Mus musculus

0 known processes

Mthfd1

methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase

(Aliases: Dcs,Mthfd,E430024A07Rik)

Mthfd1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
purine containing compound metabolic processGO:00725213110.265
cellular nitrogen compound catabolic processGO:00442702800.176
cellular amino acid metabolic processGO:00065201030.145
nucleobase containing small molecule metabolic processGO:00550863520.145
glycosyl compound metabolic processGO:19016572460.144
organonitrogen compound biosynthetic processGO:19015661920.142
organic cyclic compound catabolic processGO:19013612950.133
nucleoside metabolic processGO:00091162460.128
nucleoside phosphate metabolic processGO:00067533380.122
ribonucleoside metabolic processGO:00091192450.110
heterocycle catabolic processGO:00467002800.104
aromatic compound catabolic processGO:00194392860.097
purine nucleotide metabolic processGO:00061633020.095
alpha amino acid metabolic processGO:1901605590.089
alpha amino acid biosynthetic processGO:1901607150.087
nucleoside triphosphate metabolic processGO:00091412300.087
nucleoside monophosphate metabolic processGO:0009123850.085
purine nucleoside triphosphate metabolic processGO:00091442260.080
transmembrane transportGO:00550854120.080
purine ribonucleotide metabolic processGO:00091502900.074
oxidation reduction processGO:00551143420.071
nucleotide metabolic processGO:00091173320.069
purine nucleoside metabolic processGO:00422782410.068
ion transmembrane transportGO:00342203610.066
response to oxidative stressGO:00069791230.066
purine ribonucleoside triphosphate metabolic processGO:00092052200.062
ribose phosphate metabolic processGO:00196932910.062
ribonucleoside triphosphate metabolic processGO:00091992200.060
ribonucleotide metabolic processGO:00092592910.060
organonitrogen compound catabolic processGO:19015652640.057
cation transportGO:00068123990.056
purine ribonucleoside metabolic processGO:00461282410.054
cellular ketone metabolic processGO:0042180840.053
amine metabolic processGO:0009308450.053
regulation of cellular amino acid metabolic processGO:000652150.053
cellular amino acid biosynthetic processGO:0008652220.052
regulation of cellular ketone metabolic processGO:0010565660.051
positive regulation of cellular amine metabolic processGO:003324050.051
positive regulation of cellular amino acid metabolic processGO:004576430.049
regulation of ion transportGO:00432692150.048
purine nucleoside catabolic processGO:00061522050.048
cellular modified amino acid metabolic processGO:0006575630.045
atp metabolic processGO:0046034750.044
cytokine productionGO:00018163190.041
nucleoside phosphate catabolic processGO:19012922220.040
regulation of transmembrane transportGO:00347621280.040
translationGO:0006412930.039
purine ribonucleoside monophosphate metabolic processGO:0009167800.038
cellular amino acid catabolic processGO:0009063250.037
purine containing compound catabolic processGO:00725232130.036
nucleoside triphosphate catabolic processGO:00091432050.036
regulation of cellular amine metabolic processGO:0033238200.035
inorganic cation transmembrane transportGO:00986622070.035
carboxylic acid biosynthetic processGO:0046394860.035
intrinsic apoptotic signaling pathwayGO:00971931320.035
cellular macromolecule catabolic processGO:00442652060.035
cellular amine metabolic processGO:0044106440.034
nucleotide catabolic processGO:00091662170.034
ribonucleoside monophosphate metabolic processGO:0009161800.033
carbohydrate derivative catabolic processGO:19011362310.033
cation transmembrane transportGO:00986552660.032
purine ribonucleoside catabolic processGO:00461302050.032
posttranscriptional regulation of gene expressionGO:00106081550.032
defecationGO:003042110.032
regulation of defense responseGO:00313472330.032
immune effector processGO:00022523210.030
regulation of translationGO:0006417710.030
regulation of membrane potentialGO:00423911920.030
peptidyl amino acid modificationGO:00181933360.030
ribonucleotide catabolic processGO:00092612080.030
anion transportGO:00068201770.029
cellular response to dna damage stimulusGO:00069742070.029
