0055082	215	0.023
skeletal system development	GO:0001501	356	0.023
cytokine production	GO:0001816	319	0.023
ketone catabolic process	GO:0042182	3	0.023
organic cyclic compound catabolic process	GO:1901361	295	0.023
male gamete generation	GO:0048232	285	0.023
negative regulation of cellular component organization	GO:0051129	194	0.022
nucleotide metabolic process	GO:0009117	332	0.022
t cell activation	GO:0042110	289	0.021
regulation of defense response	GO:0031347	233	0.021
regulation of lymphocyte activation	GO:0051249	240	0.021
response to organonitrogen compound	GO:0010243	246	0.021
membrane organization	GO:0061024	245	0.021
nucleoside phosphate metabolic process	GO:0006753	338	0.020
peptidyl amino acid modification	GO:0018193	336	0.020
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.020
regulation of organelle organization	GO:0033043	289	0.020
response to molecule of bacterial origin	GO:0002237	143	0.019
regulation of secretion	GO:0051046	274	0.019
nitrogen compound transport	GO:0071705	271	0.018
positive regulation of secretion	GO:0051047	130	0.018
carbohydrate derivative biosynthetic process	GO:1901137	183	0.018
aromatic compound catabolic process	GO:0019439	286	0.018
positive regulation of cell death	GO:0010942	224	0.018
regulation of secretion by cell	GO:1903530	249	0.018
cation transmembrane transport	GO:0098655	266	0.018
skin development	GO:0043588	220	0.017
ribonucleoside catabolic process	GO:0042454	206	0.017
germ cell development	GO:0007281	185	0.017
epidermis development	GO:0008544	187	0.017
cellular homeostasis	GO:0019725	240	0.017
glucose metabolic process	GO:0006006	92	0.017
regulation of cytokine production	GO:0001817	266	0.017
negative regulation of molecular function	GO:0044092	258	0.016
acylglycerol metabolic process	GO:0006639	55	0.016
reactive oxygen species metabolic process	GO:0072593	84	0.016
carboxylic acid biosynthetic process	GO:0046394	86	0.016
organonitrogen compound catabolic process	GO:1901565	264	0.016
response to light stimulus	GO:0009416	135	0.016
positive regulation of cellular amine metabolic process	GO:0033240	5	0.016
mitochondrion organization	GO:0007005	134	0.016
organelle fission	GO:0048285	170	0.016
regulation of cholesterol metabolic process	GO:0090181	14	0.016
negative regulation of cell proliferation	GO:0008285	296	0.016
protein tetramerization	GO:0051262	23	0.016
response to acid chemical	GO:0001101	111	0.016
sterol metabolic process	GO:0016125	58	0.016
macromolecule catabolic process	GO:0009057	281	0.016
monosaccharide metabolic process	GO:0005996	106	0.016
apoptotic mitochondrial changes	GO:0008637	48	0.016
regulation of cell activation	GO:0050865	289	0.015
lateral inhibition	GO:0046331	1	0.015
innate immune response	GO:0045087	157	0.015
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.015
regulation of homeostatic process	GO:0032844	182	0.015
short chain fatty acid catabolic process	GO:0019626	2	0.015
regulation of membrane potential	GO:0042391	192	0.015
multicellular organismal signaling	GO:0035637	91	0.015
protein catabolic process	GO:0030163	221	0.015
ribose phosphate metabolic process	GO:0019693	291	0.015
transmission of nerve impulse	GO:0019226	76	0.014
response to lipopolysaccharide	GO:0032496	128	0.014
hematopoietic progenitor cell differentiation	GO:0002244	143	0.014
rhythmic process	GO:0048511	174	0.014
metal ion homeostasis	GO:0055065	189	0.014
cholesterol metabolic process	GO:0008203	56	0.014
cellular response to organonitrogen compound	GO:0071417	145	0.014
negative regulation of cellular amine metabolic process	GO:0033239	1	0.014
organic hydroxy compound biosynthetic process	GO:1901617	77	0.014
regulation of lipid biosynthetic process	GO:0046890	54	0.014
organophosphate biosynthetic process	GO:0090407	122	0.014
cellular metal ion homeostasis	GO:0006875	151	0.014
gland development	GO:0048732	330	0.014
amide transport	GO:0042886	138	0.014
organic acid transport	GO:0015849	101	0.014
epithelial cell development	GO:0002064	159	0.014
regulation of cell cycle	GO:0051726	281	0.014
fatty acyl coa metabolic process	GO:0035337	4	0.014
purine containing compound metabolic process	GO:0072521	311	0.014
nucleoside metabolic process	GO:0009116	246	0.014
cation homeostasis	GO:0055080	212	0.014
homeostasis of number of cells	GO:0048872	210	0.014
positive regulation of apoptotic process	GO:0043065	217	0.014
cellular nitrogen compound catabolic process	GO:0044270	280	0.014
inorganic ion transmembrane transport	GO:0098660	234	0.013
hexose metabolic process	GO:0019318	98	0.013
meiotic cell cycle	GO:0051321	122	0.013
nuclear division	GO:0000280	158	0.013
acetyl coa metabolic process	GO:0006084	8	0.013
inflammatory response	GO:0006954	244	0.013
cellular glucan metabolic process	GO:0006073	32	0.013
neuronal action potential	GO:0019228	54	0.013
plasma membrane organization	GO:0007009	90	0.013
positive regulation of cell activation	GO:0050867	158	0.013
striated muscle tissue development	GO:0014706	293	0.013
defense response to bacterium	GO:0042742	119	0.013
