Mus musculus

52 known processes

Pclo

piccolo (presynaptic cytomatrix protein)

(Aliases: Acz,Pico,mKIAA0559)

Pclo biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
synaptic transmissionGO:00072683290.856
establishment of vesicle localizationGO:0051650810.586
regulation of neurotransmitter levelsGO:0001505870.507
synaptic vesicle localizationGO:0097479590.410
vesicle localizationGO:0051648860.341
regulation of membrane potentialGO:00423911920.288
regulation of neuron differentiationGO:00456642810.256
sensory perception of soundGO:0007605970.241
cellular protein complex assemblyGO:00436231160.234
membrane organizationGO:00610242450.201
transmembrane transportGO:00550854120.190
neurotransmitter secretionGO:0007269620.189
establishment of organelle localizationGO:00516561220.183
neurotransmitter transportGO:0006836760.166
regulation of postsynaptic membrane potentialGO:0060078480.165
nitrogen compound transportGO:00717052710.165
action potentialGO:0001508780.162
establishment of synaptic vesicle localizationGO:0097480570.152
gtp catabolic processGO:00061841430.151
adult behaviorGO:00305341350.147
regulation of neuron projection developmentGO:00109751690.141
central nervous system neuron differentiationGO:00219531620.139
g protein coupled receptor signaling pathwayGO:00071862430.136
purine ribonucleotide metabolic processGO:00091502900.133
nucleoside metabolic processGO:00091162460.126
purine nucleoside triphosphate metabolic processGO:00091442260.125
cation transmembrane transportGO:00986552660.125
anion transportGO:00068201770.125
positive regulation of programmed cell deathGO:00430682180.124
positive regulation of cell deathGO:00109422240.124
synaptic vesicle primingGO:001608280.122
guanosine containing compound metabolic processGO:19010681440.120
organic anion transportGO:00157111370.119
regulation of hydrolase activityGO:00513362460.118
organelle localizationGO:00516401790.116
dendrite developmentGO:00163581150.113
neuron migrationGO:00017641220.112
purine nucleotide metabolic processGO:00061633020.109
inorganic ion transmembrane transportGO:00986602340.109
purine ribonucleoside metabolic processGO:00461282410.105
regulation of neuronal synaptic plasticityGO:0048168300.103
synaptic vesicle transportGO:0048489570.102
synaptic transmission glutamatergicGO:0035249360.100
regulation of cell projection organizationGO:00313442060.098
organic cyclic compound catabolic processGO:19013612950.096
sensory perception of mechanical stimulusGO:00509541070.095
second messenger mediated signalingGO:0019932730.094
synaptic transmission cholinergicGO:000727170.093
guanosine containing compound catabolic processGO:19010691440.092
purine nucleoside metabolic processGO:00422782410.089
regulation of excitatory postsynaptic membrane potentialGO:0060079410.088
insulin secretionGO:0030073890.087
amide transportGO:00428861380.084
protein polymerizationGO:0051258570.081
regulation of secretionGO:00510462740.079
organonitrogen compound catabolic processGO:19015652640.079
cellular nitrogen compound catabolic processGO:00442702800.079
locomotory behaviorGO:00076261950.078
exocytosisGO:00068871210.077
nucleoside phosphate catabolic processGO:19012922220.077
regulation of protein localizationGO:00328802310.077
multicellular organismal signalingGO:0035637910.076
ribonucleoside metabolic processGO:00091192450.075
heterocycle catabolic processGO:00467002800.074
positive regulation of nucleoside metabolic processGO:0045979910.073
glycosyl compound metabolic processGO:19016572460.073
cell adhesionGO:00071553290.072
adult locomotory behaviorGO:0008344910.071
regulation of organelle organizationGO:00330432890.070
learning or memoryGO:00076111480.069
negative regulation of molecular functionGO:00440922580.069
purine containing compound catabolic processGO:00725232130.069
response to organonitrogen compoundGO:00102432460.067
ribonucleotide metabolic processGO:00092592910.067
regulation of exocytosisGO:0017157610.066
regulation of synaptic plasticityGO:0048167870.066
synapse organizationGO:00508081250.066
