IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Neu2

neuraminidase 2

(Aliases: MTS,MSS,MBS)

Entrez: 23956
Ensembl: ENSMUSG00000079434
UniProtKB: Q0VGI4
UniProtKB: Q9JMH3
UniProtKB: E9Q0I0
UniProtKB: Q3ULV6
UniProtKB: C0KJU9

Process Predictions
Disease Predictions

Neu2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
cation transport	GO:0006812	399	0.186
transmembrane transport	GO:0055085	412	0.136
cation transmembrane transport	GO:0098655	266	0.082
divalent inorganic cation transport	GO:0072511	178	0.066
ion transmembrane transport	GO:0034220	361	0.066
monocarboxylic acid metabolic process	GO:0032787	191	0.062
synaptic transmission	GO:0007268	329	0.059
organic anion transport	GO:0015711	137	0.057
oxidation reduction process	GO:0055114	342	0.056
calcium ion transport	GO:0006816	159	0.054
divalent metal ion transport	GO:0070838	172	0.051
purine nucleotide metabolic process	GO:0006163	302	0.051
cellular ketone metabolic process	GO:0042180	84	0.047
inorganic cation transmembrane transport	GO:0098662	207	0.045
nitrogen compound transport	GO:0071705	271	0.044
organic acid transport	GO:0015849	101	0.043
cellular lipid metabolic process	GO:0044255	323	0.043
regulation of cellular amine metabolic process	GO:0033238	20	0.040
nucleoside metabolic process	GO:0009116	246	0.040
amine metabolic process	GO:0009308	45	0.040
inorganic ion transmembrane transport	GO:0098660	234	0.039
muscle system process	GO:0003012	141	0.039
aromatic compound catabolic process	GO:0019439	286	0.038
regulation of transferase activity	GO:0051338	263	0.037
regulation of system process	GO:0044057	200	0.037
cytoplasmic transport	GO:0016482	234	0.037
neurotransmitter transport	GO:0006836	76	0.037
organic hydroxy compound metabolic process	GO:1901615	203	0.036
regulation of kinase activity	GO:0043549	249	0.036
cellular nitrogen compound catabolic process	GO:0044270	280	0.035
lipid biosynthetic process	GO:0008610	179	0.035
male gamete generation	GO:0048232	285	0.034
cellular alcohol biosynthetic process	GO:0044108	3	0.034
cellular amino acid metabolic process	GO:0006520	103	0.034
carboxylic acid transport	GO:0046942	100	0.034
maintenance of location	GO:0051235	89	0.034
g protein coupled receptor signaling pathway	GO:0007186	243	0.034
purine ribonucleoside metabolic process	GO:0046128	241	0.033
cellular amine metabolic process	GO:0044106	44	0.032
apoptotic signaling pathway	GO:0097190	306	0.032
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.031
muscle cell development	GO:0055001	133	0.030
organonitrogen compound catabolic process	GO:1901565	264	0.030
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.029
muscle tissue development	GO:0060537	308	0.029
organic hydroxy compound transport	GO:0015850	93	0.029
nucleobase containing small molecule metabolic process	GO:0055086	352	0.028
nucleotide metabolic process	GO:0009117	332	0.028
regulation of hormone levels	GO:0010817	211	0.028
extrinsic apoptotic signaling pathway	GO:0097191	126	0.028
response to organonitrogen compound	GO:0010243	246	0.028
secondary alcohol metabolic process	GO:1902652	3	0.028
glycosyl compound metabolic process	GO:1901657	246	0.028
cellular homeostasis	GO:0019725	240	0.028
muscle cell differentiation	GO:0042692	261	0.027
fatty acid metabolic process	GO:0006631	121	0.027
organic cyclic compound catabolic process	GO:1901361	295	0.027
purine ribonucleoside catabolic process	GO:0046130	205	0.027
response to organic cyclic compound	GO:0014070	198	0.026
ribose phosphate metabolic process	GO:0019693	291	0.026
purine containing compound metabolic process	GO:0072521	311	0.026
purine nucleoside metabolic process	GO:0042278	241	0.026
vitamin d3 metabolic process	GO:0070640	3	0.026
macromolecule catabolic process	GO:0009057	281	0.026
regulation of feeding behavior	GO:0060259	3	0.024
small molecule biosynthetic process	GO:0044283	132	0.024
nucleoside catabolic process	GO:0009164	206	0.024
