IMP: Integrative Multi-species Prediction

Mus musculus

50 known processes

Npy1r

neuropeptide Y receptor Y1

(Aliases: Npyr,Y1-R)

Entrez: 18166
Ensembl: ENSMUSG00000036437
UniProtKB: Q3V1K5
UniProtKB: Q04573

Process Predictions
Disease Predictions

Npy1r biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
g protein coupled receptor signaling pathway	GO:0007186	243	0.951
adenylate cyclase modulating g protein coupled receptor signaling pathway	GO:0007188	54	0.930	Mouse
hexose metabolic process	GO:0019318	98	0.870
blood circulation	GO:0008015	195	0.867
synaptic transmission	GO:0007268	329	0.840
neuropeptide signaling pathway	GO:0007218	19	0.819
glucose metabolic process	GO:0006006	92	0.818
regulation of secretion	GO:0051046	274	0.783	Rat
acid secretion	GO:0046717	33	0.765	Mouse
regulation of hormone levels	GO:0010817	211	0.763	Mouse Rat
response to organic cyclic compound	GO:0014070	198	0.757	Mouse Rat
neuron migration	GO:0001764	122	0.729	Mouse
cellular chemical homeostasis	GO:0055082	215	0.712	Rat
circulatory system process	GO:0003013	197	0.710
regulation of blood pressure	GO:0008217	93	0.706
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger	GO:0007187	55	0.706	Mouse
regulation of cellular ketone metabolic process	GO:0010565	66	0.692
cytokine production	GO:0001816	319	0.674
cellular ketone metabolic process	GO:0042180	84	0.671
inflammatory response	GO:0006954	244	0.642
transmembrane transport	GO:0055085	412	0.640
divalent inorganic cation homeostasis	GO:0072507	138	0.639	Rat
organic hydroxy compound transport	GO:0015850	93	0.633
phospholipase c activating g protein coupled receptor signaling pathway	GO:0007200	26	0.597	Mouse
peptide hormone secretion	GO:0030072	109	0.586
calcium ion homeostasis	GO:0055074	127	0.562	Rat
action potential	GO:0001508	78	0.560
glucose homeostasis	GO:0042593	128	0.550
sensory perception of pain	GO:0019233	47	0.545
multicellular organism growth	GO:0035264	161	0.534
regulation of system process	GO:0044057	200	0.517	Rat
hormone metabolic process	GO:0042445	86	0.506	Mouse
regulation of cellular amine metabolic process	GO:0033238	20	0.506
regulation of cell motility	GO:2000145	236	0.502
positive regulation of kinase activity	GO:0033674	155	0.495
ion transmembrane transport	GO:0034220	361	0.488
monosaccharide metabolic process	GO:0005996	106	0.484
small gtpase mediated signal transduction	GO:0007264	97	0.479
cellular calcium ion homeostasis	GO:0006874	119	0.471	Rat
neuron death	GO:0070997	154	0.465
carbohydrate metabolic process	GO:0005975	230	0.455
cellular homeostasis	GO:0019725	240	0.455	Rat
forebrain development	GO:0030900	302	0.454	Mouse
cellular amino acid metabolic process	GO:0006520	103	0.446
regulation of kinase activity	GO:0043549	249	0.438
response to pain	GO:0048265	26	0.419	Mouse
regulation of secretion by cell	GO:1903530	249	0.418	Rat
mapk cascade	GO:0000165	281	0.412
axonogenesis	GO:0007409	274	0.410	Mouse
feeding behavior	GO:0007631	62	0.405
glial cell differentiation	GO:0010001	131	0.395
cellular response to organonitrogen compound	GO:0071417	145	0.392
rhythmic process	GO:0048511	174	0.391	Mouse
cellular amine metabolic process	GO:0044106	44	0.381
cation homeostasis	GO:0055080	212	0.381	Rat
regulation of cellular amino acid metabolic process	GO:0006521	5	0.375
learning or memory	GO:0007611	148	0.369
adenylate cyclase activating g protein coupled receptor signaling pathway	GO:0007189	30	0.365
cognition	GO:0050890	149	0.364
mammary gland lobule development	GO:0061377	22	0.362
