Mus musculus

49 known processes

Pkhd1

polycystic kidney and hepatic disease 1

(Aliases: AI182499,Tigm1,AI118496,FPC)

Pkhd1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
urogenital system developmentGO:00016552610.466
kidney developmentGO:00018222130.388
ion transmembrane transportGO:00342203610.181
renal system developmentGO:00720012250.172
detection of chemical stimulus involved in sensory perception of tasteGO:005091230.158
nucleotide metabolic processGO:00091173320.128
purine nucleotide metabolic processGO:00061633020.124
purine ribonucleotide metabolic processGO:00091502900.112
positive regulation of dendritic spine morphogenesisGO:006100380.111
nucleoside phosphate metabolic processGO:00067533380.108
cation transportGO:00068123990.103
purine containing compound metabolic processGO:00725213110.101
gland developmentGO:00487323300.099
oxidation reduction processGO:00551143420.092
nucleobase containing small molecule metabolic processGO:00550863520.085
ribose phosphate metabolic processGO:00196932910.085
cellular ketone metabolic processGO:0042180840.083
metanephric loop of henle developmentGO:007223640.076
cellular homeostasisGO:00197252400.076
blood circulationGO:00080151950.073
carbohydrate derivative biosynthetic processGO:19011371830.063
retinoic acid metabolic processGO:0042573120.063
female gamete generationGO:0007292740.063
regulation of hormone levelsGO:00108172110.058
regulation of nucleotide metabolic processGO:00061401690.057
reactive nitrogen species metabolic processGO:200105700.056
cellular component assembly involved in morphogenesisGO:00109271390.056
cellular amine metabolic processGO:0044106440.053
ribonucleotide metabolic processGO:00092592910.053
regulation of ion transportGO:00432692150.051
monocarboxylic acid biosynthetic processGO:0072330610.051
organophosphate biosynthetic processGO:00904071220.050
ascending thin limb developmentGO:007202120.050
myeloid cell differentiationGO:00300992330.050
positive regulation of nervous system developmentGO:00519622210.050
placenta developmentGO:00018901400.049
anatomical structure homeostasisGO:00602491450.046
organic acid biosynthetic processGO:0016053860.046
mitotic cell cycleGO:00002781950.046
dna metabolic processGO:00062593030.045
organelle assemblyGO:00709251770.045
sensory perceptionGO:00076002450.043
protein localization to organelleGO:00333651850.043
cilium morphogenesisGO:00602711020.043
ear developmentGO:00435832000.042
nucleoside phosphate biosynthetic processGO:1901293790.042
metanephric ascending thin limb developmentGO:007221820.042
amine metabolic processGO:0009308450.041
monosaccharide metabolic processGO:00059961060.041
positive regulation of reactive oxygen species metabolic processGO:2000379110.040
response to acid chemicalGO:00011011110.039
myeloid leukocyte differentiationGO:00025731190.039
metal ion homeostasisGO:00550651890.039
cilium assemblyGO:0042384810.038
response to growth factorGO:00708481980.037
regulation of reactive oxygen species biosynthetic processGO:190342620.037
mitotic cell cycle processGO:19030471590.037
small molecule biosynthetic processGO:00442831320.036
developmental maturationGO:00217001930.036
organic acid transportGO:00158491010.036
reactive oxygen species biosynthetic processGO:190340980.036
regulation of neuron differentiationGO:00456642810.036
regulation of membrane potentialGO:00423911920.036
liver developmentGO:0001889660.036
anion transportGO:00068201770.035
cation homeostasisGO:00550802120.034
regulation of heart contractionGO:0008016770.034
carboxylic acid biosynthetic processGO:0046394860.033
aromatic compound catabolic processGO:00194392860.033
circulatory system processGO:00030131970.033
carnitine transportGO:001587930.032
nucleotide biosynthetic processGO:0009165780.032
regulation of protein localizationGO:00328802310.032
cellular chemical homeostasisGO:00550822150.032
carbohydrate metabolic processGO:00059752300.032
organonitrogen compound catabolic processGO:19015652640.032
response to inorganic substanceGO:0010035960.032
regulation of multi organism processGO:00439001110.032
camp metabolic processGO:0046058400.031
cellular response to dna damage stimulusGO:00069742070.031
cellular calcium ion homeostasisGO:00068741190.031
regulation of reactive oxygen species metabolic processGO:2000377400.031
cellular nitrogen compound catabolic processGO:00442702800.031
axonogenesisGO:00074092740.031
response to corticosteroneGO:005141210.030