organophosphate catabolic processGO:00464342320.066
purine ribonucleotide catabolic processGO:00091542080.066
negative regulation of neuron differentiationGO:00456651010.065
small gtpase mediated signal transductionGO:0007264970.065
gtp metabolic processGO:00460391440.065
ribonucleoside triphosphate metabolic processGO:00091992200.065
regulation of gtp catabolic processGO:00331241130.064
neuron neuron synaptic transmissionGO:0007270690.064
calcium ion dependent exocytosisGO:0017156350.064
defecationGO:003042110.063
nucleoside triphosphate metabolic processGO:00091412300.063
purine ribonucleoside triphosphate metabolic processGO:00092052200.061
protein localization to juxtaparanode region of axonGO:007120540.061
aromatic compound catabolic processGO:00194392860.060
regulation of cellular component biogenesisGO:00440871810.060
ribonucleoside catabolic processGO:00424542060.059
regulation of purine nucleotide catabolic processGO:00331211220.059
membrane hyperpolarizationGO:0060081210.059
axonogenesisGO:00074092740.059
nucleobase containing small molecule metabolic processGO:00550863520.059
regulation of cellular amine metabolic processGO:0033238200.058
negative regulation of neuron projection developmentGO:0010977500.058
ras protein signal transductionGO:0007265770.058
positive regulation of hydrolase activityGO:00513451480.057
regulation of cellular catabolic processGO:00313292420.057
endomembrane system organizationGO:00102561470.057
establishment of glial blood brain barrierGO:006085720.057
purine nucleoside catabolic processGO:00061522050.056
nucleotide metabolic processGO:00091173320.055
regulation of ion transportGO:00432692150.055
cellular ketone metabolic processGO:0042180840.055
glycosyl compound catabolic processGO:19016582060.054
nucleoside phosphate metabolic processGO:00067533380.053
ribose phosphate metabolic processGO:00196932910.053
peptide transportGO:00158331330.053
lateral line system developmentGO:004892510.052
cell junction assemblyGO:0034329520.052
negative regulation of cell proliferationGO:00082852960.051
ribonucleotide catabolic processGO:00092612080.051
regulation of vesicle mediated transportGO:00606271390.050
regulation of cellular component sizeGO:00325351210.050
sensory perceptionGO:00076002450.049
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742400.049
cellular homeostasisGO:00197252400.049
negative regulation of cellular component organizationGO:00511291940.048
regulation of nucleotide catabolic processGO:00308111220.048
rap protein signal transductionGO:003248630.048
purine ribonucleoside triphosphate catabolic processGO:00092071990.047
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.047
purine nucleotide catabolic processGO:00061952110.047
cell type specific apoptotic processGO:00972852680.046
positive regulation of neuron differentiationGO:00456661410.045
purine ribonucleoside catabolic processGO:00461302050.045
hormone secretionGO:00468791280.045
regulation of hormone levelsGO:00108172110.045
carboxylic acid transportGO:00469421000.045
cation homeostasisGO:00550802120.045
sa node cell action potentialGO:008601540.044
negative regulation of nervous system developmentGO:00519611560.044
actin filament polymerizationGO:0030041440.044
regulation of mapk cascadeGO:00434082480.044
engulfment of apoptotic cellGO:004365230.043
spermatid developmentGO:00072861080.042
regulation of feeding behaviorGO:006025930.042
central nervous system neuron developmentGO:0021954670.042
carbohydrate derivative catabolic processGO:19011362310.042
ion transmembrane transportGO:00342203610.041
regulation of cell motilityGO:20001452360.041
plasma membrane organizationGO:0007009900.041
ear developmentGO:00435832000.041
olfactory learningGO:000835520.040
positive regulation of erk1 and erk2 cascadeGO:0070374470.040
neuromuscular processGO:0050905990.040
regulation of anatomical structure sizeGO:00900661780.039
mapk cascadeGO:00001652810.038
muscle system processGO:00030121410.038
positive regulation of nervous system developmentGO:00519622210.038