gland developmentGO:00487323300.029
macromolecule catabolic processGO:00090572810.029
organic acid biosynthetic processGO:0016053860.029
generation of precursor metabolites and energyGO:00060911030.029
inflammatory responseGO:00069542440.029
regulation of organelle organizationGO:00330432890.028
multicellular organismal homeostasisGO:00488711640.028
regulation of ion transmembrane transportGO:00347651190.028
apoptotic signaling pathwayGO:00971903060.028
purine nucleoside monophosphate metabolic processGO:0009126810.028
purine ribonucleotide catabolic processGO:00091542080.028
regulation of cytokine productionGO:00018172660.027
cellular modified amino acid biosynthetic processGO:0042398120.027
intracellular protein transportGO:00068862040.027
positive regulation of cell developmentGO:00107202370.026
regulation of feeding behaviorGO:006025930.025
nucleoside catabolic processGO:00091642060.025
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.025
cytoplasmic transportGO:00164822340.025
membrane organizationGO:00610242450.025
dna metabolic processGO:00062593030.025
positive regulation of cell deathGO:00109422240.024
regulation of hydrolase activityGO:00513362460.024
purine nucleoside triphosphate catabolic processGO:00091462030.024
carbohydrate derivative biosynthetic processGO:19011371830.024
response to organonitrogen compoundGO:00102432460.023
purine nucleotide catabolic processGO:00061952110.023
chemotaxisGO:00069352470.023
small molecule biosynthetic processGO:00442831320.023
nitrogen compound transportGO:00717052710.022
ribonucleoside triphosphate catabolic processGO:00092031990.022
lymphocyte proliferationGO:00466511640.022
cellular metal ion homeostasisGO:00068751510.022
regulation of nucleotide metabolic processGO:00061401690.021
regulation of purine nucleotide metabolic processGO:19005421690.021
anatomical structure homeostasisGO:00602491450.021
small gtpase mediated signal transductionGO:0007264970.021
leukocyte chemotaxisGO:0030595690.021
regulation of cellular response to stressGO:00801351590.021
regulation of transporter activityGO:0032409570.021
organophosphate catabolic processGO:00464342320.020
purine containing compound biosynthetic processGO:0072522700.020
nucleotide biosynthetic processGO:0009165780.020
positive regulation of cytokine productionGO:00018191740.020
small molecule catabolic processGO:0044282710.020
coenzyme metabolic processGO:0006732520.020
endocytosisGO:00068971680.020
carboxylic acid catabolic processGO:0046395510.020
cellular homeostasisGO:00197252400.020
mrna splicing via spliceosomeGO:0000398430.019
sensory perceptionGO:00076002450.019
defense response to other organismGO:00985421970.019
inorganic ion transmembrane transportGO:00986602340.019
ribonucleoside catabolic processGO:00424542060.019
mitochondrion organizationGO:00070051340.019
response to endoplasmic reticulum stressGO:0034976530.019
positive regulation of protein modification processGO:00314012990.019
synaptic transmissionGO:00072683290.019
cellular protein complex assemblyGO:00436231160.019
regulation of metal ion transportGO:00109591060.019
cellular lipid metabolic processGO:00442553230.018
cell adhesionGO:00071553290.018
male gamete generationGO:00482322850.018
cellular chemical homeostasisGO:00550822150.018
divalent inorganic cation homeostasisGO:00725071380.018
response to oxygen radicalGO:0000305160.018
cation homeostasisGO:00550802120.018
cellular ion homeostasisGO:00068731650.018
nucleoside phosphate biosynthetic processGO:1901293790.018
organelle fissionGO:00482851700.017
divalent metal ion transportGO:00708381720.017
regulation of cell motilityGO:20001452360.017
negative regulation of intracellular signal transductionGO:19025321670.017
lymphocyte mediated immunityGO:00024491390.017
locomotory behaviorGO:00076261950.017
calcium ion transportGO:00068161590.017
organophosphate biosynthetic processGO:00904071220.017
ribonucleoside monophosphate catabolic processGO:0009158570.017
metal ion homeostasisGO:00550651890.017
mrna metabolic processGO:0016071840.017
lateral inhibitionGO:004633110.017
