Mus musculus

0 known processes

Lefty2

left-right determination factor 2

(Aliases: MGC98569,AV214969,Ebaf,6030463A22Rik,Lefta,Leftb)

Lefty2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nodal signaling pathwayGO:0038092100.302
Mouse
forebrain developmentGO:00309003020.136
Zebrafish
regionalizationGO:00030023370.098
Zebrafish Mouse
transmembrane transportGO:00550854120.095
mesendoderm developmentGO:004838230.094
heart morphogenesisGO:00030071780.086
Zebrafish Mouse
ion transmembrane transportGO:00342203610.085
regulation of cellular ketone metabolic processGO:0010565660.078
regulation of cell adhesionGO:00301551540.077
respiratory system developmentGO:00605411900.076
muscle tissue developmentGO:00605373080.075
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.073
Mouse
cellular lipid metabolic processGO:00442553230.070
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.068
Mouse
response to retinoic acidGO:0032526560.067
Mouse
kidney developmentGO:00018222130.067
negative regulation of nodal signaling pathwayGO:190010830.065
Mouse
determination of heart left right asymmetryGO:0061371480.063
Zebrafish
anion transportGO:00068201770.063
regulation of nodal signaling pathwayGO:190010740.062
Mouse
negative regulation of cellular component organizationGO:00511291940.061
Mouse
cell migration involved in gastrulationGO:0042074130.060
Mouse
mesoderm developmentGO:00074981000.059
Zebrafish
organic anion transportGO:00157111370.055
digestive tract morphogenesisGO:00485461470.054
Mouse
amine metabolic processGO:0009308450.053
regulation of activin receptor signaling pathwayGO:0032925100.052
Mouse
cardiac chamber morphogenesisGO:0003206930.051
hematopoietic progenitor cell differentiationGO:00022441430.051
cellular amine metabolic processGO:0044106440.051
cellular amino acid metabolic processGO:00065201030.050
response to growth factorGO:00708481980.048
response to transforming growth factor betaGO:0071559880.046
regulation of membrane potentialGO:00423911920.046
regulation of system processGO:00440572000.045
cation transmembrane transportGO:00986552660.045
cellular ketone metabolic processGO:0042180840.044
regulation of receptor activityGO:0010469410.044
camera type eye developmentGO:00430102660.044
wnt signaling pathwayGO:00160551880.043
axial mesodermal cell fate commitmentGO:004832210.043
developmental maturationGO:00217001930.043
epithelial cell developmentGO:00020641590.042
regulation of cellular component biogenesisGO:00440871810.041
Mouse
spemann organizer formationGO:006006120.041
maintenance of locationGO:0051235890.041
regulation of cellular amine metabolic processGO:0033238200.040
urogenital system developmentGO:00016552610.039
prechordal plate formationGO:002150110.039
epithelial tube morphogenesisGO:00605623030.038
telencephalon developmentGO:00215371860.038
regulation of neuron apoptotic processGO:00435231220.037
negative regulation of activin receptor signaling pathwayGO:003292660.036
Mouse
lung developmentGO:00303241640.036
innate immune responseGO:00450871570.036
gastrulationGO:00073691160.035
Mouse
renal system developmentGO:00720012250.035
cardiac muscle tissue developmentGO:00487381300.035
nitrogen compound transportGO:00717052710.035
negative regulation of cell proliferationGO:00082852960.035
Mouse
cellular response to transforming growth factor beta stimulusGO:0071560880.034
locomotory behaviorGO:00076261950.034
canonical wnt signaling pathwayGO:00600701300.034
cation homeostasisGO:00550802120.033
cell maturationGO:00484691270.033
neuronal action potentialGO:0019228540.033
transforming growth factor beta receptor signaling pathwayGO:0007179710.033
negative regulation of nervous system developmentGO:00519611560.033
axial mesodermal cell fate specificationGO:004832710.033
amino acid transportGO:0006865610.032
cell matrix adhesionGO:0007160680.032
posttranscriptional regulation of gene expressionGO:00106081550.032
inorganic cation transmembrane transportGO:00986622070.032
skeletal system morphogenesisGO:00487052030.031
central nervous system neuron differentiationGO:00219531620.031
axial mesoderm formationGO:004832030.031
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.031
Mouse
response to acid chemicalGO:00011011110.031
Mouse
regulation of secretion by cellGO:19035302490.030
cell growthGO:00160491300.030
regulation of cell motilityGO:20001452360.030
cation transportGO:00068123990.029
fertilizationGO:00095661270.029