amide transport	GO:0042886	138	0.354
regulation of carbohydrate metabolic process	GO:0006109	75	0.351
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.351
leukocyte differentiation	GO:0002521	342	0.349
vascular process in circulatory system	GO:0003018	62	0.345	Rat
anion transport	GO:0006820	177	0.344
nitrogen compound transport	GO:0071705	271	0.339
monocarboxylic acid metabolic process	GO:0032787	191	0.337
response to organonitrogen compound	GO:0010243	246	0.329
regulation of hydrolase activity	GO:0051336	246	0.319
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.313
regulation of cell migration	GO:0030334	219	0.307
cyclic purine nucleotide metabolic process	GO:0052652	43	0.307
gland development	GO:0048732	330	0.303	Mouse
nucleotide metabolic process	GO:0009117	332	0.302
positive regulation of mapk cascade	GO:0043410	170	0.296
peptidyl amino acid modification	GO:0018193	336	0.296
regulation of lymphocyte proliferation	GO:0050670	117	0.292
regulation of feeding behavior	GO:0060259	3	0.284
positive regulation of cyclic nucleotide biosynthetic process	GO:0030804	24	0.284
ribose phosphate biosynthetic process	GO:0046390	59	0.283
regulation of membrane potential	GO:0042391	192	0.283
regulation of insulin receptor signaling pathway	GO:0046626	21	0.281
regulation of protein localization	GO:0032880	231	0.278
regulation of glucose metabolic process	GO:0010906	60	0.272
multicellular organismal signaling	GO:0035637	91	0.270
regulation of inflammatory response	GO:0050727	147	0.262
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway	GO:0051482	4	0.258
negative regulation of blood pressure	GO:0045776	22	0.257
lipid transport	GO:0006869	98	0.252
regulation of cytokine production	GO:0001817	266	0.246
response to nutrient levels	GO:0031667	109	0.244
regulation of lymphocyte activation	GO:0051249	240	0.244
regulation of tube size	GO:0035150	57	0.238	Rat
cellular response to peptide	GO:1901653	92	0.238
transmission of nerve impulse	GO:0019226	76	0.235
regulation of nucleotide metabolic process	GO:0006140	169	0.235
sensory perception	GO:0007600	245	0.228
regulation of leukocyte differentiation	GO:1902105	159	0.227
carbohydrate homeostasis	GO:0033500	128	0.224
negative regulation of phosphorylation	GO:0042326	166	0.224
amino acid transport	GO:0006865	61	0.223
nucleotide biosynthetic process	GO:0009165	78	0.221
regulation of anatomical structure size	GO:0090066	178	0.220	Rat
negative regulation of molecular function	GO:0044092	258	0.219
neuron neuron synaptic transmission	GO:0007270	69	0.218
hormone secretion	GO:0046879	128	0.216	Rat
leukocyte proliferation	GO:0070661	172	0.214
purine ribonucleotide metabolic process	GO:0009150	290	0.214
organic anion transport	GO:0015711	137	0.214
regulation of cellular carbohydrate metabolic process	GO:0010675	75	0.211
cytosolic calcium ion homeostasis	GO:0051480	70	0.210	Rat
positive regulation of cellular amine metabolic process	GO:0033240	5	0.210
purine containing compound metabolic process	GO:0072521	311	0.207
cellular lipid metabolic process	GO:0044255	323	0.206
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.206
pyruvate metabolic process	GO:0006090	28	0.205
response to ammonium ion	GO:0060359	21	0.203
nucleoside phosphate metabolic process	GO:0006753	338	0.202
regulation of leukocyte proliferation	GO:0070663	121	0.201
regulation of cellular catabolic process	GO:0031329	242	0.197
cell adhesion	GO:0007155	329	0.196
ras protein signal transduction	GO:0007265	77	0.194
