Mus musculus

23 known processes

Naalad2

N-acetylated alpha-linked acidic dipeptidase 2

(Aliases: NAALADASE2,2700022G20Rik,NAADALASE2,GCPIII,D9Ertd285e,MGC124348,MGC124349)

Naalad2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to growth factor stimulusGO:00713631970.143
negative regulation of tooth mineralizationGO:007017110.122
cell adhesionGO:00071553290.113
response to growth factorGO:00708481980.098
regulation of tooth mineralizationGO:007017020.084
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.081
retinal blood vessel morphogenesisGO:006130430.079
extracellular matrix organizationGO:00301981470.077
extracellular structure organizationGO:00430621480.073
positive regulation of cellular amino acid metabolic processGO:004576430.070
extrinsic apoptotic signaling pathwayGO:00971911260.069
peptidyl amino acid modificationGO:00181933360.068
angiogenesisGO:00015252010.063
stem cell differentiationGO:00488632680.062
negative regulation of cell proliferationGO:00082852960.061
regulation of cellular component biogenesisGO:00440871810.059
muscle system processGO:00030121410.058
camera type eye developmentGO:00430102660.053
negative regulation of apoptotic signaling pathwayGO:20012341040.051
regulation of apoptotic signaling pathwayGO:20012331970.050
blood circulationGO:00080151950.049
positive regulation of cell adhesionGO:0045785800.048
regulation of cell adhesionGO:00301551540.048
regulation of system processGO:00440572000.046
nuclear transportGO:00511691390.045
skeletal system developmentGO:00015013560.045
sa node cell to atrial cardiac muscle cell signallingGO:008601840.045
regulation of organ morphogenesisGO:20000271440.044
cytokine productionGO:00018163190.044
cellular amine metabolic processGO:0044106440.044
cellular ketone metabolic processGO:0042180840.043
peptidyl serine modificationGO:0018209830.043
negative regulation of cellular response to growth factor stimulusGO:0090288460.042
actin cytoskeleton organizationGO:00300362200.041
blood vessel morphogenesisGO:00485142850.041
circulatory system processGO:00030131970.041
apoptotic signaling pathwayGO:00971903060.040
positive regulation of cellular amine metabolic processGO:003324050.040
response to organonitrogen compoundGO:00102432460.039
response to transforming growth factor betaGO:0071559880.038
regulation of muscle system processGO:0090257800.037
regulation of cellular ketone metabolic processGO:0010565660.037
regulation of intracellular protein transportGO:0033157820.037
immune effector processGO:00022523210.037
cell type specific apoptotic processGO:00972852680.037
branching morphogenesis of an epithelial tubeGO:00487541590.037
respiratory system developmentGO:00605411900.036
negative regulation of phosphorus metabolic processGO:00105631840.036
regulation of cell substrate adhesionGO:0010810730.036
cytoplasmic transportGO:00164822340.036
amine metabolic processGO:0009308450.035
positive regulation of cell substrate adhesionGO:0010811470.035
positive regulation of cellular component biogenesisGO:0044089940.035
positive regulation of erk1 and erk2 cascadeGO:0070374470.035
lung developmentGO:00303241640.034
compound eye developmentGO:004874910.032
cellular response to amino acid stimulusGO:0071230290.032
regulation of protein localizationGO:00328802310.031
heart morphogenesisGO:00030071780.031
renal system developmentGO:00720012250.031
urogenital system developmentGO:00016552610.030
odontogenesisGO:0042476780.030
chondroitin sulfate proteoglycan metabolic processGO:0050654200.030
anatomical structure homeostasisGO:00602491450.030
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.029
activation of immune responseGO:00022531380.029
cell substrate adhesionGO:00315891300.029
membrane organizationGO:00610242450.029
regulation of cellular amino acid metabolic processGO:000652150.028
nucleocytoplasmic transportGO:00069131390.028
negative regulation of blood vessel morphogenesisGO:2000181250.028
response to organic cyclic compoundGO:00140701980.027
positive regulation of nervous system developmentGO:00519622210.027
regulation of establishment of protein localizationGO:00702011810.027
fat cell differentiationGO:00454441600.027
regulation of cell projection organizationGO:00313442060.027
nuclear importGO:0051170950.026
small gtpase mediated signal transductionGO:0007264970.026
regulation of wnt signaling pathwayGO:00301111230.026
regulation of mapk cascadeGO:00434082480.026
vegf activated neuropilin signaling pathwayGO:003819020.026
morphogenesis of a branching epitheliumGO:00611381930.026
regulation of cellular amine metabolic processGO:0033238200.026
sensory organ morphogenesisGO:00905962420.025
tissue homeostasisGO:00018941150.025
cellular response to transforming growth factor beta stimulusGO:0071560880.025
cartilage developmentGO:00512161400.025
protein processingGO:00164851630.025