carboxylic acid transportGO:00469421000.028
oocyte constructionGO:000730820.028
extracellular structure organizationGO:00430621480.027
regulation of lipid metabolic processGO:00192161180.027
embryonic heart tube developmentGO:0035050650.027
Zebrafish
action potentialGO:0001508780.027
regulation of neuron differentiationGO:00456642810.026
ureteric bud morphogenesisGO:0060675620.026
organic acid transportGO:00158491010.026
cell type specific apoptotic processGO:00972852680.026
blood vessel morphogenesisGO:00485142850.026
embryonic skeletal system developmentGO:00487061200.026
skin developmentGO:00435882200.026
negative regulation of molecular functionGO:00440922580.026
determination of left right symmetryGO:0007368800.026
Zebrafish Mouse
neural tube developmentGO:00219151600.026
associative learningGO:0008306610.026
ameboidal type cell migrationGO:00016671280.025
Mouse
sensory perception of soundGO:0007605970.025
regulation of androgen receptor signaling pathwayGO:006076530.025
skeletal system developmentGO:00015013560.025
microtubule based processGO:00070172360.024
learning or memoryGO:00076111480.024
cardiac muscle cell differentiationGO:0055007690.024
limb developmentGO:00601731660.024
cellular response to lipidGO:00713961450.024
negative regulation of wnt signaling pathwayGO:0030178730.023
regulation of protein localizationGO:00328802310.023
amino acid transmembrane transportGO:0003333370.023
negative regulation of cell developmentGO:00107211690.023
gland developmentGO:00487323300.022
cardiac chamber developmentGO:00032051080.022
methionine transportGO:001582110.022
cardiocyte differentiationGO:0035051870.022
regulation of organelle organizationGO:00330432890.022
cellular response to cytokine stimulusGO:00713451890.022
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.022
oocyte axis specificationGO:000730920.021
notochord developmentGO:0030903200.021
endocardial cell differentiationGO:006095640.021
cellular response to growth factor stimulusGO:00713631970.021
anion transmembrane transportGO:0098656710.021
asymmetric stem cell divisionGO:009872230.021
single organism cell adhesionGO:00986021560.021
multicellular organismal signalingGO:0035637910.021
positive regulation of nervous system developmentGO:00519622210.021
regulation of translationGO:0006417710.021
embryonic placenta developmentGO:0001892980.021
muscle system processGO:00030121410.021
regulation of cell cycle processGO:00105641600.021
regulation of cell cycleGO:00517262810.020
branching morphogenesis of an epithelial tubeGO:00487541590.020
carbohydrate homeostasisGO:00335001280.020
organ growthGO:00352651170.020
epidermis developmentGO:00085441870.020
male sex differentiationGO:00466611090.020
morphogenesis of a branching structureGO:00017632030.020
digestive system developmentGO:00551232000.020
Mouse
cognitionGO:00508901490.020
dna metabolic processGO:00062593030.020
stem cell fate specificationGO:004886630.019
protein ubiquitinationGO:00165671710.019
protein modification by small protein conjugationGO:00324461870.019
left lung developmentGO:006045940.019
positive regulation of protein modification processGO:00314012990.019
monocarboxylic acid metabolic processGO:00327871910.019
fatty acid metabolic processGO:00066311210.019
nephron tubule morphogenesisGO:0072078680.019
response to light stimulusGO:00094161350.019
male gamete generationGO:00482322850.019
ribonucleotide metabolic processGO:00092592910.019
septum primum developmentGO:000328440.019
cell substrate adhesionGO:00315891300.019
cardiac septum developmentGO:0003279590.019
cellular chemical homeostasisGO:00550822150.019
regulation of ossificationGO:00302781120.018
regulation of organ morphogenesisGO:20000271440.018
organic hydroxy compound metabolic processGO:19016152030.018
stem cell maintenanceGO:00198271300.018
hair follicle developmentGO:0001942850.018
inorganic ion transmembrane transportGO:00986602340.018
lateral ventricle developmentGO:0021670110.018
glucose homeostasisGO:00425931280.018
heart formationGO:0060914160.018
Zebrafish
sulfur compound metabolic processGO:00067901000.018
protein maturationGO:00516041760.018
ras protein signal transductionGO:0007265770.018
carbohydrate metabolic processGO:00059752300.018
negative regulation of phosphate metabolic processGO:00459361840.018
oxidation reduction processGO:00551143420.018
embryonic organ morphogenesisGO:00485622760.018
blastocyst developmentGO:0001824800.018