learningGO:0007612980.038
regulation of nucleoside metabolic processGO:00091181300.038
positive regulation of mapk cascadeGO:00434101700.038
male gamete generationGO:00482322850.037
cell junction organizationGO:0034330770.037
peptide secretionGO:00027901140.037
positive regulation of cell projection organizationGO:0031346950.037
positive regulation of neuron projection developmentGO:0010976790.037
cognitionGO:00508901490.037
muscle tissue developmentGO:00605373080.037
anatomical structure homeostasisGO:00602491450.037
positive regulation of cell developmentGO:00107202370.037
inorganic cation transmembrane transportGO:00986622070.036
neuronal action potentialGO:0019228540.036
gliogenesisGO:00420631410.036
spermatid differentiationGO:00485151150.036
nucleotide catabolic processGO:00091662170.036
fast calcium ion dependent exocytosis of neurotransmitterGO:009874610.035
fertilizationGO:00095661270.035
myelinationGO:0042552740.035
vesicle organizationGO:0016050600.035
regulation of protein complex assemblyGO:0043254830.035
cytokine productionGO:00018163190.035
cellular amino acid metabolic processGO:00065201030.034
regulation of cellular ketone metabolic processGO:0010565660.034
regulation of endocytosisGO:0030100690.034
ribonucleoside triphosphate catabolic processGO:00092031990.034
negative regulation of cell developmentGO:00107211690.034
dephosphorylationGO:00163111290.034
compound eye developmentGO:004874910.033
cellular lipid metabolic processGO:00442553230.033
protein processingGO:00164851630.033
peptide hormone secretionGO:00300721090.033
amino acid transmembrane transportGO:0003333370.032
organelle assemblyGO:00709251770.032
positive regulation of growthGO:00459271040.032
positive regulation of gtpase activityGO:0043547850.032
muscle contractionGO:00069361010.032
positive regulation of protein phosphorylationGO:00019342420.032
actin filament organizationGO:00070151130.031
positive regulation of nucleotide catabolic processGO:0030813880.031
calcium ion homeostasisGO:00550741270.031
positive regulation of gtp catabolic processGO:0033126850.030
striated muscle tissue developmentGO:00147062930.030
cation transportGO:00068123990.030
regulation of response to drugGO:200102320.030
regulation of transmembrane transportGO:00347621280.030
terminal button organizationGO:007255330.030
negative regulation of synaptic transmission glutamatergicGO:005196740.030
nucleoside triphosphate catabolic processGO:00091432050.030
nucleoside catabolic processGO:00091642060.029
synaptic vesicle exocytosisGO:0016079260.029
nerve developmentGO:0021675670.029
gland developmentGO:00487323300.028
sodium ion transportGO:0006814730.028
forebrain developmentGO:00309003020.028
regulation of purine nucleotide metabolic processGO:19005421690.028
hindbrain developmentGO:00309021280.028
purine nucleoside triphosphate catabolic processGO:00091462030.028
adult walking behaviorGO:0007628410.028
response to acid chemicalGO:00011011110.028
inner ear receptor cell developmentGO:0060119390.028
circadian rhythmGO:00076231140.028
regulation of secretion by cellGO:19035302490.028
erk1 and erk2 cascadeGO:0070371770.027
glial cell differentiationGO:00100011310.027
circulatory system processGO:00030131970.027
cellular response to organonitrogen compoundGO:00714171450.027
purine containing compound metabolic processGO:00725213110.027
regulation of neurotransmitter secretionGO:0046928290.026
camp mediated signalingGO:0019933150.026
positive regulation of rap gtpase activityGO:003285430.026
camera type eye developmentGO:00430102660.026
negative regulation of phosphate metabolic processGO:00459361840.026
organic acid transportGO:00158491010.025
protein localization to membraneGO:00726571080.025
nerve maturationGO:002168210.025
regulation of establishment of protein localizationGO:00702011810.025
positive regulation of cellular catabolic processGO:00313311480.025
synapse assemblyGO:0007416560.025
regulation of ion transmembrane transportGO:00347651190.025
sensory organ morphogenesisGO:00905962420.025
