Mus musculus

0 known processes

Plekhm2

pleckstrin homology domain containing, family M (with RUN domain) member 2

(Aliases: mKIAA0842,AI854247,2310034J19Rik)

Plekhm2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
guanosine containing compound metabolic processGO:19010681440.172
positive regulation of gtp catabolic processGO:0033126850.119
purine containing compound catabolic processGO:00725232130.117
carbohydrate derivative catabolic processGO:19011362310.115
ras protein signal transductionGO:0007265770.114
regulation of gtp catabolic processGO:00331241130.111
purine nucleotide catabolic processGO:00061952110.106
small gtpase mediated signal transductionGO:0007264970.105
nucleotide catabolic processGO:00091662170.102
guanosine containing compound catabolic processGO:19010691440.101
heterocycle catabolic processGO:00467002800.098
regulation of nucleoside metabolic processGO:00091181300.095
nucleotide metabolic processGO:00091173320.095
organonitrogen compound catabolic processGO:19015652640.093
ribonucleotide catabolic processGO:00092612080.091
purine ribonucleoside triphosphate catabolic processGO:00092071990.091
nucleoside phosphate metabolic processGO:00067533380.087
transmembrane transportGO:00550854120.087
organophosphate catabolic processGO:00464342320.085
ribonucleoside triphosphate catabolic processGO:00092031990.085
cellular ketone metabolic processGO:0042180840.082
regulation of nucleotide metabolic processGO:00061401690.082
regulation of ras gtpase activityGO:0032318880.081
regulation of purine nucleotide catabolic processGO:00331211220.080
purine ribonucleotide catabolic processGO:00091542080.079
nucleoside phosphate catabolic processGO:19012922220.078
purine ribonucleoside triphosphate metabolic processGO:00092052200.078
ion transmembrane transportGO:00342203610.078
purine nucleotide metabolic processGO:00061633020.077
positive regulation of nucleotide catabolic processGO:0030813880.076
ribonucleotide metabolic processGO:00092592910.076
glycosyl compound catabolic processGO:19016582060.076
purine nucleoside catabolic processGO:00061522050.074
nucleobase containing small molecule metabolic processGO:00550863520.072
regulation of purine nucleotide metabolic processGO:19005421690.072
regulation of cellular catabolic processGO:00313292420.069
gtp metabolic processGO:00460391440.068
gtp catabolic processGO:00061841430.068
amine metabolic processGO:0009308450.068
purine containing compound metabolic processGO:00725213110.067
glycosyl compound metabolic processGO:19016572460.066
regulation of hydrolase activityGO:00513362460.066
ribonucleoside triphosphate metabolic processGO:00091992200.065
organic cyclic compound catabolic processGO:19013612950.063
positive regulation of ras gtpase activityGO:0032320650.063
cation transmembrane transportGO:00986552660.063
cellular amino acid metabolic processGO:00065201030.062
positive regulation of nucleoside metabolic processGO:0045979910.060
positive regulation of purine nucleotide metabolic processGO:19005441140.060
cation transportGO:00068123990.059
nucleoside triphosphate metabolic processGO:00091412300.059
positive regulation of gtpase activityGO:0043547850.059
regulation of nucleotide catabolic processGO:00308111220.059
purine ribonucleotide metabolic processGO:00091502900.058
regulation of ras protein signal transductionGO:00465781140.058
cellular nitrogen compound catabolic processGO:00442702800.057
purine nucleoside triphosphate metabolic processGO:00091442260.057
positive regulation of purine nucleotide catabolic processGO:0033123880.057
nucleoside metabolic processGO:00091162460.057
purine nucleoside triphosphate catabolic processGO:00091462030.056
ribonucleoside catabolic processGO:00424542060.055
inorganic cation transmembrane transportGO:00986622070.055
purine nucleoside metabolic processGO:00422782410.052
anion transportGO:00068201770.051
ribonucleoside metabolic processGO:00091192450.051
inorganic ion transmembrane transportGO:00986602340.051
positive regulation of hydrolase activityGO:00513451480.048
cellular amine metabolic processGO:0044106440.047
positive regulation of cellular catabolic processGO:00313311480.046
muscle cell differentiationGO:00426922610.046
regulation of cellular ketone metabolic processGO:0010565660.046
purine ribonucleoside catabolic processGO:00461302050.046
purine ribonucleoside metabolic processGO:00461282410.045
nucleoside catabolic processGO:00091642060.044
ribose phosphate metabolic processGO:00196932910.044
membrane organizationGO:00610242450.044
aromatic compound catabolic processGO:00194392860.044
rho protein signal transductionGO:0007266320.043
positive regulation of nucleotide metabolic processGO:00459811140.043