forebrain developmentGO:00309003020.030
reactive oxygen species metabolic processGO:0072593840.030
spermatogenesisGO:00072832840.030
isoprenoid metabolic processGO:0006720290.030
response to organonitrogen compoundGO:00102432460.029
negative regulation of ryanodine sensitive calcium release channel activityGO:006031510.029
mapk cascadeGO:00001652810.028
locomotory behaviorGO:00076261950.028
macromolecule catabolic processGO:00090572810.028
regulation of protein serine threonine kinase activityGO:00719001570.028
androgen biosynthetic processGO:000670240.028
regulation of system processGO:00440572000.028
purine ribonucleotide biosynthetic processGO:0009152590.027
organic cyclic compound catabolic processGO:19013612950.027
cellular ion homeostasisGO:00068731650.027
negative regulation of cation channel activityGO:200125810.027
nephron tubule developmentGO:0072080840.027
regulation of metal ion transportGO:00109591060.027
retinoic acid biosynthetic processGO:000213870.026
purine nucleoside metabolic processGO:00422782410.026
inorganic cation transmembrane transportGO:00986622070.026
regulation of cell projection organizationGO:00313442060.026
cellular response to fluid shear stressGO:007149840.026
lipid biosynthetic processGO:00086101790.026
regulation of cellular response to stressGO:00801351590.026
carnitine transmembrane transportGO:190260330.026
diterpenoid biosynthetic processGO:001610270.026
muscle contractionGO:00069361010.026
transmembrane transportGO:00550854120.026
isoprenoid biosynthetic processGO:000829990.026
potassium ion transmembrane transportGO:0071805430.025
hormone metabolic processGO:0042445860.025
heart contractionGO:0060047930.025
regulation of purine nucleotide metabolic processGO:19005421690.025
hexose transportGO:0008645560.025
hexose metabolic processGO:0019318980.025
ribonucleoside catabolic processGO:00424542060.025
carboxylic acid transportGO:00469421000.025
carbohydrate transportGO:0008643620.025
regulation of cellular component biogenesisGO:00440871810.025
regulation of muscle system processGO:0090257800.024
regulation of microtubule based processGO:0032886520.024
regulation of transferase activityGO:00513382630.024
cellular response to lipidGO:00713961450.024
regulation of establishment of protein localizationGO:00702011810.024
glucose transportGO:0015758560.024
cell maturationGO:00484691270.024
purine ribonucleoside metabolic processGO:00461282410.024
regulation of camp metabolic processGO:0030814300.024
negative regulation of calcium ion transmembrane transporter activityGO:190102010.023
male gamete generationGO:00482322850.023
regulation of cellular amine metabolic processGO:0033238200.023
maintenance of locationGO:0051235890.023
synaptic transmissionGO:00072683290.023
second messenger mediated signalingGO:0019932730.023
cellular response to hormone stimulusGO:00328701500.022
regulation of proteolysisGO:00301621640.022
cyclic nucleotide metabolic processGO:0009187590.022
purine nucleoside triphosphate metabolic processGO:00091442260.022
response to mineralocorticoidGO:005138510.022
cytoplasmic transportGO:00164822340.022
positive regulation of reactive oxygen species biosynthetic processGO:190342820.022
organic hydroxy compound metabolic processGO:19016152030.022
endocytosisGO:00068971680.022
ribonucleotide biosynthetic processGO:0009260590.022
detection of nodal flowGO:000312720.022
purine containing compound biosynthetic processGO:0072522700.022
ribonucleoside metabolic processGO:00091192450.022
regulation of protein transportGO:00512231630.021
cellular protein catabolic processGO:00442571550.021
negative regulation of molecular functionGO:00440922580.021
nucleotide catabolic processGO:00091662170.021
ribonucleotide catabolic processGO:00092612080.021
monosaccharide transportGO:0015749580.021
carbohydrate derivative catabolic processGO:19011362310.021
ureteric bud developmentGO:0001657940.021
ribose phosphate biosynthetic processGO:0046390590.020
cellular macromolecule catabolic processGO:00442652060.020
regulation of cellular ketone metabolic processGO:0010565660.020
blood vessel morphogenesisGO:00485142850.020
amino acid transportGO:0006865610.020
g protein coupled receptor signaling pathwayGO:00071862430.020
purine nucleoside triphosphate catabolic processGO:00091462030.020
organic hydroxy compound transportGO:0015850930.020
organonitrogen compound biosynthetic processGO:19015661920.020
