IMP: Integrative Multi-species Prediction

Mus musculus

206 known processes

Eomes

eomesodermin homolog (Xenopus laevis)

(Aliases: C77258,TBR-2,Tbr2)

Entrez: 13813
Ensembl: ENSMUSG00000032446
UniProtKB: O54839

Process Predictions
Disease Predictions

Eomes biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
epithelial tube morphogenesis	GO:0060562	303	0.867	Mouse
telencephalon development	GO:0021537	186	0.811
neural tube development	GO:0021915	160	0.689	Mouse
epithelial tube formation	GO:0072175	130	0.687	Mouse
tube formation	GO:0035148	140	0.562	Mouse
regionalization	GO:0003002	337	0.560
neural tube formation	GO:0001841	108	0.537	Mouse
formation of primary germ layer	GO:0001704	77	0.536
forebrain development	GO:0030900	302	0.524
digestive tract morphogenesis	GO:0048546	147	0.522
stem cell development	GO:0048864	219	0.510
mesoderm morphogenesis	GO:0048332	64	0.446
embryonic epithelial tube formation	GO:0001838	130	0.437	Mouse
sensory organ morphogenesis	GO:0090596	242	0.435	Mouse
mesoderm development	GO:0007498	100	0.421
embryonic organ morphogenesis	GO:0048562	276	0.397	Mouse
neural tube closure	GO:0001843	90	0.377	Mouse
appendage morphogenesis	GO:0035107	149	0.373	Mouse
primary neural tube formation	GO:0014020	95	0.333	Mouse
camera type eye development	GO:0043010	266	0.313	Mouse
digestive tract development	GO:0048565	190	0.303
regulation of wnt signaling pathway	GO:0030111	123	0.292	Mouse
embryonic limb morphogenesis	GO:0030326	126	0.290	Mouse
mesenchyme morphogenesis	GO:0072132	32	0.287	Mouse
morphogenesis of a branching structure	GO:0001763	203	0.284	Mouse
limb development	GO:0060173	166	0.284	Mouse
determination of left right asymmetry in nervous system	GO:0035545	1	0.280
digestive system development	GO:0055123	200	0.267
diencephalon development	GO:0021536	63	0.257	Mouse
gastrulation	GO:0007369	116	0.251
bmp signaling pathway	GO:0030509	93	0.244	Mouse
cell fate commitment	GO:0045165	210	0.237
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.230
erythrocyte differentiation	GO:0030218	88	0.230
regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity	GO:0031585	2	0.229
morphogenesis of embryonic epithelium	GO:0016331	159	0.227	Mouse
leukocyte differentiation	GO:0002521	342	0.225
odontogenesis of dentin containing tooth	GO:0042475	66	0.220	Mouse
developmental growth involved in morphogenesis	GO:0060560	138	0.216	Mouse
embryonic skeletal system development	GO:0048706	120	0.209	Mouse
olfactory lobe development	GO:0021988	32	0.204
somitogenesis	GO:0001756	69	0.202	Mouse
stem cell maintenance	GO:0019827	130	0.197
regulation of cell activation	GO:0050865	289	0.194	Mouse
respiratory system development	GO:0060541	190	0.191	Mouse
stem cell differentiation	GO:0048863	268	0.191
protein localization to nucleus	GO:0034504	121	0.188
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.187	Mouse
heart morphogenesis	GO:0003007	178	0.186	Mouse
adaptive immune response	GO:0002250	155	0.178	Mouse
regulation of osteoblast differentiation	GO:0045667	67	0.175
tendon formation	GO:0035992	4	0.174
branching morphogenesis of an epithelial tube	GO:0048754	159	0.173	Mouse
lymphocyte mediated immunity	GO:0002449	139	0.171	Mouse
forebrain regionalization	GO:0021871	25	0.170
tendon cell differentiation	GO:0035990	4	0.164
axonogenesis	GO:0007409	274	0.163	Mouse
renal system development	GO:0072001	225	0.161	Mouse
tube closure	GO:0060606	91	0.152	Mouse
positive regulation of nervous system development	GO:0051962	221	0.152