nucleoside triphosphate catabolic processGO:00091432050.041
protein modification by small protein conjugation or removalGO:00706472070.041
regulation of cellular amino acid metabolic processGO:000652150.037
peptidyl amino acid modificationGO:00181933360.036
regulation of cellular amine metabolic processGO:0033238200.036
asymmetric stem cell divisionGO:009872230.034
negative regulation of cellular amine metabolic processGO:003323910.034
synaptic transmissionGO:00072683290.033
regulation of transferase activityGO:00513382630.033
protein ubiquitinationGO:00165671710.032
regulation of cell cycleGO:00517262810.031
protein modification by small protein conjugationGO:00324461870.031
nitrogen compound transportGO:00717052710.029
cellular lipid metabolic processGO:00442553230.029
neurotransmitter transportGO:0006836760.029
regulation of system processGO:00440572000.029
macromolecule catabolic processGO:00090572810.029
apoptotic signaling pathwayGO:00971903060.028
organic anion transportGO:00157111370.028
organic acid transportGO:00158491010.028
leukocyte differentiationGO:00025213420.027
t cell activationGO:00421102890.027
regulation of vesicle mediated transportGO:00606271390.027
axonogenesisGO:00074092740.027
negative regulation of cellular amino acid metabolic processGO:004576300.027
sensory organ morphogenesisGO:00905962420.026
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.026
cellular response to dna damage stimulusGO:00069742070.026
positive regulation of cellular amino acid metabolic processGO:004576430.026
regulation of kinase activityGO:00435492490.025
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.024
regulation of membrane potentialGO:00423911920.024
negative regulation of molecular functionGO:00440922580.024
positive regulation of cellular amine metabolic processGO:003324050.024
negative regulation of cell proliferationGO:00082852960.024
response to molecule of bacterial originGO:00022371430.023
regulation of cell projection organizationGO:00313442060.023
response to lipopolysaccharideGO:00324961280.023
intracellular protein transportGO:00068862040.023
multicellular organismal signalingGO:0035637910.023
immune effector processGO:00022523210.023
multicellular organism growthGO:00352641610.023
regulation of protein localizationGO:00328802310.023
positive regulation of protein modification processGO:00314012990.023
oxidation reduction processGO:00551143420.023
negative regulation of cellular protein metabolic processGO:00322692470.022
muscle system processGO:00030121410.022
carboxylic acid transportGO:00469421000.022
sodium ion transportGO:0006814730.022
muscle tissue developmentGO:00605373080.022
glycerolipid metabolic processGO:00464861220.022
regulation of organelle organizationGO:00330432890.022
positive regulation of neuron differentiationGO:00456661410.021
organelle localizationGO:00516401790.021
mapk cascadeGO:00001652810.021
actin cytoskeleton organizationGO:00300362200.021
circulatory system processGO:00030131970.021
regulation of neurotransmitter levelsGO:0001505870.021
positive regulation of nervous system developmentGO:00519622210.021
regulation of cellular component biogenesisGO:00440871810.021
regulation of neuron projection developmentGO:00109751690.021
male gamete generationGO:00482322850.021
modification dependent protein catabolic processGO:00199411330.020
regulation of protein kinase activityGO:00458592320.020
protein localization to organelleGO:00333651850.020
dephosphorylationGO:00163111290.020
myeloid cell differentiationGO:00300992330.020
protein catabolic processGO:00301632210.020
microtubule based processGO:00070172360.020
positive regulation of cell developmentGO:00107202370.019
skeletal system developmentGO:00015013560.019
microtubule cytoskeleton organizationGO:00002261570.019
regulation of apoptotic signaling pathwayGO:20012331970.019
regulation of lymphocyte activationGO:00512492400.019
neuron deathGO:00709971540.019
sodium ion transmembrane transportGO:0035725490.019
rab protein signal transductionGO:003248210.019
compound eye developmentGO:004874910.018
regulation of secretionGO:00510462740.018
negative regulation of protein modification processGO:00314001630.018
regulation of t cell activationGO:00508631700.018
regulation of secretion by cellGO:19035302490.018
regulation of neuron differentiationGO:00456642810.018
neuron apoptotic processGO:00514021420.018
protein maturationGO:00516041760.018
cellular homeostasisGO:00197252400.018
epithelial cell developmentGO:00020641590.018
cellular macromolecule catabolic processGO:00442652060.017
cellular chemical homeostasisGO:00550822150.017
striated muscle tissue developmentGO:00147062930.017