cellular ion homeostasis	GO:0006873	165	0.024
regulation of protein localization	GO:0032880	231	0.023
positive regulation of cellular amine metabolic process	GO:0033240	5	0.023
anion transport	GO:0006820	177	0.023
cellular chemical homeostasis	GO:0055082	215	0.023
cellular alcohol metabolic process	GO:0044107	3	0.023
cellular macromolecule catabolic process	GO:0044265	206	0.023
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.023
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.023
response to growth factor	GO:0070848	198	0.022
wound healing	GO:0042060	157	0.022
cellular response to growth factor stimulus	GO:0071363	197	0.022
sequestering of calcium ion	GO:0051208	18	0.022
ribonucleoside catabolic process	GO:0042454	206	0.022
nucleoside triphosphate metabolic process	GO:0009141	230	0.022
positive regulation of protein modification process	GO:0031401	299	0.022
small gtpase mediated signal transduction	GO:0007264	97	0.022
regulation of cellular amino acid metabolic process	GO:0006521	5	0.022
peptidyl amino acid modification	GO:0018193	336	0.022
positive regulation of hydrolase activity	GO:0051345	148	0.022
epithelial cell proliferation	GO:0050673	174	0.021
amino acid transport	GO:0006865	61	0.021
amino acid transmembrane transport	GO:0003333	37	0.021
skeletal muscle organ development	GO:0060538	163	0.021
regulation of cellular ketone metabolic process	GO:0010565	66	0.021
heterocycle catabolic process	GO:0046700	280	0.021
positive regulation of protein kinase activity	GO:0045860	144	0.021
gtp catabolic process	GO:0006184	143	0.021
regulation of purine nucleotide metabolic process	GO:1900542	169	0.021
regulation of nucleoside metabolic process	GO:0009118	130	0.021
organic acid biosynthetic process	GO:0016053	86	0.021
organonitrogen compound biosynthetic process	GO:1901566	192	0.021
regulation of ion transport	GO:0043269	215	0.021
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.021
ras protein signal transduction	GO:0007265	77	0.021
epithelial cell development	GO:0002064	159	0.021
nucleoside triphosphate catabolic process	GO:0009143	205	0.020
regulation of establishment of protein localization	GO:0070201	181	0.020
regulation of cellular catabolic process	GO:0031329	242	0.020
striated muscle tissue development	GO:0014706	293	0.020
protein targeting	GO:0006605	143	0.020
regulation of hydrolase activity	GO:0051336	246	0.020
regulation of cellular response to stress	GO:0080135	159	0.020
intracellular protein transport	GO:0006886	204	0.020
calcitriol biosynthetic process from calciol	GO:0036378	3	0.020
regulation of intracellular transport	GO:0032386	159	0.020
purine ribonucleotide catabolic process	GO:0009154	208	0.020
regulation of secretion	GO:0051046	274	0.020
sodium ion export	GO:0071436	2	0.020
ribonucleoside metabolic process	GO:0009119	245	0.020
lipid localization	GO:0010876	126	0.020
angiogenesis	GO:0001525	201	0.020
norepinephrine transport	GO:0015874	2	0.020
regulation of apoptotic signaling pathway	GO:2001233	197	0.019
negative regulation of phosphate metabolic process	GO:0045936	184	0.019
purine ribonucleotide metabolic process	GO:0009150	290	0.019
regulation of anatomical structure size	GO:0090066	178	0.019
cognition	GO:0050890	149	0.019
carbohydrate derivative biosynthetic process	GO:1901137	183	0.019
regulation of neuron differentiation	GO:0045664	281	0.019
membrane organization	GO:0061024	245	0.019
cation homeostasis	GO:0055080	212	0.019
nuclear transport	GO:0051169	139	0.019
ribonucleotide metabolic process	GO:0009259	291	0.019
cellular response to cytokine stimulus	GO:0071345	189	0.019
drug catabolic process	GO:0042737	2	0.019
cell junction organization	GO:0034330	77	0.019
ribonucleotide catabolic process	GO:0009261	208	0.019
anion transmembrane transport	GO:0098656	71	0.018
sequestering of metal ion	GO:0051238	19	0.018
cellular response to hormone stimulus	GO:0032870	150	0.018