response to growth factor	GO:0070848	198	0.152	Mouse
mammary gland morphogenesis	GO:0060443	54	0.151	Mouse
limb morphogenesis	GO:0035108	149	0.150	Mouse
regulation of neuron differentiation	GO:0045664	281	0.149
mesoderm formation	GO:0001707	62	0.147
negative regulation of neuron death	GO:1901215	98	0.143
regulation of neuron apoptotic process	GO:0043523	122	0.136
gland development	GO:0048732	330	0.135	Mouse
positive regulation of neuron differentiation	GO:0045666	141	0.133
positive regulation of cell morphogenesis involved in differentiation	GO:0010770	72	0.133
myeloid cell differentiation	GO:0030099	233	0.132
mesendoderm development	GO:0048382	3	0.131	Zebrafish
divalent inorganic cation transport	GO:0072511	178	0.129
interferon gamma production	GO:0032609	67	0.129
cellular amino acid metabolic process	GO:0006520	103	0.127
chemotaxis	GO:0006935	247	0.126	Mouse
mesenchyme development	GO:0060485	152	0.126
cell fate specification	GO:0001708	72	0.125
cardiac chamber morphogenesis	GO:0003206	93	0.124	Mouse
placenta development	GO:0001890	140	0.123
regulation of glial cell differentiation	GO:0045685	41	0.122
leukocyte activation involved in immune response	GO:0002366	126	0.122
skeletal system development	GO:0001501	356	0.121	Mouse
regulation of defense response	GO:0031347	233	0.118
regulation of ossification	GO:0030278	112	0.118
oocyte construction	GO:0007308	2	0.117
negative regulation of prostatic bud formation	GO:0060686	4	0.117
endocardial cushion development	GO:0003197	26	0.115	Mouse
response to molecule of bacterial origin	GO:0002237	143	0.115
sensory perception	GO:0007600	245	0.115	Mouse
regulation of stem cell differentiation	GO:2000736	50	0.115
t cell differentiation	GO:0030217	174	0.115
positive regulation of protein modification process	GO:0031401	299	0.114	Mouse
t cell activation	GO:0042110	289	0.114
epithelial to mesenchymal transition	GO:0001837	47	0.113
somite rostral caudal axis specification	GO:0032525	13	0.112	Mouse
cell type specific apoptotic process	GO:0097285	268	0.111	Mouse
angiogenesis	GO:0001525	201	0.110	Mouse
cytokine production	GO:0001816	319	0.109
striated muscle tissue development	GO:0014706	293	0.109
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry	GO:1900094	2	0.109
mesenchymal cell proliferation involved in ureter development	GO:0072198	4	0.108	Mouse
neuron projection guidance	GO:0097485	141	0.106	Mouse
regulation of membrane potential	GO:0042391	192	0.105
nodal signaling pathway involved in determination of left right asymmetry	GO:0038107	2	0.104
gonad morphogenesis	GO:0035262	1	0.103
chondrocyte differentiation	GO:0002062	72	0.103
kidney development	GO:0001822	213	0.102
cell fate determination	GO:0001709	32	0.102	Mouse
endoderm formation	GO:0001706	20	0.102
positive regulation of rhodopsin gene expression	GO:0045872	2	0.101
negative regulation of cell development	GO:0010721	169	0.101	Mouse
single organism cell adhesion	GO:0098602	156	0.101	Mouse
cellular response to growth factor stimulus	GO:0071363	197	0.100	Mouse
cation homeostasis	GO:0055080	212	0.100
olfactory nerve development	GO:0021553	3	0.099
regulation of t cell activation	GO:0050863	170	0.099
positive regulation of interferon gamma production	GO:0032729	39	0.098
motor neuron migration	GO:0097475	4	0.098
regulation of gliogenesis	GO:0014013	50	0.096
neuron death	GO:0070997	154	0.096
mapk cascade	GO:0000165	281	0.096	Mouse
trophectodermal cell differentiation	GO:0001829	21	0.095
cellular response to biotic stimulus	GO:0071216	92	0.095
