| regulation of mapk cascade | GO:0043408 | 248 | 0.995 | |
| platelet derived growth factor receptor signaling pathway | GO:0048008 | 32 | 0.993 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.992 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.986 | |
| fibroblast growth factor receptor signaling pathway | GO:0008543 | 46 | 0.951 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 1 | 0.947 | |
| response to oxidative stress | GO:0006979 | 123 | 0.947 | Rat |
| leukocyte differentiation | GO:0002521 | 342 | 0.944 | |
| positive regulation of kinase activity | GO:0033674 | 155 | 0.906 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.901 | |
| negative regulation of peptidyl tyrosine phosphorylation | GO:0050732 | 17 | 0.892 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 0 | 0.879 | |
| epidermal growth factor receptor signaling pathway | GO:0007173 | 28 | 0.873 | |
| cellular response to fibroblast growth factor stimulus | GO:0044344 | 47 | 0.850 | |
| rho protein signal transduction | GO:0007266 | 32 | 0.832 | |
| regulation of ras gtpase activity | GO:0032318 | 88 | 0.827 | |
| endocytosis | GO:0006897 | 168 | 0.824 | |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.819 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.816 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.798 | |
| myeloid leukocyte differentiation | GO:0002573 | 119 | 0.780 | |
| negative regulation of granulocyte differentiation | GO:0030853 | 3 | 0.780 | |
| regulation of mast cell activation | GO:0033003 | 21 | 0.770 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.769 | |
| regulation of b cell differentiation | GO:0045577 | 23 | 0.766 | |
| amine metabolic process | GO:0009308 | 45 | 0.759 | |
| regulation of rho gtpase activity | GO:0032319 | 58 | 0.758 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.757 | |
| negative regulation of receptor activity | GO:2000272 | 5 | 0.721 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.720 | |
| regulation of ras protein signal transduction | GO:0046578 | 114 | 0.717 | |
| regulation of map kinase activity | GO:0043405 | 120 | 0.714 | |
| positive regulation of intracellular transport | GO:0032388 | 70 | 0.701 | |
| alcohol catabolic process | GO:0046164 | 16 | 0.700 | |
| regulation of antigen receptor mediated signaling pathway | GO:0050854 | 29 | 0.692 | |
| positive regulation of rac gtpase activity | GO:0032855 | 14 | 0.683 | |
| negative regulation of cell activation | GO:0050866 | 111 | 0.681 | |
| osteoclast differentiation | GO:0030316 | 62 | 0.678 | |
| regulation of vesicle mediated transport | GO:0060627 | 139 | 0.674 | |
| positive regulation of rho gtpase activity | GO:0032321 | 41 | 0.670 | |
| regulation of lymphocyte differentiation | GO:0045619 | 107 | 0.666 | |
| lysosome localization | GO:0032418 | 20 | 0.652 | |
| developmental growth involved in morphogenesis | GO:0060560 | 138 | 0.646 | |
| phosphatidylinositol metabolic process | GO:0046488 | 45 | 0.643 | |
| response to fibroblast growth factor | GO:0071774 | 47 | 0.637 | |
| regulation of anatomical structure size | GO:0090066 | 178 | 0.631 | Rat |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.625 | |
| positive regulation of leukocyte mediated immunity | GO:0002705 | 70 | 0.623 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.617 | |
| mitochondrion distribution | GO:0048311 | 4 | 0.616 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.616 | Rat |
| negative regulation of protein tyrosine kinase activity | GO:0061099 | 3 | 0.614 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.604 | |
| lipid storage | GO:0019915 | 36 | 0.601 | |
| response to growth factor | GO:0070848 | 198 | 0.600 | |
| synaptic vesicle recycling | GO:0036465 | 19 | 0.589 | |
| erbb signaling pathway | GO:0038127 | 32 | 0.573 | |
| negative regulation of epidermal growth factor activated receptor activity | GO:0007175 | 3 | 0.556 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.554 | |
