Mus musculus

0 known processes

L2hgdh

L-2-hydroxyglutarate dehydrogenase

(Aliases: MGC28775,BC016226)

L2hgdh biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201030.079
mitochondrion organizationGO:00070051340.057
transmembrane transportGO:00550854120.057
organic cyclic compound catabolic processGO:19013612950.056
cellular nitrogen compound catabolic processGO:00442702800.055
heterocycle catabolic processGO:00467002800.054
nucleobase containing small molecule metabolic processGO:00550863520.050
aromatic compound catabolic processGO:00194392860.047
cellular ketone metabolic processGO:0042180840.039
cellular amine metabolic processGO:0044106440.039
glycosyl compound metabolic processGO:19016572460.037
intracellular protein transportGO:00068862040.037
amine metabolic processGO:0009308450.036
purine ribonucleotide metabolic processGO:00091502900.035
macromolecule catabolic processGO:00090572810.034
protein localization to organelleGO:00333651850.032
translationGO:0006412930.030
posttranscriptional regulation of gene expressionGO:00106081550.029
regulation of cellular amino acid metabolic processGO:000652150.029
regulation of cellular amine metabolic processGO:0033238200.028
regulation of cellular ketone metabolic processGO:0010565660.028
nucleoside metabolic processGO:00091162460.028
male gamete generationGO:00482322850.027
regulation of organelle organizationGO:00330432890.027
ion transmembrane transportGO:00342203610.027
purine nucleoside metabolic processGO:00422782410.027
positive regulation of cellular amine metabolic processGO:003324050.027
cation transportGO:00068123990.027
organonitrogen compound biosynthetic processGO:19015661920.026
cellular macromolecule catabolic processGO:00442652060.026
response to oxidative stressGO:00069791230.026
nucleoside phosphate metabolic processGO:00067533380.026
positive regulation of cellular amino acid metabolic processGO:004576430.026
purine ribonucleoside metabolic processGO:00461282410.025
regulation of cellular catabolic processGO:00313292420.025
membrane organizationGO:00610242450.025
oxidation reduction processGO:00551143420.024
cytoplasmic transportGO:00164822340.024
apoptotic signaling pathwayGO:00971903060.024
organonitrogen compound catabolic processGO:19015652640.024
regulation of cell activationGO:00508652890.024
cellular amino acid catabolic processGO:0009063250.024
purine containing compound metabolic processGO:00725213110.024
ribonucleotide metabolic processGO:00092592910.023
cellular homeostasisGO:00197252400.023
small gtpase mediated signal transductionGO:0007264970.023
nucleotide metabolic processGO:00091173320.022
ribonucleoside metabolic processGO:00091192450.022
mitochondrial translationGO:003254340.021
alpha amino acid metabolic processGO:1901605590.021
response to organonitrogen compoundGO:00102432460.021
ribonucleotide catabolic processGO:00092612080.021
ribose phosphate metabolic processGO:00196932910.021
dna metabolic processGO:00062593030.021
establishment of protein localization to organelleGO:00725941180.021
cell type specific apoptotic processGO:00972852680.020
spermatogenesisGO:00072832840.019
cation transmembrane transportGO:00986552660.019
protein catabolic processGO:00301632210.019
ribonucleoside triphosphate metabolic processGO:00091992200.019
organophosphate catabolic processGO:00464342320.019
purine nucleoside triphosphate metabolic processGO:00091442260.019
endomembrane system organizationGO:00102561470.018
rho protein signal transductionGO:0007266320.018
purine nucleoside catabolic processGO:00061522050.018
cofactor metabolic processGO:0051186800.018
ras protein signal transductionGO:0007265770.018
action potentialGO:0001508780.018
cellular protein complex assemblyGO:00436231160.018
purine nucleotide metabolic processGO:00061633020.018
multicellular organismal homeostasisGO:00488711640.018
protein maturationGO:00516041760.018