second messenger mediated signaling	GO:0019932	73	0.194
fatty acid metabolic process	GO:0006631	121	0.194
peptide secretion	GO:0002790	114	0.193
regulation of camp metabolic process	GO:0030814	30	0.190
positive regulation of cytosolic calcium ion concentration	GO:0007204	65	0.188
regulation of neuron apoptotic process	GO:0043523	122	0.186
amine metabolic process	GO:0009308	45	0.185
cyclic nucleotide metabolic process	GO:0009187	59	0.185
response to radiation	GO:0009314	165	0.184
negative regulation of growth	GO:0045926	99	0.183
corticosterone secretion	GO:0035934	3	0.181
regulation of response to wounding	GO:1903034	189	0.181
regulation of ras protein signal transduction	GO:0046578	114	0.180
regulation of reactive oxygen species biosynthetic process	GO:1903426	2	0.180
memory	GO:0007613	58	0.178
carbohydrate derivative biosynthetic process	GO:1901137	183	0.176
blood vessel morphogenesis	GO:0048514	285	0.175
cell growth	GO:0016049	130	0.173
negative regulation of cellular amine metabolic process	GO:0033239	1	0.173
organonitrogen compound biosynthetic process	GO:1901566	192	0.171
lipid biosynthetic process	GO:0008610	179	0.170
organonitrogen compound catabolic process	GO:1901565	264	0.169
negative regulation of cellular carbohydrate metabolic process	GO:0010677	19	0.168
regulation of cell adhesion	GO:0030155	154	0.168
response to growth factor	GO:0070848	198	0.167
circadian rhythm	GO:0007623	114	0.167	Mouse
steroid metabolic process	GO:0008202	119	0.167
negative regulation of cellular protein metabolic process	GO:0032269	247	0.165
organic hydroxy compound metabolic process	GO:1901615	203	0.164
regulation of organelle organization	GO:0033043	289	0.163
response to corticosteroid	GO:0031960	20	0.162	Mouse
positive regulation of transferase activity	GO:0051347	167	0.162
ribonucleotide metabolic process	GO:0009259	291	0.162
peptide transport	GO:0015833	133	0.160
negative regulation of phosphorus metabolic process	GO:0010563	184	0.160
response to steroid hormone	GO:0048545	56	0.158	Mouse Rat
response to insulin	GO:0032868	100	0.157
negative regulation of protein metabolic process	GO:0051248	282	0.156
regulation of purine nucleotide metabolic process	GO:1900542	169	0.156
adenylate cyclase inhibiting g protein coupled receptor signaling pathway	GO:0007193	20	0.154	Mouse
nucleobase containing small molecule metabolic process	GO:0055086	352	0.154
regulation of peptide transport	GO:0090087	91	0.153
drug catabolic process	GO:0042737	2	0.153
camp biosynthetic process	GO:0006171	31	0.153
regulation of mapk cascade	GO:0043408	248	0.152
regulation of action potential	GO:0098900	4	0.151
cellular response to hormone stimulus	GO:0032870	150	0.149
purine nucleotide metabolic process	GO:0006163	302	0.148
polysaccharide metabolic process	GO:0005976	39	0.148
positive regulation of hydrolase activity	GO:0051345	148	0.148
regulation of apoptotic signaling pathway	GO:2001233	197	0.147
rho protein signal transduction	GO:0007266	32	0.146
cation transport	GO:0006812	399	0.146
locomotory behavior	GO:0007626	195	0.145
membrane organization	GO:0061024	245	0.144
learning	GO:0007612	98	0.144
sodium ion transmembrane transport	GO:0035725	49	0.144
oxidation reduction process	GO:0055114	342	0.143
multicellular organismal response to stress	GO:0033555	62	0.143	Mouse
protein kinase c activating g protein coupled receptor signaling pathway	GO:0007205	4	0.142
hormone mediated signaling pathway	GO:0009755	23	0.142
regulation of cell activation	GO:0050865	289	0.141