| guanosine containing compound metabolic process | GO:1901068 | 144 | 0.537 | |
| regulation of mast cell activation involved in immune response | GO:0033006 | 17 | 0.526 | |
| mapk cascade | GO:0000165 | 281 | 0.525 | |
| regulation of epidermal growth factor activated receptor activity | GO:0007176 | 7 | 0.523 | |
| gland development | GO:0048732 | 330 | 0.517 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.515 | |
| positive regulation of extrinsic apoptotic signaling pathway via death domain receptors | GO:1902043 | 13 | 0.504 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.500 | |
| regeneration | GO:0031099 | 38 | 0.499 | Rat |
| glycerophospholipid metabolic process | GO:0006650 | 71 | 0.496 | |
| labyrinthine layer development | GO:0060711 | 49 | 0.493 | |
| positive regulation of leukocyte differentiation | GO:1902107 | 86 | 0.484 | |
| peptidyl serine modification | GO:0018209 | 83 | 0.478 | |
| negative regulation of protein phosphorylation | GO:0001933 | 126 | 0.476 | |
| lens development in camera type eye | GO:0002088 | 62 | 0.476 | |
| urogenital system development | GO:0001655 | 261 | 0.470 | |
| cellular response to peptide | GO:1901653 | 92 | 0.467 | Rat |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.459 | |
| regulation of t cell activation | GO:0050863 | 170 | 0.451 | |
| response to peptide hormone | GO:0043434 | 127 | 0.444 | Rat |
| dephosphorylation | GO:0016311 | 129 | 0.438 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.433 | |
| organic hydroxy compound catabolic process | GO:1901616 | 25 | 0.412 | |
| regulation of cell activation | GO:0050865 | 289 | 0.406 | |
| leukocyte proliferation | GO:0070661 | 172 | 0.405 | |
| negative regulation of map kinase activity | GO:0043407 | 34 | 0.404 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.398 | |
| immune response activating cell surface receptor signaling pathway | GO:0002429 | 72 | 0.391 | |
| b cell differentiation | GO:0030183 | 78 | 0.389 | |
| phospholipid dephosphorylation | GO:0046839 | 6 | 0.387 | |
| cell cycle g1 s phase transition | GO:0044843 | 57 | 0.381 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.381 | |
| regulation of leukocyte mediated immunity | GO:0002703 | 104 | 0.378 | |
| peptidyl threonine phosphorylation | GO:0018107 | 31 | 0.373 | |
| intracellular distribution of mitochondria | GO:0048312 | 1 | 0.371 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.369 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.368 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.367 | |
| terminal button organization | GO:0072553 | 3 | 0.362 | |
| t cell receptor signaling pathway | GO:0050852 | 46 | 0.360 | |
| germ cell development | GO:0007281 | 185 | 0.357 | |
| organelle localization | GO:0051640 | 179 | 0.357 | |
| regulation of lymphocyte proliferation | GO:0050670 | 117 | 0.357 | |
| activation of rac gtpase activity | GO:0032863 | 2 | 0.350 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.349 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.349 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.347 | |
| t cell proliferation | GO:0042098 | 120 | 0.346 | |
| inositol phosphate catabolic process | GO:0071545 | 4 | 0.344 | |
| organ regeneration | GO:0031100 | 2 | 0.342 | Rat |
| synaptic transmission | GO:0007268 | 329 | 0.340 | Mouse |
| small molecule catabolic process | GO:0044282 | 71 | 0.336 | |
| positive regulation of map kinase activity | GO:0043406 | 84 | 0.327 | |
| axonogenesis | GO:0007409 | 274 | 0.326 | |
| olfactory learning | GO:0008355 | 2 | 0.326 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.321 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.321 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.320 | |
| protein localization to nucleus | GO:0034504 | 121 | 0.319 | |
| regulation of protein tyrosine kinase activity | GO:0061097 | 17 | 0.318 | |
| cytokine mediated signaling pathway | GO:0019221 | 115 | 0.315 | |
| cytokine production | GO:0001816 | 319 | 0.310 | |
