Mus musculus

19 known processes

Akt1s1

AKT1 substrate 1 (proline-rich)

(Aliases: Lobe,AI227026,PRAS40,Lobel,1110012J22Rik)

Akt1s1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organic acid transportGO:00158491010.162
cellular amino acid metabolic processGO:00065201030.153
organic anion transportGO:00157111370.136
regulation of cellular catabolic processGO:00313292420.133
anion transportGO:00068201770.108
carboxylic acid transportGO:00469421000.081
intracellular protein transportGO:00068862040.076
regulation of cell motilityGO:20001452360.066
multi multicellular organism processGO:00447061090.065
multicellular organism growthGO:00352641610.064
forebrain developmentGO:00309003020.064
spermatogenesisGO:00072832840.062
skeletal system developmentGO:00015013560.062
cytoplasmic transportGO:00164822340.061
regulation of cellular ketone metabolic processGO:0010565660.059
sensory organ morphogenesisGO:00905962420.058
proteolysis involved in cellular protein catabolic processGO:00516031470.056
connective tissue developmentGO:00614481790.054
carbohydrate derivative biosynthetic processGO:19011371830.051
protein targetingGO:00066051430.049
endomembrane system organizationGO:00102561470.049
oxidation reduction processGO:00551143420.048
nitrogen compound transportGO:00717052710.048
regulation of cellular amine metabolic processGO:0033238200.048
ras protein signal transductionGO:0007265770.046
modification dependent protein catabolic processGO:00199411330.045
protein localization to membraneGO:00726571080.044
ubiquitin dependent protein catabolic processGO:00065111290.043
cellular response to lipidGO:00713961450.043
proteasomal protein catabolic processGO:0010498980.043
cartilage developmentGO:00512161400.043
regulation of cell migrationGO:00303342190.042
cellular protein catabolic processGO:00442571550.042
eye photoreceptor cell developmentGO:0042462310.042
negative regulation of cellular protein metabolic processGO:00322692470.041
response to organonitrogen compoundGO:00102432460.041
male gamete generationGO:00482322850.041
camera type eye developmentGO:00430102660.040
regulation of cell adhesionGO:00301551540.040
protein glycosylationGO:0006486550.040
mitochondrion organizationGO:00070051340.039
modification dependent macromolecule catabolic processGO:00436321330.039
germ cell developmentGO:00072811850.039
carbohydrate metabolic processGO:00059752300.037
transmembrane transportGO:00550854120.037
cellular ketone metabolic processGO:0042180840.036
macromolecule glycosylationGO:0043413550.036
protein localization to organelleGO:00333651850.035
cation transportGO:00068123990.035
appendage developmentGO:00487361660.034
neuron migrationGO:00017641220.034
regulation of cellular amino acid metabolic processGO:000652150.034
macromolecule catabolic processGO:00090572810.034
positive regulation of cellular amine metabolic processGO:003324050.034
muscle system processGO:00030121410.034
monocarboxylic acid metabolic processGO:00327871910.033
small gtpase mediated signal transductionGO:0007264970.033
regulation of protein catabolic processGO:00421761080.033
organophosphate catabolic processGO:00464342320.033
regulation of purine nucleotide metabolic processGO:19005421690.033
circulatory system processGO:00030131970.033
regulation of proteolysisGO:00301621640.032
organonitrogen compound biosynthetic processGO:19015661920.032
neuron neuron synaptic transmissionGO:0007270690.032
protein modification by small protein conjugationGO:00324461870.031
positive regulation of nucleotide metabolic processGO:00459811140.031
acid secretionGO:0046717330.031
nucleotide metabolic processGO:00091173320.031
cellular lipid metabolic processGO:00442553230.031
regulation of embryonic developmentGO:0045995710.030
positive regulation of cell developmentGO:00107202370.030
cellular amine metabolic processGO:0044106440.030
purine nucleoside metabolic processGO:00422782410.030
positive regulation of purine nucleotide metabolic processGO:19005441140.030
gland developmentGO:00487323300.030
vesicle localizationGO:0051648860.030
negative regulation of phosphate metabolic processGO:00459361840.029
monocarboxylic acid transportGO:0015718440.029
developmental growth involved in morphogenesisGO:00605601380.029
respiratory tube developmentGO:00303231670.029
limb developmentGO:00601731660.028
blood vessel morphogenesisGO:00485142850.028
dna metabolic processGO:00062593030.028
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.028
protein maturationGO:00516041760.028
microtubule based processGO:00070172360.028
cell maturationGO:00484691270.028