stimulatory c type lectin receptor signaling pathway	GO:0002223	2	0.095
oocyte axis specification	GO:0007309	2	0.095
positive regulation of t cell activation	GO:0050870	101	0.094
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.093	Mouse
hindbrain development	GO:0030902	128	0.093	Mouse
single organismal cell cell adhesion	GO:0016337	131	0.093	Mouse
pallium development	GO:0021543	120	0.091
mesenchymal cell differentiation	GO:0048762	107	0.088
inflammatory response	GO:0006954	244	0.087
positive regulation of nucleocytoplasmic transport	GO:0046824	30	0.087
regulation of intracellular transport	GO:0032386	159	0.086
regulation of reactive oxygen species biosynthetic process	GO:1903426	2	0.086
appendage development	GO:0048736	166	0.086	Mouse
midgut development	GO:0007494	4	0.086
epithelial cell proliferation	GO:0050673	174	0.085	Mouse
cardiocyte differentiation	GO:0035051	87	0.084
cell surface pattern recognition receptor signaling pathway	GO:0002752	2	0.084
positive regulation of reactive oxygen species metabolic process	GO:2000379	11	0.084
regulation of leukocyte mediated immunity	GO:0002703	104	0.084	Mouse
segmentation	GO:0035282	93	0.084	Mouse
embryonic appendage morphogenesis	GO:0035113	126	0.082	Mouse
deltoid tuberosity development	GO:0035993	3	0.082
immune effector process	GO:0002252	321	0.082
ureteric bud morphogenesis	GO:0060675	62	0.080
peripheral nervous system neuron axonogenesis	GO:0048936	3	0.079
biomineral tissue development	GO:0031214	64	0.078	Mouse
endoderm development	GO:0007492	45	0.078
cardiac septum development	GO:0003279	59	0.078	Mouse
axial mesoderm development	GO:0048318	8	0.077
regulation of astrocyte differentiation	GO:0048710	20	0.077
mesenchymal cell development	GO:0014031	93	0.076
regulation of protein localization	GO:0032880	231	0.076
epithelial cell development	GO:0002064	159	0.074
skeletal system morphogenesis	GO:0048705	203	0.074	Mouse
positive regulation of lymphocyte activation	GO:0051251	140	0.074	Mouse
visceral motor neuron differentiation	GO:0021524	3	0.073	Mouse
defense response to other organism	GO:0098542	197	0.073
leukocyte mediated immunity	GO:0002443	174	0.072	Mouse
epithelial cell differentiation involved in kidney development	GO:0035850	23	0.072
lens development in camera type eye	GO:0002088	62	0.071
regulation of myotube differentiation	GO:0010830	62	0.071	Mouse
morphogenesis of a branching epithelium	GO:0061138	193	0.071	Mouse
regulation of inflammatory response	GO:0050727	147	0.070
forebrain neuron fate commitment	GO:0021877	13	0.070	Mouse
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry	GO:1900164	2	0.070
spinal cord development	GO:0021510	81	0.070	Mouse
cytoplasmic transport	GO:0016482	234	0.069
forebrain neuron differentiation	GO:0021879	52	0.069	Mouse
developmental maturation	GO:0021700	193	0.069	Mouse
metanephros development	GO:0001656	79	0.068
engulfment of apoptotic cell	GO:0043652	3	0.068
dna metabolic process	GO:0006259	303	0.067	Mouse
cell adhesion	GO:0007155	329	0.067	Mouse
sensory system development	GO:0048880	3	0.067
nerve development	GO:0021675	67	0.067	Mouse
lens morphogenesis in camera type eye	GO:0002089	24	0.067
negative regulation of neuron apoptotic process	GO:0043524	92	0.066
regulation of organ morphogenesis	GO:2000027	144	0.066	Mouse
central nervous system neuron development	GO:0021954	67	0.065
regulation of homeostatic process	GO:0032844	182	0.065
inner ear receptor cell differentiation	GO:0060113	61	0.065
positive regulation of cell migration	GO:0030335	109	0.065