| regionalization | GO:0003002 | 337 | 0.308 | |
| regulation of insulin receptor signaling pathway | GO:0046626 | 21 | 0.305 | |
| skeletal system morphogenesis | GO:0048705 | 203 | 0.305 | |
| t cell tolerance induction | GO:0002517 | 6 | 0.300 | |
| synaptic vesicle localization | GO:0097479 | 59 | 0.298 | |
| negative regulation of mapk cascade | GO:0043409 | 65 | 0.297 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.296 | |
| regulation of actin cytoskeleton organization | GO:0032956 | 84 | 0.295 | |
| rac protein signal transduction | GO:0016601 | 13 | 0.293 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.292 | Rat |
| humoral immune response | GO:0006959 | 57 | 0.291 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.291 | |
| positive regulation of protein catabolic process | GO:0045732 | 60 | 0.290 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.290 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.287 | |
| negative regulation of erbb signaling pathway | GO:1901185 | 7 | 0.286 | |
| positive regulation of myeloid leukocyte mediated immunity | GO:0002888 | 14 | 0.284 | |
| photoreceptor cell differentiation | GO:0046530 | 52 | 0.283 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.281 | |
| erk1 and erk2 cascade | GO:0070371 | 77 | 0.280 | |
| calcium ion transport into cytosol | GO:0060402 | 48 | 0.276 | |
| neural precursor cell proliferation | GO:0061351 | 121 | 0.276 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.275 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.275 | |
| blood vessel morphogenesis | GO:0048514 | 285 | 0.274 | |
| negative regulation of epidermal growth factor receptor signaling pathway | GO:0042059 | 6 | 0.271 | |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 77 | 0.271 | |
| protein catabolic process | GO:0030163 | 221 | 0.271 | |
| positive regulation of gtpase activity | GO:0043547 | 85 | 0.268 | |
| immune effector process | GO:0002252 | 321 | 0.265 | Fly |
| regulation of protein serine threonine kinase activity | GO:0071900 | 157 | 0.265 | |
| myotube differentiation | GO:0014902 | 105 | 0.264 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.254 | |
| response to peptide | GO:1901652 | 136 | 0.252 | Rat |
| glycerolipid biosynthetic process | GO:0045017 | 50 | 0.252 | |
| monocyte differentiation | GO:0030224 | 9 | 0.252 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.251 | |
| positive regulation of t cell tolerance induction | GO:0002666 | 6 | 0.251 | |
| synaptic vesicle transport | GO:0048489 | 57 | 0.248 | |
| fused antrum stage | GO:0048165 | 1 | 0.246 | |
| forebrain development | GO:0030900 | 302 | 0.244 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.240 | |
| protein kinase b signaling | GO:0043491 | 74 | 0.239 | |
| embryonic placenta development | GO:0001892 | 98 | 0.239 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.238 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 95 | 0.235 | |
| regulation of rho protein signal transduction | GO:0035023 | 71 | 0.234 | |
| neuron projection extension | GO:1990138 | 64 | 0.234 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.233 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.233 | |
| cell cell signaling involved in cell fate commitment | GO:0045168 | 35 | 0.231 | |
| intracellular protein transport | GO:0006886 | 204 | 0.231 | |
| myeloid leukocyte activation | GO:0002274 | 83 | 0.229 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.228 | |
| phosphorylated carbohydrate dephosphorylation | GO:0046838 | 4 | 0.228 | |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.228 | |
| positive regulation of cell migration | GO:0030335 | 109 | 0.224 | |
| release of sequestered calcium ion into cytosol | GO:0051209 | 42 | 0.222 | |
| positive regulation of protein kinase b signaling | GO:0051897 | 32 | 0.221 | |
| neutrophil differentiation | GO:0030223 | 3 | 0.220 | |
| guanosine containing compound catabolic process | GO:1901069 | 144 | 0.219 | |