glycerolipid metabolic processGO:00464861220.028
myeloid cell differentiationGO:00300992330.027
regulation of cellular component biogenesisGO:00440871810.027
regulation of body fluid levelsGO:00508781620.027
regulation of hormone levelsGO:00108172110.027
regulation of system processGO:00440572000.027
regulation of lipid metabolic processGO:00192161180.026
embryonic organ morphogenesisGO:00485622760.026
female gamete generationGO:0007292740.026
regulation of secretionGO:00510462740.026
response to organic cyclic compoundGO:00140701980.026
regulation of protein transportGO:00512231630.026
purine containing compound metabolic processGO:00725213110.026
negative regulation of protein phosphorylationGO:00019331260.026
positive regulation of secretionGO:00510471300.026
photoreceptor cell differentiationGO:0046530520.026
regulation of establishment of protein localizationGO:00702011810.026
protein modification by small protein conjugation or removalGO:00706472070.026
leukocyte differentiationGO:00025213420.026
protein catabolic processGO:00301632210.025
regulation of nucleotide metabolic processGO:00061401690.025
bone developmentGO:00603481200.025
glucose homeostasisGO:00425931280.025
muscle contractionGO:00069361010.025
establishment of protein localization to organelleGO:00725941180.025
ion transmembrane transportGO:00342203610.025
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.025
skeletal system morphogenesisGO:00487052030.024
regulation of membrane potentialGO:00423911920.024
synaptic transmissionGO:00072683290.024
epithelial cell proliferationGO:00506731740.024
regulation of cellular protein catabolic processGO:1903362610.024
organonitrogen compound catabolic processGO:19015652640.024
ribose phosphate metabolic processGO:00196932910.024
anion transmembrane transportGO:0098656710.024
skin developmentGO:00435882200.024
mapk cascadeGO:00001652810.024
organophosphate biosynthetic processGO:00904071220.024
response to radiationGO:00093141650.024
small molecule catabolic processGO:0044282710.023
limb morphogenesisGO:00351081490.023
amide transportGO:00428861380.023
regulation of map kinase activityGO:00434051200.023
actin filament organizationGO:00070151130.023
negative regulation of protein modification processGO:00314001630.023
glycosyl compound metabolic processGO:19016572460.023
ossificationGO:00015032160.023
organic acid catabolic processGO:0016054510.023
developmental maturationGO:00217001930.022
rho protein signal transductionGO:0007266320.022
nucleobase containing small molecule metabolic processGO:00550863520.022
purine ribonucleotide metabolic processGO:00091502900.022
cell substrate adhesionGO:00315891300.022
carbohydrate derivative catabolic processGO:19011362310.022
amine metabolic processGO:0009308450.022
aromatic compound catabolic processGO:00194392860.021
cellular response to hormone stimulusGO:00328701500.021
single organism cell adhesionGO:00986021560.021
embryonic appendage morphogenesisGO:00351131260.021
nucleoside phosphate metabolic processGO:00067533380.021
amino acid transportGO:0006865610.021
blood circulationGO:00080151950.021
positive regulation of cellular amino acid metabolic processGO:004576430.021
regulation of protein localizationGO:00328802310.021
negative regulation of protein metabolic processGO:00512482820.021
regulation of actin filament based processGO:0032970990.021
embryonic placenta developmentGO:0001892980.021
ribonucleotide catabolic processGO:00092612080.021
actin cytoskeleton organizationGO:00300362200.021
spermatid differentiationGO:00485151150.020
regulation of epithelial cell proliferationGO:00506781410.020
placenta developmentGO:00018901400.020
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.020
glycoprotein metabolic processGO:00091001160.020
purine nucleoside triphosphate metabolic processGO:00091442260.020
regulation of protein serine threonine kinase activityGO:00719001570.020
cell adhesionGO:00071553290.020
cellular nitrogen compound catabolic processGO:00442702800.019
metal ion homeostasisGO:00550651890.019
compound eye developmentGO:004874910.019
purine ribonucleoside triphosphate metabolic processGO:00092052200.019
glycosylationGO:0070085620.019
leukocyte proliferationGO:00706611720.019
regulation of organelle organizationGO:00330432890.019
regulation of ossificationGO:00302781120.019
regulation of hydrolase activityGO:00513362460.019
positive regulation of cellular catabolic processGO:00313311480.019
activation of adenylate cyclase activityGO:000719040.019
protein transmembrane transportGO:007180680.019