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.018
negative regulation of phosphorylation	GO:0042326	166	0.018
endocytosis	GO:0006897	168	0.018
cofactor metabolic process	GO:0051186	80	0.018
amide transport	GO:0042886	138	0.018
learning or memory	GO:0007611	148	0.018
spermatogenesis	GO:0007283	284	0.018
cellular metal ion homeostasis	GO:0006875	151	0.018
protein modification by small protein conjugation or removal	GO:0070647	207	0.018
circulatory system process	GO:0003013	197	0.018
sodium ion transport	GO:0006814	73	0.018
regulation of protein transport	GO:0051223	163	0.018
negative regulation of cellular protein metabolic process	GO:0032269	247	0.018
metal ion homeostasis	GO:0055065	189	0.018
vascular process in circulatory system	GO:0003018	62	0.018
positive regulation of transferase activity	GO:0051347	167	0.017
carbohydrate derivative catabolic process	GO:1901136	231	0.017
lipid transport	GO:0006869	98	0.017
protein modification by small protein conjugation	GO:0032446	187	0.017
myotube differentiation	GO:0014902	105	0.017
regulation of secretion by cell	GO:1903530	249	0.017
nucleotide catabolic process	GO:0009166	217	0.017
muscle fiber development	GO:0048747	76	0.017
response to nutrient levels	GO:0031667	109	0.017
striated muscle cell development	GO:0055002	125	0.017
guanosine containing compound catabolic process	GO:1901069	144	0.017
nucleoside phosphate metabolic process	GO:0006753	338	0.017
response to light stimulus	GO:0009416	135	0.017
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.017
cellular response to organonitrogen compound	GO:0071417	145	0.017
positive regulation of nucleotide metabolic process	GO:0045981	114	0.017
mitochondrion organization	GO:0007005	134	0.017
regulation of metal ion transport	GO:0010959	106	0.016
nucleoside phosphate catabolic process	GO:1901292	222	0.016
positive regulation of cell development	GO:0010720	237	0.016
hematopoietic progenitor cell differentiation	GO:0002244	143	0.016
regulation of protein kinase activity	GO:0045859	232	0.016
glycosyl compound catabolic process	GO:1901658	206	0.016
organophosphate catabolic process	GO:0046434	232	0.016
regulation of nucleotide catabolic process	GO:0030811	122	0.016
regulation of nucleotide metabolic process	GO:0006140	169	0.016
regulation of neurotransmitter levels	GO:0001505	87	0.016
renal tubular secretion	GO:0097254	2	0.016
purine containing compound catabolic process	GO:0072523	213	0.016
purine nucleoside catabolic process	GO:0006152	205	0.016
inflammatory response	GO:0006954	244	0.016
carbohydrate metabolic process	GO:0005975	230	0.016
hormone metabolic process	GO:0042445	86	0.016
glycerolipid metabolic process	GO:0046486	122	0.016
blood circulation	GO:0008015	195	0.016
dna metabolic process	GO:0006259	303	0.016
nucleocytoplasmic transport	GO:0006913	139	0.016
regulation of cell activation	GO:0050865	289	0.016
response to radiation	GO:0009314	165	0.015
purine nucleotide catabolic process	GO:0006195	211	0.015
regulation of extrinsic apoptotic signaling pathway	GO:2001236	77	0.015
regulation of body fluid levels	GO:0050878	162	0.015
negative regulation of phosphorus metabolic process	GO:0010563	184	0.015
locomotory behavior	GO:0007626	195	0.015
regulation of cell cycle process	GO:0010564	160	0.015
protein localization to organelle	GO:0033365	185	0.015
regulation of protein serine threonine kinase activity	GO:0071900	157	0.015
calcium ion homeostasis	GO:0055074	127	0.015
regulation of tube size	GO:0035150	57	0.015
response to inorganic substance	GO:0010035	96	0.015
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.015
cell adhesion	GO:0007155	329	0.015
response to extracellular stimulus	GO:0009991	127	0.015
positive regulation of protein phosphorylation	GO:0001934	242	0.015
regulation of organelle organization	GO:0033043	289	0.015
reactive nitrogen species metabolic process	GO:2001057	0	0.015