reactive oxygen species metabolic processGO:0072593840.018
reactive nitrogen species metabolic processGO:200105700.017
circulatory system processGO:00030131970.017
specification of organ identityGO:0010092300.017
Zebrafish
ear morphogenesisGO:00424711180.017
synapse organizationGO:00508081250.017
sensory perceptionGO:00076002450.017
exocytosisGO:00068871210.017
muscle cell differentiationGO:00426922610.017
nuclear divisionGO:00002801580.017
positive regulation of cell substrate adhesionGO:0010811470.017
heart processGO:0003015940.017
somitogenesisGO:0001756690.017
protein localization to membraneGO:00726571080.017
gliogenesisGO:00420631410.017
regulation of cell activationGO:00508652890.017
negative regulation of cellular response to growth factor stimulusGO:0090288460.017
purine containing compound metabolic processGO:00725213110.017
regulation of ion transportGO:00432692150.017
ribonucleoside metabolic processGO:00091192450.016
stem cell developmentGO:00488642190.016
nucleoside triphosphate metabolic processGO:00091412300.016
response to inorganic substanceGO:0010035960.016
potassium ion homeostasisGO:005507540.016
sensory organ morphogenesisGO:00905962420.016
av node cell to bundle of his cell communicationGO:008606720.016
cardiac ventricle developmentGO:0003231830.016
negative regulation of phosphorus metabolic processGO:00105631840.016
positive regulation of cellular amine metabolic processGO:003324050.016
synaptic transmissionGO:00072683290.016
regulation of transmembrane transportGO:00347621280.016
regulation of mapk cascadeGO:00434082480.016
developmental growth involved in morphogenesisGO:00605601380.016
regulation of muscle system processGO:0090257800.016
pole plasm assemblyGO:000731520.016
mesonephric tubule morphogenesisGO:0072171630.016
segmentationGO:0035282930.016
spermatogenesisGO:00072832840.016
regulation of secretionGO:00510462740.016
metanephric loop of henle developmentGO:007223640.016
response to extracellular stimulusGO:00099911270.015
nucleobase containing small molecule metabolic processGO:00550863520.015
translationGO:0006412930.015
lipid localizationGO:00108761260.015
ventral midline developmentGO:000741840.015
negative regulation of neuron deathGO:1901215980.015
regulation of cell substrate adhesionGO:0010810730.015
organic hydroxy compound transportGO:0015850930.015
ribose phosphate metabolic processGO:00196932910.015
rho protein signal transductionGO:0007266320.015
small gtpase mediated signal transductionGO:0007264970.015
germ cell developmentGO:00072811850.015
regulation of muscle contractionGO:0006937490.015
adult behaviorGO:00305341350.015
single organismal cell cell adhesionGO:00163371310.015
regulation of cell projection organizationGO:00313442060.015
retina development in camera type eyeGO:00600411190.015
protein oligomerizationGO:0051259670.015
positive regulation of cell motilityGO:20001471160.015
learningGO:0007612980.015
transmission of nerve impulseGO:0019226760.015
thermosensory behaviorGO:004004010.015
striated muscle tissue developmentGO:00147062930.015
actin filament organizationGO:00070151130.015
spinal cord developmentGO:0021510810.015
cellular protein complex assemblyGO:00436231160.015
Mouse
neuromuscular processGO:0050905990.015
response to organonitrogen compoundGO:00102432460.015
response to peptideGO:19016521360.015
actin cytoskeleton organizationGO:00300362200.015
cell fate commitmentGO:00451652100.015
insulin secretionGO:0030073890.014
purine nucleotide metabolic processGO:00061633020.014
regulation of synaptic plasticityGO:0048167870.014
mitochondrion organizationGO:00070051340.014
endoderm developmentGO:0007492450.014
regulation of apoptotic signaling pathwayGO:20012331970.014
left right pattern formationGO:0060972230.014
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512260.014
cellular homeostasisGO:00197252400.014
hormone metabolic processGO:0042445860.014
purine nucleoside metabolic processGO:00422782410.014
glial cell differentiationGO:00100011310.014
homeostasis of number of cellsGO:00488722100.014
neurohypophysis developmentGO:002198520.014
heart contractionGO:0060047930.014
floor plate morphogenesisGO:003350530.014
artery developmentGO:0060840530.014
regulation of cellular amino acid metabolic processGO:000652150.014
regulation of cell divisionGO:0051302760.014
actin mediated cell contractionGO:0070252150.014
response to monosaccharideGO:0034284670.014
regulation of neuron projection developmentGO:00109751690.014