| activation of mapk activity | GO:0000187 | 59 | 0.218 | |
| regulation of lung blood pressure | GO:0014916 | 2 | 0.218 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.215 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.215 | |
| regulation of receptor activity | GO:0010469 | 41 | 0.213 | |
| regulation of ion transport | GO:0043269 | 215 | 0.211 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.210 | |
| establishment of organelle localization | GO:0051656 | 122 | 0.210 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.209 | |
| actin filament organization | GO:0007015 | 113 | 0.209 | |
| regulation of leukocyte differentiation | GO:1902105 | 159 | 0.208 | |
| lymphocyte differentiation | GO:0030098 | 242 | 0.206 | |
| t cell activation | GO:0042110 | 289 | 0.204 | |
| t cell anergy | GO:0002870 | 4 | 0.203 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.202 | |
| positive regulation of cytoplasmic transport | GO:1903651 | 40 | 0.200 | |
| positive regulation of tolerance induction | GO:0002645 | 8 | 0.197 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.197 | |
| digestive system development | GO:0055123 | 200 | 0.197 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.196 | |
| insulin receptor signaling pathway | GO:0008286 | 49 | 0.191 | Rat |
| regulation of jun kinase activity | GO:0043506 | 40 | 0.190 | |
| positive regulation of jun kinase activity | GO:0043507 | 30 | 0.190 | |
| regulation of homeostatic process | GO:0032844 | 182 | 0.190 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.189 | |
| regulation of tolerance induction to self antigen | GO:0002649 | 1 | 0.188 | |
| negative regulation of immune system process | GO:0002683 | 209 | 0.187 | |
| regulation of cellular senescence | GO:2000772 | 6 | 0.186 | |
| skin development | GO:0043588 | 220 | 0.185 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.184 | |
| lateral inhibition | GO:0046331 | 1 | 0.184 | |
| protein targeting | GO:0006605 | 143 | 0.181 | |
| positive regulation of ras gtpase activity | GO:0032320 | 65 | 0.179 | |
| myeloid cell homeostasis | GO:0002262 | 114 | 0.178 | |
| vesicle localization | GO:0051648 | 86 | 0.178 | |
| regulation of actin filament based process | GO:0032970 | 99 | 0.173 | |
| negative regulation of bone remodeling | GO:0046851 | 6 | 0.172 | |
| regulation of cell migration | GO:0030334 | 219 | 0.168 | |
| cell activation involved in immune response | GO:0002263 | 126 | 0.167 | |
| regulation of autophagy | GO:0010506 | 30 | 0.166 | |
| establishment of vesicle localization | GO:0051650 | 81 | 0.165 | |
| stress activated protein kinase signaling cascade | GO:0031098 | 81 | 0.163 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.163 | |
| positive regulation of t cell differentiation | GO:0045582 | 52 | 0.163 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.159 | |
| skeletal system development | GO:0001501 | 356 | 0.159 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.158 | |
| regulation of jnk cascade | GO:0046328 | 62 | 0.158 | |
| regulation of t cell differentiation | GO:0045580 | 83 | 0.157 | |
| t cell differentiation | GO:0030217 | 174 | 0.157 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.155 | |
| positive regulation of extrinsic apoptotic signaling pathway | GO:2001238 | 34 | 0.155 | |
| transmembrane transport | GO:0055085 | 412 | 0.155 | |
| activation of jun kinase activity | GO:0007257 | 15 | 0.155 | |
| positive regulation of cell activation | GO:0050867 | 158 | 0.154 | |
| regulation of cytoskeleton organization | GO:0051493 | 122 | 0.153 | |
| gtp catabolic process | GO:0006184 | 143 | 0.153 | |
| immune response activating signal transduction | GO:0002757 | 116 | 0.153 | |
| endomembrane system organization | GO:0010256 | 147 | 0.153 | |
| regulation of cell motility | GO:2000145 | 236 | 0.152 | |
| regulation of epithelial cell proliferation | GO:0050678 | 141 | 0.152 | |
| male sex differentiation | GO:0046661 | 109 | 0.151 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.151 | |