fatty acid metabolic processGO:00066311210.020
cyclic nucleotide biosynthetic processGO:0009190440.020
lipid homeostasisGO:0055088630.019
regulation of hydrolase activityGO:00513362460.019
muscle system processGO:00030121410.019
multicellular organismal signalingGO:0035637910.019
nucleoside triphosphate catabolic processGO:00091432050.019
positive regulation of dendrite developmentGO:1900006210.019
regulation of blood circulationGO:1903522930.019
heterocycle catabolic processGO:00467002800.019
digestive system developmentGO:00551232000.019
regulation of cellular catabolic processGO:00313292420.019
purine ribonucleoside triphosphate metabolic processGO:00092052200.019
lipid localizationGO:00108761260.019
metanephros developmentGO:0001656790.019
regulation of kinase activityGO:00435492490.019
embryonic limb morphogenesisGO:00303261260.019
defense response to bacteriumGO:00427421190.018
nucleoside catabolic processGO:00091642060.018
t cell activationGO:00421102890.018
establishment of protein localization to organelleGO:00725941180.018
cell adhesionGO:00071553290.018
inorganic ion transmembrane transportGO:00986602340.018
regulation of secretionGO:00510462740.018
regulation of body fluid levelsGO:00508781620.018
proximal convoluted tubule developmentGO:007201910.018
9 cis retinoic acid metabolic processGO:004290550.018
diterpenoid metabolic processGO:0016101240.018
negative regulation of cell developmentGO:00107211690.018
negative regulation of cellular response to growth factor stimulusGO:0090288460.018
positive regulation of cell projection organizationGO:0031346950.018
regulation of transmembrane transportGO:00347621280.017
nuclear exportGO:0051168340.017
positive regulation of cell developmentGO:00107202370.017
microtubule based processGO:00070172360.017
cellular response to carbohydrate stimulusGO:0071322500.017
respiratory system developmentGO:00605411900.017
neural tube developmentGO:00219151600.017
actin cytoskeleton organizationGO:00300362200.017
mesonephros developmentGO:0001823970.017
regulation of cyclic nucleotide metabolic processGO:0030799400.017
epithelial tube morphogenesisGO:00605623030.017
terpenoid biosynthetic processGO:001611470.017
nucleoside triphosphate metabolic processGO:00091412300.017
positive regulation of dendritic spine developmentGO:0060999120.017
negative regulation of phosphorylationGO:00423261660.017
dephosphorylationGO:00163111290.017
response to steroid hormoneGO:0048545560.017
leukocyte differentiationGO:00025213420.017
regulation of cell cycleGO:00517262810.017
divalent inorganic cation transportGO:00725111780.017
positive regulation of cellular amine metabolic processGO:003324050.016
pancreas developmentGO:0031016570.016
sterol homeostasisGO:0055092450.016
mitotic nuclear divisionGO:0007067480.016
progesterone metabolic processGO:004244840.016
nuclear divisionGO:00002801580.016
response to organic cyclic compoundGO:00140701980.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.016
organic anion transportGO:00157111370.016
peptide metabolic processGO:0006518460.016
monocarboxylic acid metabolic processGO:00327871910.016
negative regulation of intracellular transportGO:0032387380.016
nuclear transportGO:00511691390.016
hepaticobiliary system developmentGO:0061008670.016
positive regulation of neuron projection developmentGO:0010976790.016
cyclic purine nucleotide metabolic processGO:0052652430.016
positive regulation of apoptotic processGO:00430652170.016
negative regulation of cell cycleGO:00457861230.016
midgut developmentGO:000749440.016
anion transmembrane transportGO:0098656710.016
transmission of nerve impulseGO:0019226760.015
glucose metabolic processGO:0006006920.015
small molecule catabolic processGO:0044282710.015
positive regulation of protein modification processGO:00314012990.015
amino acid betaine transportGO:001583830.015
single organism cell adhesionGO:00986021560.015
nephron epithelium developmentGO:0072009920.015
cellular response to molecule of bacterial originGO:0071219830.015
negative regulation of protein metabolic processGO:00512482820.015
sequestering of calcium ionGO:0051208180.015
response to extracellular stimulusGO:00099911270.015
organelle fissionGO:00482851700.015
regulation of neuron projection developmentGO:00109751690.015
sodium ion transportGO:0006814730.015
nitrogen compound transportGO:00717052710.015
purine nucleotide biosynthetic processGO:0006164650.015