positive regulation of cell development	GO:0010720	237	0.141
aromatic compound catabolic process	GO:0019439	286	0.140
response to alkaloid	GO:0043279	34	0.140
cell substrate adhesion	GO:0031589	130	0.139
response to cocaine	GO:0042220	14	0.138
organophosphate biosynthetic process	GO:0090407	122	0.138
lipid localization	GO:0010876	126	0.138
digestion	GO:0007586	40	0.137	Mouse
cellular metal ion homeostasis	GO:0006875	151	0.136	Rat
regulation of purine nucleotide catabolic process	GO:0033121	122	0.135
monocarboxylic acid catabolic process	GO:0072329	27	0.134
sequestering of calcium ion	GO:0051208	18	0.134
cellular response to growth factor stimulus	GO:0071363	197	0.132
regulation of cysteine type endopeptidase activity	GO:2000116	65	0.132
purine nucleotide biosynthetic process	GO:0006164	65	0.132
response to peptide hormone	GO:0043434	127	0.132
heat generation	GO:0031649	13	0.132
ossification	GO:0001503	216	0.131
camp metabolic process	GO:0046058	40	0.131
gastric acid secretion	GO:0001696	6	0.130	Mouse
positive regulation of protein modification process	GO:0031401	299	0.130
regulation of corticosterone secretion	GO:2000852	2	0.130
glycerolipid metabolic process	GO:0046486	122	0.129
t cell activation	GO:0042110	289	0.129
cellular carbohydrate metabolic process	GO:0044262	119	0.129
ribose phosphate metabolic process	GO:0019693	291	0.128
calcium ion transport into cytosol	GO:0060402	48	0.126
asymmetric stem cell division	GO:0098722	3	0.126
adult behavior	GO:0030534	135	0.125
regulation of nucleotide biosynthetic process	GO:0030808	34	0.122
response to drug	GO:0042493	75	0.122
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.121
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.121	Rat
positive regulation of protein secretion	GO:0050714	52	0.121
negative regulation of protein phosphorylation	GO:0001933	126	0.121
lateral line system development	GO:0048925	1	0.121
cellular ion homeostasis	GO:0006873	165	0.121	Rat
regulation of vesicle mediated transport	GO:0060627	139	0.120
peptidyl tyrosine modification	GO:0018212	145	0.119
hindbrain development	GO:0030902	128	0.118
calcium ion transport	GO:0006816	159	0.117
regulation of transferase activity	GO:0051338	263	0.116
long term synaptic potentiation	GO:0060291	25	0.116
regulation of neuron death	GO:1901214	134	0.116
response to lipopolysaccharide	GO:0032496	128	0.115
positive regulation of nucleotide biosynthetic process	GO:0030810	26	0.115
organic acid catabolic process	GO:0016054	51	0.114
tissue remodeling	GO:0048771	102	0.113
positive regulation of secretion by cell	GO:1903532	114	0.113
photoreceptor cell differentiation	GO:0046530	52	0.112
sensory organ morphogenesis	GO:0090596	242	0.111
gamma aminobutyric acid signaling pathway	GO:0007214	8	0.110
cellular response to lipid	GO:0071396	145	0.110
regulation of glucocorticoid secretion	GO:2000849	5	0.109
inorganic cation transmembrane transport	GO:0098662	207	0.109
glucose import	GO:0046323	32	0.108
regulation of myeloid cell differentiation	GO:0045637	96	0.107
vasodilation	GO:0042311	28	0.106
fatty acid catabolic process	GO:0009062	25	0.105
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.105
heart process	GO:0003015	94	0.105
nucleoside metabolic process	GO:0009116	246	0.105
insulin receptor signaling pathway	GO:0008286	49	0.104
positive regulation of neuron differentiation	GO:0045666	141	0.103
t cell differentiation	GO:0030217	174	0.103
cardiac muscle tissue development	GO:0048738	130	0.103
cation transmembrane transport	GO:0098655	266	0.102