endodermal cell fate specification	GO:0001714	4	0.064
cell activation involved in immune response	GO:0002263	126	0.064
activation of immune response	GO:0002253	138	0.064
embryonic heart tube morphogenesis	GO:0003143	51	0.064	Mouse
regulation of bmp signaling pathway	GO:0030510	60	0.063
midbrain hindbrain boundary morphogenesis	GO:0021555	4	0.063
embryonic digit morphogenesis	GO:0042733	56	0.063	Mouse
divalent metal ion transport	GO:0070838	172	0.063
neuron apoptotic process	GO:0051402	142	0.063
negative regulation of reproductive process	GO:2000242	31	0.062
germ cell development	GO:0007281	185	0.062
leukocyte proliferation	GO:0070661	172	0.061
maintenance of location	GO:0051235	89	0.061
glial cell differentiation	GO:0010001	131	0.061
myotube differentiation	GO:0014902	105	0.061	Mouse
muscle tissue development	GO:0060537	308	0.060
regulation of vesicle mediated transport	GO:0060627	139	0.060
negative regulation of growth	GO:0045926	99	0.060
positive regulation of lymphocyte mediated immunity	GO:0002708	62	0.060	Mouse
negative regulation of cellular component organization	GO:0051129	194	0.059	Mouse
retina development in camera type eye	GO:0060041	119	0.059
regulation of cytokine production	GO:0001817	266	0.059
positive regulation of stem cell differentiation	GO:2000738	23	0.059
mechanoreceptor differentiation	GO:0042490	67	0.058
thyroid stimulating hormone secreting cell differentiation	GO:0060129	4	0.058
endomembrane system organization	GO:0010256	147	0.058
regulation of transferase activity	GO:0051338	263	0.057
endocrine system development	GO:0035270	98	0.057	Mouse
mesonephric tubule morphogenesis	GO:0072171	63	0.057
myeloid cell homeostasis	GO:0002262	114	0.057
myeloid leukocyte differentiation	GO:0002573	119	0.057
immune response regulating cell surface receptor signaling pathway	GO:0002768	80	0.056
cerebral cortex radially oriented cell migration	GO:0021799	31	0.056
innate immune response activating cell surface receptor signaling pathway	GO:0002220	4	0.056
olfactory bulb development	GO:0021772	30	0.056
axial mesodermal cell fate commitment	GO:0048322	1	0.056
alpha beta t cell activation	GO:0046631	91	0.056
regulation of mapk cascade	GO:0043408	248	0.056	Mouse
actin cytoskeleton organization	GO:0030036	220	0.055
axial mesodermal cell fate specification	GO:0048327	1	0.054
synaptic transmission	GO:0007268	329	0.053
hematopoietic progenitor cell differentiation	GO:0002244	143	0.053
cell differentiation in spinal cord	GO:0021515	53	0.053	Mouse
negative regulation of cell proliferation	GO:0008285	296	0.053
positive regulation of cell development	GO:0010720	237	0.053
transition metal ion homeostasis	GO:0055076	54	0.052
neuron migration	GO:0001764	122	0.052	Mouse
negative regulation of myoblast differentiation	GO:0045662	18	0.052
membrane invagination	GO:0010324	17	0.052
regulation of ion transport	GO:0043269	215	0.052
embryonic skeletal system morphogenesis	GO:0048704	91	0.051	Mouse
central nervous system segmentation	GO:0035283	3	0.051
brain segmentation	GO:0035284	3	0.051
cranial nerve development	GO:0021545	41	0.051	Mouse
embryonic viscerocranium morphogenesis	GO:0048703	8	0.051
lymphocyte differentiation	GO:0030098	242	0.051
ureter urothelium development	GO:0072190	3	0.050
wnt signaling pathway	GO:0016055	188	0.050	Mouse
positive regulation of dna endoreduplication	GO:0032877	2	0.050
metal ion homeostasis	GO:0055065	189	0.050
organonitrogen compound catabolic process	GO:1901565	264	0.050
regulation of neuron death	GO:1901214	134	0.050