regulation of ion transmembrane transporter activityGO:0032412540.017
circulatory system processGO:00030131970.017
tissue homeostasisGO:00018941150.017
cellular response to oxidative stressGO:0034599760.016
regulation of nucleoside metabolic processGO:00091181300.016
dna modificationGO:0006304500.016
cellular aldehyde metabolic processGO:0006081120.016
regulation of response to woundingGO:19030341890.016
purine ribonucleoside triphosphate catabolic processGO:00092071990.016
protein processingGO:00164851630.016
ras protein signal transductionGO:0007265770.016
negative regulation of molecular functionGO:00440922580.016
positive regulation of programmed cell deathGO:00430682180.016
multicellular organismal signalingGO:0035637910.015
regulation of intracellular transportGO:00323861590.015
response to acid chemicalGO:00011011110.015
regulation of mitochondrion organizationGO:0010821270.015
rna catabolic processGO:0006401290.015
epithelial tube morphogenesisGO:00605623030.015
divalent inorganic cation transportGO:00725111780.015
microtubule cytoskeleton organizationGO:00002261570.015
regulation of establishment of protein localizationGO:00702011810.015
intracellular receptor signaling pathwayGO:0030522740.015
negative regulation of cell proliferationGO:00082852960.015
homeostasis of number of cellsGO:00488722100.015
leukocyte migrationGO:00509001240.015
regulation of multi organism processGO:00439001110.015
neuron apoptotic processGO:00514021420.015
innate immune responseGO:00450871570.015
heart processGO:0003015940.015
sulfur compound metabolic processGO:00067901000.014
mapk cascadeGO:00001652810.014
positive regulation of immune effector processGO:00026991070.014
response to organic cyclic compoundGO:00140701980.014
regulation of cellular catabolic processGO:00313292420.014
regulation of neuron differentiationGO:00456642810.014
nucleocytoplasmic transportGO:00069131390.014
positive regulation of apoptotic processGO:00430652170.014
cell type specific apoptotic processGO:00972852680.014
regulation of mrna metabolic processGO:1903311430.014
regulation of cell activationGO:00508652890.014
histone modificationGO:00165701590.014
urogenital system developmentGO:00016552610.014
adult behaviorGO:00305341350.014
response to peptide hormoneGO:00434341270.014
alpha amino acid catabolic processGO:1901606180.014
blood circulationGO:00080151950.014
activation of immune responseGO:00022531380.014
production of molecular mediator of immune responseGO:00024401030.014
rna 3 end processingGO:0031123200.014
sodium ion transportGO:0006814730.014
protein maturationGO:00516041760.014
cellular response to organonitrogen compoundGO:00714171450.014
immune response regulating signaling pathwayGO:00027641250.014
action potentialGO:0001508780.014
cell substrate adhesionGO:00315891300.014
negative regulation of phosphate metabolic processGO:00459361840.013
regulation of inflammatory responseGO:00507271470.013
regulation of response to biotic stimulusGO:0002831380.013
cell activation involved in immune responseGO:00022631260.013
protein oligomerizationGO:0051259670.013
spermatogenesisGO:00072832840.013
germ cell developmentGO:00072811850.013
carbohydrate metabolic processGO:00059752300.013
response to peptideGO:19016521360.013
serine family amino acid metabolic processGO:000906970.013
signal transduction by p53 class mediatorGO:0072331510.013
negative regulation of cellular component organizationGO:00511291940.013
response to extracellular stimulusGO:00099911270.013
positive regulation of protein phosphorylationGO:00019342420.013
endomembrane system organizationGO:00102561470.013
cofactor metabolic processGO:0051186800.013
gtp metabolic processGO:00460391440.013
response to radiationGO:00093141650.013
calcium ion homeostasisGO:00550741270.013
organic hydroxy compound metabolic processGO:19016152030.013
glycoprotein metabolic processGO:00091001160.012
b cell activationGO:00421131610.012
dna repairGO:00062811070.012
leukocyte proliferationGO:00706611720.012
regulation of hormone levelsGO:00108172110.012
myeloid cell differentiationGO:00300992330.012
regulation of oxidative phosphorylationGO:000208260.012