organelle fissionGO:00482851700.014
stem cell differentiationGO:00488632680.013
regulation of response to woundingGO:19030341890.013
negative regulation of glial cell proliferationGO:006025340.013
ossificationGO:00015032160.013
ribonucleoside catabolic processGO:00424542060.013
metal ion homeostasisGO:00550651890.013
nucleoside phosphate metabolic processGO:00067533380.013
apoptotic signaling pathwayGO:00971903060.013
organonitrogen compound biosynthetic processGO:19015661920.013
positive regulation of cell developmentGO:00107202370.013
metanephros developmentGO:0001656790.013
inflammatory responseGO:00069542440.013
intracellular protein transportGO:00068862040.013
protein secretionGO:00093061110.013
lipid biosynthetic processGO:00086101790.013
cell fate specificationGO:0001708720.013
organonitrogen compound catabolic processGO:19015652640.013
myeloid cell differentiationGO:00300992330.013
sodium ion transportGO:0006814730.013
endomembrane system organizationGO:00102561470.013
purine ribonucleotide catabolic processGO:00091542080.013
satellite cell activation involved in skeletal muscle regenerationGO:001490130.013
columnar cuboidal epithelial cell differentiationGO:0002065820.013
protein modification by small protein conjugation or removalGO:00706472070.013
intracellular mrna localizationGO:000829840.013
oocyte anterior posterior axis specificationGO:000731420.013
purine ribonucleotide metabolic processGO:00091502900.013
circadian rhythmGO:00076231140.013
nucleotide metabolic processGO:00091173320.013
positive regulation of dna endoreduplicationGO:003287720.013
cellular response to organonitrogen compoundGO:00714171450.013
regulation of blood circulationGO:1903522930.013
purine ribonucleoside catabolic processGO:00461302050.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.013
cell junction organizationGO:0034330770.013
response to organic cyclic compoundGO:00140701980.013
positive regulation of cellular amino acid metabolic processGO:004576430.013
membrane organizationGO:00610242450.013
response to radiationGO:00093141650.013
odontogenesis of dentin containing toothGO:0042475660.012
olfactory learningGO:000835520.012
peptidyl amino acid modificationGO:00181933360.012
calcium ion homeostasisGO:00550741270.012
neural tube patterningGO:0021532430.012
regulation of establishment of protein localizationGO:00702011810.012
immune effector processGO:00022523210.012
ribonucleoside triphosphate metabolic processGO:00091992200.012
sensory perception of mechanical stimulusGO:00509541070.012
cardiac septum morphogenesisGO:0060411460.012
regulation of synaptic transmission glutamatergicGO:0051966190.012
activin receptor signaling pathwayGO:0032924180.012
Mouse
aromatic compound catabolic processGO:00194392860.012
liver developmentGO:0001889660.012
transition metal ion homeostasisGO:0055076540.012
neuron deathGO:00709971540.012
regulation of anatomical structure sizeGO:00900661780.012
regulation of cellular component sizeGO:00325351210.012
lens development in camera type eyeGO:0002088620.012
negative regulation of neuron apoptotic processGO:0043524920.012
nucleoside monophosphate metabolic processGO:0009123850.012
cell adhesionGO:00071553290.012
regulation of ion transmembrane transportGO:00347651190.012
neutral lipid metabolic processGO:0006638570.012
cytokine productionGO:00018163190.012
cellular response to organic cyclic compoundGO:0071407870.012
rhythmic processGO:00485111740.012
endodermal cell fate specificationGO:000171440.012
axonogenesisGO:00074092740.012
negative regulation of cellular amine metabolic processGO:003323910.012
meiotic nuclear divisionGO:00071261150.012
renal system processGO:0003014480.012
negative regulation of cellular amino acid metabolic processGO:004576300.012
nephron epithelium developmentGO:0072009920.012
male gonad developmentGO:0008584880.012
cholesterol metabolic processGO:0008203560.012
negative regulation of phosphorylationGO:00423261660.012
carbohydrate derivative catabolic processGO:19011362310.012
divalent inorganic cation transportGO:00725111780.012
cellular nitrogen compound catabolic processGO:00442702800.012
myeloid leukocyte differentiationGO:00025731190.012
positive regulation of hydrolase activityGO:00513451480.012
protein localization to nucleusGO:00345041210.011
negative regulation of cellular protein metabolic processGO:00322692470.011
nucleoside phosphate catabolic processGO:19012922220.011