monocarboxylic acid transport	GO:0015718	44	0.015
positive regulation of cellular catabolic process	GO:0031331	148	0.014
regulation of purine nucleotide catabolic process	GO:0033121	122	0.014
skeletal muscle fiber development	GO:0048741	58	0.014
engulfment of apoptotic cell	GO:0043652	3	0.014
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.014
protein ubiquitination	GO:0016567	171	0.014
regulation of cytoplasmic transport	GO:1903649	112	0.014
renal system development	GO:0072001	225	0.014
leukocyte proliferation	GO:0070661	172	0.014
monosaccharide metabolic process	GO:0005996	106	0.014
cell cell junction organization	GO:0045216	72	0.014
regulation of circadian sleep wake cycle	GO:0042749	3	0.014
regulation of cellular component biogenesis	GO:0044087	181	0.014
endomembrane system organization	GO:0010256	147	0.014
skin development	GO:0043588	220	0.014
retrograde transport endosome to golgi	GO:0042147	2	0.014
hormone secretion	GO:0046879	128	0.014
cytokine secretion	GO:0050663	72	0.014
negative regulation of cellular component organization	GO:0051129	194	0.014
hexose transport	GO:0008645	56	0.014
glucose homeostasis	GO:0042593	128	0.013
establishment of protein localization to organelle	GO:0072594	118	0.013
positive regulation of secretion	GO:0051047	130	0.013
organophosphate biosynthetic process	GO:0090407	122	0.013
coenzyme metabolic process	GO:0006732	52	0.013
sensory perception	GO:0007600	245	0.013
cellular modified amino acid metabolic process	GO:0006575	63	0.013
neurotransmitter secretion	GO:0007269	62	0.013
negative regulation of cell proliferation	GO:0008285	296	0.013
multicellular organismal signaling	GO:0035637	91	0.013
response to acid chemical	GO:0001101	111	0.013
regulation of epithelial cell proliferation	GO:0050678	141	0.013
transmission of nerve impulse	GO:0019226	76	0.013
regulation of cytokine production	GO:0001817	266	0.013
cytokine production	GO:0001816	319	0.013
carbohydrate homeostasis	GO:0033500	128	0.013
t cell activation	GO:0042110	289	0.013
cellular protein complex assembly	GO:0043623	116	0.013
regulation of blood vessel size	GO:0050880	56	0.013
positive regulation of kinase activity	GO:0033674	155	0.013
regulation of lymphocyte activation	GO:0051249	240	0.013
regulation of homeostatic process	GO:0032844	182	0.013
negative regulation of protein modification process	GO:0031400	163	0.013
response to oxygen levels	GO:0070482	62	0.012
muscle contraction	GO:0006936	101	0.012
response to starvation	GO:0042594	65	0.012
establishment of blood nerve barrier	GO:0008065	3	0.012
establishment of vesicle localization	GO:0051650	81	0.012
organelle fission	GO:0048285	170	0.012
adult locomotory behavior	GO:0008344	91	0.012
myeloid leukocyte differentiation	GO:0002573	119	0.012
protein localization to nucleus	GO:0034504	121	0.012
leukocyte differentiation	GO:0002521	342	0.012
ossification	GO:0001503	216	0.012
carbohydrate transport	GO:0008643	62	0.012
regulation of response to wounding	GO:1903034	189	0.012
protein catabolic process	GO:0030163	221	0.012
naphthalene containing compound metabolic process	GO:0090420	1	0.012
regulation of muscle tissue development	GO:1901861	97	0.012
cell division	GO:0051301	120	0.012
organic hydroxy compound biosynthetic process	GO:1901617	77	0.012
regulation of hormone secretion	GO:0046883	88	0.012
positive regulation of purine nucleotide catabolic process	GO:0033123	88	0.012
regulation of muscle system process	GO:0090257	80	0.012
protein import into nucleus	GO:0006606	95	0.012
response to peptide hormone	GO:0043434	127	0.012
norepinephrine secretion	GO:0048243	2	0.012
rna processing	GO:0006396	105	0.012
positive regulation of secretion by cell	GO:1903532	114	0.012
cellular response to extracellular stimulus	GO:0031668	81	0.012
protein localization to membrane	GO:0072657	108	0.012
carboxylic acid biosynthetic process	GO:0046394	86	0.012
