Mus musculus

5 known processes

Dio1

deiodinase, iodothyronine, type I

(Aliases: TXDI1,ITDI1,5DI,MGC107659,D1)

Dio1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
hormone metabolic processGO:0042445860.458
Mouse
lipid biosynthetic processGO:00086101790.381
organic hydroxy compound metabolic processGO:19016152030.367
Mouse
monocarboxylic acid metabolic processGO:00327871910.347
steroid metabolic processGO:00082021190.289
monosaccharide metabolic processGO:00059961060.284
cellular lipid metabolic processGO:00442553230.259
cellular ketone metabolic processGO:0042180840.231
carbohydrate metabolic processGO:00059752300.208
organic acid biosynthetic processGO:0016053860.185
glycerolipid metabolic processGO:00464861220.174
fatty acid metabolic processGO:00066311210.168
regulation of hormone levelsGO:00108172110.162
Mouse
small molecule biosynthetic processGO:00442831320.160
response to inorganic substanceGO:0010035960.158
carboxylic acid biosynthetic processGO:0046394860.148
naphthalene metabolic processGO:001893110.142
response to organic cyclic compoundGO:00140701980.136
cholesterol homeostasisGO:0042632440.123
oxidation reduction processGO:00551143420.113
ion transmembrane transportGO:00342203610.113
monocarboxylic acid biosynthetic processGO:0072330610.112
cellular response to hormone stimulusGO:00328701500.108
cellular amino acid metabolic processGO:00065201030.103
Mouse
cellular lipid catabolic processGO:0044242520.103
hexose metabolic processGO:0019318980.102
neutral lipid metabolic processGO:0006638570.087
lipid homeostasisGO:0055088630.087
protein processingGO:00164851630.086
regulation of phospholipase c activityGO:190027430.085
response to phenylpropanoidGO:0080184220.082
cellular modified amino acid metabolic processGO:0006575630.082
Mouse
cellular carbohydrate metabolic processGO:00442621190.081
protein maturationGO:00516041760.076
generation of precursor metabolites and energyGO:00060911030.075
vitamin d3 metabolic processGO:007064030.074
cation transportGO:00068123990.072
sterol homeostasisGO:0055092450.072
lipid transportGO:0006869980.072
response to organonitrogen compoundGO:00102432460.071
cellular amine metabolic processGO:0044106440.071
alcohol metabolic processGO:00060661160.070
regulation of cellular ketone metabolic processGO:0010565660.070
organic anion transportGO:00157111370.070
anion transportGO:00068201770.068
sensory perceptionGO:00076002450.067
hormone secretionGO:00468791280.067
amine metabolic processGO:0009308450.066
organic acid transportGO:00158491010.066
regulation of glucose metabolic processGO:0010906600.063
phospholipid metabolic processGO:0006644870.062
lipid localizationGO:00108761260.062
inorganic ion transmembrane transportGO:00986602340.062
small molecule catabolic processGO:0044282710.059
Mouse
isoprenoid metabolic processGO:0006720290.058
regulation of plasminogen activationGO:001075540.057
cellular response to cadmium ionGO:007127630.056
positive regulation of cellular amine metabolic processGO:003324050.056
cation transmembrane transportGO:00986552660.055
vitamin d biosynthetic processGO:004236830.055
regulation of lipid metabolic processGO:00192161180.055
response to metal ionGO:0010038470.053
positive regulation of cellular amino acid metabolic processGO:004576430.051
sensory perception of mechanical stimulusGO:00509541070.049
response to acid chemicalGO:00011011110.049
maintenance of locationGO:0051235890.048
response to peptideGO:19016521360.046
regulation of cellular carbohydrate metabolic processGO:0010675750.046
oxidative demethylationGO:007098910.046
response to nutrient levelsGO:00316671090.046
carboxylic acid transportGO:00469421000.044
rhythmic processGO:00485111740.044
muscle system processGO:00030121410.043
carboxylic acid catabolic processGO:0046395510.043
Mouse
carbohydrate derivative biosynthetic processGO:19011371830.043
peptide secretionGO:00027901140.043
transmembrane transportGO:00550854120.042
nitrogen compound transportGO:00717052710.042
placenta developmentGO:00018901400.042
cellular response to lipidGO:00713961450.041
glucose metabolic processGO:0006006920.040
transmission of nerve impulseGO:0019226760.040
epithelial cell developmentGO:00020641590.039