cell adhesionGO:00071553290.017
organic hydroxy compound metabolic processGO:19016152030.017
regulation of ion transportGO:00432692150.017
regulation of muscle system processGO:0090257800.016
regulation of ion transmembrane transportGO:00347651190.016
regulation of neuron apoptotic processGO:00435231220.016
negative regulation of protein phosphorylationGO:00019331260.016
cation homeostasisGO:00550802120.016
regulation of synaptic growth at neuromuscular junctionGO:000858240.016
response to light stimulusGO:00094161350.016
regulation of cell morphogenesis involved in differentiationGO:00107691510.016
positive regulation of apoptotic signaling pathwayGO:2001235950.016
positive regulation of rho gtpase activityGO:0032321410.016
cell type specific apoptotic processGO:00972852680.016
cellular protein catabolic processGO:00442571550.016
cellular response to cytokine stimulusGO:00713451890.016
blood circulationGO:00080151950.016
maintenance of locationGO:0051235890.016
cellular response to lipopolysaccharideGO:0071222770.015
regulation of mapk cascadeGO:00434082480.015
positive regulation of protein phosphorylationGO:00019342420.015
asymmetric neuroblast divisionGO:005505910.015
positive regulation of programmed cell deathGO:00430682180.015
negative regulation of phosphorus metabolic processGO:00105631840.015
response to inorganic substanceGO:0010035960.015
negative regulation of cell activationGO:00508661110.015
sensory perceptionGO:00076002450.015
bone developmentGO:00603481200.015
cellular ion homeostasisGO:00068731650.015
regulation of transmembrane transportGO:00347621280.015
carbohydrate metabolic processGO:00059752300.015
monocarboxylic acid metabolic processGO:00327871910.015
regulation of cytoskeleton organizationGO:00514931220.015
cellular response to molecule of bacterial originGO:0071219830.015
proteolysis involved in cellular protein catabolic processGO:00516031470.015
negative regulation of phosphate metabolic processGO:00459361840.015
chromatin organizationGO:00063252060.015
ubiquitin dependent protein catabolic processGO:00065111290.015
forebrain developmentGO:00309003020.015
response to radiationGO:00093141650.015
engulfment of apoptotic cellGO:004365230.014
chromatin modificationGO:00165681870.014
regulation of rho protein signal transductionGO:0035023710.014
regulation of cell motilityGO:20001452360.014
protein processingGO:00164851630.014
establishment of vesicle localizationGO:0051650810.014
regulation of sequence specific dna binding transcription factor activityGO:00510901060.014
alpha beta t cell activationGO:0046631910.014
endocytosisGO:00068971680.014
embryonic epithelial tube formationGO:00018381300.014
gene silencingGO:0016458380.014
divalent inorganic cation transportGO:00725111780.014
reactive oxygen species metabolic processGO:0072593840.014
organonitrogen compound biosynthetic processGO:19015661920.014
neuron migrationGO:00017641220.014
lymphocyte differentiationGO:00300982420.014
g protein coupled receptor signaling pathwayGO:00071862430.014
cell divisionGO:00513011200.014
lipid localizationGO:00108761260.014
lipid biosynthetic processGO:00086101790.014
glycerophospholipid metabolic processGO:0006650710.014
epithelial cell proliferationGO:00506731740.013
limb developmentGO:00601731660.013
positive regulation of cell deathGO:00109422240.013
stem cell proliferationGO:00720891170.013
cellular response to organonitrogen compoundGO:00714171450.013
reactive oxygen species biosynthetic processGO:190340980.013
lipid modificationGO:0030258650.013
regulation of cellular response to stressGO:00801351590.013
developmental maturationGO:00217001930.013
covalent chromatin modificationGO:00165691630.013
transmission of nerve impulseGO:0019226760.013
modification dependent macromolecule catabolic processGO:00436321330.013
calcium ion transmembrane transportGO:0070588850.013
blood vessel morphogenesisGO:00485142850.013
exocytosisGO:00068871210.013
gland developmentGO:00487323300.013
myosin filament assemblyGO:003103420.013
appendage developmentGO:00487361660.013
cellular response to biotic stimulusGO:0071216920.013
regulation of cell activationGO:00508652890.013
positive regulation of transferase activityGO:00513471670.013
negative regulation of phosphorylationGO:00423261660.013
posttranscriptional regulation of gene expressionGO:00106081550.012
cellular protein complex assemblyGO:00436231160.012
response to organic cyclic compoundGO:00140701980.012
pallium developmentGO:00215431200.012
cell activation involved in immune responseGO:00022631260.012
locomotory behaviorGO:00076261950.012
protein targetingGO:00066051430.012
positive regulation of protein kinase activityGO:00458601440.012
skin developmentGO:00435882200.012