| cellular component assembly involved in morphogenesis | GO:0010927 | 139 | 0.150 | |
| negative regulation of b cell receptor signaling pathway | GO:0050859 | 4 | 0.149 | |
| gtp metabolic process | GO:0046039 | 144 | 0.149 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.148 | |
| regulation of mast cell degranulation | GO:0043304 | 16 | 0.148 | |
| mast cell degranulation | GO:0043303 | 19 | 0.147 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.147 | |
| embryonic organ morphogenesis | GO:0048562 | 276 | 0.147 | |
| gastrulation | GO:0007369 | 116 | 0.146 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.146 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.145 | |
| negative regulation of osteoclast differentiation | GO:0045671 | 12 | 0.145 | |
| regulation of cell projection organization | GO:0031344 | 206 | 0.144 | |
| maintenance of location | GO:0051235 | 89 | 0.144 | |
| stress activated mapk cascade | GO:0051403 | 80 | 0.143 | |
| regulation of terminal button organization | GO:2000331 | 1 | 0.142 | |
| growth plate cartilage chondrocyte growth | GO:0003430 | 2 | 0.142 | |
| b cell proliferation | GO:0042100 | 53 | 0.138 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.138 | |
| negative regulation of leukocyte proliferation | GO:0070664 | 46 | 0.137 | |
| jnk cascade | GO:0007254 | 72 | 0.136 | |
| neuroblast proliferation | GO:0007405 | 49 | 0.136 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.136 | |
| autophagy | GO:0006914 | 45 | 0.133 | |
| regulation of nucleoside metabolic process | GO:0009118 | 130 | 0.133 | |
| tissue remodeling | GO:0048771 | 102 | 0.132 | |
| spermatid development | GO:0007286 | 108 | 0.132 | |
| axon extension involved in axon guidance | GO:0048846 | 14 | 0.132 | |
| lens fiber cell apoptotic process | GO:1990086 | 4 | 0.132 | |
| lipid localization | GO:0010876 | 126 | 0.131 | |
| response to uv | GO:0009411 | 44 | 0.131 | |
| gastrulation with mouth forming second | GO:0001702 | 29 | 0.130 | |
| negative regulation of kinase activity | GO:0033673 | 81 | 0.130 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.127 | |
| protein localization to organelle | GO:0033365 | 185 | 0.126 | |
| dendritic spine organization | GO:0097061 | 26 | 0.126 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.126 | |
| positive regulation of leukocyte degranulation | GO:0043302 | 10 | 0.125 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.124 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.123 | |
| single organismal cell cell adhesion | GO:0016337 | 131 | 0.122 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.120 | |
| positive regulation of mast cell degranulation | GO:0043306 | 10 | 0.119 | |
| placenta development | GO:0001890 | 140 | 0.119 | |
| positive regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032436 | 23 | 0.118 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.117 | |
| regulation of tolerance induction | GO:0002643 | 10 | 0.117 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.116 | |
| positive regulation of protein serine threonine kinase activity | GO:0071902 | 106 | 0.116 | |
| tissue regeneration | GO:0042246 | 22 | 0.115 | |
| positive regulation of stress activated mapk cascade | GO:0032874 | 48 | 0.114 | |
| regulation of erythrocyte differentiation | GO:0045646 | 23 | 0.114 | |
| regulation of myeloid leukocyte differentiation | GO:0002761 | 58 | 0.113 | |
| protein import into nucleus | GO:0006606 | 95 | 0.112 | |
| optic placode formation | GO:0001743 | 2 | 0.112 | |
| immune response regulating cell surface receptor signaling pathway | GO:0002768 | 80 | 0.112 | |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.111 | |
| spermatid differentiation | GO:0048515 | 115 | 0.110 | |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.110 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.110 | |
| ruffle organization | GO:0031529 | 16 | 0.108 | |