connective tissue developmentGO:00614481790.025
sulfur compound metabolic processGO:00067901000.025
negative regulation of phosphate metabolic processGO:00459361840.024
transforming growth factor beta receptor signaling pathwayGO:0007179710.024
bone developmentGO:00603481200.024
positive regulation of cell deathGO:00109422240.024
regulation of cytoplasmic transportGO:19036491120.024
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.023
regulation of cellular response to growth factor stimulusGO:0090287820.023
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.023
morphogenesis of embryonic epitheliumGO:00163311590.023
dna metabolic processGO:00062593030.023
regulation of cell motilityGO:20001452360.022
positive regulation of protein phosphorylationGO:00019342420.022
negative regulation of cell adhesionGO:0007162450.022
protein oligomerizationGO:0051259670.022
defense response to bacteriumGO:00427421190.022
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512260.022
negative regulation of hydrolase activityGO:0051346710.022
positive regulation of cell projection organizationGO:0031346950.022
organelle assemblyGO:00709251770.022
regulation of intracellular transportGO:00323861590.022
regulation of biomineral tissue developmentGO:0070167330.021
multi multicellular organism processGO:00447061090.021
negative regulation of neuron deathGO:1901215980.021
innate immune responseGO:00450871570.021
sensory perception of mechanical stimulusGO:00509541070.021
morphogenesis of a branching structureGO:00017632030.021
signal transduction in absence of ligandGO:0038034550.021
negative regulation of cell proliferation involved in contact inhibitionGO:006024430.021
cellular amino acid metabolic processGO:00065201030.021
hair follicle developmentGO:0001942850.020
epithelial cell proliferationGO:00506731740.020
negative regulation of phospholipase activityGO:001051940.020
branching involved in salivary gland morphogenesisGO:0060445260.020
positive regulation of growthGO:00459271040.020
positive regulation of protein modification processGO:00314012990.020
negative regulation of phosphorylationGO:00423261660.020
cytokine production involved in immune responseGO:0002367340.020
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.020
regulation of cell morphogenesis involved in differentiationGO:00107691510.019
negative regulation of molecular functionGO:00440922580.019
cardiac muscle contractionGO:0060048320.019
response to amino acidGO:0043200370.019
cellular response to dna damage stimulusGO:00069742070.019
hematopoietic progenitor cell differentiationGO:00022441430.019
establishment or maintenance of cell polarityGO:0007163860.019
trabecula morphogenesisGO:0061383400.019
i kappab kinase nf kappab signalingGO:0007249850.019
lung alveolus developmentGO:0048286450.019
negative regulation of cell motilityGO:2000146610.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.018
single organism nuclear importGO:1902593950.018
production of molecular mediator of immune responseGO:00024401030.018
regulation of peptidase activityGO:0052547960.018
positive regulation of smooth muscle cell migrationGO:001491140.018
cellular response to acid chemicalGO:0071229680.018
inner ear morphogenesisGO:00424721010.018
regulation of cell cycleGO:00517262810.018
regulation of transferase activityGO:00513382630.018
salivary gland developmentGO:0007431370.018
cellular lipid metabolic processGO:00442553230.018
protein localization to organelleGO:00333651850.018
skeletal system morphogenesisGO:00487052030.018
regulation of neuron differentiationGO:00456642810.018
organ growthGO:00352651170.018
mapk cascadeGO:00001652810.018
ossificationGO:00015032160.017
stem cell developmentGO:00488642190.017
regulation of endopeptidase activityGO:0052548890.017
establishment of protein localization to organelleGO:00725941180.017
sodium ion transportGO:0006814730.017
mucopolysaccharide metabolic processGO:1903510250.017
cation transportGO:00068123990.017
wound healingGO:00420601570.017
plasma membrane organizationGO:0007009900.017
ras protein signal transductionGO:0007265770.017
regulation of angiogenesisGO:0045765810.017
reactive oxygen species metabolic processGO:0072593840.017
regulation of cellular component sizeGO:00325351210.017
retina development in camera type eyeGO:00600411190.017
protein importGO:00170381010.017
regulation of protein transportGO:00512231630.016
regulation of body fluid levelsGO:00508781620.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.016
cardiac muscle fiber developmentGO:004873940.016
macromolecule catabolic processGO:00090572810.016
endomembrane system organizationGO:00102561470.016
chondroitin sulfate metabolic processGO:0030204170.016
regulation of protein secretionGO:0050708820.016
cellular response to x rayGO:007148120.016
cellular response to hormone stimulusGO:00328701500.016