immune response activating signal transduction	GO:0002757	116	0.101
heterocycle catabolic process	GO:0046700	280	0.101
sodium ion transport	GO:0006814	73	0.101
muscle cell differentiation	GO:0042692	261	0.100
regulation of nucleoside metabolic process	GO:0009118	130	0.099
intracellular protein transport	GO:0006886	204	0.099
monoamine transport	GO:0015844	33	0.098
response to amino acid	GO:0043200	37	0.098
purine containing compound biosynthetic process	GO:0072522	70	0.098
cellular glucan metabolic process	GO:0006073	32	0.098
positive regulation of protein kinase activity	GO:0045860	144	0.098
synapse assembly	GO:0007416	56	0.097
cellular response to acid chemical	GO:0071229	68	0.097
actin cytoskeleton organization	GO:0030036	220	0.097
regulation of gluconeogenesis	GO:0006111	30	0.097
negative regulation of secretion by cell	GO:1903531	54	0.095	Rat
positive regulation of nervous system development	GO:0051962	221	0.094
regulation of muscle system process	GO:0090257	80	0.094
monosaccharide transport	GO:0015749	58	0.094
regulation of lipid transport	GO:0032368	36	0.094
regulation of establishment of protein localization	GO:0070201	181	0.093
carbohydrate transport	GO:0008643	62	0.092
striated muscle contraction	GO:0006941	45	0.092
energy reserve metabolic process	GO:0006112	39	0.091
positive regulation of lymphocyte proliferation	GO:0050671	70	0.090
ribonucleotide biosynthetic process	GO:0009260	59	0.089
regulation of actin filament based process	GO:0032970	99	0.089
positive regulation of nucleotide metabolic process	GO:0045981	114	0.089
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.089
negative regulation of response to wounding	GO:1903035	77	0.089
hexose transport	GO:0008645	56	0.089
canonical wnt signaling pathway	GO:0060070	130	0.088
gtp metabolic process	GO:0046039	144	0.088
oligodendrocyte differentiation	GO:0048709	53	0.088
acylglycerol metabolic process	GO:0006639	55	0.087
endocytosis	GO:0006897	168	0.087
organic cyclic compound catabolic process	GO:1901361	295	0.086
regulation of b cell activation	GO:0050864	81	0.086
associative learning	GO:0008306	61	0.086
regulation of glycogen metabolic process	GO:0070873	13	0.086
positive regulation of apoptotic signaling pathway	GO:2001235	95	0.085
response to endoplasmic reticulum stress	GO:0034976	53	0.085
maintenance of location	GO:0051235	89	0.085
digestive system development	GO:0055123	200	0.084	Mouse
ear development	GO:0043583	200	0.084
regulation of endopeptidase activity	GO:0052548	89	0.083
response to oxidative stress	GO:0006979	123	0.083
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	61	0.083
regulation of neuron differentiation	GO:0045664	281	0.083
exocytosis	GO:0006887	121	0.083
inorganic ion transmembrane transport	GO:0098660	234	0.082
negative regulation of homeostatic process	GO:0032845	71	0.082
positive regulation of secretion	GO:0051047	130	0.082
regulation of defense response	GO:0031347	233	0.081
detection of stimulus	GO:0051606	84	0.080
positive regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043280	36	0.080
regulation of circadian sleep wake cycle sleep	GO:0045187	3	0.079
positive regulation of protein phosphorylation	GO:0001934	242	0.079
regulation of t cell proliferation	GO:0042129	92	0.079
regulation of protein transport	GO:0051223	163	0.078
fear response	GO:0042596	33	0.078
bone resorption	GO:0045453	38	0.078
stem cell development	GO:0048864	219	0.078
cellular response to granulocyte macrophage colony stimulating factor stimulus	GO:0097011	3	0.077