cerebral cortex development	GO:0021987	86	0.050
muscle tissue morphogenesis	GO:0060415	53	0.050	Mouse
regulation of cellular amino acid metabolic process	GO:0006521	5	0.050
head morphogenesis	GO:0060323	34	0.049	Mouse
regulation of rhodopsin gene expression	GO:0007468	3	0.049
regulation of muscle tissue development	GO:1901861	97	0.049	Mouse
regulation of protein targeting	GO:1903533	61	0.049
ribonucleoside metabolic process	GO:0009119	245	0.049
ear morphogenesis	GO:0042471	118	0.048	Mouse
negative regulation of cellular protein metabolic process	GO:0032269	247	0.048
regulation of binding	GO:0051098	111	0.048
dna endoreduplication	GO:0042023	4	0.048
positive regulation of branching involved in lung morphogenesis	GO:0061047	4	0.048
respiratory tube development	GO:0030323	167	0.048	Mouse
pituitary gland development	GO:0021983	38	0.048	Mouse
regulation of skeletal muscle fiber development	GO:0048742	36	0.048
regulation of neuron projection development	GO:0010975	169	0.047	Mouse
gliogenesis	GO:0042063	141	0.047
visual perception	GO:0007601	52	0.047
connective tissue development	GO:0061448	179	0.047
lymphocyte proliferation	GO:0046651	164	0.047
negative regulation of phosphorus metabolic process	GO:0010563	184	0.047
dephosphorylation	GO:0016311	129	0.047
lateral line system development	GO:0048925	1	0.047
blastocyst formation	GO:0001825	33	0.047
muscle cell differentiation	GO:0042692	261	0.047	Mouse
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.046
odontogenesis	GO:0042476	78	0.046	Mouse
positive regulation of osteoblast differentiation	GO:0045669	34	0.046
germ line stem cell division	GO:0042078	2	0.045
cell differentiation involved in kidney development	GO:0061005	33	0.045
regulation of cellular ketone metabolic process	GO:0010565	66	0.045
blastocyst development	GO:0001824	80	0.045
glycoprotein metabolic process	GO:0009100	116	0.045
innate immune response	GO:0045087	157	0.045
peptidyl tyrosine modification	GO:0018212	145	0.045
negative regulation of molecular function	GO:0044092	258	0.044
regulation of cell motility	GO:2000145	236	0.044
nephron tubule morphogenesis	GO:0072078	68	0.044
positive regulation of protein phosphorylation	GO:0001934	242	0.044	Mouse
heart valve morphogenesis	GO:0003179	21	0.044	Mouse
cation transport	GO:0006812	399	0.044
cell maturation	GO:0048469	127	0.044	Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.043	Mouse
response to molecule of fungal origin	GO:0002238	4	0.043
retrograde vesicle mediated transport golgi to er	GO:0006890	1	0.043
calcium ion transport	GO:0006816	159	0.043
cellular ketone metabolic process	GO:0042180	84	0.043
mesodermal cell differentiation	GO:0048333	22	0.043
cerebral cortex cell migration	GO:0021795	44	0.043
heart trabecula morphogenesis	GO:0061384	26	0.043
cardiac ventricle development	GO:0003231	83	0.042	Mouse
regulation of interferon gamma production	GO:0032649	57	0.042
positive regulation of reactive oxygen species biosynthetic process	GO:1903428	2	0.042
neural tube patterning	GO:0021532	43	0.041
blastocyst growth	GO:0001832	23	0.040
production of molecular mediator of immune response	GO:0002440	103	0.040	Mouse
positive regulation of intracellular protein transport	GO:0090316	42	0.040
embryonic heart tube anterior posterior pattern specification	GO:0035054	3	0.040
response to acid chemical	GO:0001101	111	0.040	Mouse
renal system process	GO:0003014	48	0.040
reactive nitrogen species metabolic process	GO:2001057	0	0.040
negative regulation of protein phosphorylation	GO:0001933	126	0.040
