Mus musculus

66 known processes

Tardbp

TAR DNA binding protein

(Aliases: C85084,Tdp43,TDP-43,1190002A23Rik)

Tardbp biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rna splicingGO:0008380540.972
Human
mrna splicing via spliceosomeGO:0000398430.942
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.910
rna splicing via transesterification reactionsGO:0000375430.820
regulation of mrna splicing via spliceosomeGO:0048024320.818
mrna metabolic processGO:0016071840.801
rna processingGO:00063961050.772
Human
germ cell developmentGO:00072811850.714
spermatid differentiationGO:00485151150.673
nucleic acid transportGO:0050657180.586
mrna processingGO:0006397630.564
regulation of rna splicingGO:0043484370.534
mrna export from nucleusGO:0006406110.413
regulation of mrna metabolic processGO:1903311430.409
male gamete generationGO:00482322850.403
negative regulation of mrna splicing via spliceosomeGO:0048025120.390
oocyte constructionGO:000730820.357
spliceosomal complex assemblyGO:000024560.350
nucleobase containing compound transportGO:0015931270.321
posttranscriptional gene silencing by rnaGO:0035194100.298
regulation of mrna processingGO:0050684410.297
regulation of organelle organizationGO:00330432890.295
mitotic nuclear divisionGO:0007067480.280
alternative mrna splicing via spliceosomeGO:0000380120.278
regulation of translationGO:0006417710.276
development of primary sexual characteristicsGO:00451371430.267
negative regulation of cellular protein metabolic processGO:00322692470.263
translationGO:0006412930.256
mitotic cell cycleGO:00002781950.253
spermatogenesisGO:00072832840.251
negative regulation of rna splicingGO:0033119120.244
rna transportGO:0050658180.234
gene silencing by rnaGO:0031047190.222
regulation of cell cycleGO:00517262810.216
posttranscriptional regulation of gene expressionGO:00106081550.213
Human
regulation of dna templated transcription terminationGO:003155410.199
mrna transportGO:0051028130.192
negative regulation of mrna metabolic processGO:1903312130.180
spermatid developmentGO:00072861080.178
rna interferenceGO:001624620.159
cell divisionGO:00513011200.156
cytoplasmic transportGO:00164822340.152
negative regulation of mrna processingGO:0050686120.151
gonad developmentGO:00084061410.141
regulation of mrna stabilityGO:0043488230.141
Human
3 utr mediated mrna stabilizationGO:007093520.132
Human
response to heatGO:0009408270.125
regulation of cell cycle processGO:00105641600.122
protein complex disassemblyGO:0043241400.120
cellular nitrogen compound catabolic processGO:00442702800.117
ribonucleoprotein complex subunit organizationGO:0071826280.113
establishment of rna localizationGO:0051236180.113
negative regulation of protein metabolic processGO:00512482820.111
organic cyclic compound catabolic processGO:19013612950.106
genitalia developmentGO:0048806370.102
nuclear divisionGO:00002801580.101
oocyte axis specificationGO:000730920.101
ras protein signal transductionGO:0007265770.100
response to molecule of bacterial originGO:00022371430.098
nitrogen compound transportGO:00717052710.093
regulation of protein complex disassemblyGO:0043244280.093
regulation of neuron projection developmentGO:00109751690.093
dendrite developmentGO:00163581150.092
stem cell developmentGO:00488642190.085
mitotic cell cycle processGO:19030471590.084
microtubule cytoskeleton organizationGO:00002261570.081
rna localizationGO:0006403230.074
inflammatory responseGO:00069542440.074
dna templated transcription terminationGO:000635340.072
heterocycle catabolic processGO:00467002800.071
regionalizationGO:00030023370.070
rna stabilizationGO:004348990.069
Human
regulation of alternative mrna splicing via spliceosomeGO:000038180.069
female gamete generationGO:0007292740.068
regulation of rna stabilityGO:0043487260.063
Human
organelle fissionGO:00482851700.061
organelle localizationGO:00516401790.060
nuclear transportGO:00511691390.058
regulation of cytoskeleton organizationGO:00514931220.057
oocyte anterior posterior axis specificationGO:000731420.057
oogenesisGO:0048477560.055
rna 3 end processingGO:0031123200.054
meiotic cell cycleGO:00513211220.054
oocyte developmentGO:0048599330.053
developmental maturationGO:00217001930.051
regulation of mitotic cell cycleGO:00073461260.051
nucleocytoplasmic transportGO:00069131390.050
striated muscle contractionGO:0006941450.049
adult locomotory behaviorGO:0008344910.048
Fly
amine metabolic processGO:0009308450.047