embryonic heart tube morphogenesisGO:0003143510.011
amide transportGO:00428861380.011
cellular response to hormone stimulusGO:00328701500.011
gonad developmentGO:00084061410.011
mesonephric tubule developmentGO:0072164940.011
nucleoside triphosphate catabolic processGO:00091432050.011
blood circulationGO:00080151950.011
phospholipid metabolic processGO:0006644870.011
leukocyte differentiationGO:00025213420.011
astrocyte fate commitmentGO:006001840.011
sodium ion transmembrane transportGO:0035725490.011
regulation of satellite cell activation involved in skeletal muscle regenerationGO:001471730.011
cellular response to acid chemicalGO:0071229680.011
metanephros morphogenesisGO:0003338240.011
monosaccharide metabolic processGO:00059961060.011
regulation of homeostatic processGO:00328441820.011
sterol metabolic processGO:0016125580.011
maternal determination of anterior posterior axis embryoGO:000835820.011
lateral inhibitionGO:004633110.011
nephron developmentGO:00720061090.011
meiotic cell cycleGO:00513211220.011
pharynx developmentGO:006046510.011
single fertilizationGO:0007338820.011
mesonephric epithelium developmentGO:0072163940.011
generation of precursor metabolites and energyGO:00060911030.011
regulation of interleukin 8 secretionGO:200048220.011
macromolecule methylationGO:00434141200.011
regulation of synapse structural plasticityGO:005182340.011
germ line stem cell divisionGO:004207820.011
regulation of actin filament based processGO:0032970990.011
sertoli cell differentiationGO:0060008180.011
metanephric epithelium developmentGO:0072207210.011
g protein coupled receptor signaling pathwayGO:00071862430.011
long term synaptic potentiationGO:0060291250.011
mesenchyme developmentGO:00604851520.011
Zebrafish
regulation of defense responseGO:00313472330.011
neuroblast differentiationGO:001401620.011
regulation of fibroblast proliferationGO:0048145340.011
multicellular organismal homeostasisGO:00488711640.011
t cell activationGO:00421102890.011
negative regulation of nik nf kappab signalingGO:190122320.011
regulation of hippo signalingGO:003533010.011
cellular response to extracellular stimulusGO:0031668810.011
cardiac muscle cell contractionGO:008600370.011
specification of organ positionGO:001015930.011
energy derivation by oxidation of organic compoundsGO:0015980770.011
sa node cell action potentialGO:008601540.011
peptidyl serine phosphorylationGO:0018105740.011
fibroblast proliferationGO:0048144350.011
myelinationGO:0042552740.011
cellular response to peptide hormone stimulusGO:0071375920.011
sclerotome developmentGO:006105640.011
regulation of gtp catabolic processGO:00331241130.011
negative regulation of intracellular signal transductionGO:19025321670.011
respiratory tube developmentGO:00303231670.011
negative regulation of stem cell maintenanceGO:190245540.010
primary neural tube formationGO:0014020950.010
prostate gland morphogenetic growthGO:006073740.010
striated muscle contractionGO:0006941450.010
protein processingGO:00164851630.010
developmental cell growthGO:0048588840.010
peptide hormone secretionGO:00300721090.010
regulation of vesicle mediated transportGO:00606271390.010
protein localization to organelleGO:00333651850.010
midgut developmentGO:000749440.010
meiosis iGO:0007127600.010
appendage developmentGO:00487361660.010
angiogenesisGO:00015252010.010
regulation of wnt signaling pathwayGO:00301111230.010
mesodermal cell migrationGO:000807840.010
thyroid stimulating hormone secreting cell differentiationGO:006012940.010
cardiac muscle contractionGO:0060048320.010
regulation of reactive oxygen species metabolic processGO:2000377400.010
cellular carbohydrate metabolic processGO:00442621190.010
positive regulation of interleukin 8 secretionGO:200048410.010
cell divisionGO:00513011200.010
regulation of heart contractionGO:0008016770.010
regulation of bmp signaling pathwayGO:0030510600.010
axial mesoderm developmentGO:004831880.010
steroid metabolic processGO:00082021190.010
cellular response to starvationGO:0009267570.010
endoderm formationGO:0001706200.010
regulation of proteolysisGO:00301621640.010
rna interferenceGO:001624620.010
regulation of renin secretion into blood streamGO:190013340.010
regulation of body fluid levelsGO:00508781620.010
muscle contractionGO:00069361010.010

Lefty2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.014
cardiovascular system diseaseDOID:128700.014
nervous system diseaseDOID:86300.011