spermatogenesisGO:00072832840.025
protein maturationGO:00516041760.025
microtubule based processGO:00070172360.024
cell cell junction organizationGO:0045216720.024
cellular chemical homeostasisGO:00550822150.024
phospholipid dephosphorylationGO:004683960.024
endocytosisGO:00068971680.024
wnt signaling pathwayGO:00160551880.024
response to extracellular stimulusGO:00099911270.024
neuron deathGO:00709971540.024
regulation of synaptic transmission glutamatergicGO:0051966190.024
mitotic cytokinesisGO:000028140.023
response to histamineGO:003477610.023
response to organic cyclic compoundGO:00140701980.023
positive regulation of purine nucleotide catabolic processGO:0033123880.023
calcium ion dependent exocytosis of neurotransmitterGO:004879170.023
regulation of transferase activityGO:00513382630.023
regulation of kinase activityGO:00435492490.023
gonad morphogenesisGO:003526210.023
positive regulation of protein kinase activityGO:00458601440.023
myotube differentiationGO:00149021050.022
homophilic cell adhesion via plasma membrane adhesion moleculesGO:0007156180.022
cell divisionGO:00513011200.022
regulation of actin filament based processGO:0032970990.022
multicellular organism growthGO:00352641610.021
regulation of cellular amino acid metabolic processGO:000652150.021
positive regulation of organelle organizationGO:00106381280.021
positive regulation of protein modification processGO:00314012990.021
actin filament based movementGO:0030048230.021
sensory perception of light stimulusGO:0050953540.021
positive regulation of cellular component biogenesisGO:0044089940.021
regulation of system processGO:00440572000.021
regulation of ras protein signal transductionGO:00465781140.021
positive regulation of adenosine receptor signaling pathwayGO:006016810.021
skin developmentGO:00435882200.021
positive regulation of apoptotic processGO:00430652170.020
regulation of neuron migrationGO:2001222220.020
regulation of ras gtpase activityGO:0032318880.020
microtubule cytoskeleton organizationGO:00002261570.020
rho protein signal transductionGO:0007266320.020
regulation of nucleotide metabolic processGO:00061401690.020
regulation of n methyl d aspartate selective glutamate receptor activityGO:2000310100.020
regulation of cytoskeleton organizationGO:00514931220.020
neuropeptide signaling pathwayGO:0007218190.020
membrane depolarizationGO:0051899640.019
positive regulation of cellular amino acid metabolic processGO:004576430.019
single organism cell adhesionGO:00986021560.019
multicellular organismal response to stressGO:0033555620.019
cerebellum developmentGO:0021549770.019
negative regulation of dendrite developmentGO:200017190.019
inorganic anion transportGO:0015698430.019
chloride transportGO:0006821320.019
retina development in camera type eyeGO:00600411190.019
cellularizationGO:000734910.019
monovalent inorganic cation homeostasisGO:0055067330.019
positive regulation of protein complex assemblyGO:0031334450.019
regulation of neuron deathGO:19012141340.019
inorganic anion transmembrane transportGO:0098661290.019
cellular amine metabolic processGO:0044106440.018
cellular response to organic cyclic compoundGO:0071407870.018
positive regulation of ras gtpase activityGO:0032320650.018
regulation of clathrin mediated endocytosisGO:200036940.018
regulation of actin polymerization or depolymerizationGO:0008064450.018
regulation of cytokine productionGO:00018172660.018
anion transmembrane transportGO:0098656710.018
cardiac conductionGO:0061337170.018
response to nutrient levelsGO:00316671090.018
cell cell adhesionGO:0098609410.018
macromolecule methylationGO:00434141200.018
retina morphogenesis in camera type eyeGO:0060042450.017
metencephalon developmentGO:0022037890.017
protein localization to organelleGO:00333651850.017
mrna metabolic processGO:0016071840.017
chloride transmembrane transportGO:1902476240.017
positive regulation of dendrite developmentGO:1900006210.017
mitochondrion transport along microtubuleGO:004749730.017
actin polymerization or depolymerizationGO:0008154540.017