regulation of innate immune response	GO:0045088	91	0.040
embryonic placenta development	GO:0001892	98	0.040
cell division	GO:0051301	120	0.040
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.040
negative regulation of osteoblast differentiation	GO:0045668	30	0.040
developmental induction	GO:0031128	34	0.039
positive regulation of glial cell differentiation	GO:0045687	21	0.039
regulation of dna endoreduplication	GO:0032875	3	0.039
bone development	GO:0060348	120	0.039	Mouse
maintenance of apical basal cell polarity	GO:0035090	3	0.039
protein localization to organelle	GO:0033365	185	0.039
positive regulation of lymphocyte proliferation	GO:0050671	70	0.039
negative regulation of phosphate metabolic process	GO:0045936	184	0.039
cellular response to acid chemical	GO:0071229	68	0.039	Mouse
glomerulus morphogenesis	GO:0072102	10	0.039
protein maturation	GO:0051604	176	0.038
fat cell differentiation	GO:0045444	160	0.038
immune response activating signal transduction	GO:0002757	116	0.038
cellular response to lipopolysaccharide	GO:0071222	77	0.038
female gamete generation	GO:0007292	74	0.038
positive regulation of bmp signaling pathway	GO:0030513	23	0.038
positive regulation of cytoplasmic transport	GO:1903651	40	0.037
ossification	GO:0001503	216	0.037
urogenital system development	GO:0001655	261	0.037	Mouse
trachea formation	GO:0060440	3	0.037
regulation of cellular component biogenesis	GO:0044087	181	0.037	Mouse
regulation of reproductive process	GO:2000241	66	0.037
axon guidance	GO:0007411	141	0.037	Mouse
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.037
multicellular organismal homeostasis	GO:0048871	164	0.037
t cell differentiation involved in immune response	GO:0002292	30	0.037
homeostasis of number of cells	GO:0048872	210	0.037
positive regulation of programmed cell death	GO:0043068	218	0.037
cardiac chamber development	GO:0003205	108	0.037	Mouse
establishment of protein localization to organelle	GO:0072594	118	0.037
intraspecies interaction between organisms	GO:0051703	21	0.036	Mouse
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.036
metanephric loop of henle development	GO:0072236	4	0.036
central nervous system neuron differentiation	GO:0021953	162	0.036
positive regulation of tendon cell differentiation	GO:2001051	1	0.036
regulation of receptor activity	GO:0010469	41	0.036
membrane organization	GO:0061024	245	0.036
response to oxygen levels	GO:0070482	62	0.036
organic acid transport	GO:0015849	101	0.036
sensory perception of sound	GO:0007605	97	0.036	Mouse
regulation of cell migration	GO:0030334	219	0.036
embryonic axis specification	GO:0000578	30	0.036	Mouse
endodermal cell fate commitment	GO:0001711	12	0.035
regulation of chondrocyte differentiation	GO:0032330	33	0.035
negative regulation of protein metabolic process	GO:0051248	282	0.035
detection of chemical stimulus involved in sensory perception of smell	GO:0050911	4	0.035
cardiac ventricle morphogenesis	GO:0003208	50	0.035	Mouse
cellular chemical homeostasis	GO:0055082	215	0.035
oocyte differentiation	GO:0009994	35	0.035
determination of digestive tract left right asymmetry	GO:0071907	1	0.035
inner cell mass cell proliferation	GO:0001833	15	0.035
leukocyte migration	GO:0050900	124	0.034	Mouse
action potential	GO:0001508	78	0.034
cerebral cortex neuron differentiation	GO:0021895	19	0.034
cell killing	GO:0001906	67	0.034
regulation of secretion	GO:0051046	274	0.034
positive regulation of gliogenesis	GO:0014015	27	0.034
regulation of epithelial cell proliferation	GO:0050678	141	0.034	Mouse