monocarboxylic acid catabolic processGO:0072329270.039
icosanoid metabolic processGO:0006690330.038
bile acid metabolic processGO:0008206170.038
acylglycerol metabolic processGO:0006639550.037
regulation of secretionGO:00510462740.037
cellular amide metabolic processGO:0043603580.036
naphthalene containing compound metabolic processGO:009042010.036
triglyceride metabolic processGO:0006641510.036
organic hydroxy compound biosynthetic processGO:1901617770.035
positive regulation of programmed cell deathGO:00430682180.035
muscle contractionGO:00069361010.035
sensory perception of soundGO:0007605970.034
establishment of blood nerve barrierGO:000806530.033
secondary alcohol metabolic processGO:190265230.033
energy derivation by oxidation of organic compoundsGO:0015980770.033
amide transportGO:00428861380.033
long chain fatty acid metabolic processGO:0001676260.033
wound healingGO:00420601570.033
positive regulation of lipid metabolic processGO:0045834400.033
renal system developmentGO:00720012250.032
multicellular organismal signalingGO:0035637910.032
response to lipopolysaccharideGO:00324961280.032
lipid catabolic processGO:0016042690.032
glucuronate metabolic processGO:001958520.032
response to temperature stimulusGO:0009266550.032
regulation of carbohydrate metabolic processGO:0006109750.031
carbon catabolite regulation of transcription from rna polymerase ii promoterGO:000042940.031
carbohydrate biosynthetic processGO:0016051740.031
regulation of body fluid levelsGO:00508781620.031
peptide metabolic processGO:0006518460.030
positive regulation of cell deathGO:00109422240.030
response to extracellular stimulusGO:00099911270.030
synaptic transmissionGO:00072683290.029
fatty acid oxidationGO:0019395280.029
cellular response to inorganic substanceGO:0071241370.029
urogenital system developmentGO:00016552610.029
response to starvationGO:0042594650.029
monosaccharide biosynthetic processGO:0046364440.029
regulation of cellular amine metabolic processGO:0033238200.029
peptide transportGO:00158331330.028
organic acid catabolic processGO:0016054510.028
Mouse
inflammatory responseGO:00069542440.028
gluconeogenesisGO:0006094390.028
response to steroid hormoneGO:0048545560.028
cell adhesionGO:00071553290.028
peptidyl amino acid modificationGO:00181933360.028
regulation of steroid biosynthetic processGO:0050810260.028
cellular homeostasisGO:00197252400.028
extracellular matrix organizationGO:00301981470.027
terpenoid metabolic processGO:0006721250.027
regulation of hormone secretionGO:0046883880.027
renal tubular secretionGO:009725420.027
metal ion homeostasisGO:00550651890.027
negative regulation of molecular functionGO:00440922580.027
blood circulationGO:00080151950.027
response to oxidative stressGO:00069791230.027
lipid modificationGO:0030258650.027
monocarboxylic acid transportGO:0015718440.026
negative regulation of protein metabolic processGO:00512482820.026
cellular response to steroid hormone stimulusGO:0071383330.026
fatty acid derivative metabolic processGO:1901568330.026
neuronal action potentialGO:0019228540.026
regulation of fatty acid metabolic processGO:0019217280.026
action potentialGO:0001508780.026
telencephalon developmentGO:00215371860.026
heme metabolic processGO:0042168160.026
carbohydrate homeostasisGO:00335001280.026
glycerophospholipid metabolic processGO:0006650710.026
morphogenesis of a branching epitheliumGO:00611381930.025
cell substrate adhesionGO:00315891300.025
response to stilbenoidGO:0035634220.025
inorganic cation transmembrane transportGO:00986622070.025
development of primary female sexual characteristicsGO:0046545730.024
regulation of kinase activityGO:00435492490.024
skeletal system developmentGO:00015013560.024
cellular response to organonitrogen compoundGO:00714171450.024
androgen biosynthetic processGO:000670240.024
circulatory system processGO:00030131970.024
pigment metabolic processGO:0042440320.024
hexose biosynthetic processGO:0019319390.024
detection of stimulusGO:0051606840.024
short chain fatty acid catabolic processGO:001962620.023
cell maturationGO:00484691270.023
organonitrogen compound biosynthetic processGO:19015661920.023
regulation of steroid metabolic processGO:0019218390.023
gland developmentGO:00487323300.023