cellular response to peptide hormone stimulus	GO:0071375	92	0.077
regulation of smooth muscle contraction	GO:0006940	22	0.077
positive regulation of cyclic nucleotide metabolic process	GO:0030801	24	0.077
regulation of ion transmembrane transport	GO:0034765	119	0.076
regulation of peptidase activity	GO:0052547	96	0.076
organic acid transport	GO:0015849	101	0.076
glucose transport	GO:0015758	56	0.075
regulation of fatty acid metabolic process	GO:0019217	28	0.075
positive regulation of purine nucleotide biosynthetic process	GO:1900373	26	0.075
positive regulation of ion transport	GO:0043270	65	0.075
innate immune response	GO:0045087	157	0.075
tissue homeostasis	GO:0001894	115	0.074
morphogenesis of a branching structure	GO:0001763	203	0.074
carbohydrate catabolic process	GO:0016052	32	0.074
positive regulation of steroid hormone secretion	GO:2000833	2	0.074
positive regulation of the force of heart contraction by epinephrine norepinephrine	GO:0001997	3	0.074
regulation of cellular component biogenesis	GO:0044087	181	0.073
nucleoside phosphate biosynthetic process	GO:1901293	79	0.073
negative regulation of phosphate metabolic process	GO:0045936	184	0.073
positive regulation of cell migration	GO:0030335	109	0.073
drug metabolic process	GO:0017144	4	0.073
positive regulation of leukocyte proliferation	GO:0070665	73	0.072
gliogenesis	GO:0042063	141	0.072
regulation of systemic arterial blood pressure by norepinephrine epinephrine	GO:0001993	8	0.072
muscle system process	GO:0003012	141	0.072	Rat
lymphocyte differentiation	GO:0030098	242	0.072
embryonic placenta development	GO:0001892	98	0.071
phenol containing compound metabolic process	GO:0018958	60	0.071
divalent metal ion transport	GO:0070838	172	0.071
regulation of monocyte extravasation	GO:2000437	2	0.071
regulation of blood vessel size	GO:0050880	56	0.070	Rat
muscle contraction	GO:0006936	101	0.070	Rat
fat soluble vitamin biosynthetic process	GO:0042362	4	0.069
divalent inorganic cation transport	GO:0072511	178	0.069
positive regulation of organelle organization	GO:0010638	128	0.069
monocyte extravasation	GO:0035696	2	0.068
regulation of circadian rhythm	GO:0042752	58	0.068
positive regulation of cytokine biosynthetic process	GO:0042108	40	0.068
response to acid chemical	GO:0001101	111	0.068
alcohol metabolic process	GO:0006066	116	0.068
positive regulation of sodium ion transport	GO:0010765	13	0.068
anatomical structure homeostasis	GO:0060249	145	0.067
protein kinase b signaling	GO:0043491	74	0.067
regulation of response to drug	GO:2001023	2	0.067
i kappab kinase nf kappab signaling	GO:0007249	85	0.067
purine nucleoside metabolic process	GO:0042278	241	0.066
reactive nitrogen species metabolic process	GO:2001057	0	0.066
regulation of camp biosynthetic process	GO:0030817	25	0.066
positive regulation of muscle contraction	GO:0045933	10	0.066
regulation of purine nucleotide biosynthetic process	GO:1900371	34	0.065
eye photoreceptor cell differentiation	GO:0001754	41	0.065
purine ribonucleoside metabolic process	GO:0046128	241	0.065
positive regulation of cell activation	GO:0050867	158	0.065
immune response activating cell surface receptor signaling pathway	GO:0002429	72	0.065
response to oxygen levels	GO:0070482	62	0.064
negative regulation of cell proliferation	GO:0008285	296	0.064
establishment of tissue polarity	GO:0007164	28	0.064
single organism cell adhesion	GO:0098602	156	0.064
positive regulation of programmed cell death	GO:0043068	218	0.064