energy derivation by oxidation of organic compoundsGO:0015980770.015
protein localization to nucleusGO:00345041210.015
divalent inorganic cation homeostasisGO:00725071380.015
cholesterol homeostasisGO:0042632440.015
regulation of purine nucleotide biosynthetic processGO:1900371340.015
dendrite developmentGO:00163581150.015
negative regulation of ion transportGO:0043271280.014
limb morphogenesisGO:00351081490.014
protein targetingGO:00066051430.014
ribonucleoside triphosphate catabolic processGO:00092031990.014
small gtpase mediated signal transductionGO:0007264970.014
striated muscle contractionGO:0006941450.014
negative regulation of calcium ion transmembrane transportGO:190317010.014
purine ribonucleotide catabolic processGO:00091542080.014
germ cell developmentGO:00072811850.014
cellular response to acid chemicalGO:0071229680.014
regulation of cellular amino acid metabolic processGO:000652150.014
cation transmembrane transportGO:00986552660.014
circadian rhythmGO:00076231140.014
negative regulation of phosphorus metabolic processGO:00105631840.014
regulation of apoptotic signaling pathwayGO:20012331970.014
amino acid transmembrane transportGO:0003333370.014
kidney epithelium developmentGO:00720731210.014
guanosine containing compound catabolic processGO:19010691440.014
determination of left right symmetryGO:0007368800.014
angiogenesisGO:00015252010.014
terpenoid metabolic processGO:0006721250.014
cellular response to abiotic stimulusGO:0071214560.014
rhythmic processGO:00485111740.014
pallium developmentGO:00215431200.014
cellular amino acid metabolic processGO:00065201030.014
response to phGO:0009268140.014
lipid transportGO:0006869980.014
skeletal system developmentGO:00015013560.014
cellular response to antibioticGO:007123640.014
purine ribonucleoside catabolic processGO:00461302050.014
pilomotor reflexGO:009719530.014
negative regulation of cellular protein metabolic processGO:00322692470.014
cognitionGO:00508901490.014
sensory organ morphogenesisGO:00905962420.013
negative regulation of growthGO:0045926990.013
positive regulation of bindingGO:0051099490.013
retinoid metabolic processGO:0001523240.013
mechanoreceptor differentiationGO:0042490670.013
response to peptideGO:19016521360.013
regulation of lymphocyte differentiationGO:00456191070.013
negative regulation of phosphate metabolic processGO:00459361840.013
protein importGO:00170381010.013
muscle cell differentiationGO:00426922610.013
organophosphate catabolic processGO:00464342320.013
multicellular organism growthGO:00352641610.013
nucleoside metabolic processGO:00091162460.013
maternal process involved in female pregnancyGO:0060135320.013
organelle localizationGO:00516401790.013
cellular metal ion homeostasisGO:00068751510.013
regulation of blood pressureGO:0008217930.013
9 cis retinoic acid biosynthetic processGO:004290450.013
detection of stimulusGO:0051606840.013
negative regulation of cellular amino acid metabolic processGO:004576300.013
cellular carbohydrate metabolic processGO:00442621190.013
development of primary sexual characteristicsGO:00451371430.013
regionalizationGO:00030023370.013
sequestering of metal ionGO:0051238190.013
purine ribonucleoside triphosphate catabolic processGO:00092071990.013
cellular response to oxidative stressGO:0034599760.013
positive regulation of neuron differentiationGO:00456661410.012
blastocyst developmentGO:0001824800.012
regulation of protein bindingGO:0043393600.012
epithelial cell proliferationGO:00506731740.012
establishment or maintenance of cell polarityGO:0007163860.012
glycerolipid metabolic processGO:00464861220.012
vitamin transportGO:0051180100.012
monocarboxylic acid transportGO:0015718440.012
cytokine productionGO:00018163190.012
neuron projection guidanceGO:00974851410.012
cellular response to growth factor stimulusGO:00713631970.012
regulation of cell substrate adhesionGO:0010810730.012
regulation of intracellular protein transportGO:0033157820.012
canonical wnt signaling pathwayGO:00600701300.012
extracellular matrix organizationGO:00301981470.012
inflammatory responseGO:00069542440.012
regulation of ion transmembrane transporter activityGO:0032412540.012
purine nucleotide catabolic processGO:00061952110.012
ribonucleoside triphosphate metabolic processGO:00091992200.012
male sex differentiationGO:00466611090.012
amide transportGO:00428861380.012
digestionGO:0007586400.012
glucose homeostasisGO:00425931280.012
positive regulation of cellular amino acid metabolic processGO:004576430.012