angiogenesisGO:00015252010.019
purine nucleoside catabolic processGO:00061522050.019
oocyte axis specificationGO:000730920.019
cellular chemical homeostasisGO:00550822150.019
peptidyl amino acid modificationGO:00181933360.018
positive regulation of growthGO:00459271040.018
morphogenesis of a branching structureGO:00017632030.018
cytosolic calcium ion homeostasisGO:0051480700.018
cytokine productionGO:00018163190.018
fatty acid metabolic processGO:00066311210.018
response to lipopolysaccharideGO:00324961280.018
polysaccharide metabolic processGO:0005976390.018
interleukin 5 secretionGO:007260320.018
protein importGO:00170381010.018
regulation of cytoskeleton organizationGO:00514931220.018
epithelial tube morphogenesisGO:00605623030.018
negative regulation of molecular functionGO:00440922580.018
cell type specific apoptotic processGO:00972852680.018
cellular metal ion homeostasisGO:00068751510.018
positive regulation of gtp catabolic processGO:0033126850.018
cellular response to molecule of bacterial originGO:0071219830.018
apoptotic signaling pathwayGO:00971903060.018
establishment of organelle localizationGO:00516561220.018
regulation of secretion by cellGO:19035302490.018
heterocycle catabolic processGO:00467002800.018
locomotory behaviorGO:00076261950.017
cellular homeostasisGO:00197252400.017
muscle tissue developmentGO:00605373080.017
striated muscle tissue developmentGO:00147062930.017
cellular divalent inorganic cation homeostasisGO:00725031270.017
regulation of synaptic growth at neuromuscular junctionGO:000858240.017
gtp metabolic processGO:00460391440.017
nucleotide biosynthetic processGO:0009165780.017
single organism nuclear importGO:1902593950.017
response to light stimulusGO:00094161350.017
positive regulation of nucleotide catabolic processGO:0030813880.017
positive regulation of apoptotic processGO:00430652170.017
cellular ion homeostasisGO:00068731650.017
hormone secretionGO:00468791280.017
positive regulation of hydrolase activityGO:00513451480.017
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.017
reproductive behaviorGO:0019098320.016
embryonic digit morphogenesisGO:0042733560.016
endochondral bone morphogenesisGO:0060350500.016
negative regulation of phosphorus metabolic processGO:00105631840.016
calcium ion homeostasisGO:00550741270.016
purine ribonucleoside metabolic processGO:00461282410.016
cellular response to organonitrogen compoundGO:00714171450.016
positive regulation of cell migrationGO:00303351090.016
carboxylic acid catabolic processGO:0046395510.016
regulation of cell cell adhesion mediated by cadherinGO:200004720.016
ribonucleoside catabolic processGO:00424542060.016
purine nucleoside triphosphate catabolic processGO:00091462030.016
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.016
ribonucleoside triphosphate catabolic processGO:00092031990.016
regulation of neuron differentiationGO:00456642810.016
spermatid developmentGO:00072861080.016
inorganic ion transmembrane transportGO:00986602340.016
establishment of protein localization to peroxisomeGO:007266340.016
cation homeostasisGO:00550802120.016
fatty acid transmembrane transportGO:190200110.016
organelle fissionGO:00482851700.016
positive regulation of response to woundingGO:1903036660.015
lipid transportGO:0006869980.015
cellular macromolecule catabolic processGO:00442652060.015
posttranscriptional regulation of gene expressionGO:00106081550.015
negative regulation of phosphorylationGO:00423261660.015
regulation of actin cytoskeleton organizationGO:0032956840.015
positive regulation of protein phosphorylationGO:00019342420.015
purine ribonucleoside catabolic processGO:00461302050.015
protein localization to peroxisomeGO:007266240.015
organelle localizationGO:00516401790.015
cellular response to dna damage stimulusGO:00069742070.015
response to growth factorGO:00708481980.015
action potentialGO:0001508780.015
establishment of protein localization to membraneGO:0090150540.015
regulation of blood circulationGO:1903522930.015
carbohydrate homeostasisGO:00335001280.015
regulation of protein complex assemblyGO:0043254830.015
maintenance of locationGO:0051235890.015
regulation of ras protein signal transductionGO:00465781140.015
fatty acid oxidationGO:0019395280.015
regulation of multi organism processGO:00439001110.015
purine nucleotide metabolic processGO:00061633020.015
digestive system developmentGO:00551232000.015
regulation of cellular response to stressGO:00801351590.015
respiratory system developmentGO:00605411900.015
regulation of feeding behaviorGO:006025930.015
peptidyl tyrosine phosphorylationGO:00181081430.015