lipid oxidationGO:0034440290.023
response to molecule of bacterial originGO:00022371430.023
purine containing compound metabolic processGO:00725213110.023
response to drugGO:0042493750.022
ensheathment of neuronsGO:0007272760.022
positive regulation of plasminogen activationGO:001075620.022
glycoprotein metabolic processGO:00091001160.022
fat soluble vitamin biosynthetic processGO:004236240.022
regulation of protein processingGO:0070613960.022
regulation of blood vessel sizeGO:0050880560.022
carbohydrate transportGO:0008643620.022
regulation of lipid biosynthetic processGO:0046890540.022
regulation of system processGO:00440572000.022
cellular response to insulin stimulusGO:0032869780.022
positive regulation of insulin receptor signaling pathwayGO:004662840.021
regulation of cholesterol metabolic processGO:0090181140.021
developmental maturationGO:00217001930.021
glucose transportGO:0015758560.021
regulation of transferase activityGO:00513382630.021
sulfur compound metabolic processGO:00067901000.020
sodium ion transmembrane transportGO:0035725490.020
extracellular structure organizationGO:00430621480.020
g protein coupled receptor signaling pathwayGO:00071862430.020
regulation of reactive oxygen species metabolic processGO:2000377400.020
engulfment of apoptotic cellGO:004365230.020
uronic acid metabolic processGO:000606320.020
diterpenoid metabolic processGO:0016101240.020
zymogen activationGO:0031638410.020
organic cyclic compound catabolic processGO:19013612950.020
Mouse
regulation of membrane potentialGO:00423911920.019
porphyrin containing compound metabolic processGO:0006778220.019
regulation of translationGO:0006417710.019
cellular response to testosterone stimulusGO:007139410.019
protein activation cascadeGO:0072376190.019
camera type eye developmentGO:00430102660.019
regulation of cell cycleGO:00517262810.019
response to estrogenGO:0043627240.019
arachidonic acid metabolic processGO:0019369140.019
regulation of blood pressureGO:0008217930.019
steroid biosynthetic processGO:0006694470.019
cellular alcohol biosynthetic processGO:004410830.019
ear developmentGO:00435832000.019
glycoprotein biosynthetic processGO:0009101890.018
endocrine system developmentGO:0035270980.018
sulfate assimilationGO:000010330.018
regulation of anatomical structure sizeGO:00900661780.018
fatty acid catabolic processGO:0009062250.018
cellular alcohol metabolic processGO:004410730.018
fatty acid biosynthetic processGO:0006633410.018
protein glycosylationGO:0006486550.018
response to xenobiotic stimulusGO:0009410130.018
regulation of protein maturationGO:1903317960.018
cellular response to extracellular stimulusGO:0031668810.018
regulation of peptide secretionGO:0002791770.018
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressureGO:000199830.017
nucleoside phosphate biosynthetic processGO:1901293790.017
cellular response to peptide hormone stimulusGO:0071375920.017
cellular response to organic cyclic compoundGO:0071407870.017
respiratory tube developmentGO:00303231670.017
phenol containing compound metabolic processGO:0018958600.017
Mouse
reactive oxygen species metabolic processGO:0072593840.017
establishment of protein localization to organelleGO:00725941180.017
negative regulation of cell proliferationGO:00082852960.017
regulation of hydrolase activityGO:00513362460.017
positive regulation of phospholipase activityGO:001051830.017
positive regulation of fatty acid oxidationGO:004632140.017
negative regulation of protein maturationGO:1903318790.017
positive regulation of apoptotic processGO:00430652170.017
amino acid transmembrane transportGO:0003333370.016
regulation of carbohydrate biosynthetic processGO:0043255400.016
cofactor metabolic processGO:0051186800.016
ribonucleoside triphosphate metabolic processGO:00091992200.016
hormone mediated signaling pathwayGO:0009755230.016
cholesterol metabolic processGO:0008203560.016
response to peptide hormoneGO:00434341270.016
aromatic compound catabolic processGO:00194392860.016
Mouse
progesterone metabolic processGO:004244840.016
calcitriol biosynthetic process from calciolGO:003637830.016
inter male aggressive behaviorGO:000212130.016
mesonephric epithelium developmentGO:0072163940.016
development of primary sexual characteristicsGO:00451371430.016