glycogen metabolic process	GO:0005977	32	0.064
white fat cell differentiation	GO:0050872	15	0.064
regulation of myeloid leukocyte differentiation	GO:0002761	58	0.063
telencephalon development	GO:0021537	186	0.063
positive regulation of erk1 and erk2 cascade	GO:0070374	47	0.063
cd4 positive alpha beta t cell differentiation	GO:0043367	41	0.063
regulation of cell projection organization	GO:0031344	206	0.063
exogenous drug catabolic process	GO:0042738	1	0.063
cytoplasmic transport	GO:0016482	234	0.063
t cell proliferation	GO:0042098	120	0.063
cellular response to cytokine stimulus	GO:0071345	189	0.063
nucleotide catabolic process	GO:0009166	217	0.062
organic acid biosynthetic process	GO:0016053	86	0.062
digestive tract development	GO:0048565	190	0.062	Mouse
placenta blood vessel development	GO:0060674	31	0.062
small molecule biosynthetic process	GO:0044283	132	0.062
olfactory learning	GO:0008355	2	0.062
ensheathment of neurons	GO:0007272	76	0.062
myeloid cell differentiation	GO:0030099	233	0.062
b cell proliferation	GO:0042100	53	0.061
smooth muscle contraction	GO:0006939	44	0.061	Rat
regulation of protein kinase activity	GO:0045859	232	0.061
renal system process	GO:0003014	48	0.061
cardiac chamber development	GO:0003205	108	0.061
pallium development	GO:0021543	120	0.060
cellular lipid catabolic process	GO:0044242	52	0.060
apoptotic signaling pathway	GO:0097190	306	0.060
central nervous system neuron differentiation	GO:0021953	162	0.059
calcium mediated signaling	GO:0019722	46	0.059
glucan metabolic process	GO:0044042	32	0.059
bone remodeling	GO:0046849	53	0.059
immune response regulating cell surface receptor signaling pathway	GO:0002768	80	0.059
activation of immune response	GO:0002253	138	0.059
protein processing	GO:0016485	163	0.059
body fluid secretion	GO:0007589	53	0.059
potassium ion transmembrane transport	GO:0071805	43	0.058
glycerolipid biosynthetic process	GO:0045017	50	0.058
positive regulation of camp biosynthetic process	GO:0030819	19	0.058
regulation of gtp catabolic process	GO:0033124	113	0.058
intracellular receptor signaling pathway	GO:0030522	74	0.058
protein secretion	GO:0009306	111	0.057
regulation of intracellular transport	GO:0032386	159	0.057
regulation of protein targeting	GO:1903533	61	0.057
release of cytochrome c from mitochondria	GO:0001836	23	0.057
nuclear transport	GO:0051169	139	0.057
response to glucocorticoid	GO:0051384	20	0.057	Mouse
response to food	GO:0032094	17	0.056
endocrine process	GO:0050886	39	0.056
response to estrogen	GO:0043627	24	0.056	Rat
activation of transmembrane receptor protein tyrosine kinase activity	GO:0007171	3	0.056
adrenergic receptor signaling pathway	GO:0071875	13	0.056
placenta development	GO:0001890	140	0.056
cerebral cortex development	GO:0021987	86	0.056
regulation of g protein coupled receptor protein signaling pathway	GO:0008277	37	0.055
regulation of appetite	GO:0032098	12	0.055
protein maturation	GO:0051604	176	0.055
negative regulation of inflammatory response	GO:0050728	61	0.055
neural precursor cell proliferation	GO:0061351	121	0.055
negative regulation of cell activation	GO:0050866	111	0.055
positive regulation of t cell activation	GO:0050870	101	0.055
positive regulation of gtpase activity	GO:0043547	85	0.055
retina development in camera type eye	GO:0060041	119	0.055
cell division	GO:0051301	120	0.054
regulation of interleukin 2 production	GO:0032663	28	0.054
regulation of lipid metabolic process	GO:0019216	118	0.054
regulation of fat cell differentiation	GO:0045598	81	0.054