embryonic body morphogenesisGO:0010172100.017
regulation of g protein coupled receptor protein signaling pathwayGO:0008277370.017
axon guidanceGO:00074111410.017
establishment or maintenance of cell polarityGO:0007163860.017
response to osmotic stressGO:0006970210.017
membrane tubulationGO:009732040.017
amine metabolic processGO:0009308450.017
synaptic transmission glycinergicGO:006001220.017
regulation of actin cytoskeleton organizationGO:0032956840.017
cellular response to ammonium ionGO:007124220.017
regulation of long term neuronal synaptic plasticityGO:0048169190.016
regulation of synaptic growth at neuromuscular junctionGO:000858240.016
regulation of actin filament polymerizationGO:0030833380.016
positive regulation of transferase activityGO:00513471670.016
central nervous system myelinationGO:0022010120.016
receptor mediated endocytosisGO:0006898510.016
positive regulation of long term neuronal synaptic plasticityGO:004817030.016
organic hydroxy compound metabolic processGO:19016152030.016
sa node cell to atrial cardiac muscle cell signallingGO:008601840.016
sodium ion transmembrane transportGO:0035725490.016
cardiac muscle cell contractionGO:008600370.016
dna metabolic processGO:00062593030.016
membrane lipid biosynthetic processGO:0046467320.016
cellular component assembly involved in morphogenesisGO:00109271390.016
regulation of rho gtpase activityGO:0032319580.016
negative regulation of organelle organizationGO:0010639900.016
actin mediated cell contractionGO:0070252150.016
regulation of peptidase activityGO:0052547960.015
mitotic cell cycleGO:00002781950.015
mechanoreceptor differentiationGO:0042490670.015
digestive tract morphogenesisGO:00485461470.015
clathrin coat assemblyGO:004826820.015
negative regulation of phosphorus metabolic processGO:00105631840.015
regulation of transporter activityGO:0032409570.015
regulation of neuron apoptotic processGO:00435231220.015
behavioral defense responseGO:0002209280.015
positive regulation of secretion by cellGO:19035321140.015
divalent metal ion transportGO:00708381720.015
skeletal muscle organ developmentGO:00605381630.014
rna processingGO:00063961050.014
regulation of actin filament lengthGO:0030832450.014
regulation of homeostatic processGO:00328441820.014
reproductive behaviorGO:0019098320.014
ventricular cardiac muscle cell action potentialGO:008600540.014
detection of stimulusGO:0051606840.014
regulation of protein serine threonine kinase activityGO:00719001570.014
epidermis developmentGO:00085441870.014
actin cytoskeleton organizationGO:00300362200.014
hormone metabolic processGO:0042445860.014
positive regulation of cell migrationGO:00303351090.014
positive regulation of purine nucleotide metabolic processGO:19005441140.014
neuron projection guidanceGO:00974851410.014
homeostasis of number of cellsGO:00488722100.014
epithelial tube morphogenesisGO:00605623030.014
tissue homeostasisGO:00018941150.014
negative regulation of neuron deathGO:1901215980.014
single organismal cell cell adhesionGO:00163371310.014
regulation of heart rateGO:0002027360.014
regulation of inhibitory postsynaptic membrane potentialGO:0060080130.014
nucleoside monophosphate metabolic processGO:0009123850.014
synaptic vesicle membrane organizationGO:004849910.014
behavioral fear responseGO:0001662280.014
nuclear divisionGO:00002801580.014
metal ion homeostasisGO:00550651890.013
visual perceptionGO:0007601520.013
mesodermal cell migrationGO:000807840.013
methylationGO:00322591340.013
regulation of metal ion transportGO:00109591060.013
regulation of axon diameterGO:003113360.013
microtubule polymerization or depolymerizationGO:0031109260.013
neuron maturationGO:0042551290.013
positive regulation of map kinase activityGO:0043406840.013
neuronal action potential propagationGO:001922780.013
peptidyl amino acid modificationGO:00181933360.013
synaptic transmission gabaergicGO:0051932190.013
neuron apoptotic processGO:00514021420.013
transcription from rna polymerase iii promoterGO:000638330.013
excretionGO:0007588220.013