protein secretionGO:00093061110.016
intracellular protein transportGO:00068862040.016
regulation of epithelial cell proliferationGO:00506781410.016
reactive oxygen species biosynthetic processGO:190340980.016
regulation of kinase activityGO:00435492490.016
positive regulation of cell developmentGO:00107202370.016
respiratory tube developmentGO:00303231670.016
regulation of proteolysisGO:00301621640.016
positive regulation of apoptotic processGO:00430652170.016
positive regulation of programmed cell deathGO:00430682180.016
positive regulation of hydrolase activityGO:00513451480.016
positive regulation of epithelial cell proliferationGO:0050679680.016
regulation of cell migrationGO:00303342190.016
regulation of actin filament based processGO:0032970990.015
sensory perception of soundGO:0007605970.015
rhythmic processGO:00485111740.015
regulation of secretion by cellGO:19035302490.015
cardiac muscle cell differentiationGO:0055007690.015
salivary gland morphogenesisGO:0007435330.015
response to radiationGO:00093141650.015
kidney developmentGO:00018222130.015
negative regulation of protein metabolic processGO:00512482820.015
placenta developmentGO:00018901400.015
regulation of reactive oxygen species metabolic processGO:2000377400.015
antimicrobial peptide productionGO:000277520.015
gland developmentGO:00487323300.015
pallium developmentGO:00215431200.015
transmembrane transportGO:00550854120.015
organonitrogen compound biosynthetic processGO:19015661920.015
regulation of protein bindingGO:0043393600.015
regulation of protein targetingGO:1903533610.015
endothelial cell proliferationGO:0001935270.015
rho protein signal transductionGO:0007266320.015
cellular response to lipidGO:00713961450.015
response to lipopolysaccharideGO:00324961280.015
antibacterial peptide productionGO:000277820.014
neuron deathGO:00709971540.014
ameboidal type cell migrationGO:00016671280.014
regulation of cytokine productionGO:00018172660.014
digestive system developmentGO:00551232000.014
regulation of ion transportGO:00432692150.014
notch signaling pathwayGO:0007219710.014
regulation of secretionGO:00510462740.014
embryonic organ morphogenesisGO:00485622760.014
appendage developmentGO:00487361660.014
epithelial tube morphogenesisGO:00605623030.014
proteoglycan metabolic processGO:0006029380.014
microtubule cytoskeleton organizationGO:00002261570.014
protein import into nucleusGO:0006606950.014
spermatid developmentGO:00072861080.014
mesenchyme developmentGO:00604851520.014
cellular macromolecule catabolic processGO:00442652060.014
cell matrix adhesionGO:0007160680.014
regulation of organelle organizationGO:00330432890.014
positive regulation of mapk cascadeGO:00434101700.014
regulation of erk1 and erk2 cascadeGO:0070372710.014
single organism cell adhesionGO:00986021560.014
glycoprotein metabolic processGO:00091001160.014
cellular response to organonitrogen compoundGO:00714171450.014
heart trabecula morphogenesisGO:0061384260.014
regulation of cellular response to stressGO:00801351590.013
mesoderm developmentGO:00074981000.013
antimicrobial peptide biosynthetic processGO:000277720.013
t cell activationGO:00421102890.013
regulation of map kinase activityGO:00434051200.013
regulation of homeostatic processGO:00328441820.013
defense response to other organismGO:00985421970.013
trabecula formationGO:0060343240.013
regulation of interleukin 1 alpha productionGO:003265040.013
morphogenesis of an epithelial sheetGO:0002011270.013
regulation of macrophage migration inhibitory factor signaling pathwayGO:200044610.013
synaptic transmission cholinergicGO:000727170.013
protein maturationGO:00516041760.013
inflammatory responseGO:00069542440.013
axon guidanceGO:00074111410.013
positive regulation of cytokine productionGO:00018191740.013
regulation of androgen receptor signaling pathwayGO:006076530.013
axonogenesisGO:00074092740.013
regulation of protein serine threonine kinase activityGO:00719001570.013
calcium ion transportGO:00068161590.013
cardiac muscle tissue developmentGO:00487381300.013
negative regulation of cellular component organizationGO:00511291940.013
response to acid chemicalGO:00011011110.013
regulation of cell sizeGO:0008361720.013
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.013
synapse organizationGO:00508081250.013
response to hypoxiaGO:0001666580.013
positive regulation of neuron projection developmentGO:0010976790.013
asymmetric neuroblast divisionGO:005505910.013
spermatogenesisGO:00072832840.013
glycosaminoglycan metabolic processGO:0030203340.013
regulation of protein import into nucleusGO:0042306520.012
positive regulation of fatty acid oxidationGO:004632140.012
developmental maturationGO:00217001930.012
regulation of bindingGO:00510981110.012
cellular response to oxidative stressGO:0034599760.012
regulation of cell growthGO:0001558910.012