nitrogen compound transportGO:00717052710.018
peptidyl amino acid modificationGO:00181933360.017
regulation of mitochondrion organizationGO:0010821270.017
anion transportGO:00068201770.017
protein targetingGO:00066051430.017
generation of precursor metabolites and energyGO:00060911030.017
carbohydrate derivative catabolic processGO:19011362310.017
protein processingGO:00164851630.017
leukocyte differentiationGO:00025213420.017
regulation of membrane potentialGO:00423911920.017
neuronal action potentialGO:0019228540.016
negative regulation of intracellular signal transductionGO:19025321670.016
multicellular organismal signalingGO:0035637910.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.016
regulation of protein localizationGO:00328802310.016
epithelial tube morphogenesisGO:00605623030.016
inorganic cation transmembrane transportGO:00986622070.016
immune effector processGO:00022523210.016
transmission of nerve impulseGO:0019226760.016
regulation of lymphocyte activationGO:00512492400.016
cellular chemical homeostasisGO:00550822150.016
coenzyme metabolic processGO:0006732520.016
homeostasis of number of cellsGO:00488722100.015
intrinsic apoptotic signaling pathwayGO:00971931320.015
purine containing compound catabolic processGO:00725232130.015
regulation of cellular response to stressGO:00801351590.015
purine nucleoside triphosphate catabolic processGO:00091462030.015
regulation of cytokine productionGO:00018172660.015
purine ribonucleoside catabolic processGO:00461302050.015
purine ribonucleoside triphosphate metabolic processGO:00092052200.015
regulation of defense responseGO:00313472330.015
locomotory behaviorGO:00076261950.015
b cell activationGO:00421131610.015
nucleoside triphosphate catabolic processGO:00091432050.015
sensory perceptionGO:00076002450.015
inorganic ion transmembrane transportGO:00986602340.015
protein importGO:00170381010.015
cation homeostasisGO:00550802120.015
t cell activationGO:00421102890.014
regulation of translationGO:0006417710.014
negative regulation of molecular functionGO:00440922580.014
response to organic cyclic compoundGO:00140701980.014
metal ion homeostasisGO:00550651890.014
organic hydroxy compound metabolic processGO:19016152030.014
germ cell developmentGO:00072811850.014
purine nucleotide catabolic processGO:00061952110.014
nucleocytoplasmic transportGO:00069131390.014
negative regulation of immune system processGO:00026832090.014
nucleoside phosphate catabolic processGO:19012922220.014
regulation of t cell activationGO:00508631700.014
negative regulation of apoptotic signaling pathwayGO:20012341040.014
glycosyl compound catabolic processGO:19016582060.014
regulation of hydrolase activityGO:00513362460.014
cellular lipid metabolic processGO:00442553230.014
spermatid differentiationGO:00485151150.014
multicellular organism growthGO:00352641610.013
muscle tissue developmentGO:00605373080.013
regulation of homeostatic processGO:00328441820.013
negative regulation of cellular component organizationGO:00511291940.013
skeletal system developmentGO:00015013560.013
sulfur compound metabolic processGO:00067901000.013
protein modification by small protein conjugation or removalGO:00706472070.013
positive regulation of lymphocyte activationGO:00512511400.013
nucleoside catabolic processGO:00091642060.013
tissue homeostasisGO:00018941150.013
regulation of cellular component biogenesisGO:00440871810.013
renal system developmentGO:00720012250.013
positive regulation of cell deathGO:00109422240.013
nucleotide catabolic processGO:00091662170.013
regulation of ion transportGO:00432692150.013
cytokine productionGO:00018163190.013
negative regulation of protein metabolic processGO:00512482820.013
ribonucleoside catabolic processGO:00424542060.013
purine nucleoside monophosphate metabolic processGO:0009126810.013
lymphocyte differentiationGO:00300982420.013
camera type eye developmentGO:00430102660.013