regulation of epithelial to mesenchymal transition	GO:0010717	22	0.034
actin filament organization	GO:0007015	113	0.034
regulation of cell adhesion	GO:0030155	154	0.034	Mouse
nucleotide catabolic process	GO:0009166	217	0.033
reactive oxygen species biosynthetic process	GO:1903409	8	0.033
regulation of smoothened signaling pathway	GO:0008589	58	0.033
cell proliferation in forebrain	GO:0021846	30	0.033
regulation of cytoplasmic transport	GO:1903649	112	0.033
regulation of hydrolase activity	GO:0051336	246	0.033
gonad development	GO:0008406	141	0.033
positive regulation of protein import into nucleus	GO:0042307	26	0.033
negative regulation of immune system process	GO:0002683	209	0.033
erk1 and erk2 cascade	GO:0070371	77	0.033
cellular nitrogen compound catabolic process	GO:0044270	280	0.033
regulation of interleukin 1 alpha production	GO:0032650	4	0.033
negative regulation of intracellular signal transduction	GO:1902532	167	0.033
epithalamus development	GO:0021538	2	0.032
positive regulation of natural killer cell mediated immunity	GO:0002717	16	0.032
dicarboxylic acid biosynthetic process	GO:0043650	5	0.032
myoblast differentiation	GO:0045445	52	0.032	Mouse
positive regulation of cell motility	GO:2000147	116	0.032
multi organism behavior	GO:0051705	62	0.032	Mouse
positive regulation of defense response	GO:0031349	124	0.032
regulation of apoptotic signaling pathway	GO:2001233	197	0.032
regulation of leukocyte differentiation	GO:1902105	159	0.032
positive regulation of sequence specific dna binding transcription factor activity	GO:0051091	68	0.032
corticotropin hormone secreting cell differentiation	GO:0060128	3	0.032
regulation of kinase activity	GO:0043549	249	0.032
posttranscriptional regulation of gene expression	GO:0010608	155	0.031
regulation of protein import into nucleus	GO:0042306	52	0.031
embryonic skeletal joint development	GO:0072498	13	0.031
epidermis development	GO:0008544	187	0.031
cellular response to molecule of bacterial origin	GO:0071219	83	0.031
regulation of cellular catabolic process	GO:0031329	242	0.031
regulation of organ formation	GO:0003156	34	0.031	Mouse
branching involved in ureteric bud morphogenesis	GO:0001658	56	0.031
reactive oxygen species metabolic process	GO:0072593	84	0.031
regulation of lymphocyte activation	GO:0051249	240	0.031	Mouse
telencephalon cell migration	GO:0022029	55	0.031
negative regulation of nervous system development	GO:0051961	156	0.031	Mouse
cartilage development	GO:0051216	140	0.031
cellular response to organonitrogen compound	GO:0071417	145	0.031
nitrogen compound transport	GO:0071705	271	0.031
regulation of nucleocytoplasmic transport	GO:0046822	73	0.031
cell cell signaling involved in cell fate commitment	GO:0045168	35	0.031
sensory perception of light stimulus	GO:0050953	54	0.031
cellular amine metabolic process	GO:0044106	44	0.031
cell fate commitment involved in formation of primary germ layer	GO:0060795	26	0.031
hypothalamus development	GO:0021854	16	0.030
single organism nuclear import	GO:1902593	95	0.030
regulation of protein kinase activity	GO:0045859	232	0.030
regulation of myeloid cell differentiation	GO:0045637	96	0.030
negative regulation of ossification	GO:0030279	49	0.030
positive regulation of immune effector process	GO:0002699	107	0.030	Mouse
skin development	GO:0043588	220	0.030
response to lipopolysaccharide	GO:0032496	128	0.030
muscle cell development	GO:0055001	133	0.030	Mouse
endocardial cushion morphogenesis	GO:0003203	18	0.030	Mouse