positive regulation of secretion by cellGO:19035321140.015
chondrocyte differentiationGO:0002062720.014
t cell activationGO:00421102890.014
extracellular matrix organizationGO:00301981470.014
heart contractionGO:0060047930.014
cyclic nucleotide metabolic processGO:0009187590.014
positive regulation of cytosolic calcium ion concentrationGO:0007204650.014
alpha amino acid metabolic processGO:1901605590.014
nephron epithelium developmentGO:0072009920.014
photoreceptor cell developmentGO:0042461400.014
cognitionGO:00508901490.014
positive regulation of protein modification processGO:00314012990.014
response to endoplasmic reticulum stressGO:0034976530.014
lipid biosynthetic processGO:00086101790.014
positive regulation of nervous system developmentGO:00519622210.014
sensory perception of mechanical stimulusGO:00509541070.014
negative regulation of cell adhesionGO:0007162450.014
regulation of defense responseGO:00313472330.014
ribonucleotide metabolic processGO:00092592910.014
central nervous system neuron differentiationGO:00219531620.014
positive regulation of camp biosynthetic processGO:0030819190.014
peptide transportGO:00158331330.014
lymphocyte differentiationGO:00300982420.014
energy reserve metabolic processGO:0006112390.014
regulation of antimicrobial humoral responseGO:000275930.014
inflammatory responseGO:00069542440.014
energy derivation by oxidation of organic compoundsGO:0015980770.013
morphogenesis of a branching epitheliumGO:00611381930.013
multi organism behaviorGO:0051705620.013
tissue homeostasisGO:00018941150.013
regulation of myeloid cell differentiationGO:0045637960.013
cellular response to growth factor stimulusGO:00713631970.013
negative regulation of cell motilityGO:2000146610.013
negative regulation of cellular amino acid metabolic processGO:004576300.013
regulation of mitotic cell cycleGO:00073461260.013
plasma membrane organizationGO:0007009900.013
protein import into peroxisome matrixGO:001655830.013
regulation of organ morphogenesisGO:20000271440.013
telencephalon developmentGO:00215371860.013
myeloid leukocyte differentiationGO:00025731190.013
muscle cell differentiationGO:00426922610.013
nucleoside triphosphate metabolic processGO:00091412300.013
protein targeting to peroxisomeGO:000662540.013
pallium developmentGO:00215431200.013
positive regulation of cytokine productionGO:00018191740.013
positive regulation of ion transportGO:0043270650.013
negative regulation of fatty acid transportGO:200019210.013
regulation of nucleoside metabolic processGO:00091181300.013
regulation of response to woundingGO:19030341890.013
negative regulation of cell proliferationGO:00082852960.013
divalent metal ion transportGO:00708381720.013
positive regulation of nucleotide biosynthetic processGO:0030810260.013
lipid localizationGO:00108761260.013
response to starvationGO:0042594650.013
cell growthGO:00160491300.012
protein kinase b signalingGO:0043491740.012
cellular calcium ion homeostasisGO:00068741190.012
negative regulation of cellular component organizationGO:00511291940.012
membrane organizationGO:00610242450.012
pigmentationGO:0043473710.012
glycoprotein biosynthetic processGO:0009101890.012
regulation of vesicle mediated transportGO:00606271390.012
regulation of reproductive processGO:2000241660.012
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.012
heart processGO:0003015940.012
asymmetric stem cell divisionGO:009872230.012
hematopoietic progenitor cell differentiationGO:00022441430.012
retrograde transport endosome to golgiGO:004214720.012
immune effector processGO:00022523210.012
regulation of mapk cascadeGO:00434082480.012
regulation of nucleotide catabolic processGO:00308111220.012
rhythmic processGO:00485111740.012
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus developmentGO:006052840.012
regulation of transferase activityGO:00513382630.012
telencephalon cell migrationGO:0022029550.012
protein ubiquitinationGO:00165671710.012
nucleoside catabolic processGO:00091642060.012
female sex differentiationGO:0046660840.012
cholesterol homeostasisGO:0042632440.012
glycerophospholipid metabolic processGO:0006650710.012
anatomical structure homeostasisGO:00602491450.012
guanosine containing compound metabolic processGO:19010681440.012
regulation of lymphocyte proliferationGO:00506701170.012
apical constrictionGO:000338340.012
response to peptide hormoneGO:00434341270.012
positive regulation of programmed cell deathGO:00430682180.012
nucleoside phosphate biosynthetic processGO:1901293790.012
protein processingGO:00164851630.012