nucleoside triphosphate metabolic processGO:00091412300.013
negative regulation of cellular protein metabolic processGO:00322692470.013
carboxylic acid biosynthetic processGO:0046394860.012
myeloid cell differentiationGO:00300992330.012
regulation of transmembrane transportGO:00347621280.012
carbohydrate derivative biosynthetic processGO:19011371830.012
gland developmentGO:00487323300.012
purine ribonucleotide catabolic processGO:00091542080.012
negative regulation of phosphate metabolic processGO:00459361840.012
regulation of anatomical structure sizeGO:00900661780.012
small molecule catabolic processGO:0044282710.012
response to endoplasmic reticulum stressGO:0034976530.012
defecationGO:003042110.012
sulfur compound biosynthetic processGO:0044272370.012
organic acid biosynthetic processGO:0016053860.012
regulation of kinase activityGO:00435492490.012
striated muscle tissue developmentGO:00147062930.012
regulation of ion transmembrane transportGO:00347651190.012
negative regulation of phosphorus metabolic processGO:00105631840.012
cellular response to organonitrogen compoundGO:00714171450.012
urogenital system developmentGO:00016552610.012
small molecule biosynthetic processGO:00442831320.012
spermatid developmentGO:00072861080.012
lymphocyte proliferationGO:00466511640.012
ribonucleoside monophosphate metabolic processGO:0009161800.012
divalent inorganic cation transportGO:00725111780.012
response to extracellular stimulusGO:00099911270.011
innate immune responseGO:00450871570.011
neuron apoptotic processGO:00514021420.011
regulation of leukocyte differentiationGO:19021051590.011
coenzyme biosynthetic processGO:0009108230.011
organic acid transportGO:00158491010.011
divalent metal ion transportGO:00708381720.011
negative regulation of cell proliferationGO:00082852960.011
male anatomical structure morphogenesisGO:009059840.011
positive regulation of programmed cell deathGO:00430682180.011
adult behaviorGO:00305341350.011
positive regulation of hydrolase activityGO:00513451480.011
lymphocyte mediated immunityGO:00024491390.011
ribonucleoside triphosphate catabolic processGO:00092031990.011
positive regulation of protein modification processGO:00314012990.011
nucleoside monophosphate metabolic processGO:0009123850.011
cellular response to growth factor stimulusGO:00713631970.011
purine ribonucleoside monophosphate metabolic processGO:0009167800.011
regulation of hormone levelsGO:00108172110.011
anatomical structure homeostasisGO:00602491450.011
morphogenesis of embryonic epitheliumGO:00163311590.011
leukocyte mediated immunityGO:00024431740.011
cell maturationGO:00484691270.011
carboxylic acid catabolic processGO:0046395510.011
regulation of apoptotic signaling pathwayGO:20012331970.011
lipid biosynthetic processGO:00086101790.011
response to nutrient levelsGO:00316671090.010
response to inorganic substanceGO:0010035960.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.010
cell adhesionGO:00071553290.010
cellular ion homeostasisGO:00068731650.010
reactive oxygen species metabolic processGO:0072593840.010
cellular response to hormone stimulusGO:00328701500.010
positive regulation of cell developmentGO:00107202370.010
cellular modified amino acid metabolic processGO:0006575630.010
carbohydrate homeostasisGO:00335001280.010
regulation of purine nucleotide metabolic processGO:19005421690.010

L2hgdh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
amino acid metabolic disorderDOID:925200.052
inherited metabolic disorderDOID:65500.052
disease of metabolismDOID:001466700.052
disease of anatomical entityDOID:700.031
nervous system diseaseDOID:86300.031
immune system diseaseDOID:291400.018
central nervous system diseaseDOID:33100.014
neurodegenerative diseaseDOID:128900.014
disease of cellular proliferationDOID:1456600.014
musculoskeletal system diseaseDOID:1700.013
cancerDOID:16200.012
organ system cancerDOID:005068600.012
hematopoietic system diseaseDOID:7400.012