serotonin transport	GO:0006837	11	0.054
potassium ion transport	GO:0006813	52	0.054
regulation of metal ion transport	GO:0010959	106	0.053
response to decreased oxygen levels	GO:0036293	59	0.053
regulation of protein serine threonine kinase activity	GO:0071900	157	0.053
sequestering of metal ion	GO:0051238	19	0.053
regulation of generation of precursor metabolites and energy	GO:0043467	38	0.053
calcium mediated signaling using intracellular calcium source	GO:0035584	3	0.053
regulation of carbohydrate biosynthetic process	GO:0043255	40	0.053
defense response to other organism	GO:0098542	197	0.052
response to extracellular stimulus	GO:0009991	127	0.052
leukocyte mediated immunity	GO:0002443	174	0.052
regulation of t cell activation	GO:0050863	170	0.052
odontogenesis of dentin containing tooth	GO:0042475	66	0.052
positive regulation of lipid metabolic process	GO:0045834	40	0.052
regulation of long term synaptic potentiation	GO:1900271	4	0.052
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.051
positive regulation of lipid transport	GO:0032370	22	0.051
metal ion homeostasis	GO:0055065	189	0.051	Rat
brown fat cell differentiation	GO:0050873	36	0.051
regulation of hormone secretion	GO:0046883	88	0.050	Rat
positive regulation of heart rate by epinephrine norepinephrine	GO:0001996	4	0.050
multicellular organismal homeostasis	GO:0048871	164	0.050
dopamine receptor signaling pathway	GO:0007212	16	0.050
fat cell differentiation	GO:0045444	160	0.050
regulation of endothelial cell proliferation	GO:0001936	23	0.050
positive regulation of cysteine type endopeptidase activity	GO:2001056	39	0.050
positive regulation of blood circulation	GO:1903524	22	0.050	Rat
negative regulation of systemic arterial blood pressure	GO:0003085	15	0.049
regulation of homeostatic process	GO:0032844	182	0.049
germ cell development	GO:0007281	185	0.049
positive regulation of nitric oxide synthase activity	GO:0051000	2	0.049
negative regulation of protein modification process	GO:0031400	163	0.049
positive regulation of camp metabolic process	GO:0030816	19	0.049
regulation of carbohydrate catabolic process	GO:0043470	12	0.049
establishment of neuroblast polarity	GO:0045200	1	0.049
positive regulation of sequence specific dna binding transcription factor activity	GO:0051091	68	0.049
cytokine biosynthetic process	GO:0042089	68	0.048
cellular response to amino acid stimulus	GO:0071230	29	0.048
generation of precursor metabolites and energy	GO:0006091	103	0.048
neuron apoptotic process	GO:0051402	142	0.048
carboxylic acid catabolic process	GO:0046395	51	0.048
regulation of transforming growth factor beta receptor signaling pathway	GO:0017015	43	0.048
phagocytosis	GO:0006909	66	0.048
regulation of phospholipase c activity	GO:1900274	3	0.048
skeletal system development	GO:0001501	356	0.048
neutral lipid metabolic process	GO:0006638	57	0.048
epithelium migration	GO:0090132	63	0.048
lipid modification	GO:0030258	65	0.048
regulation of antigen receptor mediated signaling pathway	GO:0050854	29	0.047
response to nicotine	GO:0035094	6	0.047
camera type eye development	GO:0043010	266	0.047
positive regulation of nucleoside metabolic process	GO:0045979	91	0.047
t cell receptor signaling pathway	GO:0050852	46	0.047
pigment metabolic process	GO:0042440	32	0.047

Npy1r disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.077
nervous system disease	DOID:863	0.077
central nervous system disease	DOID:331	0.067

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