lung developmentGO:00303241640.012
spermatogenesisGO:00072832840.012
phospholipid metabolic processGO:0006644870.012
regulation of protein catabolic processGO:00421761080.012
chemotaxisGO:00069352470.012
establishment of organelle localizationGO:00516561220.012
lipid transportGO:0006869980.012
positive regulation of apoptotic processGO:00430652170.012
neural tube formationGO:00018411080.012
action potentialGO:0001508780.012
t cell proliferationGO:00420981200.012
neurotransmitter secretionGO:0007269620.012
response to organonitrogen compoundGO:00102432460.012
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.012
cellular response to lipidGO:00713961450.012
camera type eye developmentGO:00430102660.012
cellular carbohydrate metabolic processGO:00442621190.012
retina development in camera type eyeGO:00600411190.012
sensory system developmentGO:004888030.012
cellular lipid catabolic processGO:0044242520.012
dna metabolic processGO:00062593030.012
carbohydrate derivative biosynthetic processGO:19011371830.012
regulation of hormone levelsGO:00108172110.012
respiratory system developmentGO:00605411900.012
negative regulation of nervous system developmentGO:00519611560.011
negative regulation of intracellular signal transductionGO:19025321670.011
epidermis developmentGO:00085441870.011
glucose homeostasisGO:00425931280.011
negative regulation of protein metabolic processGO:00512482820.011
photoreceptor cell differentiationGO:0046530520.011
fat cell differentiationGO:00454441600.011
defecationGO:003042110.011
angiogenesisGO:00015252010.011
ossificationGO:00015032160.011
leukocyte mediated immunityGO:00024431740.011
regulation of neuron deathGO:19012141340.011
positive regulation of dna templated transcription elongationGO:003278620.011
telencephalon developmentGO:00215371860.011
regulation of anatomical structure sizeGO:00900661780.011
regulation of metal ion transportGO:00109591060.011
urogenital system developmentGO:00016552610.011
glucose metabolic processGO:0006006920.011
single organism cell adhesionGO:00986021560.011
dendrite developmentGO:00163581150.011
regulation of rho gtpase activityGO:0032319580.011
primary neural tube formationGO:0014020950.011
regulation of leukocyte differentiationGO:19021051590.011
endomembrane system organizationGO:00102561470.011
Human
tube closureGO:0060606910.011
organelle assemblyGO:00709251770.011
pharynx developmentGO:006046510.011
embryonic organ morphogenesisGO:00485622760.011
negative regulation of growthGO:0045926990.011
regulation of transporter activityGO:0032409570.011
histone modificationGO:00165701590.011
regulation of multi organism processGO:00439001110.011
potassium ion transportGO:0006813520.011
leukocyte activation involved in immune responseGO:00023661260.011
photoreceptor cell developmentGO:0042461400.011
lymphocyte proliferationGO:00466511640.011
regulation of endocytosisGO:0030100690.011
regulation of striated muscle cell differentiationGO:0051153810.011
regulation of cell cycle processGO:00105641600.011
neural tube closureGO:0001843900.011
metal ion homeostasisGO:00550651890.011
protein localization to membraneGO:00726571080.011
neural tube developmentGO:00219151600.011
establishment of synaptic vesicle localizationGO:0097480570.011
sequestering of metal ionGO:0051238190.011
stem cell differentiationGO:00488632680.010
leukocyte proliferationGO:00706611720.010
connective tissue developmentGO:00614481790.010
cytokine productionGO:00018163190.010
neuronal action potentialGO:0019228540.010
appendage morphogenesisGO:00351071490.010
negative regulation of t cell activationGO:0050868650.010
negative regulation of cellular component organizationGO:00511291940.010
vesicle localizationGO:0051648860.010
regulation of reactive oxygen species metabolic processGO:2000377400.010
proteasomal protein catabolic processGO:0010498980.010
peptidyl serine phosphorylationGO:0018105740.010
regulation of cell adhesionGO:00301551540.010
synaptic vesicle transportGO:0048489570.010
response to acid chemicalGO:00011011110.010
lateral inhibitionGO:004633110.010
synaptic vesicle localizationGO:0097479590.010
monocarboxylic acid transportGO:0015718440.010
response to growth factorGO:00708481980.010
regulation of protein serine threonine kinase activityGO:00719001570.010
epithelial tube formationGO:00721751300.010
neural precursor cell proliferationGO:00613511210.010

Plekhm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.033
nervous system diseaseDOID:86300.033
disease of metabolismDOID:001466700.027
central nervous system diseaseDOID:33100.019
musculoskeletal system diseaseDOID:1700.015
inherited metabolic disorderDOID:65500.013
acquired metabolic diseaseDOID:006015800.011