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188540.012
glycerophospholipid biosynthetic processGO:0046474320.012
regulation of t cell activationGO:00508631700.012
reactive oxygen species metabolic processGO:0072593840.012
ameboidal type cell migrationGO:00016671280.012
response to molecule of bacterial originGO:00022371430.012
bone morphogenesisGO:0060349780.012
regulation of anatomical structure sizeGO:00900661780.012
multicellular organismal homeostasisGO:00488711640.012
divalent inorganic cation transportGO:00725111780.011
negative regulation of cellular amine metabolic processGO:003323910.011
epithelial cell developmentGO:00020641590.011
regulation of cell cycle processGO:00105641600.011
antimicrobial peptide biosynthetic processGO:000277720.011
digestive tract developmentGO:00485651900.011
insulin secretionGO:0030073890.011
cellularizationGO:000734910.011
stem cell proliferationGO:00720891170.011
rna processingGO:00063961050.011
female gonad developmentGO:0008585710.011
cellular response to peptide hormone stimulusGO:0071375920.011
regulation of inflammatory responseGO:00507271470.011
fertilizationGO:00095661270.011
nuclear transportGO:00511691390.011
dna methylationGO:0006306430.011
organ growthGO:00352651170.011
generation of precursor metabolites and energyGO:00060911030.011
regulation of cell activationGO:00508652890.011
cation transmembrane transportGO:00986552660.011
regulation of proteasomal protein catabolic processGO:0061136460.011
positive regulation of cyclic nucleotide metabolic processGO:0030801240.011
regulation of osteoclast differentiationGO:0045670360.011
reactive nitrogen species metabolic processGO:200105700.011
positive regulation of cell deathGO:00109422240.011
lens development in camera type eyeGO:0002088620.011
cerebral cortex developmentGO:0021987860.011
plasma membrane long chain fatty acid transportGO:001591110.011
positive regulation of protein serine threonine kinase activityGO:00719021060.011
response to peptideGO:19016521360.011
nucleoside triphosphate catabolic processGO:00091432050.011
regulation of peptide hormone secretionGO:0090276750.011
skeletal muscle organ developmentGO:00605381630.011
response to acid chemicalGO:00011011110.011
nuclear divisionGO:00002801580.011
lipid modificationGO:0030258650.011
cellular response to biotic stimulusGO:0071216920.011
regulation of cytokine productionGO:00018172660.011
ribonucleoside metabolic processGO:00091192450.011
habituationGO:004695930.011
cellular response to lipopolysaccharideGO:0071222770.011
dna alkylationGO:0006305430.011
activation of mapk activityGO:0000187590.011
retinal cone cell differentiationGO:004267080.011
wound healingGO:00420601570.011
negative regulation of cell activationGO:00508661110.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.011
peroxisomal transportGO:004357440.011
ribonucleoside triphosphate metabolic processGO:00091992200.011
regulation of protein secretionGO:0050708820.010
cellular response to acid chemicalGO:0071229680.010
exocytosisGO:00068871210.010
regulation of protein oligomerizationGO:003245940.010
peptide secretionGO:00027901140.010
camp metabolic processGO:0046058400.010
regulation of myeloid leukocyte differentiationGO:0002761580.010
peptide hormone secretionGO:00300721090.010
regulation of hormone secretionGO:0046883880.010
development of primary female sexual characteristicsGO:0046545730.010
b cell proliferationGO:0042100530.010
alpha beta t cell differentiationGO:0046632690.010
regulation of stem cell proliferationGO:0072091780.010
sensory perceptionGO:00076002450.010
positive regulation of neuron projection regenerationGO:007057220.010
lateral inhibitionGO:004633110.010
negative regulation of translational initiationGO:004594740.010
establishment of tissue polarityGO:0007164280.010
response to inorganic substanceGO:0010035960.010
cellular response to organic cyclic compoundGO:0071407870.010
regulation of apoptotic signaling pathwayGO:20012331970.010
regulation of kinase activityGO:00435492490.010
lymphocyte proliferationGO:00466511640.010
regulation of lymphocyte activationGO:00512492400.010

Akt1s1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.041
disease of anatomical entityDOID:700.041
central nervous system diseaseDOID:33100.032
brain diseaseDOID:93600.026
musculoskeletal system diseaseDOID:1700.023
disease of metabolismDOID:001466700.017
disease of cellular proliferationDOID:1456600.013
connective tissue diseaseDOID:6500.013
cancerDOID:16200.012
muscular diseaseDOID:008000000.012
organ system cancerDOID:005068600.011
bone diseaseDOID:008000100.010