mrna metabolic process	GO:0016071	84	0.012
regulation of blood pressure	GO:0008217	93	0.012
peptide transport	GO:0015833	133	0.012
mitotic cell cycle	GO:0000278	195	0.012
atp metabolic process	GO:0046034	75	0.012
action potential	GO:0001508	78	0.012
porphyrin containing compound metabolic process	GO:0006778	22	0.012
membrane lipid biosynthetic process	GO:0046467	32	0.011
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.011
regulation of striated muscle cell differentiation	GO:0051153	81	0.011
gtp metabolic process	GO:0046039	144	0.011
positive regulation of nucleotide catabolic process	GO:0030813	88	0.011
negative regulation of cellular amine metabolic process	GO:0033239	1	0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.011
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.011
regulation of membrane potential	GO:0042391	192	0.011
cellular response to lipid	GO:0071396	145	0.011
cell junction assembly	GO:0034329	52	0.011
wnt signaling pathway	GO:0016055	188	0.011
alcohol metabolic process	GO:0006066	116	0.011
vitamin d biosynthetic process	GO:0042368	3	0.011
multi multicellular organism process	GO:0044706	109	0.011
digestion	GO:0007586	40	0.011
feeding behavior	GO:0007631	62	0.011
lymphocyte proliferation	GO:0046651	164	0.011
positive regulation of nucleoside metabolic process	GO:0045979	91	0.011
cytosolic calcium ion homeostasis	GO:0051480	70	0.011
immune effector process	GO:0002252	321	0.011
xenobiotic catabolic process	GO:0042178	1	0.011
calcium mediated signaling	GO:0019722	46	0.011
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.011
divalent inorganic cation homeostasis	GO:0072507	138	0.011
developmental growth involved in morphogenesis	GO:0060560	138	0.011
heart process	GO:0003015	94	0.011
regulation of circadian sleep wake cycle sleep	GO:0045187	3	0.011
carnitine transport	GO:0015879	3	0.011
actin cytoskeleton organization	GO:0030036	220	0.011
myotube cell development	GO:0014904	60	0.011
stress activated mapk cascade	GO:0051403	80	0.011
protein import	GO:0017038	101	0.011
rhythmic process	GO:0048511	174	0.011
negative regulation of male mating behavior	GO:1902436	1	0.011
negative regulation of intracellular signal transduction	GO:1902532	167	0.011
methylation	GO:0032259	134	0.011
multicellular organismal homeostasis	GO:0048871	164	0.010
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.010
response to oxidative stress	GO:0006979	123	0.010
spermatid differentiation	GO:0048515	115	0.010
regulation of cell cycle	GO:0051726	281	0.010
response to lipopolysaccharide	GO:0032496	128	0.010
plasma membrane organization	GO:0007009	90	0.010
epithelial tube morphogenesis	GO:0060562	303	0.010
modification dependent macromolecule catabolic process	GO:0043632	133	0.010
positive regulation of proteolysis	GO:0045862	85	0.010
cell substrate adhesion	GO:0031589	130	0.010
cellular response to external stimulus	GO:0071496	88	0.010
phospholipid metabolic process	GO:0006644	87	0.010
positive regulation of leukocyte proliferation	GO:0070665	73	0.010
organelle localization	GO:0051640	179	0.010
lipid homeostasis	GO:0055088	63	0.010
oligopeptide transmembrane transport	GO:0035672	4	0.010
regulation of binding	GO:0051098	111	0.010
nucleoside phosphate biosynthetic process	GO:1901293	79	0.010
leukocyte activation involved in immune response	GO:0002366	126	0.010
second messenger mediated signaling	GO:0019932	73	0.010
negative regulation of protein phosphorylation	GO:0001933	126	0.010

Neu2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.021
musculoskeletal system disease	DOID:17	0.021
nervous system disease	DOID:863	0.019
disease of cellular proliferation	DOID:14566	0.014
cancer	DOID:162	0.013
organ system cancer	DOID:0050686	0.013
neurodegenerative disease	DOID:1289	0.011
central nervous system disease	DOID:331	0.011
connective tissue disease	DOID:65	0.011

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network