| canonical wnt signaling pathway | GO:0060070 | 130 | 0.108 | |
| positive regulation of b cell differentiation | GO:0045579 | 13 | 0.108 | |
| regulation of t cell proliferation | GO:0042129 | 92 | 0.107 | |
| response to endoplasmic reticulum stress | GO:0034976 | 53 | 0.107 | Worm |
| response to sterol | GO:0036314 | 4 | 0.106 | |
| regulation of nucleotide catabolic process | GO:0030811 | 122 | 0.106 | |
| compound eye development | GO:0048749 | 1 | 0.105 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.105 | |
| angiogenesis | GO:0001525 | 201 | 0.105 | |
| stem cell development | GO:0048864 | 219 | 0.101 | |
| lateral mesoderm morphogenesis | GO:0048369 | 3 | 0.101 | |
| epidermis development | GO:0008544 | 187 | 0.101 | |
| regulation of dendritic spine morphogenesis | GO:0061001 | 17 | 0.100 | |
| female sex differentiation | GO:0046660 | 84 | 0.099 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.098 | |
| regulation of lymphocyte anergy | GO:0002911 | 4 | 0.098 | |
| cell chemotaxis | GO:0060326 | 81 | 0.097 | |
| regulation of leukocyte proliferation | GO:0070663 | 121 | 0.097 | |
| protein ubiquitination | GO:0016567 | 171 | 0.097 | |
| positive regulation of lymphocyte anergy | GO:0002913 | 4 | 0.097 | |
| neuron projection extension involved in neuron projection guidance | GO:1902284 | 14 | 0.096 | |
| positive regulation of myeloid cell differentiation | GO:0045639 | 43 | 0.096 | |
| gonad development | GO:0008406 | 141 | 0.095 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.095 | |
| photoreceptor cell development | GO:0042461 | 40 | 0.094 | |
| positive regulation of gtp catabolic process | GO:0033126 | 85 | 0.094 | |
| locomotory behavior | GO:0007626 | 195 | 0.094 | |
| regulation of osteoclast differentiation | GO:0045670 | 36 | 0.094 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.094 | |
| cell aging | GO:0007569 | 35 | 0.094 | |
| synaptic vesicle endocytosis | GO:0048488 | 19 | 0.093 | |
| cellular response to epidermal growth factor stimulus | GO:0071364 | 4 | 0.093 | |
| actin filament polymerization | GO:0030041 | 44 | 0.093 | |
| positive regulation of immune effector process | GO:0002699 | 107 | 0.092 | |
| regulation of smad protein import into nucleus | GO:0060390 | 3 | 0.092 | |
| determination of adult lifespan | GO:0008340 | 11 | 0.092 | |
| axon guidance | GO:0007411 | 141 | 0.091 | |
| inositol lipid mediated signaling | GO:0048017 | 41 | 0.091 | |
| digestive tract morphogenesis | GO:0048546 | 147 | 0.090 | |
| single organism cell adhesion | GO:0098602 | 156 | 0.089 | |
| bone resorption | GO:0045453 | 38 | 0.089 | |
| neural plate mediolateral regionalization | GO:0021998 | 1 | 0.088 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.088 | |
| regulation of endocytosis | GO:0030100 | 69 | 0.087 | |
| myeloid cell activation involved in immune response | GO:0002275 | 34 | 0.087 | |
| single organism nuclear import | GO:1902593 | 95 | 0.086 | |
| bronchus morphogenesis | GO:0060434 | 2 | 0.086 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.085 | |
| regulation of t cell tolerance induction | GO:0002664 | 6 | 0.084 | |
| protein import | GO:0017038 | 101 | 0.084 | |
| response to epidermal growth factor | GO:0070849 | 4 | 0.082 | |
| multicellular organismal aging | GO:0010259 | 24 | 0.082 | |
| regulation of secretion by cell | GO:1903530 | 249 | 0.082 | |
| positive regulation of reactive oxygen species metabolic process | GO:2000379 | 11 | 0.081 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.081 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.081 | |
| tor signaling | GO:0031929 | 21 | 0.081 | Fly |
| cellular response to amino acid stimulus | GO:0071230 | 29 | 0.081 | |
| negative regulation of bone resorption | GO:0045779 | 6 | 0.081 | |
| negative regulation of homeostatic process | GO:0032845 | 71 | 0.080 | |
| positive regulation of b cell tolerance induction | GO:0002663 | 2 | 0.080 | |
| hexose metabolic process | GO:0019318 | 98 | 0.080 | |