negative regulation of multi organism processGO:0043901680.012
regulation of apoptotic signaling pathwayGO:20012331970.012
neuron deathGO:00709971540.012
folic acid containing compound metabolic processGO:000676030.012
regulation of cytoplasmic transportGO:19036491120.012
regulation of reactive oxygen species biosynthetic processGO:190342620.012
g protein coupled receptor signaling pathwayGO:00071862430.012
positive regulation of nervous system developmentGO:00519622210.012
response to light stimulusGO:00094161350.012
regulation of interleukin 8 productionGO:003267730.012
regulation of protein localizationGO:00328802310.012
rho protein signal transductionGO:0007266320.012
intracellular steroid hormone receptor signaling pathwayGO:0030518290.012
regulation of rna splicingGO:0043484370.012
mrna processingGO:0006397630.012
cellular response to growth factor stimulusGO:00713631970.012
regulation of mrna splicing via spliceosomeGO:0048024320.012
cellular respirationGO:0045333380.011
muscle system processGO:00030121410.011
interleukin 8 productionGO:003263740.011
regulation of system processGO:00440572000.011
cellular response to cytokine stimulusGO:00713451890.011
regulation of mitochondrial translationGO:007012930.011
ameboidal type cell migrationGO:00016671280.011
heart morphogenesisGO:00030071780.011
regulation of reactive oxygen species metabolic processGO:2000377400.011
heart contractionGO:0060047930.011
myeloid leukocyte migrationGO:0097529570.011
cellular calcium ion homeostasisGO:00068741190.011
single organism cell adhesionGO:00986021560.011
regulation of actin filament based processGO:0032970990.011
guanosine containing compound catabolic processGO:19010691440.011
oxidative phosphorylationGO:0006119140.011
cellular response to hormone stimulusGO:00328701500.011
developmental growth involved in morphogenesisGO:00605601380.011
response to reactive oxygen speciesGO:0000302560.011
positive regulation of hydrolase activityGO:00513451480.011
cofactor biosynthetic processGO:0051188410.011
rna splicingGO:0008380540.011
leukocyte activation involved in immune responseGO:00023661260.011
lipid biosynthetic processGO:00086101790.011
regulation of lymphocyte activationGO:00512492400.011
regulation of cell migrationGO:00303342190.011
regulation of cellular component biogenesisGO:00440871810.011
pigment biosynthetic processGO:0046148260.011
cellular response to lipidGO:00713961450.011
development of primary sexual characteristicsGO:00451371430.011
gonad developmentGO:00084061410.011
positive regulation of cell substrate adhesionGO:0010811470.011
humoral immune responseGO:0006959570.011
negative regulation of phosphorylationGO:00423261660.011
reactive oxygen species biosynthetic processGO:190340980.011
negative regulation of immune system processGO:00026832090.011
meiosis iGO:0007127600.011
protein localization to organelleGO:00333651850.011
purine nucleoside monophosphate catabolic processGO:0009128580.011
purine nucleotide biosynthetic processGO:0006164650.011
response to inorganic substanceGO:0010035960.010
regulation of mapk cascadeGO:00434082480.010
negative regulation of phosphorus metabolic processGO:00105631840.010
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.010
cellular divalent inorganic cation homeostasisGO:00725031270.010
positive regulation of cell activationGO:00508671580.010
nucleic acid phosphodiester bond hydrolysisGO:0090305490.010
protein targetingGO:00066051430.010
regulation of anatomical structure sizeGO:00900661780.010
adaptive immune responseGO:00022501550.010
neural precursor cell proliferationGO:00613511210.010
defense response to bacteriumGO:00427421190.010

Mthfd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.040
disease of anatomical entityDOID:700.040
eye and adnexa diseaseDOID:149200.018
sensory system diseaseDOID:005015500.018
eye diseaseDOID:561400.017
central nervous system diseaseDOID:33100.016
neurodegenerative diseaseDOID:128900.015
retinal degenerationDOID:846600.015
retinal diseaseDOID:567900.015
inherited metabolic disorderDOID:65500.013
disease of metabolismDOID:001466700.013