retinoid metabolic processGO:0001523240.016
purine nucleotide metabolic processGO:00061633020.015
regulation of neuron differentiationGO:00456642810.015
sensory organ morphogenesisGO:00905962420.015
posttranscriptional regulation of gene expressionGO:00106081550.015
intracellular receptor signaling pathwayGO:0030522740.015
proteoglycan biosynthetic processGO:0030166200.015
nucleobase containing small molecule metabolic processGO:00550863520.015
cell growthGO:00160491300.015
kidney developmentGO:00018222130.015
multicellular organism growthGO:00352641610.015
Mouse
cellular response to molecule of bacterial originGO:0071219830.015
negative regulation of growthGO:0045926990.015
nucleoside phosphate metabolic processGO:00067533380.015
cellular response to starvationGO:0009267570.015
protein oligomerizationGO:0051259670.015
regulation of response to woundingGO:19030341890.015
negative regulation of protein processingGO:0010955790.015
morphogenesis of a branching structureGO:00017632030.015
negative regulation of lipid metabolic processGO:0045833300.015
neurohypophysis developmentGO:002198520.015
single organism cell adhesionGO:00986021560.014
endocrine processGO:0050886390.014
regulation of tube sizeGO:0035150570.014
glycogen metabolic processGO:0005977320.014
mechanoreceptor differentiationGO:0042490670.014
vasoconstrictionGO:0042310270.014
negative regulation of gluconeogenesisGO:004572190.014
negative regulation of proteolysisGO:0045861740.014
regulation of erk1 and erk2 cascadeGO:0070372710.014
female sex differentiationGO:0046660840.014
cellular response to peptideGO:1901653920.014
immune effector processGO:00022523210.014
reactive nitrogen species metabolic processGO:200105700.014
myeloid leukocyte differentiationGO:00025731190.014
unsaturated fatty acid metabolic processGO:0033559310.014
male sex differentiationGO:00466611090.014
mapk cascadeGO:00001652810.014
regulation of cellular amino acid metabolic processGO:000652150.014
endocytosisGO:00068971680.014
protein autophosphorylationGO:0046777610.014
forebrain developmentGO:00309003020.014
prostate gland stromal morphogenesisGO:006074120.014
purine ribonucleoside metabolic processGO:00461282410.014
cellular chemical homeostasisGO:00550822150.014
organic hydroxy compound transportGO:0015850930.014
purine ribonucleotide metabolic processGO:00091502900.014
response to testosteroneGO:003357430.014
nephron developmentGO:00720061090.014
regulation of vesicle mediated transportGO:00606271390.013
female gonad developmentGO:0008585710.013
regulation of vitamin metabolic processGO:003065630.013
fertilizationGO:00095661270.013
fatty acid transportGO:0015908280.013
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.013
positive regulation of protein kinase activityGO:00458601440.013
appendage developmentGO:00487361660.013
very long chain fatty acid metabolic processGO:000003880.013
ectodermal cell differentiationGO:001066830.013
response to oxygen levelsGO:0070482620.013
carnitine transportGO:001587930.013
translationGO:0006412930.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.013
regulation of systemic arterial blood pressure by hormoneGO:0001990250.013
response to monosaccharideGO:0034284670.013
cellular response to nutrient levelsGO:0031669640.013
cation homeostasisGO:00550802120.013
purine containing compound biosynthetic processGO:0072522700.013
macromolecule glycosylationGO:0043413550.013
regulation of antimicrobial humoral responseGO:000275930.013
regulation of fatty acid oxidationGO:0046320100.013
negative regulation of immune system processGO:00026832090.012
organonitrogen compound catabolic processGO:19015652640.012
Mouse
regulation of secretion by cellGO:19035302490.012
single organismal cell cell adhesionGO:00163371310.012
regulation of apoptotic signaling pathwayGO:20012331970.012
carbon catabolite activation of transcriptionGO:004599140.012
positive regulation of transferase activityGO:00513471670.012
response to corticosteroneGO:005141210.012
regulation of triglyceride metabolic processGO:0090207170.012
regulation of homeostatic processGO:00328441820.012
male gamete generationGO:00482322850.012
glycosylationGO:0070085620.012
nucleoside monophosphate metabolic processGO:0009123850.012