| activation of immune response | GO:0002253 | 138 | 0.079 | |
| regulation of cell projection assembly | GO:0060491 | 38 | 0.078 | |
| regulation of t cell anergy | GO:0002667 | 4 | 0.078 | |
| response to radiation | GO:0009314 | 165 | 0.078 | |
| positive regulation of smad protein import into nucleus | GO:0060391 | 2 | 0.078 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.077 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.077 | |
| cellular response to insulin stimulus | GO:0032869 | 78 | 0.077 | Rat |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.077 | |
| response to cholesterol | GO:0070723 | 4 | 0.076 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.076 | |
| camera type eye development | GO:0043010 | 266 | 0.076 | |
| mast cell activation involved in immune response | GO:0002279 | 20 | 0.076 | |
| positive regulation of erythrocyte differentiation | GO:0045648 | 11 | 0.076 | |
| molting cycle | GO:0042303 | 90 | 0.076 | |
| positive regulation of lymphocyte differentiation | GO:0045621 | 61 | 0.075 | |
| phosphatidylinositol biosynthetic process | GO:0006661 | 15 | 0.075 | |
| bone morphogenesis | GO:0060349 | 78 | 0.075 | |
| positive regulation of protein import into nucleus | GO:0042307 | 26 | 0.075 | |
| negative regulation of cell development | GO:0010721 | 169 | 0.075 | |
| activation of mapkk activity | GO:0000186 | 15 | 0.075 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.075 | |
| negative regulation of antigen receptor mediated signaling pathway | GO:0050858 | 16 | 0.075 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.074 | |
| cell recognition | GO:0008037 | 83 | 0.073 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 122 | 0.073 | |
| mammary gland morphogenesis | GO:0060443 | 54 | 0.073 | |
| response to calcium ion | GO:0051592 | 20 | 0.073 | |
| negative regulation of transferase activity | GO:0051348 | 85 | 0.072 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.072 | |
| regulation of neuronal synaptic plasticity | GO:0048168 | 30 | 0.071 | |
| regulation of anti mullerian hormone signaling pathway | GO:1902612 | 1 | 0.071 | |
| regulation of stress activated mapk cascade | GO:0032872 | 69 | 0.071 | |
| actin cytoskeleton reorganization | GO:0031532 | 21 | 0.070 | |
| activation of ras gtpase activity | GO:0032856 | 11 | 0.069 | |
| regulation of cell adhesion | GO:0030155 | 154 | 0.069 | |
| macrophage differentiation | GO:0030225 | 20 | 0.069 | |
| morphogenesis of a branching structure | GO:0001763 | 203 | 0.069 | |
| stem cell maintenance | GO:0019827 | 130 | 0.069 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.069 | |
| regulated secretory pathway | GO:0045055 | 32 | 0.067 | |
| organophosphate biosynthetic process | GO:0090407 | 122 | 0.067 | |
| leukocyte mediated immunity | GO:0002443 | 174 | 0.067 | |
| bone remodeling | GO:0046849 | 53 | 0.067 | |
| regulation of muscle tissue development | GO:1901861 | 97 | 0.067 | |
| inorganic ion transmembrane transport | GO:0098660 | 234 | 0.066 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.066 | |
| epithelial tube morphogenesis | GO:0060562 | 303 | 0.066 | |
| cellular senescence | GO:0090398 | 11 | 0.066 | |
| mitochondrion organization | GO:0007005 | 134 | 0.065 | |
| regulation of epidermal growth factor receptor signaling pathway | GO:0042058 | 13 | 0.065 | |
| positive regulation of t cell mediated cytotoxicity | GO:0001916 | 15 | 0.065 | |
| regulation of synaptic vesicle recycling | GO:1903421 | 2 | 0.065 | |
| dendritic spine development | GO:0060996 | 30 | 0.064 | |
| innate immune response | GO:0045087 | 157 | 0.064 | Fly |
| immunoglobulin mediated immune response | GO:0016064 | 69 | 0.064 | |
| optic placode formation involved in camera type eye formation | GO:0046619 | 2 | 0.064 | |
| positive regulation of cellular protein catabolic process | GO:1903364 | 34 | 0.064 | |
| mullerian duct regression | GO:0001880 | 1 | 0.064 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.063 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.062 | |