response to insulin	GO:0032868	100	0.013
camera type eye development	GO:0043010	266	0.013
carbohydrate homeostasis	GO:0033500	128	0.013
protein maturation	GO:0051604	176	0.013
positive regulation of lymphocyte activation	GO:0051251	140	0.013
positive regulation of protein modification process	GO:0031401	299	0.013
meiotic nuclear division	GO:0007126	115	0.013
endocytosis	GO:0006897	168	0.013
protein processing	GO:0016485	163	0.013
regulation of t cell activation	GO:0050863	170	0.013
positive regulation of programmed cell death	GO:0043068	218	0.012
endomembrane system organization	GO:0010256	147	0.012
divalent inorganic cation homeostasis	GO:0072507	138	0.012
cellular response to lipid	GO:0071396	145	0.012
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.012
carboxylic acid transport	GO:0046942	100	0.012
positive regulation of secretion by cell	GO:1903532	114	0.012
chemotaxis	GO:0006935	247	0.012
negative regulation of protein metabolic process	GO:0051248	282	0.012
isoprenoid metabolic process	GO:0006720	29	0.012
lymphocyte mediated immunity	GO:0002449	139	0.012
multicellular organismal homeostasis	GO:0048871	164	0.012
defense response to other organism	GO:0098542	197	0.012
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.012
alpha amino acid metabolic process	GO:1901605	59	0.012
chromatin organization	GO:0006325	206	0.012
glucose homeostasis	GO:0042593	128	0.012
purine nucleotide metabolic process	GO:0006163	302	0.012
regulation of cellular response to stress	GO:0080135	159	0.012
lipid storage	GO:0019915	36	0.012
coenzyme a metabolic process	GO:0015936	8	0.012
tissue homeostasis	GO:0001894	115	0.012
cell type specific apoptotic process	GO:0097285	268	0.012
cytoplasmic transport	GO:0016482	234	0.011
anatomical structure homeostasis	GO:0060249	145	0.011
retinoid metabolic process	GO:0001523	24	0.011
glutathione metabolic process	GO:0006749	16	0.011
ubiquitin dependent protein catabolic process	GO:0006511	129	0.011
cellular response to hormone stimulus	GO:0032870	150	0.011
gonad development	GO:0008406	141	0.011
regulation of hydrolase activity	GO:0051336	246	0.011
purine ribonucleotide metabolic process	GO:0009150	290	0.011
bone development	GO:0060348	120	0.011
synaptic transmission	GO:0007268	329	0.011
t cell differentiation	GO:0030217	174	0.011
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.011
forebrain development	GO:0030900	302	0.011
dna metabolic process	GO:0006259	303	0.011
fatty acid alpha oxidation	GO:0001561	2	0.011
actin cytoskeleton organization	GO:0030036	220	0.011
response to epidermal growth factor	GO:0070849	4	0.011
cellular protein complex assembly	GO:0043623	116	0.011
multicellular organism growth	GO:0035264	161	0.011
negative regulation of intracellular signal transduction	GO:1902532	167	0.011
cellular calcium ion homeostasis	GO:0006874	119	0.011
positive regulation of protein phosphorylation	GO:0001934	242	0.011
leukocyte migration	GO:0050900	124	0.011
cellular response to acid chemical	GO:0071229	68	0.011
smoothened signaling pathway	GO:0007224	105	0.011
protein modification by small protein conjugation	GO:0032446	187	0.011
negative regulation of lipid metabolic process	GO:0045833	30	0.011
placenta development	GO:0001890	140	0.011
cell adhesion	GO:0007155	329	0.011
chromatin modification	GO:0016568	187	0.011
negative regulation of proteolysis	GO:0045861	74	0.011
regulation of protein complex assembly	GO:0043254	83	0.011
nucleotide biosynthetic process	GO:0009165	78	0.011
organophosphate catabolic process	GO:0046434	232	0.011
sequestering of metal ion	GO:0051238	19	0.011
covalent chromatin modification	GO:0016569	163	0.010
leukocyte activation involved in immune response	GO:0002366	126	0.010
heterocycle catabolic process	GO:0046700	280	0.010
response to peptide	GO:1901652	136	0.010
regulation of kinase activity	GO:0043549	249	0.010
response to radiation	GO:0009314	165	0.010
g protein coupled receptor signaling pathway	GO:0007186	243	0.010
nucleotide catabolic process	GO:0009166	217	0.010
fat soluble vitamin biosynthetic process	GO:0042362	4	0.010
negative regulation of phosphorylation	GO:0042326	166	0.010
peptide secretion	GO:0002790	114	0.010
microtubule based process	GO:0007017	236	0.010
response to inorganic substance	GO:0010035	96	0.010
carbohydrate derivative catabolic process	GO:1901136	231	0.010
negative regulation of protein modification process	GO:0031400	163	0.010
peptidyl tyrosine modification	GO:0018212	145	0.010
cellular response to cytokine stimulus	GO:0071345	189	0.010
regulation of vesicle mediated transport	GO:0060627	139	0.010
protein homooligomerization	GO:0051260	43	0.010
protein localization to organelle	GO:0033365	185	0.010
leukocyte proliferation	GO:0070661	172	0.010

Acaa1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.022
nervous system disease	DOID:863	0.022
inherited metabolic disorder	DOID:655	0.021
disease of metabolism	DOID:0014667	0.021
central nervous system disease	DOID:331	0.015
brain disease	DOID:936	0.013

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