benzene containing compound metabolic processGO:004253750.012
positive regulation of fatty acid biosynthetic processGO:004572330.012
regulation of peptide hormone secretionGO:0090276750.012
cellular nitrogen compound catabolic processGO:00442702800.012
sterol metabolic processGO:0016125580.012
fat cell differentiationGO:00454441600.012
limb developmentGO:00601731660.012
cell fate commitmentGO:00451652100.012
regulation of protein transportGO:00512231630.012
negative regulation of cellular carbohydrate metabolic processGO:0010677190.012
organophosphate catabolic processGO:00464342320.012
positive regulation of hydrolase activityGO:00513451480.012
ribose phosphate metabolic processGO:00196932910.012
monosaccharide transportGO:0015749580.012
regulation of intracellular transportGO:00323861590.011
testosterone biosynthetic processGO:006137020.011
peptide hormone secretionGO:00300721090.011
regulation of mapk cascadeGO:00434082480.011
purine ribonucleoside catabolic processGO:00461302050.011
ectodermal cell fate commitmentGO:000171210.011
cellular response to gonadotropin stimulusGO:007137140.011
mesonephros developmentGO:0001823970.011
cellular response to lipopolysaccharideGO:0071222770.011
gonad developmentGO:00084061410.011
membrane organizationGO:00610242450.011
regulation of defense responseGO:00313472330.011
organ growthGO:00352651170.011
sensory system developmentGO:004888030.011
kidney epithelium developmentGO:00720731210.011
regulation of systemic arterial blood pressure mediated by a chemical signalGO:0003044330.011
epithelial cell proliferationGO:00506731740.011
regulation of protein kinase activityGO:00458592320.011
female gamete generationGO:0007292740.011
response to insulinGO:00328681000.011
leukocyte differentiationGO:00025213420.011
vesicle organizationGO:0016050600.011
sulfur compound biosynthetic processGO:0044272370.011
axonogenesisGO:00074092740.011
cellular response to oxidative stressGO:0034599760.011
nuclear divisionGO:00002801580.011
negative regulation of cellular component organizationGO:00511291940.011
reactive oxygen species biosynthetic processGO:190340980.011
organelle fissionGO:00482851700.011
anion transmembrane transportGO:0098656710.011
macromolecule catabolic processGO:00090572810.011
secondary metabolic processGO:0019748180.011
polyol metabolic processGO:0019751260.011
purine nucleoside monophosphate metabolic processGO:0009126810.011
sensory perception of smellGO:0007608260.011
regulation of peptide transportGO:0090087910.011
axon ensheathmentGO:0008366760.011
response to osmotic stressGO:0006970210.011
amino acid betaine transportGO:001583830.011
nucleoside phosphate catabolic processGO:19012922220.011
chemotaxisGO:00069352470.011
purine ribonucleoside monophosphate metabolic processGO:0009167800.011
purine nucleoside triphosphate catabolic processGO:00091462030.011
molting cycleGO:0042303900.011
positive regulation of phospholipase c activityGO:001086320.011
regulation of cellular response to stressGO:00801351590.011
regulation of gluconeogenesisGO:0006111300.011
regulation of cell morphogenesis involved in differentiationGO:00107691510.011
myeloid cell differentiationGO:00300992330.010
cellular response to biotic stimulusGO:0071216920.010
regulation of transcription from rna polymerase iii promoterGO:000635920.010
mrna metabolic processGO:0016071840.010
nucleotide metabolic processGO:00091173320.010
cell recognitionGO:0008037830.010
purine nucleoside metabolic processGO:00422782410.010
muscle cell differentiationGO:00426922610.010
lateral line system developmentGO:004892510.010
lymphocyte mediated immunityGO:00024491390.010
cytoplasmic transportGO:00164822340.010
cellular response to antibioticGO:007123640.010
cell type specific apoptotic processGO:00972852680.010
nucleotide biosynthetic processGO:0009165780.010

Dio1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.024
inherited metabolic disorderDOID:65500.024
lipid metabolism disorderDOID:314600.024
nervous system diseaseDOID:86300.019
disease of anatomical entityDOID:700.019
steroid inherited metabolic disorderDOID:170100.012
organ system cancerDOID:005068600.012
cancerDOID:16200.012
disease of cellular proliferationDOID:1456600.012