skeletal muscle organ development	GO:0060538	163	0.030
kidney mesenchyme morphogenesis	GO:0072131	4	0.030
smad protein signal transduction	GO:0060395	21	0.030	Mouse
transmembrane transport	GO:0055085	412	0.030
columnar cuboidal epithelial cell differentiation	GO:0002065	82	0.030
forebrain generation of neurons	GO:0021872	63	0.030	Mouse
protein ubiquitination	GO:0016567	171	0.029
negative regulation of phosphorylation	GO:0042326	166	0.029
positive regulation of mapk cascade	GO:0043410	170	0.029	Mouse
transdifferentiation	GO:0060290	1	0.029
cytokine biosynthetic process	GO:0042089	68	0.029
mesodermal cell migration	GO:0008078	4	0.029
photoreceptor cell development	GO:0042461	40	0.029
response to fibroblast growth factor	GO:0071774	47	0.029	Mouse
multi multicellular organism process	GO:0044706	109	0.029	Mouse
regulation of cellular amine metabolic process	GO:0033238	20	0.029
motor neuron axon guidance	GO:0008045	26	0.029
embryonic skeletal joint morphogenesis	GO:0060272	11	0.029
spinal cord motor neuron migration	GO:0097476	4	0.029
neuroblast differentiation	GO:0014016	2	0.029
mitotic cell cycle process	GO:1903047	159	0.029
positive regulation of organelle organization	GO:0010638	128	0.028
nephron tubule development	GO:0072080	84	0.028
regulation of protein localization to nucleus	GO:1900180	60	0.028
left lung morphogenesis	GO:0060460	3	0.028
negative regulation of protein modification process	GO:0031400	163	0.028
regulation of endopeptidase activity	GO:0052548	89	0.028
regulation of cytokine biosynthetic process	GO:0042035	59	0.028
cardiac septum morphogenesis	GO:0060411	46	0.028	Mouse
kidney epithelium development	GO:0072073	121	0.028
negative regulation of wnt signaling pathway	GO:0030178	73	0.028	Mouse
positive regulation of cellular amine metabolic process	GO:0033240	5	0.028
microtubule based movement	GO:0007018	84	0.028
regulation of tumor necrosis factor production	GO:0032680	49	0.028
response to radiation	GO:0009314	165	0.027
ectoderm formation	GO:0001705	3	0.027
cellular protein complex assembly	GO:0043623	116	0.027	Mouse
regulation of b cell activation	GO:0050864	81	0.027	Mouse
alpha amino acid metabolic process	GO:1901605	59	0.027
skeletal muscle fiber development	GO:0048741	58	0.027
regulation of tumor necrosis factor superfamily cytokine production	GO:1903555	50	0.027
carboxylic acid transport	GO:0046942	100	0.027
oogenesis	GO:0048477	56	0.027
regulation of granulocyte macrophage colony stimulating factor production	GO:0032645	3	0.027
somatic cell dna recombination	GO:0016444	51	0.027	Mouse
eye photoreceptor cell development	GO:0042462	31	0.027
telencephalon regionalization	GO:0021978	14	0.027
b cell proliferation	GO:0042100	53	0.027
apoptotic signaling pathway	GO:0097190	306	0.027
regulation of striated muscle cell differentiation	GO:0051153	81	0.027	Mouse
granzyme mediated apoptotic signaling pathway	GO:0008626	1	0.027
dendrite development	GO:0016358	115	0.026
renal tubule development	GO:0061326	87	0.026
muscle fiber development	GO:0048747	76	0.026
endothelial cell differentiation	GO:0045446	41	0.026
sequestering of calcium ion	GO:0051208	18	0.026

Eomes disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
physical disorder	DOID:0080015	0.088
disease of anatomical entity	DOID:7	0.060
nervous system disease	DOID:863	0.060
cancer	DOID:162	0.037
disease of cellular proliferation	DOID:14566	0.037
sensory system disease	DOID:0050155	0.033
eye and adnexa disease	DOID:1492	0.033

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