| membrane organization | GO:0061024 | 245 | 0.062 | |
| circulatory system process | GO:0003013 | 197 | 0.062 | Rat |
| insulin secretion | GO:0030073 | 89 | 0.062 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.062 | |
| response to monosaccharide | GO:0034284 | 67 | 0.062 | |
| sequestering of metal ion | GO:0051238 | 19 | 0.062 | |
| glycerolipid metabolic process | GO:0046486 | 122 | 0.062 | |
| regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032434 | 40 | 0.061 | |
| positive regulation of mitotic cell cycle | GO:0045931 | 41 | 0.061 | |
| lateral mesodermal cell differentiation | GO:0048371 | 3 | 0.061 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 40 | 0.060 | |
| positive regulation of proteolysis | GO:0045862 | 85 | 0.060 | |
| lymphocyte anergy | GO:0002249 | 4 | 0.060 | |
| ruffle assembly | GO:0097178 | 13 | 0.060 | |
| regulation of exocytosis | GO:0017157 | 61 | 0.060 | |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.060 | |
| tolerance induction to self antigen | GO:0002513 | 4 | 0.060 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.060 | |
| anti mullerian hormone signaling pathway | GO:1990262 | 1 | 0.059 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 91 | 0.059 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.059 | |
| regulation of rac protein signal transduction | GO:0035020 | 19 | 0.059 | |
| cellular homeostasis | GO:0019725 | 240 | 0.058 | |
| maintenance of protein location in nucleus | GO:0051457 | 2 | 0.058 | |
| actin polymerization or depolymerization | GO:0008154 | 54 | 0.058 | |
| organelle assembly | GO:0070925 | 177 | 0.058 | |
| endochondral bone morphogenesis | GO:0060350 | 50 | 0.058 | |
| positive regulation of proteolysis involved in cellular protein catabolic process | GO:1903052 | 31 | 0.058 | |
| regulation of cell size | GO:0008361 | 72 | 0.058 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.057 | |
| peptidyl threonine modification | GO:0018210 | 31 | 0.057 | |
| trivalent inorganic cation transport | GO:0072512 | 5 | 0.057 | |
| positive regulation of skeletal muscle tissue regeneration | GO:0043415 | 4 | 0.057 | |
| positive regulation of exocytosis | GO:0045921 | 20 | 0.057 | |
| negative regulation of ras protein signal transduction | GO:0046580 | 18 | 0.056 | |
| b cell tolerance induction | GO:0002514 | 2 | 0.056 | |
| fatty acid metabolic process | GO:0006631 | 121 | 0.056 | |
| negative regulation of lymphocyte activation | GO:0051250 | 91 | 0.055 | |
| regulation of neutrophil differentiation | GO:0045658 | 2 | 0.055 | |
| regulation of excitatory postsynaptic membrane potential | GO:0060079 | 41 | 0.055 | |
| spermatogenesis | GO:0007283 | 284 | 0.055 | |
| regulation of protein localization | GO:0032880 | 231 | 0.055 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 243 | 0.055 | |
| branching morphogenesis of an epithelial tube | GO:0048754 | 159 | 0.055 | |
| male gamete generation | GO:0048232 | 285 | 0.054 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.054 | |
| blastocyst development | GO:0001824 | 80 | 0.054 | |
| positive regulation of protein localization to nucleus | GO:1900182 | 30 | 0.054 | |
| positive regulation of cell cycle | GO:0045787 | 92 | 0.054 | |
| mitochondrion localization | GO:0051646 | 9 | 0.054 | |
| regulation of b cell tolerance induction | GO:0002661 | 2 | 0.053 | |
| engulfment of apoptotic cell | GO:0043652 | 3 | 0.053 | |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.053 | |
| regulation of erk1 and erk2 cascade | GO:0070372 | 71 | 0.052 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.052 | |
| regulation of embryonic development | GO:0045995 | 71 | 0.052 | |
| myosin filament assembly | GO:0031034 | 2 | 0.052 | |
| sulfur compound metabolic process | GO:0006790 | 100 | 0.052 | |
| renal system development | GO:0072001 | 225 | 0.052 | |
| exocytosis | GO:0006887 | 121 | 0.052 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.051 | |