mrna splice site selectionGO:000637650.047
stem cell differentiationGO:00488632680.046
mrna catabolic processGO:0006402220.046
cellular amine metabolic processGO:0044106440.045
aromatic compound catabolic processGO:00194392860.045
muscle contractionGO:00069361010.045
rna catabolic processGO:0006401290.044
establishment of organelle localizationGO:00516561220.044
nuclear exportGO:0051168340.043
skin developmentGO:00435882200.041
response to lipopolysaccharideGO:00324961280.041
ribonucleotide metabolic processGO:00092592910.040
ribonucleoside triphosphate metabolic processGO:00091992200.039
circulatory system processGO:00030131970.039
ribonucleoprotein complex localizationGO:007116610.037
intracellular protein transportGO:00068862040.037
negative regulation of dna templated transcription terminationGO:006056710.037
response to temperature stimulusGO:0009266550.036
regulation of protein localizationGO:00328802310.036
multi multicellular organism processGO:00447061090.036
macromolecular complex disassemblyGO:0032984430.034
maternal determination of anterior posterior axis embryoGO:000835820.033
positive regulation of organelle organizationGO:00106381280.033
cellular macromolecule catabolic processGO:00442652060.032
regulation of nuclear divisionGO:0051783560.032
meiotic nuclear divisionGO:00071261150.032
positive regulation of chromosome organizationGO:2001252330.032
termination of rna polymerase ii transcriptionGO:000636910.032
oxidation reduction processGO:00551143420.031
regulation of cellular component biogenesisGO:00440871810.031
Fly
nucleotide catabolic processGO:00091662170.030
regulation of apoptotic signaling pathwayGO:20012331970.030
protein localization to nucleusGO:00345041210.030
multicellular organismal agingGO:0010259240.030
nucleoside phosphate catabolic processGO:19012922220.029
multicellular organism growthGO:00352641610.029
negative regulation of cellular component organizationGO:00511291940.029
Fly
ossificationGO:00015032160.028
hematopoietic progenitor cell differentiationGO:00022441430.027
atp catabolic processGO:0006200550.027
regulation of cellular response to stressGO:00801351590.026
membrane organizationGO:00610242450.026
purine nucleoside metabolic processGO:00422782410.025
positive regulation of cell developmentGO:00107202370.025
stem cell maintenanceGO:00198271300.025
regulation of cell divisionGO:0051302760.025
cell maturationGO:00484691270.025
cell junction organizationGO:0034330770.025
macromolecule catabolic processGO:00090572810.024
ribonucleoside metabolic processGO:00091192450.024
cellular response to lipopolysaccharideGO:0071222770.024
microtubule based processGO:00070172360.023
nucleoside monophosphate metabolic processGO:0009123850.023
cellular ketone metabolic processGO:0042180840.023
determination of adult lifespanGO:0008340110.023
pole plasm assemblyGO:000731520.023
nuclear mrna surveillanceGO:007102810.022
protein localization to organelleGO:00333651850.022
epidermis developmentGO:00085441870.022
protein oligomerizationGO:0051259670.022
negative regulation of cell cycleGO:00457861230.022
regulation of cell cycle phase transitionGO:1901987770.022
purine containing compound metabolic processGO:00725213110.022
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018410.021
actin cytoskeleton organizationGO:00300362200.021
development of primary female sexual characteristicsGO:0046545730.021
regulation of cellular amine metabolic processGO:0033238200.021
nucleoside phosphate metabolic processGO:00067533380.021
apoptotic signaling pathwayGO:00971903060.020
cellular amino acid metabolic processGO:00065201030.020
adult behaviorGO:00305341350.020
Fly
body morphogenesisGO:0010171450.020
protein maturationGO:00516041760.020
regulation of cell projection organizationGO:00313442060.020
positive regulation of rna splicingGO:0033120120.019
negative regulation of protein modification processGO:00314001630.019
rrna containing ribonucleoprotein complex export from nucleusGO:007142810.019
cellular protein complex disassemblyGO:0043624360.019
positive regulation of neuron differentiationGO:00456661410.019
positive regulation of proteolysisGO:0045862850.019
regulation of ras protein signal transductionGO:00465781140.019
nucleoside metabolic processGO:00091162460.019
small gtpase mediated signal transductionGO:0007264970.019
epithelial cell proliferationGO:00506731740.019
chemotaxisGO:00069352470.019