protein catabolic processGO:00301632210.012
detection of chemical stimulus involved in sensory perceptionGO:0050907100.012
gtp catabolic processGO:00061841430.012
phospholipid metabolic processGO:0006644870.012
embryonic heart tube developmentGO:0035050650.012
embryonic organ morphogenesisGO:00485622760.012
cellular glucose homeostasisGO:0001678520.011
sensory perception of chemical stimulusGO:0007606510.011
cellular lipid metabolic processGO:00442553230.011
polysaccharide metabolic processGO:0005976390.011
exocytosisGO:00068871210.011
mrna metabolic processGO:0016071840.011
wnt signaling pathwayGO:00160551880.011
positive regulation of cell deathGO:00109422240.011
positive regulation of heart rate by epinephrine norepinephrineGO:000199640.011
oviduct developmentGO:006006630.011
heart processGO:0003015940.011
homeostasis of number of cellsGO:00488722100.011
cytosolic calcium ion homeostasisGO:0051480700.011
regulation of carbohydrate metabolic processGO:0006109750.011
oocyte constructionGO:000730820.011
ras protein signal transductionGO:0007265770.011
cell cycle arrestGO:0007050370.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.011
central nervous system neuron differentiationGO:00219531620.011
photoreceptor cell developmentGO:0042461400.011
cellular response to acidic phGO:007146840.011
cellular response to lipopolysaccharideGO:0071222770.011
response to peptide hormoneGO:00434341270.011
skeletal muscle organ developmentGO:00605381630.011
regulation of camp biosynthetic processGO:0030817250.011
lung developmentGO:00303241640.011
epithelial cell developmentGO:00020641590.011
regulation of neurotransmitter levelsGO:0001505870.011
regulation of cyclic nucleotide biosynthetic processGO:0030802310.011
nucleoside phosphate catabolic processGO:19012922220.011
regulation of ras protein signal transductionGO:00465781140.011
memoryGO:0007613580.011
transepithelial chloride transportGO:003032140.011
protein import into nucleusGO:0006606950.011
calcium independent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633840.011
peptidyl amino acid modificationGO:00181933360.011
neurotransmitter transportGO:0006836760.011
photoreceptor cell differentiationGO:0046530520.011
purine nucleoside catabolic processGO:00061522050.011
positive regulation of fatty acid oxidationGO:004632140.011
potassium ion transportGO:0006813520.011
vitamin transmembrane transportGO:003546140.010
kidney morphogenesisGO:0060993830.010
inner ear morphogenesisGO:00424721010.010
response to oxidative stressGO:00069791230.010
nucleocytoplasmic transportGO:00069131390.010
regulation of toll like receptor 2 signaling pathwayGO:003413530.010
smoothened signaling pathwayGO:00072241050.010
guanosine containing compound metabolic processGO:19010681440.010
response to corticosteroidGO:0031960200.010
gtp metabolic processGO:00460391440.010
regulation of calcium ion transportGO:0051924690.010
regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activityGO:003158520.010
embryonic digit morphogenesisGO:0042733560.010
response to nutrient levelsGO:00316671090.010
regulation of generation of precursor metabolites and energyGO:0043467380.010
regulation of circadian sleep wake cycle sleepGO:004518730.010
adult behaviorGO:00305341350.010
regulation of cell adhesionGO:00301551540.010
response to monosaccharideGO:0034284670.010
cellular response to organonitrogen compoundGO:00714171450.010
uronic acid metabolic processGO:000606320.010
regulation of synaptic growth at neuromuscular junctionGO:000858240.010
positive regulation of protein kinase activityGO:00458601440.010
transition metal ion homeostasisGO:0055076540.010
response to osmotic stressGO:0006970210.010
lymphocyte differentiationGO:00300982420.010

Pkhd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.034
diabetes mellitusDOID:935100.018
glucose metabolism diseaseDOID:419400.018
carbohydrate metabolism diseaseDOID:005001300.018
acquired metabolic diseaseDOID:006015800.018
inherited metabolic disorderDOID:65500.017
disease of cellular proliferationDOID:1456600.017
steroid inherited metabolic disorderDOID:170100.014
lipid metabolism disorderDOID:314600.014
cancerDOID:16200.014
organ system cancerDOID:005068600.014
sensory system diseaseDOID:005015500.014
nervous system diseaseDOID:86300.014
disease of anatomical entityDOID:700.014
type 2 diabetes mellitusDOID:935200.013
cardiovascular system diseaseDOID:128700.012