telencephalon developmentGO:00215371860.012
regulation of nucleocytoplasmic transportGO:0046822730.012
negative regulation of mapk cascadeGO:0043409650.012
regulation of hydrolase activityGO:00513362460.012
divalent metal ion transportGO:00708381720.012
regulation of ion transmembrane transportGO:00347651190.012
organophosphate biosynthetic processGO:00904071220.012
regulation of multi organism processGO:00439001110.012
negative regulation of angiogenesisGO:0016525250.012
regulation of cardiac muscle contractionGO:0055117210.012
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.012
regulation of cell growth involved in cardiac muscle cell developmentGO:006105030.012
cardiac chamber morphogenesisGO:0003206930.012
synaptic transmissionGO:00072683290.012
ion transmembrane transportGO:00342203610.012
multicellular organismal homeostasisGO:00488711640.012
cellular divalent inorganic cation homeostasisGO:00725031270.012
regulation of membrane potentialGO:00423911920.012
regulation of vasculature developmentGO:1901342880.012
negative regulation of complement activationGO:004591630.012
regulation of cytokine secretion involved in immune responseGO:000273940.012
chemotaxisGO:00069352470.012
contact inhibitionGO:006024230.012
sequestering of metal ionGO:0051238190.012
regulation of vesicle mediated transportGO:00606271390.011
biomineral tissue developmentGO:0031214640.011
negative regulation of protein modification processGO:00314001630.011
organic hydroxy compound metabolic processGO:19016152030.011
neuron apoptotic processGO:00514021420.011
positive regulation of cell motilityGO:20001471160.011
protein localization to membraneGO:00726571080.011
stem cell proliferationGO:00720891170.011
organic cyclic compound catabolic processGO:19013612950.011
mitotic cell cycleGO:00002781950.011
peptidyl tyrosine phosphorylationGO:00181081430.011
regulation of morphogenesis of a branching structureGO:0060688530.011
carbohydrate transportGO:0008643620.011
face morphogenesisGO:0060325290.011
sequestering of calcium ionGO:0051208180.011
ovarian follicle developmentGO:0001541400.011
regulation of endothelial cell proliferationGO:0001936230.011
cytokine mediated signaling pathwayGO:00192211150.011
positive regulation of endopeptidase activityGO:0010950430.011
regulation of defense response to bacteriumGO:190042430.011
striated muscle tissue developmentGO:00147062930.011
cardiac chamber developmentGO:00032051080.011
fertilizationGO:00095661270.011
regulation of protein maturationGO:1903317960.011
hair cycleGO:0042633900.011
extracellular fibril organizationGO:004320620.011
tissue remodelingGO:00487711020.011
negative regulation of intracellular signal transductionGO:19025321670.011
negative regulation of wnt signaling pathwayGO:0030178730.011
development of primary male sexual characteristicsGO:0046546880.011
peptidyl tyrosine modificationGO:00182121450.011
regulation of protein kinase activityGO:00458592320.011
cellular ion homeostasisGO:00068731650.011
locomotory behaviorGO:00076261950.011
negative regulation of signal transduction in absence of ligandGO:1901099160.010
digestive tract developmentGO:00485651900.010
wnt signaling pathwayGO:00160551880.010
response to oxygen levelsGO:0070482620.010
kidney morphogenesisGO:0060993830.010
protein localization to nucleusGO:00345041210.010
cellular response to abiotic stimulusGO:0071214560.010
mineralocorticoid biosynthetic processGO:000670510.010
detection of abiotic stimulusGO:0009582600.010
intrinsic apoptotic signaling pathwayGO:00971931320.010
maintenance of locationGO:0051235890.010
regulation of neuron projection developmentGO:00109751690.010
cellular homeostasisGO:00197252400.010
rhodopsin mediated signaling pathwayGO:001605640.010
peptidyl serine phosphorylationGO:0018105740.010
response to molecule of bacterial originGO:00022371430.010
positive regulation of cytokine secretion involved in immune responseGO:000274120.010
negative regulation of protein activation cascadeGO:200025830.010
antibacterial peptide biosynthetic processGO:000278020.010
cellularizationGO:000734910.010
protein catabolic processGO:00301632210.010
meiotic cell cycle processGO:1903046770.010
regulation of reactive oxygen species biosynthetic processGO:190342620.010
stem cell maintenanceGO:00198271300.010
bone morphogenesisGO:0060349780.010

Naalad2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.070
muscular diseaseDOID:008000000.070
muscle tissue diseaseDOID:6600.070
myopathyDOID:42300.070
musculoskeletal system diseaseDOID:1700.070
nervous system diseaseDOID:86300.032
immune system diseaseDOID:291400.019
congenital muscular dystrophyDOID:005055700.016
muscular dystrophyDOID:988400.016
hematopoietic system diseaseDOID:7400.015
cardiomyopathyDOID:005070000.013
intrinsic cardiomyopathyDOID:006003600.013
heart diseaseDOID:11400.013
cardiovascular system diseaseDOID:128700.013