purine nucleotide catabolic processGO:00061952110.018
endocytosisGO:00068971680.018
intracellular mrna localizationGO:000829840.018
negative regulation of keratinocyte differentiationGO:004561740.017
response to organonitrogen compoundGO:00102432460.017
posttranscriptional gene silencingGO:0016441100.017
nucleus organizationGO:0006997450.017
regulation of system processGO:00440572000.017
carbohydrate derivative catabolic processGO:19011362310.017
carbohydrate derivative biosynthetic processGO:19011371830.016
maintenance of locationGO:0051235890.016
phospholipid metabolic processGO:0006644870.016
compound eye developmentGO:004874910.016
cell growthGO:00160491300.016
Zebrafish
regulation of epidermis developmentGO:0045682330.016
negative regulation of cell cycle processGO:0010948690.016
heart processGO:0003015940.016
anatomical structure homeostasisGO:00602491450.015
negative regulation of translationGO:0017148220.015
female sex differentiationGO:0046660840.015
circadian rhythmGO:00076231140.015
protein localization to membraneGO:00726571080.015
positive regulation of growthGO:00459271040.015
cellular response to cytokine stimulusGO:00713451890.015
cellular response to organonitrogen compoundGO:00714171450.015
ribosomal subunit export from nucleusGO:000005410.015
fertilizationGO:00095661270.014
axonogenesisGO:00074092740.014
Zebrafish
cellular protein complex assemblyGO:00436231160.014
myosin filament organizationGO:003103330.014
blood circulationGO:00080151950.014
positive regulation of mrna processingGO:0050685160.014
cellularizationGO:000734910.014
neuron projection guidanceGO:00974851410.014
regulation of cellular ketone metabolic processGO:0010565660.014
pore complex assemblyGO:004693130.014
ribose phosphate metabolic processGO:00196932910.014
positive regulation of nervous system developmentGO:00519622210.013
negative regulation of molecular functionGO:00440922580.013
positive regulation of mrna metabolic processGO:1903313170.013
female gonad developmentGO:0008585710.013
ribonucleotide catabolic processGO:00092612080.013
regulation of meiotic cell cycleGO:0051445340.013
lipid localizationGO:00108761260.013
positive regulation of dendrite developmentGO:1900006210.013
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.013
myeloid cell differentiationGO:00300992330.013
gene silencingGO:0016458380.012
positive regulation of cellular amine metabolic processGO:003324050.012
dna metabolic processGO:00062593030.012
cell type specific apoptotic processGO:00972852680.012
glycosyl compound metabolic processGO:19016572460.012
generation of precursor metabolites and energyGO:00060911030.012
mitochondrion organizationGO:00070051340.012
regulation of multi organism processGO:00439001110.012
Human
purine ribonucleoside monophosphate metabolic processGO:0009167800.012
purine nucleoside catabolic processGO:00061522050.012
regulation of actin filament based processGO:0032970990.011
protein import into nucleusGO:0006606950.011
ribonucleoside catabolic processGO:00424542060.011
organophosphate catabolic processGO:00464342320.011
regulation of cell morphogenesis involved in differentiationGO:00107691510.011
segmentationGO:0035282930.011
nucleobase containing small molecule metabolic processGO:00550863520.011
poly a mrna export from nucleusGO:001697340.011
regulation of anatomical structure sizeGO:00900661780.011
regulation of cellular component sizeGO:00325351210.011
regulation of protein transportGO:00512231630.011
nucleoside catabolic processGO:00091642060.011
organelle assemblyGO:00709251770.011
negative regulation of cellular amino acid metabolic processGO:004576300.011
regulation of transferase activityGO:00513382630.010
regulation of chromatin modificationGO:1903308570.010
positive regulation of mrna splicing via spliceosomeGO:0048026110.010
regulation of mitotic cell cycle phase transitionGO:1901990730.010
nucleoside monophosphate catabolic processGO:0009125590.010
neuron migrationGO:00017641220.010
negative regulation of nervous system developmentGO:00519611560.010
Fly
ribonucleoside triphosphate catabolic processGO:00092031990.010

Tardbp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.049
Human
nervous system diseaseDOID:86300.049
Human
central nervous system diseaseDOID:33100.049
Human
muscle tissue diseaseDOID:6600.016
musculoskeletal system diseaseDOID:1700.016
muscular diseaseDOID:008000000.016
myopathyDOID:42300.016