leukocyte differentiationGO:00025213420.013
wound healingGO:00420601570.013
regulation of cell adhesionGO:00301551540.013
posttranscriptional regulation of gene expressionGO:00106081550.013
regulation of cellular response to stressGO:00801351590.013
intracellular protein transportGO:00068862040.013
negative regulation of intracellular signal transductionGO:19025321670.013
microtubule nucleationGO:000702020.012
asymmetric stem cell divisionGO:009872230.012
positive regulation of secretionGO:00510471300.012
regulation of synaptic vesicle transportGO:1902803130.012
axon ensheathmentGO:0008366760.012
feeding behaviorGO:0007631620.012
positive regulation of neuron deathGO:1901216280.012
directional locomotionGO:003305830.012
multi organism behaviorGO:0051705620.012
response to light stimulusGO:00094161350.012
cell cell junction assemblyGO:0007043270.012
inner ear morphogenesisGO:00424721010.012
apoptotic signaling pathwayGO:00971903060.012
amino acid transportGO:0006865610.012
ceramide biosynthetic processGO:0046513200.012
regulation of astrocyte differentiationGO:0048710200.012
regulation of erk1 and erk2 cascadeGO:0070372710.012
renal system developmentGO:00720012250.012
developmental cell growthGO:0048588840.012
heart contractionGO:0060047930.012
regulation of protein bindingGO:0043393600.012
branched chain amino acid transportGO:001580320.012
pole plasm assemblyGO:000731520.012
protein targetingGO:00066051430.012
cell maturationGO:00484691270.012
cochlea developmentGO:0090102350.012
transmission of nerve impulseGO:0019226760.012
neuron projection regenerationGO:0031102140.012
regulation of cell migrationGO:00303342190.012
positive regulation of excitatory postsynaptic membrane potentialGO:2000463140.012
fear responseGO:0042596330.011
acrosome reactionGO:0007340190.011
digestive system developmentGO:00551232000.011
cellular response to dna damage stimulusGO:00069742070.011
embryonic organ morphogenesisGO:00485622760.011
macromolecule catabolic processGO:00090572810.011
morphogenesis of a polarized epitheliumGO:0001738370.011
positive regulation of protein serine threonine kinase activityGO:00719021060.011
reflexGO:0060004220.011
intrinsic apoptotic signaling pathwayGO:00971931320.011
multi organism reproductive behaviorGO:0044705290.011
organelle fissionGO:00482851700.011
oligodendrocyte differentiationGO:0048709530.011
positive regulation of apoptotic signaling pathwayGO:2001235950.011
male courtship behaviorGO:000804920.011
cellular response to histamineGO:007142010.011
establishment of protein localization to organelleGO:00725941180.011
photoreceptor cell differentiationGO:0046530520.011
sensory perception of painGO:0019233470.011
positive regulation of intracellular transportGO:0032388700.011
multicellular organismal homeostasisGO:00488711640.010
multi multicellular organism processGO:00447061090.010
cytokinetic processGO:003250620.010
oocyte axis specificationGO:000730920.010
chemotaxisGO:00069352470.010
memoryGO:0007613580.010
regulation of heart contractionGO:0008016770.010
digestive tract developmentGO:00485651900.010
mitotic cell cycle processGO:19030471590.010
negative regulation of protein metabolic processGO:00512482820.010
neuron projection extensionGO:1990138640.010
positive regulation of phagocytosis engulfmentGO:006010030.010
gastrulationGO:00073691160.010
positive regulation of protein transportGO:0051222930.010
ribonucleoprotein complex subunit organizationGO:0071826280.010
monocarboxylic acid transportGO:0015718440.010
peptidyl serine phosphorylationGO:0018105740.010
sodium ion exportGO:007143620.010
skeletal system developmentGO:00015013560.010

Pclo disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.088
disease of anatomical entityDOID:700.088
central nervous system diseaseDOID:33100.040
eye and adnexa diseaseDOID:149200.023
retinal degenerationDOID:846600.023
eye diseaseDOID:561400.023
retinal diseaseDOID:567900.023
sensory system diseaseDOID:005015500.023
brain diseaseDOID:93600.017
neuropathyDOID:87000.011
disease of mental healthDOID:15000.010